.. Réactions-utilisant-un-antigène-soluble, 46 b.1 L'hémagglutination passive = indirecte, Enzyme Linkeg Immuno Sorbent Assay), p.47

B. Le-diagnostic, 60 a.1 L'inoculation à l'animal, La PCR, vol.61, p.62

.. Le-suivi-de-la-grossesse, 63 b.1 Absence d'infection foetale lors de l'amniocentèse 63 b.2 Présence d'une infection foetale, p.63

N. Le-diagnostic, 64 4.2.2.2 L'imagerie cérébrale, 66 b.2 Le western blot, p.67

N. Traitement-post, 74 5.2.2.1 Conduite à tenir chez un nourrisson issu d'une mère ayant présenté une séroconversion toxoplasmique en cours de grossesse, p.75

D. Ajzenberg, L. Balnus, A. Dumetre, M. Demar, B. Carme et al., Genetic diversity, clonality and sexuality in Toxoplasma gondii, International Journal for Parasitology, vol.34, issue.10, pp.1185-96, 2004.
DOI : 10.1016/j.ijpara.2004.06.007

B. Carme, La toxoplasmose chez la femme enceinte en France en 1995, BEH, p.51, 1996.

A. Antsaklis and D. Daskalakis, Prenatal diagnosis of congenital toxoplasmosis, Prenatal Diagnosis, vol.18, issue.12, pp.1107-1118, 2002.
DOI : 10.1093/clinids/18.6.853

F. G. Araujo, Azithromycin, a macrolide antibiotic with potent activity against Toxoplasma gondii., Antimicrobial Agents and Chemotherapy, vol.32, issue.5, pp.755-757, 1988.
DOI : 10.1128/AAC.32.5.755

L. Baril, T. Ancelle, P. Thulliez, V. Tirard-fleury, and B. Carme, Facteurs de risque d'acquisition de l'homme, Med Mal Infect, vol.23, pp.129-138

M. H. Bessières, C. Roques, A. Berrebi, V. Barre, M. Cazaux et al., IgA antibody response during acquired and congenital toxoplasmosis., Journal of Clinical Pathology, vol.45, issue.7, pp.605-613, 1992.
DOI : 10.1136/jcp.45.7.605

M. H. Bessières, A. Berrebi, M. Rolland, M. C. Bloom, C. Roques et al., Neonatal screening for congenital toxoplasmosis in a cohort of 165 women infected during pregnancy and influence of in utero treatment on the results of neonatal tests, European Journal of Obstetrics & Gynecology and Reproductive Biology, vol.94, issue.1
DOI : 10.1016/S0301-2115(00)00300-6

M. W. Black and J. C. Boothroyd, Lytic Cycle of Toxoplasma gondii, Microbiology and Molecular Biology Reviews, vol.64, issue.3, pp.607-630, 2000.
DOI : 10.1128/MMBR.64.3.607-623.2000

A. Bonhomme, L. Pingret, and J. M. Pinon, Toxoplasma gondii cellular invasion. Parasitologia, pp.31-43, 1992.

A. P. Brezin and P. Thulliez, Ophthalmic outcomes after prenatal and postnatal treatment of congenital toxoplasmosis, American Journal of Ophthalmology, vol.135, issue.6, pp.779-84, 2003.
DOI : 10.1016/S0002-9394(02)01704-X

J. Galama, Effectiveness of spiramycin for treatment of congenital Toxoplasma gondii infection in rhesus monkeys, Antimicrob Agents Chemother, vol.38, pp.1930-1936, 1994.

J. Cazenave, F. Forestier, M. H. Bessieres, B. Broussin, and J. Begueret, Contribution of a New PCR assay to the prenatal diagnosis of congenital toxoplasmosis, Prenatal Diagnosis, vol.6, issue.2, pp.119-146, 1992.
DOI : 10.1002/pd.1970120207

M. L. Chiappino, B. A. Nichols, and G. R. O-'connor, Scanning electron microscopy of Toxoplasma gondii : parasite torsion and host-cell responses during invasion, Journal of Parasitology, vol.31, issue.2, pp.288-292, 1984.

B. Cimon, P. Penn, S. Brun, and D. Chabasse, Comment résoudre les difficultés du sérodiagnostic de la toxoplasmose chez la femme enceinte ? Immuno-analyse et Biologie spécialisée, pp.143-147, 2002.
DOI : 10.1016/s0923-2532(02)01183-3

J. Couvreur and G. Desmonts, A homogeneous series of 210 cases of congénital toxoplasmosis in 0 to 11 month-old infants detected prospectively, Ann Pediatr, issue.10, pp.31-815, 1984.

