. Dans-ce-contexte, il nous est paru judicieux, d'étudier plus en avant la synthèse des Cglycosyl-?-amino acides, p.85

A. S. Norgren, M. Geitmann, H. U. Danielson, and P. I. Arvidsson, Biomolecular recognition of glycosylated ??3-peptides by GalNAc specific lectins, Journal of Molecular Recognition, vol.562, issue.2, pp.132-138, 2007.
DOI : 10.1615/CritRevOncog.v6.i1.50

G. L. Simpson and A. H. Gordon, Glycosylated Foldamers To Probe the Carbohydrate???Carbohydrate Interaction, Journal of the American Chemical Society, vol.128, issue.33, pp.10638-10639, 2006.
DOI : 10.1021/ja0614565

A. Dondoni, A. Massi, S. Sabbatini, and V. Bertolasi, Synthesis of C-glycosyl ??-amino acids by asymmetric Mannich-type three-component reactions, Tetrahedron Letters, vol.45, issue.11, pp.2381-2384, 2004.
DOI : 10.1016/j.tetlet.2004.01.070

C. Palomo and M. Oiarbide, -Linked Glyco ??-Amino Acids through a Stereoselective ???Acetate??? Mannich Reaction as the Key Strategic Element, Journal of the American Chemical Society, vol.124, issue.29, pp.8637-8643, 2002.
DOI : 10.1021/ja026250s

Y. Inaba, S. Yano, and Y. Mikata, Facile synthesis of 2-(??-C-glucopyranosyl)-??-amino acid: a new class of glycopeptide building block, Tetrahedron Letters, vol.48, issue.6, pp.993-997, 2007.
DOI : 10.1016/j.tetlet.2006.12.006

F. Fülöp, In studies in natural product chemistry, pp.273-306, 2000.

T. Sano and K. Kaya, Two new (E)-2-amino-2-butenoic acid (Dhb)-containing microcystins isolated from Oscillatoria agardhii, Tetrahedron, vol.54, issue.3-4, pp.463-470, 1998.
DOI : 10.1016/S0040-4020(97)10291-5

S. H. Gellman, Foldamers:?? A Manifesto, Accounts of Chemical Research, vol.31, issue.4, pp.173-180, 1998.
DOI : 10.1021/ar960298r

T. Raguse, L. Lai, and S. H. Gellman, Evidence that the -Peptide 14-Helix is Stabilized by 3-Residues with Side-Chain Branching Adjacent to the -Carbon Atom, Helvetica Chimica Acta, vol.85, issue.12, pp.4154-4164, 2002.
DOI : 10.1002/hlca.200290001

D. Seebach, B. Jaun, R. Sebesta, R. L. Mathad, O. Flogel et al., Synthesis, and Helix or Hairpin-Turn Secondary Structures of ???Mixed?????/??-Peptides Consisting of Residues with Proteinogenic Side Chains and of 2-Amino-2-methylpropanoic Acid (Aib), Helvetica Chimica Acta, vol.124, issue.9, pp.1801-1825, 2006.
DOI : 10.1055/s-1997-6117

Y. J. Chung, B. R. Huck, L. A. Christianson, H. E. Stanger, S. Krauthauser et al., Stereochemical Control of Hairpin Formation in ??-Peptides Containing Dinipecotic Acid Reverse Turn Segments, Journal of the American Chemical Society, vol.122, issue.17, pp.3995-4004, 2000.
DOI : 10.1021/ja993416p

Y. J. Chung, L. A. Christianson, H. E. Stanger, D. R. Powell, and S. H. Gellman, A ??-Peptide Reverse Turn that Promotes Hairpin Formation, Journal of the American Chemical Society, vol.120, issue.40, pp.10555-10556, 1998.
DOI : 10.1021/ja982249a

D. Seebach, S. Abele, T. Sifferlen, M. Hanggi, S. Gruner et al., Preparation and Structure of??-Peptides Consisting of Geminally Disubstituted??2,2- and??3,3-Amino Acids: A Turn Motif for??-Peptides, Helvetica Chimica Acta, vol.81, issue.12, pp.2218-2243, 1998.
DOI : 10.1002/(SICI)1522-2675(19981216)81:12<2218::AID-HLCA2218>3.0.CO;2-0

T. Heck, M. Limbach, B. Geueke, M. Zacharias, J. Gardiner et al., Enzymatic Degradation of??- and Mixed??,??-Oligopeptides, Chemistry & Biodiversity, vol.71, issue.12, pp.1325-1349, 2006.
DOI : 10.1002/cbdv.200690136

L. Fanuel, I. Thamm, V. Kostanjevecki, B. Samyn, B. Joris et al., Two new aminopeptidases from Ochrobactrum anthropi active on D-alanyl-p-nitroanilide, Cellular and Molecular Life Sciences CMLS, vol.55, issue.5, pp.812-823, 1999.
DOI : 10.1007/s000180050334

Y. Hamuro, J. P. Schneider, and W. F. Degrado, De Novo Design of Antibacterial ??-Peptides, Journal of the American Chemical Society, vol.121, issue.51, pp.12200-12201, 1999.
DOI : 10.1021/ja992728p

D. Liu and W. F. Degrado, De Novo Design, Synthesis, and Characterization of Antimicrobial ??-Peptides, Journal of the American Chemical Society, vol.123, issue.31, pp.7553-7559, 2001.
DOI : 10.1021/ja0107475

E. A. Porter, B. Weisblum, and S. H. Gellman, Mimicry of Host-Defense Peptides by Unnatural Oligomers:?? Antimicrobial ??-Peptides, Journal of the American Chemical Society, vol.124, issue.25, pp.7324-7330, 2002.
DOI : 10.1021/ja0260871

M. A. Schmitt, B. Weisblum, and S. H. Gellman, Unexpected Relationships between Structure and Function in ??,??-Peptides:?? Antimicrobial Foldamers with Heterogeneous Backbones, Journal of the American Chemical Society, vol.126, issue.22, pp.6848-6849, 2004.
DOI : 10.1021/ja048546z

K. Gademann, T. Kimmerlin, D. Hoyer, and D. Seebach, Peptide Folding Induces High and Selective Affinity of a Linear and Small ??-Peptide to the Human Somatostatin Receptor 4, Journal of Medicinal Chemistry, vol.44, issue.15, pp.2460-2468, 2001.
DOI : 10.1021/jm010816q

K. Gademann, M. Ernst, D. Hoyer, and D. Seebach, Synthesis and Biological Evaluation of a Cyclo--tetrapeptide as a Somatostatin Analogue, Angewandte Chemie International Edition, vol.38, issue.9, pp.1223-1225, 1999.
DOI : 10.1002/(SICI)1521-3773(19990503)38:9<1223::AID-ANIE1223>3.0.CO;2-A

