Chimie physique générale, Chimie thérapeutique Bertrand RIHN ................................................. Biochimie ,
Chimie thérapeutique Chimie thérapeutique ,
Biophysique-acoustique 6 ,
Biophysique, Chimie organique Caroline PERRIN-SARRADO ........................ Pharmacologie Virginie PICHON ,
Pharmacie galénique PROFESSEUR ASSOCIE, Biochimie et Biologie ,
Anglais ,
CsA+Méthylprednisolone n=37 (9,5%) La CsA a été utilisée seule dans 24 cas (6,1%) et le MTX seul dans dix cas (2,6%); deux patients (0,5%) n'ont pas eu de prophylaxie. Les patients ayant bénéficié de SAL n=229, p.5 ,
Genomic polymorphism, growth properties, and immunologic variations in human herpesvirus-6 isolates, Virology, vol.184, issue.2, pp.545-52, 1991. ,
DOI : 10.1016/0042-6822(91)90424-A
HBLV (orHHV-6) in human cell lines, Nature, vol.329, issue.6136, p.207, 1987. ,
DOI : 10.1038/329207a0
INFECTION CONCOMITANT WITH PEDIATRIC RENAL ALLOGRAFT REJECTION, Transplantation, vol.62, issue.5, pp.689-91, 1996. ,
DOI : 10.1097/00007890-199609150-00026
Congenital Infections with Human Herpesvirus 6, Journal of Infectious Diseases, vol.178, issue.2, pp.544-550, 1998. ,
DOI : 10.1086/517470
URL : https://academic.oup.com/jid/article-pdf/178/2/544/2684994/178-2-544.pdf
Homogeneous Susceptibility of Distinct Human Herpesvirus 6 Strains to Antivirals In Vitro, Journal of Infectious Diseases, vol.163, issue.6, pp.1382-1385, 1991. ,
DOI : 10.1093/infdis/163.6.1382
Severe Infectious Mononucleosis-like Syndrome and Primary Human Herpesvirus 6 Infection in an Adult, New England Journal of Medicine, vol.329, issue.3, pp.168-71, 1993. ,
DOI : 10.1056/NEJM199307153290304
Reactivation of human herpesvirus 6 during ex vivo expansion of circulating CD34+ haematopoietic stem cells, Journal of General Virology, vol.85, issue.11, pp.3333-3339, 2004. ,
DOI : 10.1099/vir.0.80319-0
The U69 gene of human herpesvirus 6 encodes a protein kinase which can confer ganciclovir sensitivity to baculoviruses, J Virol, vol.73, pp.3284-91, 1999. ,
Clinical features of infants with primary human herpesvirus 6 infection (exanthem subitum, roseola infantum), Pediatrics, vol.93, pp.104-112, 1994. ,
Intrauterine transmission of human herpesvirus 6 Identification of proteins specific for human herpesvirus 6-infected human T cells, Lancet J Virol, vol.34063, issue.14, pp.482-32835, 1989. ,
Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system, Antiviral Research, vol.54, issue.1, pp.59-67, 2002. ,
DOI : 10.1016/S0166-3542(01)00211-X
Human herpesvirus-6 infection in children with first febrile seizures, The Journal of Pediatrics, vol.127, issue.1, pp.95-102, 1995. ,
DOI : 10.1016/S0022-3476(95)70263-6
Fatal human herpesvirus 6-associated multifocal meningoencephalitis in an adult female patient ,
Successful treatment of human herpesvirus-6 encephalitis after bone marrow transplantation, Bone Marrow Transplantation, vol.24, issue.11, pp.1245-1253, 1999. ,
DOI : 10.1038/sj.bmt.1702065
Seroprevalence of anti-human herpes virus-6 IgG antibody in children of Bangkok, Thailand. Southeast Asian J Trop Med Public Health, vol.32, pp.143-150, 2001. ,
Ultrastructural characterization of a new human B lymphotropic DNA virus (human herpesvirus 6) isolated from patients with lymphoproliferative disease, J Natl Cancer Inst, vol.79, pp.933-974, 1987. ,
Severe meningoencephalitis caused by human herpesvirus 6 type B in an immunocompetent woman treated with ganciclovir Induction of host cell protein synthesis by human herpesvirus 6, Clin Infect Dis Virus Res Black JB Rev Med Virol, vol.40229, issue.23, pp.887-913, 1992. ,