J. Couvreur, G. Desmonts, and P. Thulliez, Prophylaxis of congenital toxoplasmosis. Effects of spiramycin on placental infection, Journal of Antimicrobial Chemotherapy, vol.22, issue.Supplement_B, pp.193-200, 1988.
DOI : 10.1093/jac/22.Supplement_B.193

J. Couvreur and . Toxoplasmose-congénital, Toxoplasmose cong??nitale. Prise en charge et devenir, M??decine et Maladies Infectieuses, vol.23, pp.176-182, 1993.
DOI : 10.1016/S0399-077X(05)80619-5

J. Couvreur, Le problème de la toxoplasmose congénitale : l'évolution sur quatre décennies

F. Daffos, F. Forestier, M. Capella-pavlovsky, P. Thulliez, C. Aufrant et al., Prenatal Management of 746 Pregnancies at Risk for Congenital Toxoplasmosis, New England Journal of Medicine, vol.318, issue.5, pp.271-276, 1988.
DOI : 10.1056/NEJM198802043180502

B. R. Dannemann, W. C. Vaughan, P. Thulliez, and J. S. Remington, Differential agglutination test for diagnosis of recently acquired infection with Toxoplasma gondii, J Clin Microbiol, vol.28, issue.9, pp.1928-1961, 1990.

F. Derouin, M. C. Mazeron, and J. P. Garin, Comparative study of tissue culture and mouse inoculation methods for demonstration of Toxoplasma gondii, J. Clin Microbiol, vol.25, pp.1597-600, 1987.

F. Derouin and C. Chastang, In vitro effects of folate inhibitors on Toxoplasma gondii., Antimicrobial Agents and Chemotherapy, vol.33, issue.10
DOI : 10.1128/AAC.33.10.1753

F. Derouin and P. Thulliez, Diagnostic biologique de la toxoplasmose, Laborama, vol.33, pp.5-17, 1993.

F. Derouin, Drug effective against Toxoplasma gondii .Present statue and future. In congenital toxoplasmosis, Antimicrob Agents Chemother, pp.95-110, 1999.

F. Derouin, La toxoplasmose chez l'homme: diagnostic, prévention et traitement, p.35, 2002.

G. Desmonts, J. Couvreur, F. Alison, J. Baudelot, J. Gerbeau et al., Etude épidémiologique sur la toxoplasmose : de l'influence de la cuisson des viandes de boucherie sur la fréquence de l'infection humaine, Rev. Fr. Etud. Clin. Biol, vol.10, pp.952-958, 1965.

G. Desmonts and Y. Naot, Immunoglobulin M-immunosorbent agglutination assay for diagnosis of infectious diseases: diagnosis of acute congenital and acquired Toxoplasma infections, J

G. Desmonts and J. Couvreur, Histoire naturelle de la toxoplasmose congénitale, Ann Pediatr, vol.31, pp.799-802, 1984.

J. P. Dubey and J. K. Frenkel, Cyst-Induced Toxoplasmosis in Cats*, The Journal of Protozoology, vol.1, issue.1, pp.155-177, 1972.
DOI : 10.1007/BF00348666

J. P. Dubey, A. W. Kotula, A. Sharar, C. D. Andrews, and D. S. Lindsay, Effect of High Temperature on Infectivity of Toxoplasma gondii Tissue Cysts in Pork, The Journal of Parasitology, vol.76, issue.2, pp.201-204, 1990.
DOI : 10.2307/3283016

J. P. Dubey, Infectivity and Pathogenicity of Toxoplasma gondii Oocysts for Cats, The Journal of Parasitology, vol.82, issue.6, pp.957-960, 1996.
DOI : 10.2307/3284206

J. P. Dubey, Bradyzoite-Induced Murine Toxoplasmosis: Stage Conversion, Pathogenesis, and Tissue Cyst Formation in Mice Fed Bradvzoites of - Different Strains of Toxoplasma gondii, Journal of Eukaryotic Microbiology, vol.42, issue.6
DOI : 10.1093/infdis/172.6.1561

J. P. Dubey, D. S. Lindsay, and C. A. Speer, Structures of Toxoplasma gondii tachyzoïtes, bradyzoïtes, and sporozoïtes and biology and development of tissue cysts, Clin Microbiol Reviews, vol.11, issue.2, pp.267-299, 1998.

