R. Guaita, M. Pichiule, T. Maté, C. Linares, and J. Díaz, Short-term impact of particulate matter (PM(2.5)) on respiratory mortality in Madrid, Int J Environ Health Res, vol.21, pp.260-274, 2011.

F. J. Kelly and J. C. Fussell, Air pollution and airway disease, Clin. Exp. Allergy, vol.41, pp.1059-1071, 2011.
DOI : 10.1111/j.1365-2222.2011.03776.x

K. Katanoda, An association between long-term exposure to ambient air pollution and mortality from lung cancer and respiratory diseases in Japan, J Epidemiol, vol.21, pp.132-143, 2011.
DOI : 10.2188/jea.je20100098

URL : https://www.jstage.jst.go.jp/article/jea/21/2/21_JE20100098/_pdf

L. Modig, K. Torén, C. Janson, B. Jarvholm, and B. Forsberg, Vehicle exhaust outside the home and onset of asthma among adults, Eur. Respir. J, vol.33, pp.1261-1267, 2009.
DOI : 10.1183/09031936.00101108

URL : http://erj.ersjournals.com/content/33/6/1261.full.pdf

L. Carbajal-arroyo, Impact of traffic flow on the asthma prevalence among school children in Lima, Peru, J Asthma, vol.44, pp.197-202, 2007.

S. H. Ling and S. F. Van-eeden, Particulate matter air pollution exposure: role in the development and exacerbation of chronic obstructive pulmonary disease, Int J Chron Obstruct Pulmon Dis, vol.4, pp.233-243, 2009.

C. L. Robinson, Effect of urbanisation on asthma, allergy and airways inflammation in a developing country setting, Thorax, 2011.

J. Øvrevik, M. Låg, J. A. Holme, P. E. Schwarze, and M. Refsnes, Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution, Toxicology, vol.259, pp.46-53, 2009.

L. Risom, P. Møller, and S. Loft, Oxidative stress-induced DNA damage by particulate air pollution, Mutat. Res, vol.592, pp.119-137, 2005.
DOI : 10.1016/j.mrfmmm.2005.06.012

P. E. Schwarze, Particulate matter properties and health effects: consistency of epidemiological and toxicological studies, Hum Exp Toxicol, vol.25, pp.559-579, 2006.
DOI : 10.1177/096032706072520

A. E. Aust, Particle characteristics responsible for effects on human lung epithelial cells. Res Rep Health Eff Inst 1-65; discussion, pp.67-76, 2002.

C. Monn and S. Becker, Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine (PM2.5) and coarse particles (PM10-2.5) in outdoor and indoor air, Toxicol. Appl. Pharmacol, vol.155, pp.245-252, 1999.
DOI : 10.1006/taap.1998.8591

K. Donaldson and V. Stone, Current hypotheses on the mechanisms of toxicity of ultrafine particles, Ann. Ist. Super. Sanita, vol.39, pp.405-410, 2003.

W. Macnee and K. Donaldson, Mechanism of lung injury caused by PM10 and ultrafine particles with special reference to COPD, Eur Respir J Suppl, vol.40, pp.47-51, 2003.

P. Mantecca, Comparative acute lung inflammation induced by atmospheric PM and sizefractionated tire particles, Toxicol. Lett, vol.198, pp.244-254, 2010.
DOI : 10.1016/j.toxlet.2010.07.002

M. Gualtieri, Differences in cytotoxicity versus pro-inflammatory potency of different PM fractions in human epithelial lung cells, Toxicol In Vitro, vol.24, pp.29-39, 2010.

E. Samoli, P. T. Nastos, A. G. Paliatsos, K. Katsouyanni, and K. N. Priftis, Acute effects of air pollution on pediatric asthma exacerbation: evidence of association and effect modification, Environ. Res, vol.111, pp.418-424, 2011.

J. Grigg, Air pollution and children's respiratory health-gaps in the global evidence, Clin. Exp. Allergy, vol.41, pp.1072-1075, 2011.
DOI : 10.1111/j.1365-2222.2011.03790.x

F. Tramuto, Urban air pollution and emergency room admissions for respiratory symptoms: a case-crossover study in Palermo, Italy. Environ Health, vol.10, pp.31-31

S. S. Hecht, Tobacco smoke carcinogens and lung cancer, J. Natl. Cancer Inst, vol.91, pp.1194-1210, 1999.
DOI : 10.1007/978-1-61737-995-6_3

S. Teramoto, T. Ishii, H. Yamamoto, Y. Yamaguchi, and T. Matsuse, Xenobiotic enzymes and genetics of COPD, Chest, vol.127, pp.408-409, 2005.

