, , p.11
, , p.11
, , p.12
, , p.12
, , p.13
, , p.13
, , p.13
, , p.14
, , p.14
, , p.14
, , p.16
Mise au point d'un protocole d'hybridation d'une sonde sur cellules bactériennes, p.17 ,
18 A. Validation des méthodes d'analyses ,
,
,
, , p.20
,
, , p.22
, , p.23
, , p.24
, , p.25
, , p.25
, , p.25
, , p.26
, , p.27
, , p.28
, , p.29
, , p.30
, , p.31
, , p.33
, , p.35
, , p.40
, 49 humain .Gastroentérologie Clinique et Biologique, pp.17-23
Peptococcus magnus: A Significant Human Pathogen, Annals of Internal Medicine, vol.93, issue.2, pp.244-248, 1980. ,
DOI : 10.7326/0003-4819-93-2-244
Probiotiques et??cancer colorectal, Nutrition Clinique et M??tabolisme, vol.21, issue.2, pp.85-88, 2007. ,
DOI : 10.1016/j.nupar.2007.04.001
Further Studies on New Milk-Free Media for the Standard Plate Count of Dairy Products, American Journal of Public Health and the Nations Health, vol.43, issue.7, pp.869-872, 1953. ,
DOI : 10.2105/AJPH.43.7.869
L'utilisation des pesticides en France état des lieux et perspectives de réduction, NESE, issue.35, pp.7-26, 2011. ,
, Mise en place de la flore intestinale du nouveau-né, 2007.
, Gastroentérologie Clinique et Biologique, vol.31, issue.5, pp.533-542
The Significance of Sodium Chloride in Studies of Staphylococci1, Journal of Bacteriology, vol.50, issue.2, pp.201-203, 1945. ,
Prébiotiques et fonctions gastro-intestinales :revue des effets et des perspectives, Cah. Nutr. Diét, issue.38, p.6, 2003. ,
Microbiote intestinal et obésité, Objectif nutrition, issue.89, p.13, 2008. ,
Probiotiques : Adaptation à l'environnement digestif, Cahiers de nutrition et de diététique, pp.355-362, 2013. ,
Une ??re nouvelle dans le domaine des interactions entre le microbiote et la sant?? humaine, Gastroent??rologie Clinique et Biologique, vol.34, issue.4, pp.1-6, 2010. ,
DOI : 10.1016/S0399-8320(10)70001-4
Flore intestinale et??sant??: quels??enjeux?, Nutrition Clinique et M??tabolisme, vol.21, issue.2, pp.76-80, 2007. ,
DOI : 10.1016/j.nupar.2007.04.003
Development of a Six Stage Culture System for Simulating the Gastrointestinal Microbiota of Weaned Infants, Microbial Ecology in Health and Disease, vol.13, issue.2, 2001. ,
A medium for the cultivation of lactobacille, J, 1960. ,
, Bacteriol, vol.23, pp.130-135
Prebiotic effects of chicory inulin in the simulator of the human intestinal microbial ecosystem, FEMS Microbiology Ecology, vol.29, issue.1, pp.143-153, 2004. ,
DOI : 10.1093/nar/29.1.181
Le dosage de l'inuline : mise au point, Annales de Biologie Clinique, vol.69, issue.3, pp.273-284, 2011. ,
Characterisation of Eubacterium-like strains isolated from oral infections, Journal of Medical Microbiology, vol.50, issue.11, pp.947-951, 2001. ,
DOI : 10.1099/0022-1317-50-11-947
, 21
Human colonic microbiota associated with diet, obesity and weight loss, International Journal of Obesity, vol.87, issue.11, pp.1720-1724, 2008. ,
DOI : 10.1016/j.diagmicrobio.2004.08.012
Probiotics and prebiotics and health in ageing populations, Maturitas, vol.75, issue.1, pp.44-50, 2013. ,
DOI : 10.1016/j.maturitas.2013.02.004
probiotiques et pr??biotiques, Journal de P??diatrie et de Pu??riculture, vol.14, issue.2, pp.77-81, 2001. ,
