, LomboVaortique!(20!Gy)! Anus!(45!Gy)+!IlioVinguinal!(50!Gy
, 28!séances!de!1,8!Gy! 36!+!32!jours! Boost! Non! 10,8!Gy!! Non! Non! Non! Curiethérapie!20!Gy!
,
! Endocrine! complications! in! longSterm! survivors! of! childhood!cancers, !Endocr!Relat!Cancer.!, vol.17, issue.3, 2010. ,
,
, Female! reproductive! health! after! childhood,! adolescent,! and! young! adult! cancers
, Clin!Oncol!Off!J!Am!Soc!Clin!Oncol.!, vol.31, issue.9, 2013.
! Fertility! preservation! for! young! patients! with!cancer:!who!is!at!risk!and!what!can!be!offered?, Lancet!Oncol.!, vol.6, issue.4, p.209, 2005. ,
,
, Cancer! and! fertility! preservation:! international! recommendations! from! an! expert! meeting, BMC!Med.!, p.14, 2016.
! Fertility! preservation! in! female! patients.! Hum! Reprod! Update, vol.10, pp.251-66, 2004. ,
! Endocrine! prevention! of! chemotherapySinduced! ovarian! failure, !Curr!Opin!Obstet!Gynecol.!, vol.28, issue.4, 2016. ,
! Secondary! amenorrhea! after! Hodgkin's! lymphoma! is! influenced! by! age! at! treatment,! stage! of! disease,! chemotherapy! regimen,! and! the! use! of! oral! contraceptives! during! therapy:! a! report! from! the! German! Hodgkin's! Lymphoma! Study! Group, J! Clin! Oncol! Off! J! Am! Soc! Clin!Oncol.!, vol.23, issue.30, 2005. ,
! Fertility! preservation! in! adolescents! and! young! adults!with!cancer, !J!Clin!Oncol!Off!J!Am!Soc!Clin!Oncol.!, 2010. ,
! Conservation! of! ovarian! tissue! in! the! treatment! of! carcinoma! of! the! cervix! with! radical! surgery, Am! J! Obstet! Gynecol.!, vol.75, issue.3, pp.590-600, 1958. ,
!transposition!in!young! women!and!fertility!sparing, Eur!Rev!Med!Pharmacol!Sci.!, vol.19, issue.18, pp.3418-3443, 2015. ,
,
! Ovarian! repositioning! in! pediatric! cancer! patients:!Flexible!techniques!accommodate!pelvic!radiation!fields.!Pediatr!Blood!Cancer, vol.49, pp.339-380, 2007. ,
,
Oncology! recommendations! on! fertility! preservation! in! cancer!patients, J!Clin!Oncol!Off!J!Am!Soc!Clin!Oncol.!, vol.24, issue.18, pp.2917-2948, 2006. ,
!Toxicity!of!chemotherapy! and!radiation!on!female!reproduction, !Clin!Obstet!Gynecol.!, 2010. ,
,
, , vol.39, 2010.
The! effects! of! radiotherapy! and! chemotherapy! on! female! reproduction.!Hum!Reprod!Update, vol.7, 2001. ,
,
! Ovarian! failure! following!abdominal!irradiation!in!childhood, !Br!J!Cancer, 1976. ,
Acute! ovarian! failure! in! the! childhood! cancer! survivor! study, J! Clin! Endocrinol! Metab.!, vol.91, issue.5, pp.1723-1731, 2006. ,
, The!radiosensitivity!of!the!human!oocyte
, , vol.18, 2003.
!transposition!in!prepubescent!and! adolescent!girls!with!cancer, Lancet!Oncol.!, vol.14, issue.13, 2013. ,
,
!Protection!of!ovarian!function!by!oral!contraceptives! in! women! receiving! chemotherapy! for! Hodgkin's! disease, vol.58, p.849, 1981. ,
! Ovarian! cryopreservation! for! fertility! preservation:!indications!and!outcomes.!Reprod!Camb!Engl, 2008. ,
! Impact! of! cancer! treatment! on! uterine! function, ! J! Natl!Cancer!Inst!Monogr.!, issue.34, 2005. ,
! Induction! of! ovulation! and! pregnancy!following!lateral!oophoropexy!for!Hodgkin's!disease, !Int!J!Gynaecol!Obstet!Off! Organ!Int!Fed!Gynaecol!Obstet.!, vol.33, issue.4, 1990. ,
,
, Radiotherapy!after!ovarian!transposition:!ovarian!function!and!fertility!preservation, !Int!
