P. Abbott, A clinical classification of the status of the pulp and the root canal system Abou-Rass M and Piccinino M V, The effectiveness of four clinical irrigation methods on the removal of root canal debris. Oral Surg, Aust. Dent. J. Oral Med. Oral Pathol, vol.1, issue.3, pp.52-69, 1982.

M. Ahmad, P. Ford, T. J. Crum, L. Ahmad, M. et al., Ultrasonic debridement of root canals: acoustic streaming and its possible role Ultrasonic debridement of root canals: an insight into the mechanisms involved Ultrasonic debridement of root canals: acoustic cavitation and its relevance Efficacy of a new brushcovered irrigation needle in removing root canal debris: a scanning electron microscopic study, Ando F, [Chemical preparation in endodontic therapy. 2. Various properties of EDTA, phenolsulfonic acid and citric acid]. Aichi Gakuin Daigaku Shigakkai Shi, pp.13-490, 1985.

L. Angker, M. Swain, and N. Kilpatrick, Characterising the micro-mechanical behaviour of the carious dentine of primary teeth using nano-indentation, Journal of Biomechanics, vol.38, issue.7, pp.38-1535, 2005.
DOI : 10.1016/j.jbiomech.2004.07.012

R. Archer, A. Reader, R. Nist, M. Beck, and W. Meyers, An in vivo evaluation of the efficacy of ultrasound after step-back preparation in mandibular molars, Journal of Endodontics, vol.18, issue.11, pp.18-549, 1992.
DOI : 10.1016/S0099-2399(06)81212-4

M. T. Arias-moliz, E. Espigares-rodriguez, and M. Espigares-garcia, Bactericidal activity of phosphoric acid, citric acid, and EDTA solutions against Enterococcus faecalis. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.2, pp.106-84, 2008.

B. Athanassiadis, P. Abbott, and L. Walsh, The use of calcium hydroxide, antibiotics and biocides as antimicrobial medicaments in endodontics, Australian Dental Journal, vol.32, issue.Suppl 3, pp.52-64, 2007.
DOI : 10.1001/archsurg.1996.01430150116021

P. J. Baker, R. T. Evans, R. A. Coburn, and R. J. Genco, Tetracycline and Its Derivatives Strongly Bind to and Are Released From the Tooth Surface in Active Form, Journal of Periodontology, vol.3, issue.10, pp.54-580, 1983.
DOI : 10.1177/00220345740530023001

W. C. Barrette, J. Hannum, D. M. Wheeler, and J. Hurst, General mechanism for the bacterial toxicity of hypochlorous acid: abolition of ATP production, Biochemistry, vol.28, issue.23, pp.28-9172, 1989.
DOI : 10.1021/bi00449a032

B. R. Basrani, S. Manek, R. N. Sodhi, E. Fillery, and A. Manzur, Interaction between Sodium Hypochlorite and Chlorhexidine Gluconate, Journal of Endodontics, vol.33, issue.8, pp.33-966, 2007.
DOI : 10.1016/j.joen.2007.04.001

J. C. Baumgartner, C. M. Brown, C. L. Mader, D. Peters, and J. Shulman, A scanning electron microscopic evaluation of root canal debridement using saline, sodium hypochlorite, and citric acid, Journal of Endodontics, vol.10, issue.11, pp.10-525, 1984.
DOI : 10.1016/S0099-2399(84)80137-5

J. Baumgartner and P. Cuenin, Efficacy of several concentrations of sodium hypochlorite for root canal irrigation, Journal of Endodontics, vol.18, issue.12, pp.18-605, 1992.
DOI : 10.1016/S0099-2399(06)81331-2

J. Baumgartner and A. Ibay, The chemical reactions of irrigants used for root canal debridement, Journal of Endodontics, vol.13, issue.2, pp.13-47, 1987.
DOI : 10.1016/S0099-2399(87)80153-X

J. C. Baumgartner and C. Mader, A scanning electron microscopic evaluation of four root canal irrigation regimens, J. Endod, vol.4, pp.13-147, 1987.

J. C. Baumgartner, J. F. Siqueira, J. Xia, T. Rocas, and I. , Geographical Differences in Bacteria Detected in Endodontic Infections Using Polymerase Chain Reaction, Journal of Endodontics, vol.30, issue.3, pp.30-141, 2004.
DOI : 10.1097/00004770-200403000-00004

G. L. Becker, S. Cohen, and R. Borer, The sequelae of accidentally injecting sodium hypochlorite beyond the root apex Report of a case. Oral Surg, Oral Med. Oral Pathol, vol.4, pp.38-633, 1974.

A. Becking, Complications in the use of sodium hypochlorite during endodontic treatment Report of three cases. Oral Surg, Oral Med. Oral Pathol, vol.3, pp.71-346, 1991.

E. Berutti, R. Marini, and A. Angeretti, Penetration ability of different irrigants into dentinal tubules, Journal of Endodontics, vol.23, issue.12, pp.23-725, 1997.
DOI : 10.1016/S0099-2399(97)80342-1

S. F. Bloomfield and E. Uso, The antibacterial properties of sodium hypochlorite and sodium dichloroisocyanurate as hospital disinfectants, Journal of Hospital Infection, vol.6, issue.1, pp.20-30, 1985.
DOI : 10.1016/S0195-6701(85)80014-1

C. Lambrianidis, T. Kastrinakis, and E. , Irrigant flow within a prepared root canal using various flow rates: a Computational Fluid Dynamics study, Int. Endod. J, vol.2, pp.42-144, 2009.

C. Lambrianidis, T. Kastrinakis, E. Bekiaroglou, and P. , Measurement of pressure and flow rates during irrigation of a root canal ex vivo with three endodontic needles, Int. Endod. J, vol.7, pp.40-504, 2007.

G. H. Bowden and I. Hamilton, Survival of Oral Bacteria, Critical Reviews in Oral Biology & Medicine, vol.9, issue.1, pp.54-85, 1998.
DOI : 10.1902/jop.1990.61.2.75

A. Bystrom and G. Sundqvist, The antibacterial action of sodium hypochlorite and EDTA in 60 cases of endodontic therapy, International Endodontic Journal, vol.78, issue.1, pp.18-35, 1985.
DOI : 10.1016/0030-4220(80)90292-3

A. Bystrom and G. Sundqvist, Bacteriologic evaluation of the effect of 0.5 percent sodium hypochlorite in endodontic therapy. Oral Surg, Oral Med. Oral Pathol, vol.3, pp.55-307, 1983.

M. K. Caliskan, M. Turkun, and S. Alper, Allergy to sodium hypochlorite during root canal therapy: a case report, Int. Endod. J, vol.3, pp.27-163, 1994.

