.. Les-facteurs-de-différenciation, .. Les-concentrés-plaquettaires, P. Le-pepgen, and .. La-simvastatine, 60 ? Les facteurs de croissance, p.77

B. 1. Ache-m, B. Jp, G. M. , and M. J. , Formes cliniques des préparations prothétiques après hémisection et amputation radiculaire, Actualités Odontostomatologiques, vol.45, issue.173, pp.33-44, 1991.

A. A. Baran-a, G. O. , O. N. , and B. K. , Periodontal regenerative potential of autogenus periodontal ligament grafts in class II furcation defects, Journal of Periodontology, vol.76, pp.595-604, 2005.

A. Habashneh-a, K. Y. , A. Masri-s, and T. D. , Furcation entrance dimensions of the first and second mandibular molars among jordanians, Oral Health and Preventive Dentistry, vol.8, pp.401-406, 2010.

A. F. and O. Jp, Valeur biologique et nouvelles orientations dans l'utilisation des matériaux de substitution osseuse, Journal de Parodontologie et d'Implantologie Orale, vol.19, pp.317-343, 2000.

A. O. , W. Sa, J. Qw, and G. Wv, Plateletderived growth factor gene delivery stimulates ex vivo gingival repair, Tissue Engineering, vol.9, issue.4, pp.745-56, 2003.

B. Jd, G. R. , and H. G. , Periodontal disease and cardiovascular disease, Journal of Periodontology, vol.67, pp.1123-1137, 1996.

B. W. Becker-be, C. R. Prichard-jf, R. E. , and G. , Root Isolation for New Attachment Procedures, Journal of Periodontology, vol.8, issue.12, pp.819-826, 1987.
DOI : 10.1111/j.1600-051X.1986.tb00854.x

B. T. and F. Tf, Implant versus tooth retention from the periodontal perspective, Periodontology, vol.3, issue.3, pp.167-176, 2006.

. Bruxelles, 289 p. 15. BERGENHOLTZ A. Radectomy of multirooted teeth, Journal of the American Dental Association, vol.85, pp.870-875, 1972.

B. Me, La place des lasers en parodontie clinique, Le fil dentaire, vol.39, pp.36-38, 2009.

B. A. Disponible-sur, M. , B. Ba, W. Rc, and N. Hw, Chirurgie plastique parodontale 2e édition. Rueil-Malmaison : Editions CdP The role of individual and neighborhood social factors on periodontitis : the third National Health and Nutrition Examination Survey, Journal of Periodontology, vol.77, issue.3, pp.444-53, 2006.

B. Pj, L. Lc, M. R. Moy-pk, N. M. , S. Db et al., De novo bone induction by recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillary sinus floor augmentation, Journal of Oral Maxillofacial Surgery, vol.63, pp.1693-1707, 2005.

B. B. , R. P. , and D. Monck-d-'uzer-o, Spécificité parodontale des molaires les lésions inter-radiculaires, Réalités Cliniques, vol.19, issue.4, pp.1014-1021, 2008.

B. H. Calas-bennsar-i, B. P. , J. O. , O. V. , and G. P. , Taux de survie des dents pluriradiculées après résection de racines : essai de comparaison avec le taux de longévité des implants alloplastiques, International Journal of Periodontics and Restorative Dentistry, vol.14, issue.23, pp.537-543, 1994.

C. G. , D. Febo-g, T. Mp, M. C. , and F. Ma, A retrospective analysis of the periodontal-prosthetic treatment of molars with interradicular lesions, International Journal of Periodontics and Restorative Dentistry, vol.11, issue.3, pp.189-205, 1991.

C. Rcv, R. Edp, R. Fv, F. Jr, S. Aw et al., Influence of anatomic features on the effectiveness of enamel matrix derivative proteins in the treatment of proximal class II furcation involvements, Quintessence International, vol.40, issue.9, pp.753-761, 2009.

C. Rcv, R. Edp, F. Jr, S. Aw, A. Gmb et al., Enamel matrix derivative proteins for the treatment of proximal class II furcation involvements : a prospective 24-months randomized clinical trial, Journal of Clinical Periodontology, vol.37, pp.1100-1109, 2010.

C. Pc, C. J. , J. Q. , S. Yj, S. Jv et al., Adenovirus encoding human platelet-derived growth factor-B delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use

C. P. , P. Prato-g, and T. M. , Long term stability of clinical attachment following guided tissue regeneration and conventional therapy, Journal Of Clinical Periodontology, vol.23, pp.106-111, 1996.

