C. Beigelman-aubry, C. Hill, and P. Grenier, Management of an incidentally discovered pulmonary nodule, European Radiology, vol.20, issue.suppl 2, pp.449-466, 2007.
DOI : 10.1093/oxfordjournals.aje.a010153

D. Ost and A. Fein, Management strategies for the solitary pulmonary nodule, Current Opinion in Pulmonary Medicine, vol.10, issue.4, pp.272-278, 2004.
DOI : 10.1097/01.mcp.0000130322.11513.c8

G. Lillington, Management of solitary pulmonary nodules, Dis Mon, vol.37, pp.271-318, 1991.

G. Herder, H. Van-tinteren, R. Golding, P. Kotense, E. Comans et al., Clinical Prediction Model To Characterize Pulmonary Nodules, Chest, vol.128, issue.4, pp.2490-2496, 2005.
DOI : 10.1378/chest.128.4.2490

R. 1. Beigelman-aubry, C. Hill, C. Grenier, and P. A. , Management of an incidentally discovered pulmonary nodule, European Radiology, vol.20, issue.suppl 2, pp.449-466, 2007.
DOI : 10.1093/oxfordjournals.aje.a010153

D. Ost and A. Fein, Management strategies for the solitary pulmonary nodule, Current Opinion in Pulmonary Medicine, vol.10, issue.4, pp.272-278, 2004.
DOI : 10.1097/01.mcp.0000130322.11513.c8

G. A. Lillington, Management of solitary pulmonary nodules. Disease-a-Month, pp.271-318, 1991.

R. T. Greenlee, M. B. Hill-harmon, T. Murray, and M. Thun, Cancer Statistics, 2001, Cancer statistics, pp.15-36, 2001.
DOI : 10.3322/canjclin.51.1.15

A. Jemal, A. Thomas, T. Murray, and M. Thun, Cancer Statistics, 2002, Cancer statistics, pp.23-47, 2002.
DOI : 10.3322/canjclin.52.1.23

S. J. Swanson, M. T. Jaklitsch, S. J. Mentzer, R. Bueno, J. M. Lukanich et al., Management of the Solitary Pulmonary Nodule, Chest, vol.116, issue.6, pp.116-523, 1999.
DOI : 10.1378/chest.116.suppl_3.523S

K. Alzahouri, M. Velten, P. Arveux, M. C. Woronoff-lemsi, D. Jolly et al., Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts, BMC Cancer, vol.138, issue.1, p.93, 2008.
DOI : 10.7326/0003-4819-138-9-200305060-00009

G. A. Lillington, Management of solitary pulmonary nodules, Postgraduate Medicine, vol.153, issue.1, pp.145-150, 1997.
DOI : 10.1164/ajrccm.153.1.8542152

G. Trunk, D. R. Gracey, and R. B. Byrd, The Management and Evaluation of the Solitary Pulmonary Nodule, Chest, vol.66, issue.3, pp.236-239, 1974.
DOI : 10.1378/chest.66.3.236

S. Beijer, G. I. Kempen, M. C. Pijls-johannesma, A. De-graeff, and P. C. Dagnelie, Determinants of overall quality of life in preterminal cancer patients, International Journal of Cancer, vol.39, issue.1, pp.232-235, 2008.
DOI : 10.1159/000100450

M. Lheureux, C. Raherison, J. M. Vernejoux, L. Nguyen, C. Nocent et al., Quality of life in lung cancer: does disclosure of the diagnosis have an impact?, Lung Cancer, vol.43, issue.2, pp.175-182, 2004.
DOI : 10.1016/j.lungcan.2003.08.018

A. Montazeri, C. R. Gillis, and J. Mcewen, Quality of Life in Patients With Lung Cancer, Chest, vol.113, issue.2, pp.467-481, 1970.
DOI : 10.1378/chest.113.2.467

A. Montazeri, R. Milroy, D. Hole, J. Mcewen, and C. R. Gillis, How quality of life data contribute to our understanding of cancer patients' experiences? A study of patients with lung cancer, Quality of Life Research, vol.12, issue.2, pp.157-166, 2003.
DOI : 10.1023/A:1022232624891

F. Efficace, A. Bottomley, E. F. Smit, P. Lianes, C. Legrand et al., Is a patient's self-reported healthrelated quality of life a prognostic factor for survival in nonsmall-cell lung cancer patients? A multivariate analysis of 108, 2006.

H. Langendijk, N. K. Aaronson, J. M. De-jong, G. P. Ten-velde, M. J. Muller et al., The prognostic impact of quality of life assessed with the EORTC QLQ-C30 in inoperable non-small cell lung carcinoma treated with radiotherapy, Radiotherapy and Oncology, vol.55, issue.1, pp.19-25, 2000.
DOI : 10.1016/S0167-8140(00)00158-4

A. Montazeri, R. Milroy, D. Hole, J. Mcewen, and . Gillis, Quality of life in lung cancer patients: As an important prognostic factor, C. R. Lung Cancer, vol.31, pp.2-3, 2001.

M. A. Testa and D. C. Simonson, Assessment of Quality-of-Life Outcomes, New England Journal of Medicine, vol.334, issue.13, pp.835-840, 1996.
DOI : 10.1056/NEJM199603283341306

R. W. Van-gerth, Assessment of quality of life: advantages and pitfalls, Clinical <html_ent glyph="@amp;" ascii="&"/> Experimental Allergy Reviews, vol.104, issue.1, pp.32-35, 2005.
DOI : 10.1001/jama.286.23.2956

W. The and . Group, Study protocol for the World Health Organization project to develop a Quality of Life assessment instrument (WHOQOL), Quality of Life Research, vol.2, issue.2, pp.153-159, 1993.

A. Brédart and S. Dolbeault, Quality of life assessment in oncology: I. Definitions and objectives, Review of Francopoh Psycho-Oncologie, vol.1, pp.7-11, 2005.

I. Lemonnier, C. Baumann, N. Jay, K. Alzahouri, P. Arveux et al., Does the availability of positron emission tomography modify diagnostic strategies for solitary pulmonary nodules? An observational study in France, BMC Cancer, vol.18, issue.1, p.139, 2009.
DOI : 10.1007/s00330-008-0970-5

URL : https://hal.archives-ouvertes.fr/hal-00475551

J. E. Brazier, R. Harper, N. M. Jones, A. O-'cathain, K. J. Thomas et al., Validating the SF-36 health survey questionnaire: new outcome measure for primary care., BMJ, vol.305, issue.6846, pp.305-160, 1992.
DOI : 10.1136/bmj.305.6846.160

J. J. Ware and C. D. Sherbourne, The MOS 36-ltem Short-Form Health Survey (SF-36), Medical Care, vol.30, issue.6, pp.473-783, 1992.
DOI : 10.1097/00005650-199206000-00002

M. H. Frost, A. E. Bonomi, C. E. Ferrans, G. Y. Wong, and R. D. Hays, Patient, clinician, and population perspectives on determining the clinical significance of quality-of-life scores, pp.77-488, 2002.

A. Brunelli, L. Socci, M. Refai, M. Salati, F. Xiume et al., Quality of life before and after major lung resection for lung cancer: A prospective follow-up analysis. The Annals of Thoracic Surgery, pp.410-416, 2007.

