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Journal Articles Chemistry & biology Year : 2013

Probing interactions in fungal PKS


Biosynthesis of polyketides can depend on interactions between the acyl carrier proteins (ACPs) which hold the growing chains and their enzymatic partners. In this issue of Chemistry & Biology, Bruegger and colleagues demonstrate that mechanism-based probes tethered to the ACPs of fungal nonreducing polyketide synthases can provide insights into these contacts.
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hal-01467279 , version 1 (14-02-2017)



Kira J Weissman. Probing interactions in fungal PKS. Chemistry & biology, 2013, 20 (9), pp.1089-91. ⟨10.1016/j.chembio1.2013.09.001⟩. ⟨hal-01467279⟩
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