, , vol.25, 1993.
,
, Laparoscopic! ovarian! transposition! for! pelvic! malignancies:! indications! and! functional! outcomes.!Fertil!Steril, vol.70, 1998.
,
, Fertility! results! after! ovarian! transposition! for! pelvic! malignancies! treated! by! external! irradiation!or!brachytherapy.!Hum!Reprod!Oxf!Engl, 1998.
! Successful! surrogate! pregnancy! after! ovarian! transposition,! pelvic! irradiation! and! hysterectomy, ! J! Reprod! Med, 2004. ,
,
, Ovarian! transposition! before! pelvic! irradiation:! indications! and! functional! outcome, J! Obstet!Gynaecol!Res.!, vol.39, issue.11, 2013.
,
,
! Laparoscopic! lateral! ovarian! transposition! before! radiation! treatment!of!Hodgkin!disease, J!Am!Assoc!Gynecol!Laparosc, 1997. ,
,
!Oophoropexy!and!the!management! of! Hodgkin's! disease.! A! reevaluation! of! the! risks! and! benefits, ! Arch! Surg! Chic! Ill!, 1960. ,
,
! Laparoscopic! oophoropexy! and! ovarian! function!in!the!treatment!of!Hodgkin!disease.!Cancer, vol.86, pp.2138-2180, 1999. ,
,
, Ovarian! Suppression!With!Triptorelin!During!Adjuvant!Breast!Cancer!Chemotherapy!and!LongS term! Ovarian! Function,! Pregnancies,! and! DiseaseSFree! Survival:! A! Randomized! Clinical! Trial.!JAMA.!, vol.314, 2015.
,
, Evidence! for! the! Benefit! of! GonadotropinSReleasing! Hormone! Agonist! in! Preserving!
, Ovarian! Function! and! Fertility! in! Lymphoma! Survivors! Treated! With! Chemotherapy:!
, GonadotropinSReleasing! Hormone! Agonists! for! Ovarian! Function! Preservation! in!
, , 2016.
, Protecting! Ovaries! During!
,
, Obstet!Gynecol.!, vol.126, issue.1, 2015.
, ! GonadotropinSReleasing! Hormone! Agonist! !, vol.73
, Cotreatment! During! Chemotherapy! May! Increase! Pregnancy! Rate! in! Survivors.! The! Oncologist.!, vol.20, 2015.
! Preserving! fertility! when! choosing! chemotherapy! ,
GonadotropinSreleasing! hormone! analogues! for! the! prevention! of! chemotherapyS induced! premature! ovarian! failure! in! cancer! women:! systematic! review! and! metaS analysis!of!randomized!trials, !Cancer!Treat!Rev.!, vol.40, issue.5, pp.675-83, 2014. ,
, Temporary!Ovarian!Suppression!With!GonadotropinS Releasing! Hormone! Agonist! During! Chemotherapy! for! Fertility! Preservation:! Toward! the!End!of!the!Debate?!The!Oncologist, vol.20, 2015.
!The!immature! human! ovary! shows! loss! of! abnormal! follicles! and! increasing! follicle! developmental! competence! through! childhood! and! adolescence, ! Hum! Reprod! Oxf! Engl.!, vol.29, issue.1, pp.97-106, 2014. ,
!The! influence! of! sporadic! anovulation! on! hormone! levels! in! ovulatory! cycles, ! Hum! Reprod! Oxf!Engl.!, vol.28, issue.6, p.1687, 2013. ,
!cortex!transplantation:!time!to! move! on! from! experimental! studies! to! open! clinical! application.! Fertil! Steril, vol.104, pp.1097-1105, 2015. ,
,
Cancer& incidence& and& survival& in& adolescents& and& young& adults& in& France,& 2000E2008.& Pediatr& Hematol&Oncol.&2013&May, vol.30, pp.291-306 ,
,
, Lacour&B,&Clavel&J.&Présentation&des&dernières&données&d'incidence&et&de&mortalité& par& cancer& en& France& et& des& tendances& des& 25& dernières& années& (1980E2005).& Bull& Epidémiologique&Hebd.&2010&Dec&28
& The& Childhood& Cancer& Survivor& Study:& a& resource& for& research& of& ,
, & a& populationEbased& study& from& The& Association& of& the& French&Cancer&Registries&(FRANCIM).&Eur&J&Cancer&Oxf&Engl&1990.&2007&Jan, vol.43, p.149
, &Childhood& cancer&survivor&cohorts&in&Europe.&Acta&Oncol&Stockh&Swed, vol.54, issue.5, pp.655-68, 2015.