J. R. Handy, . Jr, J. W. Asaph, L. Skokan, C. E. Reed et al., What Happens to Patients Undergoing Lung Cancer Surgery?, Chest, vol.122, issue.1, pp.21-30, 2002.
DOI : 10.1378/chest.122.1.21

J. Alonso, M. Ferrer, B. Gandek, J. E. Ware, . Jr et al., Health-related quality of life associated with chronic conditions in eight countries: Results from the International Quality of Life Assessment (IQOLA) Project, Quality of Life Research, vol.13, issue.2, pp.283-298, 2004.
DOI : 10.1023/B:QURE.0000018472.46236.05

O. Lababede, M. A. Meziane, and T. W. Rice, TNM Staging of Lung Cancer, Chest, vol.115, issue.1, pp.233-235, 1999.
DOI : 10.1378/chest.115.1.233

C. Perrotin, P. Lemeunier, D. Grahek, T. Molina, A. Petino et al., R??sultats de la TEP [18F]-FDG dans la stadification pr??op??ratoire des tumeurs pulmonaires, Revue des Maladies Respiratoires, vol.22, issue.4, pp.579-585, 2005.
DOI : 10.1016/S0761-8425(05)85610-4

J. H. Schiller, Current Standards of Care in Small-Cell and Non-Small-Cell Lung Cancer, Oncology, vol.61, issue.1, pp.61-64, 2001.
DOI : 10.1159/000055386

M. T. King, The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30, Quality of Life Research, vol.311, issue.6, pp.555-567, 1996.
DOI : 10.1007/BF00439229

R. D. Crosby, R. L. Kolotkin, and G. R. Williams, Defining clinically meaningful change in health-related quality of life, Journal of Clinical Epidemiology, vol.56, issue.5, pp.395-407, 2003.
DOI : 10.1016/S0895-4356(03)00044-1

J. D. Cooper, Management of the solitary pulmonary nodule: Directed resection, Seminars in Thoracic and Cardiovascular Surgery, vol.14, issue.3, pp.286-291, 2002.
DOI : 10.1053/stcs.2002.33430

C. Lejeune, A. Zahouri, K. Woronoff-lemsi, M. C. Arveux, P. Bernard et al., Use of a decision analysis model to assess the medicoeconomic implications of FDG PET imaging in diagnosing a solitary pulmonary nodule, The European Journal of Health Economics, vol.12, issue.3, pp.203-214, 2005.
DOI : 10.7326/0003-4819-138-9-200305060-00009

B. B. Tan, K. R. Flaherty, E. A. Kazerooni, and M. D. Iannettoni, The Solitary Pulmonary Nodule*, Chest, vol.123, issue.1, pp.89-96, 2003.
DOI : 10.1378/chest.123.1_suppl.89S

N. Dewan, N. Gupta, L. Redepenning, J. Phalen, and M. Frick, Diagnostic Efficacy of PET-FDG Imaging in Solitary Pulmonary Nodules, Chest, vol.104, issue.4, pp.997-1002, 1993.
DOI : 10.1378/chest.104.4.997

M. Gould, W. Kuschner, C. Rydzak, C. Maclean, A. Demas et al., Test Performance of Positron Emission Tomography and Computed Tomography for Mediastinal Staging in Patients with Non???Small-Cell Lung Cancer, Annals of Internal Medicine, vol.139, issue.11, pp.879-892, 2003.
DOI : 10.7326/0003-4819-139-11-200311180-00013

G. Jerusalem, R. Hustinx, Y. Beguin, and G. Fillet, PET scan imaging in oncology, European Journal of Cancer, vol.39, issue.11, pp.1525-1534, 2003.
DOI : 10.1016/S0959-8049(03)00374-5

V. Lowe and K. Naunheim, Current role of positron emission tomography in thoracic oncology, Thorax, vol.53, issue.8, pp.703-712, 1998.
DOI : 10.1136/thx.53.8.703

F. Vaylet, A. Bonnichon, Y. Salles, E. Gontier, G. Bonardel et al., La tomographie par????mission de??positons au??18fluorod??soxyglucose (18FDG-TEP) dans??la??prise en??charge du??cancer bronchique non ????petites cellules en??2006, Cancer/Radioth??rapie, vol.11, issue.1-2, pp.16-22, 2006.
DOI : 10.1016/j.canrad.2006.10.003

C. Rest, C. , and V. D. La, TEP: un nouvel outil d'imagerie fonctionnelles (principe, applications validées, perspectives), Médecine thérapeutique, vol.10, issue.3, pp.170-177, 2004.

V. Kalff, R. Hicks, M. Macmanus, D. Binns, A. Mckenzie et al., F Fluorodeoxyglucose Positron Emission Tomography in Patients With Non???Small-Cell Lung Cancer: A Prospective Study, Journal of Clinical Oncology, vol.19, issue.1, pp.111-118, 2001.
DOI : 10.1200/JCO.2001.19.1.111

G. Pepe, C. Rossetti, S. Sironi, C. Landoni, L. Gianolli et al., Patients with known or suspected lung cancer: evaluation of clinical management changes due to 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) study, Nuclear Medicine Communications, vol.26, issue.9, pp.831-837, 2005.
DOI : 10.1097/01.mnm.0000175787.04553.99

S. Sachs and T. Bilfinger, The Impact of Positron Emission Tomography on Clinical Decision Making in a University-Based Multidisciplinary Lung Cancer Practice, Chest, vol.128, issue.2, pp.698-703, 2005.
DOI : 10.1378/chest.128.2.698

A. Pecking, C. Corone, J. Talbolt, and J. Moretti, Cancers broncho-pulmonaires et 18 fluorodéoxyglucose Centre Rene Huguenin, Disponibilité sur Internet, 2006.

K. Alzahouri, C. Lejeune, M. Woronoff-lemsi, P. Arveux, and F. Guillemin, Cost-effectiveness analysis of strategies introducing FDG-PET into the mediastinal staging of non-small-cell lung cancer from the French healthcare system perspective, Clinical Radiology, vol.60, issue.4, pp.479-492, 2005.
DOI : 10.1016/j.crad.2004.10.010

J. Buscombe, O. Rourke, and E. , F FDG PET-CT cost effective in lung cancer?, Expert Review of Anticancer Therapy, vol.24, issue.4, pp.471-476, 2007.
DOI : 10.1200/JCO.2005.02.4695

S. Gambhir, C. Hoh, M. Phelps, I. Madar, and J. Maddahi, Decision tree sensitivity analysis for cost-effectiveness of FDG-PET in the staging and management of nonsmall-cell lung carcinoma, J Nucl Med, vol.37, issue.9, pp.1428-1436, 1996.

S. Gambhir, J. Shepherd, B. Shah, E. Hart, C. Hoh et al., Analytical decision model for the cost-effective management of solitary pulmonary nodules., Journal of Clinical Oncology, vol.16, issue.6, pp.2113-2125, 1998.
DOI : 10.1200/JCO.1998.16.6.2113

M. Gould, G. Sanders, P. Barnett, C. Rydzak, C. Maclean et al., Cost-Effectiveness of Alternative Management Strategies for Patients with Solitary Pulmonary Nodules, Annals of Internal Medicine, vol.138, issue.9, pp.724-735, 2003.
DOI : 10.7326/0003-4819-138-9-200305060-00009

S. Kosuda, K. Ichihara, M. Watanabe, H. Kobayashi, and S. Kusano, Decision-Tree Sensitivity Analysis for Cost-Effectiveness of Chest 2-Fluoro-2-D-[18F]Fluorodeoxyglucose Positron Emission Tomography in Patients With Pulmonary Nodules (Non-small Cell Lung Carcinoma) in Japan, Chest, vol.117, issue.2, pp.346-353, 2000.
DOI : 10.1378/chest.117.2.346

S. Van-hung-nguyen, Y. Péloquin, and . Lacasse, Cost Effectiveness of Positron Emission Tomography for the Management of Potentially Operable Non-Small Cell Lung Cancer in Quebec, Canadian Respiratory Journal, vol.12, issue.1, pp.19-25, 2005.
DOI : 10.1155/2005/612387

F. Efficace, A. Bottomley, E. Smit, P. Lianes, C. Legrand et al., Is a patient's self-reported health-related quality of life a prognostic factor for survival in non-small-cell lung cancer patients? A multivariate analysis of prognostic factors of EORTC study 08975, Annals of Oncology, vol.17, issue.11, pp.1698-1704, 2006.
DOI : 10.1093/annonc/mdl183

H. Langendijk, N. Aaronson, J. De-jong, G. Velde, M. Muller et al., The prognostic impact of quality of life assessed with the EORTC QLQ-C30 in inoperable non-small cell lung carcinoma treated with radiotherapy, Radiotherapy and Oncology, vol.55, issue.1, pp.19-25, 2000.
DOI : 10.1016/S0167-8140(00)00158-4

J. Herndon, S. Fleishman, A. Kornblith, M. Kosty, M. Green et al., Is quality of life predictive of the survival of patients with advanced nonsmall cell lung carcinoma?, Cancer, vol.74, issue.2, pp.333-340, 1999.
DOI : 10.1002/1097-0142(19940801)74:3<907::AID-CNCR2820740318>3.0.CO;2-#

A. P. Contandriopoulos, L'évaluation dans le domaine de la santé, 1991.

M. Demarteau, Evaluer: une question d'éthique. La Santé de l, homme, vol.345, pp.36-38, 2000.

D. Sicard, Ethique et Evaluation en Santé In: L'évaluation en santé. De la pratique aux résultats. Flammarion ed, pp.32-34, 2007.