S. Calt and A. Serper, Time-Dependent Effects of EDTA on Dentin Structures, Journal of Endodontics, vol.28, issue.1, pp.28-45, 2002.
DOI : 10.1097/00004770-200201000-00004

G. Caron, Cleaning efficiency of the apical milimeters of curved canals using three diffferent modalities of irrigant activation : an SEM study, 2007.

M. Cergneux, B. Ciucchi, J. M. Dietschi, and J. Holz, The influence of the smear layer on the sealing ability of canal obturation, International Endodontic Journal, vol.10, issue.1, pp.20-228, 1987.
DOI : 10.1038/sj.bdj.4804007

Y. C. Chang, F. M. Huang, K. W. Tai, and M. Chou, The effect of sodium hypochlorite and chlorhexidine on cultured human periodontal ligament cells. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.4, pp.92-446, 2001.

L. De-paz, Redefining the Persistent Infection in Root Canals: Possible Role of Biofilm Communities, Journal of Endodontics, vol.33, issue.6, pp.33-652, 2007.
DOI : 10.1016/j.joen.2006.11.004

H. K. Chng, J. E. Palamara, and H. Messer, Effect of Hydrogen Peroxide and Sodium Perborate on Biomechanical Properties of Human Dentin, Journal of Endodontics, vol.28, issue.2, pp.28-62, 2002.
DOI : 10.1097/00004770-200202000-00003

T. Chow, Mechanical effectiveness of root canal irrigation, Journal of Endodontics, vol.9, issue.11, pp.475-484, 1983.
DOI : 10.1016/S0099-2399(83)80162-9

R. Clarkson and A. J. Moule, Sodium hypochlorite and its use as an endodontic irrigant, Australian Dental Journal, vol.13, issue.3, pp.43-250, 1998.
DOI : 10.1016/S0099-2399(87)80034-1

M. S. Clegg, F. J. Vertucci, C. Walker, M. Belanger, and L. Britto, The Effect of Exposure to Irrigant Solutions on Apical Dentin Biofilms In Vitro, Journal of Endodontics, vol.32, issue.5, pp.32-434, 2006.
DOI : 10.1016/j.joen.2005.07.002

L. G. Coldero, S. Mchugh, D. Mackenzie, and W. Saunders, Reduction in intracanal bacteria during root canal preparation with and without apical enlargement, International Endodontic Journal, vol.20, issue.5, pp.35-437, 2002.
DOI : 10.1016/S0099-2399(06)80067-1

J. W. Costerton, Bacterial Biofilms in Nature and Disease, Annual Review of Microbiology, vol.41, issue.1, pp.41-435, 1987.
DOI : 10.1146/annurev.mi.41.100187.002251

W. T. Cunningham and H. Martin, A scanning electron microscope evaluation of root canal debridement with the endosonic ultrasonic synergistic system. Oral Surg, Oral Med. Oral Pathol, vol.5, pp.53-527, 1982.

W. T. Cunningham, H. Martin, and W. Forrest, Evaluation of root canal debridement by the endosonic ultrasonic synergistic system. Oral Surg, Oral Med. Oral Pathol, vol.4, pp.53-401, 1982.

W. T. Cunningham, H. Martin, G. B. Pelleu, J. Stoops, and D. , A comparison of antimicrobial effectiveness of endosonic and hand root canal therapy. Oral Surg, Oral Med. Oral Pathol, vol.2, pp.54-238, 1982.

M. Cvek and A. Lindvall, External root resorption following bleaching of pulpless teeth with oxygen peroxide, Dental Traumatology, vol.24, issue.2, pp.56-60, 1985.
DOI : 10.3109/00016358109162253

M. Czonstkowsky, E. Wilson, and F. A. Holstein, The smear layer in endodontics, Dent. Clin. North Am, vol.1, pp.34-47, 1990.

D. Lenarda, R. Cadenaro, M. Sbaizero, and O. , Effectiveness of 1 mol L-1 citric acid and 15% EDTA irrigation on smear layer removal, International Endodontic Journal, vol.22, issue.1, pp.33-46, 2000.
DOI : 10.1016/S0099-2399(96)80232-9

S. R. Dotto, R. M. Travassos, E. P. De-oliveira, M. Machado, and J. Martins, Evaluation of ethylenediaminetetraacetic acid (EDTA) solution and gel for smear layer removal, Australian Endodontic Journal, vol.28, issue.2, pp.33-62, 2007.
DOI : 10.1016/S0099-2399(06)81296-3

E. Drenkard and F. Ausubel, Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation, Nature, vol.59, issue.6882, pp.416-740, 2002.
DOI : 10.1016/0378-1119(91)90016-5

T. R. Dunavant, J. D. Regan, G. N. Glickman, E. Solomon, and A. Honeyman, Comparative Evaluation of Endodontic Irrigants against Enterococcus faecalis Biofilms, Journal of Endodontics, vol.32, issue.6, pp.32-527, 2006.
DOI : 10.1016/j.joen.2005.09.001

N. , L. E. Kolokuris, I. Beltes, and P. , Long-term evaluation of the influence of smear layer removal on the sealing ability of different sealers, J. Endod, vol.2, pp.25-123, 1999.

D. G. Ehrich, J. D. Brian, J. Walker, and W. , Sodium hypochlorite accident: Inadvertent injection into the maxillary sinus, Journal of Endodontics, vol.19, issue.4, pp.19-180, 1993.
DOI : 10.1016/S0099-2399(06)80684-9

E. Endodontology, Consensus report of the European Society of Endodontology on quality guidelines for endodontic treatment, Int. Endod. J, vol.3, pp.27-115, 1994.

E. Ercan, M. Dalli, and C. Dulgergil, In vitro assessment of the effectiveness of chlorhexidine gel and calcium hydroxide paste with chlorhexidine against Enterococcus faecalis and Candida albicans, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, vol.102, issue.2, pp.102-129, 2006.
DOI : 10.1016/j.tripleo.2006.02.022

P. T. Esposito and C. Cunningham, A comparison of canal preparation with nickeltitanium and stainless steel instruments, J. Endod, vol.4, pp.173-179, 1995.