DOI : 10.1016/S0987-7983(01)80015-3
Interaction Between ABCB1 and Professional Exposure to Organochlorine Insecticides in Parkinson Disease, Archives of Neurology, vol.67, issue.6, pp.739-745, 2010. ,
DOI : 10.1001/archneurol.2010.101
Diversity of the Human Intestinal Microbial Flora, Diversity of the Human Intestinal Microbial Flora, pp.1635-1638, 2005. ,
DOI : 10.1126/science.1110591
Juvenile ferric iron prevents microbiota dysbiosis and colitis in adult rodents, World Journal of Gastroenterology, vol.18, issue.21, pp.2619-2629, 2012. ,
DOI : 10.3748/wjg.v18.i21.2619
Measurement of gastrointestinal pH profiles in normal ambulant human subjects., Gut, vol.29, issue.8, pp.1035-1041, 1988. ,
DOI : 10.1136/gut.29.8.1035
Fate and effects of Camembert cheese micro-organisms in the human colonic microbiota of healthy volunteers after regular Camembert consumption, International Journal of Food Microbiology, vol.125, issue.2, pp.176-181, 2008. ,
DOI : 10.1016/j.ijfoodmicro.2008.03.044
The ecology, epidemiology and virulence of Enterococcus, Microbiology, vol.12, issue.4, pp.1749-1757, 2009. ,
DOI : 10.1016/j.cbpa.2008.06.015
2013. Pesticides, depression and suicide: A systematic review of the epidemiological evidence, International journal of hygiene and environmental health ,
Comparative assessment of human and farm animal faecal microbiota using real-time quantitative PCR, FEMS Microbiology Ecology, vol.4, issue.3, pp.351-362, 2009. ,
DOI : 10.1111/j.1348-0421.2002.tb02709.x
Species Specific Identification of Nine Human Bifidobacterium spp. in Feces, Systematic and Applied Microbiology, vol.25, issue.4, pp.536-543, 2002. ,
DOI : 10.1078/07232020260517670
Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics, The Journal of Nutrition, vol.125, issue.6, pp.1401-1412, 1995. ,
Pesticides and Health Risks, Journal of Obstetric, Gynecologic & Neonatal Nursing, vol.39, issue.1, pp.103-110, 2010. ,
DOI : 10.1111/j.1552-6909.2009.01092.x
Functionality of enterococci in dairy products, International Journal of Food Microbiology, vol.88, issue.2-3, pp.2-3, 2003. ,
DOI : 10.1016/S0168-1605(03)00183-1
La flore intestinale??: un monde vivant ?? pr??server, Journal de P??diatrie et de Pu??riculture, vol.22, issue.3, pp.102-106, 2009. ,
DOI : 10.1016/j.jpp.2009.03.007
11 -Le système digestif, Mémo-guide infirmier, pp.80-89, 2010. ,
Laboratory Studies with a Selective Enterococcus 40, 1970. ,
Impact of chronic exposure to low doses of chlorpyrifos on the intestinal microbiota in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®) and in the rat . Environmental science and pollution research international, 2012. ,
Clostridium Difficile Infection in Older Adults: A Review and Update on Its Management, The American Journal of Geriatric Pharmacotherapy, vol.10, issue.1, pp.14-24, 2012. ,
DOI : 10.1016/j.amjopharm.2011.12.004
Probiotic and Gut Lactobacilli and Bifidobacteria: Molecular Approaches to Study Diversity and Activity, Annual Review of Microbiology, vol.63, issue.1, pp.269-290, 2009. ,
DOI : 10.1146/annurev.micro.091208.073341
