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, Ce taux global est comparable à celui de l'étude prospective portant sur la cohorte OUTCOMEREA(14) et à ceux rapportés par la métaanalyse de Schneider et al

, L'absence de différence entre les deux techniques d'épuration extra rénale peut être due à un nombre insuffisant de patients évoluant vers une insuffisance rénale chronique terminale nécessitant une épuration extra rénale définitive, La différence observée entre les deux techniques n'était plus retrouvée en sortie d'hospitalisation et à 6 mois

, Cette définition, bien que non consensuelle, est celle choisie par la plupart des études observationnelles et des essais randomisés. Cependant, l'absence de nécessité d'une épuration extra rénale ne signifie pas forcément que la récupération de la fonction rénale est totale, Le critère utilisé pour définir la récupération de la fonction rénale était l'absence de dépendance à une technique d'épuration extra rénale

, Le principal argument physiopathologique expliquant la tendance observée à une meilleure récupération de la fonction rénale des patients bénéficiant d'une hémofiltration continue est la meilleure tolérance hémodynamique lors de l'utilisation de cette technique. Néanmoins, plusieurs essais contrôlés ont échoué à démontrer une meilleure stabilité hémodynamique d'une technique continue, vol.18, p.27

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DOI : 10.1093/ndt/gfm019

URL : https://academic.oup.com/ndt/article-pdf/22/suppl_2/ii22/6835787/gfm019.pdf