M. D. Evans, J. C. Baumgartner, S. U. Khemaleelakul, and T. Xia, Efficacy of Calcium Hydroxide: Chlorhexidine Paste as an Intracanal Medication in Bovine Dentin, Journal of Endodontics, vol.29, issue.5, pp.29-338, 2003.
DOI : 10.1097/00004770-200305000-00005

D. B. Ferguson, J. T. Marley, and G. Hartwell, The Effect of Chlorhexidine Gluconate as an Endodontic Irrigant on the Apical Seal: Long-term Results, Journal of Endodontics, vol.29, issue.2, pp.29-91, 2003.
DOI : 10.1097/00004770-200302000-00001

H. M. Fogel and D. Pashley, Dentin permeability: Effects of endodontic procedures on root slabs, Journal of Endodontics, vol.16, issue.9, pp.16-442, 1990.
DOI : 10.1016/S0099-2399(06)81888-1

A. Fouad, PCR-Based Identification of Bacteria Associated with Endodontic Infections, Journal of Clinical Microbiology, vol.40, issue.9, pp.40-3223, 2002.
DOI : 10.1128/JCM.40.9.3223-3231.2002

H. G. Fromme, R. Guttzeit, and H. Riedel, Experimental studies on the question of mechanical and chemical root canal preparation and on the adhesiveness of root canal filling materials], Dtsch. Zahnarztl. Z, vol.9, pp.25-865, 1970.

R. Garberoglio and C. Becce, Smear layer removal by root canal irrigants. A comparative scanning electron microscopic study. Oral Surg, Oral Med. Oral Pathol, vol.3, pp.78-359, 1994.

R. Garberoglio and M. Brannstrom, Scanning electron microscopic investigation of human dentinal tubules, Archives of Oral Biology, vol.21, issue.6, pp.355-62, 1976.
DOI : 10.1016/S0003-9969(76)80003-9

A. Gatot, J. Arbelle, A. Leiberman, and I. Yanai-inbar, Effects of sodium hypochlorite on soft tissues after its inadvertent injection beyond the root apex, Journal of Endodontics, vol.17, issue.11, pp.17-573, 1991.
DOI : 10.1016/S0099-2399(06)81725-5

B. H. Gettleman, H. Messer, and M. Eldeeb, Adhesion of sealer cements to dentin with and without the smear layer, Journal of Endodontics, vol.17, issue.1, pp.17-32, 1991.
DOI : 10.1016/S0099-2399(07)80155-5

P. Gilbert, J. Das, and I. Foley, Biofilm Susceptibility to Antimicrobials, Advances in Dental Research, vol.46, issue.1, pp.160-167, 1997.
DOI : 10.1128/AAC.39.2.507

F. Goldberg and A. Abramovich, Analysis of the effect of EDTAC on the dentinal walls of the root canal, Journal of Endodontics, vol.3, issue.3, pp.101-106, 1977.
DOI : 10.1016/S0099-2399(77)80203-3

L. B. Goldman, M. Goldman, J. H. Kronman, and P. Lin, The efficacy of several irrigating solutions for endodontics: A scanning electron microscopic study, Oral Surgery, Oral Medicine, Oral Pathology, vol.52, issue.2, pp.52-197, 1981.
DOI : 10.1016/0030-4220(81)90319-4

B. Gomes, In vitro antimicrobial activity of several concentrations of sodium hypochlorite and chlorhexidine gluconate in the elimination of Enterococcus faecalis, International Endodontic Journal, vol.9, issue.6, pp.34-424, 2001.
DOI : 10.1111/j.1600-9657.1993.tb00280.x

B. P. Gomes, J. Lilley, and D. Drucker, Clinical significance of dental root canal microflora, Journal of Dentistry, vol.24, issue.1-2, pp.24-25, 1996.
DOI : 10.1016/0300-5712(95)00042-9

B. Gomes, Evaluation of time required for recontamination of coronally sealed canals medicated with calcium hydroxide and chlorhexidine, International Endodontic Journal, vol.46, issue.9, pp.36-604, 2003.
DOI : 10.1046/j.1365-2591.2002.00529.x

B. Gomes, Effectiveness of 2% chlorhexidine gel and calcium hydroxide against Enterococcus faecalis in bovine root dentine in vitro, International Endodontic Journal, vol.98, issue.4, pp.36-267, 2003.
DOI : 10.1046/j.1365-2591.1999.00237.x

A. Goodman, A. Reader, M. Beck, R. Melfi, and W. Meyers, An in vitro comparison of the efficacy of the stepback technique versus a step-back/ultrasonic technique in human mandibular molars, Journal of Endodontics, vol.11, issue.6, pp.249-56, 1985.
DOI : 10.1016/S0099-2399(85)80180-1

S. Grandini, P. Balleri, and M. Ferrari, Evaluation of Glyde File Prep in Combination with Sodium Hypochlorite as a Root Canal Irrigant, Journal of Endodontics, vol.28, issue.4, pp.28-300, 2002.
DOI : 10.1097/00004770-200204000-00010

M. Grawehr, B. Sener, T. Waltimo, and M. Zehnder, Interactions of ethylenediamine tetraacetic acid with sodium hypochlorite in aqueous solutions, International Endodontic Journal, vol.21, issue.6, pp.36-411, 2003.
DOI : 10.1067/moe.2002.128961

L. Gu, Review of Contemporary Irrigant Agitation Techniques and Devices, Journal of Endodontics, vol.35, issue.6, pp.35-791, 2009.
DOI : 10.1016/j.joen.2009.03.010

K. Gulabivala, B. Patel, G. Evans, and Y. Ng, Effects of mechanical and chemical procedures on root canal surfaces, Endodontic Topics, vol.13, issue.1, pp.10-103, 2005.
DOI : 10.1046/j.1365-2591.2002.00541.x

H. K. Siren, E. K. Waltimo, T. M. Orstavik, D. Haapasalo, and M. , Inactivation of local root canal medicaments by dentine: an in vitro study, Int. Endod. J, vol.2, pp.33-126, 2000.

M. Haapasalo, U. Endal, H. Zandi, M. , and J. , Eradication of endodontic infection by instrumentation and irrigation solutions, Endodontic Topics, vol.19, issue.21, pp.10-77, 2005.
DOI : 10.1111/j.0143-2885.2004.00785.x

M. Endal, U. Zandi, H. , M. Coil, and J. , Eradication of endodontic infection by instrumentation and irrigation solutions, Endodontic Topics, vol.1, pp.10-77, 2005.