J. P. Dubey, Toxoplasma gondii Oocyst Survival under Defined Temperatures, The Journal of Parasitology, vol.84, issue.4, pp.862-865, 1998.
DOI : 10.2307/3284606

K. T. Duffy, P. J. Wharton, J. D. Johnson, L. New, and R. E. Holliman, Assessment of immunoglobulin-M immunosorbent agglutination assay (ISAGA) for detecting toxoplasma specific IgM., Journal of Clinical Pathology, vol.42, issue.12, pp.1291-1296, 1989.
DOI : 10.1136/jcp.42.12.1291

H. Pelloux, New Vidas assay for Toxoplasma-specific IgG avidity : evaluation on 603 cases

C. Schaefer and J. Dupouy-camet, Congenital toxoplasmosis due to maternal reinfection during pregnancy, J Clin Microbiol, vol.35, issue.5, pp.1276-1283, 1997.

L. F. Giordano and E. P. Lasmar, Toxoplasmosis transmitted via kidney allograft: case report and review, Transplantation Proceedings, vol.34, issue.2, pp.498-507, 2002.
DOI : 10.1016/S0041-1345(02)02607-6

. Sérodiagnostic-de-la-toxoplasmose, Abbott) avec la trousse Vidas ® (bioMérieux), l'immunofluorescence indirecte et l'Isaga, Ann Biol Clin, vol.57, pp.481-485, 1999.

C. M. Grover, P. Thulliez, J. S. Remington, and J. C. Boothroyd, Rapid prenatal diagnosis of congenital Toxoplasma infection by using polymerase chain reaction and amniotic fluid, J

J. A. Hitt and G. A. Filice, Detection of Toxoplasma gondii parasitemia by gene amplification, cell culture, and mouse inoculation, J Clin Microbiol, vol.30, issue.12, pp.3181-3184, 1992.

P. Hohlfeld and J. Macaleese, Fetal toxoplasmosis: ultrasonographic signs, Ultrasound in Obstetrics and Gynecology, vol.1, issue.4, pp.241-245, 1991.
DOI : 10.1046/j.1469-0705.1991.01040241.x

G. N. Holland, R. E. Engstrom, and B. J. Glasgow, Ocular Toxoplasmosis in Patients with the Acquired Immunodeficiency Syndrome, American Journal of Ophthalmology, vol.106, issue.6, pp.653-67, 1988.
DOI : 10.1016/0002-9394(88)90697-6

R. Holliman, Maternal infections Part 1: Toxoplasmosis. Mod Midwife, pp.22-28, 1995.

D. Howe and L. D. Sibley, Toxoplasma gondii Comprises Three Clonal Lineages: Correlation of Parasite Genotype with Human Disease, Journal of Infectious Diseases, vol.172, issue.6, pp.1561-1567, 1995.
DOI : 10.1093/infdis/172.6.1561

C. Leport, J. Franck, G. Chêne, F. Derouin, J. L. Ecobichon et al., Immunoblot Profile as Predictor of Toxoplasmic Encephalitis in Patients Infected with Human Immunodeficiency Virus, Clinical and Vaccine Immunology, vol.8, issue.3, pp.579-84, 2001.
DOI : 10.1128/CDLI.8.3.579-584.2001

N. V. Levine, The protozoan phylum Apicomplexa, 1988.

P. Marty, Prenatal diagnosis of severe fetal toxoplasmosis as a result of toxoplasmic reactivation in an HIV-1 seropositive woman, Prenatal Diagnosis, vol.20, issue.5, pp.414-415, 1994.
DOI : 10.1002/pd.1970140514

A. Mele, P. J. Paterson, H. G. Prentice, P. Leoni, and C. C. Kibbler, Toxoplasmosis in bone marrow transplantation: a report of two cases and systematic review of the literature, Bone Marrow Transplantation, vol.14, issue.8, pp.691-699, 2002.
DOI : 10.1136/jcp.49.1.89

N. S. Morrissette, J. M. Murray, and D. S. Roos, Subpellicular microtubules associate with an intramembranous particle lattice in the protozoan parasite Toxoplasma gondii, J Cell Sci, vol.110, pp.35-42, 1997.

Y. Naot and J. S. Remington, An Enzyme-Linked Immunosorbent Assay for Detection of IgM Antibodies to Toxoplasma gondii: Use for Diagnosis of Acute Acquired Toxoplasmosis, Journal of Infectious Diseases, vol.142, issue.5, pp.757-66, 1980.
DOI : 10.1093/infdis/142.5.757

Y. Naot, G. Desmonts, and J. S. Remington, IgM enzyme-linked immunosorbent assay test for the diagnosis of congenital Toxoplasma infection, The Journal of Pediatrics, vol.98, issue.1, pp.32-36, 1981.
DOI : 10.1016/S0022-3476(81)80528-8

J. A. Nicolas, Pestre-Alexandre M. Toxoplasmose : une zoonose transmissible à l'homme

C. Nicolle and L. Manceaux, Sur un protozoaire nouveau du gondii : toxoplasme, Arch Inst Pasteur Tunis, vol.2, pp.97-103, 1909.