Intestinal Enterobacteriaceae and Escherichia coli populations in Japanese adults demonstrated by the reverse transcription-quantitative PCR and the clone library analyses, Journal of Microbiological Methods, vol.92, issue.2, pp.213-219, 2013. ,
DOI : 10.1016/j.mimet.2012.12.008
La constipation, Actualit??s Pharmaceutiques, vol.47, issue.477, pp.34-35, 2008. ,
DOI : 10.1016/S0515-3700(08)70134-4
Microflore de la m??re et du nouveau-n????: quelques aspects p??rinataux, Journal de P??diatrie et de Pu??riculture, vol.21, issue.8, pp.339-343, 2008. ,
DOI : 10.1016/j.jpp.2008.09.006
Human gut microbes associated with obesity, Nature, vol.308, issue.7122, pp.1022-1023, 2006. ,
DOI : 10.1126/science.1110591
,
Rapid Identification of the Species of the Bacteroides Fragilis Group by Multiplex PCR Assays Using Group-and Species-specific Primers, FEMS Microbiology Letters, vol.222, issue.1, pp.9-16, 2003. ,
Reclassification of Clostridium coccoides, Ruminococcus hansenii, Ruminococcus hydrogenotrophicus, Ruminococcus luti, Ruminococcus productus and Ruminococcus schinkii as Blautia coccoides gen. nov., comb. nov., Blautia hansenii comb. nov., Blautia hydrogenotrophica comb. nov., Blautia luti comb. nov., Blautia producta comb. nov., Blautia schinkii comb. nov. and description of Blautia wexlerae sp. nov., isolated from human faeces, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol.64, issue.10, pp.1896-1902, 2008. ,
DOI : 10.1128/AEM.68.9.4225-4232.2002
Effects of ageing on gastrointestinal motor function, Age and Ageing, vol.33, issue.2, 2004. ,
DOI : 10.1093/ageing/afh040
, Age Ageing, issue.33, pp.154-159
Avant sa naissance, un b??b?? d??j?? immunocomp??tent, Revue Francophone des Laboratoires, vol.2011, issue.431, 2011. ,
DOI : 10.1016/S1773-035X(11)70883-8
, Revue Francophone des Laboratoires, issue.431, p.24
The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age, BMC Microbiology, vol.9, issue.1, p.123, 2009. ,
DOI : 10.1186/1471-2180-9-123
URL : https://hal.archives-ouvertes.fr/hal-00657910
Development of intestinal microbiota in infants and its impact on health, 596?599. 53 Matamoros, pp.167-173, 1969. ,
Development of a 5-step multi-chamber reactor as a simulation of the human intestinal microbial ecosystem, Applied Microbiology and Biotechnology, vol.39, issue.2, pp.254-258, 1993. ,
DOI : 10.1007/BF00228615
Human Fecal Flora: The Normal Flora of 20 Japanese-Hawaiians, 1974. ,
, Applied Microbiology, vol.27, issue.5, pp.961-979
Cin??tique d'??tablissement de la microflore digestive chez le nouveau-n?? humain en fonction de la nature du lait, Reproduction Nutrition D??veloppement, vol.26, issue.2B, pp.745-753, 1986. ,
DOI : 10.1051/rnd:19860429
Use of a modified MacConkey agar medium for the selective growth and enumeration of all Enterobacteriaceae, J. Bacteriol, vol.84, p.381, 1962. ,
Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives, Toxicology and Applied Pharmacology, vol.268, issue.2, 2013. ,
DOI : 10.1016/j.taap.2013.01.025
Nutriose, a prebiotic low-digestible carbohydrate, stimulates gut mucosal immunity and prevents TNBS-induced colitis in piglets, Inflammatory Bowel Diseases, vol.54, issue.5, pp.783-794, 2010. ,
DOI : 10.1590/S0043-31442005000300011
, , 2004.