F. Hahn and F. Reygadas, Demineralization of Hard Tissues, Science, vol.114, issue.2966, pp.114-462, 1951.
DOI : 10.1126/science.114.2966.462

J. Haidet, A. Reader, M. Beck, and W. Meyers, An in vivo comparison of the step-back technique versus a step-back/ultrasonic technique in human mandibular molars, Journal of Endodontics, vol.15, issue.5, pp.15-195, 1989.
DOI : 10.1016/S0099-2399(89)80234-1

G. W. Harrington and E. Natkin, External resorption associated with bleaching of pulpless teeth, Journal of Endodontics, vol.5, issue.11, pp.344-352, 1979.
DOI : 10.1016/S0099-2399(79)80091-6

I. Heling and N. Chandler, Antimicrobial effect of irrigant combinations within dentinal tubules, International Endodontic Journal, vol.31, issue.1, pp.31-39, 1998.
DOI : 10.1046/j.1365-2591.1998.t01-1-00124.x

I. Heling, I. Rotstein, T. Dinur, Y. Szwec-levine, and D. Steinberg, Bactericidal and Cytotoxic Effects of Sodium Hypochlorite and Sodium Dichloroisocyanurate Solutions In Vitro, Journal of Endodontics, vol.27, issue.4, pp.27-278, 2001.
DOI : 10.1097/00004770-200104000-00009

J. W. Herrmann and R. Heicht, Complications in therapeutic use of sodium hypochlorite, Journal of Endodontics, vol.5, issue.5, p.160, 1979.
DOI : 10.1016/S0099-2399(79)80039-4

N. Horiba, Y. Maekawa, T. Matsumoto, and H. Nakamura, A study of the distribution of endotoxin in the dentinal wall of infected root canals, Journal of Endodontics, vol.16, issue.7, pp.16-331, 1990.
DOI : 10.1016/S0099-2399(06)81944-8

T. L. Hottel, N. Y. Refai, and J. Jones, A comparison of the effects of three chelating agents on the root canals of extracted human teeth, Journal of Endodontics, vol.25, issue.11, pp.25-716, 1999.
DOI : 10.1016/S0099-2399(99)80115-0

T. Y. Huang, K. Gulabivala, and Y. Ng, A bio-molecular film ex-vivo model to evaluate the influence of canal dimensions and irrigation variables on the efficacy of irrigation, International Endodontic Journal, vol.17, issue.0, pp.41-60, 2008.
DOI : 10.1016/S1079-2104(05)80134-9

M. Hulsmann and W. Hahn, Complications during root canal irrigation - literature review and case reports, International Endodontic Journal, vol.42, issue.3, pp.33-186, 2000.
DOI : 10.1016/0030-4220(76)90107-9

M. Hulsmann, M. Heckendorff, and A. Lennon, Chelating agents in root canal treatment: mode of action and indications for their use, International Endodontic Journal, vol.2, issue.Suppl. 1, pp.36-810, 2003.
DOI : 10.1177/00220345730520060501

T. A. Ingram, Response of the human eye to accidental exposure to sodium hypochlorite, Journal of Endodontics, vol.16, issue.5, pp.16-235, 1990.
DOI : 10.1016/S0099-2399(06)81678-X

S. A. Jensen, T. L. Walker, J. W. Hutter, and B. Nicoll, Comparison of the cleaning efficacy of passive sonic activation and passive ultrasonic activation after hand instrumentation in molar root canals, Journal of Endodontics, vol.25, issue.11, pp.25-735, 1999.
DOI : 10.1016/S0099-2399(99)80120-4

E. Joffe, Complication during root canal therapy following accidental extrusion of sodium hypochlorite through the apical foramen, Gen. Dent, vol.6, pp.39-460, 1991.

F. H. Kahn, P. Rosenberg, and J. Gliksberg, An in vitro evaluation of the irrigating characteristics of ultrasonic and subsonic handpieces and irrigating needles and probes, Journal of Endodontics, vol.21, issue.5, pp.21-277, 1995.
DOI : 10.1016/S0099-2399(06)80998-2

S. Kakehashi, H. R. Stanley, and R. Fitzgerald, The Effects of Surgical Exposures of Dental Pulps in Germ-Free and Conventional Laboratory Rats. Oral Surg, Oral Med. Oral Pathol, pp.20-340, 1965.

A. Kaufman and K. S. , Hypersensitivity to sodium hypochlorite, Journal of Endodontics, vol.15, issue.5, pp.15-224, 1989.
DOI : 10.1016/S0099-2399(89)80241-9

C. Kavanagh and J. Taylor, Inadvertent injection of sodium hypochlorite into the maxillary sinus, British Dental Journal, vol.185, issue.7, pp.185-336, 1998.
DOI : 10.1038/sj.bdj.4809809

D. M. Keir, E. S. Senia, and S. Montgomery, Effectiveness of a brush in removing postinstrumentation canal debris, Journal of Endodontics, vol.16, issue.7, pp.16-323, 1990.
DOI : 10.1016/S0099-2399(06)81942-4

W. A. Kennedy, W. A. Walker, and R. Gough, Smear layer removal effects on apical leakage, Journal of Endodontics, vol.12, issue.1, pp.12-21, 1986.
DOI : 10.1016/S0099-2399(86)80277-1

A. A. Khademi, Z. Mohammadi, and A. Havaee, Evaluation of the antibacterial substantivity of several intra-canal agents, Australian Endodontic Journal, vol.96, issue.3, pp.32-112, 2006.
DOI : 10.1097/00004770-200306000-00009

Y. Kinomoto, D. L. Carnes, J. Ebisu, and S. , Cytotoxicity of Intracanal Bleaching Agents on Periodontal Ligament Cells In Vitro, Journal of Endodontics, vol.27, issue.9, pp.27-574, 2001.
DOI : 10.1097/00004770-200109000-00005

P. Krasner and H. J. Rankow, Anatomy of the Pulp-Chamber Floor, Journal of Endodontics, vol.30, issue.1, pp.30-35, 2004.
DOI : 10.1097/00004770-200401000-00002

A. B. Krautheim, T. H. Jermann, and A. J. Bircher, Chlorhexidine anaphylaxis: case report and review of the literature, Contact Dermatitis, vol.304, issue.3, pp.50-113, 2004.
DOI : 10.1136/bmj.315.7111.785

L. Goff, A. Bunetel, L. Mouton, C. Bonnaure-mallet, and M. , Evaluation of root canal bacteria and their antimicrobial susceptibility in teeth with necrotic pulp, Oral Microbiology and Immunology, vol.11, issue.5, pp.12-318, 1997.
DOI : 10.1016/S0099-2399(06)81409-3

S. J. Lee, M. Wu, and P. Wesselink, The effectiveness of syringe irrigation and ultrasonics to remove debris from simulated irregularities within prepared root canal walls, International Endodontic Journal, vol.79, issue.10, pp.37-672, 2004.
DOI : 10.1046/j.1365-2591.2003.00646.x

S. J. Lee, M. Wu, and P. Wesselink, The efficacy of ultrasonic irrigation to remove artificially placed dentine debris from different-sized simulated plastic root canals, International Endodontic Journal, vol.79, issue.9, pp.37-607, 2004.
DOI : 10.1067/moe.2000.106344

M. Leonardo, In vivo antimicrobial activity of 2% chlorhexidine used as a root canal irrigating solution, Journal of Endodontics, vol.25, issue.3, pp.25-167, 1999.
DOI : 10.1016/S0099-2399(99)80135-6

K. Lester and A. Boyde, Scanning electron microscopy of instrumented, irrigated and filled root canals, British Dental Journal, vol.143, issue.11, pp.143-359, 1977.
DOI : 10.1038/sj.bdj.4804007

R. Lev, A. Reader, M. Beck, and W. Meyers, An in vitro comparison of the step-back technique versus a step-back/ultrasonic technique for 1 and 3 minutes, Journal of Endodontics, vol.13, issue.11, pp.13-523, 1987.
DOI : 10.1016/S0099-2399(87)80031-6

T. S. Lim, T. Y. Wee, M. Y. Choi, W. C. Koh, and V. Sae-lim, Light and scanning electron microscopic evaluation of Glyde File Prep in smear layer removal, Int. Endod. J, vol.5, pp.36-336, 2003.

