. Rodríguez-manzaneque, , p.2, 2002.

. Rodríguez-manzaneque, , p.755, 2002.

. Mata, , p.2

, Integration of linear pMM628 in W303-1B MML756

. Mata,

. Mata, , p.2

. Mata, , p.2

. Mata, , p.2

, Integration of linear pMM657 in W303-1B

, Spore from a cross MML100 Â MML755

. Mml763-mata-grx5hkanmx4, , p.2

, Spore from a cross MML100 Â MML756

, Spore from a cross MML100 Â MML757

, Spore from a cross MML100 Â MML758

, Spore from a cross MML100 Â MML759 MML779 MATa

. Mml780-mata-grx5hkanmx4, , p.2

, Spore from a cross MML100 Â MML779 MML786 MATa, p.2

. Mata, , p.2

. Mata,

, Spore from a cross MML100 Â MML786

, Spore from a cross MML100 Â MML787

. Mml810-mata-grx5hkanmx4, , p.2

, Spore from a cross MML100 Â MML788

R. Achebach, S. Tran, Q. H. Vlamis-gardikas, A. Mullner, M. Holmgren et al., Stimulation of Fe-S cluster insertion into apoFNR by E. coli glutaredoxins 1, 2 and 3 in vitro, FEBS Lett, vol.565, pp.203-206, 2004.

J. N. Agar, B. Krebs, J. Frazzon, B. H. Huynh, D. R. Dean et al., IscU as a scaffold for iron-sulfur cluster biosynthesis: sequential assembly of, Biochemistry, vol.39, pp.7856-7862, 2000.

R. Balasubramanian, G. Shen, D. A. Bryant, and J. H. Golbeck, Regulatory roles for IscA and SufA in iron homeostasis and redox stress responses in the cyanobacterium Synechococcus sp. strain PCC 7002, J Bacteriol, vol.88, pp.3182-3191, 2006.

J. Balk and S. Lobreaux, Biogenesis of iron-sulfur proteins in plants, Trends Plant Sci, vol.10, pp.324-331, 2005.
URL : https://hal.archives-ouvertes.fr/hal-00086047

G. Belli, J. Polaina, J. Tamarit, D. La-torre, M. A. Rodriguez-manzaneque et al., Structurefunction analysis of yeast Grx5 monothiol glutaredoxin defines essential amino acids for the function of the protein, J Biol Chem, vol.277, pp.37590-37596, 2002.

K. Chandramouli and M. K. Johnson, HscA and HscB stimulate [2Fe-2S] cluster transfer from IscU to apoferredoxin in an ATPdependent reaction, Biochemistry, vol.45, pp.11087-11095, 2006.

K. Chandramouli, M. Unciuleac, S. Naik, D. R. Dean, B. H. Huynh et al., Formation and properties of, Biochemistry, vol.46, pp.6804-6811, 2007.

N. H. Cheng, J. Z. Liu, A. Brock, R. S. Nelson, and K. D. Hirschi, AtGRXcp, an Arabidopsis chloroplastic glutaredoxin, is critical for protection against protein oxidative damage, J Biol Chem, vol.281, pp.26280-26288, 2006.

M. M. Cosper, C. Krebs, H. Hernandez, G. Jameson, M. K. Eidsness et al., Characterization of the cofactor content of Escherichia coli biotin synthase, Biochemistry, vol.43, pp.2007-2021, 2004.

H. A. Dailey, M. G. Finnegan, and M. K. Johnson, Human ferrochelatase is an iron-sulfur protein, Biochemistry, vol.33, pp.403-407, 1994.

K. Diekert, A. De-kroon, G. Kispal, and R. Lill, Isolation and subfractionation of mitochondria from the yeast Saccharomyces cerevisiae, Methods Cell Biol, vol.65, pp.37-51, 2001.

Y. Feng, N. Zhong, N. Rouhier, T. Hase, M. Kusunoki et al., Structural insight into poplar glutaredoxin C1 with a bridging iron-sulfur cluster at the active site, Biochemistry, vol.45, pp.7998-8008, 2006.

W. W. Fish, Rapid colorimetric micromethod for the quantitation of complexed iron in biological samples, Methods Enzymol, vol.158, pp.357-364, 1988.

