A. P. , , 1990.

A. B. , Z. M. , and B. A. , Surface Activity and Energetic of Aggregate Formation in Aqueous Sodium Benzoate and Salicylate Solutions, Journal of Dispersion Science and Technology, vol.16, issue.6, pp.451-68, 1995.

A. A. Souto-e, Solid Lipid Nanoparticles as a Drug Delivery System for Peptides and Proteins, Advanced Drug Delivery Reviews, vol.59, issue.6, pp.478-90, 2007.

A. D. Moghimi-s and Y. A. , Cubosomes and Hexosomes as Versatile Platforms for Drug Delivery, Therapeutic Delivery, vol.6, issue.12, pp.1347-64, 2015.

B. J. Cagna-a and . H. Lucassen-reynders-e, Viscoelastic Properties of Triacylglycerol/Water Interfaces Covered by Proteins, Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol.114, issue.8, pp.245-54, 1996.

P. E. Bermann, Aging Skin : Causes, Treatments, and Prevention, Nursing Clinics of North America, vol.42, issue.3, pp.485-500, 2007.
DOI : 10.1016/j.cnur.2007.05.001

B. D. Bierganns, P. , B. N. , T. R. , and S. C. , New Speciality Surfactants with Natural Structural Motifs, New Journal of Chemistry, vol.30, issue.12, p.1705, 2006.

B. N. , Les cellules de Merkel, Kératin, vol.12, pp.4-8, 2007.

B. B. , W. D. , K. S. , and D. G. , Lyotropic Liquid Crystalline Phases Formed from Glycerate Surfactants as Sustained Release Drug Delivery Systems, International Journal of Pharmaceutics, vol.309, issue.1-2, pp.218-244, 2006.

B. G. Molinari-a, Liposomes as Nanomedical Devices, International Journal of Nanomedicine, vol.10, issue.2, pp.975-999, 2015.

. Brannan-d, Cosmetic preservation, Journal of the society of cosmetic chemists, vol.46, issue.8, pp.199-220, 1995.

C. C. Fabre-p and R. E. Veyssie-m, Janus Beads" : realization and behaviour at water/oil interfaces, Europhysics Letters, vol.9, issue.3, p.251, 1989.

C. G. Schätzlein-a and . Richardsen-h, Ultradeformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements, Biochimica et Biophysica Acta-Biomembranes, vol.1564, issue.1, 2002.

C. N. , J. B. Hao-q, and H. T. , Simple Fabrication of Snowman-like Colloids, Journal of Colloid and Interface Science, vol.371, issue.1, pp.28-33, 2012.

C. Y. Ma-p and G. S. , Cubic and Hexagonal Liquid Crystals as Drug Delivery Systems, BioMed Research International, vol.2014, pp.1-12, 2014.

C. I. Lee-k, Morphology of latex particles formed by poly (methyl methacrylate)seeded emulsion polymerization of styrene, Journal of applied polymer science, vol.30, issue.5, pp.1903-1926, 1985.

D. G. Bayless-k, D. M. , and M. G. , Regulation of Tissue Injury Responses by the Exposure of Matricryptic Sites within Extracellular Matrix Molecules, The American Journal of Pathology, vol.156, issue.5, pp.1489-98, 2000.

D. , Structure briques mortier du stratum corneum.?en ligne? Consulté le 21 septembre, Bodylanguage.fr, 2016.

D. H. Dormidontova and E. E. , Kinetics of Nanoparticle Targeting by Dissipative Particle Dynamics Simulations, Biomacromolecules, vol.10, issue.11, pp.3089-97, 2009.

D. J. Fang-c and C. L. White, Measurement of interfacial tension in fluid-fluid systems, Encyclopedia of surface and colloid science, vol.3, pp.3158-3163, 2002.

D. J. O'reilly-r, Anisotropic particles with patchy, multicompartment and Janus architectures: preparation and application, Chemical Society Reviews, vol.40, issue.5, p.2402, 2011.

F. V. Lesieur-s, O. M. Ollivon-m, and . Truong-t, Nanoparticules lipidiques multicompartimentées. WO2015011419A1, 2014.

F. J. , Prodrug strategy for enhancing drug delivery via skin, Current drug discovery technologies, vol.3, issue.3, pp.211-224, 2006.

F. , Guidance for Industry. Manufacturing, Processing, or Holding Active Pharmaeuticals Ingredients, 1998.

F. K. , The Outer Frontier : The Importance of Lipid Metabolism in the Skin, The Journal of Lipid Research, vol.50, pp.417-439, 2008.

