D. Abrams, C. A. Brodie, and D. , Extracorporeal membrane oxygenation in cardiopulmonary disease in adults, Journal of the American College of Cardiology, vol.63, pp.2769-78, 2014.

A. Combes, D. Brodie, Y. S. Chen, F. E. Henriques, J. Hodgson et al.,

K. Maekawa, T. Muller, S. Nuding, D. M. Ouweneel, A. Roch et al., The ICM research agenda on extracorporeal life support, Intensive care medicine, vol.43, pp.1306-1318, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01677426

P. Opfermann, M. Bevilacqua, A. Felli, M. Mouhieddine, T. Bachleda et al., Prognostic Impact of Persistent Thrombocytopenia During Extracorporeal Membrane Oxygenation: A Retrospective Analysis of Prospectively Collected Data From a Cohort of Patients With Left Ventricular Dysfunction After Cardiac Surgery, Critical care medicine, vol.44, pp.1208-1218, 2016.

J. E. Millar, J. P. Fanning, C. I. Mcdonald, D. F. Mcauley, and J. F. Fraser, The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology, Critical care, vol.20, p.387, 2016.

D. A. Murphy, L. E. Hockings, R. K. Andrews, C. Aubron, E. E. Gardiner et al.,

A. K. , Extracorporeal membrane oxygenation-hemostatic complications, Transfusion medicine reviews, vol.29, pp.90-101, 2015.

T. L. Bauer, G. Arepally, B. A. Konkle, B. Mestichelli, S. S. Shapiro et al.,

J. Amiral, W. W. Hauck, E. Rn, and J. D. Mannion, Prevalence of heparin-associated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery, Circulation, vol.95, pp.1242-1248, 1997.

C. Pouplard, M. A. May, S. Iochmann, J. Amiral, A. M. Vissac et al.,

, Antibodies to platelet factor 4-heparin after cardiopulmonary bypass in patients anticoagulated with unfractionated heparin or a low-molecular-weight heparin : clinical implications for heparin-induced thrombocytopenia, Circulation, vol.99, pp.2530-2536, 1999.

S. Selleng, B. Malowsky, U. Strobel, A. Wessel, T. Ittermann et al.,

A. Greinacher, Early-onset and persisting thrombocytopenia in post-cardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive, Journal of thrombosis and haemostasis : JTH, vol.8, pp.30-36, 2010.

Y. Sakr, What's new about heparin-induced thrombocytopenia type II, Intensive care medicine, vol.41, pp.1824-1831, 2015.

D. Glick, A. L. Dzierba, D. Abrams, J. Muir, A. Eisenberger et al.,

M. Bacchetta and D. Brodie, Clinically suspected heparin-induced thrombocytopenia during extracorporeal membrane oxygenation, Journal of critical care, vol.30, pp.1190-1194, 2015.

M. Sokolovic, A. K. Pratt, V. Vukicevic, M. Sarumi, J. Ls et al., Platelet Count Trends and Prevalence of Heparin-Induced Thrombocytopenia in a Cohort of Extracorporeal Membrane Oxygenator Patients, Critical care medicine, vol.44, pp.1031-1037, 2016.

A. Cuker and D. B. Cines, How I treat heparin-induced thrombocytopenia, Blood, vol.119, pp.2209-2227, 2012.

G. K. Lo, D. Juhl, T. E. Warkentin, C. S. Sigouin, P. Eichler et al., Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings, Journal of thrombosis and haemostasis : JTH, vol.4, pp.759-65, 2006.

J. Marler, J. Unzaga, S. Stelts, and C. S. Oliphant, Consequences of treating false positive heparin-induced thrombocytopenia, Journal of thrombosis and thrombolysis, vol.40, pp.512-516, 2015.

C. Aubron, A. C. Cheng, D. Pilcher, T. Leong, G. Magrin et al.,

V. Pellegrino, Factors associated with outcomes of patients on extracorporeal membrane oxygenation support: a 5-year cohort study, Critical care, vol.17, p.73, 2013.

