9% (9-27.7) par secteur, de 294% (15.1-47.5) par lobe et de 455% (24.4-67.8) par patient Dans le bras sans diffusion ,
2% (84-95.9) par secteur, de 83.3% (62.6- 95.3) par lobe et de 85.7% (42.1-99.6) par patient Dans le bras sans diffusion, pp.90-96 ,
VPP et VPN de chaque bras, gold standard biopsies b. En comparaison aux prostatectomies i ,
4-91.9) par secteur, de 100% (61.5-100) par lobe et de 100% (51.7-100) par patient Dans le bras sans diffusion, p.80 ,
6-87.3) par secteur, pp.60-74 ,
2% (15-44.9), celle de la séquence de perfusion de 18% (7.5-33.5) et celle de la séquence de diffusion de 30 ,
5% (32.2-75.6), celle de la séquence de perfusion de 27.3% (10.7-50.2) et celle de la séquence de diffusion de 46, pp.100-142 ,
VPP et VPN de chaque paire (gold standard biopsies) 2) Gold standard : prostatectomie a. Sensibilité, spécificité ,
Cancer Statistics, 2005, CA: A Cancer Journal for Clinicians, vol.55, issue.1, pp.10-30, 2005. ,
DOI : 10.3322/canjclin.55.1.10
Cancer incidence and mortality in France over the period 1980???2005, Revue d'??pid??miologie et de Sant?? Publique, vol.56, issue.3, pp.159-75, 2008. ,
DOI : 10.1016/j.respe.2008.03.117
URL : https://hal.archives-ouvertes.fr/inserm-00338335
Multiple cancers in the prostate. Morphologic features of clinically recognized versus incidental tumors, Cancer, vol.147, issue.9, pp.2313-2321, 1992. ,
DOI : 10.1002/1097-0142(19921101)70:9<2313::AID-CNCR2820700917>3.0.CO;2-T
Carcinoma of the prostate: Prognostic evaluation of certain pathologic features in 208 radical prostatectomies, Cancer, vol.16, issue.1, pp.5-13, 1972. ,
DOI : 10.1001/jama.1956.02960450020005
Functional MR Imaging of Prostate Cancer, RadioGraphics, vol.27, issue.1, pp.63-75, 2007. ,
DOI : 10.1148/rg.271065078
Recommandations pour la bonne pratique des biopsies prostatiques, Progr??s en Urologie, vol.21, issue.1, pp.18-28, 2011. ,
DOI : 10.1016/j.purol.2010.07.001
Mortality Results from a Randomized Prostate-Cancer Screening Trial, New England Journal of Medicine, vol.360, issue.13, pp.1310-1319, 2009. ,
DOI : 10.1056/NEJMoa0810696
Screening and Prostate-Cancer Mortality in a Randomized European Study, New England Journal of Medicine, vol.360, issue.13, pp.1320-1328, 2009. ,
DOI : 10.1056/NEJMoa0810084
Dépistage du cancer de la prostate: analyse critique des articles issus des études ERSPC et PLCO publiés en mars 2009. HAS 2010 Prostatic disorders: MR imaging at 1.5 T, Radiology, vol.12164, issue.2, pp.386-92, 1987. ,
The abnormal prostate: MR imaging at 1.5 T with histopathologic correlation., Radiology, vol.163, issue.2, pp.521-526, 1987. ,
DOI : 10.1148/radiology.163.2.2436253
Prostatic carcinoma: staging by clinical assessment, CT, and MR imaging., Radiology, vol.162, issue.2, pp.331-337, 1987. ,
DOI : 10.1148/radiology.162.2.3797645
Carcinoma of the prostate gland: MR imaging with pelvic phased-array coils versus integrated endorectal--pelvic phased-array coils., Radiology, vol.193, issue.3, pp.703-712, 1994. ,
DOI : 10.1148/radiology.193.3.7972810
Prostate Cancer: Relationships between Postbiopsy Hemorrhage and Tumor Detectability at MR Diagnosis, Radiology, vol.248, issue.2, pp.531-540, 2008. ,
DOI : 10.1148/radiol.2482070157
Imaging of organ-confined prostate cancer: functional ultrasound, MRI and PET/computed tomography, Current Opinion in Urology, vol.19, issue.2, pp.168-76, 2009. ,
