C. Legeay, C. Bourigault, D. Lepelletier, and J. R. Zahar, Prevention of healthcare-associated infections in neonates: room for improvement, Proceedings from the 9th Healthcare Infection Society International Conference9th Healthcare Infection Society International Conference, pp.319-323, 2015.
DOI : 10.1016/j.jhin.2015.02.003

L. Decembrino, A. Maini, N. Decembrino, I. Maggi, and S. Lacerenza, Management of outbreaks in neonatal intensive care units, Early Human Development, vol.90, pp.54-56, 2014.
DOI : 10.1016/S0378-3782(14)70018-0

C. L. Pessoa-silva, B. Meurer-moreira, V. Câmara-almeida, B. Flannery, M. C. Almeida-lins et al., Extended-spectrum ??-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit: risk factors for infection and colonization, Journal of Hospital Infection, vol.53, issue.3, pp.198-206, 2003.
DOI : 10.1053/jhin.2002.1373

A. J. Carey, L. Saiman, and R. A. Polin, Hospital-Acquired Infections in the NICU: Epidemiology for the New Millennium, Clinics in Perinatology, vol.35, issue.1, pp.223-249, 2008.
DOI : 10.1016/j.clp.2007.11.014

S. Kamath, S. Mallaya, and S. Shenoy, Nosocomial infections in neonatal intensive care units: Profile, risk factor assessment and antibiogram, The Indian Journal of Pediatrics, vol.37, issue.1, pp.37-39, 2010.
DOI : 10.1007/s12098-010-0005-5

P. Gastmeier, A. Loui, S. Stamm-balderjahn, S. Hansen, I. Zuschneid et al., Outbreaks in neonatal intensive care units???They are not like others, American Journal of Infection Control, vol.35, issue.3, pp.172-176, 2007.
DOI : 10.1016/j.ajic.2006.07.007

S. F. Levin and . Costa, Investigation of an outbreak of enterobacter cloacae in a neonatal unit and review of the literature, Journal of Hospital Infection, vol.70, issue.1, pp.7-14, 2008.

A. Gupta, Hospital-acquired infections in the neonatal intensive care unit-Klebsiella pneumoniae, Seminars in Perinatology, vol.26, issue.5, pp.340-345, 2002.
DOI : 10.1053/sper.2002.36267

R. Lin, B. Wu, X. F. Xu, X. C. Liu, H. Ye et al., Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae infection in a neonatal intensive care unit, World Journal of Pediatrics, vol.62, issue.3, pp.268-271, 2012.
DOI : 10.1016/j.jhin.2005.09.019

V. Rastogi, P. Nirwan, S. Jain, and A. Kapil, Nosocomial outbreak of septicaemia in neonatal intensive care unit due to extended spectrum ??-lactamase producing Klebsiella pneumoniae showing multiple mechanisms of drug resistance, Indian Journal of Medical Microbiology, vol.28, issue.4, pp.380-384, 2010.
DOI : 10.4103/0255-0857.71834

K. Nakamura, M. Kaneko, Y. Abe, N. Yamamoto, H. Mori et al., Outbreak of extended-spectrum ??-lactamase-producing Escherichia coli transmitted through breast milk sharing in a neonatal intensive care unit, Multi-drug Resistant Gram Negative Bacteria, pp.42-46, 2016.
DOI : 10.1016/j.jhin.2015.05.002

D. Engur, B. Cetinkaya-cakmak, M. Kaynak-turkmen, M. Telli, M. Eyigor et al., in a Neonatal Intensive Care Unit, Breastfeeding Medicine, vol.9, issue.10, pp.551-554, 2014.
DOI : 10.1089/bfm.2014.0054

C. Sánchez-carrillo, B. Padilla, M. Marín, M. Rivera, E. Cercenado et al., Contaminated feeding bottles: The source of an outbreak of Pseudomonas aeruginosa infections in a neonatal intensive care unit, Hemodynamic Monitoring in the Diagnosis and Management of Heart Failure, pp.150-154, 2009.
DOI : 10.1016/j.ajic.2008.04.259

R. Zheng, Q. Zhang, Y. Guo, Y. Feng, L. Liu et al., Outbreak of plasmidmediated ndm-1-producing klebsiella pneumoniae st105 among neonatal patients in yunnan, china, Annals of clinical microbiology and antimicrobials, vol.15, issue.1, p.1, 2016.