K. Gademann, M. Ernst, and D. Seebach, The Cyclo-??-Tetrapeptide (??-HPhe-??-HThr-??-HLys-??-HTrp): Synthesis, NMR Structure in Methanol Solution, and Affinity for Human Somatostatin Receptors, Helvetica Chimica Acta, vol.83, issue.1, pp.16-23, 2000.
DOI : 10.1002/(SICI)1522-2675(20000119)83:1<16::AID-HLCA16>3.0.CO;2-3

S. Poenaru, J. R. Lamas, G. Folkers, and D. Seebach, )-3-Hydroxybutanoate and ??-Homoalanine Oligomers:?? Synthesis and Binding Affinity to a Class I Major Histocompatibility Complex Protein, Journal of Medicinal Chemistry, vol.42, issue.13, pp.2318-2331, 1999.
DOI : 10.1021/jm981123l

M. Liu and M. P. Sibi, Recent advances in the stereoselective synthesis of ??-amino acids, Tetrahedron, vol.58, issue.40, pp.7991-8035, 2002.
DOI : 10.1016/S0040-4020(02)00991-2

D. Seebach, A. K. Beck, and D. Bierbaum, The World of??- and??-Peptides Comprised of Homologated Proteinogenic Amino Acids and Other Components, Chemistry & Biodiversity, vol.1, issue.8, pp.1111-1239, 2004.
DOI : 10.1002/cbdv.200490087

P. W. Sutton, A. Bradley, J. Farras, P. Romea, F. Urpi et al., Pseudoaxially Disubstituted Cyclo-??3-tetrapeptide Scaffolds, Tetrahedron, vol.56, issue.40, pp.7947-7958, 2000.
DOI : 10.1016/S0040-4020(00)00666-9

W. Bachmann and W. Struve, The Arndt-Eister Synthesis, pp.38-62, 1942.

D. Seebach, M. Overhand, F. N. Künhle, B. Martinono, L. Oberer et al., ??-Peptides: Synthesis by Arndt-Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X-ray crystallography. Helical secondary structure of a ??-hexapeptide in solution and its stability towards pe, Helvetica Chimica Acta, vol.20, issue.4, pp.913-941, 1996.
DOI : 10.1002/anie.198102801

C. Yuan and R. M. Williams, Peptide Antibiotics TAN-1057A-D, Journal of the American Chemical Society, vol.119, issue.49, pp.11777-11784, 1997.
DOI : 10.1021/ja972670j

D. Seebach, L. Schaeffer, F. Gessier, P. Bindschädler, C. Jäger et al., Enantioselective Preparation of 2-Aminomethyl Carboxylic Acid Derivatives: Solving the 2-Amino Acid Problem with the Chiral Auxiliary 4-Isopropyl-5,5-diphenyloxazolidin-2-one (DIOZ). Preliminary Communication, Helvetica Chimica Acta, vol.86, issue.6, pp.1852-1861, 2003.
DOI : 10.1002/hlca.200390149

S. G. Davies and O. Ichihara, Asymmetric synthesis of a highly functionalized ??-amino acid: the key amino acid of sperabillins B and D, Tetrahedron Letters, vol.40, issue.52, pp.9313-9316, 1999.
DOI : 10.1016/S0040-4039(99)01954-1

E. Graf-von-roedern, E. Lohof, G. Hessler, M. Hoffmann, and H. Kessler, Synthesis and Conformational Analysis of Linear and Cyclic Peptides Containing Sugar Amino Acids, Journal of the American Chemical Society, vol.118, issue.42, pp.10156-10167, 1996.
DOI : 10.1021/ja961068a

J. A. Lord, J. Waterfield, X. Hughes, and H. W. Kosterlitz, Endogenous opioid peptides: multiple agonists and receptors, Nature, vol.17, issue.5611, pp.495-498, 2005.
DOI : 10.1111/j.1600-0773.1975.tb00837.x

B. Drouillat, B. Kellam, G. Dekany, M. S. Starr, and I. Toth, Solid phase synthesis of C-terminal carbohydrate modified enkephalins, Bioorganic & Medicinal Chemistry Letters, vol.7, issue.17, pp.2247-2250, 1997.
DOI : 10.1016/S0960-894X(97)00395-8

E. Oualid, F. Burm, M. Cohen, L. H. Van-boom, J. H. Van-den-elst et al., Design, Synthesis, and Evaluation of Su- gar Amino Acid Based Inhibitors of Pro- tein??Prenyl??Transferases??PFT??and??PGGT-1, Journal of Medicinal Chemistry, vol.47, issue.16, pp.3920-3923, 2004.
DOI : 10.1021/jm049927q

G. M. Grotenbreg, C. M. Timmers, A. L. Liamas-saiz, M. Verdoes, G. A. Van-der-marel et al., An Unusual Reverse Turn Structure Adopted by a Furanoid Sugar Amino Acid Incorporated in Gramicidin S, Journal of the American Chemical Society, vol.126, issue.11, pp.3444-3446, 2004.
DOI : 10.1021/ja0397254

K. C. Nicolaou, H. Florke, M. G. Egan, T. Barth, and V. A. Estevez, Carbonucleotoids and carbopeptoids: New carbohydrate oligomers, Tetrahedron Letters, vol.36, issue.11, pp.1775-1778, 1995.
DOI : 10.1016/0040-4039(95)00121-R

H. P. Wessel, C. Mitchell, C. M. Lobato, and G. Schmid, Saccharide???Peptide Hybrids as Novel Oligosaccharide Mimetics, Angewandte Chemie International Edition in English, vol.34, issue.2324, pp.2712-2716, 1995.
DOI : 10.1002/anie.199527121

R. A. Goodnow, A. Richou, and S. Tam, Synthesis of thymine, cytosine, adenine, and guanine containing N-Fmoc protected amino acids: Building blocks for construction of novel oligonucleotide backbone analogs, Tetrahedron Letters, vol.38, issue.18, pp.3195-3198, 1997.
DOI : 10.1016/S0040-4039(97)00610-2

R. A. Goodnow, S. Tam, D. L. Pruess, and W. W. Mccomas, Oligomer synthesis and DNA/RNA recognition properties of a novel oligonucleotide backbone analog: Glucopyranosyl nucleic amide (GNA), Tetrahedron Letters, vol.38, issue.18, pp.3199-3202, 1997.
DOI : 10.1016/S0040-4039(97)00611-4

C. M. Timmers, J. J. Turner, C. M. Ward, G. A. Van-der-marel, M. Kouwijzer et al., Synthesis and Biological Evaluation of a Backbone-Modified Phytoalexin Elicitor, Chemistry - A European Journal, vol.99, issue.6, pp.920-929, 1997.
DOI : 10.1016/0040-4039(95)01027-F

F. Sicherl and V. Wittmann, Orthogonally Protected Sugar Diamino Acids as Building Blocks for Linear and Branched Oligosaccharide Mimetics, Angewandte Chemie International Edition, vol.163, issue.14, pp.2096-2099, 2005.
DOI : 10.1002/anie.200462595

URL : https://kops.uni-konstanz.de/bitstream/123456789/9921/2/Sicherl_Orthogonally_supp_info_2005.pdf