J. Y. Zhang, Y. Wang, and C. Prakash, Xenobiotic-metabolizing enzymes in human lung, Curr. Drug Metab, vol.7, pp.939-948, 2006.

N. Wong, L. S. Aung, H. H. Lamé, M. W. Wegesser, T. C. Wilson et al., Fine particulate matter from urban ambient and wildfire sources from California's San Joaquin Valley initiate differential inflammatory, oxidative stress, and xenobiotic responses in human bronchial epithelial cells, Toxicol In Vitro, 2011.

C. R. Rhoden, E. Ghelfi, and B. González-flecha, Pulmonary inflammation by ambient air particles is mediated by superoxide anion, Inhal Toxicol, vol.20, pp.11-15, 2008.

P. H. Danielsen, Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines, Chem. Res. Toxicol, vol.24, pp.168-184, 2011.

C. Kiyohara and K. Yoshimasu, Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis, Int J Med Sci, vol.4, pp.59-71, 2007.

M. Mehta, L. Chen, T. Gordon, W. Rom, and M. Tang, Particulate matter inhibits DNA repair and enhances mutagenesis, Mutat. Res, vol.657, pp.116-121, 2008.

D. K. Male, Y. Roitt, and . Immunologie, , 2007.

J. Nicolas and F. Bérard, Immunologie clinique et allergologie: compte rendu du séminaire 2003, Faculté de médecine, 2003.

T. L. Watterson, J. Sorensen, R. Martin, and R. A. Coulombe, Jr Effects of PM2.5 collected from Cache Valley Utah on genes associated with the inflammatory response in human lung cells, J. Toxicol. Environ. Health Part A, vol.70, pp.1731-1744, 2007.

A. B. Goulter, D. W. Harmer, and K. L. Clark, Evaluation of low density array technology for quantitative parallel measurement of multiple genes in human tissue, BMC Genomics, vol.7, p.34, 2006.

T. Langmann, Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues, Clin. Chem, vol.49, pp.230-238, 2003.

L. V. Abruzzo, Validation of oligonucleotide microarray data using microfluidic lowdensity arrays: a new statistical method to normalize real-time RT-PCR data, BioTechniques, vol.38, pp.785-792, 2005.

M. Erreni, Expression of chemokines and chemokine receptors in human colon cancer, Meth. Enzymol, vol.460, pp.105-121, 2009.

J. Leclerc, Xenobiotic metabolism and disposition in human lung: transcript profiling in non-tumoral and tumoral tissues, Biochimie, vol.93, pp.1012-1027, 2011.

A. I. Totlandsdal, F. R. Cassee, P. Schwarze, M. Refsnes, and M. Låg, Diesel exhaust particles induce CYP1A1 and pro-inflammatory responses via differential pathways in human bronchial epithelial cells, Part Fibre Toxicol, vol.7, p.41, 2010.

K. Dreij, K. Rhrissorrakrai, K. C. Gunsalus, N. E. Geacintov, and D. A. Scicchitano,

, diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway, Carcinogenesis, vol.31, pp.1149-1157, 2010.

T. E. Gram, Chemically reactive intermediates and pulmonary xenobiotic toxicity, Pharmacol. Rev, vol.49, pp.297-341, 1997.

A. Perret and D. Pompon, Electron shuttle between membrane-bound cytochrome P450 3A4 and b5 rules uncoupling mechanisms, Biochemistry, vol.37, pp.11412-11424, 1998.

D. Cao, P. A. Bromberg, and J. M. Samet, COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1, Am. J. Respir. Cell Mol. Biol, vol.37, pp.232-239, 2007.

H. Glatt, K. Rost, H. Frank, A. Seidel, and R. Kollock, Detoxification of promutagenic aldehydes derived from methylpyrenes by human aldehyde dehydrogenases ALDH2 and ALDH3A1, Arch. Biochem. Biophys, vol.477, pp.196-205, 2008.

