A. D. Adinoff, J. Jr, R. B. Dolen, J. South, and M. A. , Chronic granulomatous disease and Pneumocystis carinii pneumonia, Pediatrics, vol.69, issue.1, pp.133-134, 1982.

A. Ahlin and A. Fasth, Chronic granulomatous disease-conventional treatment vs. hematopoietic stem cell transplantation: an update, Current Opinion Hematology, vol.22, issue.1, pp.41-45, 2015.

D. Alberti, A. Borsellino, C. Locatelli, R. Nani, M. Cheli et al., Percutaneous transhepatic alcoholization: a new therapeutic strategy in children with chronic granulomatous disease and liver abscess, Pediatric Infectious Disease Journal, vol.21, issue.11, pp.1081-1083, 2002.
DOI : 10.1097/00006454-200211000-00025

H. Aliabadi, R. Gonzalez, and P. G. Quie, Urinary tract disorders in patients with chronic granulomatous disease, The New England Journal of Medicine, vol.321, issue.11, pp.706-708, 1989.
DOI : 10.1056/nejm198909143211102

D. R. Ambruso, C. Knall, A. N. Abell, J. Panepinto, A. Kurkchubasche et al., Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation, Proceedings of the National Academy of Sciences of the USA, vol.97, issue.9, pp.4654-4659, 2000.
DOI : 10.1073/pnas.080074897

URL : http://www.pnas.org/content/97/9/4654.full.pdf

M. E. Ament and H. D. Ochs, Gastrointestinal manifestations of chronic granulomatous disease, New England Journal of Medicine, vol.288, issue.8, pp.382-387, 1973.
DOI : 10.1056/nejm197302222880802

M. Anderson-cohen, S. M. Holland, D. B. Kuhns, T. A. Fleisher, L. Ding et al., Severe phenotype of chronic granulomatous disease presenting in a female with a de novo mutation in gp91-phox and a non familial, extremely skewed X chromosome inactivation, Clinical Immunology, vol.109, issue.3, pp.308-317, 2003.

A. Aouba, B. Terrier, J. B. Arlet, L. Aaron, F. Suarez et al., Treatment of profound anemia with erythropoietin and steroids in a patient with X-linked chronic granulomatous disease associated with MacLeod erythrocyte phenotype, American Journal of Hematology, vol.82, issue.8, pp.773-774, 2007.

J. P. Arbuthnott, D. C. Coleman, and J. S. De-azavedo, Staphylococcal toxins in human diseases, Journal of Applied Bacteriology Symposium, pp.101-107, 1990.
DOI : 10.1111/j.1365-2672.1990.tb01802.x

G. Ayliffe, A. Buckles, M. W. Casewell, B. D. Cookson, R. A. Cox et al., Revised guidelines for the control of meticillin-resistant Staphylococcus aureus infection in hospitals, Journal of Hospital Infection, vol.39, issue.4, pp.253-290, 1998.

P. H. Azimi, J. G. Bodenbender, R. L. Hintz, and S. B. Kontras, Chronic granulomatous disease in three female siblings, Journal of American Medical Associations, vol.206, issue.13, pp.2865-2870, 1968.
DOI : 10.1001/jama.206.13.2865

R. L. Baehner and D. G. Nathan, Leukocyte oxidase: defective activity in chronic granulomatous disease, Science, vol.155, issue.3764, pp.835-836, 1967.

R. L. Baehner, D. G. Nathan, and M. L. Karnovsky, Correction of metabolic deficiencies in the leukocytes of patients with chronic granulomatous disease, The Journal of Clinical Investigation, vol.49, issue.5, pp.865-870, 1970.

C. N. Barese, W. S. Goebel, and M. C. Dinauer, Gene therapy for chronic granulomatous disease, Expert Opinion on Biological Therapy, vol.4, issue.9, pp.1423-1434, 2004.

P. A. Barry-lane, C. Patterson, M. Van-der-merwe, Z. Hu, S. M. Holland et al., p47phox is required for atherosclerotic lesion progression in ApoE(?/?) mice, The Journal of Clinical Investigation, vol.108, issue.10, pp.1513-1522, 2001.

J. Beauté, N. Mahlaoui, Y. Dudoit, R. Micol, L. Mignot et al., The French PID study group. The French national registry of primary immunodéficiency diseases, vol.135, pp.264-272, 2010.

J. Beauté, G. Obenga, L. Mignot, L. Mahlaoui, N. Bougnoux et al., Epidemiology and outcome of invasive fungal diseases in patients with chronic granulomatous disease: a multicenter study in France, The Pediatric Infectious Disease Journal, vol.30, issue.1, pp.57-62, 2011.

J. S. Beckman, The physiological and pathological chemistry of nitric oxide, Nitric oxide, Lancaster L Jr, pp.1-82

K. Bedard and K. H. Krause, The NOX family of ROS-generating NADPH oxidases: physiology and pathology, Physiological Reviews, vol.87, issue.1, pp.245-313, 2007.

H. Berendes, R. A. Bridges, and A. Good, A fatal granulomatous of childhood: the clinical study of a new syndrome

, Minnesota Medicine, vol.40, issue.5, pp.309-312, 1957.

B. Bielski and D. E. Cabelli, Superoxide and hydroxyl radical chemistry in aqueous solution, Blackie Academic & Professional, pp.66-76, 1995.

H. Bjorgvinsdottir, C. Ding, N. Pech, M. A. Gifford, L. L. Li et al., Retroviral-mediated gene transfer of gp91phox into bone marrow cells rescues defect in host defense against Aspergillus fumigatus in murine Xlinked chronic granulomatous disease, Blood, vol.89, issue.1, pp.41-48, 1997.

A. Bolanowski, R. B. Mannon, S. M. Holland, H. L. Malech, J. Aschan et al., Successful renal transplantation in patients with chronic granulomatous disease, American Journal of Transplantation, vol.6, issue.3, pp.636-639, 2006.

F. Brandrup, C. Koch, M. Petri, M. Schiodt, and K. S. Johansen, Discoid lupus erythematosus-like lesions and stomatitis in female carriers of X-linked chronic granulomatous disease, British Journal of Dermatology, vol.104, issue.5, pp.495-505, 1981.

R. A. Bridges, H. Berendes, and R. A. Good, A fatal granulomatous disease of childhood: the clinical, pathological and laboratory features of a new syndrome, American Journal of Diseases of Children, vol.97, issue.4, pp.387-408, 1959.

M. A. Briones, C. D. Josephson, and C. D. Hillyer, Granulocyte transfusion: revisited, Current Hematology Reports, vol.2, issue.6, pp.522-527, 2003.

S. M. Brzica, A. A. Pineda, H. F. Taswell, and K. H. Rhodes, Chronic granulomatous disease and the Mcleod phenotype. Successful treatment of infection with granulocyte transfusions resulting in subsequent hemolytic transfusion reaction, Mayo Clinic Proceedings, vol.52, issue.3, pp.153-156, 1977.

J. Bustamante, G. Aksu, G. Vogt, L. De-beaucoudrey, F. Genel et al., BCG-osis and tuberculosis in a child with chronic granulomatous disease, Journal of Allergy and Clinical Immunology, vol.120, issue.1, pp.32-38, 2007.

A. N. Cain, I. C. Hanson, L. Forbes, F. O. Seeborg, L. M. Noroski et al., Long-term organ function in children following hematopoietic stem cell transplantation for chronic granulomatous disease, Biology of Blood and Marrow Transplantation, vol.22, issue.3, pp.239-240, 2016.

C. M. Cale, L. Morton, and D. Glodblatt, Cutaneous and other lupus-like symptoms in carriers of X-linked chronic granulomatous disease : incidence and autoimmune serology, Clinical and Experimental Immunology, vol.148, issue.1, pp.79-84, 2007.

N. A. Carlone, A. M. Cuffini, M. Ferrero, V. Tullio, and G. Avetta, Cellular uptake, and intracellular bactericidal activity of teicoplanin in human macrophages, Journal of Antimicrobial Chemotherapy, vol.23, issue.6, pp.849-859, 1989.

C. M. Casimir, H. N. Bu-ghanim, A. R. Rodaway, D. L. Bentley, P. Rowe et al., Autosomal recessive chronic granulomatous disease caused by deletion at a dinucleotide repeat, Proceedings of the National Academy of Sciences of the USA, vol.88, issue.7, pp.2753-2757, 1991.
DOI : 10.1073/pnas.88.7.2753

URL : http://www.pnas.org/content/88/7/2753.full.pdf

P. Cathebras, C. Sauron, F. Morel, and M. J. Stasia, An unusual case of sarcoidosis, Lancet, vol.358, issue.9278, p.294, 2001.

