A snoRNA that guides the two most conserved pseudouridine modifications within rRNA confers a growth advantage in yeast, RNA, vol.9, issue.7, pp.771-779, 2003. ,
DOI : 10.1261/rna.5240503
rRNA modifications and ribosome function, Trends in Biochemical Sciences, vol.27, issue.7, pp.344-351, 2002. ,
DOI : 10.1016/S0968-0004(02)02109-6
Pseudouridylation of helix 69 of 23S rRNA is necessary for an effective translation termination, Proceedings of the National Academy of Sciences, vol.104, issue.49, pp.19410-19415, 2007. ,
DOI : 10.1073/pnas.0706558104
Ribosome Structure and Activity Are Altered in Cells Lacking snoRNPs that Form Pseudouridines in the Peptidyl Transferase Center, Molecular Cell, vol.11, issue.2, pp.425-435, 2003. ,
DOI : 10.1016/S1097-2765(03)00040-6
Sculpting of the spliceosomal branch site recognition motif by a conserved pseudouridine, Nature Structural Biology, vol.9, issue.12, pp.958-965, 2002. ,
DOI : 10.1038/nsb873
Ribosomal RNA pseudouridines and pseudouridine synthases, FEBS Letters, vol.28, issue.1, pp.17-25, 2002. ,
DOI : 10.1016/S0014-5793(02)02305-0
??35 in the Branch Site Recognition Region of U2 Small Nuclear RNA Is Important for Pre-mRNA Splicing in Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.280, issue.8, pp.6655-6662, 2005. ,
DOI : 10.1074/jbc.M413288200
Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing, The EMBO Journal, vol.17, issue.19, pp.5783-5795, 1998. ,
DOI : 10.1093/emboj/17.19.5783
[18] Protein sequence comparison at genome scale, Methods Enzymol, vol.266, pp.295-322, 1996. ,
DOI : 10.1016/S0076-6879(96)66020-0
A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya, RNA, vol.9, issue.6, pp.711-721, 2003. ,
DOI : 10.1261/rna.5230603
Evolutionary appearance of genes encoding proteins associated with box H/ACA snoRNAs: Cbf5p in Euglena gracilis, an early diverging eukaryote, and candidate Gar1p and Nop10p homologs in archaebacteria, Nucleic Acids Research, vol.28, issue.12, pp.2342-2352, 2000. ,
DOI : 10.1093/nar/28.12.2342
Formation of the conserved pseudouridine at position 55 in archaeal tRNA, Nucleic Acids Research, vol.34, issue.15, pp.4293-4301, 2006. ,
DOI : 10.1093/nar/gkl530
RNA-modifying enzymes, Current Opinion in Structural Biology, vol.13, issue.1, pp.49-55, 2003. ,
DOI : 10.1016/S0959-440X(02)00002-7
RNA-modifying machines in archaea, Molecular Microbiology, vol.292, issue.3, pp.617-629, 2003. ,
DOI : 10.1046/j.1365-2958.2003.03483.x
The expanding snoRNA world, Biochimie, vol.84, issue.8, pp.775-790, 2002. ,
DOI : 10.1016/S0300-9084(02)01402-5
Small Nucleolar RNAs, Cell, vol.109, issue.2, pp.145-148, 2002. ,
DOI : 10.1016/S0092-8674(02)00718-3
RNA-Guided RNA modification: functional organization of the archaeal H/ACA RNP, Genes & Development, vol.19, issue.10, pp.1238-1248, 2005. ,
DOI : 10.1101/gad.1309605
Reconstitution of archaeal H/ACA small ribonucleoprotein complexes active in pseudouridylation, Nucleic Acids Research, vol.33, issue.10, pp.3133-3144, 2005. ,
DOI : 10.1093/nar/gki630
Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAs, Nucleic Acids Research, vol.36, issue.8, pp.2459-2475, 2008. ,
