I. La-coagulation-plasmatiqueannexe, 42 a. Initiation de la coagulation par le facteur tissulaire 42 b. Formation de la thrombine et amplification du processus, p.43

.. Phase-de-néovascularisation, 46 a. Un processus à étapes, p.47

.. Les-facteurs-de-croissance, 54 a. Le Platelet-Derived Growth Factor 55 b. Le Transforming Growth Factor ? 56 d. L'Hepatocyte Growth Factor, 57 e. L'Insulin-like Growth Factor ou somatomédine............. 57 f. L'Epithelial Growth Factor et le Platelet-Derived Endothelial Cell Growth Factor, p.57

D. S. Dohan-a, C. J. , D. A. , S. A. Girard-m-o, and D. D. , De l'usage des concentrés plaquettaires autologues en application topique Odontologie, 23-330-A-30, EMC, vol.16, p.2, 2005.

N. D. Position-de-la and P. Sfpio-sur-le, Société Française de Parodontologie et d'Implantologie Orale (SFPIO) [en ligne, p.2

V. W. Prp and . Therapy, Available at Wheeling Hospital: Steelers Hines Ward, Troy Polamalu Have Used Treatments. Wheeling Hospital [en ligne] https

. Press-release and . Point®, Platelet Rich Plasma : market snapshot. [en ligne] http://www.pressreleasepoint.com/platelet-rich-plasma-market-snapshot

S. A. Promising-treatment-for-ahletes and I. Blood, The New York Times, pp.17-19, 2009.

M. Re, C. Er, E. Rm, S. Sr, G. Strauss-je et al., Platelet Rich Plasma : Growth Factor enhancement for bone grafts. Oral Surgery Oral Medicine Oral Pathology Oral Radiology, pp.85-638, 1998.

S. D. , H. P. , and S. Dy, A simplified technique for producing Platelet Rich Plasma and Platelet concentrate for intraoral bone grafting techniques : a technical note, The International journal of oral & maxillofacial implants, vol.15, pp.879-882, 2000.

. Platextex®, Plateltex®prep Kit for the preparation of concentrated platelet-rich plasma (PRP) [en ligne

M. L. Balbo-v, C. E. , G. R. , and B. P. , Not every PRP-gel is born equal Evaluation of growth factor availability for tissues through four PRP-gel preparations: Fibrinet®, RegenPRP-Kit®, Plateltex® and one manual procedure, Vox Sanguinis, The International Journal of Transfusion Medicine, vol.97, pp.110-118, 2009.

. Médical-expo, Centrifugeuses pour plasmas riches en plaquettes. Le salon online de l'équipement médical

N. Mj, M. Mr, F. Fa, F. Se, G. Bosco-af et al., Effectiveness of two methods for preparation of autologous platelet-rich plasma: an experimental study in rabbits, European Journal of Dentistry, vol.4, issue.4, pp.395-402, 2010.

G. S. Mccusker, K. , S. T. , O. M. , G. A. et al., Clinical impact and biomaterial evaluation of autologous platelet gel in cardiac surgery, Perfusion, vol.23, issue.3, pp.179-186, 2008.

A. Tl, M. Pk, and F. Eg, Investigation of platelet-rich plasma in rabbit cranial defects: A pilot study, Journal of Oral Maxillofacial Surgery, vol.60, pp.1176-1181, 2002.

M. D. , P. H. , and W. Je, The Use of Autologous Platelet-Rich Plasma (Platelet Gel) and Autologous Platelet-Poor Plasma (Fibrin Glue) in Cosmetic Surgery, Plastic & Reconstructive Surgery, vol.107, issue.1, pp.229-237, 2001.

F. G. , K. E. Pereira-ruiz-mt, G. R. Vaccaro-f, D. Martino-a, C. A. et al., Platelet-rich plasma intra-articular injections for cartilage degeneration and osteoarthritis: single-versus double-spinning approach, Knee Surgery, Sports Traumatology, Arthroscopy, issue.10, pp.20-2082, 2012.

B. Davidson-en, . Van-der-kraam, . Pm, . Van-der, and . Berg-wb, TGF-?? and osteoarthritis, Osteoarthritis and Cartilage, vol.15, issue.6, pp.597-604, 2007.
DOI : 10.1016/j.joca.2007.02.005

D. Ehrenfest-dm, S. G. , S. J. , W. Hl, Z. Dr et al., Guidelines for the publication of articles related to platelet concentrates (Platelet- Rich Plasma -PRP, or Platelet-Rich Fibrin -PRF): the international classification of the POSEIDO

D. Ehrenfest-dm, A. I. , Z. Ma, Z. Cq, . Pinto-nr et al., Classification of platelet concentrates (Platelet-Rich Plasma-PRP, Platelet-Rich Fibrin-PRF) for topical and infiltrative use in orthopedic and sports medicine: current consensus, clinical implications and perspectives, Muscle, Ligaments and Tendons Journal, issue.1, pp.3-9, 2014.

