. Une-Étude-similaire-À-celle-de-kikuiri, réalisée sur le porc, a montré les mêmes résultats. La cicatrisation muqueuse ayant été observée après 12 semaines et la reformation osseuse entre 12 semaines et 12 mois Ces deux études montrent que l'injection systémique de CSM permet la cicatrisation des sites d'ONM chez l'animal. Des études cliniques sur l'homme n

. La-pose-d, implants n'est pas contre-indiquée chez les patients traités par biphosphonates oraux pour une ostéoporose. Une évaluation rigoureuse pré chirurgicale de l'ensemble des facteurs de risque est nécessaire, p.97

. La-pose-d, implants est également possible chez les patients ayant une ostéoporose traitée par biphosphonates intra-veineux après la même évaluation des facteurs de risque. Cependant le patient devra être informé de l'absence de données concernant le risque associé à la pose d'implant chez ce type de patient, p.97

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