M. Cavazzana-calvo and A. Fischer, Gene therapy for combined immunodeficiency: are we there yet?, The Journal of Clinical Investigation, vol.117, issue.6, pp.1456-1465, 2007.
DOI : 10.1172/jci30953

URL : http://www.jci.org/articles/view/30953/files/pdf

, Centers for Disease Control

, Follow-up on toxic-shock syndrome, Morbidity and Mortality Weekly Report, vol.29, pp.441-445, 1980.

S. Chatzipanagiotou, K. Takou, and A. Perogamvros, Cutaneous purulent aspergillosis in a young man with chronic granulomatous disease, Mycoses, vol.41, issue.9, pp.379-382, 1998.

J. Chaumeil, L. Baccon, P. Wutz, A. Heard, and E. , A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced, Genes & Development, vol.20, issue.16, pp.2223-2237, 2006.

T. W. Chin, E. R. Stiehm, J. Falloon, and J. I. Gallin, Corticosteroids in treatment of obstructive lesions chronic granulomatous disease, Journal of Pediatrics, vol.111, issue.3, pp.349-352, 1987.

J. Chu, H. H. Song, K. A. Zarember, T. A. Mills, and J. I. Gallin, Persistence of the bacterial pathogen Granulibacter bethesdensis in chronic granulomatous disease monocytes and macrophages lacking a functional NADPH oxidase, The Journal of Immunology, vol.191, issue.6, pp.3297-3307, 2013.

M. J. Chusid, J. A. Gelfand, C. Nutter, and A. S. Fauci, Letter: Pulmonary aspergillosis, inhalation of contaminated marijuana smoke, chronic granulomatous disease, Annals of Internal Medicine, vol.82, issue.5, pp.682-683, 1975.

M. J. Chusid, J. E. Parillo, and A. S. Fauci, Diagnosis in a 27-year-old man with Mycobacterium fortuitum, Journal of the American Medical Association, vol.233, issue.12, pp.1295-1296, 1975.

R. A. Clark and S. J. Klebanoff, Chemotactic factor inactivation by the myeloperoxidase-hydrogen peroxide-halide system, Journal of Clinical Investigation, vol.64, issue.4, pp.913-920, 1979.

M. S. Cohen, R. E. Isturiz, H. L. Malech, R. K. Root, C. M. Wilfert et al., Fungal infection in chronic granulomatous disease: the importance of the phagocyte in defense against fungi, American Journal of Medicine, vol.71, issue.1, pp.59-66, 1981.

T. Cole, M. S. Pearce, A. J. Cant, C. M. Cale, D. Goldblatt et al., Clinical outcome in children with chronic granulomatous disease managed conservatively or with hematopoietic stem cell transplantation, Journal of Allergy and Clinical Immunology, vol.132, issue.5, pp.1150-1155, 2013.

R. J. Collman and J. D. Dickerman, Corticosteroids in the managementof cystitis secondary to chronic granulomatous disease, Pediatrics, vol.85, issue.2, pp.219-221, 1990.

D. H. Craig, S. K. Chapman, and S. Daff, Calmodulin activates electron transfer through neuronal NO synthase reductase domain by releasing an NADPH-dependent conformational lock, Journal of Biological Chemistry, vol.277, issue.37, pp.33987-33994, 2002.
DOI : 10.1074/jbc.m203118200

URL : http://www.jbc.org/content/277/37/33987.full.pdf

J. F. Cuny, F. Chauvel, J. L. Schmutz, P. Bordigoni, M. Weber et al., Eruption « pseudo-lupique » chez une mère transmettrice de la granulomatose septique chronique liée à l'X, Annales de Dermatologie et de Vénérologie, vol.117, issue.10, pp.713-718, 1990.

R. N. Danziger, A. T. Goren, J. Becker, J. M. Greene, and S. D. Douglas, Outpatient management with oral corticosteroid therapy for obstructive conditions in chronic granulomatous disease, Journal of Pediatrics, vol.122, issue.2, pp.303-305, 1993.

J. Dekker, M. De-boer, and D. Roos, Gene-scan method for the recognition of carriers and patients with p47(phox)deficient autosomal recessive chronic granulomatous disease, Experimental Hematology, vol.29, issue.11, pp.1319-1325, 2001.

B. De-pauw, T. J. Walsh, J. P. Donnelly, D. A. Stevens, J. E. Edwards et al., Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group, Clinical Infectious Disease, vol.46, issue.12, pp.1813-1821, 2008.

S. S. De-ravin, N. Naumann, E. W. Cowen, J. Friend, D. Hilligoss et al., Chronic granulomatous disease as a risk factor for autoimmune disease, Journal of Allergy and Clinical Immunology, vol.122, issue.6, pp.1097-1103, 2008.

J. A. Dilworth and G. L. Mandell, Adults with chronic granulomatous disease of childhood, American Journal of Medicine, vol.63, issue.2, pp.233-243, 1977.

M. C. Dinauer, M. A. Gifford, N. Pech, L. L. Li, and P. Emshwiller, Variable correction of host defense following gene transfer and bone marrow transplantation in murine X-linked chronic granulomatous disease, Blood, vol.97, issue.12, pp.3738-3745, 2001.

M. C. Dinauer, E. A. Pierce, G. Bruns, J. T. Curnutte, and S. H. Orkin, Human neutrophil cytochrome b light chain (p22phox) : gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease, The Journal of Clinical Investigation, vol.86, issue.5, pp.1729-1737, 1990.
DOI : 10.1172/jci114898

URL : http://www.jci.org/articles/view/114898/files/pdf

M. C. Dinauer, E. A. Pierce, R. W. Erickson, T. J. Muhlebach, H. Messner et al., Point mutation in the cytoplasmic domain of neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease, Proceedings of the National Academy of Sciences of the USA, vol.88, issue.24, pp.11231-11235, 1991.

S. E. Dorman, S. V. Guide, P. S. Conville, E. S. Decarlo, H. L. Malech et al., Nocardia infection in chronic granulomatous disease, Clinical Infectious Diseases, vol.35, issue.4, pp.390-394, 2002.

B. Dunogué, B. Pilmis, N. Mahlaoui, C. Elie, F. Fouyssac et al., Devenir des patients atteints de granulomatose septique chronique à l'âge adulte. Une étude rétrospective nationale de 80 cas, La Revue de Médecine Interne, vol.35, issue.1, p.46, 2014.

J. W. Eckert, S. L. Abramson, J. Starke, and M. L. Brandt, The surgical implications of chronic granulomatous disease
DOI : 10.1016/s0002-9610(99)80167-6

, American Journal of Surgery, vol.169, issue.3, pp.320-323, 1995.

A. Emmendorffer, M. Nakamura, G. Rothe, K. Spiekermann, M. L. Lohmannmatthes et al., Evaluation of flow cytometric methods for diagnosis of chronic granulomatous disease variants under routine laboratory conditions, Cytometry, vol.18, issue.3, pp.147-155, 1994.

A. Etzioni, Immune deficiency and autoimmunity, Autoimmunity Reviews, vol.2, issue.6, pp.364-369, 2003.

, One of three successfully treated CGD patients in a Swiss-German gene therapy trial died due to his underlying disease: a position statement from the European Society of Gene Therapy (ESGT), The Journal of Gene Medicine, vol.8, issue.12, p.1435, 2006.

R. A. Ezekowitz, M. C. Dinauer, H. S. Jaffe, S. H. Orkin, and P. E. Newburger, Partial correction of the phagocyte defect in patients with X-linked chronic granulomatous disease by subcutaneous interferon gamma, New England Journal of Medicine, vol.319, issue.3, pp.146-151, 1988.

E. L. Falcone and S. M. Holland, Invasive fungal infection in chronic granulomatous disease: insights into pathogenesis and management, Current Opinion in Infectious Diseases, vol.25, issue.6, pp.658-669, 2012.
DOI : 10.1097/qco.0b013e328358b0a4

S. Fanconi, R. Seger, J. Gmür, U. Willi, G. Schaer et al., Surgery and granulocyte transfusion for life threatening infection in chronic granulomatous disease, Helvetica Paediatrica Acta, vol.40, issue.4, pp.277-284, 1985.

J. J. Feld, N. Hussain, E. C. Wright, D. E. Kleiner, J. H. Hoofnagle et al., Hepatic involvement and portal hypertension predict mortality in chronic granulomatous disease, Gastroenterology, vol.134, issue.7, pp.1917-1926, 2008.
DOI : 10.1053/j.gastro.2008.02.081

URL : http://europepmc.org/articles/pmc2583937?pdf=render

J. K. Femling, V. V. Cherny, D. Morgan, B. Rada, A. P. Davis et al., The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels, The Journal of General Physiology, vol.127, issue.6, pp.659-672, 2006.