R. A. Lindemann, W. R. Hume, and R. Wolcott, Dentin permeability and pulpal response to EDTA, The Journal of Prosthetic Dentistry, vol.53, issue.3, pp.53-341, 1985.
DOI : 10.1016/0022-3913(85)90506-2

E. Liolios, N. Economides, S. Parissis-messimeris, and A. Boutsioukis, The effectiveness of three irrigating solutions on root canal cleaning after hand and mechanical preparation, International Endodontic Journal, vol.9, issue.1, pp.30-51, 1997.
DOI : 10.1016/S0099-2399(83)80032-6

D. A. Loel, Use of acid cleanser in endodontic therapy, The Journal of the American Dental Association, vol.90, issue.1, pp.90-148, 1975.
DOI : 10.14219/jada.archive.1975.0010

R. Love, Invasion of dentinal tubules by root canal bacteria, Endodontic Topics, vol.24, issue.32, pp.52-65, 2004.
DOI : 10.1034/j.1399-302X.2003.00059.x

P. J. Lumley, A. D. Walmsley, R. Walton, and J. W. Rippin, Effect of precurving endosonic files on the amount of debris and smear layer remaining in curved root canals, Journal of Endodontics, vol.18, issue.12, pp.18-616, 1992.
DOI : 10.1016/S0099-2399(06)81333-6

R. Lynne, In Vitro Antimicrobial Activity of Various Medication Preparations on E. faecalis in Root Canal Dentin, Journal of Endodontics, vol.29, issue.3, pp.29-187, 2003.
DOI : 10.1097/00004770-200303000-00006

L. F. Machado-silveiro, S. Gonzalez-lopez, and M. Gonzalez-rodriguez, Decalcification of root canal dentine by citric acid, EDTA and sodium citrate, International Endodontic Journal, vol.9, issue.6, pp.37-365, 2004.
DOI : 10.1016/0022-3913(81)90243-2

C. L. Mader, J. C. Baumgartner, and D. Peters, Scanning electron microscopic investigation of the smeared layer on root canal walls, Journal of Endodontics, vol.10, issue.10, pp.10-477, 1984.
DOI : 10.1016/S0099-2399(84)80204-6

C. F. Malheiros, M. M. Marques, and G. Gavini, In Vitro Evaluation of the Cytotoxic Effects of Acid Solutions Used as Canal Irrigants, Journal of Endodontics, vol.31, issue.10, pp.31-746, 2005.
DOI : 10.1097/01.don.0000157994.49432.67

H. Martin and W. Cunningham, An evaluation of postoperative pain incidence following endosonic and conventional root canal therapy. Oral Surg, Oral Med. Oral Pathol, vol.1, pp.54-74, 1982.

H. Martin, W. T. Cunningham, J. Norris, and W. Cotton, Ultrasonic versus hand filing of dentin: a quantitative study. Oral Surg, Oral Med. Oral Pathol, vol.1, pp.49-79, 1980.

C. R. Masillamoni, J. D. Kettering, and M. Torabinejad, The biocompatibility of some root canal medicaments and irrigants, International Endodontic Journal, vol.11, issue.2, pp.14-115, 1981.
DOI : 10.1016/0030-4220(70)90472-X

B. A. Matis, H. N. Mousa, M. A. Cochran, and G. Eckert, Clinical evaluation of bleaching agents of different concentrations, Quintessence Int, vol.5, pp.31-303, 2000.

D. Mccomb and D. Smith, A preliminary scanning electron microscopic study of root canals after endodontic procedures, Journal of Endodontics, vol.1, issue.7, pp.238-280, 1975.
DOI : 10.1016/S0099-2399(75)80226-3

G. Mcdonnell and A. Russell, Antiseptics and disinfectants: activity, action, and resistance, Clin. Microbiol. Rev, vol.1, pp.12-147, 1999.

S. Mcgill, K. Gulabivala, N. Mordan, and Y. Ng, ) determined by removal of a collagen ???bio-molecular film??? from an ex vivo model, International Endodontic Journal, vol.362, issue.7, pp.41-602, 2008.
DOI : 10.1098/rsta.2003.1356

I. Mello, C. R. Robazza, J. Antoniazzi, and J. Coil, Influence of different volumes of EDTA for final rinse on smear layer removal. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.5, pp.106-146, 2008.

I. A. Mjor and I. Nordahl, The density and branching of dentinal tubules in human teeth, Archives of Oral Biology, vol.41, issue.5, pp.41-401, 1996.
DOI : 10.1016/0003-9969(96)00008-8

I. A. Mjor, O. Sveen, and K. Heyeraas, Normal structure and physiology, in Pulp-dentin Biology in Restorative Dentistry, pp.1-22, 2002.

Z. Mohammadi and P. Abbott, The properties and applications of chlorhexidine in endodontics, International Endodontic Journal, vol.100, issue.Suppl, pp.42-288, 2009.
DOI : 10.1159/000210865

A. Molander, C. Reit, G. Dahlen, and T. Kvist, Microbiological status of root-filled teeth with apical periodontitis, International Endodontic Journal, vol.31, issue.1, pp.31-32, 1998.
DOI : 10.1046/j.1365-2591.1998.t01-1-00111.x

A. J. Moller, Microbiological examination of root canals and periapical tissues of human teeth. Methodological studies, Odontol. Tidskr, vol.5, pp.741-380, 1966.

A. J. Moller, L. Fabricius, G. Dahlen, A. E. Ohman, and G. Heyden, Influence on periapical tissues of indigenous oral bacteria and necrotic pulp tissue in monkeys. Scand, J. Dent. Res, vol.6, pp.89-475, 1981.

N. Naenni, K. Thoma, and M. Zehnder, Soft Tissue Dissolution Capacity of Currently Used and Potential Endodontic Irrigants, Journal of Endodontics, vol.30, issue.11, pp.30-785, 2004.
DOI : 10.1097/00004770-200411000-00009

P. Nair, On the causes of persistent apical periodontitis: a review, International Endodontic Journal, vol.62, issue.2, pp.39-249, 2006.
DOI : 10.1016/0030-4220(82)90196-7

M. S. "-o-'connell, L. A. Morgan, W. J. Beeler, and J. Baumgartner, A comparative study of smear layer removal using different salts of EDTA, J. Endod, vol.12, pp.26-739, 2000.

