C. Sandiford, A. Tatham, R. Fido, J. Welch, M. Jones et al., Identification of the major water/salt insoluble wheat proteins involved in cereal hypersensitivity, Clinical & Experimental Allergy, vol.16, issue.10, pp.1120-1129, 1997.
DOI : 10.1016/S0031-9422(00)86672-8

P. Shewry and N. Halford, Cereal seed storage proteins: structures, properties and role in grain utilization, Journal of Experimental Botany, vol.53, issue.370
DOI : 10.1093/jxb/41.4.385

C. Nioi, R. Kapel, E. Rondags, and I. Marc, Selective extraction, structural characterisation and antifungal activity assessment of napins from an industrial rapeseed meal, Food Chemistry, vol.134, issue.4, pp.2149-2155, 2012.
DOI : 10.1016/j.foodchem.2012.04.017

URL : https://hal.archives-ouvertes.fr/hal-00777695

M. Duranti, Grain legume proteins and nutraceutical properties, Fitoterapia, vol.77, issue.2, pp.67-82, 2006.
DOI : 10.1016/j.fitote.2005.11.008

A. Moure, J. Sineiro, H. Dominguez, and J. Parajò, Functionality of oilseed protein products: A review, Food Research International, vol.39, issue.9, pp.945-963, 2006.
DOI : 10.1016/j.foodres.2006.07.002

B. Arifin, A. Bono, Y. Farm, A. Ling, and S. Fui, Protein Extraction from Palm Kernel Meal, J Appl Sci, vol.9, issue.17, pp.2996-3004, 2009.

P. Delgado-moreno and M. Mingorance, Design of experiments in environmental chemistry studies: Example of the extraction of triazines from soil after olive cake amendment, Journal of Hazardous Materials, vol.162, issue.2-3, pp.1121-1128, 2009.
DOI : 10.1016/j.jhazmat.2008.05.148

M. Aider and C. Barbana, Canola proteins: composition, extraction, functional properties, bioactivity, applications as a food ingredient and allergenicity ??? A practical and critical review, Trends in Food Science & Technology, vol.22, issue.1, pp.21-39, 2011.
DOI : 10.1016/j.tifs.2010.11.002

I. Rodrigues, J. Coelho, and M. Carvalho, Isolation and valorisation of vegetable proteins from oilseed plants: Methods, limitations and potential, Journal of Food Engineering, vol.109, issue.3, pp.337-346, 2011.
DOI : 10.1016/j.jfoodeng.2011.10.027

C. Pickardt, S. Neidhart, C. Griesbach, M. Dube, U. Knauf et al., Optimisation of mild-acidic protein extraction from defatted sunflower (Helianthus annuus L.) meal, Food Hydrocolloids, vol.23, issue.7, pp.1966-1973, 2009.
DOI : 10.1016/j.foodhyd.2009.02.001

E. Firatligil-durmus and O. Evranuz, Response surface methodology for protein extraction optimization of red pepper seed (Capsicum frutescens) Food Sci Technol, pp.226-231, 2010.

R. Viennet, C. Fonteix, and I. Marc, New multicriteria optimization method based on the use of a diploid genetic algorithm: Example of an industrial problem, Artif Evol, vol.1063, pp.120-127, 1996.
DOI : 10.1007/3-540-61108-8_34

A. Geoffrion, J. Dyer, and A. Feinberg, An Interactive Approach for Multi-Criterion Optimization, with an Application to the Operation of an Academic Department, Management Science, vol.19, issue.4-part-1, pp.357-368
DOI : 10.1287/mnsc.19.4.357

G. Chabanon, I. Chevalot, X. Framboisier, S. Chenu, and I. Marc, Hydrolysis of rapeseed protein isolates: Kinetics, characterization and functional properties of hydrolysates, Process Biochemistry, vol.42, issue.10, pp.1419-1428, 2007.
DOI : 10.1016/j.procbio.2007.07.009

URL : https://hal.archives-ouvertes.fr/hal-00277822

G. Neumann, R. Condron, I. Thomas, and G. Polya, Purification and sequencing of multiple forms of Brassica napus seed napin small chains that are calmodulin antagonists and substrates for plant calcium-dependent protein kinase, Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol.1295, issue.1, pp.23-33, 1996.
DOI : 10.1016/0167-4838(96)00006-4

R. Monsalve, M. Villalba, C. López-otín, and R. Rodríguez, Structural analysis of the small chain of the 2S albumin, napin nIII, from rapeseed. Chemical and spectroscopic evidence of an intramolecular bond formation, Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol.1078, issue.2, pp.265-272, 1991.
DOI : 10.1016/0167-4838(91)90568-K

L. Muniglia, N. Kiss, L. Fonteix, C. Marc, and I. , Multicriteria optimization of a single-cell oil production, European Journal of Operational Research, vol.153, issue.2
DOI : 10.1016/S0377-2217(03)00158-9

E. Perrin, A. Mandrille, M. Oumoun, C. Fonteix, and I. Marc, Optimisation globale par strat??gie d'??volution, RAIRO - Operations Research, vol.31, issue.2
DOI : 10.1051/ro/1997310201611

R. Carlson, Design of Experiments, Principles and Applications, J, vol.15, issue.5, pp.495-496, 2001.

Z. Pawlak, ROUGH SET THEORY AND ITS APPLICATIONS TO DATA ANALYSIS, Cybernetics and Systems, vol.29, issue.7, pp.661-688, 1998.
DOI : 10.1080/019697298125470

C. Huang, W. Liang, S. Lin, T. Tseng, and H. Chiang, A rough set based approach to patent development with the consideration of resource allocation, Expert Systems with Applications, vol.38, issue.3, pp.1980-1992, 2011.
DOI : 10.1016/j.eswa.2010.07.132

L. Shen, X. Wang, Z. Wang, Y. Wu, and J. Chen, Studies on tea protein extraction using alkaline and enzyme methods, Food Chemistry, vol.107, issue.2, pp.929-938, 2008.
DOI : 10.1016/j.foodchem.2007.08.047

T. Jyothi, S. Sinha, S. Singh, A. Surolia, A. Rao et al., Napin from Brassica juncea: Thermodynamic and structural analysis of stability, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol.1774, issue.7, pp.907-919, 2007.
DOI : 10.1016/j.bbapap.2007.04.008

E. Y. Adje, R. Balti, M. Kouach, P. Dhulster, D. Guillochon et al., Obtaining antimicrobial peptides by controlled peptic hydrolysis of bovine hemoglobin, International Journal of Biological Macromolecules, vol.49, issue.2, pp.143-153, 2011.
DOI : 10.1016/j.ijbiomac.2011.04.004

E. Y. Adje, R. Balti, M. Kouach, D. Guillochon, and N. Nedjar-arroume, ?? 67-106 of bovine hemoglobin: a new family of antimicrobial and angiotensin I-converting enzyme inhibitory peptides, European Food Research and Technology, vol.32, issue.4, 2011.
DOI : 10.1093/nar/gkh025

A. Aschi, N. Mbarek, M. Othman, and A. Gharbi, Study of thermally and chemically unfolded conformations of bovine serum albumin by means of dynamic light scattering, Materials Science and Engineering: C, vol.28, issue.5, pp.594-600, 2008.