M. Fines and R. Leclercq, Activity of linezolid against Gram-positive cocci possessing genes conferring resistance to protein synthesis inhibitors, Journal of Antimicrobial Chemotherapy, vol.45, issue.6, pp.797-802, 2000.

A. Finn, N. Hadzic, G. Morgan, S. Strobel, and R. J. Levinsky, Prognosis of chronic granulomatous disease, Archives of Disease in Childhood, vol.65, issue.9, pp.942-945, 1990.
DOI : 10.1136/adc.65.9.942

URL : https://adc.bmj.com/content/archdischild/65/9/942.full.pdf

A. Fischer, A. W. Segal, R. A. Seger, and R. S. Weening, The management of granulomatous disease, European Journal of Pediatrics, vol.152, issue.11, pp.896-899, 1993.

J. Fleurette, Les flores microbiennes commensales de la peau et des muqueuses, pp.362-403, 1995.

C. S. Foote and E. L. Clennan, Properties and reactions of singlet dioxygen. In: Active oxygen in chemistry, Blackie Academic & Professional, pp.104-140, 1995.

U. Francke, H. D. Ochs, B. De-martinville, J. Giacalone, V. Lindgren et al., Minor Xp 21 chromosome deletion in a male associated with expression of Duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa and Mc Leod syndrome, The American Journal of Human Genetics, vol.37, issue.2, pp.250-267, 1985.

J. I. Gallin, D. W. Alling, H. L. Malech, R. Wesley, D. Koziol et al., Itraconazole to prevent fungal infections in chronic granulomatous disease, New England Journal of Medicine, vol.348, issue.24, pp.2416-2422, 2003.
DOI : 10.1056/nejmoa021931

J. I. Gallin, H. L. Malech, D. A. Melnick, R. S. Weening, D. Roos et al., The International chronic granulomatous disease cooperative study group. A controlled trial of interferon gamma to prevent infection in chronic granulomatous disease, New England Journal of Medicine, vol.324, issue.8, pp.509-516, 1991.

R. Garcia-eulate, N. Hussain, T. Heller, D. Kleiner, H. L. Malech et al., CT and MRI of hepatic abscess in patients with chronic granulomatous disease, American Journal of Roentgenology, vol.187, issue.2, pp.482-490, 2006.

E. Ghibaudi and E. Laurenti, Unraveling the catalytic mechanism of lactoperoxidase and myeloperoxidase, European Journal of Biochemistry, vol.270, issue.22, pp.4403-4412, 2003.

F. K. Gmunder and R. A. Seger, Chronic granulomatous disease: mode of action of sulfamethoxazole/trimethoprim, Pediatric Research, vol.15, issue.12, pp.1533-1537, 1981.

D. Goldblatt, Current treatment options for chronic granulomatous disease, Expert Opinion on Pharmacotherapy, vol.3, issue.7, pp.857-863, 2002.
DOI : 10.1517/14656566.3.7.857

D. Goldblatt, Recent advances in chronic granulomatous disease, Journal of Infection, vol.69, issue.S1, pp.32-35, 2014.

D. Goldblatt, J. Butcher, and A. J. Thrasher, Russel-Eggitt I. Chorioretinal lesions in patients and carriers of chronic granulomatous disease, Journal of Pediatrics, vol.134, issue.6, pp.780-783, 1999.

M. Golioto, O. Connor, and J. B. , Esophageal dysmotility in an adult with chronic granulomatous disease, Journal of Clinical Gastroenterology, vol.33, issue.4, pp.330-332, 2001.

D. Greenberg, A. J. Ammann, D. W. Wara, and H. B. Kaltreider, Immunity to Aspergillus in patients with chronic granulomatous disease, Journal of Pediatrics, vol.90, issue.4, pp.601-603, 1977.

D. E. Greenberg, L. Ding, A. M. Zelazny, F. Stock, A. Wong et al., A novel bacterium associated with lymphadenitis in a patient with chronic granulomatous disease, PLoS Pathogens, vol.2, issue.4, p.28, 2006.

D. E. Greenberg, J. B. Goldberg, F. Stock, P. R. Murray, S. M. Holland et al., Recurrent Burkholderia infection in patients with chronic granulomatous disease: 11-year experience at a large referral center, Clinical Infectious Diseases, vol.48, issue.11, pp.1577-1579, 2009.

D. E. Greenberg, A. R. Shoffner, A. M. Zelazny, M. E. Fenster, K. A. Zarember et al., Recurrent Granulibacter bethesdensis infections and chronic granulomatous disease, Emerging Infectious Diseases, vol.16, issue.9, pp.1341-1348, 2010.

V. Guérin-faublée and Y. Brun, La résistance aux antibiotiques chez les staphylocoques d'origine animale. Revue de Médecine Vétérinaire, vol.150, pp.299-312, 1999.

T. Gungor, I. Engel-bicik, G. Eich, U. V. Willi, D. Nadal et al., Diagnostic and therapeutic impact of whole body positron emission tomography using fluorine-18-fluoro-2-deoxy-D-glucose in children with chronic granulomatous disease, Archives of Disease in Childhood, vol.85, issue.4, pp.341-345, 2001.

T. Gungor, J. Halter, A. Klink, S. Junge, K. D. Stumpe et al., Successful low toxicity hematopoietic stem cell transplantation for high-risk adult chronic granulomatous disease patients, Transplantation, vol.79, issue.11, pp.1596-1606, 2005.

T. Gungor, P. Teira, M. Slatter, G. Stussi, P. Stepensky et al., Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study, Lancet, vol.383, issue.9915, pp.436-448, 2014.

D. Haemmerich and B. J. Wood, Hepatic radiofrequency ablation at low frequencies preferentially heats tumour tissue, International Journal of Hyperthermia, vol.22, issue.7, pp.563-574, 2006.

T. Hamasaki, T. Sakano, M. Kobayashi, N. Sakura, K. Ueda et al., Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotriene B4 via NADPH oxidase-dependent mechanism, European Journal of Clinical Investigation, vol.19, issue.4, pp.404-411, 1989.

S. Hamzaoui-b'chir, T. Larbi, A. Ouni, A. Jamoussi, B. Mutapha et al., Une granulomatose septique chronique compliquée d'une pneumocystose pulmonaire, Médecine et Maladies Infectieuses, vol.45, issue.10, pp.414-416, 2015.

T. Hasebe, A. Someya, and I. Nagaoka, Identification of a splice variant mRNA of p40phox, an NADPH oxidase component of phagocytes, FEBS Letters, vol.455, issue.3, pp.257-261, 1999.

, Haut Conseil de la Santé Publique-Vaccinations des personnes immunodéprimées ou aspléniques : Recommandations. 2012 pp 106-107 + 119 et Age optimal de vaccination par le BCG chez les nourrissons, 201721.

A. P. Haynes and J. Fletcher, Neutrophil function tests, Bailliere's Clinical Haematology, vol.3, issue.4, pp.871-887, 1990.

W. R. Henderson and S. J. Klebanoff, Leukotriene production and inactivation by normal, chronic granulomatous disease and myeloperoxidase-deficient neutrophils, The Journal of Biological Chemistry, vol.258, issue.22, pp.13522-13527, 1983.

R. Herbrecht, D. W. Denning, T. F. Patterson, J. E. Bennett, R. E. Greene et al., Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis, New England Journal of Medicine, vol.347, issue.6, pp.408-415, 2002.

P. G. Heyworth, J. T. Curnutte, R. J. Noack, D. Roos, D. Van-koppen et al., Hematologically important mutations: X-linked chronic granulomatous disease (second update), Blood Cells, Molecules and Diseases, vol.27, issue.1, pp.16-26, 2001.

P. G. Heyworth, D. Noack, and A. R. Cross, Identification of a novel NCF-1 (p47-phox) pseudogene not containing the signature GT deletion: significance for A47 0 chronic granulomatous disease carrier detection, Blood, vol.100, issue.5, pp.1845-1851, 2002.

K. Hiramatsu, Vancomycin resistance in staphylococci, Drug Resistance Updates, vol.1, issue.2, pp.135-150, 1998.

K. Hiramatsu and H. Hanaki, Glycopeptide resistance in staphylococci, Current Opinion in Infectious Diseases, vol.11, issue.6, pp.653-658, 1998.