C. Casolari, M. Pecorari, E. Della-casa, S. Cattani, C. Venturelli et al., Serratia marcescens in a neonatal intensive care unit : two long-term multiclone outbreaks in a 10-year observational study, New Microbiologica, vol.36, issue.4, pp.373-383, 2013.

H. Yapicioglu, T. G. Gokmen, D. Yildizdas, F. Koksal, F. Ozlu et al., Pseudomonas aeruginosa infections due to electronic faucets in a neonatal intensive care unit, Journal of Paediatrics and Child Health, vol.57, issue.5, pp.48430-434, 2012.
DOI : 10.1093/tropej/fmq060

T. A. Madani, S. Alsaedi, L. James, B. S. Eldeek, A. A. Jiman-fatani et al., Serratia marcescens-contaminated baby shampoo causing an outbreak among newborns at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, Journal of Hospital Infection, vol.78, issue.1, pp.16-19, 2011.
DOI : 10.1016/j.jhin.2010.12.017

M. Cormier and A. Jolivet-gougeon, Outbreak of serratia marcescens in a neonatal intensive care unit : contaminated unmedicated liquid soap and risk factors, Journal of Hospital Infection, vol.72, issue.1, pp.17-22, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00911503

A. Khajuria, A. Praharaj, M. Kumar, N. Grover, and A. Aggarwal, Multidrug resistant ndm-1 metallo-betalactamase producing klebsiella pneumoniae sepsis outbreak in a neonatal intensive care unit in a tertiary care center at central india, Indian Journal of Pathology and Microbiology, 2014.

N. Pestourie, F. Garnier, O. Barraud, A. Bedu, M. C. Ploy et al., Outbreak of AmpC ??-lactamase-hyper-producing Enterobacter cloacae in a neonatal intensive care unit in a French teaching hospital, American Journal of Infection Control, vol.42, issue.4, pp.456-458, 2014.
DOI : 10.1016/j.ajic.2013.11.005

T. M. Macdonald, J. M. Langley, T. Mailman, K. Allain, G. Nelson et al., Serratia marcescens outbreak in a neonatal intensive care unit related to the exit port of an oscillator, Pediatric Critical Care Medicine, vol.12, issue.6, pp.282-286, 2011.
DOI : 10.1097/PCC.0b013e31820ac42a

U. Arslan, I. Erayman, S. Kirdar, S. Yuksekkaya, O. Cimen et al., sepsis outbreak in a neonatal intensive care unit, Pediatrics International, vol.5, issue.2, pp.208-212, 2010.
DOI : 10.1017/S0195941700060872

G. Fabbri, M. Panico, L. Dallolio, R. Suzzi, M. Ciccia et al., Outbreak of Ampicillin/Piperacillin-Resistant Klebsiella Pneumoniae in a Neonatal Intensive Care Unit (NICU): Investigation and Control Measures, International Journal of Environmental Research and Public Health, vol.23, issue.3, pp.808-815, 2013.
DOI : 10.1086/503164

S. A. Narayan, J. L. Kool, M. Vakololoma, A. C. Steer, A. Mejia et al., Investigation and Control of an Outbreak of Enterobacter aerogenes Bloodstream Infection in a Neonatal Intensive Care Unit in Fiji, Infection Control & Hospital Epidemiology, vol.19, issue.08, pp.797-800, 2009.
DOI : 10.1136/adc.2002.022863

C. A. Oliveira, R. E. Viana, and Q. S. Damasceno, Contamination of hospital mattresses by microorganisms of epidemiological relevance : an integrative review, Journal of Nursing UFPE on line, vol.7, issue.1, pp.236-245, 2012.