G. Chabanon, L. Alves-da-costa, B. Farges, C. Harscoat, S. Chenu et al., Influence of the rapeseed protein hydrolysis process on CHO cell growth, Bioresource Technology, vol.99, issue.15, 2008.
DOI : 10.1016/j.biortech.2007.12.070

URL : https://hal.archives-ouvertes.fr/hal-00301343

C. Cui, X. Zhou, M. Zhao, and B. Yang, Effect of thermal treatment on the enzymatic hydrolysis of chicken proteins, Innovative Food Science & Emerging Technologies, vol.10, issue.1, pp.37-41, 2009.
DOI : 10.1016/j.ifset.2008.09.003

P. Dhulster, R. Kapel, R. Froidevaux, N. Nedjar-arroume, A. Fertin-bazus et al., Advancement in intermediate opioid peptide production in an enzymatic membrane reactor assisted by solvent extraction, Desalination, vol.148, issue.1-3, pp.221-226, 2002.
DOI : 10.1016/S0011-9164(02)00701-4

E. Dufour, G. Hervé, and T. Haertle, Hydrolysis of ??-lactoglobulin by thermolysin and pepsin under high hydrostatic pressure, Biopolymers, vol.8, issue.5, pp.475-483, 2004.
DOI : 10.1016/0003-2697(90)90453-G

M. R. Eftink and M. C. Shastry, [12] Fluorescence methods for studying kinetics of protein-folding reactions, Methods in enzymology, vol.278, pp.258-286, 1997.
DOI : 10.1016/S0076-6879(97)78014-5

R. Froidevaux, F. Krier, N. Nedjar-arroume, D. Vercaigne-marko, E. Kosciarz et al., Antibacterial activity of a pepsin-derived bovine hemoglobin fragment, FEBS Letters, vol.49, issue.1-2, pp.159-163, 2001.
DOI : 10.1146/annurev.mi.49.100195.001425

URL : https://hal.archives-ouvertes.fr/hal-00280593

V. Y. Grinberg, T. V. Burova, T. Haertlé, and V. B. Tolstoguzov, Interpretation of DSC data on protein denaturation complicated by kinetic and irreversible effects, Journal of Biotechnology, vol.79, issue.3, pp.79-269, 2000.
DOI : 10.1016/S0168-1656(00)00243-1

R. Kapel, E. Rahhou, D. Lecouturier, D. Guillochon, and P. Dhulster, Characterization of an antihypertensive peptide from an Alfalfa white protein hydrolysate produced by a continuous enzymatic membrane reactor, Process Biochemistry, vol.41, issue.9, pp.41-1961, 2006.
DOI : 10.1016/j.procbio.2006.04.019

H. Korhonen and A. Pihlanto, Bioactive peptides: Production and functionality, International Dairy Journal, vol.16, issue.9, pp.945-960, 2006.
DOI : 10.1016/j.idairyj.2005.10.012

C. Megías, J. Pedroche, M. M. Yust, M. Alaiz, J. Girón-calle et al., Purification of angiotensin converting enzyme inhibitory peptides from sunflower protein hydrolysates by reversephase chromatography following affinity purification, LWT-Food Science and Technology, vol.4, issue.1, pp.228-232, 2009.

R. I. Monsalve, M. Villalba, C. López-otín, and R. Rodríguez, Structural analysis of the small chain of the 2S albumin, napin nIII, from rapeseed. Chemical and spectroscopic evidence of an intramolecular bond formation, BBA) -Protein Structure and Molecular Enzymology, pp.1078-265, 1991.
DOI : 10.1016/0167-4838(91)90568-K

E. Murén, B. Ek, I. Björk, and L. Rask, Structural Comparison of the Precursor and the Mature Form of Napin, the 2S Storage Protein in Brassica napus, European Journal of Biochemistry, vol.43, issue.2, pp.214-219, 2004.
DOI : 10.1006/abio.1993.1079

N. Nedjar-arroume, V. Dubois-delval, E. Y. Adje, J. Traisnel, F. Krier et al., Bovine hemoglobin: An attractive source of antibacterial peptides, Peptides, vol.29, issue.6, pp.29-969, 2008.
DOI : 10.1016/j.peptides.2008.01.011

C. Nioi, R. Kapel, E. Rondags, and I. Marc, Selective extraction, structural characterisation and antifungal activity assessment of napins from an industrial rapeseed meal, Food Chemistry, vol.134, issue.4, pp.2149-2155, 2012.
DOI : 10.1016/j.foodchem.2012.04.017

URL : https://hal.archives-ouvertes.fr/hal-00777695

C. N. Pace, D. V. Laurents, and J. A. Thomson, pH dependence of the urea and guanidine hydrochloride denaturation of ribonuclease A and ribonuclease T1, Biochemistry, vol.29, issue.10, pp.29-2564, 1990.
DOI : 10.1021/bi00462a019

. Une-nouvelle-fois, les résultats montrent que la durée d'incubation du substrat influence la cinétique de protéolyse. 3.2. Effet de la durée d'incubation sur la qualité des mélanges obtenus

J. Banga, E. Balsa-canto, C. Moles, and A. Alonso, Improving food processing using modern optimization methods, Trends in Food Science & Technology, vol.14, issue.4, pp.131-144, 2003.
DOI : 10.1016/S0924-2244(03)00048-7

J. Barciszewski, S. Maciej, and . Haertlé, Minireview: Analysis of Rape Seed Napin Structure and Potential Roles of the Storage Protein, Journal of Protein Chemistry, vol.19, issue.4, pp.249-254, 2000.
DOI : 10.1023/A:1007085627485

C. Baszczynski and L. Fallis, Isolation and nucleotide sequence of a genomic clone encoding a new Brassica napus napin gene, Plant Molecular Biology, vol.74, issue.4, pp.633-635, 1990.
DOI : 10.1007/BF00027511

B. Baudet and J. Evrard, Tourteau à basse teneur en glucosinolates (BTG) Cahier technique colza, 1998.

J. Bautista, I. Hernandez-pinzon, M. Alaiz, and J. Parrado, Low Molecular Weight Sunflower Protein Hydrolysate with Low Concentration in Aromatic Amino Acids, Journal of Agricultural and Food Chemistry, vol.44, issue.4, pp.44-967, 1996.
DOI : 10.1021/jf940726c

D. Beasley, D. Bull, and R. Martin, A Sequential Niche Technique for Multimodal Function Optimization, Evolutionary Computation, vol.5, issue.3, pp.101-125, 1993.
DOI : 10.1162/evco.1993.1.1.25

J. Bell, Factors affecting the nutritional value of canola meal: A review, Canadian Journal of Animal Science, vol.11, issue.4, pp.689-697, 1993.
DOI : 10.4141/cjas93-075

S. Bérot, J. Compoint, C. Larré, C. Malabat, and J. Guéguen, Large scale purification of rapeseed proteins (Brassica napus L.), Journal of Chromatography B, vol.818, issue.1, pp.35-42, 2005.
DOI : 10.1016/j.jchromb.2004.08.001

S. Berot, Y. Popineau, J. Compoint, C. Blassel, and B. Chaufer, Ultrafiltration to fractionate wheat polypeptides, Journal of Chromatography B: Biomedical Sciences and Applications, vol.753, issue.1, pp.29-35, 2001.
DOI : 10.1016/S0378-4347(00)00418-7

G. Biziulevi?ius, O. Kislukhina, J. Kazlauskait?, and V. ?ukait?, Food-protein enzymatic hydrolysates possess both antimicrobial and immunostimulatory activities: a ??????cause and effect?????? theory of bifunctionality, FEMS Immunology & Medical Microbiology, vol.46, issue.1, pp.131-138, 2006.
DOI : 10.1007/978-3-0348-9225-4_22

M. Bjurlin, S. Bloomer, and C. Nelson, Characterization of proteolytic activity of proteases, Biotechnology, vol.24, issue.35, pp.191-195, 2002.