D. Eddy, Variations in physician practice: the role of uncertainty, Health Affairs, vol.3, issue.2, pp.74-89, 1984.
DOI : 10.1377/hlthaff.3.2.74

J. Wennberg and G. , Small Area Variations in Health Care Delivery: A population-based health information system can guide planning and regulatory decision-making, Science, vol.182, issue.4117, pp.1102-1108, 1973.
DOI : 10.1126/science.182.4117.1102

G. Bordage, La prise de d??cision en m??decine??: quelques m??canismes mentaux et des conseils pratiques, La Revue de M??decine Interne, vol.26, issue.1, pp.14-17, 2005.
DOI : 10.1016/j.revmed.2005.04.012

J. Kassirer, Diagnostic Reasoning, Annals of Internal Medicine, vol.110, issue.11, pp.893-900, 1989.
DOI : 10.7326/0003-4819-110-11-893

A. Moskowitz, B. Kuipers, and J. Kassirer, Dealing with Uncertainty, Risks, and Tradeoffs in Clinical Decisions, Annals of Internal Medicine, vol.108, issue.3, pp.435-449, 1988.
DOI : 10.7326/0003-4819-108-3-435

J. Sackett, R. Haynes, and G. Guyatt, Clinical epidemiology: a basic science for clinical medicine, 1991.

W. Richardson, Diagnostic basé sur des faits prouvés : accroître le niveau d'exigence, EBM Journal (édition française), vol.10, issue.5, pp.7-8, 1998.

G. Diamond, J. Forrester, and . Metadiagnosis, Metadiagnosis, The American Journal of Medicine, vol.75, issue.1, pp.129-137, 1983.
DOI : 10.1016/0002-9343(83)91176-2

J. Hoc and R. Amalberti, Diagnostic et prise de décision dans les situations dynamiques, Psychologie Française, vol.39, issue.2, pp.177-192, 1994.

A. Audet, S. Greenfield, and M. Field, Medical Practice Guidelines: Current Activities and Future Directions, Annals of Internal Medicine, vol.113, issue.9, pp.709-714, 1990.
DOI : 10.7326/0003-4819-113-9-709

Y. Matillon and P. Durieux, De l'évaluation à la qualité en médecine. Aspects historiques. In: L'évaluation en santé. De la pratique aux résultats, pp.3-10, 2007.

C. Evin and . La, Place des usagers dans l'évaluation en santé In: L'évaluation en santé. De la pratiques aux résultats, pp.24-26, 2007.

S. Standards, options, recommandations: utilisation de la tomographie par émission de positons au 18FDG en cancérologie, Bull Cancer, pp.23-41, 2003.

J. Fletcher, E. Adams, K. Flynn, and F. Papatheofanis, Design of Prospective Clinical Trials for Assessment of PET, Clinical Positron Imaging, vol.1, issue.3, pp.201-211, 1998.
DOI : 10.1016/S1095-0397(98)00016-8

G. Laking, P. Price, and M. Sculpher, Assessment of the technology for functional imaging in cancer, European Journal of Cancer, vol.38, issue.16, pp.2194-2199, 2002.
DOI : 10.1016/S0959-8049(02)00385-4

J. Sunshine and K. Applegate, Technology Assessment for Radiologists, Radiology, vol.230, issue.2, pp.309-314, 2004.
DOI : 10.1148/radiol.2302031277

F. Girard, F. Empereur, F. Guillemin, and S. Briaçon, Recherche clinique, évaluation et qualité, Thérapie, vol.53, pp.559-563, 1998.

S. Briançon, F. Girard, F. Empereur, and F. Guillemin, Evaluation des pratiques professionnelles, Rev Epidemiol Sante Publique, vol.48, pp.541-550, 2000.

J. Bouyer, D. Hémon, S. Cordier, F. Derriennic, I. Stücker et al., Evaluation des actions de santé, Epidémiologie. Principes et méthodes quantitatives. Les éditions INSERM ed, pp.424-437, 1995.

E. Peter and . Valk, Randomized Controlled Trials Are Not Appropriate for Imaging Technology Evaluation, The Journal of Nuclear Medicine, vol.41, issue.7, pp.1125-1126, 2000.

W. Cochran, The Planning of Observational Studies of Human Populations, Journal of the Royal Statistical Society. Series A (General), vol.128, issue.2, pp.134-155, 1965.
DOI : 10.2307/2344179

J. Grimshaw, M. Campbell, M. Eccles, and N. Steen, Experimental and quasi-experimental designs for evaluating guideline implementation strategies, Family Practice, vol.17, issue.90001, pp.11-16, 2000.
DOI : 10.1093/fampra/17.suppl_1.S11

R. Groenwold, A. Hoes, and E. Hak, Confounding in publications of observational intervention studies, European Journal of Epidemiology, vol.15, issue.27, pp.413-415, 2007.
DOI : 10.3310/hta7270

C. Mann, Observational research methods. Research design II: cohort, cross sectional, and case-control studies, Emergency Medicine Journal, vol.20, issue.1, pp.54-60, 2003.
DOI : 10.1136/emj.20.1.54

R. Windsor, T. Baranowski, N. Clark, and G. Cutter, Evaluating Program Effectiveness In: Evaluation of Health Promotion, Health Education and Disease Prevention Programs, pp.145-150, 1994.

S. Guérin and C. Hill, Cancer epidemiology in France in 2010, comparison with the USA, Bull Cancer, vol.97, issue.1, pp.47-54, 2010.

D. Eilstein, Z. Uhry, L. Chérie-challine, J. Bloch, and H. Isnard, Mortalité par cancer du poumon en France métropolitaine Analyse de tendance et projection de, 1975.

F. Standards, Options et Recommandations: cancer bronchopulmonaire non à petites cellules, 2002.

K. Inoue, M. Sato, and S. Fujimura, Prognostic assessment of 1310 patients with non???small-cell lung cancer who underwent complete resection from 1980 to 1993, The Journal of Thoracic and Cardiovascular Surgery, vol.116, issue.3, pp.407-411, 1998.
DOI : 10.1016/S0022-5223(98)70006-6

J. Sisler, Delays in diagnosing cancer. Threat to the patient-physician relationship, Can Fam Physician, vol.49, pp.857-863, 2003.

M. Richards, A. Westcombe, S. Love, P. Littlejohns, and A. Ramirez, Influence of delay on survival in patients with breast cancer: a systematic review, The Lancet, vol.353, issue.9159, pp.1119-1126, 1999.
DOI : 10.1016/S0140-6736(99)02143-1

T. Risberg, S. Sorbye, J. Norum, and E. Wist, Diagnostic delay causes more psychological distress in female than in male cancer patients, Anticancer Res, vol.16, issue.2, pp.995-999, 1996.

G. Lillington, Management of solitary pulmonary nodules, Dis Mon, vol.37, issue.5, pp.271-318, 1991.

A. Jemal, T. Murray, A. Samuels, A. Ghafoor, E. Ward et al., Cancer Statistics, 2003, Cancer statistics, pp.5-26, 2003.
DOI : 10.3322/canjclin.53.1.5

C. Henschke, D. Mccauley, D. Yankelevitz, D. Naidich, G. Mcguinness et al., Early lung cancer action project, Cancer, vol.19, issue.5, pp.99-105, 1999.
DOI : 10.1038/bjc.1965.32

S. Swensen, J. Jett, J. Sloan, D. Midthun, T. Hartman et al., Screening for Lung Cancer with Low-Dose Spiral Computed Tomography, American Journal of Respiratory and Critical Care Medicine, vol.64, issue.4, pp.508-513, 2002.
DOI : 10.1359/jbmr.1997.12.11.1954

D. Ost and A. Fein, Evaluation and Management of the Solitary Pulmonary Nodule, American Journal of Respiratory and Critical Care Medicine, vol.134, issue.3, pp.782-787, 2000.
DOI : 10.1378/chest.112.6.1480

J. Rubins and H. Rubins, Temporal Trends in the Prevalence of Malignancy in Resected Solitary Pulmonary Lesions, Chest, vol.109, issue.1, pp.100-103, 1996.
DOI : 10.1378/chest.109.1.100

J. Gurney, Determining the likelihood of malignancy in solitary pulmonary nodules with Bayesian analysis. Part I. Theory., Radiology, vol.186, issue.2, pp.405-413, 1993.
DOI : 10.1148/radiology.186.2.8421743

D. Yankelevitz, Letter from the guest editor, Seminars in Ultrasound, CT and MRI, vol.21, issue.2, pp.95-96, 2000.
DOI : 10.1016/S0887-2171(00)90016-7

J. Erasmus, J. Connolly, H. Mcadams, and V. Roggli, Solitary Pulmonary Nodules: Part I. Morphologic Evaluation for Differentiation of Benign and Malignant Lesions, RadioGraphics, vol.20, issue.1, pp.43-58, 2000.
DOI : 10.1148/radiographics.20.1.g00ja0343

G. Higgins, T. Shields, and R. Keehn, The Solitary Pulmonary Nodule, Archives of Surgery, vol.110, issue.5, pp.570-575, 1975.
DOI : 10.1001/archsurg.1975.01360110116019

G. Lillington and C. Caskey, Evaluation and management of solitary and multiple pulmonary nodules, Clin Chest Med, vol.14, issue.1, pp.111-119, 1993.