M. Yu, K. Cross, A. Petrich, and J. Fish, Crib Mattress Investigation: A quality improvement study to assess mattress cover permeability and bacterial growth in crib mattresses, American Journal of Infection Control, vol.44, issue.7, pp.837-839, 2016.
DOI : 10.1016/j.ajic.2015.12.014

U. Food and D. Administration, Damaged or worn covers for medical bed mattresses pose risk of contamination and patient infection : Fda safety communication, 2014.

S. L. Bradbury, D. Mack, T. Crofts, and R. T. Ellison, Potential bloodborne pathogen exposure from occult mattress damage, American Journal of Infection Control, vol.42, issue.4, pp.421-422, 2014.
DOI : 10.1016/j.ajic.2013.10.011

Y. Golan, S. Doron, B. Sullivan, and D. R. Snydman, Transmission of vancomycin-resistant enterococcus in a neonatal intensive care unit. The Pediatric infectious disease journal, pp.566-567, 2005.

S. Durand, A. Rideau-batista-novais, R. Mesnage, C. Combes, M. N. Didelot et al., Validation of nosocomial infection in neonatology: A new method for standardized surveillance, American Journal of Infection Control, vol.42, issue.8, pp.42861-864, 2014.
DOI : 10.1016/j.ajic.2014.04.021

C. Dupont, A. L. Michon, E. Jumas-bilak, N. Norskov-lauritsen, R. Chiron et al., Intrapatient diversity of Achromobacter spp. involved in chronic colonization of Cystic Fibrosis airways, Infection, Genetics and Evolution, vol.32, pp.214-223, 2015.
DOI : 10.1016/j.meegid.2015.03.012

A. Gouby, C. Neuwirth, G. Bourg, N. Bouziges, M. J. Carles-nurit et al., Epidemiological study by pulsed-field gel electrophoresis of an outbreak of extended-spectrum beta-lactamase-producing klebsiella pneumoniae in a geriatric hospital, Journal of Clinical Microbiology, vol.32, issue.2, pp.301-305, 1994.

B. Brooks, B. A. Firek, C. S. Mille, I. Sharon, B. C. Thomas et al., Microbes in the neonatal intensive care unit resemble those found in the gut of premature infants, Microbiome, vol.2, issue.1, pp.1-16, 2014.
DOI : 10.1016/j.jhin.2011.06.008

M. S. Cilieborg, M. Boye, and P. T. Sangild, Bacterial colonization and gut development in preterm neonates, 3rd International Conference on, pp.41-49, 2012.
DOI : 10.1016/j.earlhumdev.2011.12.027

L. E. Hartz, W. Bradshaw, and D. H. Brandon, Potential NICU Environmental Influences on the Neonate??s Microbiome, Advances in Neonatal Care, vol.15, issue.5, pp.324-335, 2015.
DOI : 10.1097/ANC.0000000000000220

L. A. Denkel, F. Schwab, A. Kola, R. Leistner, L. Garten et al., The mother as most important risk factor for colonization of very low birth weight (VLBW) infants with extended-spectrum ??-lactamase-producing Enterobacteriaceae (ESBL-E), Journal of Antimicrobial Chemotherapy, vol.45, issue.2, pp.692230-2237, 2014.
DOI : 10.1046/j.1442-200X.2003.01719.x

T. Hendrik, A. F. Voor, and M. C. Vos, Clinical and molecular epidemiology of extended-spectrum betalactamase-producing klebsiella spp. : A systematic review and meta-analyses, PloS one, issue.10, pp.10-0140754, 2015.

