,
, Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I), Br J Cancer, vol.102, issue.7, pp.1123-1131, 2010.
Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups, J Clin Oncol, vol.15, issue.5, pp.2040-2049, 1997. ,
Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study, J Clin Oncol, vol.14, issue.9, pp.2527-2566, 1996. ,
Long-Term Update of US GI Intergroup RTOG 98-11 Phase III Trial for Anal Carcinoma: Survival, Relapse, and Colostomy Failure With Concurrent Chemoradiation Involving Fluorouracil/Mitomycin Versus Fluorouracil/Cisplatin, J Clin Oncol, vol.30, issue.35, pp.4344-51, 2012. ,
,
, Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2$\times$ 2 factorial trial, Lancet Oncol, vol.14, issue.6, pp.516-540, 2013.
Predictors and Patterns of Recurrence After Definitive Chemoradiation for Anal Cancer, Int J Radiat Oncol, vol.68, issue.3, pp.794-800, 2007. ,
Squamous Cell Carcinoma of the Anal Canal: Patterns and Predictors of Failure and Implications for Intensity-Modulated Radiation Treatment Planning, Int J Radiat Oncol, vol.78, issue.4, pp.1064-72, 2010. ,
IMRT for locally advanced anal cancer: clinical experience of the Montpellier Cancer Center, Radiat Oncol, vol.7, issue.1, p.45, 2012. ,
French multicentre clinical evaluation of helical TomoTherapy® for anal cancer in a cohort of 64 consecutive patients, Radiat Oncol, vol.10, issue.1, 2015. ,
Organ-sparing Intensitymodulated Radiotherapy for Anal Cancer using the ACTII Schedule: A Comparison of Conventional and Intensity-modulated Radiotherapy Plans, Clin Oncol, vol.25, issue.3, pp.155-61, 2013. ,
RTOG 0529: A Phase 2 Evaluation of Dose-Painted Intensity Modulated Radiation Therapy in Combination With 5Fluorouracil and Mitomycin-C for the Reduction of Acute Morbidity in Carcinoma of the Anal Canal, Int J Radiat Oncol, vol.86, issue.1, pp.27-33, 2013. ,
Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: Toxicity and clinical outcome, Int J Radiat Oncol, vol.63, issue.2, pp.354-61, 2005. ,
Organ sparing by conformal avoidance intensity-modulated radiation therapy for anal cancer: Dosimetric evaluation of coverage of pelvis and inguinal/femoral nodes, Int J Radiat Oncol, vol.63, issue.1, pp.274-81, 2005. ,
Intensity-Modulated Radiation Therapy vs. 3D Conformal Radiation Therapy for Squamous Cell Carcinoma of the Anal Canal, Gastrointest Cancer Res, vol.6, pp.39-45, 2013. ,
Recurrences near base of skull after IMRT for head-and-neck cancer: implications for target delineation in high neck and for parotid gland sparing, Int J Radiat Oncol, vol.70, issue.3, pp.28-42, 2004. ,
Australasian Gastrointestinal Trials Group (AGITG) Contouring Atlas and Planning Guidelines for Intensity-Modulated Radiotherapy in Anal Cancer, Int J Radiat Oncol, vol.83, issue.5, pp.1455-62, 2012. ,
Elective Clinical Target Volumes for Conformal Therapy in Anorectal Cancer: A Radiation Therapy Oncology Group Consensus Panel Contouring Atlas, Int J Radiat Oncol, vol.74, issue.3, pp.824-854, 2009. ,
, Site Internat de radioanatomie et d'autoenseignement à la délinéation (SIRIADE). Paris: Afcor,SFRO,SFJRO, 2011.
Mitomycin, and Radiotherapy vs Fluorouracil, Cisplatin, and Radiotherapy for Carcinoma of the Anal Canal, JAMA, vol.299, issue.16, pp.1914-1935, 2008. ,
,
, Induction Chemotherapy and Dose Intensification of the Radiation Boost in Locally Advanced Anal Canal Carcinoma: Final Analysis of the Randomized UNICANCER ACCORD 03 Trial, J Clin Oncol, vol.30, issue.16, pp.1941-1949, 2012.
Tobacco smoking and risk of recurrence for squamous cell cancer of the anus, Cancer Detect Prev, vol.32, issue.2, pp.116-136, 2008. ,
Low-dose-rate interstitial brachytherapy boost for the treatment of anal canal cancers, Brachytherapy, vol.16, issue.1, pp.230-235, 2017. ,
High-Dose Split-Course Radiation Therapy for Anal Cancer: Outcome Analysis Regarding the Boost Strategy (CORS03 Study), Int J Radiat Oncol, vol.80, issue.3, pp.712-732, 2011. ,
,
Anal cancer incidence and survival: The Surveillance, Epidemiology, and End Results experience, Cancer, vol.101, issue.2, pp.281-289, 1973. ,
The epidemiology of anal cancer, Sex Health, vol.9, issue.6, p.504, 2012. ,
Cancer statistics, 2017. CA Cancer J Clin, 2017. ,
Trends of incidence and survival in squamous-cell carcinoma of the anal canal in France: a population-based study, Eur J Cancer Prev, vol.25, issue.3, pp.182-189, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01442356
International trends in anal cancer incidence rates, Int J Epidemiol, p.276, 2016. ,
Anal cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis ,
URL : https://hal.archives-ouvertes.fr/hal-01799935
, Radiother Oncol, vol.111, issue.3, pp.330-339, 2014.