D. B. , L. Np, T. Ms, and E. P. , Supportive periodontal therapy of furcation sites : non-surgical instrumentation with or without topical doxycycline, Journal of Clinical Periodontoly, vol.36, pp.514-522, 2009.

D. Almeida, J. , T. Lh, N. Bosco-af, O. M. Mj et al., In Vivo Effect of Photodynamic Therapy on Periodontal Bone Loss in Dental Furcations, Journal of Periodontology, vol.17, issue.6, pp.1081-1089, 2008.
DOI : 10.1089/1549541041438623

D. Andrade-pf, D. Souza-sls, D. Oliveira-macedo-g, N. J. Ab, D. Moraes et al., Acellular Dermal Matrix as a Membrane for Guided Tissue Regeneration in the Treatment of Class II Furcation Lesions: A Histometric and Clinical Study in Dogs, Journal of Periodontology, vol.16, issue.7, pp.1288-1299, 2007.
DOI : 10.1902/jop.1975.46.12.701

D. Peloso-ribeiro-e, H. Bittencourt-s, F. Jr, S. E. , and S. A. Zaffalon, Comparative Study of Ultrasonic Instrumentation for the Non-Surgical Treatment of Interproximal and Non-Interproximal Furcation Involvements, Journal of Periodontology, vol.101, issue.2, pp.224-230, 2007.
DOI : 10.1902/jop.1987.58.2.86

D. Cg and V. Kl, Comparative evaluation of PepGen, p.15

L. Bio-oss, Y. P. , and G. S. , Disponible sur: http://www.dmitryvassilenko.org Stromal cell-derived factor-1 significantly induces proliferation, migration, and collagen type I expression in a human periodontal ligament stem cell subpopulation, 37. DMITRY VASSILENKO. [en ligne], pp.527-530, 2003.

E. Ir and D. Ga, Morphological classification of furcation

E. Jr and B. J. , A review of the periodontal, endodontic, and prosthetic considerations in odontogenous resection procedures, International Journal of Periodontics and Restorative Dentistry, vol.6, issue.2, pp.34-57, 1986.

E. P. , P. B. , H. R. , and K. Ts, Long-term results of guided tissue regeneration therapy with non-resorbable and bioabsorbable barriers

E. Sharkawy-h, K. A. , D. J. , H. H. , L. H. et al., Platelet-Rich Plasma: Growth Factors and Pro- and Anti-Inflammatory Properties, Journal of Periodontology, vol.269, issue.1, pp.661-669, 2007.
DOI : 10.4049/jimmunol.164.4.1663

E. D. , E. Jaffali-k, and D. C. , Traitement des lésions interradiculaires molaires. Les cas limites, Journal de Parodontogie et d'Implantologie Orale, vol.2, pp.145-163, 1997.

E. Al, J. J. , J. M. De, A. Ns, D. Araujo-vc et al., Use of anorganic bovine-derived hydroxyapatite matrix/cell-binding peptide (P-15) in the treatment of class II furcation defects : A clinical and radiographic study in humans, Journal of Periodontology, vol.78, pp.2277-2283, 2007.

F. Dg-fleischer-n, . De-wall-h, and . Bloom, Clinical study of cell-binding peptide (PepGen-P15®) application in advanced periodontal lesions of dogs Mémoire de Maitrise à Faculty of Veterinary Medicine and Zootechny : Universidade Sao Paulo Régénération chez le chien de l'appareil d'attache perdu : utilisation d'une résille résorbable en vicryl (Polyglactine 910), pp.45-55, 1988.

G. Rj and L. H. , The role of systemic conditions and disorders in periodontal disease, Periodontology, vol.2, pp.98-116, 20001993.

G. Nd, G. F. , S. A. , and D. N. , Wound healing following regenerative procedures in furcation degree III defects : histomorphometric outcomes, Clinical Oral Investigations, vol.16, pp.239-249, 2012.

G. Pf, G. Bcv, P. Sp, S. Ea, S. Aw et al., Effect of two different approaches for root decontamination on new cementum formation following guided tissue regeneration : a histomorphometric study in dogs, Journal of Periodontal Research, vol.41, pp.535-540, 2006.

G. Sg and G. Rj, Periodontal disease and diabete mellitus : a two-way relationship, Annals of Periodontology, vol.3, pp.51-61, 1998.

H. Se, N. S. , and L. J. , Periodontal treatment of multirooted teeth. Results after 5 years, Journal of Clinical Periodontology, vol.2, pp.126-161, 1975.