S. M. Holland, Chronic Granulomatous Disease, Clinical Reviews in Allergy & Immunology, vol.38, issue.1, pp.3-10, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00809510

S. M. Holland, Chronic granulomatous disease: from a fatal disease to a curable one, Primary immunodeficiency disorders: a historic and scientific perspective, pp.151-70, 2014.

B. Holmes, P. G. Quie, D. B. Windhorst, and R. A. Good, Fatal granulomatous disease of childhood. An inborn abnormality of phagocytic function, Lancet, vol.1, issue.7449, pp.1225-1228, 1966.

M. E. Horwitz, A. J. Barrett, M. R. Brown, C. S. Carter, R. Childs et al., Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a Tcell-depleted hematopoietic allograft, New England Journal of Medicine, vol.344, issue.12, pp.881-888, 2001.

E. Hsich, B. H. Segal, P. J. Pagano, F. E. Rey, B. Paigen et al., Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase, Circulation, vol.101, issue.11, pp.1234-1236, 2000.

N. Hussain, J. J. Feld, D. E. Kleiner, J. H. Hoofnagle, R. Garcia-eulate et al., Hepatic abnormalities in patients with chronic granulomatous disease, Hepatology, vol.45, issue.3, pp.675-683, 2007.

F. Ishibashi, H. Nunoi, F. Endo, I. Matsuda, and S. Kanegasaki, Statistical and mutational analysis of chronic granulomatous disease in Japan with special reference to gp91-phox and p22-phox deficiency, Human Genetics, vol.106, issue.5, pp.473-481, 2000.

C. A. Janeway, J. Craig, M. Davidson, W. Downey, D. Gitlin et al., Hypergammaglobulinemia associated with severe, recurrent and chronic non-specific infection, American Journal of Diseases of Children, vol.88, pp.388-392, 1954.

L. B. Johnson and C. A. Kauffman, Voriconazole: a new triazole antifungal agent, Clinical Infectious Diseases, vol.36, issue.5, pp.630-637, 2003.

R. B. Johnston and R. L. Baehner, Chronic granulomatous disease: correlation between pathogenesis and clinical findings, Pediatrics, vol.48, issue.5, pp.730-739, 1971.

R. B. Johnston and R. L. Baehner, Improvement of bactericidal activity in leukocytes from patients with chronic granulomatous disease, Blood Journal, vol.35, issue.3, pp.350-355, 1970.

R. B. Johnston and J. S. Mcmurry, Chronic familial granulomatosis. Report of five cases and review of the literature

, American Journal of Diseases of Children, vol.114, issue.4, pp.370-378, 1967.

L. B. Jones, P. Mc-grogan, T. J. Flood, A. R. Gennery, L. Morton et al., Special article: chronic granulomatous disease in the United Kingdom and Ireland: a comprehensive national patientbased registry, Clinical and Experimental Immunology, vol.152, issue.2, pp.211-218, 2008.

M. E. Jones, M. R. Visser, M. Klootwijk, P. Heisig, J. Verhoef et al., Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linezolid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacinresistant and-susceptible Staphylococcus aureus strains, Antimicrobial Agents and Chemotherapy, vol.43, issue.2, pp.421-423, 1999.

S. Jonsson, R. J. Wallace, S. I. Hull, and D. M. Musher, Recurrent Nocardia pneumonia in an adult with chronic granulomatous disease, The American Review of Respiratory Disease, vol.133, issue.5, pp.932-934, 1986.

M. Jublin, D. L. Bartlett, D. N. Danforth, H. Kauffman, J. I. Gallin et al., Hepatic abscess in patients with chronic granulomatous disease, Annals of Surgery, vol.235, issue.3, pp.383-391, 2002.

E. L. Kaplan, T. Laxdal, and P. G. Quie, Studies of polymorphonuclear leukocytes from patients with chronic granulomatous disease of childhood: bactericidal capacity for streptococci, Pediatrics, vol.41, issue.3, pp.591-599, 1968.

R. T. Kenney, H. L. Malech, N. D. Epstein, R. L. Roberts, and T. L. Leto, Characterization of the p67phox gene: genomic organisation and restriction fragment length polymorphism analysis for prenatal diagnosis in chronic granulomatous disease, Blood, vol.82, issue.12, pp.3739-3744, 1993.

K. T. Kishida, C. A. Hoeffer, D. Hu, M. Pao, S. M. Holland et al., Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease, Molecular and Cellular Biology, vol.26, issue.15, pp.5908-5920, 2006.

S. J. Klebanoff, Myeloperoxidase-halide-hydrogen peroxide antibacterial system, Journal of Bacteriology, vol.95, issue.6, pp.2131-2138, 1968.

H. Kono, I. Rusyn, M. Yin, E. Gäbele, S. Yamashina et al., NADPH oxidase-derived free radicals are key oxidants in alcoholinduced liver disease, The Journal of Clinical Investigation, vol.106, issue.7, pp.867-872, 2000.

S. H. Korman, P. Lebensart, and Y. Shvil, Hydronephrosis caused by ureteric obstruction in chronic granulomatous disease: successful treatment by percutaneous nephrostomy and antibiotic therapy, Journal of Pediatrics, vol.116, issue.5, pp.740-742, 1990.

D. B. Kuhns, W. G. Alvord, T. Heller, J. J. Feld, K. M. Pike et al., Residual NADPH oxidase and survival in chronic granulomatous disease, The New England journal of Medicine, vol.363, issue.27, pp.2600-2610, 2010.

G. M. Lazarus and H. C. Neu, Agents responsible for infection in chronic granulomatous disease of childhood, Journal of Pediatrics, vol.86, issue.3, pp.415-417, 1975.

P. J. Leavey, G. Thurman, and D. R. Ambruso, Functional characteristics of neutrophils collected and stored after administration of G-CSF, Transfusion, vol.40, issue.4, pp.414-419, 2000.

B. W. Lee and H. K. Yap, Polyarthritis resembling juvenile rheumatoid arthritis in a girl with chronic granulomatous disease, Arthritis & Rheumatology, vol.37, issue.5, pp.773-776, 1994.

J. W. Leiding, A. F. Freeman, B. E. Marciano, V. L. Anderson, G. Uzel et al., Corticosteroid therapy for liver abscess in chronic granulomatous disease, Clinical Infectious Diseases, vol.54, issue.5, pp.694-700, 2012.
DOI : 10.1093/cid/cir896

URL : https://academic.oup.com/cid/article-pdf/54/5/694/929006/cir896.pdf

J. W. Leiding and S. M. Holland, Chronic granulomatous disease, Gene Reviews, 1993.

J. A. Lekstrom-himes, S. M. Holland, E. S. Decarlo, J. Miller, S. F. Leitman et al., Treatment with intralesional granulocyte instillations and interferon-gamma for a patient with chronic granulomatous disease and multiple hepatic abscesses, Clinical Infectious Diseases, vol.19, issue.4, pp.770-773, 1994.
DOI : 10.1093/clinids/19.4.770

T. L. Leto, K. J. Lomax, B. D. Volpp, H. Nunoi, J. Sechler et al., Cloning of a 67-kD neutrophil oxidase factor with similarity to a non-catalytic region of p60c-src, Science, vol.248, issue.4956, pp.727-730, 1990.

J. Leusen, B. G. Bolscher, P. M. Hilarius, R. S. Weening, W. Kaulfersch et al., 156ProGln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox, The Journal of Experimental Medicine, vol.180, issue.6, pp.2329-2334, 1994.

J. Leusen, A. De-klein, P. M. Hilarius, A. Ahlin, J. Palmblad et al., Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease, The Journal of Experimental Medicine, vol.184, issue.4, pp.1243-1249, 1996.

S. Levine, V. V. Smith, M. Malone, and N. J. Sebire, Histopathological features of chronic granulomatous disease (CGD) in childhood, Histopathology, vol.47, issue.5, pp.508-516, 2005.

J. G. Liese, V. Jendrossek, A. Jansson, T. Petropoulou, S. Kloos et al., Chronic granulomatous disease in adults, Lancet, vol.347, issue.8996, pp.220-223, 1996.

J. G. Liese, S. Kloos, V. Jendrossek, T. Petropoulou, U. Wintergerst et al., Long-term follow-up and outcome of 39 patients with chronic granulomatous disease, Journal of Pediatrics, vol.137, issue.5, pp.687-693, 2000.
DOI : 10.1067/mpd.2000.109112

A. Locatelli, M. C. Béné, S. Zuily, and K. Angioi-duprez, Atteintes ophtalmologiques dans la granulomatose septique chronique, Journal français d'ophtalmologie, vol.36, issue.9, pp.789-795, 2013.
DOI : 10.1016/j.jfo.2013.07.002

K. J. Lomax, T. L. Leto, H. Nunoi, J. I. Gallin, and H. L. Malech, Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease, Science, vol.245, issue.4916, pp.409-412, 1989.
DOI : 10.1126/science.2547247

URL : https://zenodo.org/record/1231014/files/article.pdf

F. C. Lopez, F. F. Luna, M. C. Delgado, I. I. De-la-rosa, S. Valdezate et al., Granulibacter bethesdensis isolated in a child patient with chronic granulomatous disease, Journal of Infection, vol.57, issue.3, pp.275-277, 2008.