, In vitro alterations of intestinal bacterial microbiota in fecal samples during storage, Diagnostic Microbiology and Infectious Disease, vol.50, issue.4, pp.237-245
Development of the Human Infant Intestinal Microbiota, PLoS Biology, vol.69, issue.7, 2007. ,
DOI : 10.1371/journal.pbio.0050177.sg002
A New Culture Medium for Medical Bacteriology, American Journal of Clinical Pathology, vol.45, issue.4, pp.502-504, 1966. ,
L'humanité face à l'effet de serre additionnel qu'elle crée .Comptes Rendus del'Académie des Sciences -Series IIA -Earth and Planetary Science, pp.775-786, 2001. ,
La PCR en temps réel: principes et applications, Reviews in Biology and Biotechnology, vol.2, issue.2, pp.2-11, 2002. ,
Bénéfices cliniques des prébiotiques sur l'infection et l'allergie . Archives de Pédiatrie 14, pp.8-10, 2007. ,
A new selective medium for the isolation of glucose non-fermenting bifidobacteria from hen caeca, Journal of Microbiological Methods, vol.43, issue.2, pp.127-132, 2000. ,
DOI : 10.1016/S0167-7012(00)00205-0
Investigating the Role of Small, Acid soluble Spore Proteins (SASPs) in the Resistance of Clostridium Perfringens Spores to Heat, BMC Microbiology, vol.6, issue.1, p.50, 2006. ,
DOI : 10.1186/1471-2180-6-50
Flore microbienne intestinale: physiologie et pathologie digestives, 2004. ,
Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii, British Journal of Nutrition, vol.44, issue.04, pp.541-550, 2009. ,
DOI : 10.1128/AEM.02340-06
The prebiotic properties of oligofructose at low intake levels, Nutrition Research, vol.21, issue.6, pp.843-848, 2001. ,
DOI : 10.1016/S0271-5317(01)00284-6
Sudden death syndrome in adult cows associated with Clostridium perfringens type E, Anaerobe, vol.20, pp.1-4, 2013. ,
DOI : 10.1016/j.anaerobe.2013.01.001
Influence de la consommation de laits fermentés au Lactobacillus casei (Danone strain 001) sur les diarrhées de l'enfant sain en crèche, Archives de Pediatrie, vol.3, issue.12, pp.1291-1291, 1997. ,
Chicory fructooligosaccharides and the gastrointestinal tract, Nutrition, vol.16, issue.7-8, pp.677-679, 2000. ,
DOI : 10.1016/S0899-9007(00)00244-6
Analyse de l'eau. Identification des coliformes et en particulier d' Escherichia coli, p.809, 1984. ,
Prébiotiques et minéraux : des espoirs et des inconnues, Health and food, issue.73, pp.10-11, 2005. ,
THE DEVELOPMENT OF THE BACTERIAL FLORA IN THE GASTROINTESTINAL TRACT OF MICE, Journal of Experimental Medicine, vol.122, issue.1, pp.59-66, 1965. ,
DOI : 10.1084/jem.122.1.59
Microbiote intestinal et MICI, Gastroent??rologie Clinique et Biologique, vol.34, issue.4, pp.48-55, 2010. ,
DOI : 10.1016/S0399-8320(10)70007-5
Microbiote et maladies inflammatoires chroniques intestinales, Revue du Rhumatisme, vol.78, pp.31-32, 2011. ,
DOI : 10.1016/S1169-8330(11)70043-6
I will survive: DNA protection in bacterial spores, Trends in Microbiology, vol.15, issue.4, p.80, 2007. ,
DOI : 10.1016/j.tim.2007.02.004
New Quantitative, Qualitative, and Confirmatory Media for Rapid Analysis of Food for Clostridium perfringens1, Applied Microbiology, vol.21, issue.3, pp.500-506, 1971. ,
Numbers of enterococci in water, sewage, and feces determined by the membrane filter technique with an improved medium1, Journal of Bacteriology, vol.74, issue.5, pp.591-595, 1957. ,
Nonlinear partial differential equations and applications: Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells, Proceedings of the National Academy of Sciences, vol.22, issue.2, pp.15451-15455, 2002. ,
DOI : 10.1006/prep.2001.1434
URL : http://www.pnas.org/content/99/24/15451.full.pdf
The Microbial Ecology of the Large Bowel of Breastfed and Formula-fed Infants During the First Year of Life, Journal of Medical Microbiology, vol.15, issue.2, pp.189-203, 1982. ,
DOI : 10.1099/00222615-15-2-189
, Santé et environnement . Comptes Rendus de l'Académie des Sciences ? Serie III Sciences de la Vie, pp.651-664, 2000.
