L. .. Des-tableaux,

B. .. ,

. , Liste des tableaux Tableau 1: Application de l'apithérapie dans les différents domaines de la médecine buccodentaire

Y. Donadieu, Introduction à l'apithérapie, 2003.

. Disponible,

A. Becker,

. Disponible,

C. Viel and J. Doré, Histoire et emplois du miel, de l'hydromel et des produits de la ruche, Rev Hist Pharm, vol.91, issue.337, pp.7-20, 2003.
DOI : 10.3406/pharm.2003.5474

URL : https://hal.archives-ouvertes.fr/hal-00013132

, Dépenses de santé?Tableaux de l'Économie Française | Insee, 2016.

. Disponible,

L. Miel, Information générale, Morphologie. Disponible sur

. Api-douceur.-c'est-comment-dans-la-ruche, , 2012.

. Disponible,

. Legifrance, Décret n° 2003-587 du 30 juin 2003 Décret n° 2003-587 du 30 juin 2003 pris pour l'application de l'article L. 214-1 du code de la consommation en ce qui concerne le miel, 2003.

. Disponible,

J. W. White, Doner LW. Honey Composition and Properties, 1980.

. Disponible,

P. C. Molan, The antibacterial activity of honey: 1. The nature of the antibacterial activity, 2006.

M. Gharbi, Les produits de la ruche : origines, fonctions naturelles, composition, propriétés thérapeutiques, apithérapie et perspectives d'emploi en médecine vétérinaire, 2011.

, Disponible sur: www2.vetagrosup, p.247

A. Ahuja and V. A. , Apitherapy-A sweet approach to dental diseases-Part I : Honey, J Adv Dent Res, vol.1, 2010.

S. Bogdanov and P. Blumer, Propriétés antibiotiques naturelles du miel, 2001.

. Disponible,

D. Lechaux, Le miel et la cicatrisation des plaies, 2017.

. Disponible,

A. Syeda-arshiya, Use of apithérapy as a novel practice in the management of oral diseases : a review of literature, vol.26, 2013.

P. Kwakman, A. A. Velde, . Boer-l-de, D. Speijer, C. Vandenbroucke-grauls et al., How honey kills bacteria, FASEB J. 7 janv, vol.24, issue.7, pp.2576-82, 2010.

, Apithérapie : les produits de la ruche pour le bien-être et la santé, Abeilles et fleurs, p.13, 2012.

P. Kwakman, A. A. Velde, L. De-boer, C. Vandenbroucke-grauls, and S. Zaat, Two Major Medicinal Honeys Have Different Mechanisms of Bactericidal Activity, PLoS ONE. 4 mars, vol.6, issue.3, p.17709, 2011.

C. Badet and F. Quero, The in vitro effect of manuka honeys on growth and adherence of oral bacteria, Anaerobe. févr, vol.17, issue.1, pp.19-22, 2011.

P. A. Nayak, U. A. Nayak, and R. Mythili, Effect of Manuka honey, chlorhexidine gluconate and xylitol on the clinical levels of dental plaque. Contemp Clin Dent, vol.1, pp.214-221, 2010.

H. English, A. Pack, and P. C. Molan, The effects of manuka honey on plaque and gingivitis: a pilot study, J Int Acad Periodontol. avr, vol.6, issue.2, pp.63-70, 2004.

S. Rupesh, J. J. Winnier, U. A. Nayak, A. P. Rao, N. V. Reddy et al., Evaluation of the effects of manuka honey on salivary levels of mutans streptococci in children: a pilot study, J Indian Soc Pedod Prev Dent. sept, vol.32, issue.3, pp.212-221, 2014.

M. C. Marcucci, Propolis: chemical composition, biological properties and therapeutic activity, Apidologie, vol.26, issue.2, pp.83-99, 1995.
URL : https://hal.archives-ouvertes.fr/hal-00891249

T. Farooqui and A. , Molecular Mechanism Underlying the Therapeutic Activities of Propolis: A Critical Review, Curr Nutr Amp Food Sci, vol.6, issue.3, pp.186-99, 2010.