Human Herpesvirus 6 Genome Integration: A Possible Cause of Misdiagnosis of Active Viral Infection?, The Journal of Infectious Diseases, vol.94, issue.7, pp.1019-1039, 2006. ,
DOI : 10.1097/00007890-200006270-00002
Human herpesvirus 6, Clin Microbiol Rev, vol.10, pp.521-67, 1997. ,
Role of protein-protein interactions in the function of replication protein A (RPA): RPA modulates the activity of DNA polymerase alpha by multiple mechanisms Age prevalence of antibody to human herpesvirus 6, Biochemistry Lancet, vol.361, issue.28, pp.8443-541058, 1988. ,
Automated morphometric analysis in peripheral neuropathies Human herpesvirus 6 (HHV-6) isolation from bone marrow: HHV-6-associated bone marrow suppression in bone marrow transplant patients, Comput Biol Med Blood, vol.2984, issue.30, pp.147-563307, 1994. ,
Human herpesvirus 6, Reviews in Medical Virology, vol.20, issue.3, pp.155-73, 2000. ,
DOI : 10.1038/sj.bmt.1700988
Quantification of Human Herpesvirus 6 in Immunocompetent Persons and Post-mortem Tissues from AIDS Patients by PCR, Journal of General Virology, vol.77, issue.9, pp.2271-2276, 1996. ,
DOI : 10.1099/0022-1317-77-9-2271
Transmission of Integrated Human Herpesvirus 6 through Stem Cell Transplantation: Implications for Laboratory Diagnosis, The Journal of Infectious Diseases, vol.193, issue.7, pp.912-918, 2006. ,
DOI : 10.1086/500838
Importance of chromosomally integrated HHV-6A and -6B in the diagnosis of active HHV-6 infection Real-time PCR for quantification of human herpesvirus 6 DNA from lymph nodes and saliva, Herpes J Clin Microbiol, vol.1540, issue.38, pp.28-322445, 2002. ,
Human herpesvirus 6 in lung tissue from patients with pneumonitis after bone marrow transplantation Inheritance of chromosomally integrated human herpesvirus 6 DNA Chromosomal transmission of human herpesvirus 6 DNA in acute lymphoblastic leukaemia, N Engl J Med Blood Lancet, vol.32994352, issue.40, pp.156-611545, 1993. ,
Update on Human Herpesvirus 6 Biology, Clinical Features, and Therapy, Clinical Microbiology Reviews, vol.18, issue.1, pp.217-262, 2005. ,
DOI : 10.1128/CMR.18.1.217-245.2005
Quantitative analysis of human herpesvirus 6 cell tropism Human herpesvirus type 6 reactivation after haematopoietic stem cell transplantation, J Med Virol J Clin Virol, vol.7543, issue.44, pp.76-85361, 2005. ,
in children: an important risk factor for clinical outcome Detection of human herpesviruses HHV-6, HHV-7 and HHV-8 in whole blood by real-time PCR using the new CMV, HHV-6, 7, 8 R-gene kit Successful treatment of human herpesvirus 6 encephalomyelitis in immunocompetent patient, Human herpes virus 6 plasma DNA positivity after hematopoietic stem cell transplantation, pp.831-840, 2004. ,
Foscarnet Nephrotoxicity: Mechanism, Incidence and Prevention, American Journal of Nephrology, vol.9, issue.4, pp.316-337, 1989. ,
DOI : 10.1159/000167987
Human Herpesvirus 6 Reactivation Is Associated with Cytomegalovirus Infection and Syndromes in Kidney Transplant Recipients at Risk for Primary Cytomegalovirus Infection, The Journal of Infectious Diseases, vol.178, issue.6, pp.1783-1789, 1998. ,
DOI : 10.1086/314510
The replication of viral and cellular DNA in human herpesvirus 6-infected cells, Virology, vol.175, issue.1, pp.199-210, 1990. ,
DOI : 10.1016/0042-6822(90)90200-B
Human herpesviruses 6 and 7 in salivary glands and shedding in saliva of healthy and human immunodeficiency virus positive individuals, Journal of Medical Virology, vol.66, issue.4, pp.462-470, 1995. ,
DOI : 10.1093/infdis/168.1.250