M. Lublin, D. L. Bartlett, D. N. Danforth, H. Kauffman, J. I. Gallin et al., Hepatic abscess in patients with chronic granulomatous disease, Annals of Surgery, vol.235, issue.3, pp.383-391, 2002.
DOI : 10.1097/00000658-200203000-00010

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422444/pdf

S. O. Lugo-reyes, F. Suarez, R. M. Herbigneaux, H. Pacquement, Y. Réguerre et al., Hodgkin lymphoma in two children with chronic granulomatous disease, Journal of Allergy Clinical Immunology, vol.127, issue.2, pp.543-544, 2011.

N. Mahlaoui, F. Suarez, O. Hermine, O. Lortholary, S. Blanche et al., Granulomatose septique chronique : ce que nous savons et ce que nous ne savons pas encore, Archives de Pédiatrie, vol.18, issue.5S1, pp.234-235, 2011.
DOI : 10.1016/s0929-693x(11)71053-3

H. L. Malech, Chronic granulomatous disease, Clinical hematology. Philadelphia : Mosby, pp.748-57, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00809510

H. L. Malech, U. Choi, and S. Brenner, Progress toward effective gene therapy for chronic granulomatous disease
DOI : 10.1086/513852

URL : https://academic.oup.com/jid/article-pdf/179/Supplement_2/S318/17991028/179-Supplement_2-S318.pdf

, Japanese Journal of Infectious Diseases, vol.57, issue.5, pp.27-28, 2004.

H. L. Malech, P. B. Maples, N. Whiting-theobald, G. F. Linton, S. Sekhsaria et al., Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease, Proceedings of the National Academy of Sciences of the USA, vol.94, issue.22, pp.12133-12138, 1997.

G. L. Mandell and E. W. Hook, Leukocyte bactericidal activity in chronic granulomatous disease: correlation of bacterial hydrogen peroxide production and susceptibility to intracellular killing, Journal of Bacteriology, vol.100, issue.1, pp.531-532, 1969.

B. E. Marciano, S. D. Rosenzweig, D. E. Kleiner, V. L. Anderson, D. N. Darnell et al., Gastrointestinal involvement in chronic granulomatous disease, Pediatrics, vol.114, issue.2, pp.462-468, 2004.

B. E. Marciano, C. Spalding, A. Fitzgerald, D. Mann, T. Brown et al., Common severe infections in chronic granulomatous disease, Clinical Infectious Diseases, vol.60, issue.8, pp.1176-1183, 2015.
DOI : 10.1093/cid/ciu1154

URL : https://academic.oup.com/cid/article-pdf/60/8/1176/7451728/ciu1154.pdf

D. M. Margolis, D. A. Melnick, D. W. Alling, and J. I. Gallin, Trimethoprim-sulfamethoxazole prophylaxis in the management of chronic granulomatous disease, The Journal of Infectious Diseases, vol.162, issue.3, pp.723-726, 1990.

D. J. Marks, K. Miyagi, F. Z. Rahman, M. Novelli, S. L. Bloom et al., Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease, The American Journal of Gastroenterology, vol.104, issue.1, pp.117-124, 2009.

R. R. Marples, Experimental staphylococcal infection in humans, pp.73-81, 1981.

B. Martire, R. Rondelli, A. Soresina, C. Pignata, T. Broccoletti et al., Clinical features, long-term follow-up and outcome of a large cohort of patients with chronic granulomatous disease: an Italian multicenter study, Clinical Immunology, vol.126, issue.2, pp.155-164, 2008.

L. J. Martyn, H. W. Lischner, A. J. Pileggi, and R. D. Harley, Chrorioretinal lesions in familial chronic granulomatous disease of childhood, Transactions of the American Ophthalmological Society, vol.69, pp.84-112, 1971.
DOI : 10.1016/0002-9394(72)90070-0

URL : http://europepmc.org/articles/pmc1310407?pdf=render

J. May, K. Shannon, A. King, and G. French, Glycopeptide tolerance in Staphylococcus aureus, Antimicrobial Agents Chemotherapy, vol.42, issue.2, pp.189-197, 1998.
DOI : 10.1093/jac/42.2.189

URL : https://academic.oup.com/jac/article-pdf/42/2/189/9838044/420189.pdf

M. Migliavacca, A. Assanelli, F. Ferrua, M. P. Cicalese, A. Biffi et al., Pioglitazone as a novel therapeutic approach in chronic granulomatous disease, Journal of Allergy and Clinical immunology, vol.137, issue.6, pp.1913-1915, 2016.
DOI : 10.1016/j.jaci.2016.01.033

URL : https://doi.org/10.1016/j.jaci.2016.01.033

E. L. Mills, K. S. Rholl, and P. G. Quie, X-linked inheritance in females with chronic granulomatous disease, Journal of Clinical Investigation, vol.66, issue.2, pp.332-340, 1980.
DOI : 10.1172/jci109861

URL : http://www.jci.org/articles/view/109861/files/pdf

U. Modlich, J. Bohne, M. Schmidt, C. Von-kalle, S. Knoss et al., Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity, Blood, vol.108, issue.8, pp.2545-2553, 2006.
DOI : 10.1182/blood-2005-08-024976

URL : http://www.bloodjournal.org/content/bloodjournal/108/8/2545.full.pdf

D. E. Morgenstern, M. A. Gifford, L. L. Li, C. M. Doerschuk, and M. C. Dinauer, Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus, The Journal of Experimental Medicine, vol.185, issue.2, pp.207-218, 1997.

R. Mouy, A. Fischer, E. Vilmer, R. Seger, and C. Griscelli, Incidence, severity and prevention of infections in chronic granulomatous disease, Journal of Pediatrics, vol.114, issue.4Pt1, pp.555-560, 1989.
DOI : 10.1016/s0022-3476(89)80693-6

R. Mouy, J. C. Ropert, J. Donadieu, P. Hubert, J. De-blic et al., Granulomatose septique chronique révélée par une aspergillose pulmonaire néonatale, Archives de Pédiatrie, vol.2, issue.9, pp.861-864, 1995.
DOI : 10.1016/0929-693x(96)81264-4

R. Mouy, F. Veber, S. Blanche, J. Donadieu, R. Brauner et al., Long-term itraconazole prophylaxis against Aspergillus infection in thirty-two patients with chronic granulomatous disease, Journal of Pediatrics, vol.125, issue.6Pt1, pp.998-1003, 1994.
DOI : 10.1016/s0022-3476(05)82023-2

R. Mouy, E. Vilmer, and C. Griscelli, Infection aspergillaire et granulomatose septique chronique. Médecine et Maladies Infectieuses, vol.14, pp.566-571, 1984.
DOI : 10.1016/s0399-077x(84)80009-8

E. H. Moylett, S. E. Pacheco, B. A. Brown-elliott, T. R. Perry, E. S. Buescher et al., Clinical experience with linezolid for the treatment of nocardia infection, Clinical Infectious Diseases, vol.36, issue.3, pp.313-318, 2003.

T. J. Muhlebach, J. Gabay, C. F. Nathan, C. Erny, G. Dopfer et al., Treatment of patients with chronic granulomatous disease with recombinant human interferon-gamma does not improve neutrophil oxidative metabolism, cytochrome b558 content or levels of four anti-microbial proteins, Clinical and Experimental Immunology, vol.88, issue.2, pp.203-206, 1992.

H. W. Murray, B. Y. Rubin, and C. D. Rothermel, Killing of intracellular Leishmania donovani by lymphokinestimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokine, The journal of Clinical Investigation, vol.72, issue.4, pp.1506-1510, 1983.
DOI : 10.1172/jci111107

URL : http://www.jci.org/articles/view/111107/files/pdf

M. A. Myers, L. C. Mcphail, and R. Snyderman, Redistribution of protein kinase C activity in human monocytes: correlation with activation of the respiratory burst, Journal of Immunology, vol.135, issue.5, pp.3411-3416, 1985.