L. A. Okino, E. L. Siqueira, M. Santos, A. Bombana, and J. A. Figueiredo, Dissolution of pulp tissue by aqueous solution of chlorhexidine digluconate and chlorhexidine digluconate gel, International Endodontic Journal, vol.23, issue.Suppl. 12, pp.37-38, 2004.
DOI : 10.14219/jada.archive.1936.0200

J. B. Park and N. Park, Effect of chlorhexidine on the in vitro and in vivo herpes simplex virus infection. Oral Surg, Oral Med. Oral Pathol, vol.2, pp.67-149, 1989.

D. Pashley, Smear layer: overview of structure and function, Proc. Finn, pp.88-215, 1992.

D. Pashley, Smear layer: physiological considerations, Oper. Dent, issue.3, pp.13-29, 1984.

E. L. Pashley, N. L. Birdsong, K. Bowman, and D. Pashley, Cytotoxic effects of NaOCl on vital tissue, Journal of Endodontics, vol.11, issue.12, pp.525-533, 1985.
DOI : 10.1016/S0099-2399(85)80197-7

S. Patterson, In vivo and in vitro studies of the effect of the disodium slat of ethylenediamine tetra-acetate on human dentine and its endodontic implications. Oral Surg, Oral Med. Oral Pathol, pp.16-83, 1963.

H. Pawlicka, D. Piatkowska, and G. Hajdukiewicz, Effectiveness of cleansing agents in root canal preparation. A scanning electron microscopy study], Stomatol. DDR, vol.9, pp.31-684, 1981.

V. Perez, M. Cardenas, and U. Planells, The possible role of pH changes during EDTA deminaralization of teeth. Oral Surg, Oral Med. Oral Pathol, pp.68-220, 1989.

M. Perez-heredia, C. M. Ferrer-luque, and M. Gonzalez-rodriguez, The Effectiveness of Different Acid Irrigating Solutions in Root Canal Cleaning After Hand and Rotary Instrumentation, Journal of Endodontics, vol.32, issue.10, pp.32-993, 2006.
DOI : 10.1016/j.joen.2006.05.016

O. A. Peters, C. Boessler, and M. Zehnder, Effect of liquid and paste-type lubricants on torque values during simulated rotary root canal instrumentation, International Endodontic Journal, vol.113, issue.4, pp.38-223, 2005.
DOI : 10.14219/jada.archive.1936.0200

O. A. Peters, K. Schonenberger, and A. Laib, Effects of four Ni-Ti preparation techniques on root canal geometry assessed by micro computed tomography, International Endodontic Journal, vol.28, issue.3, pp.34-221, 2001.
DOI : 10.1097/00004770-200004000-00003

W. Pitt, Removal of oral biofilm by sonic phenomena, Am. J. Dent, vol.5, pp.18-345, 2005.

I. Portenier, T. Waltimo, D. Orstavik, and M. Haapasalo, Killing of Enterococcus faecalis by MTAD and Chlorhexidine Digluconate with or without Cetrimide in the Presence or Absence of Dentine Powder or BSA, Journal of Endodontics, vol.32, issue.2, pp.32-138, 2006.
DOI : 10.1016/j.joen.2005.10.027

R. J. Pugh, A. C. Goerig, C. G. Glaser, and W. Luciano, A comparison of four endodontic vibratory systems, Gen. Dent, vol.4, pp.37-296, 1989.

C. Radcliffe, Antimicrobial activity of varying concentrations of sodium hypochlorite on the endodontic microorganisms Actinomyces israelii, A. naeslundii, Candida albicans and Enterococcus faecalis, International Endodontic Journal, vol.9, issue.7, pp.37-438, 2004.
DOI : 10.1016/S1079-2104(98)90404-8

O. W. Reeder, J. Walton, R. E. Livingston, M. J. Pashley, and D. , Dentin Permeability: Determinants of Hydraulic Conductance, Journal of Dental Research, vol.20, issue.2, pp.57-187, 1978.
DOI : 10.1016/S0003-9969(76)80003-9

E. Reeh and H. Messer, Long-term paresthesia following inadvertent forcing of sodium hypochlorite through perforation in maxillary incisor, Dental Traumatology, vol.6, issue.4, pp.200-203, 1989.
DOI : 10.1016/0030-4220(80)90292-3

M. Richman, The use of ultrasonics in root canal therapy nd root resection, J. Med, vol.12, pp.12-20, 1957.

J. Siqueira and J. , Detection of novel oral species and phylotypes in symptomatic endodontic infections including abscesses, FEMS Microbiol Lett, vol.2, pp.250-279, 2005.

I. N. Rocas, J. F. Siqueira, J. Santos, and K. , Association of Enterococcus faecalis With Different Forms of Periradicular Diseases, Journal of Endodontics, vol.30, issue.5, pp.30-315, 2004.
DOI : 10.1097/00004770-200405000-00004

I. N. Rocas, J. F. Siqueira, J. Santos, K. Coelho, and A. , Red complex" (Bacteroides forsythus, Porphyromonas gingivalis, and Treponema denticola) in endodontic infections: a molecular approach. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.4, pp.91-468, 2001.

S. Rosenthal, L. Spangberg, and K. Safavi, Chlorhexidine substantivity in root canal dentin. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.4, pp.98-488, 2004.

A. Russell and M. Day, Antibacterial activity of chlorhexidine, Journal of Hospital Infection, vol.25, issue.4, pp.25-229, 1993.
DOI : 10.1016/0195-6701(93)90109-D

C. L. Sabala and S. Powell, Sodium hypochlorite injection into periapical tissues, Journal of Endodontics, vol.15, issue.10, pp.15-490, 1989.
DOI : 10.1016/S0099-2399(89)80031-7

R. A. Sabins, J. Johnson, and J. W. Hellstein, A Comparison of the Cleaning Efficacy of Short-Term Sonic and Ultrasonic Passive Irrigation after Hand Instrumentation in Molar Root Canals, Journal of Endodontics, vol.29, issue.10, pp.29-674, 2003.
DOI : 10.1097/00004770-200310000-00016

M. F. Scelza, J. H. Antoniazzi, and P. Scelza, Efficacy of final irrigation--a scanning electron microscopic evaluation, J. Endod, vol.6, pp.26-355, 2000.

