, Rate ratios with 95% confidence interval refers to increase in expected event rate per standard deviation of log-transformed change in biomarker between baseline and 16 weeks after randomization, adjusted for baseline value alone (left columns) or baseline value and clinical covariates (right column). The following covariates were included: treatment group, age, sex, region, history of stroke diabetes, hypertension, MI, ischemic cause of HF or AF, NYHA, LVEF, medications (MRA, Diuretic, BB), systolic and BP, eGFR and serum potassium, NT-proBNP, and high sensitivity troponin

H. Hr and . Ratio,