Human herpesvirus 6: molecular biology and clinical features, Journal of Medical Microbiology, vol.52, issue.1, pp.5-18, 2003. ,
DOI : 10.1099/jmm.0.05074-0
URL : http://jmm.microbiologyresearch.org/deliver/fulltext/jmm/52/1/JMM5201.5.pdf?itemId=/content/journal/jmm/10.1099/jmm.0.05074-0&mimeType=pdf&isFastTrackArticle=
Human herpesvirus-6 and -7 in transplantation, Reviews in Medical Virology, vol.67, issue.1, pp.23-36, 2001. ,
DOI : 10.1097/00007890-199902150-00010
Seroconversion to Human Herpesvirus 6 following Liver Transplantation Is a Marker of Cytomegalovirus Disease, The Journal of Infectious Diseases, vol.176, issue.5, pp.1135-1175, 1997. ,
DOI : 10.1086/514104
Human herpesvirus 6B genome sequence: coding content and comparison with human herpesvirus 6A ,
Brief report: fatal encephalitis due to variant B human herpesvirus-6 infection in a bone marrow-transplant recipient Emery VC. Human herpesviruses 6 and 7 in solid organ transplant recipients, N Engl J Med Clin Infect Dis, vol.33032, issue.58, pp.1356-601357, 1994. ,
Adenovirus infection after allogeneic stem cell transplantation Human herpesvirus 6 induces interleukin-1 beta and tumor necrosis factor alpha, but not interleukin-6, in peripheral blood mononuclear cell cultures Immunosuppressive effect of human herpesvirus 6 on T-cell functions: suppression of interleukin-2 synthesis and cell proliferation Human herpesvirus-6 enhances natural killer cell cytotoxicity via IL-15 Selection of a monoclonal antibody specific for variant B human herpesvirus 6-infected mononuclear cells Monoclonal antibodies to gp100 inhibit penetration of human herpesvirus 6 and polykaryocyte formation in susceptible cells Human herpesvirus 6 in salivary glands al. Different expression of human herpesvirus-6 (HHV-6) load in whole blood may have a significant impact on the diagnosis of active infection Development of a real-time polymerase chain reaction assay for the diagnosis of human herpesvirus-6 infection and application to bone marrow transplant patients, Prevalence of antibodies to human herpesvirus 6 in different age groups, pp.12-5244, 1990. ,
CLINICAL MANIFESTATIONS OF GRAFT-VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL-A-MATCHED SIBLING DONOR,S, Transplantation, vol.18, issue.4, pp.295-304, 1974. ,
DOI : 10.1097/00007890-197410000-00001
Active human herpesvirus 6 infection in an adolescent male Characterization of human telomeric repeat sequences from human herpesvirus 6 and relationship to replication The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution, Clin Infect Dis J Gen Virol Virology, vol.2076209, pp.1070-1071, 1995. ,
HERPES-VIRUS IMMUNITY AND ACUTE GRAFT-VERSUS-HOST DISEASE, The Lancet, vol.329, issue.8531, pp.2680-2682, 1987. ,
DOI : 10.1016/S0140-6736(87)92088-5
Pathogenic Effects of Human Herpesvirus 6 in Human Lymphoid Tissue Ex Vivo, Journal of Virology, vol.77, issue.15, pp.8280-8289, 2003. ,
DOI : 10.1128/JVI.77.15.8280-8289.2003
Chromosomal integration of human herpesvirus 6 is the major mode of congenital human herpesvirus 6 infection Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant A, Pediatrics Clin Infect Dis, vol.12226, issue.76, pp.513-20132, 1998. ,
Human herpesvirus-6 infection in children. A prospective study of complications and reactivation Impact of human herpesvirus-6 after haematopoietic stem cell transplantation, N Engl J Med Br J Haematol, vol.331128, issue.78, pp.432-866, 1994. ,
Inheritance of chromosomally integrated viral DNA?, Blood, vol.95, pp.1108-1117, 2000. ,