W. Fu, P. M. Drozdzewski, M. D. Davies, S. G. Sligar, and M. K. Johnson, Resonance Raman and magnetic circular dichroism studies of reduced, J Biol Chem, vol.267, pp.15502-15510, 1992.

C. Gelling, I. A. Dawes, N. Richhardt, R. Lill, and . Mü, Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes, Mol Cell Biol, vol.28, pp.1851-1861, 2008.

D. A. Glauser, F. Bourquin, W. Manieri, and P. Schü-rmann, Characterization of ferredoxin:thioredoxin reductase modified by site-directed mutagenesis, J Biol Chem, vol.279, pp.16662-16669, 2004.

S. Han, R. S. Czernuszewicz, T. Kimura, M. Adams, and T. G. Spiro, Fe 2 S 2 protein resonance Raman revisited: structural variations among adrenodoxin, ferredoxin, and red paramagnetic protein, J Am Chem Soc, vol.111, pp.3505-3511, 1989.

E. Herrero and M. A. De-la-torre-ruiz, Monothiol glutaredoxins: a common domain for multiple functions, Cell Mol Life Sci, vol.64, pp.1518-1530, 2007.

M. A. Huynen, C. A. Spronk, T. Gabaldon, and B. Snel, Combining data from genomes, Y2H and 3D structure indicates that BolA is a reductase interacting with a glutaredoxin, FEBS Lett, vol.579, pp.591-596, 2005.

C. Johansson, K. L. Kavanagh, O. Gileadi, and U. Oppermann, Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria, J Biol Chem, vol.282, pp.3077-3082, 2007.

D. C. Johnson, D. R. Dean, A. D. Smith, and M. K. Johnson, Structure, function, and formation of biological iron-sulfur clusters, Annu Rev Biochem, vol.74, pp.247-281, 2005.

M. K. Johnson and A. D. Smith, Iron-sulfur proteins, Encyclopedia of Inorganic Chemistry, King RB, pp.2589-2619, 2005.

G. Layer, S. A. Gaddam, C. N. Ayala-castro, S. Ollagnier-de-choudens, D. Lascoux et al., SufE transfers sulfur from SufS to SufB for iron-sulfur cluster assembly, J Biol Chem, vol.282, pp.13342-13350, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00374619

R. Lill and . Mü, Iron-sulfur-protein biogenesis in eukaryotes, Trends Biochem Sci, vol.30, pp.133-141, 2005.

C. H. Lillig, C. Berndt, O. Vergnolle, M. E. Lonn, C. Hudemann et al., Characterization of human glutaredoxin 2 as iron-sulfur protein: a possible role as redox sensor, Proc Natl Acad Sci, vol.102, pp.8168-8173, 2005.

M. M. Molina, G. Bellí, M. A. De-la-torre, M. T. Rodríguez-manzaneque, and E. Herrero, Nuclear monothiol glutaredoxins of S. cerevisiae can function as mitochondrial glutaredoxins, J Biol Chem, vol.279, pp.51923-51930, 2004.

M. M. Molina-navarro, C. Casas, L. Piedrafita, G. Bellí, and E. Herrero, Prokaryotic and eukaryotic monothiol glutaredoxins are able to perform the functions of Grx5 in the biogenesis of Fe/S clusters in yeast mitochondria, FEBS Lett, vol.580, pp.2273-2280, 2006.

K. Morimoto, E. Yamashita, Y. Kondou, S. J. Lee, F. Arisaka et al., The asymmetric IscA homodimer with an exposed [2Fe-2S] cluster suggests the structural basis of the Fe-S cluster biosynthetic scaffold, J Mol Biol, vol.360, pp.117-132, 2006.

U. Mü-hlenhoff, J. Gerber, N. Richhardt, and R. Lill, Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p, EMBO J, vol.22, pp.4815-4825, 2003.

L. Ojeda, G. Keller, U. Mü-hlenhoff, J. C. Rutherford, R. Lill et al., Role of glutaredoxin-3 and glutaredoxin-4 in the iron regulation of the Aft1 transcriptional activator in S. cerevisiae, J Biol Chem, vol.281, pp.17661-17669, 2006.

A. Picciocchi, C. Saguez, A. Boussac, C. Cassier-chauvat, and F. Chauvat, CGFS-type monothiol glutaredoxins from the cyanobacterium Synechocystis PCC6803 and other evolutionary distant model organisms possess a glutathione-ligated, Biochemistry, vol.46, pp.15018-15026, 2007.

