Insights into docking in megasynthases from the investigation of the toblerol trans -AT polyketide synthase: many α-helical means to an end - Université de Lorraine
Article Dans Une Revue RSC Chemical Biology Année : 2024

Insights into docking in megasynthases from the investigation of the toblerol trans -AT polyketide synthase: many α-helical means to an end

Résumé

This work identifies a novel class of docking domains (DDs) from the toblerol modular trans -AT polyketide synthase (PKS) and establishes previously unrecognised architectural relationships between known types of DDs.

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Sciences du Vivant [q-bio]

Kira Weissman-Sourmail  : Connectez-vous pour contacter le contributeur

https://hal.univ-lorraine.fr/hal-04644892

Soumis le : jeudi 11 juillet 2024-12:11:07

Dernière modification le : mardi 27 août 2024-03:15:11

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Dates et versions

hal-04644892 , version 1 (11-07-2024)

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Serge Scat, Kira Weissman, Benjamin Chagot. Insights into docking in megasynthases from the investigation of the toblerol trans -AT polyketide synthase: many α-helical means to an end. RSC Chemical Biology, 2024, 5 (7), pp.669-683. ⟨10.1039/d4cb00075g⟩. ⟨hal-04644892⟩

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