M. Re, Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant dentistry, pp.225-228, 2001.

M. Re, Platelet-rich plasma: evidence to support its use. ournal of oral and maxillofacial surgery, pp.489-496, 2004.

M. L. Balbo-v, C. E. , and B. P. , Platelet-rich plasma and platelet gel preparation using Plateltex, Vox sanguinis, vol.94, issue.3, pp.202-208, 2008.

. Centre-de-biologie-et-médecine-du-sport-de-pau, Evidence based médecine et PRP, une mise au point en 2 parties Centre de biologie et médecine du sport de Pau [en ligne] http://www.medecinesportpau.fr/evidence-based-medecine-et-prp-une-mise-au-point-en-2-parties, p.2202

A. Mondiale-anti-dopage, Liste des interdictions 2013 Standard international Agence Mondiale Anti-dopage (AMA) [en ligne] https, p.2

A. Mondiale-anti-dopage, Liste des interdictions 2015 Standard international Agence Mondiale Anti-dopage (AMA) [en ligne] https

S. A. Khan-km, R. Cr, C. Jl, and D. V. , What do we mean by the term "inflammation"? A contemporary basic science update for sports medicine, British Journal of Sports Medicine, vol.38, issue.3, pp.372-380, 2004.

G. E. Projet-de-loi-relatif-À-la-bioéthique-n°3166, Assemblée Nationale

L. Loi, relative à la bioéthique. LEGIFRANCE Le service public de la diffusion du droit [en ligne] https, 2004.

E. Bioethique, Révision de la loi de bioéthique Contribution de l'AFSSAPS [en ligne

P. Ms, Angiogenèse et morphogenèse de l'arbre vasculaire : de la biologie cellulaire à la clinique, Médecine/sciences, pp.1378-138602, 2000.

L. Ug, L. M. , B. A. , S. F. , M. N. et al., Tissue Engineered Strategies for Skeletal Muscle Injury, Stem Cells International, vol.9, 2012.

A. Pr, C. Rbv, T. Mvt, D. Cruz-pacheco-i, C. Do-amaral-rjf et al., Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors, Stem Cells Research & Therapy, issue.43, p.67, 2013.

R. Gl, F. Ml, and P. J. , Molecular mechanisms of platelet exocytosis: insights into the " secrete " life of thrombocytes, Blood journal, issue.10, pp.3334-3342, 1996.

E. Tendinopathy, EPOCRATES An AthenaHealth Company [en ligne] https://online.epocrates.com/diseases

O. Nice, Epidémiologie des lésions tendineuses du membre inferieur chez le footballeur professionnel. OGC Nice club de football professionnel

Y. G. , R. Bb, and T. Rs, Tendon and Ligament Regeneration and Repair: Clinical Relevance and Developmental Paradigm. Birth defects research. Part C, Embryo today : reviews, Sept, vol.99, issue.3, pp.203-222, 2013.

M. Kk, B. V. , F. Fh, M. B. , and T. S. , Evaluation of the effects of platelet-rich plasma (PRP) therapy involved in the healing of sports-related soft tissue injuries

Z. J. , M. Kk, W. J. , F. Fh, and I. Hj, HGF mediates the anti-inflammatory effects of PRP on injured tendons, Public Library of Science one, vol.8, issue.6, p.67303, 2013.

L. Dn, K. K. , V. D. , P. A. , T. M. et al., The influence of Platelet-Rich Plasma on angiogenesis during the early phase of tendon healing, Foot & Ankle International, issue.11, pp.30-1101, 2009.

K. , B. M. , L. C. , O. C. , G. A. Sanchez-m et al., Reflections about the optimisation of the treatment of tendinopathies with PRP. Muscle, Ligaments and Tendons Journal, pp.1-4, 2015.

K. , D. P. , L. Goff-c, C. , and S. M. , Données scientifiques actuelles concernant le traitement par injection de concentré plaquettaire, p.2302

C. B. Niveau-de-preuve, Faculté de médecine TOULOUSE [en ligne, pp.20-20, 20102011.

H. Autorité and D. Santé, Etats des lieux Niveau de preuve et gradation des recommandations de bonne pratique. HAS [en ligne

. Prpinjections, Platelet Rich Plasma (PRP) Injections : Safety. Platelet Rich Plasma Injections The information resource website for PRP in Australia

W. Rj, P. R. , and T. Ma, Platelet-Rich Plasma as an effective treatment for proximal hamstring injuries, Orthopedics, vol.36, issue.1, pp.64-70, 2013.