Profile:& the& French& childhood& cancer& survivor& study& for& leukaemia& (LEA& Cohort), & Int& J& Epidemiol, vol.44, issue.1, p.49, 2015. ,
,
, & Bull&Cancer&(Paris), vol.100, issue.7E8, 2013.
,
, Cardiac& Outcomes& in& Adult& Survivors& of& Childhood& Cancer& Exposed& to& Cardiotoxic& Therapy:&A&CrossEsectional&Study.&Ann&Intern&Med.&2016&Jan&19, vol.164, pp.93-101
, Cardiac& Outcomes& in& Survivors& of& Pediatric& and&Adult&Cancers.&Can&J&Cardiol, vol.32, issue.7, 2016.
&Pulmonary& complications& in& survivors& of& childhood& and& adolescent& cancer.& A& report& from& the& Childhood&Cancer&Survivor&Study.&Cancer.&2002&Dec&1, vol.95, pp.2431-2472 ,
, , p.&A&report&from&the&Childhood&
, &Paediatric&cancer&survivors&demonstrate&a&high& rate&of&subclinical&renal&dysfunction.&Pediatr&Blood&Cancer, vol.63, issue.11, pp.2026-2058, 2016.
&Early&and&late&renal&adverse&effects&after& potentially& nephrotoxic& treatment& for& childhood& cancer, & Cochrane& Database& Syst& Rev.&, issue.10, 2013. ,
,
, && Agence& de& biomédecine,& Institut& National& du& Cancer.& Conséquences& des& traitements& des& cancers& et& préservation& de& la& fertilité.& Etat& des& connaissances& et&
, Female& reproductive& health& after& childhood,& adolescent,& and& young& adult& cancers
Endocrine& complications& in& longEterm& survivors& of& childhood&cancers.&Endocr&Relat&Cancer.&2010&Sep, vol.17, pp.141-159 ,
, Sexuality& after& a& cancer& diagnosis:& A&
, & Having&children&after&surviving&cancer&in&childhood&or&adolescence&E&results&of&a&Berlin& survey.&Klin&Pädiatr, vol.220, issue.3, 2008.
,
&& & 25.&& Meirow&D,&Biederman&H,&Anderson&RA,&Wallace&WHB.&Toxicity&of&chemotherapy& and&radiation&on&female&reproduction.&Clin&Obstet&Gynecol.&2010&Dec, vol.39, pp.727-766, 2010. ,
, Ovarian& tissue& cryopreservation& and& transplantation& in& cancer& patients, & Best& Pract& Res& Clin&Obstet&Gynaecol, vol.24, issue.1, 2010.
,
, & Bull& Académie& Natl& 81&
, Médecine, vol.197, issue.4E5, pp.865-876, 2013.
