A. Baird, K. Lovblad, G. Schlaug, R. Edelman, and S. Warach, Multiple acute stroke syndrome: Marker of embolic disease?, Neurology, vol.54, issue.3, pp.674-678, 2000.
DOI : 10.1212/WNL.54.3.674

J. Roh, D. Kang, S. Lee, B. Yoon, and K. Chang, Significance of Acute Multiple Brain Infarction on Diffusion-Weighted Imaging, Stroke, vol.31, issue.3, pp.688-694, 2000.
DOI : 10.1161/01.STR.31.3.688

H. Wen, W. Lam, and T. Rainer, Multiple acute cerebral infarcts on diffusion-weighted imaging and risk of recurrent stroke, Neurology, vol.63, issue.7, pp.1317-1319, 2004.
DOI : 10.1212/01.WNL.0000140490.22251.B6

A. Cho, J. Kim, S. Jeon, S. Kwon, D. Lee et al., Mechanism of multiple infarcts in multiple cerebral circulations on diffusion-weighted imaging, Journal of Neurology, vol.63, issue.7, pp.924-930, 2007.
DOI : 10.1212/01.WNL.0000140490.22251.B6

D. Kang, L. Latour, J. Chalela, J. Dambrosia, and S. Warach, Early and late recurrence of ischemic lesion on MRI: Evidence for a prolonged stroke-prone state?, Neurology, vol.63, issue.12, pp.2261-2265, 2004.
DOI : 10.1212/01.WNL.0000147295.50029.67

S. Siemonsen, K. Mouridsen, and B. Holst, Quantitative T2 Values Predict Time From Symptom Onset in Acute Stroke Patients, Stroke, vol.40, issue.5, pp.1612-1616, 2009.
DOI : 10.1161/STROKEAHA.108.542548

G. Thomalla, P. Rossbach, and M. Rosenkranz, Negative fluid-attenuated inversion recovery imaging identifies acute ischemic stroke at 3 hours or less, Annals of Neurology, vol.29, issue.6, pp.724-732, 2009.
DOI : 10.1038/jcbfm.1985.34

M. Petkova, R. S. Lamy, and C. , MRI predicts time from symptom onset in acute stroke patients: implications for patients with unknown onset time, Radiology, 2010.

P. Sylaja, S. Coutts, S. Subramaniam, M. Hill, M. Eliasziw et al., Acute ischemic lesions of varying ages predict risk of ischemic events in stroke/TIA patients, Neurology, vol.68, issue.6, pp.415-419, 2007.
DOI : 10.1212/01.wnl.0000252938.76188.52

J. Roquer, A. Rodriguez-campello, and E. Cuadrado-godia, Acute brain MRI???DWI patterns and stroke recurrence after mild-moderate stroke, Journal of Neurology, vol.63, issue.6, pp.947-953, 2010.
DOI : 10.1212/01.WNL.0000140490.22251.B6

J. Gurwitz, J. Gore, and R. Goldberg, Risk for Intracranial Hemorrhage after Tissue Plasminogen Activator Treatment for Acute Myocardial Infarction, Annals of Internal Medicine, vol.129, issue.8, pp.597-604, 1998.
DOI : 10.7326/0003-4819-129-8-199810150-00002

H. Adams, R. Adams, D. Zoppo, G. Goldstein, and L. , Guidelines for the Early Management of Patients With Ischemic Stroke: 2005 Guidelines Update A Scientific Statement From the Stroke Council of the American Heart Association/American Stroke Association, Stroke, vol.36, issue.4, pp.916-923, 2005.
DOI : 10.1161/01.STR.0000163257.66207.2d

J. Norris, A. Buchan, and R. Cote, Conclusions:, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, vol.27, issue.03
DOI : 10.1056/NEJM199512143332401

. Actilyse, Available at: http://emc.medicines.org.uk/emc, p.308

J. Fiehler, G. Albers, and J. Boulanger, Bleeding Risk Analysis in Stroke Imaging Before ThromboLysis (BRASIL): Pooled Analysis of T2*-Weighted Magnetic Resonance Imaging Data From 570 Patients, Stroke, vol.38, issue.10, pp.2738-2744, 2007.
DOI : 10.1161/STROKEAHA.106.480848