N. Podechard, Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation, Toxicol. Lett, vol.177, pp.130-137, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00673238

S. A. Kraemer, K. A. Arthur, M. S. Denison, W. L. Smith, and D. L. Dewitt, Regulation of prostaglandin endoperoxide H synthase-2 expression by 2,3,7,8,-tetrachlorodibenzo-p-dioxin, Arch. Biochem. Biophys, vol.330, pp.319-328, 1996.

A. Puga, C. Ma, and J. L. Marlowe, The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways, Biochem. Pharmacol, vol.77, pp.713-722, 2009.

Z. Abdel-razzak, Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture, Mol. Pharmacol, vol.44, pp.707-715, 1993.

Y. Morel and R. Barouki, Down-regulation of cytochrome P450 1A1 gene promoter by oxidative stress. Critical contribution of nuclear factor 1, J. Biol. Chem, vol.273, pp.26969-26976, 1998.

A. E. Aitken and E. T. Morgan, Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes, Drug Metab. Dispos, vol.35, pp.1687-1693, 2007.

D. He, A. R. Frost, and C. N. Falany, Identification and immunohistochemical localization of Sulfotransferase 2B1b (SULT2B1b) in human lung, Biochim. Biophys. Acta, vol.1724, pp.119-126, 2005.

A. E. Aitken, T. A. Richardson, and E. T. Morgan, Regulation of drug-metabolizing enzymes and transporters in inflammation, Annu. Rev. Pharmacol. Toxicol, vol.46, pp.123-149, 2006.

M. L. Scapellato and M. Lotti, Short-term effects of particulate matter: an inflammatory mechanism?, Crit. Rev. Toxicol, vol.37, pp.461-487, 2007.

M. Pedroza, Interleukin-6 contributes to inflammation and remodeling in a model of adenosine mediated lung injury, PLoS ONE, vol.6, p.22667, 2011.

R. V. House and J. Descotes, Cytokines in human health: immunotoxicology, pathology, and therapeutic applications, 2007.

Z. Dagher, Pro-inflammatory effects of Dunkerque city air pollution particulate matter 2.5 in human epithelial lung cells (L132) in culture, J Appl Toxicol, vol.25, pp.166-175, 2005.

M. Rumelhard, K. Ramgolam, R. Hamel, F. Marano, and A. Baeza-squiban, Expression and role of EGFR ligands induced in airway cells by PM2.5 and its components, Eur. Respir. J, vol.30, pp.1064-1073, 2007.

C. A. Dinarello, Blocking IL-1 in systemic inflammation, J. Exp. Med, vol.201, pp.1355-1359, 2005.

A. Sahoo, Stat6 and c-Jun mediate Th2 cell-specific IL-24 gene expression, J. Immunol, vol.186, pp.4098-4109, 2011.

M. I. Talmadge, E. King, &. M. Schwarz, and T. E. Jr, Interstitial Lung Disease, 2009.

L. Zhang, Vanadium stimulates human bronchial epithelial cells to produce heparinbinding epidermal growth factor-like growth factor: a mitogen for lung fibroblasts, Am. J. Respir. Cell Mol. Biol, vol.24, pp.123-131, 2001.

A. Churg, B. Gilks, and J. Dai, Induction of fibrogenic mediators by fine and ultrafine titanium dioxide in rat tracheal explants, Am. J. Physiol, vol.277, pp.975-982, 1999.

J. Y. Liu, Rapid activation of PDGF-A and-B expression at sites of lung injury in asbestos-exposed rats, Am. J. Respir. Cell Mol. Biol, vol.17, pp.129-140, 1997.

T. Gray, Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1beta in human bronchial epithelia, Am. J. Physiol. Lung Cell Mol. Physiol, vol.286, pp.320-330, 2004.

M. C. Rose and J. A. Voynow, Respiratory tract mucin genes and mucin glycoproteins in health and disease, Physiol. Rev, vol.86, pp.245-278, 2006.

H. J. Kim, The role of Nox4 in oxidative stress-induced MUC5AC overexpression in human airway epithelial cells, Am. J. Respir. Cell Mol. Biol, vol.39, pp.598-609, 2008.