W. Blom, A. Kunst, M. Hakkaart, G. Luli, and B. Van-schie, Peptides for Tissue and Cell Culture Media, pp.96-26266, 1996.

C. Bos, G. Airinei, F. Mariotti, R. Benamouzig, S. Bérot et al., The Poor Digestibility of Rapeseed Protein Is Balanced by Its Very High Metabolic Utilization in Humans, The Journal of Nutrition, vol.42, issue.3, pp.594-600, 2007.
DOI : 10.1016/0377-8401(95)00920-5

URL : https://hal.archives-ouvertes.fr/hal-01173370

S. Bouhallab and G. Henry, Transmission of a hydrophobic peptide through an inorganic ultrafiltration membrane: effect of membrane support, Journal of Membrane Science, vol.104, issue.1-2, pp.73-79, 1995.
DOI : 10.1016/0376-7388(95)00013-3

S. Bouhallab and G. Henry, Enzymatic hydrolysis of sodium caseinate in a continuous ultrafiltration reactor using an inorganic membrane, Applied Microbiology and Biotechnology, vol.42, issue.5, pp.692-696, 1995.
DOI : 10.1007/BF00171946

G. Box and N. Draper, Empirical model-building and response surfaces, 1987.

M. Brune, L. Hallberg, and A. Skaanberg, Determination of Iron-Binding Phenolic Groups in Foods, Journal of Food Science, vol.16, issue.1, pp.128-131, 2006.
DOI : 10.1007/978-1-4615-6764-6

C. Burel, T. Boujard, A. Escaffre, S. Kaushik, G. Boeuf et al., Dietary low-glucosinolate rapeseed meal affects thyroid status and nutrient utilization in rainbow trout (Oncorhynchus mykiss), British Journal of Nutrition, vol.125, issue.06, pp.653-664, 2000.
DOI : 10.1079/NRR19940012

J. Cameron and C. Myers, Rapeseed protein isolate Brevet n° 4418013; U.S. Classification: 530/377. International Classification: A23J 114, 1983.

R. Carlson, Design of Experiments, Principles and Applications, L. Eriksson, E. Johansson, N. Kettaneh- Wold, C. Wikstr???m and S. Wold, Umetrics AB, Ume??? Learnways AB, Stockholm, 2000, ISBN 91-973730-0-1, xii?+?329 pp., Journal of Chemometrics, vol.15, issue.5, pp.495-496, 2001.
DOI : 10.1002/cem.686

G. Chabanon, A. Da-costa, L. Farges, B. Harscoat, C. Chenu et al., Influence of the rapeseed protein hydrolysis process on CHO cell growth, Bioresource Technology, vol.99, issue.15, 2008.
DOI : 10.1016/j.biortech.2007.12.070

URL : https://hal.archives-ouvertes.fr/hal-00301343

G. Chabanon, I. Chevalot, X. Framboisier, S. Chenu, and I. Marc, Hydrolysis of rapeseed protein isolates: Kinetics, characterization and functional properties of hydrolysates, Process Biochemistry, vol.42, issue.10, pp.1419-1428, 2007.
DOI : 10.1016/j.procbio.2007.07.009

URL : https://hal.archives-ouvertes.fr/hal-00277822

Z. Chen, C. Peng, R. Jiao, Y. Wong, Y. N. Huang et al., Anti-hypertensive Nutraceuticals and Functional Foods, Journal of Agricultural and Food Chemistry, vol.57, issue.11, pp.4485-4499, 2009.
DOI : 10.1021/jf900803r

J. Chobert, C. Bertrand-harb, and M. Nicolas, Solubility and emulsifying properties of caseins and whey proteins modified enzymically by trypsin, Journal of Agricultural and Food Chemistry, vol.36, issue.5, pp.883-892, 1988.
DOI : 10.1021/jf00083a002

J. Chobert, L. Briand, J. Guéguen, Y. Popineau, C. Larré et al., Recent advances in enzymatic modifications of food proteins for improving their functional properties, Food / Nahrung, vol.17, issue.4, 1996.
DOI : 10.1271/bbb1961.44.1567

A. Clemente, Enzymatic protein hydrolysates in human nutrition, Trends in Food Science & Technology, vol.11, issue.7, pp.254-262, 2000.
DOI : 10.1016/S0924-2244(01)00007-3

A. Clemente, J. Vioque, R. Sánchez-vioque, J. Pedroche, J. Bautista et al., Protein quality of chickpea (Cicer arietinum L.) protein hydrolysates, Food Chemistry, vol.67, issue.3, pp.269-274, 1999.
DOI : 10.1016/S0308-8146(99)00130-2

L. Coelho, Gaussian quantum-behaved particle swarm optimization approaches for constrained engineering design problems, Expert Systems with Applications, vol.37, issue.2, pp.1676-1683, 2010.
DOI : 10.1016/j.eswa.2009.06.044

L. Conejero, F. Sánchez-ruiz, P. Mateo, F. Burgos, J. Vendrell et al., Differential scanning calorimetric study of carboxypeptidase B, procarboxypeptidase B and its globular activation domain, European Journal of Biochemistry, vol.33, issue.3, pp.663-670, 1991.
DOI : 10.1002/bip.1978.360170212

A. Cooper, Heat capacity of hydrogen-bonded networks: an alternative view of protein folding thermodynamics, Biophysical Chemistry, vol.85, issue.1, pp.25-39, 2000.
DOI : 10.1016/S0301-4622(00)00136-8

C. Cui, X. Zhou, M. Zhao, and B. Yang, Effect of thermal treatment on the enzymatic hydrolysis of chicken proteins, Innovative Food Science & Emerging Technologies, vol.10, issue.1, pp.37-41, 2009.
DOI : 10.1016/j.ifset.2008.09.003

M. Dalgalarrondo, Contribution à l'étude des caractéristiques physico-chimiques des protéines des graines de Tournesol (Hélianthus annuus L.) et de Colza, 1986.

S. Damodaran, Protein Stabilization of Emulsions and Foams, Journal of Food Science, vol.59, issue.3, pp.54-66, 2005.
DOI : 10.1106/108201302028554

D. Souza, C. Pinto, M. Pelegrini, P. Lima, T. Silva et al., Plant storage proteins with antimicrobial activity: novel insights into plant defense mechanisms, The FASEB Journal, vol.25, issue.10, pp.3290-3305, 2011.

