P. Nietert and R. Silver, Systemic sclerosis: environmental and occupational risk factors, Current Opinion in Rheumatology, vol.12, issue.6, pp.520-526, 2000.
DOI : 10.1097/00002281-200011000-00008

M. Bovenzi, F. Barbone, and F. Pisa, A case?control study of occupational exposures and systemic sclerosis, International Archives of Occupational and Environmental Health, vol.77, issue.1, pp.10-16, 2004.
DOI : 10.1007/s00420-003-0462-5

A. Maître, M. Hours, and V. Bonneterre, Systemic sclerosis and occupational risk factors: role of solvents and cleaning products, J Rheumatol. déc, vol.31, issue.12, pp.2395-401, 2004.

G. Mora, Systemic Sclerosis: Environmental Factors, The Journal of Rheumatology, vol.36, issue.11, pp.2383-96, 2009.
DOI : 10.3899/jrheum.090207

N. Dumoitier, S. Lofek, and L. Mouthon, Pathophysiology of systemic sclerosis: State of the art in 2014, La Presse M??dicale, vol.43, issue.10, pp.267-78, 2014.
DOI : 10.1016/j.lpm.2014.08.001

M. Elhai, J. Avouac, and A. Kahan, Systemic sclerosis: Recent insights, Joint Bone Spine, vol.82, issue.3, pp.148-53, 2015.
DOI : 10.1016/j.jbspin.2014.10.010

T. Hua-huy and A. Dinh-xuan, Cellular and molecular mechanisms in the pathophysiology of systemic sclerosis, Pathologie Biologie, vol.63, issue.2, pp.61-69, 2015.
DOI : 10.1016/j.patbio.2015.03.003

A. American-college and . Rheumatology, European League Against Rheumatism Collaborative Initiative, Arthritis Rheum, vol.65, issue.11, pp.2737-2784, 2013.

M. Cutolo, A. Sulli, and V. Smith, How to perform and interpret capillaroscopy, Best Practice & Research Clinical Rheumatology, vol.27, issue.2, pp.237-285, 2013.
DOI : 10.1016/j.berh.2013.03.001

M. Cutolo, A. Sulli, and C. Pizzorni, Nailfold videocapillaroscopy assessment of microvascular damage in systemic sclerosis, J Rheumatol, vol.27, issue.1, pp.155-60, 2000.

P. Clements, P. Lachenbruch, and J. Siebold, Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis, J Rheumatol, vol.22, issue.7, pp.1281-1286, 1995.

C. Denton, G. Lapadula, and L. Mouthon, Renal complications and scleroderma renal crisis, Rheumatology, vol.54, issue.suppl_3, pp.32-37, 2009.
DOI : 10.1002/art.22036

URL : https://academic.oup.com/rheumatology/article-pdf/48/suppl_3/iii32/18096299/ken483.pdf

P. De-groote, V. Gressin, and E. Hachulla, Evaluation of cardiac abnormalities by Doppler echocardiography in a large nationwide multicentric cohort of patients with systemic sclerosis, Annals of the Rheumatic Diseases, vol.67, issue.1, pp.31-37, 2008.
DOI : 10.1136/ard.2006.057760

C. Meune, J. Avouac, and K. Wahbi, Cardiac involvement in systemic sclerosis assessed by tissue-doppler echocardiography during routine care: A controlled study of 100 consecutive patients, Arthritis & Rheumatism, vol.23, issue.6, pp.1803-1812, 2008.
DOI : 10.7326/0003-4819-105-5-661

E. Jones, VALVULAR DISEASE OF THE HEART IN SYSTEMIC SCLERODERMA., British Journal of Dermatology, vol.17, issue.5, pp.183-90, 1962.
DOI : 10.1161/01.CIR.17.5.874

D. Angelo, W. Fries, J. Masi, and A. , Pathologic observations in systemic sclerosis (scleroderma)

M. Dewani, S. Qadri, and M. Lone, Progressive systemic sclerosis (scleroderma), carcinoma breast and valvular heart disease: an unusual combination, J Postgrad Med, vol.46, issue.3, pp.181-184, 2000.