F. Scazzocchio, D. Auria, F. D. Alessandrini, D. Pantanella, and F. , Multifactorial aspects of antimicrobial activity of propolis, Microbiol Res, vol.17, issue.4, pp.327-360, 2006.

J. B. Daleprane, D. Abdalla, I. Saes, J. B. Daleprane, D. Abdalla et al., Emerging Roles of Propolis: Antioxidant, Cardioprotective, and Antiangiogenic Actions, Emerging Roles of Propolis: Antioxidant, Cardioprotective, and Antiangiogenic Actions. Evid-Based Complement Altern Med Evid-Based, Complement Altern Med. 8 avr, p.175135, 2013.

A. Ramos and J. L. Miranda, Propolis: a review of its anti-inflammatory and healing actions, J Venom Anim Toxins Trop Dis, vol.13, issue.4, pp.697-710, 2007.

. Almeida-ec-de and H. Menezes, Anti-inflammatory activity of propolis extracts: a review, J Venom Anim Toxins, vol.8, issue.2, pp.191-212, 2002.

C. Chuu, H. Lin, M. F. Ciaccio, J. M. Kokontis, R. J. Hause et al., Caffeic acid phenethyl ester suppresses the proliferation of human prostate cancer cells through inhibition of p70S6K and Akt signaling networks, Cancer Prev Res Phila Pa. mai, vol.5, issue.5, pp.788-97, 2012.

C. O. Omene, J. Wu, and K. Frenkel, Caffeic Acid Phenethyl Ester (CAPE) derived from propolis, a honeybee product, inhibits growth of breast cancer stem cells, Invest New Drugs. août, vol.30, issue.4, pp.1279-88, 2012.

M. Demestre, S. M. Messerli, N. Celli, M. Shahhossini, L. Kluwe et al., CAPE (caffeic acid phenethyl ester)-based propolis extract (Bio 30) suppresses the growth of human neurofibromatosis (NF) tumor xenografts in mice, Phytother Res PTR. févr, vol.23, issue.2, pp.226-256, 2009.

N. Cardinault and M. , La propolis : origine, composition et propriétés, Phytotherapie, vol.10, issue.5, pp.298-304, 2012.
DOI : 10.1007/s10298-012-0733-y

, Organisation Mondiale de la Santé | Santé bucco-dentaire: aide-mémoire n°318, 2012.

. Disponible,

, Haute Autorité de Santé-Stratégies de prévention de la carie dentaire

. Disponible,

G. G. Nicolas and M. C. Lavoie, Streptococcus mutans et les streptocoques buccaux dans la plaque dentaire, Can J Microbiol. décembre, vol.57, issue.1, pp.1-20, 2010.

W. Krzy?ciak, A. Jurczak, D. Ko?cielniak, B. Bystrowska, and A. Skalniak, The virulence of Streptococcus mutans and the ability to form biofilms, Eur J Clin Microbiol Infect Dis, vol.33, issue.4, pp.499-515, 2014.

S. Libério, A. Luís, M. J. Pereira, R. Araújo, F. Dutra et al., The potential use of propolis as a cariostatic agent and its actions on mutans group streptococci, 2009.

. Disponible,

T. M. Karpi?ski and A. K. Szkaradkiewicz, Chlorhexidine-pharmaco-biological activity and application, Eur Rev Med Pharmacol Sci. avr, vol.19, issue.7, pp.1321-1327, 2015.

C. A. Gürgan, E. Zaim, I. Bakirsoy, and E. Soykan, Short-term side effects of 0.2% alcohol-free chlorhexidine mouthrinse used as an adjunct to non-surgical periodontal treatment: a double-blind clinical study, J Periodontol. mars, vol.77, issue.3, pp.370-84, 2006.

S. Duarte, P. L. Rosalen, M. F. Hayacibara, J. A. Cury, W. H. Bowen et al., The influence of a novel propolis on mutans streptococci biofilms and caries development in rats, Arch Oral Biol. janv, vol.51, issue.1, pp.15-22, 2006.

S. M. Alencar, T. Oldoni, M. L. Castro, I. Cabral, C. M. Costa-neto et al., Chemical composition and biological activity of a new type of Brazilian propolis: red propolis, J Ethnopharmacol. 5 sept, vol.113, issue.2, pp.278-83, 2007.