DOI : 10.1097/MOU.0b013e328323f5ed
Multiparametric Magnetic Resonance Imaging of Prostate Cancer at 3T, Curr Opin Urol J Magn Reson Imaging, vol.150, issue.11, pp.71-7146, 2007. ,
DOI : 10.1016/j.juro.2006.08.007
Multiparametrische Magnetresonanztomografie der Prostata ??? Technik und klinische Anwendungen, R??Fo - Fortschritte auf dem Gebiet der R??ntgenstrahlen und der bildgebenden Verfahren, vol.183, issue.07, pp.607-617, 2011. ,
DOI : 10.1055/s-0029-1246055
Prostate Cancer: Body-Array versus Endorectal Coil MR Imaging at 3 T???Comparison of Image Quality, Localization, and Staging Performance, Radiology, vol.244, issue.1, pp.184-95, 2007. ,
DOI : 10.1148/radiol.2441060425
Does IVIM measure classical perfusion?, Magnetic Resonance in Medicine, vol.5, issue.3, pp.470-475, 1990. ,
DOI : 10.1161/01.RES.16.4.309
The capillary network: a link between ivim and classical perfusion, Magnetic Resonance in Medicine, vol.1, issue.1, pp.171-179, 1992. ,
DOI : 10.1148/radiology.178.2.1987621
URL : https://hal.archives-ouvertes.fr/hal-00350065
Biexponential characterization of prostate tissue water diffusion decay curves over an extended b-factor range, Magnetic Resonance Imaging, vol.24, issue.5, pp.563-571, 2006. ,
DOI : 10.1016/j.mri.2005.12.008
Diffusion MRI predicts transrectal ultrasound biopsy results in prostate cancer detection, Journal of Magnetic Resonance Imaging, vol.179, issue.Pt 1, pp.356-63, 2011. ,
DOI : 10.1016/j.juro.2008.01.017
Diffusion tensor imaging of prostate at 3 ,
High-resolution diffusion tensor imaging of prostate cancer using a reduced FOV technique, European Journal of Radiology, vol.80, issue.2, 2010. ,
DOI : 10.1016/j.ejrad.2010.06.038
Combined prostate diffusion tensor imaging and dynamic contrast enhanced MRI at 3T ??? quantitative correlation with biopsy, Magnetic Resonance Imaging, vol.28, issue.5, pp.621-629, 2010. ,
DOI : 10.1016/j.mri.2010.03.011
Magnetic resonance diffusion characteristics of histologically defined prostate cancer in humans, Magnetic Resonance in Medicine, vol.5, issue.4, pp.842-50, 2009. ,
DOI : 10.1148/radiology.179.3.2028002
ADC value and diffusion tensor imaging of prostate cancer: Changes in carbon-ion radiotherapy, Journal of Magnetic Resonance Imaging, vol.22, issue.suppl 2, pp.1331-1336, 2008. ,
DOI : 10.1148/radiology.201.3.8939209
Diffusion tensor imaging of the normal prostate at 3 Tesla, European Radiology, vol.61, issue.4, pp.716-737, 2008. ,
DOI : 10.1007/s00330-007-0795-7
Prostate cancer detection with 3 T MRI: Comparison of diffusion-weighted imaging and dynamic contrast-enhanced MRI in combination with T2-weighted imaging, Journal of Magnetic Resonance Imaging, vol.21, issue.3, pp.625-656, 2010. ,
DOI : 10.1148/radiology.202.3.9051019
R??le de l???IRM de diffusion pour la d??tection du cancer de la prostate avant ponction biopsie : ??tude multiparam??trique de 111 patients ?? 3 Tesla, Journal de Radiologie, vol.91, issue.11, pp.1121-1129, 2010. ,
DOI : 10.1016/S0221-0363(10)70157-8
Combined T2-weighted and diffusion-weighted MRI for localization of prostate cancer323-8. 36. Team RDC. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing Multiparametric MRI is helpful to predict tumor focality, stage, and size in patients diagnosed with unilateral low-risk prostate cancer Prostate Cancer Prostatic Dis, AJR Am J Roentgenol Austria Vienna, vol.1893, issue.2, 2007. ,