Cancer du canal anal ,
, Cancer/Radiothérapie, vol.14, pp.120-126, 2010.
Épidémiologie du cancer de l'anus. Cancéro Dig, 2011. ,
World Health Organization, International Agency for Research on Cancer, Pathology and genetics of tumours of the digestive system. Lyon : Oxford: IARC Press ,
On the etiology of anal squamous carcinoma, Dan Med Bull, 2002. ,
Classification OMS 2010 des tumeurs digestives : la quatrième édition, Ann Pathol, vol.31, issue.5, pp.27-31, 2011. ,
Anal cancer and human papillomaviruses, Dis Colon Rectum, vol.32, issue.12, pp.1016-1038, 1989. ,
,
, Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer, N Engl J Med, vol.348, issue.6, pp.518-545, 2003.
Human papillomavirus genotype distribution in anal cancer in France: The EDiTH V study, Int J Cancer, vol.129, issue.2, pp.433-442, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00563122
Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. The Lancet, vol.370, pp.59-67, 2007. ,
Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer. Cancer, vol.101, pp.270-80, 2004. ,
Cigarette smoking and the risk of anogenital cancer, Am J Epidemiol, vol.135, issue.2, pp.180-189, 1992. ,
A systematic review of anal squamous cell carcinoma in inflammatory bowel disease, Surg Oncol, vol.22, issue.4, pp.230-237, 2013. ,
,
, Emission Tomography/Computed Tomography for Staging and Radiotherapy Planning in Patients With Anal Cancer, Int J Radiat Oncol, vol.81, issue.2, pp.445-51, 2011.
Anal carcinoma: FDG PET/CT in staging, response evaluation, and follow-up, Abdom Imaging, vol.38, issue.4, pp.728-763, 2013. ,
FDGPET/CT in the evaluation of anal carcinoma, Int J Radiat Oncol, vol.65, issue.3, pp.720-725, 2006. ,
Impact of FDG PET/CT in the staging and the follow-up of anal carcinoma, Int J Colorectal Dis, vol.26, issue.2, pp.201-211, 2011. ,
The impact of 18fluorodeoxyglucose positron emission tomography on the staging, management and outcome of anal cancer, Br J Cancer, vol.100, issue.5, pp.693-700, 2009. ,
,
, Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I), Br J Cancer, vol.102, issue.7, pp.1123-1131, 2010.
Predictors and Patterns of Recurrence After Definitive Chemoradiation for Anal Cancer, Int J Radiat Oncol, vol.68, issue.3, pp.794-800, 2007. ,
Squamous Cell Carcinoma of the Anal Canal: Patterns and Predictors of Failure and Implications for IntensityModulated Radiation Treatment Planning, Int J Radiat Oncol, vol.78, issue.4, pp.1064-72, 2010. ,
Squamous cell carcinoma of the anus at one hospital from 1948 to 1984, Br J Surg, vol.76, issue.8, pp.806-816, 1989. ,
Results and toxicity of the treatment of anal canal carcinoma by radiation therapy or radiation therapy and chemotherapy. Cancer, vol.54, pp.2062-2070, 1984. ,
A new approach to the management of epidermoid carcinoma of the anal canal. Cancer, vol.51, pp.1830-1837, 1983. ,
Squamous cell carcinoma of the anal canal: treatment by external beam irradiation, Radiother Oncol, vol.3, issue.2, pp.145-50, 1985. ,
Epidermoid carcinoma of the anal canal. Results of curative-intent radiation therapy in a series of 270 patients, Cancer, vol.73, issue.6, pp.1569-79, 1994. ,
,
, Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups, J Clin Oncol, vol.15, issue.5, pp.2040-2049, 1997.
Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study, J Clin Oncol, vol.14, issue.9, pp.2527-2566, 1996. ,
LongTerm Update of US GI Intergroup RTOG 98-11 Phase III Trial for Anal Carcinoma: Survival, Relapse, and Colostomy Failure With Concurrent Chemoradiation Involving Fluorouracil/Mitomycin Versus Fluorouracil/Cisplatin, J Clin Oncol, vol.30, issue.35, pp.4344-51, 2012. ,
,
, Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2$\times$ 2 factorial trial, Lancet Oncol, vol.14, issue.6, pp.516-540, 2013.