Y. Emad, H. Sherbeni, and Y. Ragab, Arterial vasculopathy in systemic sclerosis: Computerized tomography (CT) angiographic features of macrovascular and microvascular upper limbs arteries, Joint Bone Spine, vol.81, issue.5, pp.433-440, 2014.
DOI : 10.1016/j.jbspin.2014.03.014

P. Youssef, T. Brama, and H. Englert, Limited scleroderma is associated with increased prevalence of macrovascular disease, J Rheumatol, vol.22, issue.3, pp.469-72, 1995.

D. Veale, T. Collidge, and J. Belch, Increased prevalence of symptomatic macrovascular disease in systemic sclerosis., Annals of the Rheumatic Diseases, vol.54, issue.10, pp.853-858, 1995.
DOI : 10.1136/ard.54.10.853

E. Dick, R. Aviv, and I. Francis, Catheter angiography and angioplasty in patients with scleroderma, The British Journal of Radiology, vol.74, issue.888, pp.1091-1097, 2001.
DOI : 10.1148/radiology.216.3.r00se25909

M. Ho, D. Veale, and C. Eastmond, Macrovascular disease and systemic sclerosis, Annals of the Rheumatic Diseases, vol.59, issue.1, pp.39-43, 2000.
DOI : 10.1136/ard.59.1.39

URL : http://ard.bmj.com/content/annrheumdis/59/1/39.full.pdf

G. Ngian, J. Sahhar, and I. Wicks, Arterial stiffness is increased in systemic sclerosis: a crosssectional comparison with matched controls, Clin Exp Rheumatol, vol.32, issue.6, 2014.

M. Akram, C. Handler, and M. Williams, Angiographically proven coronary artery disease in scleroderma, Rheumatology, vol.57, issue.11, pp.1395-1403, 2006.
DOI : 10.1136/ard.57.8.476

M. Mok, C. Lau, and S. Chiu, Systemic sclerosis is an independent risk factor for increased coronary artery calcium deposition, Arthritis & Rheumatism, vol.353, issue.Suppl 1, pp.1387-95, 2011.
DOI : 10.1056/NEJMsa050467

R. Montisci, A. Vacca, and P. Garau, Detection of early impairment of coronary flow reserve in patients with systemic sclerosis, Annals of the Rheumatic Diseases, vol.62, issue.9, pp.890-893, 2003.
DOI : 10.1136/ard.62.9.890

K. Au, M. Singh, and V. Bodukam, Atherosclerosis in systemic sclerosis: A systematic review and meta-analysis, Arthritis & Rheumatism, vol.40, issue.Suppl 2, pp.2078-90, 2011.
DOI : 10.1093/rheumatology/40.10.1102

P. Ungprasert, P. Charoenpong, and P. Ratanasrimetha, Risk of coronary artery disease in patients with systemic sclerosis: a systematic review and meta-analysis, Clinical Rheumatology, vol.131, issue.5???6, pp.1099-104, 2014.
DOI : 10.1111/j.1365-2141.2005.05753.x

D. Mukerjee, S. George, D. Coleiro, and B. , Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach, Annals of the Rheumatic Diseases, vol.62, issue.11, pp.1088-93, 2003.
DOI : 10.1136/ard.62.11.1088

N. Galiè, M. Humbert, and J. Vachiery, 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension, Eur Heart J, vol.317, 2015.

E. Hachulla, V. Gressin, and L. Guillevin, Early detection of pulmonary arterial hypertension in systemic sclerosis: A French nationwide prospective multicenter study, Arthritis & Rheumatism, vol.351, issue.12, pp.3792-800, 2005.
DOI : 10.1164/ajrccm.164.2.2006129

J. Coghlan, C. Denton, and E. Grünig, Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study, Annals of the Rheumatic Diseases, vol.65, issue.Suppl 1, pp.1340-1349, 2014.
DOI : 10.1002/art.37838

E. Diot, C. Valat, and E. Boissinot, Strategy for early diagnosis of lung involvement in systemic scleroderma], Rev Mal Respir, vol.17, issue.6, pp.1073-80, 2000.