G. Deléage and C. Geourjon, An interactive graphic program for calculating the secondary structure content of proteins from circular dichroism spectrum, Bioinformatics, vol.9, issue.2, pp.197-199, 1993.
DOI : 10.1093/bioinformatics/9.2.197

J. Dewulf, H. Van-langenhove, and B. Van-de-velde, Exergy-Based Efficiency and Renewability Assessment of Biofuel Production, Environmental Science & Technology, vol.39, issue.10, pp.3878-3882, 2005.
DOI : 10.1021/es048721b

A. Dietz, C. Azzaro-pantel, L. Pibouleau, and S. Domenech, Multiobjective optimization for multiproduct batch plant design under economic and environmental considerations, Computers & Chemical Engineering, vol.30, issue.4, pp.599-613, 2006.
DOI : 10.1016/j.compchemeng.2005.10.017

URL : https://hal.archives-ouvertes.fr/hal-00475997

R. Froidevaux, F. Krier, N. Nedjar-arroume, D. Vercaigne-marko, E. Kosciarz et al., Antibacterial activity of a pepsin-derived bovine hemoglobin fragment, FEBS Letters, vol.49, issue.1-2, pp.159-163, 2001.
DOI : 10.1146/annurev.mi.49.100195.001425

URL : https://hal.archives-ouvertes.fr/hal-00280593

A. Geoffrion, J. Dyer, and A. Feinberg, An Interactive Approach for Multi-Criterion Optimization, with an Application to the Operation of an Academic Department, Management Science, vol.19, issue.4-part-1, pp.357-368, 1972.
DOI : 10.1287/mnsc.19.4.357

A. Ghodsvali, M. Khodaparast, M. Vosoughi, and L. Diosady, Preparation of canola protein materials using membrane technology and evaluation of meals functional properties, Food Research International, vol.38, issue.2, pp.223-231, 2005.
DOI : 10.1016/j.foodres.2004.10.007

I. Gill, R. Lopez-fandino, X. Jorba, and E. Vulfson, Biologically active peptides and enzymatic approaches to their production, Enzyme and Microbial Technology, vol.18, issue.3, pp.162-183, 1996.
DOI : 10.1016/0141-0229(95)00097-6

G. Godon, Protéines végétales, Eds Lavoisier, 1996.

D. Goldberg and J. Holland, Genetic Algorithms and Machine Learning, Machine Learning, vol.3, issue.2/3, pp.95-99, 1988.
DOI : 10.1023/A:1022602019183

D. Goldberg and M. Samtni, Engineering optimization via the genetic algorithms, Computers and Structures, vol.40, pp.1321-1327, 1991.

G. Graser, N. Oldham, P. Brown, U. Temp, and J. Gershenzon, The biosynthesis of benzoic acid glucosinolate esters in Arabidopsis thaliana, Phytochemistry, vol.57, issue.1, pp.23-32, 2001.
DOI : 10.1016/S0031-9422(00)00501-X

V. Grinberg, T. Burova, T. Haertlé, and V. Tolstoguzov, Interpretation of DSC data on protein denaturation complicated by kinetic and irreversible effects, Journal of Biotechnology, vol.79, issue.3, pp.269-280, 2000.
DOI : 10.1016/S0168-1656(00)00243-1

L. Gruener and M. Ismond, Effects of acetylation and succinylation on the functional properties of the canola 12S globulin, Food Chemistry, vol.60, issue.4, pp.513-520, 1997.
DOI : 10.1016/S0308-8146(97)00016-2

F. Gunstone, Production and consumption of rapeseed oil on a global scale, European Journal of Lipid Science and Technology, vol.6, issue.7, pp.447-449, 2001.
DOI : 10.5650/jos.50.269

X. Guo, T. Shaojun, and D. Small, Generation of meat-like flavourings from enzymatic hydrolysates of proteins from Brassica sp., Food Chemistry, vol.119, issue.1, pp.167-172, 2010.
DOI : 10.1016/j.foodchem.2009.05.089

J. Hamada, Effects of heat and proteolysis on deamidation of food proteins using peptidoglutaminase, Journal of Agricultural and Food Chemistry, vol.40, issue.5, pp.719-723, 1992.
DOI : 10.1021/jf00017a003

T. Higgins, D. Spencer, H. Dove, M. Freer, and J. Coombe, Rumen degradation of individual proteins in oil seeds and legume grains, Proceedings of the Nutrition Society of Australia, 1985.

C. Hsieh, F. Yang, and E. Iannotti, The effect of soy protein hydrolyzates on fermentation by Lactobacillus amylovorus, Process Biochemistry, vol.34, issue.2, pp.173-179, 1999.
DOI : 10.1016/S0032-9592(98)00081-8

A. Huang, Oleosins and Oil Bodies in Seeds and Other Organs, Plant Physiology, vol.110, issue.4, pp.1055-1061, 1996.
DOI : 10.1104/pp.110.4.1055

C. Huang, W. Liang, S. Lin, T. Tseng, and H. Chiang, A rough set based approach to patent development with the consideration of resource allocation, Expert Systems with Applications, vol.38, issue.3, pp.1980-1992, 2011.
DOI : 10.1016/j.eswa.2010.07.132

B. Hudson, New and Developing Sources of Food Proteins, 1994.
DOI : 10.1007/978-1-4615-2652-0

A. Jang and M. Lee, Purification and identification of angiotensin converting enzyme inhibitory peptides from beef hydrolysates, Meat Science, vol.69, issue.4, pp.653-661, 2005.
DOI : 10.1016/j.meatsci.2004.10.014

T. Jyothi, S. Singh, and A. Rao, ) in Salts and Monohydric Alcohols:?? Contribution of Electrostatic and Hydrophobic Interactions, Journal of Agricultural and Food Chemistry, vol.55, issue.10, pp.4229-4236, 2007.
DOI : 10.1021/jf0700935

R. Kapel, F. Klingenberg, X. Framboisier, P. Dhulster, and I. Marc, An original use of size exclusion-HPLC for predicting the performances of batch ultrafiltration implemented to enrich a complex protein hydrolysate in a targeted bioactive peptide, Journal of Membrane Science, vol.383, issue.1-2, pp.26-34, 2011.
DOI : 10.1016/j.memsci.2011.08.025

URL : https://hal.archives-ouvertes.fr/hal-00777705

R. Kapel, E. Rahhou, D. Lecouturier, D. Guillochon, and P. Dhulster, Characterization of an antihypertensive peptide from an Alfalfa white protein hydrolysate produced by a continuous enzymatic membrane reactor, Process Biochemistry, vol.41, issue.9, pp.1961-1966, 2006.
DOI : 10.1016/j.procbio.2006.04.019

K. Keen and N. Rapson, Development of a serum-free culture medium for the large scale production of recombinant protein from a Chinese hamster ovary cell line, Cytotechnology, vol.5, issue.7, pp.153-163, 1995.
DOI : 10.1007/BF00749653

S. Kelly and N. Price, The Use of Circular Dichroism in the Investigation of Protein Structure and Function, Current Protein & Peptide Science, vol.1, issue.4, pp.349-384, 2000.
DOI : 10.2174/1389203003381315

S. Kelly, T. Jess, and N. Price, How to study proteins by circular dichroism, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol.1751, issue.2, pp.1751-119, 2005.
DOI : 10.1016/j.bbapap.2005.06.005

A. Kilara and D. Panyam, Peptides From Milk Proteins and Their Properties, Critical Reviews in Food Science and Nutrition, vol.36, issue.6, pp.607-633, 2003.
DOI : 10.1016/0014-5793(95)00974-E

J. Kim, S. Park, I. Hwang, H. Cheong, J. Nah et al., Protease Inhibitors from Plants with Antimicrobial Activity, International Journal of Molecular Sciences, vol.44, issue.6, pp.2860-2872, 2009.
DOI : 10.1016/j.bbrc.2005.03.057