L. Nalidini, Inserting optimism into gene therapy, Nature Medicine, vol.12, issue.4, pp.386-389, 2006.

H. J. Neijens, J. Frenkel, D. Muinck-keizer-schrama, S. M. Dzoljic-danilovic, G. Meradji et al., Invasive Aspergillus infection in chronic granulomatous disease: treatment with itraconazole, Journal of Pediatrics, vol.115, issue.6, pp.1016-1019, 1989.
DOI : 10.1016/s0022-3476(89)80762-0

P. E. Newburger, H. J. Cohen, S. B. Rothchild, J. C. Hobbins, S. E. Malawista et al., Prenatal diagnosis of chronic granulomatous disease, The New England Journal of Medicine, vol.300, issue.4, pp.178-181, 1979.

P. E. Newburger, D. G. Skalnik, P. J. Hopkins, E. A. Eklund, and J. T. Curnutte, Mutation in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558, The Journal of Clinical Investigation, vol.94, issue.3, pp.1205-1211, 1994.

T. I. Nicas, M. L. Zeckel, and D. K. Braun, Beyond vancomicin: new therapies to meet the challenge of glycopeptide resistance, Trends in Microbiology, vol.5, issue.6, pp.240-249, 1997.

D. Noack, J. Rae, A. R. Cross, B. A. Ellis, P. E. Newburger et al., Autosomal recessive chronic granulomatous disease caused by defects in NCF-1, the gene encoding the phagocyte p47-phox: mutation not arising in the NCF-1 pseudogenes, Blood, vol.97, issue.1, pp.305-311, 2001.

N. Noel, N. Mahlaoui, S. Blanche, F. Suarez, H. Coignard-biehler et al., Efficacy and safety of thalidomide in patients with inflammatory manifestations of chronic granulomatous disease: A retrospective case series, Journal of Allergy and Clinical Immunology, vol.132, issue.4, pp.997-1000, 2013.
URL : https://hal.archives-ouvertes.fr/hal-00838579

H. D. Ochs and R. P. Igo, The NBT slide test: a simple screening method for detecting chronic granulomatous disease and female carriers, Journal of Pediatrics, vol.83, issue.1, pp.77-82, 1973.

M. G. Ott, M. Schmidt, K. Schwarzwaelder, S. Stein, U. Siler et al., Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1, Nature Medicine, vol.12, issue.4, pp.401-409, 2006.

M. G. Ott, R. A. Seger, S. Stein, U. Siler, D. Hoelzer et al., Advances in the treatment of chronic granulomatous disease by gene therapy, Current Gene Therapy, vol.7, issue.3, pp.155-161, 2007.

H. Ozsahin, M. Von-planta, I. Muller, H. C. Steinert, D. Nadal et al., Successful treatment of invasive aspergillosis in chronic granulomatous disease by bone marrow transplantation, granulocyte colony-stimulating factor-mobilized granulocytes, and liposomal amphotericin-B, Blood, vol.92, issue.8, pp.2719-2724, 1998.

C. A. Parkos, M. C. Dinauer, L. E. Walker, R. A. Allen, A. J. Jesaitis et al., Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b, Proceedings of the National Academy of Sciences of the USA, vol.85, issue.10, pp.3319-3323, 1988.

P. J. Patino, J. Rae, D. Noack, R. Erickson, J. Ding et al., Molecular characterization of autosomal recessive chronic granulomatous disease caused by a defect of the nicotinamide adenine dinucleotide phosphate (reduced form) oxidase component p67-phox, Blood, vol.94, issue.7, pp.2505-2514, 1999.

B. Paul and A. J. Sbarra, The role of the phagocyte in host-parasite interactions. 13. The direct quantitative estimation of H 2 O 2 in phagocytizing cells, Biochimica Biophysica Acta, vol.156, issue.1, pp.168-178, 1968.

F. K. Pedersen, K. S. Johansen, J. Rosenkvist, I. Tygstrup, and N. H. Valerius, Refractory Pneumocystis carinii infection in chronic granulomatous disease : successful treatment with granulocytes, Pediatrics, vol.64, issue.6, pp.935-938, 1979.

J. R. Perfect, D. V. Savani, and D. T. Durack, Uptake of itraconazole by alveolar macrophages, Antimicrobial Agents and Chemotherapy, vol.37, issue.4, pp.903-904, 1993.

M. Von-planta, H. Ozsahin, H. Schroten, U. G. Stauffer, and R. A. Seger, Greater omentum flaps and granulocyte transfusions as combined therapy of liver abscess in chronic granulomatous disease, European Journal of Pediatric Surgery, vol.7, issue.4, pp.234-236, 1997.

H. W. Pogrebniak, J. I. Gallin, H. L. Malech, A. R. Baker, C. A. Moskaluk et al., Surgical management of pulmonary infections in chronic granulomatous disease of childhood, Annals of Thoracic Surgery, vol.55, issue.4, pp.844-849, 1993.

C. D. Porter, M. H. Parkar, R. J. Levinsky, M. Collins, and C. Kinnon, X-linked chronic granulomatous disease: correction of NADPH oxidase defect by retrovirus-mediated expression of gp91-phox, Blood, vol.82, issue.7, pp.2196-2202, 1993.

P. G. Quie, E. L. Kaplan, A. R. Page, F. L. Gruskay, and S. E. Malawista, Defective polymorphnuclear-leukocyte function and chronic granulomatous disease in two femal children, The New England Journal of Medicine, vol.278, issue.18, pp.976-980, 1968.

P. G. Quie, J. Verhoef, Y. Kim, and P. K. Peterson, Host determinants of staphylococcal infections, pp.83-93, 1981.

P. G. Quie, J. G. White, B. Holmes, and R. A. Good, In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood, The Journal of Clinical Investigation, vol.46, issue.4, pp.668-679, 1967.

J. Rae, P. E. Newburger, M. C. Dinauer, D. Noack, P. J. Hopkins et al., X-linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory burst oxidase

, American Journal of Human Genetics, vol.62, issue.6, pp.1320-1331, 1998.

E. P. Reeves, H. Lu, H. L. Jacobs, C. G. Messina, S. Bolsover et al., Killing activity of neutrophils in mediated through activation of proteases by K+ flux, Nature, vol.416, issue.6878, pp.291-297, 2002.

J. Reichenbach, U. Lopatin, N. Mahlaoui, B. Beovic, U. Siler et al., Actinomyces in chronic granulomatous disease: an emerging and unanticipated pathogen, Clinical Infectious Diseases, vol.49, issue.11, pp.1703-1710, 2009.

L. De-repentigny, J. Ratelle, J. M. Leclerc, G. Cornu, E. M. Sokal et al., Repeated-dose pharmacokinetics of an oral solution of itraconazole in infants and children, Antimicrobial Agents and Chemotherapy, vol.42, issue.2, pp.404-408, 1998.

J. E. Repine, J. G. White, C. C. Clawson, and B. M. Holmes, Effects of Phorbol Myristate Acetate on the metabolism and ultrastructure of neutrophils in chronic granulomatous disease, The Journal of Clinical Investigation, vol.54, issue.1, pp.83-90, 1974.

B. Richard and J. R. Johnston, Screening test for the diagnosis of chronic granulomatous disease, Pediatrics, vol.43, issue.1, pp.122-124, 1969.

C. Rivat, G. Santilli, H. B. Gaspar, and A. J. Thrasher, Gene therapy for primary immunodeficiencies, Human Gene Therapy, vol.23, issue.7, pp.668-675, 2012.

J. Roesler, S. Brenner, A. A. Bukovsky, N. Whiting-theobald, T. Dull et al., Third-generation, self-inactivating gp91(phox) lentivector corrects the oxidase defect in NOD/SCID mouse-repopulating peripheral blood-mobilized CD34+ cells from patients with X-linked chronic granulomatous disease, Blood, vol.100, issue.13, pp.4381-4390, 2002.

J. Roesler, J. T. Curnutte, R. J. Barrett, D. Patino, P. Chanock et al., Recombination events between the p47-phox gene and its highly homologous pseudogenes are the main cause of autosomal recessive chronic granulomatous disease, Blood, vol.95, issue.6, pp.2155-2156, 2000.

J. Roesler, A. Koch, G. Porksen, V. Bernuth, H. Brenner et al., Benefit assessment of preventive medical check-ups in patients suffering from chronic granulomatous disease (CGD), Journal of Evaluation in Clinical Practice, vol.11, issue.6, pp.513-521, 2005.

D. Roos, M. De-boer, M. Y. Köker, J. Dekker, V. Singh-gupta et al., Chronic granulomatous disease caused by mutations other than the common GT deletion in NCF1, the gene encoding the p47phox component of the phagocyte NADPH oxidase, Human Mutation, vol.27, issue.12, pp.1218-1229, 2006.