S. Siegelman, N. Khouri, and F. Leo, Solitary pulmonary nodules: CT assessment., Radiology, vol.160, issue.2, pp.307-312, 1986.
DOI : 10.1148/radiology.160.2.3726105

R. Viggiano, S. Swensen, E. Rosenow, and I. , Evaluation and management of solitary and multiple pulmonary nodules, Clin Chest Med, vol.13, issue.1, pp.83-95, 1992.

E. Zerhouni, F. Stitik, S. Siegelman, D. Naidich, S. Sagel et al., CT of the pulmonary nodule: a cooperative study., Radiology, vol.160, issue.2, pp.319-327, 1986.
DOI : 10.1148/radiology.160.2.3726107

L. Garland, THE RATE OF GROWTH AND NATURAL DURATION OF PRIMARY BRONCHIAL CANCER, American Journal of Roentgenology, vol.96, issue.3, pp.604-611, 1966.
DOI : 10.2214/ajr.96.3.604

A. Tang, H. Moss, and R. Robertson, The solitary pulmonary nodule, European Journal of Radiology, vol.45, issue.1, pp.69-77, 2003.
DOI : 10.1016/S0720-048X(02)00297-8

D. Yankelevitz, A. Reeves, W. Kostis, B. Zhao, and C. Henschke, Small Pulmonary Nodules: Volumetrically Determined Growth Rates Based on CT Evaluation, Radiology, vol.217, issue.1, pp.251-256, 2000.
DOI : 10.1148/radiology.217.1.r00oc33251

M. Seemann, O. Seemann, W. Luboldt, H. Bonel, H. Sittek et al., Differentiation of malignant from benign solitary pulmonary lesions using chest radiography, spiral CT and HRCT, Lung Cancer, vol.29, issue.2, pp.105-124, 2000.
DOI : 10.1016/S0169-5002(00)00104-5

S. Swensen, M. Silverstein, D. Ilstrup, C. Schleck, and E. Edell, The probability of malignancy in solitary pulmonary nodules. Application to small radiologically indeterminate nodules, Archives of Internal Medicine, vol.157, issue.8, pp.849-855, 1997.
DOI : 10.1001/archinte.157.8.849

S. Swensen, R. Viggiano, D. Midthun, N. Muller, A. Sherrick et al., Lung Nodule Enhancement at CT: Multicenter Study, Radiology, vol.214, issue.1, pp.73-80, 2000.
DOI : 10.1148/radiology.214.1.r00ja1473

D. Midthun, S. Swensen, and J. Jett, Approach to the Solitary Pulmonary Nodule, Mayo Clinic Proceedings, vol.68, issue.4, pp.378-385, 1993.
DOI : 10.1016/S0025-6196(12)60136-0

H. Sm, D. Re, R. Glaser-s, S. Ae, and . Jb, Solitary pulmonary nodules found in a community-wide chest roentgenographic survey; a fiveyear follow-up study, Am Rev Tuberc, vol.79, issue.4, pp.427-439, 1959.

B. Tan, K. Flaherty, E. Kazerooni, and M. Iannettoni, The Solitary Pulmonary Nodule*, Chest, vol.123, issue.1, pp.89-96, 2003.
DOI : 10.1378/chest.123.1_suppl.89S

C. Heyer, T. Kagel, S. Lemburg, J. Walter, J. De-zeeuw et al., Transbronchial Biopsy Guided by Low-Dose MDCT: A New Approach for Assessment of Solitary Pulmonary Nodules, American Journal of Roentgenology, vol.187, issue.4, pp.933-939, 2006.
DOI : 10.2214/AJR.05.0763

J. Welker, M. Alattar, and S. Gautam, Repeat needle biopsies combined with clinical observation are safe and accurate in the management of a solitary pulmonary nodule, Cancer, vol.37, issue.3, pp.599-607, 2005.
DOI : 10.1053/stcs.2002.33696

S. Heck, P. Blom, and A. Berstad, Accuracy and complications in computed tomography fluoroscopy-guided needle biopsies of lung masses, European Radiology, vol.121, issue.6, pp.1387-1392, 2006.
DOI : 10.1097/01.RVI.0000124951.24134.50

M. Khan, R. Straub, S. Moghaddam, A. Maataoui, J. Gurung et al., Variables affecting the risk of pneumothorax and intrapulmonal hemorrhage in CT-guided transthoracic biopsy, European Radiology, vol.214, issue.1, pp.1356-1363, 2008.
DOI : 10.1148/radiology.214.1.r00ja1473

K. Yeow, I. Su, K. Pan, P. Tsay, K. Lui et al., Risk Factors of Pneumothorax and Bleeding, Chest, vol.126, issue.3, pp.748-754, 2004.
DOI : 10.1378/chest.126.3.748

J. O. Prior, S. Schmidt, and A. Delaloye, Investigation et prise en charge du nodule pulmonaire solitaire dans un environnement multidisciplinaire, M??decine Nucl??aire, vol.31, issue.8, pp.380-387, 2007.
DOI : 10.1016/j.mednuc.2007.06.003

S. Kim, M. Allen-auerbach, J. Goldin, B. Fueger, M. Dahlbom et al., Accuracy of PET/CT in characterization of solitary pulmonary lesions, J Nucl Med, vol.48, issue.2, pp.214-220, 2007.

K. Kernstine, F. Grannis, J. Rotter, and A. , Is There a Role for PET in the Evaluation of Subcentimeter Pulmonary Nodules?, Seminars in Thoracic and Cardiovascular Surgery, vol.17, issue.2, pp.110-114, 2005.
DOI : 10.1053/j.semtcvs.2005.04.004

C. Daniels, V. Lowe, M. Aubry, M. Allen, and J. Jett, The Utility of Fluorodeoxyglucose Positron Emission Tomography in the Evaluation of Carcinoid Tumors Presenting as Pulmonary Nodules, Chest, vol.131, issue.1, pp.255-260, 2007.
DOI : 10.1378/chest.06-0711

N. Côté, Le Cancer du poumon non à petites cellules: d'hier à aujourd'hui, Pharmactuel, vol.35, issue.4, pp.161-169, 2002.

P. Hoffman, A. Mauer, and E. Vokes, Lung cancer, The Lancet, vol.355, issue.9202, pp.479-485, 2000.
DOI : 10.1016/S0140-6736(00)82038-3

J. Schiller, Current Standards of Care in Small-Cell and Non-Small-Cell Lung Cancer, Oncology, vol.61, issue.1, pp.3-13, 2001.
DOI : 10.1159/000055386

E. Felip, P. Garrido, J. Trigo, M. Lopez-brea, L. Paz-ares et al., SEOM guidelines for the management of non-small-cell lung cancer (NSCLC), Clinical and Translational Oncology, vol.26, issue.[Suppl2], pp.284-289, 2009.
DOI : 10.1007/s12094-009-0356-4

B. Park, O. Louie, and N. Altorki, STAGING AND THE SURGICAL MANAGEMENT OF LUNG CANCER, Radiologic Clinics of North America, vol.38, issue.3, pp.545-61, 2000.
DOI : 10.1016/S0033-8389(05)70184-6

D. Ihde, D. Pfister, and S. Baker, Clinical practice guidelines for for the treatment of unresectable non-small-cell lung cancer, J Clin Oncol, vol.15, issue.8, pp.2996-3018, 1997.