J. Kinsella, Advances in Food and Nutrition Research, 1989.

H. Kristinsson and B. Rasco, ) Muscle Proteins Hydrolyzed with Various Alkaline Proteases, Journal of Agricultural and Food Chemistry, vol.48, issue.3, pp.657-666, 2000.
DOI : 10.1021/jf990447v

J. Kroll, M. Kujawa, and W. Schnaak, Preparation of Rapeseed Proteins by Extraction, Ultrafiltration and Diafiltration, Fett Wissenschaft Technologie/Fat Science Technology, vol.27, issue.2, pp.61-65, 1991.
DOI : 10.1016/S0315-5463(88)70979-7

A. Kumoro, S. Sofiah, N. Aini, D. Retnowati, and C. Budiyati, EFFECT OF TEMPERATURE AND PARTICLE SIZE ON THE ALKALINE EXTRACTION OF PROTEIN FROM CHICKEN BONE WASTE, Reaktor, vol.13, issue.2, pp.124-130, 2012.
DOI : 10.14710/reaktor.13.2.124-130

A. Kunst, Enzymatic modification of soy proteins to improve their functional propertie, Industrial Proteins, vol.8, issue.3, pp.9-11, 2000.

M. Lacroix, J. Amiot, and G. Brisson, Hydrolysis and Ultrafiltration Treatment to Improve the Nutritive Value of Rapeseed Proteins, Journal of Food Science, vol.45, issue.1, pp.1644-1645, 1983.
DOI : 10.1111/j.1365-2621.1983.tb05050.x

U. Laemmli, Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4, Nature, vol.244, issue.5259, pp.680-685, 1970.
DOI : 10.1101/SQB.1963.028.01.053

J. Lahl, W. Lahl, and D. Braun, Enzymatic production of protein hydrolysates for food use, Food technology (Chicago), vol.48, issue.10, pp.68-71, 1994.

E. Lati, C. Dauphin, M. Hamon, and M. Silvestre, Comportement de m??langes d'acides amin??s et de peptides vis-??-vis du cuivre(II), Analytica Chimica Acta, vol.268, issue.1, 1992.
DOI : 10.1016/0003-2670(92)85260-D

S. Lee, M. Shimizu, S. Kaminogawa, and K. Yamauchi, Emulsifying Properties of Peptides Obtained from the Hydrolyzates of ?-Casein (Food & Nutrition), Agricultural and Biological Chemistry, vol.51, issue.1, pp.161-166, 1987.

J. Lemarié, D. Looze, M. Rivaud, and D. , Protéines de colza: quels usages industriels?, Oleoscope, vol.36, pp.9-18, 1996.

L. Lemieux, J. Piot, D. Guillochon, and J. Amiot, Study of the efficiency of a mobile phase used in size-exclusion HPLC for the separation of peptides from a casein hydrolysate according to their hydrodynamic volume, Chromatographia, vol.250, issue.11-12, pp.499-504, 1991.
DOI : 10.1007/BF02327894

J. Lepock, A. Rodahl, C. Zhang, M. Heynen, B. Waters et al., Thermal denaturation of the calcium ATPase of sarcoplasmic reticulum reveals two thermodynamically independent domains, Biochemistry, vol.29, issue.3, pp.681-689, 1990.
DOI : 10.1021/bi00455a013

O. Leprince, A. Van-aelst, H. Pritchard, and D. Murphy, Oleosins prevent oil-body coalescence during seed imbibition as suggested by a low-temperature scanning electron microscope study of desiccation-tolerant and -sensitive oilseeds, Planta, vol.204, issue.1, pp.109-119, 1997.
DOI : 10.1007/s004250050236

I. Liener, Implications of antinutritional components in soybean foods, Critical Reviews in Food Science and Nutrition, vol.50, issue.1, pp.31-67, 1994.
DOI : 10.1271/bbb.56.978

P. Lin and T. Ng, A novel and exploitable antifungal peptide from kale (Brassica alboglabra) seeds, Peptides, vol.29, issue.10, pp.1664-1671, 2008.
DOI : 10.1016/j.peptides.2008.05.020

Y. Ma and Y. Xiong, Antioxidant and Bile Acid Binding Activity of Buckwheat Protein in Vitro Digests, Journal of Agricultural and Food Chemistry, vol.57, issue.10, pp.4372-4380, 2009.
DOI : 10.1021/jf803670u

L. Magalas and T. Malinowski, A New Multifunctional Subresonant and Resonant Mechanical Spectrometer, Solid State Phenomena, vol.89, pp.349-354, 2003.
DOI : 10.4028/www.scientific.net/SSP.89.349

M. Mahmoud, Physicochemical and functional properties of protein hydrosylates in nutritional products, Food technology, vol.48, pp.89-95, 1994.

J. Maldonado, A. Gill, E. Narbona, A. Molina, R. Bayers et al., Special formulas in infant nutrition: a review, Early Human Development, vol.53, pp.23-32, 1998.
DOI : 10.1016/S0378-3782(98)00062-0

S. Mandal, P. Kundu, B. Roy, and R. Mandal, Is a Novel Trypsin Inhibitor, Journal of Biological Chemistry, vol.55, issue.40, pp.37161-37168, 2002.
DOI : 10.1016/S0168-9452(00)00358-7

A. Mannheim and M. Cheryan, Continuous Hydrolysis of Milk Protein in a Membrane Reactor, Journal of Food Science, vol.62, issue.9, pp.381-385, 1990.
DOI : 10.1021/ba-1977-0160.ch005

S. Maouche, C. Bounsaythip, and G. Roussel, Optimisation du placement des formes irrégulières, pp.7212-7213, 2000.

A. Margot, E. Flaschel, and A. Renken, Empirical kinetic models for tryptic whey-protein hydrolysis, Process Biochemistry, vol.32, issue.3, pp.217-223, 1997.
DOI : 10.1016/S0032-9592(96)00060-X

G. Mariscal-landín, R. Souza, T. Parra, J. Aguilera, A. Mar et al., Ileal digestibility of protein and amino acids from canola meal in weaned piglets and growing pigs, Livestock Science, vol.116, issue.1-3, pp.53-62, 2008.
DOI : 10.1016/j.livsci.2007.08.008

S. Massebeuf, C. Fonteix, S. Hoppe, and F. Pla, Development of new concepts for the control of polymerization processes: Multiobjective optimization and decision engineering. I. Application to emulsion homopolymerization of styrene, Journal of Applied Polymer Science, vol.75, issue.14, pp.2383-2396, 2003.
DOI : 10.1016/S1385-8947(98)00116-8

URL : https://hal.archives-ouvertes.fr/hal-01630393

M. Kevith and B. , British Nutrition Foundation, Nutrition Bulletin, vol.30, pp.13-26, 2005.

H. Meisel, Biochemical properties of regulatory peptides derived from mil proteins, Biopolymers, vol.45, issue.2, pp.119-128, 1997.
DOI : 10.4327/jsnfs.45.513

R. Monsalve and R. Rodriguez, Purification and Characterization of Proteins from the 2S Fraction from Seeds of the Brassicaceae Family, Journal of Experimental Botany, vol.41, issue.1, pp.89-94, 1990.
DOI : 10.1093/jxb/41.1.89