C. I. Gallimore, C. Taylor, A. R. Gennery, A. J. Cant, A. Galloway et al., Contamination of the Hospital Environment with Gastroenteric Viruses: Comparison of Two Pediatric Wards over a Winter Season, Journal of Clinical Microbiology, vol.46, issue.9, pp.3112-3115, 2008.
DOI : 10.1128/JCM.00400-08

S. J. Dancer, Controlling Hospital-Acquired Infection: Focus on the Role of the Environment and New Technologies for Decontamination, Clinical Microbiology Reviews, vol.27, issue.4, pp.665-690, 2014.
DOI : 10.1016/j.ajic.2013.05.014

B. Clarivet, D. Grau, E. Jumas-bilak, H. Jean-pierre, A. Pantel et al., Persisting transmission of carbapenemase-producing klebsiella pneumoniae due to an environmental reservoir in a university hospital , france, Euro surveillance : bulletin Européen sur les maladies transmissibles= European communicable disease bulletin, p.2016, 2012.

S. Romano-bertrand, A. Filleron, R. Mesnage, A. Lotthé, M. N. Didelot et al., Staphylococcus aureus in a neonatal care center: methicillin-susceptible strains should be a main concern, Antimicrobial Resistance and Infection Control, vol.3, issue.1, pp.1-9, 2014.
DOI : 10.1186/2047-2994-3-21

I. K. Hosein, P. N. Hoffman, S. Ellam, T. M. Asseez, A. Fakokunde et al., Summertime Bacillus cereus colonization of hospital newborns traced to contaminated, laundered linen, Journal of Hospital Infection, vol.85, issue.2, pp.149-154, 2013.
DOI : 10.1016/j.jhin.2013.06.001

M. Butin, P. Martins-simoes, J. C. Picaud, A. Kearns, O. Claris et al., Adaptation to vancomycin pressure of multiresistant staphylococcus capitis nrcs-a involved in neonatal sepsis, Journal of Antimicrobial Chemotherapy, issue.11, pp.703027-3031, 2015.

M. C. De-goffau, K. A. Bergman, H. J. De-vries, N. E. Meessen, J. E. Degener et al., ABSTRACT, Applied and Environmental Microbiology, vol.77, issue.24, pp.778568-8572, 2011.
DOI : 10.1128/AEM.06015-11

E. Creamer and H. Humphreys, The contribution of beds to healthcare-associated infection: the importance of adequate decontamination, Journal of Hospital Infection, vol.69, issue.1, pp.8-23, 2008.
DOI : 10.1016/j.jhin.2008.01.014

C. Braux, A. Lagier, M. C. Passet-gros, S. Ducki, J. Shum et al., Entretien des incubateurs de néonatalogiè a l, XVI, issue.3, 2008.

C. Sud-est, L'entretien des incubateurs en service de néonatologie, Fédération nationale des pédiatres néonatologues, CCLIN Sud-Est, 2010.

J. D. Sexton, B. D. Tanner, S. L. Maxwell, and C. P. Gerba, Reduction in the microbial load on high-touch surfaces in hospital rooms by treatment with a portable saturated steam vapor disinfection system, American Journal of Infection Control, vol.39, issue.8, pp.39655-662, 2011.
DOI : 10.1016/j.ajic.2010.11.009

B. D. Tanner, Reduction in infection risk through treatment of microbially contaminated surfaces with a novel, portable, saturated steam vapor disinfection system, American Journal of Infection Control, vol.37, issue.1, pp.20-27, 2009.
DOI : 10.1016/j.ajic.2008.03.008

O. Meunier, C. Meistermann, and A. Schwebel, Efficacit?? et limites des nettoyeurs vapeurs en milieu hospitalier, Pathologie Biologie, vol.57, issue.3, pp.252-257, 2009.
DOI : 10.1016/j.patbio.2007.12.004

C. J. Griffith and S. J. Dancer, Hospital cleaning: problems with steam cleaning and microfibre, Journal of Hospital Infection, vol.72, issue.4, pp.360-361, 2009.
DOI : 10.1016/j.jhin.2009.04.009

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