L. Mouthon, A. Berezné, and . Brauner, Pneumopathie infiltrante diffuse de la scl??rodermie syst??mique, Revue des Maladies Respiratoires, vol.24, issue.8, pp.1035-1081, 2007.
DOI : 10.1016/S0761-8425(07)92767-9

M. Wagner, C. Chien, and K. , Imagerie des pneumopathies infiltratives diffuses chroniques en tomodensitom??trie??: du diagnostic ?? la quantification automatis??e, Revue des Maladies Respiratoires, vol.28, issue.10, pp.1207-1222, 2011.
DOI : 10.1016/j.rmr.2011.04.016

N. Goh, S. Desai, and S. Veeraraghavan, Interstitial Lung Disease in Systemic Sclerosis, American Journal of Respiratory and Critical Care Medicine, vol.177, issue.11, pp.1248-54, 2008.
DOI : 10.1164/ajrccm.164.7.2003140

J. Pope, Musculoskeletal involvement in scleroderma, Rheumatic Disease Clinics of North America, vol.29, issue.2, pp.391-408, 2003.
DOI : 10.1016/S0889-857X(03)00017-6

L. Montagna, G. Sodano, A. Capurro, and V. , The arthropathy of systemic sclerosis: a 12 month prospective clinical and imaging study, Skeletal Radiology, vol.10, issue.1, pp.35-41, 2005.
DOI : 10.7326/0003-4819-56-3-422

M. Baron, P. Lee, and E. Keystone, The articular manifestations of progressive systemic sclerosis (scleroderma)., Annals of the Rheumatic Diseases, vol.41, issue.2, pp.147-52, 1982.
DOI : 10.1136/ard.41.2.147

L. Catoggio, G. Evison, and J. Harkness, The arthropathy of systemic sclerosis (scleroderma)

G. Erre, A. Marongiu, and P. Fenu, The ???sclerodermic hand???: A radiological and clinical study, Joint Bone Spine, vol.75, issue.4, pp.426-457, 2008.
DOI : 10.1016/j.jbspin.2007.07.017

R. Misra, K. Darton, and R. Jewkes, ARTHRITIS IN SCLERODERMA, Rheumatology, vol.34, issue.9, pp.831-838, 1995.
DOI : 10.1093/rheumatology/34.9.831

F. Allali, L. Tahiri, and A. Senjari, Erosive Arthropathy in systemic sclerosis, BMC Public Health, vol.131, issue.3, p.260, 2007.
DOI : 10.2214/ajr.131.2.283

S. Koutaissoff, M. Vanthuyne, and V. Smith, Hand Radiological Damage in Systemic Sclerosis: Comparison with a Control Group and Clinical and Functional Correlations, Seminars in Arthritis and Rheumatism, vol.40, issue.5, pp.455-60, 2011.
DOI : 10.1016/j.semarthrit.2010.06.008

J. Avouac, H. Guerini, and J. Wipff, Radiological hand involvement in systemic sclerosis, Annals of the Rheumatic Diseases, vol.65, issue.8, pp.1088-92, 2006.
DOI : 10.1136/ard.2005.044602

A. Nitsche, Raynaud, Digital Ulcers and Calcinosis in Scleroderma, Reumatolog??a Cl??nica (English Edition), vol.8, issue.5, pp.270-277, 2012.
DOI : 10.1016/j.reumae.2012.08.001

T. Nakamura, K. Hirakawa, and H. Takaoka, Dystrophic calcinosis with both a huge calcified mass in the cervical spine and calcification in the chest wall in a patient with rheumatoid overlap syndrome, Clinical Rheumatology, vol.94, issue.5, 2014.
DOI : 10.1016/j.diii.2013.01.020

J. Bluett, C. Davies, and J. Harris, Cervical Spine Calcinosis in Systemic Sclerosis, The Journal of Rheumatology, vol.40, issue.9, pp.1617-1625, 2013.
DOI : 10.3899/jrheum.130089

A. Weerakoon, D. Sharp, and J. Chapman, Lumbar canal spinal stenosis due to axial skeletal calcinosis and heterotopic ossification in limited cutaneous systemic sclerosis: successful spinal decompression, Rheumatology, vol.12, issue.2, pp.2144-2150, 2011.
DOI : 10.5435/00124635-200403000-00007

A. Shoji, K. Tahara, and H. Hayashi, Severe headache complicated by vertical atlantoaxial subluxation in diffuse systemic sclerosis with crowned dens pattern calcification, Rheumatology International, vol.216, issue.1, pp.1247-50, 2011.
DOI : 10.1148/radiology.216.1.r00jl36213