Failure of multiple antivirals to affect high HHV-6 DNAaemia resulting from viral chromosomal integration in case of severe aplastic anaemia Herpesvirus prevalence and viral load in healthy blood donors by quantitative real-time polymerase chain reaction Clinical impact of human herpesvirus 6 infection after liver transplantation, Disappearance of pre-existing high HHV-6 DNA load in blood after allogeneic SCT, pp.805-811, 2002. ,
Human herpesvirus 6 infection after autologous or allogeneic stem cell transplantation: a single-center prospective longitudinal study of 92 patients Comparison of the complete DNA sequences of human herpesvirus 6 variants A and B, Clin Infect Dis J Virol, vol.3173, issue.86, pp.881-68053, 1999. ,
Severe allograft dysfunction after OKT3-induced human herpes virus-6 reactivation, Transplant Proc, vol.26, pp.3121-88, 1994. ,
Chromosomally Integrated HHV-6: Slow Decrease of HHV-6 Viral Load After Hematopoietic Stem-Cell Transplantation, Transplantation, vol.88, issue.9, pp.1142-1145, 2009. ,
DOI : 10.1097/TP.0b013e3181bb98e4
Contribution of human herpesvirus 6 (HHV-6) viral load in whole blood and serum to investigate integrated HHV-6 transmission after haematopoietic stem cell transplantation, Journal of Clinical Virology, vol.45, issue.1, pp.43-49, 2009. ,
DOI : 10.1016/j.jcv.2009.02.006
Genomic analysis of the human B-lymphotropic virus (HBLV), Science, vol.234, pp.601-604, 1986. ,
Human herpesvirus 6 (HHV-6) ORF-1 transactivating gene exhibits malignant transforming activity and its protein binds to p53, Oncogene, vol.14, issue.3, pp.359-67, 1997. ,
DOI : 10.1038/sj.onc.1200840
URL : http://www.nature.com/onc/journal/v14/n3/pdf/1200840a.pdf
Acute cerebellitis in primary human herpesvirus-6 infection Chronic myelosuppression associated with persistent bone marrow infection due to human herpesvirus 6 in a bone marrow transplant recipient, Eur J Pediatr Clin Infect Dis, vol.16222, pp.801-3174, 1996. ,
Fulminant human herpesvirus six encephalitis in a human immunodeficiency virus-infected infant Latent human herpesvirus 6 infection of human monocytes/macrophages Association of human herpesvirus 6 infection of the central nervous system with recurrence of febrile convulsions, J Med Virol J Gen Virol J Infect Dis, vol.4572167, issue.97, pp.288-921197, 1991. ,
Identification of human herpesvirus 6 latency-associated transcripts Clinical indications and diagnostic techniques of human herpesvirus-6 (HHV-6) infection, J Virol In Vivo Lancet, vol.765336, issue.101, pp.4145-51287, 1990. ,
An Immunoblot Assay for Detection of Immunoglobulin M Antibody to Human Herpesvirus 6, Clinical and Vaccine Immunology, vol.7, issue.5, pp.823-830, 2000. ,
DOI : 10.1128/CDLI.7.5.823-827.2000
Primary human herpes virus 6 infection transmitted from donor to recipient through bone marrow infusion, Bone Marrow Transplantation, vol.21, issue.10, pp.1063-1069, 1998. ,
DOI : 10.1038/sj.bmt.1701230
URL : http://www.nature.com/bmt/journal/v21/n10/pdf/1701230a.pdf
TaqMan PCR-based gene dosage assay for predictive testing in individuals from a cancer family with INK4 locus haploinsufficiency Human herpesvirus-6 infection after liver transplantation Human herpesvirus-6 antigenemia after liver transplantation, Clin Chem Clin Infect Dis Transplantation, vol.452669, issue.106, pp.982-6702, 1998. ,
The prevalence of chromosomally integrated human herpesvirus 6 genomes in the blood of UK blood donors Frequent isolation of HHV-6 from saliva and high seroprevalence of the virus in the population, J Med Virol Lancet, vol.79335, issue.108, pp.45-511047, 1990. ,