,
, American& Society& of& Clinical& Oncology& recommendations& on& fertility& preservation& in& cancer&patients.&J&Clin&Oncol&Off&J&Am&Soc&Clin&Oncol.&2006&Jun&20, vol.24, pp.2917-2948
Fertility& preservation& for& young& patients& with&cancer:&who&is&at&risk&and&what&can&be&offered?&Lancet&Oncol, vol.6, p.209, 2005. ,
& Menstrual& patterns,& fertility& and& main& pregnancy& outcomes& after& allogeneic& haematopoietic& stem& cell&transplantation, &J&Obstet&Gynaecol&J&Inst&Obstet&Gynaecol, 20166. ,
Reproductive& potential& in& survivors& of& childhood& malignancy.&Pediatrician.&1991, vol.18 ,
, && Irtan&S,&Orbach&D,&Helfre&S,&Sarnacki&S.&Ovarian&transposition&in&prepubescent&and& adolescent&girls&with&cancer.&Lancet&Oncol.&2013&Dec, vol.14, pp.601-608
Conservation& of& ovarian& tissue& in& the& treatment& of& carcinoma& of& the& cervix& with& radical& surgery, & Am& J& Obstet& Gynecol.&, vol.75, issue.3, pp.590-600, 1958. ,
Ovarian& transposition& before& pelvic& irradiation:& indications& and& functional& outcome, & J& Obstet&Gynaecol&Res, vol.39, issue.11, 2013. ,
&Laparoscopic&unilateral&ovarian&transposition&prior&to&irradiation:&prospective&study& of&20&cases.&Cancer.&1996&Jun&15, vol.77 ,
,
, && Howard& FM.& Laparoscopic& lateral& ovarian& transposition& before& radiation& treatment&of&Hodgkin&disease.&J&Am&Assoc&Gynecol&Laparosc.&1997&Nov, vol.4, pp.601-605
A& new& approach& for& laparoscopic& ovarian& transposition& before& pelvic& irradiation, && & 39.&& Gabriel&DA,&Bernard&SA,&Lambert&J,&Croom&RD.&Oophoropexy&and&the&management& of& Hodgkin's& disease.& A& reevaluation& of& the& risks& and& benefits.& Arch& Surg& Chic& Ill&, vol.105, pp.1204-1210, 1960. ,
&& & 42.&& Lambertini&M,&Del&Mastro&L,&Pescio&MC,&Andersen&CY,&Azim&HA,&Peccatori&FA,&et&al.& Cancer& and& fertility& preservation:& international& recommendations& from& an& expert& meeting, vol.86, pp.2138-2180 ,
Fertility& preservation& in& female& patients.& Hum& Reprod& Update.&2004&Jun, vol.10, pp.251-66 ,
&Clinical&application&of&oocyte&vitrification:&a&systematic&review&and& metaEanalysis&of&randomized&controlled&trials.&Fertil&Steril.&2011&Aug, vol.96, pp.277-85 ,
, &adolescent,&and&young&adult&female&cancer&patient.&Curr&Opin&Obstet&Gynecol.&, vol.26, issue.5, pp.372-80, 2014.
Cryopreservation& of& human& embryos& by& vitrification& or& slow& freezing:& a& systematic& review&and&metaEanalysis.&Fertil&Steril.&2008&Jul, vol.90, pp.186-93 ,
, Cryopreservation& of& human& embryos& by& vitrification& or& slow& freezing:& which& one& is& better?& Curr& Opin& Obstet& Gynecol.&, 2009.
, &Gelbaya&TA,&Nardo&LG.&Oocyte&vitrification&in&the&21st¢ury&and&postE warming& fertility& outcomes:& a& systematic& review& and& metaEanalysis.& Reprod& Biomed& Online.&2014&Aug, vol.29, pp.159-76
, && Noyes&N,&Porcu&E,&Borini&A.&Over&900&oocyte&cryopreservation&babies&born&with& no& apparent& increase& in& congenital& anomalies.& Reprod& Biomed& Online.&, vol.18, pp.769-76, 2009.