DOI : 10.1093/nar/gkn077
Binding of L7Ae protein to the K-turn of archaeal snoRNAs: a shared RNA binding motif for C/D and H/ACA box snoRNAs in Archaea, Nucleic Acids Research, vol.31, issue.3, pp.869-877, 2003. ,
DOI : 10.1093/nar/gkg175
Identification of 86 candidates for small non-messenger RNAs from the archaeon Archaeoglobus fulgidus, Proceedings of the National Academy of Sciences, vol.99, issue.11, pp.7536-7541, 2002. ,
DOI : 10.1073/pnas.112047299
Small Nucleolar RNAs Direct Site-Specific Synthesis of Pseudouridine in Ribosomal RNA, Cell, vol.89, issue.4, pp.565-573, 1997. ,
DOI : 10.1016/S0092-8674(00)80238-X
Site-Specific Pseudouridine Formation in Preribosomal RNA Is Guided by Small Nucleolar RNAs, Cell, vol.89, issue.5, pp.799-809, 1997. ,
DOI : 10.1016/S0092-8674(00)80263-9
Elements essential for accumulation and function of small nucleolar RNAs directing site-specific pseudouridylation of ribosomal RNAs, The EMBO Journal, vol.18, issue.2, pp.457-469, 1999. ,
DOI : 10.1093/emboj/18.2.457
Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity, Nucleic Acids Research, vol.34, issue.3, pp.826-839, 2006. ,
DOI : 10.1093/nar/gkj482
Dynamic interactions within sub-complexes of the H/ACA pseudouridylation guide RNP, Nucleic Acids Research, vol.35, issue.18, pp.6196-6206, 2007. ,
DOI : 10.1093/nar/gkm673
Reconstitution of Archaeal H/ACA sRNPs and Test of their Activity, Methods Enzymol, vol.425, pp.389-405, 2007. ,
DOI : 10.1016/S0076-6879(07)25016-5
Crystal Structure of a Cbf5-Nop10-Gar1 Complex and Implications in RNA-Guided Pseudouridylation and Dyskeratosis Congenita, Molecular Cell, vol.21, issue.2, pp.249-260, 2006. ,
DOI : 10.1016/j.molcel.2005.11.017
Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:??55-synthase and RNA-guided RNA:??-synthase activities, Nucleic Acids Research, vol.35, issue.16, pp.5610-5624, 2007. ,
DOI : 10.1093/nar/gkm606
Kinetic and thermodynamic characterization of the reaction pathway of box H/ACA RNA-guided pseudouridine formation, Nucleic Acids Research, vol.40, issue.21, pp.10925-10936, 2012. ,
DOI : 10.1093/nar/gks882
Structural Mechanism of Substrate RNA Recruitment in H/ACA RNA-Guided Pseudouridine Synthase, Molecular Cell, vol.34, issue.4, pp.427-439, 2009. ,
DOI : 10.1016/j.molcel.2009.05.005
Structure of Protein L7Ae Bound to a K-Turn Derived from an Archaeal Box H/ACA sRNA at 1.8 ?? Resolution, Structure, vol.12, issue.5, pp.893-903, 2004. ,
DOI : 10.1016/j.str.2004.03.015
The Archaeal sRNA Binding Protein L7Ae has a 3D Structure Very Similar to that of its Eukaryal Counterpart While Having a Broader RNA-binding Specificity, Journal of Molecular Biology, vol.342, issue.3, pp.757-773, 2004. ,
DOI : 10.1016/j.jmb.2004.07.046
The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs, Biochemistry, vol.44, pp.2-9657, 2005. ,
The Cbf5???Nop10 complex is a molecular bracket that organizes box H/ACA RNPs, Nature Structural & Molecular Biology, vol.148, issue.12, pp.1101-1107, 2005. ,
DOI : 10.1038/nsmb1036
Crystal structure of an H/ACA box ribonucleoprotein particle, Nature, vol.269, issue.7109, pp.302-307, 2006. ,