A. Zangrillo, G. Landoni, G. Biondi-zoccai, M. Greco, T. Greco et al.,

M. , P. A. Pappalardo, and F. , A meta-analysis of complications and mortality of extracorporeal membrane oxygenation. Critical care and resuscitation : journal of the Australasian Academy of, Critical Care Medicine, vol.15, pp.172-180, 2013.

M. Schmidt, A. Burrell, L. Roberts, M. Bailey, J. Sheldrake et al.,

C. , C. D. Thiagarajan, R. R. Brodie, D. Pellegrino, V. Pilcher et al., Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score, European heart journal, vol.36, pp.2246-56, 2015.

M. Smith, A. Vukomanovic, D. Brodie, R. Thiagarajan, P. Rycus et al., Duration of veno-arterial extracorporeal life support (VA ECMO) and outcome: an analysis of the

, Extracorporeal Life Support Organization (ELSO) registry, Critical care

J. E. Millar, J. P. Fanning, C. I. Mcdonald, D. F. Mcauley, and J. F. Fraser, The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology, Critical Care, vol.20, p.387, 2016.

A. M. Capitanio, S. Niewiarowski, B. Rucinski, G. P. Tuszynski, and C. S. Cierniewski,

D. Hershock and E. Kornecki, Interaction of platelet factor 4 with human platelets, Biochimica et Biophysica Acta, vol.839, pp.161-173, 1985.

, Recherche d'anticorps potentiellement responsables d'une thrombopénie induite par l'héparine, HAS, 2005.

T. E. Warkentin, Heparin-induced thrombocytopenia: pathogenesis and management, British Journal of Haematology, vol.121, pp.535-555, 2003.

J. R. Bartholomew, S. M. Begelman, and A. Almahameed, Heparin-induced thrombocytopenia: principles for early recognition and management, Cleveland Clinic Journal of Medicine, vol.72, pp.31-36, 2005.

A. Greinacher, I. Michels, and C. Mueller-eckhardt, Heparin-associated thrombocytopenia: the antibody is not heparin specific, Thrombosis and Haemostasis, vol.67, pp.545-549, 1992.

J. Amiral, F. Bridey, M. Wolf, C. Boyer-neumann, E. Fressinaud et al.,

E. Debayle, M. Dreyfus, and D. Meyer, Antibodies to macromolecular platelet factor 4heparin complexes in heparin-induced thrombocytopenia: a study of 44 cases, Thrombosis and Haemostasis, vol.73, pp.21-28, 1995.

S. Ahmad, B. Untch, S. Haas, D. A. Hoppensteadt, F. Misselwitz et al., Fareed J, 2004.

, immunoglobulin subtypes in patients treated with clivarin and heparin: implications in the HIT pathogenesis, Molecular and Cellular Biochemistry, vol.258, pp.163-170

T. E. Warkentin, J. A. Sheppard, J. C. Moore, K. M. Moore, and C. S. Sigouin, , 2005.

, Laboratory testing for the antibodies that cause heparin-induced thrombocytopenia: how much class do we need?, The Journal of Laboratory and clinical Medicine, vol.146, pp.341-346

A. Greinacher, S. Alban, O. , M. A. Weitschies, W. Warkentin et al., , 2008.

, Heparin-induced thrombocytopenia: a stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings, Thrombosis Research, vol.122, pp.211-220

C. Pouplard, S. Iochmann, R. B. Herault, O. Colombat, P. Amiral et al., Induction of monocyte tissue factor expression by antibodies to heparin-platelet factor 4 complexes developed in heparin-induced thrombocytopenia, Blood, vol.97, pp.3300-3302, 2001.

S. T. Bebawy, J. Gorka, T. M. Hyers, and R. O. Webster, In vitro effects of platelet factor 4 on normal human neutrophil functions, Journal of Leukocyte Biology, vol.39, pp.423-434, 1986.

A. Cuker, Clinical and laboratory diagnosis of heparin-induced thrombocytopenia: an integrated approach, Seminars in Thrombosis and Hemostasis, vol.40, pp.106-114, 2014.

