Création d'une séquence consensus pour les gènes préS ,
nous avons présenté toutes les mutations différentes du consensus sur un même profil. Les mutations T57I et P62L sont responsables d'une diminution d'antigénicité prédite in silico ,
et pour des raisons techniques, il faut préciser que les séquençages ont été réalisés à partir de sérums recueillis à différents temps dans l'évolution de la maladie pour chaque patient. L'influence de la pression thérapeutique sur la séquence S doit être interprétée avec précautions ,
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