E. Schafer and R. Lau, Comparison of cutting efficiency and instrumentation of curved canals with nickel-titanium and stainless-steel instruments, Journal of Endodontics, vol.25, issue.6, pp.25-427, 1999.
DOI : 10.1016/S0099-2399(99)80272-6

J. Segura, EDTA inhibits in vitro substrate adherence capacity of macrophages: Endodontic implications, Journal of Endodontics, vol.23, issue.4, pp.23-205, 1997.
DOI : 10.1016/S0099-2399(97)80046-5

J. Segura, The disodium salt of EDTA inhibits the binding of vasoactive intestinal peptide to macrophage membranes: Endodontic implications, Journal of Endodontics, vol.22, issue.7, pp.22-337, 1996.
DOI : 10.1016/S0099-2399(96)80213-5

B. H. Sen, B. Piskin, and T. Demirci, Observation of bacteria and fungi in infected root canals and dentinal tubules by SEM, Dental Traumatology, vol.89, issue.1, pp.6-9, 1995.
DOI : 10.1177/00220345870660081801

B. H. Sen, K. E. Safavi, and L. Spangberg, Antifungal effects of sodium hypochlorite and chlorhexidine in root canals, J. Endod, vol.4, pp.25-235, 1999.

S. Shabahang and M. Torabinejad, Effect of MTAD on Enterococcus faecaliscontaminated root canals of extracted human teeth, J. Endod, vol.9, pp.29-576, 2003.

A. Shiozawa, Characterization of Reactive Oxygen Species Generated from the Mixture of NaClO and H2O2 Used as Root Canal Irrigants, Journal of Endodontics, vol.26, issue.1, pp.26-37, 2000.
DOI : 10.1097/00004770-200001000-00003

J. F. Siqueira and J. , Aetiology of root canal treatment failure: why well-treated teeth can fail, International Endodontic Journal, vol.54, issue.1, pp.34-35, 2001.
DOI : 10.1016/0030-4220(82)90196-7

J. F. Siqueira, J. De-uzeda, and M. , Intracanal medicaments: Evaluation of the antibacterial effects of chlorhexidine, metronidazole, and calcium hydroxide associated with three vehicles, Journal of Endodontics, vol.23, issue.3, pp.23-167, 1997.
DOI : 10.1016/S0099-2399(97)80268-3

J. F. Siqueira, J. Rocas, and I. , Clinical Implications and Microbiology of Bacterial Persistence after Treatment Procedures, Journal of Endodontics, vol.34, issue.11, pp.34-1291, 2008.
DOI : 10.1016/j.joen.2008.07.028

J. F. Siqueira, J. Rocas, and I. , Pseudoramibacter alactolyticus in primary endodontic infections, J. Endod, vol.11, pp.29-735, 2003.

J. F. Siqueira, J. Rocas, and I. , Treponema species associated with abscesses of endodontic origin, Oral Microbiology and Immunology, vol.37, issue.5, pp.19-336, 2004.
DOI : 10.1067/moe.2001.118620

J. F. Siqueira, J. Rocas, and I. , Uncultivated Phylotypes and Newly Named Species Associated with Primary and Persistent Endodontic Infections, Journal of Clinical Microbiology, vol.43, issue.7, pp.43-3314, 2005.
DOI : 10.1128/JCM.43.7.3314-3319.2005

J. F. Siqueira, J. Sen, and B. , Fungi in endodontic infections. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.5, pp.97-632, 2004.

J. F. Siqueira, I. Y. Jung, I. Rocas, and C. Lee, Differences in prevalence of selected bacterial species in primary endodontic infections from two distinct geographic locations, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, vol.99, issue.5, pp.99-641, 2005.
DOI : 10.1016/j.tripleo.2004.07.009

J. F. Siqueira, A. G. Machado, R. M. Silveira, H. Lopes, and M. Uzeda, Evaluation of the effectiveness of sodium hypochlorite used with tree irrigation methods in the elimination of Enterococcus faecalis from the root canal, in vitro, Int. Endod. J, vol.4, pp.30-279, 1997.

L. M. Sreebny and G. Nikiforuk, Demineralization of Hard Tissues by Organic Chelating Agents, Science, vol.113, issue.2941, pp.113-2941, 1951.
DOI : 10.1126/science.113.2941.560

D. E. Stamos, E. M. Sadeghi, G. C. Haasch, and H. Gerstein, An in vitro comparison study to quantitate the debridement ability of hand, sonic, and ultrasonic instrumentation, Journal of Endodontics, vol.13, issue.9, pp.13-434, 1987.
DOI : 10.1016/S0099-2399(87)80061-4

P. Stewart and J. W. Costerton, Antibiotic resistance of bacteria in biofilms, The Lancet, vol.358, issue.9276, pp.358-135, 2001.
DOI : 10.1016/S0140-6736(01)05321-1

G. Sundqvist, Associations between microbial species in dental root canal infections, Oral Microbiology and Immunology, vol.66, issue.5, pp.257-62, 1992.
DOI : 10.1016/0030-4220(80)90312-6

G. Sundqvist, D. Figdor, S. Persson, and U. Sjogren, Microbiologic analysis of teeth with failed endodontic treatment and the outcome of conservative re-treatment. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.1, pp.85-86, 1998.

T. A. Svec and J. Harrison, Chemomechanical removal of pulpal and dentinal debris with sodium hypochlorite and hydrogen peroxide vs normal saline solution, Journal of Endodontics, vol.3, issue.2, pp.49-53, 1977.
DOI : 10.1016/S0099-2399(77)80015-0

G. Svensater and G. Bergenholtz, Biofilms in endodontic infections, Endodontic Topics, vol.14, issue.1, pp.27-36, 2004.
DOI : 10.1046/j.1365-2591.2001.00392.x

G. Svensater, B. Sjogreen, and I. Hamilton, Multiple stress responses in Streptococcus mutans and the induction of general and stress-specific proteins, Microbiology, vol.47, issue.1, pp.146-107, 2000.
DOI : 10.1146/annurev.mi.47.100193.001541

N. Symons, A histochemical study of the secondary cartilage of the mandibular condyle in the rat, Archives of Oral Biology, vol.10, issue.4, pp.579-84, 1965.
DOI : 10.1016/0003-9969(65)90003-8

F. M. Tatnall, I. Leigh, and J. Gibson, Comparative Study of Antiseptic Toxicity on Basal Keratinocytes, Transformed Human Keratinocytes and Fibroblasts, Skin Pharmacology and Physiology, vol.3, issue.3, pp.157-63, 1990.
DOI : 10.1159/000210865

M. Torabinejad, Y. Cho, A. A. Khademi, L. K. Bakland, and S. Shabahang, The Effect of Various Concentrations of Sodium Hypochlorite on the Ability of MTAD to Remove the Smear Layer, Journal of Endodontics, vol.29, issue.4, pp.29-233, 2003.
DOI : 10.1097/00004770-200304000-00001

M. Torabinejad, R. Handysides, A. A. Khademi, and L. Bakland, Clinical implications of the smear layer in endodontics: a review. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.6, pp.94-658, 2002.