L. A. Linkins, A. L. Dans, L. K. Moores, R. Bona, B. L. Davidson et al., Treatment and prevention of heparin, 2012.

, American College of Chest Physicians Evidence-Based Clinical Practice Guidelines, Antithrombotic Therapy and Prevention of Thrombosis, vol.141, pp.495-530

G. K. Lo, D. Juhl, T. E. Warkentin, C. S. Sigouin, P. Eichler et al., , 2006.

, Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings, Journal of Thrombosis and Haemostasis : JTH, vol.4, pp.759-765

T. E. Warkentin, J. A. Sheppard, P. Horsewood, P. J. Simpson, J. C. Moore et al., Impact of the patient population on the risk for heparin-induced thrombocytopenia, Blood, vol.96, pp.1703-1708, 2000.

N. Lubenow, P. Hinz, S. Thomaschewski, T. Lietz, M. Vogler et al.,

M. Nauck, S. Schellong, K. Wander, G. Engel, A. Ekkernkamp et al., The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia, Blood, vol.115, pp.1797-1803, 2010.

T. E. Warkentin and A. Greinacher, Heparin-induced thrombocytopenia and cardiac surgery, The Annals of Thoracic Surgery, vol.76, pp.638-648, 2003.

D. Juhl, P. Eichler, N. Lubenow, U. Strobel, A. Wessel et al., Incidence and clinical significance of anti-PF4/heparin antibodies of the IgG, IgM, and IgA class in 755 consecutive patient samples referred for diagnostic testing for heparin-induced thrombocytopenia, European Journal of Haematology, vol.76, pp.420-426, 2006.

J. L. Francis, A critical evaluation of assays for detecting antibodies to the heparin-PF4 complex, Seminars in Thrombosis and Hemostasis, vol.30, pp.359-368, 2004.

M. Nagler and T. Bakchoul, Clinical and laboratory tests for the diagnosis of heparin-induced thrombocytopenia, Thrombosis and Haemostasis, vol.116, pp.823-834, 2016.

T. E. Warkentin, New approaches to the diagnosis of heparin-induced thrombocytopenia, Chest, vol.127, pp.35-45, 2005.

M. A. Crowther, D. J. Cook, M. O. Meade, L. E. Griffith, G. H. Guyatt et al.,

W. H. Geerts and T. E. Warkentin, Thrombocytopenia in medical-surgical critically ill patients: prevalence, incidence, and risk factors, Journal of Critical Care, vol.20, pp.348-353, 2005.

T. Thiele, K. Selleng, S. Selleng, A. Greinacher, and T. Bakchoul, , 2013.

, Thrombocytopenia in the intensive care unit-diagnostic approach and management, Seminars in Hematology, vol.50, pp.239-250

D. R. Williamson, M. Albert, D. Heels-ansdell, D. M. Arnold, F. Lauzier et al.,

M. Crowther, T. E. Warkentin, P. Dodek, J. Cade, O. Lesur et al.,

S. Langevin, A. Freitag, J. Muscedere, J. O. Friedrich, W. Geerts et al., Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes, Chest, vol.144, pp.1207-1215, 2013.

D. Abrams, M. R. Baldwin, M. Champion, C. Agerstrand, A. Eisenberger et al.,

D. Brodie, Thrombocytopenia and extracorporeal membrane oxygenation in adults with acute respiratory failure: a cohort study, Intensive Care Medicine, vol.42, pp.844-852, 2016.

P. Opfermann, M. Bevilacqua, A. Felli, M. Mouhieddine, T. Bachleda et al.,

M. Hiesmayr, A. Zuckermann, M. Dworschak, and B. Steinlechner, Prognostic Impact of Persistent Thrombocytopenia During Extracorporeal Membrane Oxygenation: A Retrospective Analysis of Prospectively Collected Data From a Cohort of Patients With Left Ventricular Dysfunction After Cardiac Surgery, Critical Care Medicine, vol.44, pp.1208-1218, 2016.

R. L. Levine, M. J. Hursting, and D. Mccollum, Argatroban therapy in heparininduced thrombocytopenia with hepatic dysfunction, Chest, vol.129, pp.1167-1175, 2006.