H. Tc and K. Ks, Genetic factors in the pathogenesis of periodontitis, Periodontology 2000, vol.14, pp.202-217, 1997.

H. Autorité, D. Santé, J. J. He, S. Ke, S. Ls et al., Evaluation et recommandation de l'Inductos® Disponible sur: http://www.has-sante.fr (consulté le 22/03/14) 65 Emdogain promotes osteoblast proliferation and differentiation and stimulates osteoprotegerin expression. Oral Surgery, Oral Radiology and Endodontology, vol.97, issue.2, pp.239-284, 2004.

H. Pj and C. Sr, The furcation involvement : A classification of bone deformities, Periodontics, vol.6, pp.84-86, 1968.

H. Wh and S. Rg, Intraoral transplants of cancellous bone and marrow in periodontal lesions, Journal of Periodontology, vol.44, pp.194-208, 1973.

H. Gl and T. Cc, Relationship between periodontal furcation involvement and molar cervical enamel projections, Journal of Periodontology, vol.58, pp.715-721, 1987.

H. Lr, J. Aa, M. Mcguire, M. Jt, S. J. et al., Application of periodontal tissue engineering using enamel matrix derivative and a human fibroblast-derived dermal substitute to stimulate periodontal wound healing in class III furcation defects, Journal of Periodontology, vol.77, pp.790-799, 2006.

H. H. , F. Jp, P. Dw, O. S. , G. Wv et al., A phase I/II clinical trial to evaluate a combination of recombinant human platelet-derived growth factor-BB and recombinant human insulin-like growth factor-I in patients with periodontal disease, Journal of Periodontology, vol.68, pp.1186-1193, 1997.

H. O. , T. H. , and D. Jl, Du contrôle de la plaque au contrôle de l'infection, L'information dentaire, vol.3, 2011.

H. M. , N. Dg, and U. A. , A clinical evaluation of bioactive glass particulate in the treatment of mandibular class II furcation defects, Brazilian Journal of Oral Sciences, vol.6, issue.23, pp.1450-1456, 2007.

J. Q. , A. O. , W. Sa, P. Ma, and G. Wv, Engineering of tooth-supporting structures by delivery of PDGF gene therapy vectors, Molecular Therapy, vol.9, issue.4, pp.519-526, 2004.

K. Wb, K. Kl, and P. Kd, A review of longitudinal studies that compared periodontal therapies, Journal of Periodontology, vol.64, pp.243-53, 1993.

K. H. , H. A. Hasegawa-n, I. T. , H. H. , S. H. et al., Enhancement of periodontal tissue regeneration by transplantation of bone marrow mesenchymal stem cells, Journal of Periodontology, vol.75, pp.1281-1287, 2004.

K. H. and V. Kl, Clinical and radiographic evaluation of human periodontal osseous defect (mandibular grade II furcation) treated with PepGen P-15 and a bioresorbable membrane (Atrisorb), Journal of Indian Society of Periodontology, vol.16, issue.4, pp.569-76, 2012.

K. Bm, S. J. , N. A. , S. M. , and B. M. , Treatment of class II molar furcation involvement : Meta-Analyses of reentry results, Journal of Periodontology, vol.82, pp.413-428, 2011.

K. P. , S. V. , K. A. , and S. Hp, Imperative role of prosthodontist in the management of furcation defect of mandibular molar, E- Journal of Dentistry, vol.2, issue.2, pp.176-180, 2012.

L. B. Stein-sd and W. B. , An evaluation of root resections

L. J. Liu-y, Z. Y. , D. G. , F. D. , Z. C. et al., Periodontal Ligament Stem Cell-Mediated Treatment for Periodontitis in Miniature Swine, Stem Cells, vol.282, issue.4, pp.1065-73, 1989.
DOI : 10.1902/jop.1991.62.9.548

L. H. and B. Lj, Early onset periodontitis in the United States of America, Journal of Periodontology, vol.62, pp.608-624, 1991.

L. Se, R. De-castilla-g, W. R. , K. Cp, H. Th et al., The effects of short term application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing, Journal of Periodontology, vol.62, pp.458-467, 1991.

M. Dh and H. Sw, Projections of cervical enamel into molar furcations, Journal of Periodontology, vol.33, pp.49-53, 1964.

M. J. Bissada-n and M. J. , Efficiency of scaling of the molar furcation area with and without surgical access, International Journal of Periodontics and Restorative Dentistry, vol.6, pp.24-35, 1986.

M. Fall and . Jr, Tooth loss in 100 treated patients with periodontal disease. A long term study, Journal of Periodontology, vol.53, pp.539-549, 1982.

B. Mcallister, Stem cell-containing allograft matrix enhances periodontal regeneration : case presentations, International Journal of Periodontics and Restorative Dentistry, vol.31, issue.2, pp.149-155, 2011.

