Polylactide Perspectives in Biomedicine: From Novel Synthesis to the Application Performance - Université de Lorraine Access content directly
Journal Articles Pharmaceutics Year : 2022

Polylactide Perspectives in Biomedicine: From Novel Synthesis to the Application Performance

Joaquín González-Fuentes
  • Function : Author
Iván Bravo
Carlos Alonso-Moreno
Daniel Hermida-Merino
  • Function : Correspondent author
  • PersonId : 1087097

Connectez-vous pour contacter l'auteur

Abstract

The incessant developments in the pharmaceutical and biomedical fields, particularly, customised solutions for specific diseases with targeted therapeutic treatments, require the design of multicomponent materials with multifunctional capabilities. Biodegradable polymers offer a variety of tailored physicochemical properties minimising health adverse side effects at a low price and weight, which are ideal to design matrices for hybrid materials. PLAs emerge as an ideal candidate to develop novel materials as are endowed withcombined ambivalent performance parameters. The state-of-the-art of use of PLA-based materials aimed at pharmaceutical and biomedical applications is reviewed, with an emphasis on the correlation between the synthesis and the processing conditions that define the nanostructure generated, with the final performance studies typically conducted with either therapeutic agents by in vitro and/or in vivo experiments or biomedical devices.
No file

Dates and versions

hal-03781182 , version 1 (20-09-2022)

Identifiers

Cite

Carmen Moya-Lopez, Joaquín González-Fuentes, Iván Bravo, David Chapron, Patrice Bourson, et al.. Polylactide Perspectives in Biomedicine: From Novel Synthesis to the Application Performance. Pharmaceutics, 2022, 14 (8), pp.1673. ⟨10.3390/pharmaceutics14081673⟩. ⟨hal-03781182⟩
25 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More