R. Monsalve, M. Villalba, C. López-otín, and R. Rodríguez, Structural analysis of the small chain of the 2S albumin, napin nIII, from rapeseed. Chemical and spectroscopic evidence of an intramolecular bond formation, Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol.1078, issue.2, pp.265-272, 1991.
DOI : 10.1016/0167-4838(91)90568-K

A. Morato and R. Junqueira, Optimization of Casein Hydrolysis for Obtaining High Contents of Small Peptides: Use of Subtilisin and Trypsin, Journal of Food Composition and Analysis, vol.13, issue.5, pp.843-857, 2000.
DOI : 10.1006/jfca.2000.0912

F. Moreno, F. Mellon, M. Wickham, A. Bottrill, and E. Mills, Stability of the major allergen Brazil nut 2S albumin (Ber e 1) to physiologically relevant in vitro gastrointestinal digestion, FEBS Journal, vol.43, issue.S, pp.341-352, 2005.
DOI : 10.1021/bi0496900

A. Moure, J. Sineiro, H. Dominguez, and J. Parajò, Functionality of oilseed protein products: A review, Food Research International, vol.39, issue.9, pp.945-963, 2006.
DOI : 10.1016/j.foodres.2006.07.002

M. Mullally, O. Callaghan, D. Fitzgerald, R. Donnelly, W. Dalton et al., Proteolytic and Peptidolytic Activities in Commercial Pancreatic Protease Preparations and Their Relationship to Some Whey Protein Hydrolyzate Characteristics, Journal of Agricultural and Food Chemistry, vol.42, issue.12, pp.2973-2981, 1994.
DOI : 10.1021/jf00048a062

L. Muniglia, N. Kiss, L. Fonteix, C. Marc, and I. , Multicriteria optimization of a single-cell oil production, European Journal of Operational Research, vol.153, issue.2, pp.360-369, 2004.
DOI : 10.1016/S0377-2217(03)00158-9

E. Murén, B. Ek, and L. Rask, Processing of the 2S Storage Protein Pronapin in Brassica napus and in Transformed Tobacco, European Journal of Biochemistry, vol.76, issue.1-2, pp.316-321, 2005.
DOI : 10.1016/S0015-3796(89)80052-6

E. Murén, B. Ek, I. Björk, and L. Rask, Structural Comparison of the Precursor and the Mature Form of Napin, the 2S Storage Protein in Brassica napus, European Journal of Biochemistry, vol.43, issue.2, pp.214-219, 2004.
DOI : 10.1006/abio.1993.1079

R. Myers, D. Montgomery, and C. Anderson-cook, Response Surface Methodology: Process and Product Optimization Using Designed Experiments, 2009.

M. Naczk, R. Amarowicz, A. Sullivan, and . Shahidi, Current research developments on polyphenolics of rapeseed/canola: a review, Food Chemistry, vol.62, issue.4, pp.489-502, 1997.
DOI : 10.1016/S0308-8146(97)00198-2

N. Nedjar-arroume, V. Dubois-delval, E. Adje, J. Traisnel, F. Krier et al., Bovine hemoglobin: An attractive source of antibacterial peptides, Peptides, vol.29, issue.6, pp.29-969, 2008.
DOI : 10.1016/j.peptides.2008.01.011

N. Nelson, A photometric adaptation of the Somogyi method for determination of glucose, Journal of Biologica Chemistry, issue.153, pp.375-380, 1944.

G. Neumann, R. Condron, I. Thomas, and G. Polya, Purification and sequencing of multiple forms of Brassica napus seed napin small chains that are calmodulin antagonists and substrates for plant calcium-dependent protein kinase, BBA) Protein Structure and Molecular Enzymology1295, pp.23-33, 1996.
DOI : 10.1016/0167-4838(96)00006-4

G. Neumann, R. Condron, and G. Polya, Purification and sequencing of yellow mustard seed napin small and large chains that are phosphorylated by plant calcium-dependent protein kinase and are calmodulin antagonists, Plant Science, vol.119, issue.1-2, pp.49-66, 1996.
DOI : 10.1016/0168-9452(96)04476-7

&. Ngaiphk, A napin-like polypeptide from dwarf Chinese white cabbage seeds with translation-inhibitory, trypsin-inhibitory, and antibacterial activities, Peptides, vol.25, issue.2, pp.171-176, 2004.

P. Nielsen, D. Petersen, and C. Dambmann, Improved Method for Determining Food Protein Degree of Hydrolysis, Journal of Food Science, vol.29, issue.4, pp.642-646, 2001.
DOI : 10.1002/jctb.280340311

O. Oniol, Conseil de direction du 16-11, 2005.

C. Pace, D. Laurents, and J. Thomson, pH dependence of the urea and guanidine hydrochloride denaturation of ribonuclease A and ribonuclease T1, Biochemistry, vol.29, issue.10, pp.2564-2572, 1990.
DOI : 10.1021/bi00462a019

M. Pande, N. Kumari, V. Dubey, P. Tripathi, and M. Jagannadham, Stability and unfolding studies on alkaline denatured state (Ip) of pepsin, Process Biochemistry, vol.44, issue.8, pp.906-911, 2009.
DOI : 10.1016/j.procbio.2009.04.016

C. Parker, Photoluminescence of solutions: With applications to photochemistry and analytical chemistry, 1968.

D. Parmenter, J. Boothe, G. Rooijen, E. Yeung, and M. Moloney, Production of biologically active hirudin in plant seeds using oleosin partitioning, Plant Molecular Biology, vol.95, issue.6, pp.1167-1180, 1995.
DOI : 10.1007/BF00020460

Z. Pawlak, ROUGH SET THEORY AND ITS APPLICATIONS TO DATA ANALYSIS, Cybernetics and Systems, vol.29, issue.7, pp.661-688, 1998.
DOI : 10.1080/019697298125470

B. Pedersen, Removing bitterness from protein hydrolysates, Food Technology, vol.48, issue.10, pp.96-76, 1994.

J. Pedroche, M. Yust, H. Lqari, J. Girón-calle, M. Alaiz et al., Brassica carinata protein isolates: chemical composition, protein characterization and improvement of functional properties by protein hydrolysis, Food Chemistry, vol.88, issue.3, pp.337-346, 2004.
DOI : 10.1016/j.foodchem.2004.01.045

A. Perea and U. Ugalde, Continuous hydrolysis of whey proteins in a membrane recycle reactor, Enzyme and Microbial Technology, vol.18, issue.1, pp.29-34, 1996.
DOI : 10.1016/0141-0229(96)00046-4

E. Perrin, A. Mandrille, M. Oumoun, C. Fonteix, and . Marc, Optimisation globale par stratégie d'évolution. Technique utilisant la génétique des individus diploïdes, RAIRO. Recherche opérationnelle, issue.2, pp.31-161, 1997.