Usefulness of diffusion-weighted imaging and dynamic contrast-enhanced magnetic resonance imaging in the diagnosis of prostate transition-zone cancer, Acta Radiologica, vol.49, issue.10, pp.1207-1220, 2008. ,
DOI : 10.1080/02841850802508959
Usefulness of apparent diffusion coefficient map in diagnosing prostate carcinoma: Correlation with stepwise histopathology, Journal of Magnetic Resonance Imaging, vol.42, issue.1, pp.132-141, 2008. ,
DOI : 10.1148/radiology.195.2.7724756
MRI-guided prostate biopsy detects clinically significant cancer: analysis of a cohort of 100 patients after previous negative TRUS biopsy, World Journal of Urology, vol.15, issue.Suppl 1, 2011. ,
DOI : 10.1007/s00330-004-2458-2
Prostate cancer detection with 3-T MRI: Comparison of diffusion-weighted and T2-weighted imaging, European Journal of Radiology, vol.61, issue.2, pp.297-302, 2007. ,
DOI : 10.1016/j.ejrad.2006.10.002
Diffusion-weighted Endorectal MR Imaging at 3 T for Prostate Cancer: Tumor Detection and Assessment of Aggressiveness, Radiology, vol.259, issue.3, pp.775-84, 2011. ,
DOI : 10.1148/radiol.11102066
Assessment of Aggressiveness of Prostate Cancer: Correlation of Apparent Diffusion Coefficient With Histologic Grade After Radical Prostatectomy, American Journal of Roentgenology, vol.196, issue.2, pp.374-81, 2011. ,
DOI : 10.2214/AJR.10.4441
D'Amico Risk Stratification Correlates With Degree of Suspicion of Prostate Cancer on Multiparametric Magnetic Resonance Imaging, The Journal of Urology, vol.185, issue.3, pp.815-835, 2011. ,
DOI : 10.1016/j.juro.2010.10.076
Prostate cancer detection: the value of performing an MRI before a biopsy, Acta Radiologica, vol.50, issue.9, pp.1080-1088, 2009. ,
DOI : 10.3109/02841850903216718
Dynamic Contrast Enhanced, Pelvic Phased Array Magnetic Resonance Imaging of Localized Prostate Cancer for Predicting Tumor Volume: Correlation With Radical Prostatectomy Findings, The Journal of Urology, vol.176, issue.6, pp.2432-2439, 2006. ,
DOI : 10.1016/j.juro.2006.08.007
Evaluation of semi-quantitative dynamic contrast-enhanced MRI parameters for prostate cancer in correlation to whole-mount histopathology, European Journal of Radiology, vol.81, issue.3, 2011. ,
DOI : 10.1016/j.ejrad.2011.01.107
Angiogenesis imaging in the management of prostate cancer, Nature Clinical Practice Urology, vol.233, issue.12, pp.596-607, 2005. ,
DOI : 10.2214/ajr.178.1.1780097
Magnetic Resonance Imaging for the Detection, Localisation, and Characterisation of Prostate Cancer: Recommendations from a European Consensus Meeting, European Urology, vol.59, issue.4, pp.477-94, 2011. ,
DOI : 10.1016/j.eururo.2010.12.009
Thirty-Two-Channel Coil 3T Magnetic Resonance-Guided Biopsies of Prostate Tumor Suspicious Regions Identified on Multimodality 3T Magnetic Resonance Imaging: Technique and Feasibility, Investigative Radiology, vol.43, issue.10, pp.686-94, 2008. ,
DOI : 10.1097/RLI.0b013e31817d0506
Combined Multiparametric MRI and Targeted Biopsies Improve Anterior Prostate Cancer Detection, Staging, and Grading, Urology, vol.78, issue.6, 2011. ,
DOI : 10.1016/j.urology.2011.06.022
Diffusion-Weighted Imaging of the Prostate at 3 T for Differentiation of Malignant and Benign Tissue in Transition and Peripheral Zones, Journal of Computer Assisted Tomography, vol.31, issue.3, pp.449-54, 2007. ,