Induction Chemotherapy and Dose Intensification of the Radiation Boost in Locally Advanced Anal Canal Carcinoma: Final Analysis of the Randomized UNICANCER ACCORD 03 Trial, J Clin Oncol, vol.30, issue.16, pp.1941-1949, 2012. ,
,
, Treatment intensification by induction chemotherapy (ICT) and radiation dose escalation in locally advanced squamous cell anal canal carcinoma (LAAC): Definitive analysis of the intergroup ACCORD 03 trial, J Clin Oncol, vol.27, issue.15S, p.4033, 2009.
,
, Chemotherapy in the treatment of anal canal carcinoma. Dig Liver Dis, vol.44, pp.803-814, 2012.
Mitomycin, and Radiotherapy vs Fluorouracil, Cisplatin, and Radiotherapy for Carcinoma of the Anal Canal, JAMA, vol.299, issue.16, pp.1914-1935, 2008. ,
Chapitre 6 Cancer du canal anal, 2017. ,
, Anon. NCCN clinical practice guidelines (NCCN Guidelines®) in oncology. Anal carcinoma. Fort Washington, PA: National Comprehensive Cancer Network, 2014.
Australasian Gastrointestinal Trials Group (AGITG) Contouring Atlas and Planning Guidelines for IntensityModulated Radiotherapy in Anal Cancer, Int J Radiat Oncol, vol.83, issue.5, pp.1455-62, 2012. ,
Evaluation of Planned Treatment Breaks During Radiation Therapy for Anal Cancer: Update of RTOG 92-08, Int J Radiat Oncol, vol.72, issue.1, pp.114-122, 2008. ,
Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: Toxicity and clinical outcome, Int J Radiat Oncol, vol.63, issue.2, pp.354-61, 2005. ,
Organ sparing by conformal avoidance intensity-modulated radiation therapy for anal cancer: Dosimetric evaluation of coverage of pelvis and inguinal/femoral nodes, Int J Radiat Oncol, vol.63, issue.1, pp.274-81, 2005. ,
Optimal organ-sparing intensity-modulated radiation therapy (IMRT) regimen for the treatment of locally advanced anal canal carcinoma: a comparison of conventional and IMRT plans, Radiat Oncol, vol.2, issue.1, p.41, 2007. ,
RTOG 0529: A Phase 2 Evaluation of Dose-Painted Intensity Modulated Radiation Therapy in Combination With 5-Fluorouracil and Mitomycin-C for the Reduction of Acute Morbidity in Carcinoma of the Anal Canal, Int J Radiat Oncol, vol.86, issue.1, pp.27-33, 2013. ,
Elective Clinical Target Volumes for Conformal Therapy in Anorectal Cancer: A Radiation Therapy Oncology Group Consensus Panel Contouring Atlas, Int J Radiat Oncol, vol.74, issue.3, pp.824-854, 2006. ,
Radioth?rapie des cancers du canal anal. Cancer/Radioth?rapie, Site Internat de radioanatomie et d'autoenseignement à la délinéation (SIRIADE), vol.20, pp.183-191, 2011. ,
Patterns of localregional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer, Int J Radiat Oncol Biol Phys, vol.46, issue.5, pp.1117-1143, 2000. ,
Recurrences near base of skull after IMRT for head-and-neck cancer: implications for target delineation in high neck and for parotid gland sparing, Int J Radiat Oncol, vol.70, issue.3, pp.28-42, 2004. ,
IMRT for locally advanced anal cancer: clinical experience of the Montpellier Cancer Center, Radiat Oncol, vol.7, issue.1, p.45, 2012. ,
French multicentre clinical evaluation of helical TomoTherapy® for anal cancer in a cohort of 64 consecutive patients, Radiat Oncol, vol.10, issue.1, 2015. ,
Organ-sparing Intensity-modulated Radiotherapy for Anal Cancer using the ACTII Schedule: A Comparison of Conventional and Intensity-modulated Radiotherapy Plans, Clin Oncol, vol.25, issue.3, pp.155-61, 2013. ,
Intensity-Modulated Radiation Therapy vs. 3D Conformal Radiation Therapy for Squamous Cell Carcinoma of the Anal Canal, Gastrointest Cancer Res, vol.6, pp.39-45, 2013. ,
Tobacco smoking and risk of recurrence for squamous cell cancer of the anus, Cancer Detect Prev, vol.32, issue.2, pp.116-136, 2008. ,
Low-dose-rate interstitial brachytherapy boost for the treatment of anal canal cancers, Brachytherapy, vol.16, issue.1, pp.230-235, 2017. ,
HighDose Split-Course Radiation Therapy for Anal Cancer: Outcome Analysis Regarding the Boost Strategy (CORS-03 Study), Int J Radiat Oncol, vol.80, issue.3, pp.712-732, 2011. ,