R. Philips and L. Beuchat, Enzyme Modification of Proteins, ACS Symp. Ser, vol.147, pp.275-298, 1981.
DOI : 10.1021/bk-1981-0147.ch013

P. Plietz, G. Damaschun, J. Müller, and K. Schwenke, The Structure of 11-S Globulins from Sunflower and Rape Seed. A Small-Angle X-Ray Scattering Study, European Journal of Biochemistry, vol.175, issue.2, pp.315-320, 1983.
DOI : 10.1016/S0015-3796(80)80019-9

J. Powers and R. Hancock, The relationship between peptide structure and antibacterial activity, Peptides, vol.24, issue.11, pp.1681-1691, 2003.
DOI : 10.1016/j.peptides.2003.08.023

P. Privalov, Stability of Proteins Small Globular Proteins, Advances in Protein, vol.33, pp.167-241, 1979.
DOI : 10.1016/S0065-3233(08)60460-X

P. Privalov, Energy characteristics of the structure of protein molecules, Biofizika, vol.30, issue.4, pp.722-733, 1985.

G. Rakow, Species Origin and Economic Importance of Brassica, Biotechnology in Agriculture and Forestry, pp.3-12, 2004.
DOI : 10.1007/978-3-662-06164-0_1

Z. Randriamahatody, K. Sylla, H. Nguyen, C. Donnay-moreno, L. Razanamparany et al., Proteolysis of shrimp by-products (Peaneus monodon) from, 2011.

M. Regente and L. De-la-canal, Do sunflower 2S albumins play a role in resistance to fungi?, Plant Physiology and Biochemistry, vol.39, issue.5, pp.407-413, 2001.
DOI : 10.1016/S0981-9428(01)01256-6

Z. Rehman and W. Shah, Thermal heat processing effects on antinutrients, protein and starch digestibility of food legumes, Food Chemistry, vol.91, issue.2, pp.327-331, 2005.
DOI : 10.1016/j.foodchem.2004.06.019

S. Ribeiro, . Almeidarg, C. Pereira, J. Moreira, M. Pinto et al., Identification of a Passiflora alata Curtis dimeric peptide showing identity with 2S albumins, Peptides, vol.32, issue.5, pp.868-874, 2010.
DOI : 10.1016/j.peptides.2010.10.011

S. Ribeiro, A. Carvalho, D. Cunha, M. Rodrigues, R. Cruz et al., Isolation and characterization of novel peptides from chilli pepper seeds: Antimicrobial activities against pathogenic yeasts, Toxicon, vol.50, issue.5, pp.600-611, 2007.
DOI : 10.1016/j.toxicon.2007.05.005

I. Rodrigues, J. Coelho, and M. Carvalho, Isolation and valorisation of vegetable proteins from oilseed plants: Methods, limitations and potential, Journal of Food Engineering, vol.109, issue.3, pp.337-346, 2011.
DOI : 10.1016/j.jfoodeng.2011.10.027

J. Rupley, L. Butler, M. Gerring, F. Hartdegen, and R. Pecoraro, Studies on the enzymic activity of lysozyme, 3. The binding of saccharides., Proceedings of the National Academy of Sciences, vol.57, issue.4, pp.1088-1095, 1967.
DOI : 10.1073/pnas.57.4.1088

. Sallehmrbm, N. Maruyama, M. Adachi, N. Hontani, S. Saka et al., Comparison of protein chemical and physicochemical properties of rapeseed cruciferin with those of soybean glycinin, Journal of Agricultural and Food Chemistry, vol.50, issue.25, pp.7380-7385, 2002.

D. Salunke, R. Adsule, J. Chavan, and S. Kadam, World Oilseeds, 1992.

C. Sandiford, A. Tatham, R. Fido, J. Welch, M. Jones et al., Identification of the major water/salt insoluble wheat proteins involved in cereal hypersensitivity, Clinical & Experimental, issue.10, pp.27-1120, 1997.

D. Sarkar and J. Modak, Genetic algorithms with filters for optimal control problems in fed-batch bioreactors, Bioprocess and Biosystems Engineering, vol.58, issue.4/5, pp.295-306, 2004.
DOI : 10.1007/s00449-004-0366-0

D. Sarkar and J. Modak, Optimization of fed-batch bioreactors using genetic algorithm: multiple control variables, Computers & Chemical Engineering, vol.28, issue.5, pp.789-798, 2004.
DOI : 10.1016/j.compchemeng.2004.02.018

S. Sathe, Dry Bean Protein Functionality, Critical Reviews in Biotechnology, vol.182, issue.9, pp.175-223, 2002.
DOI : 10.1126/science.182.4115.887

D. Schaffer, Multiple Objective Optimization with Vector Evaluated Genetic Algorithms, 1985.

M. Schweizer, Fractionnement et identification de petits peptides issus de l'hydrolyse enzymatique des protéines de colza, 2002.

K. Schwenke, Structural studies on native and chemically modified storage proteins from rapeseed (Brassica napus L.) and related plant proteins, Food / Nahrung, vol.16, issue.3, pp.225-240, 1990.
DOI : 10.1042/bst0150684

K. Schwenke, R. Mothes, S. Dudek, and E. Görnitz, ) by Phosphorous Oxychloride:?? Chemical and Conformational Aspects, Journal of Agricultural and Food Chemistry, vol.48, issue.3, pp.708-715, 2000.
DOI : 10.1021/jf9907900

F. Shahidi, Canola and rapeseed: production, chemistry, nutrition, and processing technology, 1990.
DOI : 10.1007/978-1-4615-3912-4

F. Shahidi and M. Naczk, An overview of the phenolics of canola and rapeseed: Chemical, sensory and nutritional significance, Journal of the American Oil Chemists' Society, vol.13, issue.9, pp.917-924, 1992.
DOI : 10.1007/BF01020552

L. Shen, X. Wang, Z. Wang, Y. Wu, and J. Chen, Studies on tea protein extraction using alkaline and enzyme methods, Food Chemistry, vol.107, issue.2, pp.929-938, 2008.
DOI : 10.1016/j.foodchem.2007.08.047

. Shewrypr and N. Halford, Cereal seed storage proteins: structures, properties and role in grain utilization, Journal of Experimental, vol.53370, pp.947-958, 2002.

C. Silva and E. Biscaia, Genetic algorithm development for multi-objective optimization of batch free-radical polymerization reactors, Computers & Chemical Engineering, vol.27, issue.8-9, pp.1329-1344, 2003.
DOI : 10.1016/S0098-1354(03)00056-5

M. Silvestre, Review of methods for the analysis of protein hydrolysates, Food Chemistry, vol.60, issue.2, pp.263-271, 1996.
DOI : 10.1016/S0308-8146(96)00347-0

. Silvestrempc, M. Hamon, and M. Yvon, Analysis of Protein Hydrolyzates. 1. Use of Poly(2-hydroxyethylaspartamide)-Silica Column in Size Exclusion Chromatography for the Fractionation of Casein Hydrolyzates, Journal of Agricultural and Food Chemistry, vol.42, issue.12, pp.2778-2782, 1994.
DOI : 10.1021/jf00048a024

C. Simard, Y. Dupont, and M. Boulet, Propriétés physicochimiques et composition en acides aminés de fractions de protéines de soja, de fèverole,de colza et de feuille e luzerne, AGRICOLA, the online catalog of the National Agricultural, pp.326-330, 1977.

E. Smacchi and M. Gobbetti, Bioactive peptides in dairy products: synthesis and interaction with proteolytic enzymes, Food Microbiology, vol.17, issue.2, pp.129-141, 2000.
DOI : 10.1006/fmic.1999.0302

D. Spellman, E. Mcevoy, G. O-'cuinn, and R. Fitzgerald, Proteinase and exopeptidase hydrolysis of whey protein: Comparison of the TNBS, OPA and pH stat methods for quantification of degree of hydrolysis, International Dairy Journal, vol.13, issue.6, pp.447-453, 2003.
DOI : 10.1016/S0958-6946(03)00053-0

H. Stapelfeldt, P. Petersen, K. Kristiansen, K. Qvist, and L. Skibsted, Effect of high hydrostatic pressure on the enzymic hydrolysis of beta-lactoglobulin B by trypsin, thermolysin and pepsin, The Journal of Dairy, vol.631, pp.111-118, 1996.