Interferon-gamma (IFN-gamma) regulates production of IL-10 and IL-12 in human herpesvirus-6 (HHV-6)-infected monocyte/macrophage lineage, Clinical and Experimental Immunology, vol.109, issue.3 ,
DOI : 10.1046/j.1365-2249.1997.4661362.x
High levels of human herpesvirus 6 DNA in peripheral blood leucocytes are correlated to platelet engraftment and disease in allogeneic stem cell transplant patients, Clin Exp Immunol Br J Haematol, vol.109111, issue.110, pp.421-5774, 1997. ,
Human Herpesvirus 6 Latency Characterized by High Viral Load: Chromosomal Integration in Many, but Not All, Cells, The Journal of Infectious Diseases, vol.95, issue.7, pp.1020-1021, 2006. ,
DOI : 10.1002/(SICI)1096-9071(199905)58:1<69::AID-JMV11>3.0.CO;2-3
Human herpesvirus 6 latently infects early bone marrow progenitors in vivo, J Virol, vol.73, pp.754-763, 1999. ,
Three cases of human herpesvirus-6 latent infection: Integration of viral genome in peripheral blood mononuclear cell DNA, Journal of Medical Virology, vol.69, issue.1, pp.44-52, 1993. ,
DOI : 10.1093/infdis/157.6.1271
HHV-6 and the immune system: mechanisms of immunomodulation and viral escape, Journal of Clinical Virology, vol.37, issue.1, pp.4-10, 2006. ,
DOI : 10.1016/S1386-6532(06)70004-X
9 Human herpesvirus 6, Bailli??re's Clinical Haematology, vol.8, issue.1, pp.201-224, 1995. ,
DOI : 10.1016/S0950-3536(05)80238-0
Infection of gamma/delta T lymphocytes by human herpesvirus 6: transcriptional induction of CD4 and susceptibility to HIV infection Productive infection of CD4+ and CD8+ mature human T cell populations and clones by human herpesvirus 6. Transcriptional down-regulation of CD3, vitro cellular tropism of human B-lymphotropic virus, pp.1303-10685, 1988. ,
Diverse tropism of HBLV (human herpesvirus 6), Lancet, vol.2, issue.120, p.743, 1987. ,
Real-Time PCR as a Versatile Tool for Investigating the Susceptibility of Human Herpesvirus 6 to Antiviral Agents, Antimicrobial Agents and Chemotherapy, vol.47, issue.9, pp.3021-3025, 2003. ,
DOI : 10.1128/AAC.47.9.3021-3024.2003
Chronic myelopathy associated with human herpesvirus-6 Outcomes of infants whose mothers are positive for human herpesvirus-6 DNA within the genital tract in early gestation, Neurology Acta Paediatr Jpn Cytometry, vol.453940, issue.123, pp.2015-7653, 1995. ,
Selection of the same mutation in the U69 protein kinase gene of human herpesvirus-6 after prolonged exposure to ganciclovir in vitro and in vivo, Journal of General Virology, vol.1, issue.11, pp.2767-761153, 2001. ,
DOI : 10.1034/j.1600-0404.2000.09001.x
Human beta-herpesvirus interactions in solid organ transplant recipients Temporal mapping of transcripts in herpesvirus 6 variants, J Infect Dis J Virol, vol.18372, issue.127, pp.179-1843837, 1998. ,
Encephalitis Caused by Human Herpesvirus-6 in a Liver Transplant Recipient, European Neurology, vol.48, issue.4, pp.234-239, 2002. ,
DOI : 10.1159/000066172
Human herpes virus-6 encephalitis after bone marrow transplantation: successful treatment with ganciclovir, Bone Marrow Transplantation, vol.20, issue.10, pp.905-911, 1997. ,
DOI : 10.1038/sj.bmt.1700988
URL : http://www.nature.com/bmt/journal/v20/n10/pdf/1700988a.pdf
Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae, J Virol, vol.70, pp.549-58, 1996. ,
Recent topics related to human herpesvirus 6 cell tropism, Cellular Microbiology, vol.352, issue.7, pp.1001-1007, 2009. ,
DOI : 10.1111/j.1462-5822.2009.01312.x
URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1462-5822.2009.01312.x/pdf
The Human Herpesvirus 6 U100 Gene Product Is the Third Component of the gH-gL Glycoprotein Complex on the Viral Envelope, Journal of Virology, vol.77, issue.4 ,