M. Torabinejad, A New Solution for the Removal of the Smear Layer, Journal of Endodontics, vol.29, issue.3, pp.29-170, 2003.
DOI : 10.1097/00004770-200303000-00002

M. Torabinejad, S. Shabahang, R. Aprecio, and J. Kettering, The Antimicrobial Effect of MTAD: An In Vitro Investigation, Journal of Endodontics, vol.29, issue.6, pp.29-400, 2003.
DOI : 10.1097/00004770-200306000-00005

L. Tronstad, F. Barnett, L. Schwartzben, and P. Frasca, Effectiveness and safety of a sonic vibratory endodontic instrument, Dental Traumatology, vol.1, issue.2, pp.69-76, 1985.
DOI : 10.1016/0030-4220(82)90350-4

L. W. Der-sluis, G. Gambarini, M. Wu, and P. Wesselink, The influence of volume, type of irrigant and flushing method on removing artificially placed dentine debris from the apical root canal during passive ultrasonic irrigation, International Endodontic Journal, vol.27, issue.6, pp.39-472, 2006.
DOI : 10.1046/j.1365-2591.2001.00361.x

L. W. Der-sluis, M. Versluis, M. Wu, and P. Wesselink, Passive ultrasonic irrigation of the root canal: a review of the literature, International Endodontic Journal, vol.6, issue.6, pp.40-415, 2007.
DOI : 10.1046/j.1365-2591.2003.00646.x

F. J. Vertucci, Root canal anatomy of the human permanent teeth, Oral Surgery, Oral Medicine, Oral Pathology, vol.58, issue.5, pp.58-589, 1984.
DOI : 10.1016/0030-4220(84)90085-9

F. J. Vertucci, Root canal morphology and its relationship to endodontic procedures, Endodontic Topics, vol.25, issue.1, pp.3-29, 2005.
DOI : 10.1097/00004770-200205000-00008

M. Vianna, In vitro evaluation of the antimicrobial activity of chlorhexidine and sodium hypochlorite. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.1, pp.97-79, 2004.

N. Vivacqua-gomes, Influence of irrigants on the coronal microleakage of laterally condensed gutta-percha root fillings, International Endodontic Journal, vol.9, issue.9, pp.35-791, 2002.
DOI : 10.1016/S0099-2399(83)80032-6

T. L. Walker and C. Del-rio, Histological evaluation of ultrasonic and sonic instrumentation of curved root canals, Journal of Endodontics, vol.15, issue.2, pp.15-49, 1989.
DOI : 10.1016/S0099-2399(89)80108-6

T. L. Walker and C. Del-rio, Histological evaluation of ultrasonic debridement comparing sodium hypochlorite and water, Journal of Endodontics, vol.17, issue.2, pp.17-66, 1991.
DOI : 10.1016/S0099-2399(06)81610-9

A. D. Walmsley, C. Murgel, and K. Krell, Canal markings produced by endosonic instruments, Dental Traumatology, vol.15, issue.2, pp.84-93, 1991.
DOI : 10.1111/j.1600-9657.1991.tb00190.x

T. M. Waltimo, M. Haapasalo, M. Zehnder, and J. Meyer, Clinical aspects related to endodontic yeast infections, Endodontic Topics, vol.30, issue.1, pp.66-78, 2004.
DOI : 10.1111/j.1365-2591.2004.00752.x

T. M. Waltimo, D. Orstavik, E. K. Siren, and M. Haapasalo, In vitro susceptibility of Candida albicans to four disinfectants and their combinations, International Endodontic Journal, vol.10, issue.6, pp.32-421, 1999.
DOI : 10.1111/j.1399-302X.1995.tb00163.x

R. Walton and M. Torabinejad, Principles and practice of endodontics, pp.385-97, 1989.

R. N. Weller, J. M. Brady, and W. Bernier, Efficacy of ultrasonic cleaning, Journal of Endodontics, vol.6, issue.9, pp.740-743, 1980.
DOI : 10.1016/S0099-2399(80)80185-3

R. R. White, G. Hays, and L. Janer, Residual antimicrobial activity after canal irrigation with chlorhexidine, Journal of Endodontics, vol.23, issue.4, pp.23-229, 1997.
DOI : 10.1016/S0099-2399(97)80052-0

U. Wikesjo, A biochemical approach to periodontal regeneration: Tetracycline treatment conditions dentin surfaces, Journal of Periodontal Research, vol.17, issue.4, pp.322-331, 1986.
DOI : 10.1902/jop.1981.52.10.613

M. K. Wu, P. Dummer, and P. Wesselink, Consequences of and strategies to deal with residual post-treatment root canal infection, International Endodontic Journal, vol.26, issue.21, pp.39-343, 2006.
DOI : 10.1016/0030-4220(82)90196-7

R. S. Yamada, A. Armas, M. Goldman, and P. Lin, A scanning electron microscopic comparison of a high volume final flush with several irrigating solutions: Part 3, Journal of Endodontics, vol.9, issue.4, pp.137-179, 1983.
DOI : 10.1016/S0099-2399(83)80032-6

M. Yamaguchi, K. Yoshida, R. Suzuki, and H. Nakamura, Root canal irrigation with citric acid solution, Journal of Endodontics, vol.22, issue.1, pp.22-27, 1996.
DOI : 10.1016/S0099-2399(96)80232-9

S. Henry, H. Vannesson, V. Stebut, and J. , High precision, simulated cutting efficiency measurement of endodontic root canal instruments: influence of file configuration and lubrication, J. Endod, vol.9, pp.16-418, 1990.

G. , P. P. Messer, and H. , The principles of techniques for cleaning root canals, Aust. Dent. J, vol.1, pp.52-52, 2007.

A. Zamany, K. Safavi, and L. Spangberg, The effect of chlorhexidine as an endodontic disinfectant. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.5, pp.96-578, 2003.

M. Zehnder, M. Grawehr, G. Hasselgren, and T. Waltimo, Tissue-dissolution capacity and dentin-disinfecting potential of calcium hydroxide mixed with irrigating solutions. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.5, pp.96-608, 2003.

M. Zehnder, D. Kosicki, H. Luder, B. Sener, and T. Waltimo, Tissue-dissolving capacity and antibacterial effect of buffered and unbuffered hypochlorite solutions. Oral Surg, Oral Med. Oral Pathol. Oral Radiol. Endod, vol.6, pp.94-756, 2002.

M. Zehnder, P. Schmidlin, B. Sener, and T. Waltimo, Chelation in Root Canal Therapy Reconsidered, Journal of Endodontics, vol.31, issue.11, pp.31-817, 2005.
DOI : 10.1097/01.don.0000158233.59316.fe