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. Cette-Étude-rétrospective, monocentrique, évalue l'évolution de la survie, du nombre d'hospitalisations pour exacerbation et des paramètres fonctionnels des patients BPCO traités par VNI à domicile entre, 1990.

3. Kg, /. M2, and . Vems, PaO2 air ambiant: 62±9 mmHg, PaCO2 air ambiant: 51±8 mmHg, PaCO2 sous O2 : 57±10mmHg) La médiane de survie est de 36 mois, la survie du groupe 2 est meilleure dans la première période (avant 2001) de façon significative, les hospitalisations pour exacerbation de BPCO sont réduites de 42% (p=0.002) après 12 mois de VNI (-62% vs -17%, respectivement dans le groupe 1 et 2) Après 3 mois de VNI, il n'y a pas d'amélioration cliniquement significative de l'hématose ni de la CVF et du VEMS, En analyse multivariée, les facteurs de risque de mortalité étaient l'âge et les maladies cardiovasculaires (insuffisance cardiaque, AOMI) et une dyslipidémie, pp.34-49

T. En-anglais, evolution of survival, hospitalization and respiratory parameters in COPD patients treated with domiciliary NIV between 1990 and 2012 at Nancy Hospital THÈSE, p.2014