K. Pisters, Adjuvant and neoadjuvant therapy for early stage non-small cell lung cancer, Seminars in Oncology, vol.28, issue.4 14, pp.23-28, 2001.
DOI : 10.1016/S0093-7754(01)90056-9

T. Moore and N. Ready, Update in non-small cell lung cancer, Med Health R I, vol.85, issue.1, pp.7-9, 2002.

K. Pisters, R. Ginsberg, and D. Giroux, Induction chemotherapy before surgery for early-stage lung cancer: A novel approach, The Journal of Thoracic and Cardiovascular Surgery, vol.119, issue.3, pp.429-437, 2000.
DOI : 10.1016/S0022-5223(00)70120-6

R. Rosell, J. Gomez-codina, C. Camps, S. Javier, J. Maestre et al., Preresectional chemotherapy in stage IIIA non-small-cell lung cancer: a 7-year assessment of a randomized controlled trial, Lung Cancer, vol.26, issue.1, pp.7-14, 1999.
DOI : 10.1016/S0169-5002(99)00045-8

A. Roth, E. Atkinson, and F. Fossella, Long-term follow-up of patients enrolled in a randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer, Lung Cancer, vol.21, issue.1, pp.1-6, 1998.
DOI : 10.1016/S0169-5002(98)00046-4

P. Burguet, S. Brusco, and . Corone, Comprendre la TEP (Tomographie par Emission de Positons au 18FDG) en Cancérologie, 2004.

M. Gould, C. Maclean, W. Kuschner, C. Rydzak, and D. Owens, Accuracy of Positron Emission Tomography for Diagnosis of Pulmonary Nodules and Mass Lesions, JAMA, vol.285, issue.7, pp.914-924, 2001.
DOI : 10.1001/jama.285.7.914

F. Duhaylongsod, V. Lowe, E. Patz, J. Vaughn, A. Coleman et al., Lung tumor growth correlates with glucose metabolism measured by fluoride-18 fluorodeoxyglucose positron emission tomography, The Annals of Thoracic Surgery, vol.60, issue.5, pp.1348-1352, 1995.
DOI : 10.1016/0003-4975(95)00754-9

Y. Hashimoto, T. Tsujikawa, C. Kondo, M. Maki, M. Momose et al., Accuracy of PET for diagnosis of solid pulmonary lesions with 18F-FDG uptake below the standardized uptake value of 2.5, J Nucl Med, vol.47, issue.3, pp.426-431, 2006.

I. Buvat and S. Les-limites-du, Les limites du SUV, M??decine Nucl??aire, vol.31, issue.4, pp.165-172, 2007.
DOI : 10.1016/j.mednuc.2007.03.003

A. Kieninger, R. Welsh, P. Bendick, G. Zelenock, and G. Chmielewski, Positron-emission tomography as a prognostic tool for early-stage lung cancer, The American Journal of Surgery, vol.191, issue.3, pp.433-436, 2006.
DOI : 10.1016/j.amjsurg.2005.10.052

G. Herder, R. Golding, O. Hoekstra, E. Comans, G. Teule et al., The performance of( 18)F-fluorodeoxyglucose positron emission tomography in small solitary pulmonary nodules, Eur J Nucl Med Mol Imaging, vol.31, issue.9, pp.1231-1236, 2004.

B. Fischer, U. Lassen, J. Mortensen, S. Larsen, A. Loft et al., Preoperative Staging of Lung Cancer with Combined PET???CT, New England Journal of Medicine, vol.361, issue.1, pp.32-39, 2009.
DOI : 10.1056/NEJMoa0900043

H. Van-tinteren, O. Hoekstra, E. Smit, J. Van-den-bergh, A. Schreurs et al., Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer: the PLUS multicentre randomised trial, The Lancet, vol.359, issue.9315, pp.1388-1393, 2002.
DOI : 10.1016/S0140-6736(02)08352-6

D. Maziak, G. Darling, R. Inculet, K. Gulenchyn, A. Driedger et al., Positron Emission Tomography in Staging Early Lung Cancer, Annals of Internal Medicine, vol.151, issue.4, pp.221-248, 2009.
DOI : 10.7326/0003-4819-151-4-200908180-00132

H. Steinert, M. Hauser, F. Allemann, H. Engel, T. Berthold et al., Non-small cell lung cancer: nodal staging with FDG PET versus CT with correlative lymph node mapping and sampling., Radiology, vol.202, issue.2, pp.441-446, 1997.
DOI : 10.1148/radiology.202.2.9015071

J. Maublant, J. Vuillez, and J. Talbot, Tomographie par émission de positons (TEP) et [F-18]-fluorodésoxyglucose (FDG) en cancérologie, Bull Cancer, vol.85, issue.11, pp.935-950, 1998.

D. Groheux, E. Hindie, J. Tredaniel, A. Giraudet, F. Vaylet et al., TEP-TDM pour l???exploration du nodule pulmonaire solitaire??: acquis et perspectives, Revue des Maladies Respiratoires, vol.26, issue.10, pp.1041-1055, 2009.
DOI : 10.1016/S0761-8425(09)73531-4

A. Bryant and R. Cerfolio, The Maximum Standardized Uptake Values on Integrated FDG-PET/CT Is Useful in Differentiating Benign From Malignant Pulmonary Nodules, The Annals of Thoracic Surgery, vol.82, issue.3, pp.1016-1020, 2006.
DOI : 10.1016/j.athoracsur.2006.03.095

S. Hamblen and V. Lowe, Clinical 18F-FDG oncology patient preparation techniques, J Nucl Med Technol, vol.31, issue.1, pp.3-7, 2003.

B. Line and C. White, Positron emission tomography scanning for the diagnosis and management of lung cancer, Current Treatment Options in Oncology, vol.54, issue.1, pp.63-73, 2004.
DOI : 10.1148/radiology.202.2.9015071

S. Stroobants, D. Hoore, I. Dooms, C. , D. Leyn et al., Additional Value of Whole-Body Fluorodeoxyglucose Positron Emission Tomography in the Detection of Distant Metastases of Non???Small-Cell Lung Cancer, Clinical Lung Cancer, vol.4, issue.4, pp.242-247, 2003.
DOI : 10.3816/CLC.2003.n.005

R. Coleman, PET in lung cancer, J Nucl Med, vol.40, issue.5, pp.814-820, 1999.

N. Khouri, M. Meziane, E. Zerhouni, E. Fishman, and S. Siegelman, The Solitary Pulmonary Nodule, Chest, vol.91, issue.1, pp.128-133, 1987.
DOI : 10.1378/chest.91.1.128

S. Swensen, J. Jett, W. Payne, R. Viggiano, P. Pairolero et al., An Integrated Approach to Evaluation of the Solitary Pulmonary Nodule, Mayo Clinic Proceedings, vol.65, issue.2, pp.173-186, 1990.
DOI : 10.1016/S0025-6196(12)65012-5

B. Fischer, J. Mortensen, and L. Hojgaard, Positron emission tomography in the diagnosis and staging of lung cancer: a systematic, quantitative review, The Lancet Oncology, vol.2, issue.11, pp.659-666, 2001.
DOI : 10.1016/S1470-2045(01)00555-1

J. Fletcher, B. Djulbegovic, H. Soares, B. Siegel, V. Lowe et al., Recommendations on the Use of 18F-FDG PET in Oncology, Journal of Nuclear Medicine, vol.49, issue.3, pp.480-508, 2008.
DOI : 10.2967/jnumed.107.047787

R. Rami-porta, J. Crowley, and P. Goldstraw, The revised TNM staging system for lung cancer, Ann Thorac Cardiovasc Surg, vol.15, issue.1, pp.4-9, 2009.

S. Balogova, D. Grahek, and K. Kerrou, L'imagerie nucléaire au 18FDGdans les lésions pleurales en apparences isolées, Rev Pneumol Clin, vol.59, pp.375-388, 2003.