DOI : 10.1073/pnas.2135585100
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA, Nature Structural & Molecular Biology, vol.47, issue.7, pp.740-746, 2009. ,
DOI : 10.1107/S0907444900014736
The Box H/ACA Ribonucleoprotein Complex: Interplay of RNA and Protein Structures in Post-transcriptional RNA Modification, Journal of Biological Chemistry, vol.285, issue.2, pp.805-809, 2010. ,
DOI : 10.1074/jbc.R109.076893
Substrate RNA positioning in the archaeal H/ACA ribonucleoprotein complex, Nature Structural & Molecular Biology, vol.26, issue.12, pp.1189-1195, 2007. ,
DOI : 10.1038/nsmb1336
Long-distance placement of substrate RNA by H/ACA proteins, RNA, vol.14, issue.10, pp.2086-2094, 2008. ,
DOI : 10.1261/rna.1109808
The combination of symbolic and numerical computation for three-dimensional modeling of RNA, Science, vol.253, issue.5025, pp.1255-1260, 1991. ,
DOI : 10.1126/science.1716375
CHARMMing: A New, Flexible Web Portal for CHARMM, Journal of Chemical Information and Modeling, vol.48, issue.9, pp.1920-1929, 2008. ,
DOI : 10.1021/ci800133b
Development and current status of the CHARMM force field for nucleic acids, Biopolymers, vol.40, issue.4, pp.257-265, 2000. ,
DOI : 10.1002/1097-0282(2000)56:4<257::AID-BIP10029>3.0.CO;2-W
DNA Polymorphism: A Comparison of Force Fields for Nucleic Acids, Biophysical Journal, vol.84, issue.3, pp.1421-1449, 2003. ,
DOI : 10.1016/S0006-3495(03)74957-1
3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures, Nature Protocols, vol.7, issue.7, pp.1213-1227, 2008. ,
DOI : 10.1038/nprot.2008.104
Conformational analysis of nucleic acids revisited: Curves+, Nucleic Acids Research, vol.37, issue.17, pp.5917-5929, 2009. ,
DOI : 10.1093/nar/gkp608
Lead(II) as a probe for investigating RNA structure in vivo, RNA, vol.8, issue.4, pp.534-541, 2002. ,
DOI : 10.1017/S1355838201020416
[24] Application of circular dichroism to study RNA folding transitions, Methods Enzymol, vol.317, pp.393-409, 2000. ,
DOI : 10.1016/S0076-6879(00)17026-0
[4] Circular dichroism, Methods Enzymol, vol.246, pp.34-71, 1995. ,
DOI : 10.1016/0076-6879(95)46006-3
A structural, phylogenetic, and functional study of 15.5-kD/Snu13 protein binding on U3 small nucleolar RNA, RNA, vol.9, issue.7, pp.821-838, 2003. ,
DOI : 10.1261/rna.2130503
Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins, The EMBO Journal, vol.19, issue.8, pp.1857-1867, 2004. ,
DOI : 10.1038/sj.emboj.7600181
Structure of H/ACA RNP Protein Nhp2p Reveals Cis/Trans Isomerization of a Conserved Proline at the RNA and Nop10 Binding Interface, Journal of Molecular Biology, vol.411, issue.5, pp.927-942, 2011. ,
DOI : 10.1016/j.jmb.2011.06.022
Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase, Genes & Development, vol.25, issue.22, pp.2409-2421, 2011. ,
DOI : 10.1101/gad.175299.111
Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells, The Journal of Cell Biology, vol.11, issue.2, pp.207-218, 2006. ,
DOI : 10.1091/mbc.11.2.567
URL : https://hal.archives-ouvertes.fr/hal-00090308
Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase,, Biochemistry, vol.49, issue.29, pp.6276-6281, 2010. ,
DOI : 10.1021/bi1006699