DOI : 10.1097/01.rct.0000243456.00437.59
Differentiation of noncancerous tissue and cancer lesions by apparent diffusion coefficient values in transition and peripheral zones of the prostate, Journal of Magnetic Resonance Imaging, vol.48, issue.3, pp.258-62, 2005. ,
DOI : 10.2214/ajr.170.2.9456953
Experience improves staging accuracy of endorectal magnetic resonance imaging in prostate cancer: what is the learning curve?, Can J Urol, vol.14, issue.1, pp.3429-3463, 2007. ,
Role of magnetic resonance imaging before initial biopsy: comparison of magnetic resonance imaging-targeted and systematic biopsy for significant prostate cancer detection, BJU International, vol.241, issue.8b, 2011. ,
DOI : 10.1148/radiol.2412051866
Areas Suspicious for Prostate Cancer: MR???guided Biopsy in Patients with at Least One Transrectal US-guided Biopsy with a Negative Finding???Multiparametric MR Imaging for Detection and Biopsy Planning, Radiology, vol.259, issue.1, pp.162-72, 2011. ,
DOI : 10.1148/radiol.10101251
Magnetic Resonance Imaging Guided Prostate Biopsy in Men With Repeat Negative Biopsies and Increased Prostate Specific Antigen, The Journal of Urology, vol.183, issue.2, pp.520-527, 2010. ,
DOI : 10.1016/j.juro.2009.10.022
???Prostatic evasive anterior tumours???: the role of magnetic resonance imaging, BJU International, vol.99, issue.9, pp.1231-1237, 2009. ,
DOI : 10.1016/S1078-1439(03)00031-0
Prostate needle biopsies: interobserver variation and clinical consequences of histopathological re-evaluation, APMIS, vol.103, issue.4-5, pp.4-5239, 2011. ,
DOI : 10.1111/j.1464-410X.2008.08255.x
Initial clinical experience with real-time transrectal ultrasonography-magnetic resonance imaging fusion-guided prostate biopsy, BJU International, vol.8752, issue.7, pp.841-846, 2008. ,
DOI : 10.1016/j.eururo.2006.03.007
Magnetic Resonance Imaging/Ultrasound Fusion Guided Prostate Biopsy Improves Cancer Detection Following Transrectal Ultrasound Biopsy and Correlates With Multiparametric Magnetic Resonance Imaging Advances in magnetic resonance imaging: how they are changing the management of prostate cancer, J Urol Eur Urol, vol.59, issue.6, pp.962-77, 2011. ,
Pathological Upgrading and Up Staging With Immediate Repeat Biopsy in Patients Eligible for Active Surveillance, The Journal of Urology, vol.180, issue.5, pp.1964-1971, 2008. ,
DOI : 10.1016/j.juro.2008.07.051
Changes in Prostate Cancer Grade on Serial Biopsy in Men Undergoing Active Surveillance, Journal of Clinical Oncology, vol.29, issue.20, pp.2795-800, 2011. ,
DOI : 10.1200/JCO.2010.33.0134
Clinical Results of Long-Term Follow-Up of a Large, Active Surveillance Cohort With Localized Prostate Cancer, Journal of Clinical Oncology, vol.28, issue.1, pp.126-157, 2010. ,
DOI : 10.1200/JCO.2009.24.2180
Diffusion-weighted magnetic resonance imaging for monitoring prostate cancer progression in patients managed by active surveillance, The British Journal of Radiology, vol.186, issue.997, pp.31-38, 2011. ,
DOI : 10.1001/jama.294.4.440
Real-Time Magnetic Resonance Imaging???Guided Focal Laser Therapy in Patients with Low-Risk Prostate Cancer, European Urology, vol.58, issue.1, pp.173-180, 2010. ,
DOI : 10.1016/j.eururo.2010.03.006
MR Imaging of Prostate after Treatment with High-Intensity Focused Ultrasound, Radiology, vol.246, issue.3, pp.833-877, 2008. ,
DOI : 10.1148/radiol.2463062080