C. Durant and D. Farge-bancel, Clinical images: Voluminous ectopic tumoral calcinosis of the spine in systemic sclerosis, Arthritis & Rheumatism, vol.63, issue.2, p.411, 2011.
DOI : 10.1002/art.27768

L. Bassett, K. Blocka, and D. Furst, Skeletal findings in progressive systemic sclerosis (scleroderma), American Journal of Roentgenology, vol.136, issue.6, pp.1121-1127, 1981.
DOI : 10.2214/ajr.136.6.1121

K. Olsen, E. Pike, and F. Chew, Progressive Systemic Sclerosis with Massive Paraspinal Soft-Tissue Calcinosis, American Journal of Roentgenology, vol.183, issue.3, p.634, 2004.
DOI : 10.2214/ajr.183.3.1830634

M. Ward, J. Curé, and S. Schabel, Symptomatic spinal calcinosis in systemic sclerosis (scleroderma), Arthritis & Rheumatism, vol.38, issue.10, pp.1892-1897, 1997.
DOI : 10.1097/00007632-199412000-00005

C. Manelfe, I. Catalaâ, and A. Sévely, Diagnosis: cervical vertebral calcinosis associated with systemic scleroderma], J Radiol, vol.80, issue.312, pp.1704-1710, 1999.

M. Arginteanu and N. Perin, Paraspinal calcinosis associated with progressive systemic sclerosis, Journal of Neurosurgery, vol.20, issue.5, pp.761-764, 1997.
DOI : 10.1007/BF00193097

D. Comi, A. Ferrara, and E. Valcamonica, Spinal calcinosis in systemic sclerosis: case report, Archivio di Ortopedia e Reumatologia, vol.23, issue.2-3, pp.2-347, 2011.
DOI : 10.1097/01.brs.0000229260.67357.53

A. Teng, M. Robbin, C. Furey, S. Easley, F. Karim et al., Tumoral Calcinosis in the Cervical Spine in a Patient with CREST Syndrome: A Case Report, JBJS Case Connector, vol.88, issue.1, pp.193-200, 2006.
DOI : 10.2106/JBJS.E.00536

S. Bracard, E. Thomas, and M. Braun, Cervical cord compression in scleroderma. One case, J Neuroradiol J Neuroradiol, vol.18, issue.1, pp.12-19, 1991.

S. Onishi, Y. Homma, H. Hasegawa, and M. Yasukawa, Multiple Tumoral Calcinosis in Systemic Sclerosis, Internal Medicine, vol.52, issue.23, p.2689, 2013.
DOI : 10.2169/internalmedicine.52.1291

S. Van-de-perre, F. Vanhoenacker, and B. Op-de-beeck, Paraspinal cervical calcifications associated with scleroderma, JBR-BTR Organe Société R Belge Radiol SRBR Orgaan Van K Belg Ver Voor Radiol KBVR, vol.86, issue.2, pp.80-82, 2003.

A. Daumas, A. Grob, and B. Faucher, Unusual cause of neck pain in systemic sclerosis]. Rev Médecine Interne Fondée Par Société Natl Francaise Médecine, Interne, vol.34, issue.11, pp.719-739, 2013.

T. Ogawa, T. Ogura, and N. Hayashi, Tumoral Calcinosis of Thoracic Spine Associated with Systemic Sclerosis, The Journal of Rheumatology, vol.36, issue.11, pp.2552-2555, 2009.
DOI : 10.3899/jrheum.090274

D. Giuggioli, F. Lumetti, and M. Colaci, Rituximab in the treatment of patients with systemic sclerosis. Our experience and review of the literature, Autoimmunity Reviews, vol.14, issue.11, pp.1072-1080, 2015.
DOI : 10.1016/j.autrev.2015.07.008

J. Avouac and Y. Allanore, Targeted immunotherapies in systemic sclerosis, Clin Exp Rheumatol, vol.32, issue.2, pp.165-72, 2014.