R. W. Yeh and I. K. Jang, Argatroban: update, American Heart Journal, vol.151, pp.1131-1138, 2006.

A. Assmann, U. Boeken, P. Feindt, P. Schurr, P. Akhyari et al., , 2010.

, Heparin-induced thrombocytopenia type II after cardiac surgery: predictors and outcome, The Thoracic and Cardiovascular Surgeon, vol.58, pp.463-467

S. Schenk, A. El-banayosy, W. Prohaska, L. Arusoglu, M. Morshuis et al.,

W. Eiserfunke, L. Kizner, E. Murray, P. Eichler, R. Koerfer et al., Heparininduced thrombocytopenia in patients receiving mechanical circulatory support, The Journal of Thoracic and Cardiovascular Surgery, vol.131, pp.1373-1381, 1374.

S. Schenk, A. El-banayosy, M. Morshuis, L. Arusoglu, P. Eichler et al.,

G. Tenderich, R. Koerfer, A. Greinacher, and W. Prohaska, IgG classification of anti, 2007.

, PF4/heparin antibodies to identify patients with heparin-induced thrombocytopenia during mechanical circulatory support, Journal of Thrombosis and Haemostasis : JTH, vol.5, pp.235-241

D. Glick, A. L. Dzierba, D. Abrams, J. Muir, A. Eisenberger et al.,

C. Agerstrand, M. Bacchetta, and D. Brodie, Clinically suspected heparin-induced thrombocytopenia during extracorporeal membrane oxygenation, Journal of Critical Care, vol.30, pp.1190-1194, 2015.

M. Sokolovic, A. K. Pratt, V. Vukicevic, M. Sarumi, L. S. Johnson et al., , 2016.

, Platelet Count Trends and Prevalence of Heparin-Induced Thrombocytopenia in a Cohort of Extracorporeal Membrane Oxygenator Patients, Critical Care Medicine, vol.44, pp.1031-1037

M. Schmidt, A. Burrell, L. Roberts, M. Bailey, J. Sheldrake et al.,

C. Scheinkestel, D. J. Cooper, R. R. Thiagarajan, D. Brodie, V. Pellegrino et al., Predicting survival after ECMO for refractory cardiogenic shock: the survival after venoarterial-ECMO (SAVE)-score, European Heart Journal, vol.36, pp.2246-2256, 2015.

J. Marler, J. Unzaga, S. Stelts, and C. S. Oliphant, Consequences of treating false positive heparin-induced thrombocytopenia, Journal of Thrombosis and Thrombolysis, vol.40, pp.512-514, 2015.

S. Selleng, B. Malowsky, U. Strobel, A. Wessel, T. Ittermann et al.,

T. E. and G. A. , Early-onset and persisting thrombocytopenia in post-cardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive, Journal of Thrombosis and Haemostasis : JTH, vol.8, pp.30-36, 2010.

C. Pouplard, M. A. May, S. Iochmann, J. Amiral, A. M. Vissac et al., Antibodies to platelet factor 4-heparin after cardiopulmonary bypass in patients anticoagulated with unfractionated heparin or a low-molecular-weight heparin : clinical implications for heparin-induced thrombocytopenia, Circulation, vol.99, pp.2530-2536, 1999.

A. Kallam, A. Singla, and P. Silberstein, Proton pump induced thrombocytopenia: A case report and review of literature, Platelets, vol.26, pp.598-601, 2015.

A. Greinacher, B. Farner, H. Kroll, T. Kohlmann, T. E. Warkentin et al., analysis of 408 patients, Thrombosis and Haemostasis, vol.94, pp.132-135, 2005.

T. L. Bauer, G. Arepally, B. A. Konkle, B. Mestichelli, S. S. Shapiro et al.,

S. Mcnulty, J. Amiral, W. W. Hauck, R. N. Edie, and J. D. Mannion, Prevalence of heparinassociated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery, Circulation, vol.95, pp.1242-1246, 1997.

J. Bain, A. H. Flannery, J. Flynn, and W. Dager, Heparin induced thrombocytopenia with mechanical circulatory support devices: review of the literature and management considerations, Journal of Thrombosis and Thrombolysis, vol.44, pp.76-87, 2017.