Henry's clinical diagnosis and management by laboratory methods, pp.3-5, 2011. ,
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2, Biochemical Journal, vol.327, issue.1, pp.305-310, 1997. ,
DOI : 10.1042/bj3270305
Pigment gallstones, Gastroenterology, vol.72, pp.167-182, 1977. ,
Unconjugated bilirubin in human bile: the nucleating factor in cholesterol cholelithiasis?, Journal of Clinical Pathology, vol.56, issue.8, pp.596-598, 2003. ,
DOI : 10.1136/jcp.56.8.596
UGT1A1 variation and gallstone formation in sickle cell disease, Blood, vol.105, issue.3, pp.968-972, 2005. ,
DOI : 10.1182/blood-2004-02-0521
URL : http://www.bloodjournal.org/content/bloodjournal/105/3/968.full.pdf
Rare-Variant Association Analysis: Study Designs and Statistical Tests, The American Journal of Human Genetics, vol.95, issue.1, pp.5-23, 2014. ,
DOI : 10.1016/j.ajhg.2014.06.009
URL : https://doi.org/10.1016/j.ajhg.2014.06.009
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease, Nature Genetics, vol.52, issue.11, pp.1066-1073, 2011. ,
DOI : 10.1159/000090694
Case-only exome sequencing and complex disease susceptibility gene discovery: study design considerations, Journal of Medical Genetics, vol.120, issue.(Suppl 1), pp.10-16, 2015. ,
DOI : 10.1016/j.ophtha.2013.07.052
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503357/pdf
Genetic diagnosis by whole exome capture and massively parallel DNA sequencing, Proceedings of the National Academy of Sciences, vol.25, issue.14, pp.19096-19101, 2009. ,
DOI : 10.1093/bioinformatics/btp324
URL : http://www.pnas.org/content/106/45/19096.full.pdf
Exome sequencing resolves apparent incidental findings and reveals further complexity of SH3TC2 variant alleles causing Charcot-Marie-Tooth neuropathy, Genome Medicine, vol.5, issue.6 ,
DOI : 10.1038/nbt.1975
URL : https://genomemedicine.biomedcentral.com/track/pdf/10.1186/gm461?site=genomemedicine.biomedcentral.com
Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations, Am J Clin Nutr, vol.83, pp.701-707, 2006. ,
Environmental influence on the worldwide prevalence of a 776C->G variant in the transcobalamin gene (TCN2), Journal of Medical Genetics, vol.44, issue.6, pp.363-367, 2007. ,
DOI : 10.1136/jmg.2006.048041
Helicobacter pylori serologic status has no influence on the association between fucosyltransferase 2 polymorphism (FUT2 461 G->A) and vitamin B-12 in Europe and West Africa, American Journal of Clinical Nutrition, vol.95, issue.2, pp.514-521, 2012. ,
DOI : 10.3945/ajcn.111.016410
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion, Nature Genetics, vol.628, issue.2, pp.197-201, 2013. ,
DOI : 10.1093/nar/gkr981
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727235/pdf
Long-Range LD Can Confound Genome Scans in Admixed Populations, The American Journal of Human Genetics, vol.83, issue.1, pp.132-135, 2008. ,
DOI : 10.1016/j.ajhg.2008.06.005
URL : https://doi.org/10.1016/j.ajhg.2008.06.005
Quality Control for Genome-Wide Association Studies, Methods Mol Biol, vol.628, pp.341-372, 2010. ,
DOI : 10.1007/978-1-60327-367-1_19
Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data, The American Journal of Human Genetics, vol.83, issue.3, pp.311-321, 2008. ,
DOI : 10.1016/j.ajhg.2008.06.024
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling, Bioinformatics, vol.22, issue.2, pp.195-201, 2006. ,
DOI : 10.1093/bioinformatics/bti770
The SWISS-MODEL Repository and associated resources, Nucleic Acids Research, vol.37, issue.Database, pp.387-392, 2009. ,
DOI : 10.1093/nar/gkn750
URL : https://academic.oup.com/nar/article-pdf/37/suppl_1/D387/3272538/gkn750.pdf
AstexViewer: a visualisation aid for structure-based drug design, Journal of Computer-Aided Molecular Design, vol.16, issue.12, pp.871-881, 2002. ,
DOI : 10.1023/A:1023813504011