A. Scaffidi, B. W. Skelton, R. V. Stick, and A. H. White, Amino Acids, Australian Journal of Chemistry, vol.57, issue.8, pp.733-740, 2004.
DOI : 10.1071/CH04014

T. D. Claridge, D. D. Long, N. L. Hungerford, R. T. Smith, M. D. Marquess et al., An octameric carbopeptoid; secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates, Tetrahedron Letters, vol.40, issue.11, pp.2199-2202, 1999.
DOI : 10.1016/S0040-4039(99)00111-2

T. D. Claridge, D. D. Long, C. M. Baker, B. Odell, G. H. Grant et al., Helix-Forming Carbohydrate Amino Acids, The Journal of Organic Chemistry, vol.70, issue.6, pp.2082-2090, 2005.
DOI : 10.1021/jo0480040

T. K. Chakraborty, P. Srinivasu, S. S. Madhavendra, S. Kiran-kumar, and A. C. Kunwar, Conformational studies of the linear homooligomers of a glucose-derived furanoid sugar amino acid, Tetrahedron Letters, vol.45, issue.18, pp.3573-3577, 2004.
DOI : 10.1016/j.tetlet.2004.03.048

T. K. Chakraborty, S. Jayaprakash, P. Srinivasu, S. S. Madhavendra, A. R. Sankar et al., Furanoid sugar amino acid based peptidomimetics: well-defined solution conformations to gel-like structures, Tetrahedron, vol.58, issue.14, pp.2853-2859, 2002.
DOI : 10.1016/S0040-4020(02)00158-8

T. K. Chakraborty, P. Srinivasu, E. Bikshapathy, R. Nagaraj, M. Vairamani et al., Cyclic Homooligomers of Furanoid Sugar Amino Acids, The Journal of Organic Chemistry, vol.68, issue.16, pp.6257-6263, 2003.
DOI : 10.1021/jo034586u

M. Menand, J. Blais, L. Hamon, J. Valéry, and J. Xie, Synthesis of Orthogonally Protected Cyclic Homooligomers from Sugar Amino Acids, The Journal of Organic Chemistry, vol.70, issue.11, pp.4423-4430, 2005.
DOI : 10.1021/jo0502899

URL : https://hal.archives-ouvertes.fr/hal-00017162

E. Locardi, M. Stockle, S. Gruner, and H. Kessler, Cyclic Homooligomers from Sugar Amino Acids:?? Synthesis, Conformational Analysis, and Significance, Journal of the American Chemical Society, vol.123, issue.34, pp.8189-8196, 2001.
DOI : 10.1021/ja010181k

J. A. Maddry, N. Bansal, L. E. Bermudez, R. N. Comber, and R. C. Raynolds, Homologated aza analogs of arabinose as antimycobacterial agents, Bioorganic & Medicinal Chemistry Letters, vol.8, issue.3, pp.237-252, 1998.
DOI : 10.1016/S0960-894X(98)00017-1

R. P. Tripathi, R. Tripathi, V. K. Tiwari, L. Bala, S. Sinha et al., Synthesis of glycosylated ??-amino acids as new class of antitubercular agents, European Journal of Medicinal Chemistry, vol.37, issue.9, pp.773-781, 2002.
DOI : 10.1016/S0223-5234(02)01398-3

D. Katiyar, R. C. Mishra, and R. P. Tripathi, Diastereoselective Synthesis of Galactopyranosyl Amino Esters and Their Transformation into C???Nucleosides, Journal of Carbohydrate Chemistry, vol.11, issue.1, pp.49-70, 2004.
DOI : 10.1016/S0008-6215(00)84534-6

A. S. Norgren and P. I. Arvidsson, -antigen, Org. Biomol. Chem., vol.13, issue.8, pp.1359-1361, 2005.
DOI : 10.1016/j.bmc.2004.09.009

A. S. Norgren, M. Geitmann, H. U. Danielson, and P. I. Arvidsson, Biomolecular recognition of glycosylated ??3-peptides by GalNAc specific lectins, Journal of Molecular Recognition, vol.562, issue.2, pp.132-138, 2007.
DOI : 10.1615/CritRevOncog.v6.i1.50

T. A. Martinek and F. Fulop, Side-chain control of beta-peptide secondary structures. Design principles, European Journal of Biochemistry, vol.81, issue.18, pp.3657-3659, 2003.
DOI : 10.1021/ja026114n

G. F. Springer, T and Tn, general carcinoma autoantigens, Science, vol.224, issue.4654, pp.1198-1203, 1984.
DOI : 10.1126/science.6729450

R. P. Cheng, S. H. Gellman, and W. F. Degrado, ??-Peptides:?? From Structure to Function, Chemical Reviews, vol.101, issue.10, pp.3219-3278, 2001.
DOI : 10.1021/cr000045i

G. V. Sharma, P. Nagendar, P. Jayaprakash, P. R. Krishna, K. V. Ramakrishna et al., 9/11 Mixed Helices in ??/?? Peptides Derived from C-Linked Carbo-??-Amino Acid andL-Ala Repeats, Angewandte Chemie International Edition, vol.13, issue.36, pp.5878-5882, 2005.
DOI : 10.1002/anie.200501247

G. V. Sharma, K. R. Reddy, P. R. Krishna, A. R. Sankar, P. Jayaprakash et al., Left-Handed Helical Twists in???Mixed??-Peptides??? Derived From Alternating C-Linked Carbo-??3-Amino Acids and??-hGly Units, Angewandte Chemie International Edition, vol.43, issue.30, pp.3961-3965, 2004.
DOI : 10.1002/anie.200353467

G. V. Sharma, V. B. Jadhav, K. V. Ramakrishna, P. Jayaprakash, K. Narsimulu et al., -Amino Acids, Journal of the American Chemical Society, vol.128, issue.45, pp.14657-14668, 2006.
DOI : 10.1021/ja064875a

R. C. Mishra, R. Tripathi, D. Katiyar, N. Tewari, D. Singh et al., Synthesis of glycosylated ??-Amino hydroxamates as new class of antimalarials, Bioorganic & Medicinal Chemistry, vol.11, issue.24, pp.5363-5374, 2003.
DOI : 10.1016/j.bmc.2003.09.038

G. V. Sharma, V. G. Reddy, A. S. Chander, and K. R. Reddy, Tetra-n-butylammonium fluoride: an efficient base for aza-Michael addition???synthesis of glycosyl ??-amino acid esters, Tetrahedron: Asymmetry, vol.13, issue.1, pp.21-24, 2002.
DOI : 10.1016/S0957-4166(02)00047-2

M. D. Disney, D. F. Hook, K. Namoto, and P. H. Seeberger, N-Linked Glycosylated??-Peptides Are Resistant to Degradation by Glycoamidase A, Chemistry & Biodiversity, vol.10, issue.12, pp.1624-1634, 2005.
DOI : 10.1002/cbdv.200590132

