Antiseptique(s)-désinfectant(s)Concentration cytotoxique 50% ,
Cell culture infective dose 50%Concentration inhibitrice 50% ,
Ethylene diamine tetracetic acid ,
Human coronavirusHuman metapneumovirus ,
Herpes simplex virusMinimum essential medium, Infections liées aux soins ,
Bromure de 3-(4,5-diméthylthiazol-2-yl)-2,5-diphényl tétrazolium NCRNon coding region ,
Pan American Health Organization Américaine) ,
Severe acute respiratory syndrome associated coronavirus ,
10 -3 mol.L -1 ), elle n'avait pas atteint le seuil des 4 log 10 (Figure 30A) Elle ne pouvait donc pas, dans les conditions de l'essai ,
bien que très largement utilisée en médecine humaine, doit être utilisée avec une certaine précaution selon les risques infectieux en présence ,
cette molécule n'avait montré aucune cytotoxicité sur les cellules L-132, pour des temps de contact allant jusqu'à 168 h et des concentrations de 10 -3 mol.L -1 (Résultats, 3.2.1, p82) Ces résultats sont cohérents avec des travaux précédemment menés sur cette molécule au sein de notre équipe, 2003. ,
S-BTZ montrait effectivement une activité antivirale intéressante sur des virus enveloppés comme le HSV-1 et 2 (avec des CI 50 de l'ordre de 2.10 -5 mol.L -1 ) mais son activité à l'égard du PV-2 s'est avérée très faible, 2003. ,
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