M. Jt, Decalcified freeze-dried bone allografts as an implant material in human periodontal defect, International Journal of Periodontics and Restorative Dentistry, vol.4, pp.41-55, 1984.

M. Jt, D. P. Valderrama-m, and C. Dl, Histological and Clinical Evaluation of recombined human platelet-derived growth factor combined with beta tricalcium phosphate for the treatment of human class III furcation defects, The International Journal of Periodontics and Restorative Dentistry, vol.29, issue.2, pp.169-177, 2009.

M. Ms, L. Y. , L. Mt, G. Pj, M. Schmid-mj et al., Injectable simvastatin in periodontal defects and aleolar ridges : Pilot studies, Journal of Periodontology, vol.79, pp.1465-1473, 2008.

M. Ch, N. M. , and R. Babu-t, Multidisciplinary approche for management of mandibular molar with furcation involvement-A case report. Surgical and clinical techniques Annals and Essences of, Dentistry, vol.2, issue.3, pp.120-123, 2010.

N. M. Sato-s, K. H. , and K. K. , Effects of application of platelet releasate in periodontal regeneration therapy, International Journal of Periodontics and Restorative Dentistry, vol.25, issue.6, pp.571-83, 2005.

N. Av and P. Rc, Common criteria followed by dentists for extration of periodontically weakened teeth, Annals and Essences of Dentistry, vol.2, issue.4, pp.33-35, 2010.

N. Me, Understanding the etiology of periodontitis : an overview of periodontal risk factors, Periodontology, vol.32, pp.11-23, 2000.

P. Sy, S. Sy, Y. Sm, and K. Sb, Factors influencing the outcome of root-resection therapy in molars : A 10 year retrospectie study, Journal of Periodontology, vol.80, pp.32-40, 2009.

P. Jy, J. Sh, and C. Ph, Efficacy of periodontal stem cell transplantation in the treatment of advanced periodontitis, Cell Transplant, vol.20, issue.2, pp.271-85, 2011.

P. Aef, P. Db, A. Jr, S. Sls, M. Taba-jr et al., Bioactive glass with or without enamel matrix derivative in class II furcation lesions : Histomorphometric study in dogs, Periodontology, vol.3, issue.2, pp.105-113, 2006.

P. Ar, P. S. , G. G. , D. P. , and S. Sk, A randomized clinical trial of autologous platelet rich plasma in treatment of mandibular degree II furcation defects, Journal of Clinical Periodontology, vol.36, pp.581-588, 2009.

P. Ar, P. N. , K. N. , N. Sb, S. Sp et al., Clinical efficacy of subgingivally delivered 1,2-mg simvastatin in the treatment of individuals with calss II furcation defects : A randomized controlled clinical trial, Journal of Periodontology, vol.83, pp.1472-1479, 2012.

R. Hf, L. Z. , O. B. , P. Ch, and G. Wv, Cell and gene based therapeutic strategies for periodontal regenerative medicine, Journal of Periodontology, vol.82, issue.9, pp.1223-1260, 2011.

R. Vm, S. Sls, M. Taba-jr, P. Db, and G. Mfm, Treatment of class III furcation defects with expanded polytetrafluoroethylene membrane associated or not with anorganic bone matrix/synthetic cell-binding peptide : A histologic and histomorphometric study in dogs, Journal of Periodontology, vol.77, pp.490-497, 2006.

R. Ae, L. Kg, R. Mccormick-cm, and . Da, Stress, Depression, cortisol, and periodontal disease, Journal of Periodontology, vol.80, pp.260-266, 2009.

S. Naoshi, Atlas Clinique de Chirurgie Parodontale, Quintessence International, vol.447, 2002.

S. Rg, H. Wh, and B. W. , Iliac transplants in periodontal therapy, Journal of Periodontoly, vol.41, pp.566-580, 1970.

S. Rg, . Mc, and . Pk, Combined osseous composite grafting, root conditioning and guided tissue regeneration, International Journal of Periodontics and Restorative Dentistry, vol.4, pp.9-31, 1988.

S. A. , C. Gc, W. P. , and D. N. , Clinical and histologic evaluation of treatment of infrabony defects with an enamel matrix protein derivative (Emdogain), International Journal of Periodontics and Restorative Dentistry, vol.20, pp.375-381, 2000.

S. Z. Somers-a, M. Jt, C. Dl-jr, D. Dd, C. Dl et al., Ability of commercial demineralized freeze-dried bone allograft to induce new bone formation is dependent on donor age but not gender, Journal of Periodontology, vol.69, issue.4, pp.470-478, 1998.