Children& born& after& cryopreservation& of& embryos& or& oocytes:& a& systematic&review&of&outcome&data, &Hum&Reprod&Oxf&Engl, vol.24, issue.9, pp.2158-72, 2009. ,
Ovarian& function& after& transplantation& of& frozen,& banked& autologous&ovarian&tissue.&N&Engl&J&Med.&2000&Jun&22, vol.342 ,
, &Lancet&Lond&Engl.&2004& Oct&16, vol.364, pp.1405-1415
&Pregnancy& after& transplantation& of& cryopreserved& ovarian& tissue& in& a& patient& with& ovarian& failure& after&chemotherapy.&N&Engl&J&Med.&2005&Jul&21, vol.353, pp.318-339 ,
Orthotopic& reimplantation& of& cryopreserved& ovarian& cortical& strips& after& highEdose& & 84& chemotherapy& for& Hodgkin's& lymphoma.& Lancet& Lond& Engl.&, Apr&, vol.14, issue.9263, pp.1172-1177, 2001. ,
&Orthotopic&autotransplantation&of&cryopreserved&ovarian&tissue&to&a&woman& cured& of& cancer& E& follicular& growth,& steroid& production& and& oocyte& retrieval, & Reprod& Biomed&Online, vol.8, issue.4, 2004. ,
A& technique& for& transplantation& of& ovarian&cortical&strips&to&the&forearm.&Fertil&Steril.&2003&Jul, vol.80, pp.193-201 ,
, Z.& Endocrine& function&and&oocyte&retrieval&after&autologous&transplantation&of&ovarian&cortical&strips& to&the&forearm.&JAMA, vol.286, issue.12, 200126.
Autotransplantation& of& cryopreserved& ovarian& tissue:& a& procedure& with& promise,& risks,& and& a& need& for& a& registry, & Fertil& Steril.&, vol.95, issue.6, pp.1879-86, 2011. ,
Ovarian& cryopreservation& for& fertility& preservation:&indications&and&outcomes.&Reprod&Camb&Engl.&2008&Dec, vol.136, pp.681-690 ,
Fertility& preservation:& successful&transplantation&of&cryopreserved&ovarian&tissue&in&a&young&patient&previously& treated&for&Hodgkin's&disease.&The&Oncologist, vol.12, pp.1437-1479, 2007. ,
Treatment& history& and& outcome&of&24&deliveries&worldwide&after&autotransplantation&of&cryopreserved&ovarian& tissue,& including& two& new& Danish& deliveries& years& after& autotransplantation, J& Assist& Reprod&Genet, vol.31, issue.11, 2014. ,
&& & 63.&& Blumenfeld&Z,&Avivi&I,&Linn&S,&Epelbaum&R,&BenEShahar&M,&Haim&N.&Prevention&of& irreversible&chemotherapyEinduced&ovarian&damage&in&young&women&with&lymphoma&by& a& gonadotrophinEreleasing& hormone& agonist& in& parallel& to& chemotherapy, Hum& Reprod& Oxf&Engl, vol.99, issue.6, pp.1503-1516, 1996. ,
, Ovarian& Suppression&With&Triptorelin&During&Adjuvant&Breast&Cancer&Chemotherapy&and&LongE term& Ovarian& Function,& Pregnancies,& and& DiseaseEFree& Survival:& A& Randomized& Clinical& Trial, vol.314, 201522.
, No& Evidence& for& the& Benefit& of& GonadotropinEReleasing& Hormone& Agonist& in& Preserving& Ovarian& Function& and& Fertility& in& Lymphoma& Survivors& Treated& With& Chemotherapy:&
, GonadotropinEReleasing& Hormone& Agonists& for& Ovarian& Function& Preservation& in&
, Premenopausal& Women& Undergoing& Chemotherapy& for& EarlyEStage& Breast& Cancer:& A& Systematic&Review&and&MetaEanalysis.&JAMA&Oncol, 2016.
, Protecting& Ovaries& During& Chemotherapy& Through& Gonad& Suppression:& A& Systematic& Review& and& MetaEanalysis.& Obstet&Gynecol, vol.126, issue.1, 2015.
