An agent-based model for simulating the arterial stenosis involved in the vibration-induced Raynaud’s syndrome
Résumé
In this study, we presented a coupled ABM-FEM that simulated the arterial stenosis involved in the vibration-induced Raynaud’s syndrome. The model took into account the change in the secretion of PDGF-BB when the arterial wall was exposed to a low WSS. The PDGF-BB plays a crucial role in proliferation and migration of SMCs. Our model offers the possibility to include additional cellular mechanisms, simulate other mechanical behaviors and study more work conditions with different exposure times.
Domaines
Mécanique [physics]
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https://hal.science/hal-03706107
Soumis le : lundi 27 juin 2022-14:23:53
Dernière modification le : vendredi 28 avril 2023-16:14:12
Archivage à long terme le : lundi 3 octobre 2022-15:39:10
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Identifiants
- HAL Id : hal-03706107 , version 1
Citer
Maha Reda, Christophe Noël, Nicla Settembre, Jérôme Chambert, Arnaud Lejeune, et al.. An agent-based model for simulating the arterial stenosis involved in the vibration-induced Raynaud’s syndrome. American Conference on Human Vibration, Jun 2021, Minneapolis, United States. ⟨hal-03706107⟩
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