The intestinal microbiota in the rat model: major breakthroughs from new technologies . Animal health research reviews, Animal Diseases, vol.13, issue.1, pp.54-63, 2012. ,
Microbial Community Development in a Dynamic Gut Model Is Reproducible, Colon Region Specific, and Selective for Bacteroidetes and Clostridium Cluster IX, Consommation de pesticides phytosanitaires, pp.5237-5246, 2010. ,
DOI : 10.1128/AEM.00759-10
URL : https://hal.archives-ouvertes.fr/hal-01607673
, In Vitro Synthesis of Fractofuranosyl-only Oligosaccharides from Inulin and Fructose by Purified Chicory Root Fructan:fructan Fructosyl Transferase, Physiologia Plantarum, vol.97, issue.2, pp.346-352, 1996.
The Effect of Selected Synbiotics on Microbial Composition and Short-Chain Fatty Acid Production in a Model System of the Human Colon, PLoS ONE, vol.7, issue.10, p.47212, 2012. ,
DOI : 10.1371/journal.pone.0047212.s003
Pesticide residues in market foods in Shaanxi Province of China in 2010, Food Chemistry, vol.138, issue.2-3, pp.2016-2025, 2013. ,
DOI : 10.1016/j.foodchem.2012.11.116
In utero pesticide exposure and childhood morbidity, Environmental Research, vol.103, issue.1, pp.79-86, 2007. ,
DOI : 10.1016/j.envres.2006.09.001
The gastrointestinal tract and its indigenous microbiota, Microbial Inhabitants of Humans, 2004. ,
DOI : 10.1017/CBO9780511735080.008
, , 2009.
, Evolution de la flore fécale au cours de la vie Graphique 2 : Mélange 50/50 (E.coli/E.coli traité à l'éthanol 70%) marqué au syto 9 + iodure de propidium, Figure, vol.5, pp.10-13
, Graphique 3 : Culture pure Escherichia coli marqué au syto 9 + iodure de propidium, pp.10-13
, Graphique 4 : Escherichia coli traité à l'éthanol 70%marqué au syto 9 + iodure de propidium, pp.10-13
, Graphique 7 : Etude du microbiote intestinal par microbiologie classique en fonction de l'âge
, Etude du microbiote intestinal par qPCR en fonction de l'âge 10, Graphique, vol.8, issue.30, pp.50-70
, femme adulte inuline 2 mois femme adulte inuline 1 mois adulte femme congelé 1 jour Ratio Firmicutes
, Ratio Firmicutes /Bacteroidetes en fonction d'un traitement inuline, Graphique, vol.15
, Etude de la flore totale du microbiote intestinal par cytométrie de flux dans l'étude in vivo, Graphique, vol.19
, Etude in vitro de la flore totale aérobie dans chaque compartiment du Vitrosim, Graphique, vol.20
, Etude in vitro de la flore totale anaérobie facultative dans chaque compartiment, Graphique, vol.21
, Evolution des genres Streptococcus spp/Enterococcus spp dans le Vitrosim en fonction du temps de traitement à l'inuline, Graphique, vol.23
, Evolution des Enterobacteriaceae dans le Vitrosim en fonction du temps de traitement à l'inuline, Graphique, vol.24
, Evolution des profils bactériens au sein du Vitrosim (Fermenteur 6) en fonction du temps de traitement à l'inuline, Graphique, vol.25