C. Bottcher and K. Burger, New types of glycoconjugates: O-glycosylated, N-glycosylated and O-,N-diglycosylated isoserine derivatives, Tetrahedron Letters, vol.44, issue.22, pp.4223-4226, 2003.
DOI : 10.1016/S0040-4039(03)00896-7

X. Zhu and R. R. Schmidt, Synthesis of ??-S-linked glycopeptides in water containing solution, Tetrahedron Letters, vol.44, issue.32, pp.6063-6067, 2003.
DOI : 10.1016/S0040-4039(03)01465-5

R. Falconer, A. Jablonkai, I. Toth, and I. , Efficient synthesis of thioglycosides via a Mitsunobu condensation, Tetrahedron Letters, vol.40, issue.49, pp.8663-8666, 1999.
DOI : 10.1016/S0040-4039(99)01834-1

C. Schips and T. Ziegler, ???Glycosyl Amino Acid Building Blocks for Combinatorial Neoglycopeptide Synthesis, Journal of Carbohydrate Chemistry, vol.42, issue.8-9, pp.773-788, 2005.
DOI : 10.1016/S0040-4039(00)80478-5

A. Dondoni, A. Massi, S. Sabbatini, and V. Bertolasi, Synthesis of C-glycosyl ??-amino acids by asymmetric Mannich-type three-component reactions, Tetrahedron Letters, vol.45, issue.11, pp.2381-2384, 2004.
DOI : 10.1016/j.tetlet.2004.01.070

T. P. Loh and S. L. Chen, -Catalyzed Three-Component Asymmetric Mannich-Type Reaction in Methanol, Organic Letters, vol.4, issue.21, pp.3647-3650, 2002.
DOI : 10.1021/ol0265968

J. C. Adrian and M. L. Snapper, Multiple Component Reactions:?? An Efficient Nickel-Catalyzed Reformatsky-Type Reaction and Its Application in the Parallel Synthesis of ??-Amino Carbonyl Libraries, The Journal of Organic Chemistry, vol.68, issue.6, pp.2143-2150, 2003.
DOI : 10.1021/jo026847q

C. 106-palomo, M. Oiarbide, A. Landa, M. C. Gonzalez-rego, J. M. Garcia et al., -Linked Glyco ??-Amino Acids through a Stereoselective ???Acetate??? Mannich Reaction as the Key Strategic Element, Journal of the American Chemical Society, vol.124, issue.29, pp.8637-8643, 2002.
DOI : 10.1021/ja026250s

Y. 108-inaba, S. Yano, and Y. Mikata, Facile synthesis of 2-(??-C-glucopyranosyl)-??-amino acid: a new class of glycopeptide building block, Tetrahedron Letters, vol.48, issue.6, pp.993-997, 2007.
DOI : 10.1016/j.tetlet.2006.12.006

C. 109-taillefumier, Y. Lakhrissi, M. Lakhrissi, and Y. Chapleur, Facile synthesis of fused furanosyl ??-amino acids from protected sugar lactones: incorporation into a peptide chain, Tetrahedron: Asymmetry, vol.13, issue.16, pp.1707-1711, 2002.
DOI : 10.1016/S0957-4166(02)00473-1

T. W. Brandstetter, C. De-la-fuente, Y. Kim, L. N. Johnson, S. Crook et al., Glucofuranose analogues of hydantocidin, Tetrahedron, vol.52, issue.32, pp.10721-10736, 1996.
DOI : 10.1016/0040-4020(96)00595-9

J. C. Estevez, M. D. Smith, A. L. Lane, C. Sarah, D. J. Watkin et al., Mimics of l-rhamnose: Anomeric spirohydantoins and diketopiperazines-approaches to novel N-linked glycopeptides of rhamnofuranose, Tetrahedron: Asymmetry, vol.7, issue.2, pp.387-390, 1996.
DOI : 10.1016/0957-4166(96)00013-4

J. C. Estevez, M. D. Smith, M. R. Wormald, G. S. Besra, P. J. Brennan et al., Mimics of l-rhamnose: Analogues of rhamnopyranose containing a constituent ??-amino acid at the anomeric position. A rhamnopyranose analogue of hydantocidin, Tetrahedron: Asymmetry, vol.7, issue.2, pp.391-394, 1996.
DOI : 10.1016/0957-4166(96)00014-6

J. C. Estevez, J. W. Burton, R. J. Estevez, M. R. Wormald, R. A. Dwek et al., Spirodiketopiperazines of mannofuranose: carbopeptoid ??-amino acid esters at the anomeric position of mannofuranose, Tetrahedron: Asymmetry, vol.9, issue.12, pp.2137-2154, 1998.
DOI : 10.1016/S0957-4166(98)00206-7

T. W. Brandstetter, Y. Kim, J. C. Son, H. M. Taylor, Q. De et al., Spirohydantoins of glucofuranose: Analogues of hydantocidin, Tetrahedron Letters, vol.36, issue.12, pp.2149-2152, 1995.
DOI : 10.1016/0040-4039(95)00198-L

T. W. Brandstetter, C. De-la-fuente, Y. Kim, R. I. Cooper, D. J. Watkin et al., ??-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptides, Tetrahedron, vol.52, issue.32, pp.10711-10720, 1996.
DOI : 10.1016/0040-4020(96)00594-7

T. W. Brandstetter, M. R. Wormald, R. A. Dwek, T. D. Butters, F. M. Platz et al., A galactopyranose analogue of hydantocidin, Tetrahedron: Asymmetry, vol.7, issue.1, pp.157-170, 1996.
DOI : 10.1016/0957-4166(95)00432-7

Y. Blériot, M. I. Simone, M. R. Wormald, R. A. Dwek, D. J. Watkin et al., Sugar amino acids at the anomeric position of carbohydrates: synthesis of spirocyclic amino acids of 6-deoxy-l-lyxofuranose, Tetrahedron: Asymmetry, vol.17, issue.15, pp.2276-2286, 2006.
DOI : 10.1016/j.tetasy.2006.07.027

A. Dondoni, M. Scherrmann, A. Marra, and J. Delepine, A General Synthetic Route to Anomeric .alpha.-Azido and .alpha.-Amino Acids and Formal Synthesis of (+)-Hidantocidin, The Journal of Organic Chemistry, vol.59, issue.24, pp.7517-7520, 1994.
DOI : 10.1021/jo00103a057

A. Dondoni and A. Marra, Methods for Anomeric Carbon-Linked and Fused Sugar Amino Acid Synthesis:?? The Gateway to Artificial Glycopeptides, Chemical Reviews, vol.100, issue.12, pp.4395-4421, 2000.
DOI : 10.1021/cr9903003

M. Lakhrissi and Y. Chapleur, A short route to ??-chloro- and ??-azido-ulosonic esters, Tetrahedron Letters, vol.39, issue.26, pp.4659-4662, 1998.
DOI : 10.1016/S0040-4039(98)00872-7