L. Scussel-lonzetti, F. Joyal, and J. Raynauld, Predicting Mortality in Systemic Sclerosis, Medicine, vol.81, issue.2, pp.154-67, 2002.
DOI : 10.1097/00005792-200203000-00005

Y. Allanore, J. Avouac, and A. Kahan, Systemic sclerosis, Nature Reviews Disease Primers, vol.75, issue.6, pp.650-655, 2008.
DOI : 10.1038/nrdp.2015.2

URL : https://hal.archives-ouvertes.fr/inserm-00827903

A. Servettaz, C. Agard, and M. Tamby, Physiopathologie de la scl??rodermie syst??mique: ??tat des lieux sur une affection aux multiples facettes, La Presse M??dicale, vol.35, issue.12, pp.1903-1918, 2006.
DOI : 10.1016/S0755-4982(06)74924-7

L. Mouthon, F. Rannou, and A. Bérezné, Patient preference disability questionnaire in systemic sclerosis: A cross???sectional survey, Arthritis & Rheumatism, vol.357, issue.7, pp.968-73, 2008.
DOI : 10.7326/0003-4819-133-8-200010170-00010

L. Scussel-lonzetti, F. Joyal, and J. Raynauld, Predicting Mortality in Systemic Sclerosis, Medicine, vol.81, issue.2, pp.154-67, 2002.
DOI : 10.1097/00005792-200203000-00005

Y. Allanore, J. Avouac, and A. Kahan, Systemic sclerosis, Nature Reviews Disease Primers, vol.75, issue.6, pp.650-655, 2008.
DOI : 10.1038/nrdp.2015.2

URL : https://hal.archives-ouvertes.fr/inserm-00827903

A. Tyndall, B. Bannert, and M. Vonk, Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database, Annals of the Rheumatic Diseases, vol.69, issue.10, pp.1809-1824, 2010.
DOI : 10.1136/ard.2009.114264

J. Pope, Survival is improving in systemic sclerosis: true or false?, Rheumatology, vol.49, issue.6, pp.959-61, 2012.
DOI : 10.1093/rheumatology/keq046

J. Pope, Musculoskeletal involvement in scleroderma, Rheumatic Disease Clinics of North America, vol.29, issue.2, pp.391-408, 2003.
DOI : 10.1016/S0889-857X(03)00017-6

L. Montagna, G. Sodano, A. Capurro, and V. , The arthropathy of systemic sclerosis: a 12 month prospective clinical and imaging study, Skeletal Radiology, vol.10, issue.1, pp.35-41, 2005.
DOI : 10.7326/0003-4819-56-3-422

M. Baron, P. Lee, and E. Keystone, The articular manifestations of progressive systemic sclerosis (scleroderma)., Annals of the Rheumatic Diseases, vol.41, issue.2, pp.147-52, 1982.
DOI : 10.1136/ard.41.2.147

L. Catoggio, G. Evison, and J. Harkness, The arthropathy of systemic sclerosis (scleroderma); comparison with mixed connective tissue disease, Clin Exp Rheumatol, vol.1, issue.2, pp.101-113, 1983.

G. Erre, A. Marongiu, and P. Fenu, The ???sclerodermic hand???: A radiological and clinical study, Joint Bone Spine, vol.75, issue.4, pp.426-457, 2008.
DOI : 10.1016/j.jbspin.2007.07.017

R. Misra, K. Darton, and R. Jewkes, ARTHRITIS IN SCLERODERMA, Rheumatology, vol.34, issue.9, pp.831-838, 1995.
DOI : 10.1093/rheumatology/34.9.831

D. Tuffanelli and R. Winkelmann, Systemic Scleroderma, Archives of Dermatology, vol.84, issue.3, pp.359-71, 1961.
DOI : 10.1001/archderm.1961.01580150005001

J. Avouac, H. Guerini, and J. Wipff, Radiological hand involvement in systemic sclerosis, Annals of the Rheumatic Diseases, vol.65, issue.8, pp.1088-92, 2006.
DOI : 10.1136/ard.2005.044602

A. Nitsche, Raynaud, Digital Ulcers and Calcinosis in Scleroderma, Reumatolog??a Cl??nica (English Edition), vol.8, issue.5, pp.270-277, 2012.
DOI : 10.1016/j.reumae.2012.08.001

J. Avouac, U. Walker, and E. Hachulla, Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study, Ann Rheum Dis, 2014205295.