GonadotropinEReleasing& Hormone& Agonist& Cotreatment& During& Chemotherapy& May& Increase& Pregnancy& Rate& in& Survivors, & The& Oncologist, vol.20, issue.11, 2015. ,
Endocrine& prevention& of& chemotherapyEinduced& ovarian& 86& ,
Preserving& fertility& when& choosing& chemotherapy& regimens& E& the& role& of& gonadotropinEreleasing& hormone& agonists, & Expert& Opin& Pharmacother, vol.16, issue.7, 2015. ,
GonadotropinEreleasing& hormone& analogues& for& the& prevention& of& chemotherapyE induced& premature& ovarian& failure& in& cancer& women:& systematic& review& and& metaE analysis&of&randomized&trials, &Cancer&Treat&Rev, vol.40, issue.5, pp.675-83, 2014. ,
, Releasing& Hormone& Agonist& During& Chemotherapy& for& Fertility& Preservation:& Toward& the&End&of&the&Debate?&The&Oncologist.&2015&Nov, vol.20, pp.1233-1238
, &Sutcliffe&SB.&Protection&of&ovarian&function&by&oral&contraceptives& in& women& receiving& chemotherapy& for& Hodgkin's& disease.& Blood.& 1981& Oct, vol.58, p.849
Secondary& amenorrhea& after& Hodgkin's& lymphoma& is& influenced& by& age& at& treatment,& stage& of& disease,& chemotherapy& regimen,& and& the& use& of& oral& contraceptives& during& therapy:& a& report& from& the& German& Hodgkin's& Lymphoma& Study& Group, J& Clin& Oncol& Off& J& Am& Soc& Clin&Oncol, vol.23, issue.30, 200520. ,
, Lancet& Lond& Engl.&, vol.11, issue.9815, p.588, 2012.
& Case& report:& stimulation& of& puberty& in& a& girl& with& chemoE& and& radiation& therapy& induced& ovarian& failure& by& transplantation& of& a& small& part& of& her& frozen/thawed& ovarian& tissue.& Eur& J& Cancer&Oxf&Engl&1990, vol.49, 2013. ,
A& new& technique& to& protect& ovarian& function& before& pelvic& irradiation.& Heterotopic& ovarian& autotransplantation.& Cancer.&1987&Nov&1, vol.60 ,
,
, Engl, vol.30, issue.9, p.2107, 2015.
&& & 80.&& Hambridge&HL,&Mumford&SL,&Mattison&DR,&Ye&A,&Pollack&AZ,&Bloom&MS,&et&al.&The& influence& of& sporadic& anovulation& on& hormone& levels& in& ovulatory& cycles, & Hum& Reprod& Oxf& Engl.&, vol.29, issue.1, p.1687, 2013. ,
Laparoscopic& ovarian& transposition& for& pelvic& malignancies:& indications& and& functional& outcomes.&Fertil&Steril.&1998&Nov, vol.70 ,
Fertility& results& after& ovarian& transposition& for& pelvic& malignancies& treated& by& external& irradiation&or&brachytherapy.&Hum&Reprod&Oxf&Engl.&1998&Mar, vol.13, pp.660-663 ,
Successful& surrogate& pregnancy& after& ovarian& transposition,& pelvic& irradiation& and& hysterectomy, J& Reprod& Med.&, 2004. ,
Induction& of& ovulation& and& pregnancy&following&lateral&oophoropexy&for&Hodgkin's&disease.&Int&J&Gynaecol&Obstet&Off&, Organ&Int&Fed&Gynaecol&Obstet, vol.33, issue.4, 1990. ,
Radiotherapy&after&ovarian&transposition:&ovarian&function&and&fertility&preservation.&Int& J&Radiat&Oncol&Biol&Phys.&1993&Feb&15, vol.25 ,
Impact& of& cancer& treatment& on& uterine& function, & J& Natl&Cancer&Inst&Monogr, vol.34, 2005. ,
Preservation& of& ovarian& function& by& ovarian& transposition& performed& before& pelvic& irradiation&during&childhood.&J&Pediatr.&1992&Dec, vol.121 ,
&Safety&and& usefulness& of& cryopreservation& of& ovarian& tissue& to& preserve& fertility:& a& 12Eyear& retrospective&analysis.&Hum&Reprod&Oxf&Engl.&2014&Sep, && Prasath&EB, vol.29, issue.9 ,
Outcomes& of& ovarian& transposition& in& gynaecological& cancers;& a& systematic& review& and& metaEanalysis, & J& Ovarian&Res, vol.7, p.69, 2014. ,
&& & 92.&& De&Lambert&G,&Poirot&C,&Guérin&F,&Brugières&L,&Martelli&H.&[Preservation&of&fertility& in&children&with&cancer].&Bull&Cancer&(Paris).&2015&May, &Ovarian&transposition&in&young& women&and&fertility&sparing.&Eur&Rev&Med&Pharmacol&Sci, vol.19, issue.18, pp.436-478, 2015. ,