S. Bm, M. M. , G. S. , B. Pm, B. S. et al., Investigation of multipotent postnatal stem cells from human periodontal ligament, Lancet, vol.364, issue.9429, pp.149-55, 2004.

S. M. , D. E. , A. M. , V. S. , and E. B. Karimi, The effect of platelet-rich plasma (PRP) and Bio-oss on bone regeneration in furcation class II defects : A histologic and histomorphometric study in dogs, Shiraz University Dental Journal, vol.12, issue.1, pp.1-10, 2011.

S. A. and P. Ar, Autologous platelet-rich fibrin in the treatment of mandibular degree II furcation defects : A randomized clinical trial, Journal of Periodontology, vol.82, pp.1396-1403, 2011.

S. Sb, K. Gc, B. S. , and C. Bo, Comparison of mesenchymal stem cells and autogenous cortical bone graft in the treatment of class II furcation defects in dogs, Clinical Oral Investigations, vol.16, issue.1, pp.251-258, 2012.

. Smart, The assessment of ultrasonic root surface debridement by determination of residual endotoxin levels, Journal of Clinical Periodontology, vol.13, issue.3, pp.174-178, 1990.
DOI : 10.1177/00220345840630091401

S. Française-de-parodontologie, Implantologie Oral (SFPIO) Les recommandations de la SFPIO, position de la SFPIO sur le PRF, 2011.

S. K. , S. V. , L. Ta, H. M. , B. M. et al., An evaluation of bioactive glass in the treatment of periodontal defects : a meta-analysis of randomized controlled clinical trials, Journal of Periodontology, vol.83, issue.4, pp.453-464, 2012.

S. Ha, P. Rl, and B. Idg, Cigarette smoking and periodontal disease, Journal of American Dental Association, vol.77, pp.1081-1085, 1968.

S. Fa, M. Go, A. Jr, S. Borges-gj, . Sls et al., The bone formation capabilities of the anorganic bone matrix-synthetic cell-binding peptide 15 grafts in an animal periodontal model : A histologic and histomorphometric study in dogs, Journal of Periodontology, vol.81, pp.584-603, 2010.

S. Ff, R. Fv, R. Tl, S. Kg, C. Md et al., Autologous periodontal ligament cells in the treatment of class II furcation defects : a study in dogs, Journal of Clinical periodontology, vol.38, pp.491-498, 2011.

S. Ff, R. Fv, S. Gomes-trl, S. Kg, C. Md et al., Autologous periodontal ligament cells in the treatment of class III furcation defects : a study in dogs, Journal of Clinical Periodontology, vol.39, pp.377-384, 2012.

S. G. and W. Jl, Furcation topography of the maxillary and mandibular first molars, Journal of Clinical Periodontology, vol.15, pp.271-275, 1988.

T. Tf and D. B. , Platelet-rich plama : a promising innovation in dentistry, Journal of the Canadian Dental Association, vol.69, issue.10, p.664, 2003.

U. Mr and . Bone, Formation by autoinduction, Science, vol.150, pp.893-899, 1965.

W. N. , G. P. Liao-d, Y. X. , L. W. , L. Y. et al., Autotransplanted mesenchymal stromal cell fate in periodontal tissue of beagle dogs, Cytotherapy, vol.12, issue.4, pp.514-535, 2010.

W. Dh, B. Rl, and G. Dm, Platelet gel : an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery, Journal of Oral Maxillofacial Surgery, vol.55, pp.1294-1299, 1997.

A. Jc, R. Am, H. L. Hj, L. Haugen-hj, and . Sp, Microcomputed tomographic and histologic analysis of animal experimental degree II furcation defects treated with porous titanium granules or deproteinized bovine bone, Journal of Periodontology, vol.83, pp.211-221, 2012.

W. Jc, L. Sp, H. L. , and A. Am, Porous titanium granules in the treatment of mandibular class II furcation defects : A consecutive case series, Journal of Periodontology, vol.83, pp.61-69, 2012.

Y. Hg and B. H. , Clinical evaluation of chlorhexidine and essential oils for adjunctive effects in ultrasonic instrumentation of furcation involvements: a randomized controlled clinical trial, International Journal of Dental Hygiene, vol.10, pp.113-117, 2012.

Z. Gg, K. A. Hoffmann-o, W. B. , D. G. , and T. Dn, Mandibular molar root resection versus implant therapy : A retrospective nonrandomized study, Journal of Oral Implantology, vol.35, issue.2, pp.52-62, 2009.