A. , J. Cullum, and J. , DNA amplification and an unstable arginine gene in Streptornyces licidans 66, Molecular and General Genetics, vol.195, issue.1, pp.34-138, 1984.

A. , J. Cullum, and J. , Structure of an amplifiable DNA sequence in Streptomyces lividans 66, Molecular and General Genetics, vol.201, pp.192-197, 1985.

A. Birch, A. Hausler, and R. Hotter, Genome rearrangement and genetic instability in Streptomyces spp., Journal of Bacteriology, vol.172, issue.8, pp.4138-4142, 1990.
DOI : 10.1128/jb.172.8.4138-4142.1990

URL : http://jb.asm.org/content/172/8/4138.full.pdf

C. , K. F. Hopwood, and D. A. , Streptomyces genetics, The Biology of the Actinomycetes, pp.229-286, 1984.

C. , J. Altenbuchner, J. Flett, F. Piendl, W. Platt et al., DNA amplification and genetic instability in Streptomyces, Biotechnology and Genetic Engineering Review, vol.4, pp.59-78, 1986.

C. , J. Kaiser, P. Flett, F. Redenbach, M. &. Rauland et al., Genetic instability in Streptomyces lizlidans 66, Abstracts of the 4th Con fkrence on the Genetics and Molecular Biology of' Industrial Microorganisms o f ' the American Societj-jbr Microbiology, p.19, 1988.

D. , D. L. Schroeder, J. L. Blattner, F. R. Szybalski, W. Sanger et al., A molecular map of coliphage lambda, pp.469-517, 1983.

D. , U. Weston-hafer, K. &berg, and D. E. , Local DNA sequence control of deletion formation in Escherichia coli plasmid pBR322, Genetics, vol.115, pp.41-49, 1987.

D. , N. K. Chater, and K. F. , Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics, Molecular Microbiology, vol.4, issue.1, pp.1679-1680, 1990.

D. , P. Leblond, P. Decaris, B. Simonet, J. M. Microbiologji et al., Characterization of two families of spontaneously amplifiable units of DNA in Streptomyces ambofaciens A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity, Journal oJ'General Analytical Biochemistry, vol.132, pp.6-7, 1983.

H. , M. Hintermann, G. Simonet, J. M. Crameri, R. Piret et al., Certain chromosomal regions in Streptomjws glaucescens tend to carry amplifications and deletions, Moleculur und General Generics, vol.200, pp.375-384, 1985.

H. , D. A. Bibb, M. J. , C. K. Kieser, T. Bruton et al., Genetic Manipulation oj Streptomj'ces -a Laboratorj, 1985.

H. , R. Eckhardt, and T. , Genetic manipulation, Actinomycetes in Biotechnology, pp.89-90, 1988.

J. , A. P. Wells, and R. A. , Hypervariable minisatellites: recombinators or innocent bystanders?, Trends in Genetics, vol.5, pp.367-371, 1989.

K. , L. Staver, M. Tuan, J. Brown, D. Donadio et al., Genetics of erythromycin synthesis in Saccharopolyspora erythraea, Abstracts of the UCLA Symposium of Molecular and Cellular Biology, pp.417-129, 1990.

L. , P. Demuyter, P. Moutier, L. Laakel, M. Decaris et al., Hypervariability, a new phenomenon of genetic instability, related to D N A amplification in Streptomyces ambofaciens, Journal of Bacteriology, vol.171, pp.419-423, 1989.

M. , T. Fritsch, E. F. Sambrook, and J. , Molecular Cloning, a Laboratory Manual, 1982.

P. , B. P. De-boer, J. H. Bron, S. Venema, and G. , Structural plasmid instability in Bacillus subtilis: effect of direct and inverted repeats, Molecular and General Genetics, vol.212, pp.450-458, 1988.

P. , T. G. Anderson, P. Foley, C. Lindenfelser, L. A. Benedict et al., A selection of media for maintenance and taxonomic study of Streptomyces, Antibiotics Annuals, vol.57, pp.947-953, 1956.

R. , M. A. Kuhstoss, S. Huber, M. L. Ford, L. Godfrey et al., Cloningof spiramycin biosynthetic genes and their use in constructing Streptomyces ambofaciens mu tan ts defective in spi ram ycin biosynthesis, Journal of Bacteriology, vol.172, issue.3, pp.790-793, 1990.

R. , M. Lewis, E. Napier, E. , and H. , Occurrence of reiterated D N A sequences in strains of Streptomyces produced by an interspecific protoplast fusion Deletion and amplification of D N A sequences in melanin-negative variants of Streptomyces reticuli, SCHREMPF, pp.501-505, 1981.

E. M. Southern, Detection of specific sequences among DNA fragments separated by gel electrophoresis, Journal of Molecular Biology, vol.98, issue.3, pp.503-508, 1975.
DOI : 10.1016/S0022-2836(75)80083-0

U. , K. Christians, K. M. Dewet, C. A. Potgieter, T. D. Shaw et al., The loss of a large D N A fragment is associated with an aerial mycelium negative (Amy-) phenotype in Streptomyces cattleya, Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors, pp.103-119, 1985.