F. C. , D. A. , H. A. , B. J. , and D. , Positron Annihilation Lifetime Spectroscopy (PALS): A Probe for Molecular Organisation in Self-Assembled Biomimetic Systems, Phys. Chem. Chem. Phys, vol.17, issue.27, pp.17527-17567, 2015.

G. F. Maibach and H. I. , Role of Topical Peptides in Preventing or Treating Aged Skin, International Journal of Cosmetic Science, vol.31, issue.5, pp.327-372, 2009.

G. H. Yang-z, G. J. , and C. C. Xu-b, Heterodimers of Nanoparticles: Formation at a Liquid?Liquid Interface and Particle-Specific Surface Modification by Functional Molecules, Journal of the American Chemical Society, vol.127, issue.1, pp.34-35, 2005.

H. J. , Skin, the final frontier, International Journal of Pharmaceutics, vol.224, issue.1, pp.1-18, 2001.

H. M. Achahbar-a, K. J. El, K. B. , F. V. , and A. O. Bresson-s, Lyotropic Behavior of Gelucire 50/13 by XRD, Raman and IR Spectroscopies according to Hydration, Chemistry and Physics of Lipids, vol.200, issue.6, pp.11-23, 2016.

H. De-graaff-a.m, W. H. Groenink, and B. J. , The in Vivo and in Vitro Interactions of Elastic and Rigid Vesicles with Human Skin, Biochimica et Biophysica Acta-General Subjects, vol.1573, issue.2, pp.130-170, 2002.

H. S. , Lipid-based nano-delivery systems for skin delivery of drugs and bioactives, Frontiers in Pharmacology, 2015.

H. S. , Differentially Degradable Janus Particles for Controlled Release Applications, Macromolecular Rapid Communications, vol.33, issue.14, pp.1178-83, 2012.

I. J. , M. D. , and N. B. , Theory of self-assembly of hydrocarbon amphiphiles into micelles and bilayers, Journal of the Chemical Society, vol.2, pp.1525-1568, 1976.

J. V. Rodier-j and M. J. , Polyoxylglycerides and Glycerides: Effects of Manufacturing Parameters on API Stability, Excipient Functionality and Processing, International Journal of Pharmaceutics, vol.466, issue.1-2, pp.109-130, 2014.

J. R. Castelletto-v, C. C. , and H. I. , Collagen Stimulating Effect of Peptide Amphiphile C16-KTTKS on Human Fibroblasts, Molecular Pharmaceutics, vol.10, issue.3, pp.1063-69, 2013.

K. J. and H. J. , Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems, International journal of pharmaceutics, vol.417, issue.1-2, pp.120-157, 2011.

L. M. Hatton and T. A. , Synthesis, Properties and Applications of Janus Nanoparticles, Nano Today, vol.6, issue.3, pp.286-308, 2011.

L. K. Peschard-o, Biologically active peptides : from a laboratory bench curiosity to a functional skin care product, International journal of cosmetic science, vol.22, issue.3, pp.207-218, 2000.

L. B. Wei-w, Q. X. , and Y. Z. , Janus Colloids Formed by Biphasic, p.79, 2008.

, Pickering Emulsion Interface, Angewandte Chemie, vol.120, issue.21, pp.4037-4076

M. F. Pasco-s, R. L. , H. W. , and M. , An Introduction to Matrikines: Extracellular Matrix-Derived Peptides Which Regulate Cell Activity, Critical Reviews in Oncology/Hematology, vol.49, issue.3, pp.199-202, 2004.

M. M. , et b. Introduction à la dermopharmacie et à la cosmétologie. Editions médicales internationales, 2003.

. K. Menon-g and L. W. Cleary-g, The Structure and Function of the Stratum Corneum, International Journal of Pharmaceutics, vol.435, issue.1, pp.3-9, 2012.

M. T. Machida-y and H. F. , An Application of the Phase-InversionTemperature Method to the Emulsification of Cosmetics. I. Factors Affecting the PhaseInversion Temperature, Bulletin of the Chemical Society of Japan, vol.43, issue.10, pp.3044-3092, 1970.

M. N. , E. , E. , and H. N. , Morphometry and Epidermal Fas Expression of Unexposed Aged versus Young Skin, Indian Journal of Dermatology, vol.57, issue.3, p.181, 2012.

. S. Orth-d, Cosmetic and drug microbiology. Cosmetic science and technology 31, 2006.

P. H. and R. R. Agarwal-v, Liposome and Their Applications in Cancer Therapy, Brazilian Archives of Biology and Technology, vol.59, 2016.

P. J. Hommoss-a and M. R. , Lipid Nanoparticles (SLN, NLC) in Cosmetic and Pharmaceutical Dermal Products, International Journal of Pharmaceutics, vol.366, issue.1-2, pp.170-84, 2009.