M. Mok, C. Lau, and S. Chiu, Systemic sclerosis is an independent risk factor for increased coronary artery calcium deposition, Arthritis & Rheumatism, vol.353, issue.Suppl 1, pp.1387-95, 2011.
DOI : 10.1056/NEJMsa050467

V. Khurma, C. Meyer, and G. Park, A pilot study of subclinical coronary atherosclerosis in systemic sclerosis: Coronary artery calcification in cases and controls, Arthritis & Rheumatism, vol.181, issue.4, pp.591-598, 2008.
DOI : 10.2214/ajr.181.3.1810743

Y. Emad, H. Sherbeni, and Y. Ragab, Arterial vasculopathy in systemic sclerosis: Computerized tomography (CT) angiographic features of macrovascular and microvascular upper limbs arteries, Joint Bone Spine, vol.81, issue.5, pp.433-440, 2014.
DOI : 10.1016/j.jbspin.2014.03.014

G. Ngian, J. Sahhar, and I. Wicks, Arterial stiffness is increased in systemic sclerosis: a crosssectional comparison with matched controls, Clin Exp Rheumatol, vol.32, issue.6, pp.161-167, 2014.

D. Veale, T. Collidge, and J. Belch, Increased prevalence of symptomatic macrovascular disease in systemic sclerosis., Annals of the Rheumatic Diseases, vol.54, issue.10, pp.853-858, 1995.
DOI : 10.1136/ard.54.10.853

M. Ho, D. Veale, C. Eastmond, G. Nuki, and J. Belch, Macrovascular disease and systemic sclerosis, Annals of the Rheumatic Diseases, vol.59, issue.1, pp.39-43, 2000.
DOI : 10.1136/ard.59.1.39

URL : http://ard.bmj.com/content/annrheumdis/59/1/39.full.pdf

K. Au, M. Singh, and V. Bodukam, Atherosclerosis in systemic sclerosis: A systematic review and meta-analysis, Arthritis & Rheumatism, vol.40, issue.Suppl 2, pp.2078-90, 2011.
DOI : 10.1093/rheumatology/40.10.1102

P. Ungprasert, P. Charoenpong, and P. Ratanasrimetha, Risk of coronary artery disease in patients with systemic sclerosis: a systematic review and meta-analysis, Clinical Rheumatology, vol.131, issue.5???6, pp.1099-104, 2014.
DOI : 10.1111/j.1365-2141.2005.05753.x

N. Galiè, M. Humbert, and J. Vachiery, 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension, Eur Heart J, vol.317, 2015.

A. Agatston, W. Janowitz, and F. Hildner, Quantification of coronary artery calcium using ultrafast computed tomography, Journal of the American College of Cardiology, vol.15, issue.4, pp.827-859, 1990.
DOI : 10.1016/0735-1097(90)90282-T

S. Nagueh, C. Appleton, and T. Gillebert, Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography, Journal of the American Society of Echocardiography, vol.22, issue.2, pp.107-140, 2009.
DOI : 10.1016/j.echo.2008.11.023

E. Hachulla, V. Gressin, and L. Guillevin, Early detection of pulmonary arterial hypertension in systemic sclerosis: A French nationwide prospective multicenter study, Arthritis & Rheumatism, vol.351, issue.12, pp.3792-800, 2005.
DOI : 10.1164/ajrccm.164.2.2006129

M. Elhai, J. Avouac, A. Kahan, and Y. Allanore, Systemic sclerosis: Recent insights, Joint Bone Spine, vol.82, issue.3, pp.148-53, 2015.
DOI : 10.1016/j.jbspin.2014.10.010

D. Mukerjee, S. George, D. Coleiro, and B. , Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach, Annals of the Rheumatic Diseases, vol.62, issue.11, pp.1088-93, 2003.
DOI : 10.1136/ard.62.11.1088

C. Mihai, R. Landewé, and D. Van-der-heijde, Digital ulcers predict a worse disease course in patients with systemic sclerosis, Annals of the Rheumatic Diseases, vol.70, issue.(Suppl 2), 2015.
DOI : 10.1136/ard.2010.132431

F. Allali, L. Tahiri, and A. Senjari, Erosive Arthropathy in systemic sclerosis, BMC Public Health, vol.131, issue.3, p.260, 2007.
DOI : 10.2214/ajr.131.2.283