DOI : 10.1128/JVI.77.4.2452-2458.2003
Discovery of a Second Form of Tripartite Complex Containing gH-gL of Human Herpesvirus 6 and Observations on CD46, Journal of Virology, vol.78, issue.9, pp.4609-4625, 2004. ,
DOI : 10.1128/JVI.78.9.4609-4616.2004
Human Herpesvirus 6 Variant A but Not Variant B Induces Fusion from Without in a Variety of Human Cells through a Human Herpesvirus 6 Entry Receptor, CD46, Journal of Virology, vol.76, issue.13, pp.6750-61, 2002. ,
DOI : 10.1128/JVI.76.13.6750-6761.2002
Human Herpesvirus 6 Variant A Glycoprotein H-Glycoprotein L-Glycoprotein Q Complex Associates with Human CD46, Journal of Virology, vol.77, issue.8, pp.4992-5001, 2003. ,
DOI : 10.1128/JVI.77.8.4992-4999.2003
Fine mapping of an apparently targeted latent human herpesvirus type 6 integration site in chromosome band 17p13.3 Human herpesvirus 6 infection in renal-transplant recipients, J Med Virol N Engl J Med, vol.58320, issue.137, pp.69-751560, 1989. ,
Molecular epidemiological studies of human herpesvirus 6 in families Human herpesvirus 6 integrates within telomeric regions as evidenced by five different chromosomal sites Detection of IgM antibodies to human herpesvirus 6 in Romanian children with nonprogressive human immunodeficiency virus disease, J Med Virol J Med Virol Pediatr Infect Dis J, vol.428014, issue.140, pp.224-71952, 1994. ,
Replication of human herpesvirus 6 (HHV-6): morphological aspects Human herpesvirus 6 DNA in plasma after allogeneic stem cell transplantation: incidence and clinical significance, Adv Exp Med Biol J Infect Dis, vol.278193, issue.142, pp.19-2868, 1990. ,
Human herpesviruses 6 and 7 in cervixes of pregnant women Analysis of human herpesvirus 6 glycoproteins recognized by monoclonal antibody OHV1, Human herpesvirus 6 infection in renal transplantation, pp.519-221968, 1990. ,
An enzyme-linked immunosorbent assay for the detection of IgG and IgM antibodies to human herpesvirus type 6, Journal of Virological Methods, vol.41, issue.3, pp.265-75, 1993. ,
DOI : 10.1016/0166-0934(93)90017-L
Encephalopathy associated with human herpesvirus 6 in a liver transplant recipient Induction of cell-cell fusion from without by human herpesvirus 6B, Liver Transpl Surg J Virol, vol.580, issue.150, pp.454-59916, 1999. ,
HIV-1 and HHV-6 antigens and transcripts in retinas of patients with AIDS in the absence of human cytomegalovirus Infections with human herpesvirus 6 variant B delay platelet engraftment after allogeneic haematopoietic stem cell transplantation Seroepidemiology of human herpesvirus-6 in pregnant women from different parts of the world, Invest Ophthalmol Vis Sci Br J Haematol J Med Virol, vol.3613134, issue.152, pp.2040-7480, 1991. ,
Antiviral prophylaxis may prevent human herpesvirus-6 reactivation in bone marrow transplant recipients, Transplant Infectious Disease, vol.28, issue.1, pp.10-16, 2002. ,
DOI : 10.1046/j.1365-2141.1999.01443.x
U94, the Human Herpesvirus 6 Homolog of the Parvovirus Nonstructural Gene, Is Highly Conserved among Isolates and Is Expressed at Low mRNA Levels as a Spliced Transcript, Virology, vol.268, issue.2, pp.504-520, 2000. ,
DOI : 10.1006/viro.1999.0163
In Situ Detection of Human Herpesvirus 6 in Retinitis Associated with Acquired Immunodeficiency Syndrome, American Journal of Ophthalmology, vol.114, issue.3, pp.375-382, 1992. ,
DOI : 10.1016/S0002-9394(14)71814-8
Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6, Antiviral Research, vol.28, issue.4, pp.343-57, 1995. ,
DOI : 10.1016/0166-3542(95)00058-5