P. A. Reculusa-s, R. , B. , and D. E. , Design and Synthesis of Janus Micro-and Nanoparticles, Journal of Materials Chemistry, vol.15, p.3745, 2005.

P. L. Vasquez-soltero-j.m, GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration, BioMed Research International, vol.2015, pp.1-7, 2015.

R. F. Winkler-j.s, R. R. , and T. M. , Production and Characterization of Anisotropic Particles from Biodegradable Materials, Langmuir, vol.28, issue.8, pp.3756-65, 2012.

S. C. , T. , T. , G. C. , L. C. et al., Innovative lipid-based Janus nanoparticules : Formulation, preparation and cosmetic applications, 2014.

. F. Schaefer-u, . Hansen-s, L. Schneider-m, and L. C. Contreras-j, Models for skin absorption and skin toxicity testing. Drug absorption studies, pp.3-33, 2008.

J. M. Seddon, Structure of the Inverted Hexagonal (HII) Phase, and Non-Lamellar Phase Transitions of Lipids, Biochimica Et Biophysica Acta, vol.1031, issue.1, pp.1-69, 1990.

S. K. Arai-h, The Correlation between Phase Inversion Temperature In Emulsion and Cloud Point in Solution of Nonionic Emulsifier, The Journal of Physical Chemistry, vol.68, issue.12, pp.3485-90, 1964.

S. A. Wegrowski-y and M. F. Bontemps-y, Expression of Glycosaminoglycans and Small Proteoglycans in Wounds : Modulation by the Tripeptide-Copper Complex Glycyl-L-Histidyl-L-Lysine-Cu 2+, Journal of Investigative Dermatology, vol.115, issue.6, pp.962-968, 2000.

S. J. Janssens-m, G. G. , and B. J. , The Important Role of Stratum Corneum Lipids for the Cutaneous Barrier Function, Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, vol.1841, issue.3, pp.295-313, 2014.

S. E. Müller-r, Cosmetic features and applications of lipid nanoparticles (SLN, NLC), International Journal of Cosmetic Science, vol.30, issue.3, pp.157-165, 2008.

. T. Spicer-p, Progress in Liquid Crystalline Dispersions : Cubosomes, Current Opinion in Colloid & Interface Science, vol.10, issue.5-6, pp.274-79, 2005.

S. T. Du, J. , Y. Y. , M. C. , D. S. et al., Simultaneous Delivery of siRNA and Paclitaxel via a, 2011.

, Micelleplex Promotes Synergistic Tumor Suppression, ACS Nano, vol.5, issue.2, pp.1483-94

T. T. , Emulsion Formation, Stability, and Rheology. First Edition, 2013.

T. E. Dayan-n, B. L. Godin-b, and E. , Ethosomes-novel vesicular carriers for enhanced delivery: characterization and skin penetration properties, Journal of Controlled Release, vol.65, issue.3, pp.403-418, 2000.

T. K. Lamb-p and D. , Matrikines and Matricryptins: Implications for Cutaneous Cancers and Skin Repair, Journal of Dermatological Science, vol.40, issue.1, pp.11-20, 2005.

T. C. Lesieur-s, Janus Nanoparticles: Materials, Preparation and Recent Advances in Drug Delivery, Expert Opinion on Drug Delivery, pp.1-14, 2014.

U. O. Ogbonna and A. A. , Nanoparticles for Dermal, p.81, 2014.

, Transdermal Drug Delivery. Application of Nanotechnology in Drug Delivery

S. J. Valenzuela-p, Nanoparticle Delivery for Transdermal HRT, Nanomedicine: Nanotechnology, Biology and Medicine, pp.83-89, 2012.

W. J. Maibach and H. I. , Age and skin structure and function, a quantitative approach (II) : protein, glycosaminoglycan, water, and lipid content and structure, Skin research and technology, vol.12, issue.3, pp.145-154, 2006.

W. A. Andre-x, D. M. , A. V. , and M. A. , Janus Discs. Journal of the American Chemical Society, vol.129, pp.6187-98, 2007.

W. A. Müller-a, Janus Particles: Synthesis, Self-Assembly, Physical Properties, and Applications, vol.113, pp.5194-5261, 2013.

W. A. Barry-b, Penetration Enhancers. Advanced Drug Delivery Reviews, vol.64, issue.12, pp.128-165, 2012.

X. H. She-z, W. S. Sharma-g, and S. J. , One-Step Fabrication of Polymeric Janus Nanoparticles for Drug Delivery, Langmuir, vol.28, issue.9, pp.4459-63, 2012.

Z. L. Falla and T. J. , Cosmeceuticals and Peptides, Clinics in Dermatology, vol.27, issue.5, pp.485-94, 2009.