Probing interactions in fungal PKS

Abstract : Biosynthesis of polyketides can depend on interactions between the acyl carrier proteins (ACPs) which hold the growing chains and their enzymatic partners. In this issue of Chemistry & Biology, Bruegger and colleagues demonstrate that mechanism-based probes tethered to the ACPs of fungal nonreducing polyketide synthases can provide insights into these contacts.
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https://hal.univ-lorraine.fr/hal-01467279
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Soumis le : mardi 14 février 2017 - 11:58:56
Dernière modification le : jeudi 11 janvier 2018 - 06:25:37

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Kira J Weissman. Probing interactions in fungal PKS. Chemistry & biology, 2013, 20 (9), pp.1089-91. 〈10.1016/j.chembio1.2013.09.001〉. 〈hal-01467279〉

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