D. Roos, D. Boer, M. Kuribayashi, F. Meishchl, C. Weening et al., Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease, Blood, vol.87, issue.5, pp.1663-81, 1996.

A. Rosen-wolff, W. Soldan, K. Heyne, J. Bickhardt, M. Gahr et al., Increased susceptibility of a carrier of Xlinked chronic granulomatous disease (CGD) to Aspergillus fumigatus infection associated with age-related skewing of lyonization, Ann Hematol, vol.80, issue.2, pp.113-115, 2001.

S. D. Rosenzweig, Inflammatory manifestations in chronic granulomatous disease, Journal of Clinical Immunology, vol.28, issue.S1, pp.67-72, 2008.

J. R. Rosh, H. B. Tang, L. Mayer, G. Groisman, S. K. Abraham et al., Treatment of intractable gastrointestinal manifestations of chronic granulomatous disease with cyclosporine, Journal of Pediatrics, vol.126, issue.1, pp.143-145, 1995.

J. P. Ross, S. M. Holland, V. J. Gill, E. S. Decarlo, and J. I. Gallin, Severe Burkholderia (Pseudomonas) gladioli infection in chronic granulomatous disease: report of two successfully treated cases, Clinical Infectious Diseases, vol.21, issue.5, pp.1291-1293, 1995.

F. Rossi, D. Romeo, and P. Patriarca, Mechanism of phagocytosis-associated oxidative metabolism in polymorphonuclear leucocytes and macrophages, Journal of Reticuloendothelium Society, vol.12, issue.2, pp.127-149, 1972.

B. L. Royer-pokora, L. M. Kunkel, A. P. Monaco, S. C. Goff, P. E. Newburger et al., Cloning the gene for an inherited disorder chronic granulomatous disease on the basis of its chromosomal location, Nature, vol.322, issue.6074, pp.32-38, 1986.

A. Rüggeberg, M. Deja, U. Kaisers, T. Steinmuller, U. Keske et al., Multiorganversagen bei septischer Granulomatose, Anaesthesist, vol.51, issue.9, pp.731-734, 2002.

R. A. Rupec, T. Petropoulou, B. H. Belohradsky, M. Walchner, J. G. Liese et al., Lupus erythematosus tumidus and chronic discoid lupus erythematosus in carriers of X-linked chronic granulomatous disease

, European Journal of Dermatology, vol.10, issue.3, pp.184-189, 2000.

I. Rusyn, M. B. Kadiiska, A. Dikalova, H. Kono, M. Yin et al., Phthalates rapidly increase production of reactive oxygen species in vivo: role of Kupffer cells, Molecular Pharmacology, vol.59, issue.4, pp.744-750, 2001.

S. Sagami, S. Tanaka, Y. Ueno, K. Nagai, R. Hayashi et al., Colonic manifestations of chronic granulomatous disease
DOI : 10.1016/j.gie.2016.03.498

, Gastrointestinal Endoscopy, vol.83, issue.5, p.307, 2016.

H. Salvator, N. Mahlaoui, E. Catherinot, E. Rivaud, B. Pilmis et al.,

, European Respiratory Journal, vol.45, issue.6, pp.1613-1623, 2015.

L. D. Samuels, Liver Scans in chronic granulomatous disease of childhood, Pediatrics, vol.48, issue.1, pp.41-50, 1971.

W. J. Sandborn, Optimizing anti-tumor necrosis factor strategies in inflammatory bowel disease, Current Gastroenterology Reports, vol.5, issue.6, pp.501-505, 2003.
DOI : 10.1007/s11894-003-0040-8

A. J. Sbarra and M. L. Karnovsky, The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes, Journal of Biological Chemistry, vol.234, issue.6, pp.1355-1362, 1959.

J. Schaller, Illness resembling lupus erythematosus in mothers of boys with chronic granulomatous disease, Annals of Internal Medicine, vol.76, issue.5, pp.747-750, 1972.

M. G. Schäppi, V. V. Smith, D. Goldblatt, K. J. Lindley, and P. J. Milla, Colitis in chronic granulomatous disease, Archives of Disease in Childhood, vol.84, issue.2, pp.147-151, 2001.

B. H. Segal, T. L. Leto, J. I. Gallin, H. L. Malech, and S. M. Holland, Genetic, biochemical, and clinical features of chronic granulomatous disease, Medicine (Baltimore), vol.79, issue.3, pp.170-200, 2000.
DOI : 10.1097/00005792-200005000-00004

B. H. Segal, E. S. Decarlo, K. J. Kwon-chung, H. L. Malech, J. I. Gallin et al., Aspergillus nidulans infection in chronic granulomatous disease, Medicine (Baltimore), vol.77, issue.5, pp.345-354, 1998.
DOI : 10.1097/00005792-199809000-00004

B. H. Segal, L. A. Barnhart, V. L. Anderson, T. J. Walsh, H. L. Malech et al., Posaconazole as salvage therapy in patients with chronic granulomatous disease and invasive filamentous fungal infection, Clinical Infectious Diseases, vol.40, issue.11, pp.1684-1688, 2005.
DOI : 10.1086/430068

URL : https://academic.oup.com/cid/article-pdf/40/11/1684/1224121/40-11-1684.pdf

R. A. Seger, Modern management of chronic granulomatous disease, British Journal of Haematology, vol.140, issue.3, pp.255-266, 2008.
DOI : 10.1111/j.1365-2141.2007.06880.x

R. A. Seger, T. Gungor, B. H. Belohradsky, S. Blanche, P. Bordigoni et al., Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a Survey of the European Experience, Blood, vol.100, issue.13, pp.4344-4350, 1985.

B. L. Shapiro, P. E. Newburger, M. S. Klempner, and M. C. Dinauer, Chronic granulomatous disease presenting in a 69-yearold man, The New England Journal of Medicine, vol.325, issue.25, pp.1786-1790, 1991.

S. Siddiqui, V. L. Anderson, D. M. Hilligoss, M. Abinun, T. W. Kuijpers et al., Fulminant mulch pneumonitis: an emergency presentation of chronic granulomatous disease, Clinical Infectious Diseases, vol.45, issue.6, pp.673-681, 2007.
DOI : 10.1086/520985

URL : https://academic.oup.com/cid/article-pdf/45/6/673/796991/45-6-673.pdf

H. Sokol, F. Suarez, T. Meatchi, G. Malamut, M. A. Pocidalo et al., Thalidomide as a treatment for refractory chronic granulomatous disease colitis, The American Journal of Gastroenterology, vol.104, issue.4, p.1069, 2009.
DOI : 10.1038/ajg.2009.56

D. P. Speert, M. Bond, R. C. Woodman, and J. T. Curnutte, Infection with Pseudomonas cepacia in chronic granulomatous disease: role of nonoxidative killing by neutrophils in host defense, Journal of Infectious Diseases, vol.170, issue.6, pp.1524-1531, 1994.

M. J. Stasia, The X+ chronic granulomatous disease as a fabulous model to study the NADPH oxidase complex activation, Médecine Sciences, vol.23, issue.5, pp.526-532, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00382250

M. J. Stasia, P. Bordigoni, D. Floret, J. P. Brion, C. Bost-bru et al., Characterization of six novel mutations in the CYBB gene leading to different sub-types of X-linked chronic granulomatous disease, Human Genetics, vol.116, issue.1-2, pp.72-82, 2005.
URL : https://hal.archives-ouvertes.fr/hal-00382114

M. J. Stasia, P. Bordigoni, C. Martel, and F. Morel, A novel and unusual case of chronic granulomatous disease in a child with a homozygous 36-bp deletion in the CYBA gene (A22(0)) leading to the activation of a cryptic splice site in intron 4, Human Genetics, vol.110, issue.5, pp.444-450, 2002.

M. J. Stasia, J. P. Brion, J. Boutonnat, and F. Morel, Severe clinical forms of cytochrome b-negative chronic granulomatous disease (X91-) in 3 brothers with a point mutation in the promoter region of CYBB, Journal of Infectious Disease, vol.188, issue.10, pp.1593-1604, 2003.

M. J. Stasia, P. Cathebras, M. F. Lutz, and I. Durieu, Chronic-granulomatous disease, Revue de Médecine Interne, vol.30, issue.3, pp.221-232, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00382241

M. J. Stasia, B. Lardy, A. Maturana, P. Rousseau, C. Martel et al., Molecular and functional characterization of a new X-linked chronic granulomatous disease variant (X91+) case with a double missense mutation in the cytosolic gp91phox C-terminal tail, Biochimica et Biophysica Acta, vol.1586, issue.3, pp.316-330, 2002.