A. Uzel, K. Sorkun, Ö. Önça?, D. Ço?ulu, Ö. Gençay et al., Chemical compositions and antimicrobial activities of four different Anatolian propolis samples, Microbiol Res. avril, vol.160, issue.2, pp.189-95, 2005.

A. Sawaya, K. S. Souza, M. C. Marcucci, I. Cunha, and M. T. Shimizu, Analysis of the composition of Brazilian propolis extracts by chromatography and evaluation of their in vitro activity against gram-positive bacteria, Braz J Microbiol. juin, vol.35, issue.1-2, pp.104-113, 2004.

H. Koo, B. P. Gomes, P. L. Rosalen, G. M. Ambrosano, Y. K. Park et al., In vitro antimicrobial activity of propolis and Arnica montana against oral pathogens, Arch Oral Biol. févr, vol.45, issue.2, pp.141-149, 2000.

Y. K. Park, M. H. Koo, J. A. Abreu, M. Ikegaki, J. A. Cury et al., Antimicrobial activity of propolis on oral microorganisms, Curr Microbiol. janv, vol.36, issue.1, pp.24-32, 1998.

J. J. Veloz, N. Saavedra, M. Alvear, T. Zambrano, L. Barrientos et al., PolyphenolRich Extract from Propolis Reduces the Expression and Activity of Streptococcus mutans Glucosyltransferases at Subinhibitory Concentrations, BioMed Res Int, 2016.

S. Duarte, H. Koo, W. H. Bowen, M. F. Hayacibara, J. A. Cury et al., Effect of a novel type of propolis and its chemical fractions on glucosyltransferases and on growth and adherence of mutans streptococci, Biol Pharm Bull. avr, vol.26, issue.4, pp.527-558, 2003.

K. Ikeno, T. Ikeno, and C. Miyazawa, Effects of propolis on dental caries in rats, Caries Res, vol.25, issue.5, pp.347-51, 1991.

D. Steinberg, G. Kaine, and I. Gedalia, Antibacterial effect of propolis and honey on oral bacteria, Am J Dent. déc, vol.9, issue.6, pp.236-245, 1996.

C. Duailibe-sa-de, A. G. Gonçalves, F. Ahid, O. Effect, and . Vivo, J Appl Oral Sci, vol.15, issue.5, pp.420-423, 2007.

. Ladepeche, Congrès des apiculteurs : plus de miel et moins de caries, 2016.

. Disponible,

A. Atwa, R. Y. Abushahba, M. Mostafa, and M. I. Hashem, Effect of honey in preventing gingivitis and dental caries in patients undergoing orthodontic treatment, Saudi Dent J. juill, vol.26, issue.3, pp.108-122, 2014.

P. Abhishek, M. Thomas, M. Kundabala, and M. Mandakini, Propolis and Its Potential Uses in Oral Health, 2010.

Z. Ahangari, M. Naseri, M. Jalili, Y. Mansouri, F. Mashhadiabbas et al., Effect of propolis on dentin regeneration and the potential role of dental pulp stem cell in Guinea pigs, Cell J, vol.13, issue.4, pp.223-231, 2012.

, Le Conseil consultatif canadien sur l'hypersensibilité dentinaire. Recommandations consensuelles sur le diagnostic et le traitement de l'hypersensibilité dentinaire

K. Almas, A. Dahlan, and A. Mahmoud, Journal of International Oral Health, vol.8, pp.646-649, 2016.

P. Mehta, N. Vimala, and L. Mandke, An insight into dentin desensitizing agents-In vivo study, Indian J Dent Res, vol.24, issue.5, p.571, 2013.

S. Sh-de, C. De, C. Fn, J. A. Marsicano, M. Mc et al., Effect of propolis gel on the in vitro reduction of dentin permeability, J Appl Oral Sci, vol.19, issue.4, pp.318-341, 2011.

B. Gomes, E. T. Pinheiro, C. R. Gadê-neto, E. Sousa, C. Ferraz et al., Microbiological examination of infected dental root canals, Oral Microbiol Immunol. avr, vol.19, issue.2, pp.71-77, 2004.