W. Kakuda, V. Thijs, and M. Lansberg, Clinical importance of microbleeds in patients receiving IV thrombolysis, Neurology, vol.65, issue.8, pp.1175-1178, 2005.
DOI : 10.1212/01.wnl.0000180519.27680.0f

W. Hacke, M. Kaste, and E. Bluhmki, Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke, New England Journal of Medicine, vol.359, issue.13, pp.1317-1329, 2008.
DOI : 10.1056/NEJMoa0804656

H. Adams, J. Bendixen, B. Kappelle, and L. , Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment, Stroke, vol.24, issue.1, pp.35-41, 1993.
DOI : 10.1161/01.STR.24.1.35

W. Hacke, M. Kaste, and C. Fieschi, Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS), JAMA: The Journal of the American Medical Association, vol.274, issue.13, pp.1017-1025, 1995.
DOI : 10.1001/jama.274.13.1017

N. Wahlgren, N. Ahmed, and A. Davalos, Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study, The Lancet, vol.369, issue.9558, pp.275-282, 2007.
DOI : 10.1016/S0140-6736(07)60149-4

W. Hacke, M. Kaste, and C. Fieschi, Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II), The Lancet, vol.352, issue.9136, pp.1245-1251, 1998.
DOI : 10.1016/S0140-6736(98)08020-9

B. Campbell, S. Christensen, and K. Butcher, Regional Very Low Cerebral Blood Volume Predicts Hemorrhagic Transformation Better Than Diffusion-Weighted Imaging Volume and Thresholded Apparent Diffusion Coefficient in Acute Ischemic Stroke, Stroke, vol.41, issue.1, pp.82-88, 2010.
DOI : 10.1161/STROKEAHA.109.562116

J. Fiehler, S. Siemonsen, G. Thomalla, T. Illies, and T. Kucinski, Combination of T2*W and FLAIR Abnormalities for the Prediction of Parenchymal Hematoma Following Thrombolytic Therapy in 100 Stroke Patients, Journal of Neuroimaging, vol.105, issue.suppl 2, pp.311-316, 2009.
DOI : 10.1007/978-3-7091-6467-9_4

T. Neumann-haefelin, S. Hoelig, and J. Berkefeld, Leukoaraiosis Is a Risk Factor for Symptomatic Intracerebral Hemorrhage After Thrombolysis for Acute Stroke, Stroke, vol.37, issue.10, pp.2463-2466, 2006.
DOI : 10.1161/01.STR.0000239321.53203.ea

M. Lansberg, V. Thijs, and R. Bammer, Risk Factors of Symptomatic Intracerebral Hemorrhage After tPA Therapy for Acute Stroke, Stroke, vol.38, issue.8, pp.2275-2278, 2007.
DOI : 10.1161/STROKEAHA.106.480475

A. Cho, J. Kim, and S. Kim, Focal Fluid-Attenuated Inversion Recovery Hyperintensity Within Acute Diffusion-Weighted Imaging Lesions Is Associated With Symptomatic Intracerebral Hemorrhage After Thrombolysis, Stroke, vol.39, issue.12, pp.3424-3426, 2008.
DOI : 10.1161/STROKEAHA.108.516740

G. Graham, Tissue Plasminogen Activator for Acute Ischemic Stroke in Clinical Practice: A Meta-Analysis of Safety Data, Stroke, vol.34, issue.12, pp.2847-2850, 2003.
DOI : 10.1161/01.STR.0000101752.23813.C3

W. Hacke, G. Donnan, and C. Fieschi, Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials, Lancet, vol.363, pp.768-774, 2004.

C. Kidwell, J. Chalela, and J. Saver, Comparison of MRI and CT for detection of acute intracerebral hemorrhage Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study Group, JAMA Stroke, vol.29228, issue.33, pp.1823-18302109, 1997.

M. Hill, P. Barber, A. Demchuk, R. Sevick, R. Frayne et al., Symptomatic hemorrhage after alteplase therapy not due to silent ischemia, BMC Neurology, vol.29, issue.9, p.1, 2001.
DOI : 10.1161/01.STR.29.8.1504

K. Lees, E. Bluhmki, V. Kummer, and R. , Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials, The Lancet, vol.375, issue.9727, pp.1695-1703, 2010.
DOI : 10.1016/S0140-6736(10)60491-6