M. Lakhrissi and Y. Chapleur, Wittig Olefination of Lactones, Angewandte Chemie International Edition in English, vol.35, issue.7, pp.750-752, 1996.
DOI : 10.1002/anie.199607501

C. 125-taillefumier, S. Thielges, and Y. Chapleur, Anomeric spiroannelated 1,4-diazepine 2,5-diones from furano exo-glycals: towards a new class of spironucleosides, Tetrahedron, vol.60, issue.10, pp.2213-2224, 2004.
DOI : 10.1016/j.tet.2004.01.030

J. Coste, D. Le-nguyen, and B. Castro, PyBOP??: A new peptide coupling reagent devoid of toxic by-product, Tetrahedron Letters, vol.31, issue.2, pp.205-208, 1990.
DOI : 10.1016/S0040-4039(00)94371-5

L. A. 128-carpino, 1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive, Journal of the American Chemical Society, vol.115, issue.10, pp.4397-4398, 1993.
DOI : 10.1021/ja00063a082

D. T. Bong, T. D. Clark, J. R. Granja, and M. R. Ghadiri, Self-Assembling Organic Nanotubes, Angewandte Chemie International Edition, vol.10, issue.6, pp.988-1011, 2001.
DOI : 10.1007/978-94-011-3050-9_1

D. Seebach, J. Matthews, A. Meden, T. Wessels, C. Baerlocher et al., Cyclo-?-peptides: Structure and tubular stacking of cyclic tetramers of 3-aminobutanoic acid as determined from powder diffraction data, Helvetica Chimica Acta, vol.31, issue.1, pp.173-180, 1997.
DOI : 10.1002/nadc.19890371006

T. D. Clark, L. K. Buehler, and M. R. Ghadiri, -Peptide Nanotubes as Artificial Transmembrane Ion Channels, Journal of the American Chemical Society, vol.120, issue.4, pp.651-656, 1998.
DOI : 10.1021/ja972786f

J. R. 132-granja and M. R. Ghadiri, Channel-Mediated Transport of Glucose across Lipid Bilayers, Journal of the American Chemical Society, vol.116, issue.23, pp.10785-10786, 1994.
DOI : 10.1021/ja00102a054

S. Abele, P. Seiler, and D. Seebach, Synthesis, Crystal Structures, and Modelling of??-Oligopeptides Consisting of 1-(Aminomethyl)cyclopropanecarboxylic Acid: Ribbon-Type Arrangement of Eight-Membered H-Bonded Rings, Helvetica Chimica Acta, vol.82, issue.10, pp.1559-1571, 1999.
DOI : 10.1002/(SICI)1522-2675(19991006)82:10<1559::AID-HLCA1559>3.0.CO;2-A

C. 134-palomo, M. Oiarbide, and S. Bindi, A Concise ??-Lactam Route to Short Peptide Segments Containing ??,??-Disubstituted ??-Amino Acids, The Journal of Organic Chemistry, vol.63, issue.8, pp.2469-2474, 1998.
DOI : 10.1021/jo9712862

A. Mollica, M. Paradisi, D. Torino, S. Spisani, and G. Lucente, Hybrid ??/??-peptides: For-Met-Leu-Phe-OMe analogues containing geminally disubstituted ??2,2- and ??3,3-amino acids at the central position, Amino Acids, vol.137, issue.4, pp.453-459, 2006.
DOI : 10.1039/a704933a

L. 136-dheilly, C. Frechou, D. Beaupere, R. Uzan, and G. Demailly, A new route to C-glycosyl compounds. Wittig-type reaction promoted by zinc, Carbohydrate Research, vol.224, pp.301-306, 2002.
DOI : 10.1016/0008-6215(92)84116-A

L. 137-dheilly, C. Lievre, C. Frechou, and G. Demailly, Synth??ses de C-glycosides : Utilisations d'un d??riv?? de l'arsenic, Tetrahedron Letters, vol.34, issue.37, pp.5895-5898, 1993.
DOI : 10.1016/S0040-4039(00)73808-1

R. D. Dawe and B. Fraser-reid, Stereocontrolled routes to functionalized C-glycopyranosides, The Journal of Organic Chemistry, vol.49, issue.3, pp.522-528, 1984.
DOI : 10.1021/jo00177a027

F. Jacques, H. Dupeyroux, J. Joly, and Y. Chapleur, Towards glycosyl inositol mimics: Stereoselective synthesis of C-??-glucosyl-inositol derivatives via Diels-Alder reactions, Tetrahedron Letters, vol.38, issue.1, pp.73-76, 1997.
DOI : 10.1016/S0040-4039(96)02218-6

J. Angelo and J. Maddaluno, Enantioselective synthesis of .beta.-amino esters through high pressure-induced addition of amines to .alpha.,.beta.-ethylenic esters, Journal of the American Chemical Society, vol.108, issue.25, pp.8112-8114, 1986.
DOI : 10.1021/ja00285a051

S. G. Davies and O. Ichihara, Asymmetric synthesis of R-??-amino butanoic acid and S-??-tyrosine: Homochiral lithium amide equivalents for Michael additions to ??,??-unsaturated esters., Tetrahedron: Asymmetry, vol.2, issue.3, pp.183-186, 1991.
DOI : 10.1016/S0957-4166(00)82354-X

D. Cabaret and M. Wakselman, Synthesis of a Lipodisaccharidic Reagent for the Chemical Modification of Enzymes, Journal of Carbohydrate Chemistry, vol.75, issue.1, pp.55-63, 1990.
DOI : 10.1016/S0008-6215(00)90068-5

A. Giannis and K. Sandhoff, Stereoselective synthesis of ??- C-allyl-glycopyranosides, Tetrahedron Letters, vol.26, issue.12, pp.1479-1482, 1985.
DOI : 10.1016/S0040-4039(00)98529-0

H. 148-herzner, J. Eberling, M. Schultz, J. Zimmer, and H. Kunz, Oligosaccharide Synthesis via Electrophile-Induced Activation of Glycosyl-N-Allylcarbamates, Journal of Carbohydrate Chemistry, vol.17, issue.4, pp.759-776, 1998.
DOI : 10.1080/07328309808002350

M. M. Sim, H. Kondo, and C. Wong, Synthesis of dibenzyl glycosyl phosphites using dibenzyl N,N-diethylphosphoramidite as phosphitylating reagent: an effective route to glycosyl phosphates, nucleotides, and glycosides, Journal of the American Chemical Society, vol.115, issue.6, pp.2260-2267, 1993.
DOI : 10.1021/ja00059a023

Y. Lakhrissi, C. Taillefumier, M. Lakhrissi, and Y. Chapleur, Efficient conditions for the synthesis of C-glycosylidene derivatives: a direct and stereoselective route to C-glycosyl compounds, Tetrahedron: Asymmetry, vol.11, issue.2, pp.417-421, 2000.
DOI : 10.1016/S0957-4166(99)00586-8