H. Steinhardt and S. Beychok, Interaction of protein with hydrogen ions and other small ions and molecules. Dans: The Protein, pp.139-304, 1964.

K. Tan, E. Khor, T. Lee, and Y. Yang, A Tabu-Based Exploratory Evolutionary Algorithm for Multiobjective Optimization, Artificial Intelligence Review, vol.19, issue.3, pp.231-260, 2003.
DOI : 10.1023/A:1022863019997

F. Terras, H. Schoofs, K. Thevissen, R. Osborn, J. Vanderleyden et al., Synergistic Enhancement of the Antifungal Activity of Wheat and Barley Thionins by Radish and Oilseed Rape 2S Albumins and by Barley Trypsin Inhibitors, Plant Physiology, vol.103, issue.4, pp.1311-1319, 1993.
DOI : 10.1104/pp.103.4.1311

F. Terras, S. Torrekens, F. Van-leuven, R. Osborn, J. Vanderleyden et al., A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species, FEBS Letters, vol.93, issue.3, pp.233-240, 1993.
DOI : 10.1104/pp.93.2.522

B. Tessier, C. Harscoat-schiavo, and I. Marc, L.) Protein Hydrolysate Using UF/NF Membranes, Journal of Agricultural and Food Chemistry, vol.54, issue.10, pp.3578-3584, 2006.
DOI : 10.1021/jf0527605

URL : https://hal.archives-ouvertes.fr/cirad-00180360

M. Torp and H. Niremberg, Fusarium langsethiae sp. nov. on cereals in Europe, International Journal of Food Microbiology, vol.95, issue.3, pp.247-256, 2004.
DOI : 10.1016/j.ijfoodmicro.2003.12.014

A. Tossi, L. Sandri, and A. Giangaspero, Amphipathic, ??-helical antimicrobial peptides, Biopolymers, vol.57, issue.1, pp.4-30, 2000.
DOI : 10.1128/AAC.36.2.313

I. Trelea, M. Titica, and G. Corrieu, Dynamic optimisation of the aroma production in brewing fermentation, Journal of Process Control, vol.14, issue.1, pp.1-16, 2004.
DOI : 10.1016/S0959-1524(03)00007-6

URL : https://hal.archives-ouvertes.fr/hal-01537106

S. Turgeon, S. Gauthier, and P. Paquin, Interfacial and emulsifying properties of whey peptide fractions obtained with a two-step ultrafiltration process, Journal of Agricultural and Food Chemistry, vol.39, issue.4, pp.673-676, 1991.
DOI : 10.1021/jf00004a009

J. Tzen and H. Huang, Surface structure and properties of plant seed oil bodies, The Journal of Cell Biology, vol.117, issue.2, pp.327-335, 1992.
DOI : 10.1083/jcb.117.2.327

Y. Tzeng, L. Diosady, and J. Rubin, Production of Canola Protein Materials by Alkaline Extraction, Precipitation, and Membrane Processing, Journal of Food Science, vol.53, issue.1, pp.1147-1151, 1990.
DOI : 10.1016/S0315-5463(88)70979-7

F. Uruakpa and S. Arntfield, Emulsifying characteristics of commercial canola protein???hydrocolloid systems, Food Research International, vol.38, issue.6, pp.659-672, 2005.
DOI : 10.1016/j.foodres.2005.01.004

R. Viennet, C. Fonteix, and I. Marc, New multicriteria optimization method based on the use of a diploid genetic algorithm: Example of an industrial problem, Artificial Evolution, vol.1063, pp.120-127, 1996.
DOI : 10.1007/3-540-61108-8_34

J. Vioque, R. Sánchez-vioque, A. Clemente, J. Pedroche, and F. Millán, Partially hydrolyzed rapeseed protein isolates with improved functional properties, Journal of the American Oil Chemists' Society, vol.57, issue.4, pp.447-450, 2000.
DOI : 10.1111/j.1365-2621.1994.tb08207.x

U. Wanasundara, R. Amarowicz, and F. Shahidi, Isolation and Identification of an Antioxidative Component in Canola Meal, Journal of Agricultural and Food Chemistry, vol.42, issue.6, pp.1285-1290, 1994.
DOI : 10.1021/jf00042a006

C. Wang and S. Damodaran, Thermal gelation of globular proteins: influence of protein conformation on gel strength, Journal of Agricultural and Food Chemistry, vol.39, issue.3, pp.433-438, 1991.
DOI : 10.1021/jf00003a001

J. Wang, Z. Wei, L. Li, K. Bian, and M. Zhao, Characteristics of enzymatic hydrolysis of thermal-treated wheat gluten, Journal of Cereal Science, vol.50, issue.2, pp.205-209, 2009.
DOI : 10.1016/j.jcs.2009.05.004

D. Wolpert and W. Macready, No free lunch theorems for optimization, IEEE Transactions on Evolutionary Computation, vol.1, issue.1, pp.67-82, 1997.
DOI : 10.1109/4235.585893

J. Wu and A. Muir, Comparative structural, emulsifying, and biological properties, 2008.

J. Wu, R. Aluko, and A. Muir, Purification of angiotensin I-converting enzyme-inhibitory peptides from the enzymatic hydrolysate of defatted canola meal, Food Chemistry, vol.111, issue.4, pp.942-950, 2008.
DOI : 10.1016/j.foodchem.2008.05.009

L. Xu and L. Diosady, Functional Properties of Chinese Rapeseed Protein Isolates, Journal of Food Science, vol.53, issue.5, pp.1127-1130, 1994.
DOI : 10.1016/S0315-5463(86)71417-X

L. Xu and L. Diosady, The production of Chinese rapeseed protein isolates by membrane processing, Journal of the American Oil Chemists' Society, vol.24, issue.9, pp.935-939, 1994.
DOI : 10.1002/jsfa.2740240503

L. Xu and L. Diosady, Interactions between canola proteins and phenolic compounds in aqueous media, Food Research International, vol.33, issue.9, pp.725-731, 2000.
DOI : 10.1016/S0963-9969(00)00062-4

L. Xu and L. Diosady, Removal of phenolic compounds in the production of high-quality canola protein isolates, Food Research International, vol.35, issue.1, pp.23-30, 2002.
DOI : 10.1016/S0963-9969(00)00159-9

Z. Xue, W. Yu, Z. Liu, M. Wu, X. Kou et al., Preparation and Antioxidative Properties of a Rapeseed (Brassica napus) Protein Hydrolysate and Three Peptide Fractions, Journal of Agricultural and Food Chemistry, vol.57, issue.12, pp.57-5287, 2009.
DOI : 10.1021/jf900860v

Y. Yamada, M. Iwasaki, H. Usui, K. Ohinata, E. Marczak et al., Rapakinin, an anti-hypertensive peptide derived from rapeseed protein, dilates mesenteric artery of spontaneously hypertensive rats via the prostaglandin IP receptor followed by CCK1 receptor, Peptides, vol.31, issue.5, pp.31-909, 2010.
DOI : 10.1016/j.peptides.2010.02.013