N. Ravi, J. M. Bollinger, B. H. Huynh, D. E. Edmondson, and J. Stubbe, Mechanism of assembly of the tyrosyl radical-diiron(III) cofactor of E. coli ribonucleotide reductase. 1. Mössbauer characterization of the diferric radical precursor, J Am Chem Soc, vol.116, pp.8007-8014, 1994.

R. Jr, J. B. Brent, L. G. Sumegi, B. Srere, and P. A. , Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in S. cerevisiae, Mitochondria: a Practical Approach, vol.19, pp.8180-8190, 1987.

M. T. Rodríguez-manzaneque, J. Tamarit, G. Bellí, R. J. Herrero, and E. , Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur clusters, Mol Biol Cell, vol.13, pp.1109-1121, 2002.

N. Rouhier, E. Gelhaye, and J. P. Jacquot, Plant glutaredoxins: still mysterious reducing systems, Cell Mol Life Sci, vol.61, pp.1266-1277, 2004.
DOI : 10.1007/s00018-004-3410-y

N. Rouhier, H. Unno, S. Bandyopadhyay, L. Masip, S. K. Kim et al., ) Functional, structural and spectroscopic characterization of a glutathioneligated [2FeÀ2S] cluster in poplar glutaredoxin C1, Proc Natl Acad Sci, vol.104, pp.7379-7384, 2007.

K. Sipos, H. Lange, Z. Fekete, P. Ullmann, R. Lill et al., Maturation of cytosolic iron-sulfur proteins requires glutathione, J Biol Chem, vol.277, pp.26944-26949, 2002.

P. J. Stephens, A. J. Thomson, J. Dunn, T. A. Keiderling, J. Rawlings et al., Circular dichroism and magnetic circular dichroism of iron-sulfur proteins, Biochemistry, vol.17, pp.4770-4778, 1978.

J. Tamarit, G. Bellí, E. Cabiscol, E. Herrero, and R. J. , Biochemical characterization of yeast mitochondrial Grx5 monothiol glutaredoxin, J Biol Chem, vol.278, pp.25745-25751, 2003.

B. Touraine, J. P. Boutin, A. Marion-poll, J. F. Briat, G. Peltier et al., Nfu2: a scaffold protein required for [4Fe-4S] and ferredoxin iron-sulfur cluster assembly in Arabidopsis chloroplasts, Plant J, vol.40, pp.101-111, 2004.

D. Van-hoewyk, A. Se, C. M. Cohu, S. K. Herbert, P. Kugrens et al., Chloroplast iron-sulfur cluster protein maturation requires the essential cysteine desulfurase CpNifS, Proc Natl Acad Sci, vol.104, pp.5686-5691, 2007.

F. Vilella, R. Alves, M. T. Rodríguez-manzaneque, G. Bellí, S. Swaminathan et al., Evolution and cellular function of monothiol glutaredoxins: involvement in iron-sulfur cluster assembly, Comp Funct Genom, vol.5, pp.328-341, 2004.

R. A. Wingert, J. L. Galloway, B. Barut, H. Foott, P. Fraenkel et al., Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis, Nature, vol.436, pp.1035-1039, 2005.

X. M. Xu and S. G. Moller, AtSufE is an essential activator of plastidic and mitochondrial desulfurases in Arabidopsis, EMBO J, vol.25, pp.900-909, 2006.

T. Yabe, K. Morimoto, S. Kikuchi, K. Nishio, I. Terashima et al., The Arabidopsis chloroplastic NifU-like protein CnfU, which can act as an iron-sulfur cluster scaffold protein, is required for biogenesis of ferredoxin and photosystem I, Plant Cell, vol.16, pp.993-1007, 2004.

H. Ye, A. Se, A. Td, E. A. Pilon-smits, and M. Pilon, CpSufE activates the cysteine desulfurase CpNifS for chloroplastic Fe-S cluster formation, J Biol Chem, vol.281, pp.8958-8969, 2006.

H. Ye, M. Pilon, and E. A. Pilon-smits, CpNifS-dependent ironsulfur cluster biogenesis in chloroplasts, New Phytol, vol.171, pp.285-292, 2006.