J. Xie, A. Molina, and S. Czernecki, -Glycosides, Journal of Carbohydrate Chemistry, vol.50, issue.5, pp.481-498, 1999.
DOI : 10.1016/S0040-4020(01)86715-6

J. Elaridi, A. Thaqi, A. Prosser, W. R. Jackson, and A. J. Robinson, An enantioselective synthesis of ??2-amino acid derivatives, Tetrahedron: Asymmetry, vol.16, issue.7, pp.1309-1319, 2005.
DOI : 10.1016/j.tetasy.2005.01.048

H. Huang, Z. Zheng, H. Luo, C. Bai, X. Hu et al., -Mannitol:?? Broad Applications in Highly Enantioselective Rh-Catalyzed Hydrogenations, The Journal of Organic Chemistry, vol.69, issue.7, pp.2355-2361, 2004.
DOI : 10.1021/jo035627p

X. Hu and Z. Zheng, Practical Rh(I)-Catalyzed Asymmetric Hydrogenation of ??-(Acylamino)acrylates Using a New Unsymmetrical Hybrid Ferrocenylphosphine???Phosphoramidite Ligand:??? Crucial Influence of an N???H Proton in the Ligand, Organic Letters, vol.7, issue.3, pp.419-422, 2005.
DOI : 10.1021/ol047748x

C. Cimarelli, G. Palmieri, and E. Volpini, AN IMPROVED SYNTHESIS OF ENANTIOPURE ??-AMINO ACIDS, Synthetic Communications, vol.25, issue.19, pp.2943-2953, 2001.
DOI : 10.1039/c39930001153

C. Cimarelli, G. Palmieri, and G. Bartoli, Diastereo and enantioselective entry to ??-amino esters by hydride reduction of homochiral ??-enamino esters., Tetrahedron: Asymmetry, vol.5, issue.8, pp.1455-1458, 1994.
DOI : 10.1016/0957-4166(94)80111-8

G. Bartoli, C. Cimarelli, R. Dalpozzo, and G. Palmieri, A versatile route to ??-enamino esters by acylation of lithium enamines with diethyl carbonate or benzyl chloroformate, Tetrahedron, vol.51, issue.31, pp.8613-8622, 1995.
DOI : 10.1016/0040-4020(95)00476-O

K. M. 159-sun, R. D. Dawe, and B. Fraser-reid, Synthesis and ???anomerization??? of C-glycosyl compounds related to some heterocyclic natural products, Carbohydrate Research, vol.171, issue.1, pp.35-47, 1987.
DOI : 10.1016/S0008-6215(00)90877-2

M. Nour, K. Tan, R. Jankowski, and C. Cave, Easy access to optically active Hagemann's esters, Tetrahedron: Asymmetry, vol.12, issue.5, pp.765-769, 2001.
DOI : 10.1016/S0957-4166(01)00105-7

A. K. Awasthi, M. L. Boys, K. J. Cain-janicki, P. J. Colson, W. W. Doubleday et al., Practical Enantioselective Synthesis of ??-Substituted-??-amino Esters, The Journal of Organic Chemistry, vol.70, issue.14, pp.5387-5397, 2005.
DOI : 10.1021/jo050177h

L. E. 162-overman, Thermal and mercuric ion catalyzed [3,3]-sigmatropic rearrangement of allylic trichloroacetimidates. 1,3 Transposition of alcohol and amine functions, Journal of the American Chemical Society, vol.96, issue.2, pp.597-599, 1974.
DOI : 10.1021/ja00809a054

L. E. 163-overman, A general method for the synthesis of amines by the rearrangement of allylic trichloroacetimidates. 1,3 Transposition of alcohol and amine functions, Journal of the American Chemical Society, vol.98, issue.10, pp.2901-2910, 1976.
DOI : 10.1021/ja00426a038

I. Jaunzeme, A. Jirgensons, V. Kauss, and E. Liepins, Diastereoselectivity in the Overman rearrangement of O-cyclohexylideneethylimidates, Tetrahedron Letters, vol.47, issue.23, pp.3885-3887, 2006.
DOI : 10.1016/j.tetlet.2006.03.174

A. Montero, E. Mann, and B. Herradon, The Overman rearrangement in carbohydrate chemistry: stereoselective synthesis of functionalized 3-amino-3,6-dihydro-2H-pyrans and incorporation in peptide derivatives, Tetrahedron Letters, vol.46, issue.3, pp.401-405, 2005.
DOI : 10.1016/j.tetlet.2004.11.109

C. E. Anderson and L. E. Overman, Catalytic Asymmetric Rearrangement of Allylic Trichloroacetimidates. A Practical Method for Preparing Allylic Amines and Congeners of High Enantiomeric Purity, Journal of the American Chemical Society, vol.125, issue.41, pp.12412-12413, 2003.
DOI : 10.1021/ja037086r

S. F. 167-kirsch, L. E. Overman, and M. P. Watson, Monomeric Cobalt Oxazoline Palladacycles (COP). Useful Catalysts for Catalytic Asymmetric Rearrangement of Allylic Trichloroacetimidates, The Journal of Organic Chemistry, vol.69, issue.23, pp.8101-8104, 2004.
DOI : 10.1021/jo0487092

L. E. 168-overman, Mercury(II)- and Palladium(II)-Catalyzed [3,3]-Sigmatropic Rearrangements [New Synthetic Methods (46)], Angewandte Chemie International Edition in English, vol.24, issue.8, pp.579-586, 1984.
DOI : 10.1016/S0040-4039(01)99812-0

A. Chen, I. Savage, E. J. Thomas, and P. D. Wilson, Asymmetric ??-aminoacid synthesis using [3.3] rearrangement of allylic trifluoroacetimidates: Synthesis of thymine polyoxin C, Tetrahedron Letters, vol.34, issue.42, pp.6769-6772, 1993.
DOI : 10.1016/S0040-4039(00)61697-0

D. M. Vyas, Y. Chiang, and T. W. Doyle, A practical synthesis of racemic vinylglycine from (z)-2-butene-1,4-diol, The Journal of Organic Chemistry, vol.49, issue.11, pp.2037-2039, 1984.
DOI : 10.1021/jo00185a049

W. R. 172-roush, J. A. Straub, and R. J. Brown, Total synthesis of carbohydrates. 5. Stereochemistry of the epoxidations of acyclic allylic amides. Applications towards the synthesis of 2,3,6-trideoxy-3-aminohexoses, The Journal of Organic Chemistry, vol.52, issue.23, pp.5127-5136, 1987.
DOI : 10.1021/jo00232a014

D. Urabe, K. Sugino, T. Nishikawa, and M. Isobe, A novel deprotection of trichloroacetamide, Tetrahedron Letters, vol.45, issue.51, pp.9405-9407, 2004.
DOI : 10.1016/j.tetlet.2004.10.099

J. M. Janey, Y. Hsiao, and J. D. Armstrong, Proline-Catalyzed, Asymmetric Mannich Reactions in the Synthesis of a DPP-IV Inhibitor, The Journal of Organic Chemistry, vol.71, issue.1, pp.390-392, 2006.
DOI : 10.1021/jo0519458