M. J. Stasia and X. J. Li, Genetic and immunopathology of chronic granulomatous disease. Nox enzymes in immune cells issue, Seminars in Immunopathology, vol.30, issue.3, pp.209-235, 2008.
DOI : 10.1007/s00281-008-0121-8

S. Stein, U. Siler, M. G. Ott, R. Seger, and M. Grez, Gene therapy for chronic granulomatous disease, Current Opinion in Molecular Therapeutics, vol.8, issue.5, pp.415-422, 2006.

D. F. Stroncek, K. Leonard, G. Eiber, H. L. Malech, J. I. Gallin et al., Alloimmunization after granulocyte transfusions, Transfusion, vol.36, pp.1009-1015, 1996.
DOI : 10.1046/j.1537-2995.1996.36111297091747.x

N. Suzuki, N. Hatakeyama, M. Yamamoto, N. Mizue, Y. Kuroiwa et al., Treatment of McLeod phenotype chronic granulomatous disease with reducedintensity conditioning and unrelated-donor umbilical cord blood transplantation, International Journal of Hematology, vol.85, issue.1, pp.70-72, 2007.
DOI : 10.1532/ijh9706129

C. Teahan, P. Rowe, P. Parker, N. Totty, and A. W. Segal, The X-linked CGD disease gene codes for the beta-chain of cytochrome b558, Nature, vol.327, issue.6124, pp.720-721, 1987.

A. Thrasher, C. M. Casimir, C. Kinnon, G. Morgan, A. W. Segal et al., Gene transfer to primary chronic granulomatous disease monocytes, Lancet, vol.346, issue.8967, pp.92-93, 1995.
DOI : 10.1016/s0140-6736(95)92116-8

A. Thrasher, M. Chetty, C. M. Casimir, and A. W. Segal, Restoration of superoxide generation to a chronic granulomatous disease-derived B-cell line by retrovirus mediated gene transfer, Blood, vol.80, issue.5, pp.1125-1129, 1992.

I. P. Thomsen, M. A. Smith, S. M. Holland, and C. B. Creech, A comprehensive approach to the management of children and adults with chronic granulomatous disease, The Journal of Allergy and Clinical Immunology: In Practice, vol.4, issue.6, pp.1082-1088, 2016.

I. Thomsen, D. E. Dulek, C. B. Creech, T. B. Graham, and J. V. Williams, Chronic granulomatous disease masquerading as Behcet disease: a case report and review of the literature, The Pediatric Infectious Disease Journal, vol.31, issue.5, pp.529-531, 2012.

S. Tsiodras, H. S. Gold, G. Sakoulas, G. M. Eliopoulos, C. Wennersten et al., Linezolid resistance in a clinical isolate of Staphylococcus aureus, Lancet, vol.358, issue.9277, pp.207-208, 2001.

, UMVF Aspergilloses et autres champignons filamenteux opportunistes-Association Française des Enseignants de Parasitologie et Mycologie (ANOFEL), p.2014

G. Uzel, J. S. Orange, N. Poliak, B. E. Marciano, T. Heller et al., Complications of tumor necrosis factor-alpha blockade in chronic granulomatous disease-related colitis, Clinical Infectious Diseases, vol.51, issue.12, pp.1429-1434, 2010.

F. Vandenesch, M. Bes, and E. J. Staphylococcus, , vol.2, pp.677-698, 1994.

F. Vandenesch, S. J. Eykyn, and E. , Infections caused by newly-described species of coagulase-negative staphylococci, Reviews in Medical Microbiology, vol.6, pp.94-100, 1995.
DOI : 10.1097/00013542-199504000-00002

J. Verhoef and E. Mattsson, The role of cytokines in Gram-positive bacterial shock, Trends in Microbiology, vol.3, issue.4, pp.136-140, 1995.

P. V. Vignais, The superoxide-generating NADPH oxidase: structural aspects and activation mechanism, Cellular and Molecular Life Sciences, vol.59, issue.9, pp.1428-1459, 2002.
DOI : 10.1007/s00018-002-8520-9

B. D. Volpp, W. M. Nauseef, J. E. Donelson, D. R. Moser, and R. A. Clark, Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase, Proceedings in the National Academy of Sciences of the, vol.86, pp.7195-7199, 1989.

D. Van-der-waaij, J. M. Berghuis, and J. E. Lekkerkerk, Colonization resistance of the digestive tract of mice during systemic antibiotic treatment, The Journal of Hygiene, vol.70, issue.4, pp.605-610, 1972.

M. M. Walther, H. Malech, A. Berman, P. Choyke, D. J. Venzon et al., The urological manifestations of chronic granulomatous disease, Journal of Urology, vol.147, issue.5, pp.1314-1318, 1992.

T. J. Walsh, I. Lutsar, T. Driscoll, B. Dupont, M. Roden et al., Voriconazole in the treatment of aspergillosis, scedosporiosis and other invasive fungal infections in children, The Pediatric Infectious Disease Journal, vol.21, issue.3, pp.240-248, 2002.

R. S. Weening, D. Boer, M. Kuijpers, T. W. Neefjes, V. M. Hack et al., Point mutations in the promoter region of the CYBB gene leading to mild chronic granulomatous disease, Clinical and Experimental Immunology, vol.122, issue.3, pp.410-417, 2000.

R. S. Weening, P. Kabel, P. Pijman, and D. Roos, Continuous therapy with sulfamethoxazole-trimethoprim in patients with chronic granulomatous disease, Journal of Pediatrics, vol.103, issue.1, pp.127-130, 1983.

R. S. Weening, G. Leitz, and R. A. Seger, Recombinant human interferon-gamma in patients with chronic granulomatous disease. European follow up study, European Journal of Pediatrics, vol.154, issue.4, pp.295-298, 1995.

S. L. Werlin, M. J. Chusid, J. Caya, and H. W. Oechler, Colitis in chronic granulomatous disease, Gastroenterology, vol.82, issue.2, pp.328-331, 1982.

D. A. Williams, W. Tao, F. Yang, C. Kim, Y. Gu et al., Dominant negative mutation of the hematopoieticspecific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency, Blood, vol.96, issue.5, pp.1646-1654, 2000.

D. B. Windhorst and R. A. Good, Dermatologic manifestations of fatal granulomatous disease of childhood, Archives of Dermatology, vol.103, issue.4, pp.351-357, 1971.

J. A. Winkelstein, M. C. Marino, J. Jr, R. B. Boyle, J. Curnutte et al., Report on a national registry of 368 patients, Medicine (Baltimore), vol.79, issue.3, pp.155-169, 2000.

B. Wolach, R. Gavrieli, M. De-boer, G. Gottesman, J. Ben-ari et al., Chronic granulomatous disease in Israel: clinical, functional and molecular studies of 38 patients, Clinical Immunology, vol.129, issue.1, pp.103-114, 2008.

B. Wolach, Y. Scharf, R. Gavrieli, M. De-boer, and D. Roos, Unusual late presentation of X-linked chronic granulomatous disease in an adult female with a somatic mosaic for a novel mutation in CYBB, Blood, vol.105, issue.1, pp.61-66, 2005.

R. C. Woodman, R. W. Erickson, R. J. Jaffe, H. S. Curnutte, and J. T. , Prolonged recombinant interferon-gamma therapy in chronic granulomatous disease: evidence against enhanced neutrophil oxidase activity, Blood, vol.79, issue.6, pp.1558-1562, 1992.

Y. C. Wu, Y. F. Huang, C. H. Lin, and C. C. Shieh, Detection of defective granulocyte function with flow cytometry in newborn infants, Immunology and Infection, vol.38, issue.1, pp.17-24, 2005.

M. A. Yamazaki-nakashimada, E. R. Stiehm, D. Pietropaolo-cienfuegos, V. Hernandez-bautista, and F. Espinosa-rosales, Corticosteroid therapy for refractory infections in chronic granulomatous disease: case reports and review of the literature, Asthma & Immunology, vol.97, issue.2, pp.257-261, 2006.

D. Zanditenas, H. Hagege, I. Rosa, P. Cattan, S. Ratel-saby et al., Inflammatory colitis and chronic granulomatous disease, a steroid-dependent case report, Gastroentérologie Clinique et Biologique, vol.28, issue.4, pp.398-401, 2004.

S. Zhan, N. Vaquez, F. B. Wientjes, M. L. Budarf, E. Schrock et al., Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex, Blood, vol.88, issue.7, pp.2714-2721, 1996.

M. Zhou, Z. Diwu, N. Panchuk-voloshina, and R. P. Haugland, A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of NADPH oxidase and other oxidases, Analytical Biochemistry, vol.253, issue.2, pp.162-168, 1997.