S. Koutaissoff, M. Vanthuyne, and V. Smith, Hand Radiological Damage in Systemic Sclerosis: Comparison with a Control Group and Clinical and Functional Correlations, Seminars in Arthritis and Rheumatism, vol.40, issue.5, pp.455-60, 2011.
DOI : 10.1016/j.semarthrit.2010.06.008

T. Ogawa, T. Ogura, and K. Ogawa, Paraspinal and intraspinal calcinosis: frequent complications in patients with systemic sclerosis, Annals of the Rheumatic Diseases, vol.68, issue.10, pp.1655-1661, 2009.
DOI : 10.1136/ard.2008.104216

E. Jones, VALVULAR DISEASE OF THE HEART IN SYSTEMIC SCLERODERMA., British Journal of Dermatology, vol.17, issue.5, pp.183-90, 1962.
DOI : 10.1161/01.CIR.17.5.874

D. Angelo, W. Fries, J. Masi, and A. , Pathologic observations in systemic sclerosis (scleroderma), The American Journal of Medicine, vol.46, issue.3, pp.428-468, 1969.
DOI : 10.1016/0002-9343(69)90044-8

M. Dewani, S. Qadri, and M. Lone, Progressive systemic sclerosis (scleroderma), carcinoma breast and valvular heart disease: an unusual combination, J Postgrad Med, vol.46, issue.3, pp.181-184, 2000.

A. Kahan and Y. Allanore, Primary myocardial involvement in systemic sclerosis, Rheumatology, vol.12, issue.8661, 2006.
DOI : 10.1016/j.euje.2004.12.006

S. Plastiras and S. Toumanidis, Systemic sclerosis: the heart of the matter, Hell J Cardiol HJC, vol.53, issue.4, pp.287-300, 2012.

M. Budoff and K. Gul, Expert review on coronary calcium, Vascular Health and Risk Management, vol.4, issue.2, pp.315-339, 2008.
DOI : 10.2147/VHRM.S1160

S. Wang, K. Yiu, and M. Mok, Prevalence and extent of calcification over aorta, coronary and carotid arteries in patients with rheumatoid arthritis, Journal of Internal Medicine, vol.283, issue.5, pp.445-52, 2009.
DOI : 10.1016/j.ejvs.2004.05.004

N. Wong, M. Sciammarella, and Y. Arad, Relation of thoracic aortic and aortic valve calcium to coronary artery calcium and risk assessment, The American Journal of Cardiology, vol.92, issue.8, pp.951-956, 2003.
DOI : 10.1016/S0002-9149(03)00976-7

A. Eisen, A. Tenenbaum, and N. Koren-morag, Calcification of the Thoracic Aorta as Detected by Spiral Computed Tomography Among Stable Angina Pectoris Patients: Association With Cardiovascular Events and Death, Circulation, vol.118, issue.13, pp.1328-1362, 2008.
DOI : 10.1161/CIRCULATIONAHA.107.712141

N. Wong, V. Lopez, and A. M. , Abdominal aortic calcium and multi-site atherosclerosis: The Multiethnic Study of Atherosclerosis, Atherosclerosis, vol.214, issue.2, pp.436-477, 2011.
DOI : 10.1016/j.atherosclerosis.2010.09.011

M. Chuang, R. Leslie, J. Massaro, E. Manders, C. Fox et al., Distribution of Abdominal Aortic Calcium by Computed Tomography, Academic Radiology, vol.20, issue.11, 2013.
DOI : 10.1016/j.acra.2013.08.008

J. Avouac and Y. Allanore, Targeted immunotherapies in systemic sclerosis, Clin Exp Rheumatol, vol.32, issue.2, pp.165-72, 2014.

D. Giuggioli, F. Lumetti, and M. Colaci, Rituximab in the treatment of patients with systemic sclerosis. Our experience and review of the literature, Autoimmunity Reviews, vol.14, issue.11, pp.1072-1080, 2015.
DOI : 10.1016/j.autrev.2015.07.008

S. Jordan, J. Distler, and B. Maurer, Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group, Annals of the Rheumatic Diseases, vol.66, issue.(Suppl 3), pp.1188-94, 2015.
DOI : 10.1136/ard.2006.066530