J. S. , B. M. , and L. A. Bonnefoy-c, Apport des plasmas enrichis en plaquettes dans le traitement des lésions musculaires traumatiques ? Étude pilote à propos de 50 cas, Journal de Traumatologie du Sport, issue.1, pp.31-34, 2014.

B. G. , P. F. , P. Mf, P. F. De-filippo-m, V. Ma et al., Use of platelet-rich plasma in the care of sports injuries: our experience with ultrasound-guided injection, Blood Transfusion, vol.12, issue.1, pp.229-234, 2014.

. Chirurgiedusport and . Com, /Traitements-AUTRES-PRP- PRP___concentres_plaquettaires_Informations_sur_le_deroulement_de_la_seance-f-4-c-2338-sc- 108-a-760189, p.2302

M. Ea, G. Me, F. Neto-aa, A. Jh, . Bordalo-rodriguez-m et al., Platelet-Rich Plasma in rotator cuff repair : a prospective randomized study, The American Journal of Sports Medicine, issue.10, pp.42-2446, 2014.

J. Ch, S. Js, L. Yg, S. W. , K. H. et al., Platelet-Rich Plasma for arthroscopic repair of large to massive rotator cuff tears : a randomized, single-blind, parallel-group trial, The American Journal of Sports Medicine, issue.10, pp.41-2040, 2013.

G. T. , P. Jc, . Van-laar-w, . Den, and . Bl, Ongoing positive effect of Platelet-Rich Plasma versus corticosteroid injection in lateral epicondylitis. A double-blind randomized controlled trial with 2-year follow-up, The American Journal of Sports Medicine, 2011.

S. J. and S. Jl, Comparing PRP injections with ESWT for athletes with chronic patellar tendinopathy, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, issue.1, pp.88-89, 2014.

D. Vos-rj, W. A. Van-schie-ht, B. Sm, V. J. , W. H. et al., Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial, Journal of the American Medical Association, issue.2, pp.303-144, 2010.

K. E. and L. Jh, Autologous platelet-rich plasma versus dextrose prolotherapy for the treatment of chronic recalcitrant plantar fasciitis PM & R : the journal of injury, function, and rehabilitation, Feb, vol.6, issue.2, pp.152-158, 2014.

M. Rr, Platelet-rich plasma efficacy versus corticosteroid injection treatment for chronic severe plantar fasciitis, Foot & ankle international, vol.35, issue.4, pp.313-318, 2014.

B. M. , D. H. , B. I. , L. A. Bonnefoy-o, and L. T. , Prise en charge actuelle des tendinopathies d'Achille en 2015, p.2

P. Belgium-medical, Matériel médical et hospitalier, p.23

. Corpshumain and . Ca, Les muscles [en ligne

. Le-suivi-du-sportif, Focus sur la « tendinite » [en ligne] http://lesuividusportif.com/savoir-etcomprendre/focus-sur-la-tendinite

O. Du, P. De, . S. Faisant, . Une, C. Du et al., 64 FIGURE 44: IMPLICATION 68 FIGURE 49 69 FIGURE 50 12 TABLEAU II, FIGURE EVALUATION EVALUATION EVOLUTION STRUCTURE, vol.42, issue.9410?, pp.90-67

T. Etiologie, L. Facteurs, . Et-extrinseques-a-l-'origine, and T. De, 80 TABLEAU VIII, p.119

. Retirer, Fermer la seringue contenant le PPP à l'aide d'un bouchon luer-lock. La conserver éventuellement pour une utilisation future

. Le-concentré-de-prp-est-prêt-À-l-'emploi, Le cas échéant, fermer la seringue à l'aide du bouchon luer-lock. ü Classification des études selon le niveau de preuve scientifique

. Niveau-de-preuve, Cette capacité est jugée sur la correspondance de l'étude au cadre de travail (population, critères de jugement, question) et sur les caractéristiques suivantes : -adéquation du protocole d'étude à la question posée -existence ou non de biais importants dans la réalisation -adaptation de l'analyse statistique aux objectifs de l'étude -puissance de l'étude et en particulier taille de l'échantillon

D. Docteur-f-'i-ph-\rmacie-pr, !s.:nté par : ( l !LRE Sébasti..-n ~uj..:t : Le> Plasmas Riches en Plaquettes (PRPJ dnns le traitement lo-:al de? traumattsmes tcndino-musula1re

·. Juf-'l-@bullet-prcs1dcntc and . Mme, F\lVRE BC:atricc. Profc~scur Hématologie D1rcctm:c. \.1mc. I· i\IVIU Béatrice. Profe~,eur Hc:maiologie Jug~ 1\1 V IG!'-IEROl'< Claude, Profe.,eur èmcritc Hcmutolo~ie M PF.RRIN Julien. \1C'l.,-PH . Hclmatologic biologique 1\1. GEOFFROY Jean-Marc. Mèdc:cm du spon Vu et approu\o!, 1'\anc