I. E. Karim, J. Kennedy, and D. Hussey, The antimicrobial effects of root canal irrigation and medication. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1 avr, vol.103, pp.560-569, 2007.

H. Al-qathami, A. , and E. , Comparison of sodium hypochlorite, propolis and saline, 2003.

. Disponible,

S. Mattigatti, P. Ratnakar, S. Moturi, S. Varma, and S. Rairam, Antimicrobial effect of conventional root canal medicaments vs propolis against Enterococcus faecalis, Staphylococcus aureus and Candida albicans, J Contemp Dent Pract. 1 mai, vol.13, issue.3, pp.305-314, 2012.

M. Jolly, N. Singh, M. Rathore, S. Tandon, and M. Banerjee, Propolis and commonly used intracanal irrigants: comparative evaluation of antimicrobial potential, J Clin Pediatr Dent, vol.37, issue.3, pp.243-252, 2013.

, Haute Autorité de Santé-Traitement endodontique

. Disponible,

J. O. Andreasen, B. Farik, and E. C. Munksgaard, Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture, Dent Traumatol Off Publ Int Assoc Dent Traumatol. juin, vol.18, issue.3, pp.134-141, 2002.

D. Kim and E. Kim, Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review-Part I. In vitro studies. Restor Dent Endod, vol.39, pp.241-52, 2014.

Z. Jahromi, M. Toubayani, H. Rezaei, and M. , Propolis: A New Alternative for Root Canal Disinfection, Iran Endod J, vol.7, issue.3, pp.127-160, 2012.

F. B. Silva, . Da, J. M. Almeida, . De, S. Sousa et al., Natural medicaments in endodontics-a comparative study of the anti-inflammatory action, Braz Oral Res. juin, vol.18, issue.2, pp.174-183, 2004.

H. Jansson, Studies on periodontitis and analyses of individuals at risk for periodontal diseases, Swed Dent J Suppl, issue.180, pp.5-49, 2006.

, Haute Autorité de Santé-Parodontopathies : diagnostic et traitements

. Disponible,

E. Gebara, L. A. Lima, and M. Mayer, Propolis antimicrobial activity against periodontopathic bacteria, Braz J Microbiol. déc, vol.33, issue.4, pp.365-374, 2002.

F. A. Santos, E. Bastos, M. Uzeda, M. Carvalho, L. M. Farias et al., Antibacterial activity of Brazilian propolis and fractions against oral anaerobic bacteria, J Ethnopharmacol. avril, vol.80, issue.1, pp.1-7, 2002.

P. C. Molan, Potential of honey in the treatment of wounds and burns, Am J Clin Dermatol, vol.2, issue.1, pp.13-22, 2001.

F. Özan, Z. Sümer, Z. A. Polat, K. Er, Ü. Özan et al., Effect of Mouthrinse Containing Propolis on Oral Microorganisms and Human Gingival Fibroblasts, Eur J Dent, vol.1, issue.4, pp.195-201, 2007.

V. Dodwad and B. J. Kukreja, Propolis mouthwash: A new beginning, J Indian Soc Periodontol, vol.15, issue.2, pp.121-126, 2011.

S. O. Akintoye and M. S. Greenberg, Recurrent Aphthous Stomatitis, Dent Clin North Am. avr, vol.58, issue.2, pp.281-97, 2014.

N. Samet, C. Laurent, S. M. Susarla, and N. Samet-rubinsteen, The effect of bee propolis on recurrent aphthous stomatitis: a pilot study, Clin Oral Investig. juin, vol.11, issue.2, pp.143-150, 2007.

V. R. Santos, F. Pimenta, M. Aguiar, .. V. Naves, M. D. Mesquita et al., Oral candidiasis treatment with Brazilian ethanol propolis extract, Phytother Res PTR. juill, vol.19, issue.7, pp.652-656, 2005.

R. Martins, E. Péreira, S. Lima, M. Senna, R. Mesquita et al., Effect of commercial ethanol propolis extract on the in vitro growth of Candida albicans collected from HIVseropositive and HIV-seronegative Brazilian patients with oral candidiasis, Journal of Oral Science, vol.44, issue.1, pp.41-49, 2002.

