Le rapport médical et scientifique du prélèvement et de la greffe en France, 2011. ,
Rapport annuel 2012 de l'Agence de la biomédecine, 2012. ,
Réponse immunitaire de type cellulaire -Activation des lymphocytes T. Les bases de l'immunologie fondamentale et clinique, pp.81-102 ,
Mode d'action des immunosuppresseurs et leurs complications ,
Antibody-mediated vascular rejection of kidney allografts: a population-based study, The Lancet, vol.381, issue.9863, pp.313-319, 2013. ,
DOI : 10.1016/S0140-6736(12)61265-3
Infection in Solid-Organ Transplant Recipients, New England Journal of Medicine, vol.357, issue.25, pp.2601-2614, 2007. ,
DOI : 10.1056/NEJMra064928
Viral Infection in the Renal Transplant Recipient, Journal of the American Society of Nephrology, vol.16, issue.6, pp.1758-1774, 2005. ,
DOI : 10.1681/ASN.2004121113
Incidence, Clinical Characteristics and Risk Factors of Late Infection in Solid Organ Transplant Recipients: Data from the RESITRA Study Group, :964?971. 10. Crough T, Khanna R. Immunobiology of human cytomegalovirus: from bench to bedside, 2007. ,
DOI : 10.1097/00007890-200205270-00013
Seroprevalence to cytomegalovirus in the Portuguese population, Euro Surveill, vol.16, 2002. ,
Cytomegalovirus Seroprevalence in the United States: The National Health and Nutrition Examination Surveys, 1988???2004, Clinical Infectious Diseases, vol.50, issue.11, pp.1439-1447, 1988. ,
DOI : 10.1086/652438
The risk of cytomegalovirus recurrence after kidney transplantation International consensus guidelines on the management of cytomegalovirus in solid organ transplantation Extended valganciclovir prophylaxis in D+/R-kidney transplant recipients is associated with long-term reduction in cytomegalovirus disease: two-year results of the IMPACT study Valacyclovir prophylaxis versus preemptive valganciclovir therapy to prevent cytomegalovirus disease after renal transplantation, Transpl Int. déc Transplantation. avr Transplantation. déc Am J Transplant. janv, vol.2489908, pp.1427-1431, 2008. ,
Valganciclovir prophylaxis versus preemptive therapy in cytomegalovirus-positive renal allograft recipients, Transplantation ,
DOI : 10.1097/TP.0000000000002024
Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects Functional signatures of protective antiviral T-cell immunity in human virus infections Van de Berg PJEJ, van Stijn A, Ten Berge IJM, van Lier RAW. A fingerprint left by cytomegalovirus infection in the human T cell compartment Predominant type 1 CMV-specific memory T-helper response in humans: evidence for gender differences in cytokine secretion, Transplantation. janv J Exp Med. sept Immunol Rev. juin J Clin Virol. mars Villacres MC Hum Immunol. mai, vol.932022114165, issue.20, pp.61-68, 2004. ,
Phenotype and function of human T lymphocyte subsets: consensus and issues. Cytom A Expanding roles for CD4 + T cells in immunity to viruses, nov Nat Rev Immunol. févr, vol.7312, pp.136-148, 2008. ,
A human memory T cell subset with stem cell-like properties1290?1297. 26. Pantaleo G, Harari A. Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases, Nat Med. oct Nat Rev Immunol. mai, vol.176, pp.417-423, 2006. ,
Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for cytomegalovirus-specific CD8+ T cells Virologic and immunologic monitoring of cytomegalovirus to guide preemptive therapy in solid-organ transplantation, J Immunol. oct Am J Transplant. nov, vol.18911, pp.2463-2471, 2011. ,
Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells High levels of CMV-IE-1- specific memory T cells are associated with less alloimmunity and improved renal allograft function, J Exp Med. avr Transpl Immunol. mars, vol.20120, 2005. ,
The Western Europe Cohort of Kidney Transplanted Recipients-The DIVAT Network. 33 Evaluating cellular polyfunctionality with a novel polyfunctionality index, PloS One. Béné MC, vol.7, issue.34, 2012. ,
Premature aging of circulating T cells in patients with end-stage renal disease Progressive loss of renal function is associated with activation and depletion of naive T lymphocytes The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age Expansion of cytolytic CD4+CD28-T cells in end-stage renal disease Cyclosporin A and tacrolimus reduce T-cell polyfunctionality but not interferon-? responses directed at cytomegalovirus, Automated cell count in flow cytometry: a valuable tool to assess CD4 absolute levels in peripheral blood408?413. 40. Havenith SHC, Yong SL, van Donselaar-van der Pant KAMI, van Lier RAW, ten Berge IJM, Bemelman FJ. Everolimus-treated renal transplant recipients have a more robust CMVspecific CD8+ T-cell response compared with cyclosporine-or mycophenolate-treated patients. Transplantation. 15 janv, pp.208-217, 1998. ,
Receveurs séropositifs pour le CMV avec réactivation virale ; No Réact : Receveurs séropositifs pour le CMV sans réactivation virale ; TN : Lymphocytes T naïfs ,