C. S. Dexter, R. F. Jackson, J. B. Elliott, S. A. Kolodziej, A. M. Scates et al., Synthesis of Enantiomerically Pure ??- and ??-Amino Acid Derivatives Using Functionalized Organozinc Reagents, The Journal of Organic Chemistry, vol.64, issue.20, pp.7579-7585, 1998.
DOI : 10.1021/jo990941y

A. Cheguillaume, F. Lehardy, K. Bouget, M. Baudy-floc-'h, and P. Le-grel, Submonomer Solution Synthesis of Hydrazinoazapeptoids, a New Class of Pseudopeptides, The Journal of Organic Chemistry, vol.64, issue.8, pp.2924-2927, 1999.
DOI : 10.1021/jo981487l

G. 184-lelais, D. L. Seebach, J. Vidal, A. Collet, and A. Amour, Synthesis, CD Spectra, and Enzymatic Stability of??2-Oligoazapeptides Prepared from (S)-2-Hydrazino Carboxylic Acids Carrying the Side Chains of Val, Ala, and Leu, Helvetica Chimica Acta, vol.86, issue.12, pp.4152-4258, 1998.
DOI : 10.1002/hlca.200390342

R. Gunther and H. Hofmann, Hydrazino Peptides as Foldamers:?? An Extension of the ??-Peptide Concept, Journal of the American Chemical Society, vol.123, issue.2, pp.247-255, 2001.
DOI : 10.1021/ja001066x

A. 188-salaun, A. Favre, B. Le-grel, M. Potel, and P. Le-grel, -peptides, The Journal of Organic Chemistry, vol.71, issue.1, pp.150-157, 2006.
DOI : 10.1021/jo051887q

L. Grel, P. Salaun, A. Potel, M. Le-grel, B. Lassagne et al., -Cyclohexapeptides:?? Pseudopeptidic Macrocycles with Interesting Conformational and Configurational Properties Slow Pyramidal Nitrogen Inversion in 24-Membered Rings!, The Journal of Organic Chemistry, vol.71, issue.15, pp.5638-5645, 2006.
DOI : 10.1021/jo0608467

J. Vidal, L. Guy, S. Sterin, and A. Collet, Electrophilic amination: preparation and use of N-Boc-3-(4-cyanophenyl)oxaziridine, a new reagent that transfers a N-Boc group to N- and C-nucleophiles, The Journal of Organic Chemistry, vol.58, issue.18, pp.4791-4793, 1993.
DOI : 10.1021/jo00070a007

J. Vidal, J. Hannachi, G. N. Hourdin, J. Mulatier, and A. Collet, N-Boc-3-trichloromethyloxaziridine: a new, powerful reagent for electrophilic amination, Tetrahedron Letters, vol.39, issue.48, pp.8845-8848, 1998.
DOI : 10.1016/S0040-4039(98)01983-2

D. Luca, L. Falorni, M. Giacomelli, G. Porcheddu, and A. , New pyrazole containing bicarboxylic ??-amino acids: mimics of the cis amide bond, Tetrahedron Letters, vol.40, issue.49, pp.8701-8704, 1999.
DOI : 10.1016/S0040-4039(99)01847-X

J. Viret, J. Gabard, and A. Collet, Practical synthesis of optically active ??-hydrazino acids from ??-amino acids, Tetrahedron, vol.43, issue.5, pp.891-894, 1987.
DOI : 10.1016/S0040-4020(01)90026-2

K. Achiwa and S. I. Yamada, Hydrazino acids and peptides. A new general synthesis of L-??-hydrazino acids from L-??-amino acids, Tetrahedron Letters, vol.16, issue.31, pp.2701-2704, 1975.
DOI : 10.1016/S0040-4039(00)75218-X

C. Gennari, L. Colombo, and G. Bertolini, Asymmetric electrophilic amination: synthesis of .alpha.-amino and .alpha.-hydrazino acids with high optical purity, Journal of the American Chemical Society, vol.108, issue.20, pp.6394-6395, 1986.
DOI : 10.1021/ja00280a049

D. A. Evans, T. C. Britton, R. L. Dorow, and J. F. Dellaria, Stereoselective amination of chiral enolates. A new approach to the asymmetric synthesis of .alpha.-hydrazino and .alpha.-amino acid derivatives, Journal of the American Chemical Society, vol.108, issue.20, pp.6395-6397, 1986.
DOI : 10.1021/ja00280a050

N. Brosse, M. F. Pinto, J. Bodiguel, and B. Jamart-gregoire, A New Synthetic Route to Protected ??-Hydrazinoesters in High Optical Purity Using the Mitsunobu Protocol, The Journal of Organic Chemistry, vol.66, issue.8, pp.2869-2873, 2001.
DOI : 10.1021/jo005696t

I. 200-bouillon, N. Brosse, R. Vanderesse, and B. Jamart-gregoire, Synthesis of N??-Z, N??-Fmoc or Boc protected ??-hydrazinoacids and study of the coupling reaction in solution of N??-Z-??-hydrazinoesters, Tetrahedron, vol.63, issue.10, pp.2223-2234, 2007.
DOI : 10.1016/j.tet.2006.12.085

I. 201-bouillon, N. Brosse, R. Vanderesse, and B. Jamart-gregoire, Liquid and solid phase syntheses of orthogonally protected ??-hydrazinoacid derivatives, Tetrahedron Letters, vol.45, issue.18, pp.3569-3572, 2004.
DOI : 10.1016/j.tetlet.2004.03.063

A. Carmi, G. Pollak, and H. Yellin, ??-Hydrazino- Acids. I. ??-Hydrazinoaliphatic Acids and ??-(1-Methylhydrazino)aliphatic Acids, The Journal of Organic Chemistry, vol.25, issue.1, pp.44-46, 1959.
DOI : 10.1021/jo01071a013

O. Busnel, L. Bi, H. Dali, A. Cheguillaume, S. Chevance et al., -amino Acids and ??-Amino Acids, The Journal of Organic Chemistry, vol.70, issue.26, pp.10701-10708, 2005.
DOI : 10.1021/jo051585o

J. C. 205-danilewicz, S. M. Abel, A. D. Brown, P. V. Fish, E. Hawkeswood et al., Design of Selective Thrombin Inhibitors Based on the (R)-Phe-Pro-Arg Sequence, Journal of Medicinal Chemistry, vol.45, issue.12, pp.2432-2453, 2002.
DOI : 10.1021/jm011133d

L. A. 207-carpino, R. E. Padykula, D. E. Barr, F. H. Hall, J. G. Krause et al., Synthesis, characterization, and thermolysis of 7-amino-7-azabenzonorbornadienes, The Journal of Organic Chemistry, vol.53, issue.11, pp.2565-2572, 1988.
DOI : 10.1021/jo00246a031