SWISS-MODEL and the Swiss-Pdb Viewer: An environment for comparative protein modeling, Electrophoresis, vol.23, issue.15, pp.2714-2723, 1997. ,
DOI : 10.1007/978-94-011-1472-1_128
Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects, Journal of Human Genetics, vol.299, issue.6, pp.317-323, 2009. ,
DOI : 10.1097/FPC.0b013e3280ef698f
Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia, Human Molecular Genetics, vol.18, issue.14, pp.2711-2718, 2009. ,
DOI : 10.1093/hmg/ddp203
Genome-wide association meta-analysis for total serum bilirubin levels, Human Molecular Genetics, vol.18, issue.14, pp.2700-2710, 2009. ,
DOI : 10.1093/hmg/ddp202
URL : https://academic.oup.com/hmg/article-pdf/18/14/2700/14138838/ddp202.pdf
Loci From a Genome-Wide Analysis of Bilirubin Levels Are Associated With Gallstone Risk and Composition, Gastroenterology, vol.139, issue.6, pp.1942-1951, 2010. ,
DOI : 10.1053/j.gastro.2010.09.003
Mayo Genome Consortia: A Genotype-Phenotype Resource for Genome-Wide Association Studies With an Application to the Analysis of Circulating Bilirubin Levels, Mayo Clinic Proceedings, vol.86, issue.7 ,
DOI : 10.4065/mcp.2011.0178
UGT1A1 is a major locus influencing bilirubin levels in African Americans, European Journal of Human Genetics, vol.40, issue.4, pp.463-468, 2012. ,
DOI : 10.1371/journal.pone.0013577
A Genome-Wide Association Study of Total Bilirubin and Cholelithiasis Risk in Sickle Cell Anemia, PLoS ONE, vol.18, issue.6, p.34741, 2012. ,
DOI : 10.1371/journal.pone.0034741.s001
A Genome-Wide Association Study for Serum Bilirubin Levels and Gene-Environment Interaction in a Chinese Population, Genetic Epidemiology, vol.40, issue.4, pp.293-300, 2013. ,
DOI : 10.1002/hep.1840400412
Pharmacogenomics of human UDP-glucuronosyltransferase enzymes, The Pharmacogenomics Journal, vol.45, issue.182, pp.136-158, 2003. ,
DOI : 10.1002/ajmg.10209
URL : http://www.nature.com/tpj/journal/v3/n3/pdf/6500171a.pdf
Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus, Pharmacogenetics, vol.11, issue.4, pp.357-368, 2001. ,
DOI : 10.1097/00008571-200106000-00011
Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels???The Framingham Heart Study, Atherosclerosis, vol.206, issue.1, pp.228-233, 2009. ,
DOI : 10.1016/j.atherosclerosis.2009.02.039
Genome-wide association of serum bilirubin levels in Korean population, Human Molecular Genetics, vol.19, issue.18, pp.3672-3678, 2010. ,
DOI : 10.1093/hmg/ddq281
A Genome-Wide Search for Non-UGT1A1 Markers Associated with Unconjugated Bilirubin Level Reveals Significant Association with a Polymorphic Marker Near a Gene of the Nucleoporin Family, Annals of Human Genetics, vol.10, issue.1, pp.33-41, 2012. ,
DOI : 10.1091/mbc.10.3.649
Association of polymorphisms in four bilirubin metabolism genes with serum bilirubin in three Asian populations, Human Mutation, vol.7, issue.4, pp.609-615, 2009. ,
DOI : 10.4088/JCP.v61n1110
Common variants of four bilirubin metabolism genes and their association with serum bilirubin and coronary artery disease in Chinese Han population, Pharmacogenetics and Genomics, vol.19, issue.4, pp.310-318, 2009. ,
DOI : 10.1097/FPC.0b013e328328f818
A Molecular Model of the Human UDP-Glucuronosyltransferase 1A1, Its Membrane Orientation, and the Interactions between Different Parts of the Enzyme, Molecular Pharmacology, vol.77, issue.6, pp.931-939, 2010. ,
DOI : 10.1124/mol.109.063289
Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications, Pharmacogenetics, vol.7, issue.6, pp.485-495, 1997. ,
DOI : 10.1097/00008571-199712000-00007
Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation, Hepatology, vol.10, issue.6, pp.1912-1921, 2012. ,
DOI : 10.1186/1471-230X-10-57
Prevalence of Clinically Relevant UGT1A Alleles and Haplotypes in African Populations, Annals of Human Genetics, vol.40, issue.Pt 2, pp.236-246, 2011. ,
DOI : 10.1002/hep.1840400412