F. Benard, D. Sterman, R. Smith, L. Kaiser, S. Albelda et al., Metabolic Imaging of Malignant Pleural Mesothelioma With Fluorodeoxyglucose Positron Emission Tomography, Chest, vol.114, issue.3, pp.713-722, 1998.
DOI : 10.1378/chest.114.3.713

T. Bury, P. Paulus, A. Dowlati, J. Corhay, P. Rigo et al., Evaluation of pleural diseases with FDG-PET imaging: preliminary report, Thorax, vol.52, issue.2, pp.187-189, 1997.
DOI : 10.1136/thx.52.2.187

K. Miles, Cancer imaging: is it cost-effective?, Cancer Imaging, vol.4, issue.2, pp.97-103, 2004.
DOI : 10.1102/1470-7330.2004.0017

K. Kernstine, K. Mclaughlin, Y. Menda, N. Rossi, D. Kahn et al., Can FDG-PET reduce the need for mediastinoscopy in potentially resectable nonsmall cell lung cancer?, The Annals of Thoracic Surgery, vol.73, issue.2, pp.394-401, 2002.
DOI : 10.1016/S0003-4975(01)03432-4

J. Vansteenkiste, S. Stroobants, D. Leyn, P. Dupont, P. Verschakelen et al., Mediastinal Lymph Node Staging With FDG-PET Scan in Patients With Potentially Operable Non-small Cell Lung Cancer, Chest, vol.112, issue.6, pp.1480-1486, 1997.
DOI : 10.1378/chest.112.6.1480

E. Christensen, T. Harvald, and M. Jendresen, The impact of delayed diagnosis of lung cancer on the stage at the time of operation, European Journal of Cardio-Thoracic Surgery, vol.107, issue.20, pp.880-884, 1997.
DOI : 10.1378/chest.107.6_Supplement.270S

A. Jensen, J. Mainz, and J. Overgaard, Impact of Delay on Diagnosis and Treatment of Primary Lung Cancer, Acta Oncologica, vol.51, issue.5, pp.147-152, 2002.
DOI : 10.1136/thx.51.12.1262

E. Robinson, J. Mohilever, J. Zidan, and D. Sapir, Delay in diagnosis of cancer. Possible effects on the stage of disease and survival, Cancer, vol.40, issue.7, pp.1454-1460, 1984.
DOI : 10.1016/S0025-7125(16)35623-1

C. Sanders, M. Egger, J. Donovan, D. Tallon, and S. Frankel, Reporting on quality of life in randomised controlled trials: bibliographic study, BMJ, vol.317, issue.7167, pp.1191-1194, 1998.
DOI : 10.1136/bmj.317.7167.1191

C. Moinpour, Measuring quality of life: an emerging science, Semin Oncol, vol.21, issue.5, pp.48-60, 1994.

B. Gandek, J. Ware, J. Aaronson, N. Alonso, J. Apolone et al., Tests of Data Quality, Scaling Assumptions, and Reliability of the SF-36 in Eleven Countries, Journal of Clinical Epidemiology, vol.51, issue.11, pp.1149-1158, 1998.
DOI : 10.1016/S0895-4356(98)00106-1

C. Mchorney, J. Ware, J. Raczek, and A. , The MOS 36-Item Short-Form Health Survey (SF-36), Medical Care, vol.31, issue.3, pp.247-263, 1993.
DOI : 10.1097/00005650-199303000-00006

C. Mchorney, J. Ware, J. Lu, J. Sherbourne, and C. , The MOS 36-Item Short-Form Health Survey (SF-36), Medical Care, vol.31, issue.3, pp.40-66, 1994.
DOI : 10.1097/00005650-199303000-00006

J. Ware, Measuring patients' views: the optimum outcome measure., BMJ, vol.306, issue.6890, pp.1429-1430, 1993.
DOI : 10.1136/bmj.306.6890.1429

J. Ware, J. Sherbourne, and C. , The MOS 36-ltem Short-Form Health Survey (SF-36), Medical Care, vol.30, issue.6, pp.473-483, 1992.
DOI : 10.1097/00005650-199206000-00002

N. Aaronson, S. Ahmedzai, and B. Bergman, The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology, JNCI Journal of the National Cancer Institute, vol.85, issue.5, pp.365-376, 1993.
DOI : 10.1093/jnci/85.5.365

G. Apolone, A. Filiberti, S. Cifani, R. Ruggiata, and P. Mosconi, Evaluation of the EORTC QLQ-C30 questionnaire: A comparison with SF-36 Health Survey in a cohort of Italian long-survival cancer patients, Annals of Oncology, vol.9, issue.5, pp.549-557, 1998.
DOI : 10.1023/A:1008264412398

M. Frost, A. Bonomi, C. Ferrans, G. Wong, and R. Hays, Patient, clinician, and population perspectives on determining the clinical significance of quality-of-life scores

J. Sloan, M. Frost, R. Berzon, A. Dueck, G. Guyatt et al., The clinical significance of quality of life assessments in oncology: a summary for clinicians, Supportive Care in Cancer, vol.37, issue.10, pp.988-998, 2006.
DOI : 10.1136/bmj.311.7010.899

T. Symonds, R. Berzon, P. Marquis, and T. Rummans, The Clinical Significance of Quality-of-Life Results: Practical Considerations for Specific Audiences, Mayo Clinic Proceedings, vol.77, issue.6, pp.572-583, 2002.
DOI : 10.4065/77.6.572

E. Cortesi, P. Gascon, D. Henry, T. Littlewood, R. Milroy et al., Standard of Care for Cancer-Related Anemia: Improving Hemoglobin Levels and Quality of Life, Oncology, vol.16, issue.1, pp.22-32, 2005.
DOI : 10.1634/theoncologist.7-2-126

G. Buccheri, D. Ferrigno, M. Tamburini, and C. Brunelli, The patient's perception of his own quality of life might have an adjunctive prognostic significance in lung cancer, Lung Cancer, vol.12, issue.1-2, pp.45-58, 1995.
DOI : 10.1016/0169-5002(94)00392-Z

R. Fielding and W. Wong, Quality of life as a predictor of cancer survival among Chinese liver and lung cancer patients, European Journal of Cancer, vol.43, issue.11, pp.1723-1730, 2007.
DOI : 10.1016/j.ejca.2007.05.002

P. Ganz, J. Lee, and J. Siau, Quality of life assessment. An independent prognostic variable for survival in lung cancer, Cancer, vol.318, issue.12, pp.3131-3135, 1991.
DOI : 10.1002/1097-0142(19910615)67:12<3131::AID-CNCR2820671232>3.0.CO;2-4

A. Justice, L. Aiken, H. Smith, and B. Turner, The role of functional status in predicting inpatient mortality with AIDS: A comparison with current predictors, Journal of Clinical Epidemiology, vol.49, issue.2, pp.193-201, 1996.
DOI : 10.1016/0895-4356(95)00546-3

M. Tamburini, C. Brunelli, S. Rosso, and V. Ventafridda, Prognostic value of quality of life scores in terminal cancer patients, Journal of Pain and Symptom Management, vol.11, issue.1, pp.32-41, 1996.
DOI : 10.1016/0885-3924(95)00135-2

D. Osoba, G. Rodrigues, J. Myles, B. Zee, and J. Pater, Interpreting the significance of changes in health-related quality-of-life scores., Journal of Clinical Oncology, vol.16, issue.1, pp.139-144, 1998.
DOI : 10.1200/JCO.1998.16.1.139

J. Blazeby, S. Brookes, and D. Alderson, The prognostic value of quality of life scores during treatment for oesophageal cancer, Gut, vol.49, issue.2, pp.227-230, 2001.
DOI : 10.1136/gut.49.2.227

V. Chiarion-sileni, D. Bianco, P. , D. Salvo, G. Lo et al., Quality of life evaluation in a randomised trial of chemotherapy versus bio-chemotherapy in advanced melanoma patients, European Journal of Cancer, vol.39, issue.11, pp.1577-1585, 2003.
DOI : 10.1016/S0959-8049(03)00372-1

M. Jerkeman, P. Aman, E. Cavallin-stahl, E. Torlakovic, M. Akerman et al., Prognostic implications of BCL6 rearrangement in uniformly treated patients with diffuse large B-cell lymphoma - a Nordic Lymphoma Group study, International Journal of Oncology, vol.20, issue.1, pp.161-165, 2002.
DOI : 10.3892/ijo.20.1.161

G. Ringdal, K. Gotestam, S. Kaasa, S. Kvinnsland, and K. Ringdal, Prognostic factors and survival in a heterogeneous sample of cancer patients, British Journal of Cancer, vol.73, issue.12, pp.1594-1599, 1996.
DOI : 10.1038/bjc.1996.300

R. Schmitt, Quality of life issues in lung cancer. New symptom management strategies, Chest, vol.103, issue.1, pp.51-55, 1993.
DOI : 10.1378/chest.103.1.51S