M. Surfraz, R. King, S. Mather, S. Biagini, and P. Blower, Tc Radiolabeling, Journal of Medicinal Chemistry, vol.50, issue.6, pp.1418-1422, 2007.
DOI : 10.1021/jm061274l

E. Kazzouli, S. Koubachi, J. Berteina-raboin, S. Mouaddib, A. Guillaumet et al., A mild and selective method for the N-Boc deprotection by sodium carbonate, Tetrahedron Letters, vol.47, issue.48, pp.8575-8577, 2006.
DOI : 10.1016/j.tetlet.2006.09.129

G. 211-cignarella and P. Sanna, Diuretic agents related to indapamide. 1. Synthesis and activity of 1-substituted 2-(4-chloro-3-sulfamoylbenzamido)isoindolines, Journal of Medicinal Chemistry, vol.24, issue.8, pp.1003-1006, 1981.
DOI : 10.1021/jm00140a018

R. H. Sifferd and V. Vigneaud, The journal of biological chemistry, pp.753-761, 1934.

G. J. 215-chittenden, A simplified synthesis of ??-d-galactopyranose 1,3,4,6-tetraacetate, Carbohydrate Research, vol.183, issue.1, pp.140-143, 1988.
DOI : 10.1016/0008-6215(88)80055-7

P. Asakura, Clay Catalyzed Acetonation: A Simple Method for the Preparation of Isopropylidene Carbohydrates, Journal of Carbohydrate Chemistry, vol.92, issue.2, pp.231-240, 1996.
DOI : 10.1016/S0008-6215(00)81433-0

E. Brenna, C. Fuganti, P. Grasselli, S. Serra, and S. Zambotti, A Novel General Route for the Synthesis of C-Glycosyl Tyrosine Analogues, Chemistry - A European Journal, vol.8, issue.8, pp.1872-1876, 2002.
DOI : 10.1002/1521-3765(20020415)8:8<1872::AID-CHEM1872>3.0.CO;2-A

G. Schmidt, M. R. Richards, C. J. Stewart, and V. H. Cheldelin, Einfache Synthese von ??-und ??-O-Glykosylimidaten; Herstellung von Glykosiden und Disacchariden, Angewandte Chemie, vol.99, issue.9, pp.763-764, 1952.
DOI : 10.1002/9780470771495.ch9

I. R. , 1. , 1. , and 2. Ar, C=O) 3444 (=CH) RMN 1 H (CDCl 3 , 400 MHz) : ? (ppm) : 1,41 (s, 3H, pp.1745507125-380

L. Sous-atmosphère-d-'argon and . Composé, 23 mmol) est dissout dans 5 mL de tétrahydrofurane. La solution est portée à 0°C puis 4 éq mL, 0,92 mmol) sont additionnés. Le mélange est agité pendant 4 heures à température ambiante. Le mélange est ensuite refroidi à 0°C et 14 mL de soude (2M) sont additionnées suivi de 9,5 mL de peroxyde d'hydrogène. L'agitation est maintenue une heure, le mélange réactionnel est ensuite lavé par 20 mL d'eau, la phase organique est séchée sur MgSO 4 , concentrée sous pression réduite. Le résidu est purifié par chromatographie sur gel de silice avec le mélange éluant H, mmol) est obtenu avec un rendement de 61 %, sous la forme d'un mélange de diastéréoisomères inséparables, p.2109514

. Ph, 98 (m, 4H, 4x-OCH 2 Ph, pp.80-416

2. Ar, 40 (dd, 1H, J gem = 16,1 Hz, J 2'a-3' = 8,3 Hz (dd, 1H, J 2'b-3' = 4,3 Hz, RMN 1 H (CDCl 3 , 250 MHz) : ? (ppm) : 2, pp.5643-3699341

. Le-couplage-s-'effectue-suivant-la-procédure-générale-de-couplage-au-py, BOP 2 avec 350 mg d'amine 222 (0,5 mmol), 129 mg d'acide aminé 217 (0,625 mmol), 357 mg de Py-BOP (0,625 mmol) et 96 µL de triéthylamine (0,625 mmol) Le brut est purifié sur colonne chromatographique avec le mélange éluant H, p.75

I. R. , 2. Nhcm, and 2. Ar, 400 MHz) : ? (ppm) : 1,47 (s, 9H, Hz, J 2'a-3' = 2,8 Hz, J 2'b-3' = 2,4 Hz 2 PhNH (amide) ), pp.1739-1745

I. R. , 1. , and 2. Ar, Analyse : Calculée : C : 72,12 H : 7,38 N : 4,10, Trouvée : C : 71,92 H : 7,19 N : 4,10. RMN 1 H (CDCl 3 , 400 MHz) : ? (ppm) : 1,43 (s, 9H, 2 Ph, pp.1700-1703

. Anhydro, ,8-tétra-O-benzyl-D-glycero-D-ido-octitol-1-yl]-2-[tert- butyloxyacetyl]-(tert-butoxycarbonyl) hydrazine 251, 2006.

. Anhydro, ,8-tétra-O-benzyl]-1-[(tert-butyloxyacetyl)amino]- 1, p.256, 2006.

A. 0°c and L. Composé, 19 mmol) est mis en solution dans 5 mL d'un mélange acétonitrile/diéthylamine (2/1 en volume) Au bout d'une heure d'agitation à température ambiante, le milieu réactionnel est concentré sous pression réduite. Le brut réactionnel est purifié par chromatographie sur gel de silice avec un mélange éluant H/AE : 3/1, p.248

I. R. and 2. Ar, C=O) 3428 (NH) RMN 1 H (CDCl 3 , 250 MHz) : ? (ppm) : 1,43 (s, 9H, 3xCH 3(tBu) ), 1,50 (s, 3H, CH 3, 2 Ph), pp.172860-124, 1921.

. Le-composé-265, Ala-OtBu 264 (65 mg, 1,1 éq., 0,45 mmol) suivant la méthode générale de couplage 11 en utilisant 1,5 éq. de NMM (52 µL, 0,60 mmol) et 1,5 éq. d'ICF (90 µL, 0,60 mmol) Après une purification par chromatographie moyenne pression sur gel de silice avec le mélange éluant H/AE : 1/3, pp.25-265

5. Hz and H. Ar, (s, 1H, pp.411533-411540

1. Hz, (s, 2H, -OCH 2 Ph, pp.99-40705

. En-suivant-la-procédure-générale, 45 mmol) sont alkylés en présence de 1,3 éq. de bromoacétate de tert-butyle (0,1 mL, 0,58 mmol) et de 43 mg de K 2 CO 3 (1 éq., 0,45 mmol) Après une purification par chromatographie moyenne pression sur gel de silice avec le gradient d'éluant H/AE : 3/2 à AE pur, pp.270-272

. Le-composé-273, mmol) est mis en solution dans 10 mL d'un mélange acide trifluoroacétique-méthanol (1/1 en volume) Le milieu est maintenu sous agitation pendant 18 heures puis il est concentré sous pression réduite, Le brut réactionnel est utilisé sans autre purification, p.15