B. A. Nichols, M. L. Chiappino, and G. R. O-'connor, Secretion from the Rhoptries of Toxoplasma gondii during host-cell invasion, Journal of Ultrastructure Research, vol.83, issue.1, pp.85-98, 1983.
DOI : 10.1016/S0022-5320(83)90067-9

F. Foudrinier and H. Lepan, Detection of specific immunoglobulin E in patients with toxoplasmosis, J Clin Microbiol, vol.28, issue.8, pp.1739-1782, 1990.

J. M. Pinon and C. Chemla, Early neonatal diagnosis of congenital toxoplasmosis value of comparative enzyme linked immunofiltration assay immunological profiles and anti toxoplasma gondii immunoglobulin m or Iga immunocapture and implications for postnatal the therapeutic strategies, J Clin Microbial, vol.34, pp.579-83, 1996.

C. Pomeroy, G. A. Filice, J. A. Hitt, and M. C. Jordan, Cytomegalovirus-Induced Reactivation of Toxoplasma gondii Pneumonia in Mice: Lung Lymphocyte Phenotypes and Suppressor Function, Journal of Infectious Diseases, vol.166, issue.3
DOI : 10.1093/infdis/166.3.677

F. Raffi and M. Tiab, Cerebral toxoplasmosis concomitant with primary toxoplasma infection in AIDS, Presse Med, vol.21, issue.12, pp.584-589, 1992.

R. J. Cavanaugh and E. N. , Isolation of the encysted form of toxoplasma gondii from human skeletal muscle and brain, N Engl J Med, vol.273, issue.24, pp.1308-1318, 1965.

R. J. Thulliez and P. , Recent developments for diagnosis of toxoplasmosis, J Clin Microbiol, vol.42, issue.3, pp.941-946, 2004.

F. Robert-gangneux, M. F. Gavinet, T. Ancelle, J. Raymond, C. Tourte-schaefer et al., Value of prenatal diagnosis and early postnatal diagnosis of congenital toxoplasmosis retrospective study of 110 cases, J Clin Microbiol, vol.37, issue.9, pp.2893-2901, 1999.

F. Roberts and R. Mc-leod, Pathogenesis of Toxoplasmic Retinochoroiditis, Parasitology Today, vol.15, issue.2, pp.51-58, 1999.
DOI : 10.1016/S0169-4758(98)01377-5

S. J. Romand, R. Nobre, and P. Thulliez, Toxoplasmose et grossesse, Médecine thérapeutique/Pédiatrie, vol.1, issue.6, pp.481-489, 1998.

S. Romand, M. Wallon, J. Franck, P. Thulliez, F. Peyron et al., Prenatal diagnosis using polymerase chain reaction on amniotic fluid for congenital toxoplasmosis, Obstet Gynecol, vol.97, issue.2, pp.296-300, 2001.
DOI : 10.1016/s0029-7844(00)01118-2

E. Rorman and C. S. Zamir, Congenital toxoplasmosis???prenatal aspects of Toxoplasma gondii infection, Reproductive Toxicology, vol.21, issue.4, pp.458-72, 2006.
DOI : 10.1016/j.reprotox.2005.10.006

A. B. Sabin, Toxoplasmosis a recently recognized disease of human beings, Adv Pediat, vol.1, issue.1, 1942.

A. B. Sabin and H. A. Feldman, Dyes as microchemical indicators of a new Science, pp.660-663, 1948.

H. G. Sheffield and M. L. Melton, The Fine Structure and Reproduction of Toxoplasma gondii, The Journal of Parasitology, vol.54, issue.2, pp.209-226, 1968.
DOI : 10.2307/3276925

M. Schweitzer and O. Thiebaugeorges, La prévention de la toxoplasmose congénitale en

. France, Evaluation des risques Résultats et perspectives du dépistage anténatal et du suivi du nouveau-né, Bull Acad Natl Med, vol.185, pp.665-88, 2001.

D. Soldati, The Apicoplast as a Potential Therapeutic Target in Toxoplasma and Other Apicomplexan Parasites, Parasitology Today, vol.15, issue.1, pp.5-7, 1999.
DOI : 10.1016/S0169-4758(98)01363-5