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A. Lysis and /. Bufferis, ADN, dénaturation des protéines 4) Ajouts des particules magnétiques (MGPs Magntic Glass Particles), les conditions induites par les agents chaotropiques, l'isopropanol et le pouvoir ionisant du Lysis/Binding Bufferis sont telles que l'ADN se fixe sur la silice présente à la surface de ces particules. 5) Séparation magnétique des MGPs avec l'ADN lié du reste du lysat 6) Purification de l'ADN lié et élimination des nucléases, membranes cellulaires