B. E. Mccartan and C. M. Healy, The reported prevalence of oral lichen planus: a review and critique, J Oral Pathol Med Off Publ Int Assoc Oral Pathol Am Acad Oral Pathol. sept, vol.37, issue.8, pp.447-53, 2008.

S. K. Jaganathan and M. Mandal, Antiproliferative Effects of Honey and of Its Polyphenols: A Review, BioMed Res Int. 19 juill, p.830616, 2009.

J. M. Alvarez-suarez, S. Tulipani, D. Díaz, Y. Estevez, S. Romandini et al., Antioxidant and antimicrobial capacity of several monofloral Cuban honeys and their correlation with color, polyphenol content and other chemical compounds, Food Chem Toxicol Int J Publ Br Ind Biol Res Assoc. sept, vol.48, issue.8-9, pp.2490-2499, 2010.

M. K. Tan, H. Adli, D. S. Tumiran, M. A. Abdulla, M. A. Yusoff et al., The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing. Evid Based, Complement Alternat Med. 28 mars, p.805932, 2012.

M. Sanatkhani, M. Mozafari, P. Amirchaghmaghi, M. , N. Fathi et al., Effect of Cedar Honey in the Treatment of Oral Lichen Planus, Iran J Otorhinolaryngol. juill, vol.26, issue.76, pp.151-61, 2014.

, Organisation Mondiale de la Santé | Herpès (virus de l'herpès)

L. A. Waggoner-fountain and L. B. Grossman, Herpes simplex virus, Pediatr Rev. mars, vol.25, issue.3, pp.86-93, 2004.

E. Frobert, S. Burrel, S. Ducastelle-lepretre, G. Billaud, F. Ader et al., Resistance of herpes simplex viruses to acyclovir: an update from a ten-year survey in France, Antiviral Res. nov, vol.111, pp.36-41, 2014.

A. Yildirim, G. G. Duran, N. Duran, K. Jenedi, B. S. Bolgul et al., Antiviral Activity of Hatay Propolis Against Replication of Herpes Simplex Virus Type 1 and Type 2, Med Sci Monit Int Med J Exp Clin Res. 9 févr, vol.22, pp.422-452, 2016.

N. B. Takaisi-kikuni and H. Schilcher, Electron Microscopic and Microcalorimetric Investigations of the Possible Mechanism of the Antibacterial Action of a Defined Propolis Provenance, Planta Med. juin, vol.60, issue.03, pp.222-229, 1994.

M. A. Hashemipour, Z. Tavakolineghad, S. Arabzadeh, Z. Iranmanesh, and S. Nassab, Antiviral Activities of Honey, Royal Jelly, and Acyclovir Against HSV-1. Wounds Compend Clin Res Pract. févr, vol.26, issue.2, pp.47-54, 2014.

H. Holzgreve,

, MMW Fortschr Med. 20 janv, vol.147, issue.3, p.18, 2005.

A. Ns, Topical honey application vs. acyclovir for the treatment of recurrent herpes simplex lesions, Med Sci Monit Int Med J Exp Clin Res. août, vol.10, issue.8, pp.94-98, 2004.

E. F. Elbagoury and N. A. Fayed, Application of « natural honey » after surgical removal of impacted lower third molar, Egypt Dent J. juill, vol.31, issue.3, pp.203-214, 1985.

E. F. Elbagoury and S. Rasmy, Antibacterial action of natural honey on anaerobic bacteroides, Egypt Dent J. janv, vol.39, issue.1, pp.381-387, 1993.

N. Soni, V. Singh, S. Mohammad, R. K. Singh, U. S. Pal et al., Effects of honey in the management of alveolar osteitis: A study, Natl J Maxillofac Surg, vol.7, issue.2, pp.136-183, 2016.

K. Souaga, A. Adou, D. Amantchi, and Y. Angoh, Le traitement des alvéolites en pratique odonto-stomatologique notre expérience

D. Passi, G. Singh, S. Dutta, S. Sharma, S. Mishra et al., RETRACTED ARTICLE: Honey Extract as Medicament for Treatment of Dry Socket: An Ancient Remedy Rediscovered-Case Series and Literature Review, J Maxillofac Oral Surg. 1 sept, vol.15, issue.3, pp.345-345, 2016.