B. Balduyck, J. Hendriks, P. Lauwers, V. Schil, and P. , Quality of life evolution after lung cancer surgery: A prospective study in 100 patients, Lung Cancer, vol.56, issue.3, pp.423-431, 2007.
DOI : 10.1016/j.lungcan.2007.01.013

A. Mohan, P. Singh, S. Singh, A. Goyal, A. Pathak et al., Quality of life in lung cancer patients: impact of baseline clinical profile and respiratory status, European Journal of Cancer Care, vol.23, issue.3, pp.268-276, 2007.
DOI : 10.1016/S0167-8140(00)00252-8

M. Helsing, B. Bergman, L. Thaning, and U. Hero, Quality of life and survival in patients with advanced non-small cell lung cancer receiving supportive care plus chemotherapy with carboplatin and etoposide or supportive care only. A multicentre randomised phase III trial, European Journal of Cancer, vol.34, issue.7, pp.1036-1044, 1998.
DOI : 10.1016/S0959-8049(97)10122-8

P. Ganz, R. Figlin, C. Haskell, L. Soto, N. Siau et al., Supportive care versus supportive care and combination chemotherapy in metastatic non-small cell lung cancer. Does chemotherapy make a difference?, Cancer, vol.317, issue.7, pp.1271-1278, 1989.
DOI : 10.7326/0003-4819-95-4-414

M. Cerf and N. , Survie attendue des patients atteints de cancers en France : Etat des lieux, 2010.

R. Giorgi, A. Armanet, J. Gouvernet, P. Bonnier, and M. Fieschi, Revue comparative des mod??les r??gressifs de survie brute et de survie relative, Revue d'??pid??miologie et de Sant?? Publique, vol.53, issue.4, pp.409-417, 2005.
DOI : 10.1016/S0398-7620(05)84623-1

F. Molinié, A. Danzon, G. Hédelin, A. Sauleau, and . Poumon, In: Survie des patients atteints de cancer en France, Etudes des registres du réseau FRANCIM, pp.185-192, 2007.

J. Pfannschmidt, T. Muley, H. Bulzebruck, H. Hoffmann, and H. Dienemann, Prognostic assessment after surgical resection for non-small cell lung cancer: Experiences in 2083 patients, Lung Cancer, vol.55, issue.3, pp.371-377, 2007.
DOI : 10.1016/j.lungcan.2006.10.017

L. Tanoue and F. Detterbeck, New TNM classification for non-small-cell lung cancer, Expert Review of Anticancer Therapy, vol.356, issue.4, pp.413-423, 2009.
DOI : 10.1056/NEJMoa060467

C. Chouaid, Critères d'évaluation des cancers broncho-pulmonaires. Quels critères économiques ?, Rev Mal Respir, vol.23, pp.16-118, 2006.

C. Lejeune, K. Alzahouri, M. Woronoff-lemsi, P. Arveux, A. Bernard et al., Use of a decision analysis model to assess the medicoeconomic implications of FDG PET imaging in diagnosing a solitary pulmonary nodule, The European Journal of Health Economics, vol.12, issue.3, pp.203-214, 2005.
DOI : 10.7326/0003-4819-138-9-200305060-00009

M. Ruoh-fang-yen, T. Yen, and . Hsiu-hsi-chen, The Cost-utility Analysis of 18-Fluoro-2-Deoxyglucose Positron Emission Tomography in the Diagnosis of Recurrent Nasopharyngeal Carcinoma, Acad Radiol, vol.16, pp.54-60, 2009.

P. Valk, T. Pounds, D. Hopkins, M. Haseman, G. Hofer et al., Staging non???small cell lung cancer by whole-body positron emission tomographic imaging, The Annals of Thoracic Surgery, vol.60, issue.6, pp.1573-1581, 1995.
DOI : 10.1016/0003-4975(95)00752-0

J. Daures and G. Delande, L'évaluation médico-économique: objectifs, méthodologie, limites, Gastroenterol Clin Biol, vol.24, pp.1029-1031, 2000.

K. Alzahouri, M. Velten, P. Arveux, M. Woronoff-lemsi, D. Jolly et al., Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts, BMC Cancer, vol.138, issue.1, p.93, 2008.
DOI : 10.7326/0003-4819-138-9-200305060-00009

C. Mathers and D. Loncar, Projections of Global Mortality and Burden of Disease from 2002 to 2030, PLoS Medicine, vol.52, issue.11, p.442, 2002.
DOI : 10.1371/journal.pmed.0030442.st007

F. Kamangar, G. Dores, and W. Anderson, Patterns of Cancer Incidence, Mortality, and Prevalence Across Five Continents: Defining Priorities to Reduce Cancer Disparities in Different Geographic Regions of the World, Journal of Clinical Oncology, vol.24, issue.14, pp.2137-2150, 2006.
DOI : 10.1200/JCO.2005.05.2308

A. Belot, P. Grosclaude, N. Bossard, E. Jougla, E. Benhamou et al., Cancer incidence and mortality in France over the period 1980???2005, Revue d'??pid??miologie et de Sant?? Publique, vol.56, issue.3, pp.159-175, 1980.
DOI : 10.1016/j.respe.2008.03.117

URL : https://hal.archives-ouvertes.fr/hal-00538673

C. Gridelli, F. Perrone, F. Nelli, F. Marinis, and . De, Quality of life in lung cancer patients, Annals of Oncology, vol.12, issue.suppl 3, pp.21-25, 2001.
DOI : 10.1093/annonc/12.suppl_3.S21

H. Vesselle, J. Freeman, L. Wiens, J. Stern, H. Nguyen et al., Fluorodeoxyglucose Uptake of Primary Non-Small Cell Lung Cancer at Positron Emission Tomography: New Contrary Data on Prognostic Role, Clinical Cancer Research, vol.13, issue.11, pp.3255-3263, 2007.
DOI : 10.1158/1078-0432.CCR-06-1128

N. Bossard, M. Velten, and L. Remontet, Surveillances des cancers en France: Etats des lieux et perspectives en, Bulletin épidémiologie hebdomadaire, vol.9, issue.10, pp.65-84, 2007.

A. Krupnick, D. Kreisel, A. Hope, J. Bradley, R. Govindan et al., Recent Advances and Future Perspectives in the Management of Lung Cancer, Current Problems in Surgery, vol.42, issue.8, pp.540-610, 2005.
DOI : 10.1067/j.cpsurg.2005.05.002

J. Molina, P. Yang, S. Cassivi, S. Schild, and A. Adjei, Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship, Mayo Clinic Proceedings, vol.83, issue.5, pp.584-594, 2008.
DOI : 10.1016/S0025-6196(11)60735-0

C. Dujon, R. Azarian, and P. Petitpretz, Longs survivants de cancers bronchiques non ?? petites cellules stades IIIB-IV. Caract??ristiques et facteurs pronostiques ?? partir d???une s??rie r??trospective, Revue des Maladies Respiratoires, vol.26, issue.9, pp.952-960, 2009.
DOI : 10.1016/S0761-8425(09)73330-3

J. Dancey, F. Shepherd, R. Gralla, and Y. Kim, Quality of life assessment of second-line docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy: results of a prospective, randomized phase III trial, Lung Cancer, vol.43, issue.2, pp.183-194, 2004.
DOI : 10.1016/j.lungcan.2003.09.001

T. Aoki, M. Tsuchida, T. Hashimoto, M. Saito, T. Koike et al., Quality of Life after Lung Cancer Surgery: Video-Assisted Thoracic Surgery versus Thoracotomy, Heart, Lung and Circulation, vol.16, issue.4, pp.285-289, 2007.
DOI : 10.1016/j.hlc.2007.02.081

C. Belani, J. Pereira, J. Von-pawel, A. Pluzanska, V. Gorbounova et al., Effect of chemotherapy for advanced non-small cell lung cancer on patients??? quality of life, Lung Cancer, vol.53, issue.2, pp.231-239, 2006.
DOI : 10.1016/j.lungcan.2006.05.003

J. Bloom, D. Petersen, and S. Kang, Multi-dimensional quality of life among long-term (5+ years) adult cancer survivors, Psycho-Oncology, vol.13, issue.8, pp.691-706, 2007.
DOI : 10.1093/jnci/94.1.39

H. Bozcuk, B. Dalmis, M. Samur, M. Ozdogan, M. Artac et al., Quality of Life in Patients With Advanced Non-Small Cell Lung Cancer, Cancer Nursing, vol.29, issue.2, pp.104-110, 2006.
DOI : 10.1097/00002820-200603000-00004