Difference in permissiveness of human fibroblast cells to variants A and B of human herpesvirus-6, Research in Virology, vol.147, issue.4, pp.219-244, 1996. ,
DOI : 10.1016/0923-2516(96)89652-X
HUMAN HERPESVIRUS-6 IN LIVER TRANSPLANT RECIPIENTS, Transplantation, vol.69, issue.12, pp.2566-73, 2000. ,
DOI : 10.1097/00007890-200006270-00016
Fatal primary infection due to human herpesvirus 6 variant A in a renal transplant recipient U94 of human herpesvirus 6 is expressed in latently infected peripheral blood mononuclear cells and blocks viral gene expression in transformed lymphocytes in culture, Transplantation Proc Natl Acad Sci U S A, vol.7195, issue.162, pp.288-9213911, 1998. ,
Mapping ganciclovir resistance in the human herpesvirus-6 U69 protein kinase, Journal of Medical Virology, vol.36, issue.3, pp.434-443, 2003. ,
DOI : 10.1016/S0166-3542(97)00034-X
Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders, Science, vol.234, issue.4776, pp.596-601, 1986. ,
DOI : 10.1126/science.2876520
CD46 Is a Cellular Receptor for Human Herpesvirus 6, Cell, vol.99, issue.7, pp.817-844, 1999. ,
DOI : 10.1016/S0092-8674(00)81678-5
High incidence of human herpesvirus 6 infection with a high viral load in cord blood stem cell transplant recipients, Blood, vol.100, pp.2005-2016, 2002. ,
Human herpesvirus-6 and -7 in pediatric stem cell transplantation, Pediatric Blood & Cancer, vol.335, issue.6, pp.820-825, 2005. ,
DOI : 10.1093/infdis/167.3.735
Human herpesvirus-6 in transplantation: an emerging pathogen Human herpesvirus-6 infection in liver transplant recipients: documentation of pathogenicity Variant B human herpesvirus-6 associated febrile dermatosis with thrombocytopenia and encephalopathy in a liver transplant recipient Encephalitis caused by human herpesvirus-6 in transplant recipients: relevance of a novel neurotropic virus, J Infect Dis Ann Intern Med Transplantation Transplantation Transplantation, vol.166124646069, issue.171, pp.202-207, 1992. ,
Fulminant hepatitis in primary human herpesvirus-6 infection Role of viruses in etiology and pathogenesis of multiple sclerosis, N Engl J Med Adv Virus Res, vol.32456, issue.174, pp.1290517-55, 1991. ,
Clinical features of primary HHV-6 and HHV-7 infections] IgM neutralizing antibody responses to human herpesvirus-6 in patients with exanthem subitum or organ transplantation, Nippon Rinsho Microbiol Immunol, vol.5636, issue.176, pp.203-7495, 1992. ,
A case of human herpesvirus-6 lymphadenitis with infectious mononucleosis-like syndrome, Pathology International, vol.329, issue.12, pp.947-51, 1995. ,
DOI : 10.1111/j.1348-0421.1989.tb02001.x
human herpesvirus 6-related virus Identification of a variant A-specific neutralizing epitope on glycoprotein B (gB) of human herpesvirus-6 (HHV-6), J Virol Virology, vol.63222, issue.180, pp.3161-3176, 1989. ,
HHV-6) is transmitted from parent to child in an integrated form and characterization of cases with chromosomally integrated HHV-6 DNA Human herpesvirus-6 encephalitis after unrelated cord blood transplantation, J Med Virol Leuk Lymphoma, vol.67346, issue.181, pp.465-73561, 2004. ,
Structure of Transcripts and Proteins Encoded by U79-80 of Human Herpesvirus 6 and Its Subcellular Localization in Infected Cells, Virology, vol.271, issue.2, pp.307-327, 2000. ,
DOI : 10.1006/viro.2000.0326
Structure and heterogeneity of the a sequences of human herpesvirus 6 strain variants U1102 and Z29 and identification of human telomeric repeat sequences at the genomic termini, J Virol, vol.68, pp.3007-3021, 1994. ,
Fatal herpesvirus-6 encephalitis in a recipient of a T-cell-depleted peripheral blood stem cell transplant from a 3-loci mismatched related donor Ganciclovir is effective for prophylaxis and treatment of human herpesvirus-6 in allogeneic stem cell transplantation, Haematologica Bone Marrow Transplant, vol.8529, issue.185, pp.94-7595, 2000. ,
Targeted integration of human herpesvirus 6 in the p arm of chromosome 17 of human peripheral blood mononuclear cells in vivo, Journal of Medical Virology, vol.83, issue.3, pp.178-88, 1995. ,
DOI : 10.1093/ajcp/93.6.776
Pathogenic Mechanisms of Meningitis/Encephalitis Caused by Human Herpesvirus-6 in Immunocompetent Adult Patients, Clinical Infectious Diseases, vol.29, issue.1, pp.422-425, 2005. ,
DOI : 10.1016/0168-1702(93)90127-9
Prevalence of human herpesvirus-6 in allogeneic hematopoietic stem cell transplant recipients in correlation with cytomegalovirus infection ,
Correlations of human herpesvirus 6B and CMV infection with acute GVHD in recipients of allogeneic haematopoietic stem cell transplantation Primary human herpesvirus-6 infection is frequently overlooked as a cause of febrile fits in young children, Bone Marrow Transplant J Med Virol, vol.4242, pp.673-7119, 0194. ,
Seroprevalence of human herpesvirus-6 in healthy population in two provinces of north China Risk factors for developing human herpesvirus 6 (HHV-6) reactivation after allogeneic hematopoietic stem cell transplantation and its association with central nervous system disorders, Chin Med Sci J Biol Blood Marrow Transplant, vol.1213, pp.111-4100, 1997. ,
IDENTIFICATION OF HUMAN HERPESVIRUS-6 AS A CAUSAL AGENT FOR EXANTHEM SUBITUM, The Lancet, vol.331, issue.8594, pp.1065-1072, 1988. ,
DOI : 10.1016/S0140-6736(88)91893-4
Human herpesvirus 6 meningoencephalitis successfully treated with ganciclovir in a patient who underwent allogeneic bone marrow transplantation from an HLA-identical sibling Electron microscopic study of a herpes-type virus isolated from an infant with exanthem subitum, Int J Hematol Microbiol Immunol, vol.7533, issue.201, pp.421-5147, 1989. ,
Human herpesvirus 6 infection in hematopoietic stem cell transplant patients, British Journal of Haematology, vol.54, issue.4, pp.421-453, 2004. ,
DOI : 10.1086/338044
Central nervous system complications in human herpesvirus-6 infection, Brain and Development, vol.22, issue.5, pp.307-321, 2000. ,
DOI : 10.1016/S0387-7604(00)00113-3
Human Herpesvirus 6 Viremia in Bone Marrow Transplant Recipients: Clinical Features and Risk Factors, The Journal of Infectious Diseases, vol.185, issue.7, pp.847-53, 2002. ,
DOI : 10.1086/339411
FOUR CASES OF HUMAN HERPESVIRUS 6 VARIANT B INFECTION AFTER PEDIATRIC LIVER TRANSPLANTATION, Transplantation, vol.65, issue.9, pp.1266-1275, 1998. ,
DOI : 10.1097/00007890-199805150-00021
Human herpesvirus-6 infection in bone marrow transplantation Clinical outcomes of human herpesvirus 6 reactivation after hematopoietic stem cell transplantation Effect of antivirals on human herpesvirus 6 replication in hematopoietic stem cell transplant recipients, Blood Clin Infect Dis Clin Infect Dis, vol.784034, issue.208, pp.1381-4932, 1991. ,
ADN, dénaturation des protéines 4) Ajouts des particules magnétiques (MGPs Magntic Glass Particles), les conditions induites par les agents chaotropiques, l'isopropanol et le pouvoir ionisant du Lysis/Binding Bufferis sont telles que l'ADN se fixe sur la silice présente à la surface de ces particules. 5) Séparation magnétique des MGPs avec l'ADN lié du reste du lysat 6) Purification de l'ADN lié et élimination des nucléases, membranes cellulaires ,