A. Mohan, C. Mohan, M. Bhutani, A. Pathak, H. Pal et al., Quality of life in newly diagnosed patients with lung cancer in a developing country: is it important?, European Journal of Cancer Care, vol.19, issue.3, pp.293-298, 2006.
DOI : 10.1006/pmed.1999.0523

A. Leplege and S. Hunt, The Problem of Quality of Life in Medicine, JAMA: The Journal of the American Medical Association, vol.278, issue.1, pp.47-50, 1997.
DOI : 10.1001/jama.1997.03550010061041

D. Osoba, Lessons learned from measuring health-related quality of life in oncology., Journal of Clinical Oncology, vol.12, issue.3, pp.608-616, 1994.
DOI : 10.1200/JCO.1994.12.3.608

T. Young and J. Maher, Collecting quality of life data in EORTC clinical trials???what happens in practice?, Psycho-Oncology, vol.5, issue.3, pp.260-263, 1999.
DOI : 10.1007/BF00435963

J. Brazier, R. Harper, N. Jones, O. Cathain, A. Thomas et al., Validating the SF-36 health survey questionnaire: new outcome measure for primary care., BMJ, vol.305, issue.6846, pp.160-164, 1992.
DOI : 10.1136/bmj.305.6846.160

K. Van-steen, D. Curran, J. Kramer, G. Molenberghs, V. Vreckem et al., Multicollinearity in prognostic factor analyses using the EORTC QLQ-C30: identification and impact on model selection, Statistics in Medicine, vol.6, issue.24, pp.3865-3884, 2002.
DOI : 10.1023/A:1018491512095

D. Cox, Regression Models and Life-Tables, J Royal Stat Soc, vol.4, pp.187-220, 1972.
DOI : 10.1007/978-1-4612-4380-9_37

D. Hosmer, S. Lemeshow, and S. May, Assessment of Model Adequacy Applied Survival Analysis. Regression Modeling of Tine-to-Event Data, pp.169-206, 2008.

E. Lee and O. Go, SURVIVAL ANALYSIS IN PUBLIC HEALTH RESEARCH, Annual Review of Public Health, vol.18, issue.1, pp.105-134, 1997.
DOI : 10.1146/annurev.publhealth.18.1.105

J. Brown, H. Thorpe, V. Napp, D. Fairlamb, N. Gower et al., Assessment of Quality of Life in the Supportive Care Setting of the Big Lung Trial in Non???Small-Cell Lung Cancer, Journal of Clinical Oncology, vol.23, issue.30, pp.7417-7427, 2005.
DOI : 10.1200/JCO.2005.09.158

A. Montazeri, R. Milroy, D. Hole, J. Mcewen, and C. Gillis, Quality of life in lung cancer patients: as an important prognostic factor, Lung Cancer, vol.31, pp.2-3, 2001.

J. Sculier, J. Lafitte, M. Paesmans, J. Lecomte, C. Alexopoulos et al., Chemotherapy improves low performance status lung cancer patients, European Respiratory Journal, vol.30, issue.6, pp.1186-1192, 2007.
DOI : 10.1183/09031936.00034507

L. Derogatis, M. Abeloff, and N. Melisaratos, Psychological Coping Mechanisms and Survival Time in Metastatic Breast Cancer, JAMA: The Journal of the American Medical Association, vol.242, issue.14, pp.1504-1508, 1979.
DOI : 10.1001/jama.1979.03300140020016

E. Frick, M. Tyroller, and M. Panzer, Anxiety, depression and quality of life of cancer patients undergoing radiation therapy: a cross-sectional study in a community hospital outpatient centre, European Journal of Cancer Care, vol.67, issue.2, pp.130-136, 2007.
DOI : 10.1002/1097-0142(20000815)89:4<873::AID-CNCR21>3.0.CO;2-K

A. Bottomley and F. Efficace, Predicting survival in advanced cancer patients: is it possible with patient-reported health status data?, Annals of Oncology, vol.17, issue.7, pp.1037-1038, 2006.
DOI : 10.1093/annonc/mdl065

T. Conroy, A. Brédart, and S. Briançon, Valeur pronostique des mesures de qualité de vie en cancérologie, Rev Francoph Psycho-Oncologie, vol.1, pp.23-28, 2005.

E. Lemonnier, L'évaluation des technologies médicales, ADSP, vol.39, pp.28-33, 2002.

J. Leclère, L. Ollivier, S. Dolbeault, and S. Neuenschwander, Dialogue entre le radiologue et le patient atteint d???un cancer, Journal de Radiologie, vol.87, issue.2, pp.99-104, 2006.
DOI : 10.1016/S0221-0363(06)73978-6

K. Alzahouri, M. Velten, P. Arveux, M. Woronoff-lemsi, D. Jolly et al., Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts, BMC Cancer, vol.138, issue.1, p.93, 2008.
DOI : 10.7326/0003-4819-138-9-200305060-00009

C. Alzahouri, M. Lejeune, P. Woronoff-lemsi, F. Arveux, and . Guillemin, Clinical Costeffectiveness analysis of strategies introducing FDG-PET into the mediastinal staging of nonsmall-cell lung cancer from the French healthcare system perspective, Radiology, pp.60-479, 2005.

C. Bernard·, ·. Binquet, and . Francis-guillemin, Use of a decision analysis model to assess the medicoeconomic implications of FDG PET imaging in diagnosing a solitary pulmonary nodule, Eur J Health Econom, vol.50, pp.203-214, 2005.

P. Bey, M. Bedenne, M. Md-;-jean-faivre, M. Arveux, F. Guillemin et al., Use of a Decision Analysis Model to Assess the Cost-Effectiveness of 18F-FDG PET in the Management of Metachronous Liver Metastases of Colorectal Cancer

F. Guillemin, Does the Availability of Positron Emission Tomography modify Diagnostic Strategies for Solitary Pulmonary Nodules? An Observational Study in France, Publié: BMC Cancer, vol.9, p.139, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00475551

M. Lemsi, F. Velten, and . Guillemin, Solitary Pulmonary Nodule: consequences for patient quality of life, Publié: Quality of Life Research, vol.20, issue.1, pp.101-109, 2011.

K. Alzahouri, C. Lejeune, P. Arveux, M. Woronoff-lemsi, and F. Guillemin, Modélisation médicoéconomique de la caméra TEP en cas de lymphomeEvaluation en santé publique, 2002.

K. Alzahouri, C. Lejeune, M. Woronoff-lemsi, P. Arveux, and F. Guillemin, Analyse coût-efficacité de la tomographie par émission de positons pour le bilan d'extension médiastinale de cancer du poumon non à petites cellules. Revue d'Epidémiologie et de Santé Publique, pp.1-30, 2004.

K. Alzahouri, Y. Martinet, M. Velten, E. Quoix, M. Woronoff-lemsi et al., La prise en charge du nodule pulmonaire isolé en France : une cohorte prospective, 2005.

K. Alzahouri, M. Velten, M. Woronoff-lemsi, D. Jolly, P. Arveux et al., Les trajectoires de soins des patients ayant un nodule pulmonaire isolé : étude multicentrique dans 18 départements de l'inter-région Nord-Est, 2006.

I. Lemonnier, C. Baumann, N. Jay, K. Alzahouri, P. Arveux et al., La tomographie par émission de positon (TEP) modifie t-elle la prise en charge diagnostique du nodule pulmonaire isolé (NPI) ? 2 ième Conférence francophone d'épidémiologie clinique ADELF, pp.23-23, 2008.

I. Lemonnier, C. Baumann, N. Jay, K. Alzahouri, P. Arveux et al., La tomographie par émission de positon (TEP) modifie t-elle la prise en charge diagnostique du nodule pulmonaire isolé (NPI) ? 2 e Forum du Cancéropôle Grand Est, 2008.

I. Lemonnier, C. Baumann, F. Vitry, P. Arveux, D. Jolly et al., Nodule Pulmonaire Isolé (NPI) : Impact sur la qualité de vie (QV) des patients. 3 ième Conférence francophone d'épidémiologie clinique ADELF, 2009.

I. Lemonnier, C. Baumann, F. Vitry, P. Arveux, D. Jolly et al., Solitary pulmonary nodules: consequences for patient quality of life, ISOQOL 16th Annual Meeting, pp.28-31, 2009.
DOI : 10.1378/chest.123.1_suppl.89S