F. Bernaudat, A. Frelet-barrand, N. Pochon, S. Dementin, P. Hivin et al., Heterologous Expression of Membrane Proteins: Choosing the Appropriate Host, PLoS ONE, vol.26, issue.12, p.29191, 2011.
DOI : 10.1371/journal.pone.0029191.s003

URL : https://hal.archives-ouvertes.fr/hal-00672578

L. Loir, Y. Azevedo, V. Oliveira, S. Freitas, D. Miyoshi et al., Protein secretion in Lactococcus lactis: an efficient way to increase the overall heterologous protein production, Microb Cell Fact, vol.4, issue.2, 2005.
URL : https://hal.archives-ouvertes.fr/hal-01453908

L. Westers, H. Westers, and W. Quax, Bacillus subtilis as cell factory for pharmaceutical proteins: a biotechnological approach to optimize the host organism, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1694, issue.1-3, pp.299-310, 2004.
DOI : 10.1016/j.bbamcr.2004.02.011

E. Morello, L. Bermudez-humaran, D. Llull, V. Sole, N. Miraglio et al., <i>Lactococcus lactis,</i> an Efficient Cell Factory for Recombinant Protein Production and Secretion, Journal of Molecular Microbiology and Biotechnology, vol.39, issue.1-3, pp.48-58, 2008.
DOI : 10.1007/BF00280397

M. Zhou, D. Theunissen, M. Wels, and R. Siezen, LAB-Secretome: a genome-scale comparative analysis of the predicted extracellular and surface-associated proteins of Lactic Acid Bacteria, BMC Genomics, vol.11, issue.1, p.651, 2010.
DOI : 10.1186/1471-2164-11-651

S. Wydau, R. Dervyn, J. Anba, S. Ehrlich, and E. Maguin, ssp., FEMS Microbiology Letters, vol.2, issue.1, pp.32-42, 2006.
DOI : 10.1111/j.1574-6968.2006.00141.x

O. Johnsborg, V. Eldholm, and L. Havarstein, Natural genetic transformation: prevalence, mechanisms and function, Research in Microbiology, vol.158, issue.10, pp.767-778, 2007.
DOI : 10.1016/j.resmic.2007.09.004

M. Elli, M. Callegari, S. Ferrari, E. Bessi, D. Cattivelli et al., Survival of Yogurt Bacteria in the Human Gut, Applied and Environmental Microbiology, vol.72, issue.7, pp.5113-5117, 2006.
DOI : 10.1128/AEM.02950-05

URL : https://hal.archives-ouvertes.fr/hal-00294424

D. Mater, L. Bretigny, O. Firmesse, M. Flores, A. Mogenet et al., survive gastrointestinal transit of healthy volunteers consuming yogurt, FEMS Microbiology Letters, vol.68, issue.2, pp.185-187, 2005.
DOI : 10.1016/j.femsle.2005.07.006

F. Guarner, G. Perdigon, G. Corthier, S. Salminen, B. Koletzko et al., Should yoghurt cultures be considered probiotic?, British Journal of Nutrition, vol.49, issue.06, pp.783-786, 2005.
DOI : 10.1016/S0168-1605(97)00136-0

D. Solaiman and G. Somkuti, Construction of a green-fluorescent proteinbased , insertion-inactivation shuttle vector for lactic acid bacteria and Escherichia coli of absolute protein amount in proteomics by the number of sequenced peptides per protein, Biotechnol Lett Mol Cell Proteomics, vol.19, issue.4, pp.1175-11791265, 1997.

J. Rappsilber, U. Ryder, A. Lamond, and M. Mann, Large-Scale Proteomic Analysis of the Human Spliceosome, Genome Research, vol.12, issue.8, pp.1231-1245, 2002.
DOI : 10.1101/gr.473902

J. Delcour, T. Ferain, M. Deghorain, E. Palumbo, and P. Hols, The biosynthesis and functionality of the cell-wall of lactic acid bacteria, Antonie Van Leeuwenhoek, vol.76, pp.159-184, 1999.
DOI : 10.1007/978-94-017-2027-4_7

K. Schleifer and O. Kandler, Peptidoglycan types of bacterial cell walls and their taxonomic implications, Bacteriol Rev, vol.36, pp.407-477, 1972.

C. Camacho, G. Coulouris, V. Avagyan, N. Ma, J. Papadopoulos et al., BLAST+: architecture and applications, BMC Bioinformatics, vol.10, issue.1, p.421, 2009.
DOI : 10.1186/1471-2105-10-421

N. Solis, M. Larsen, and S. Cordwell, Improved accuracy of cell surface shaving proteomics in Staphylococcus aureus using a false-positive control, PROTEOMICS, vol.284, issue.10, pp.2037-2049, 2010.
DOI : 10.1099/00221287-145-9-2497

A. Olaya-abril, L. Gomez-gascon, I. Jimenez-munguia, I. Obando, and M. Rodriguez-ortega, Another turn of the screw in shaving Gram-positive bacteria: Optimization of proteomics surface protein identification in Streptococcus pneumoniae, Journal of Proteomics, vol.75, issue.12, pp.3733-3746, 2012.
DOI : 10.1016/j.jprot.2012.04.037

B. Henderson and A. Martin, ABSTRACT, Infection and Immunity, vol.79, issue.9, pp.3476-3491, 2011.
DOI : 10.1128/IAI.00179-11

L. Marraffini, A. Dedent, and O. Schneewind, Sortases and the Art of Anchoring Proteins to the Envelopes of Gram-Positive Bacteria, Microbiology and Molecular Biology Reviews, vol.70, issue.1, pp.192-221, 2006.
DOI : 10.1128/MMBR.70.1.192-221.2006

S. Hu, J. Kong, Z. Sun, L. Han, W. Kong et al., Heterologous protein display on the cell surface of lactic acid bacteria mediated by the s-layer protein. Microb Cell Fact, p.86, 2011.

O. Chang, C. Perrin, W. Galia, F. Saulnier, L. Miclo et al., Release of the cell-envelope protease PrtS in the growth medium of Streptococcus thermophilus 4F44, International Dairy Journal, vol.23, issue.2, pp.91-98, 2012.
DOI : 10.1016/j.idairyj.2011.10.014

W. Galia, C. Perrin, M. Genay, and A. Dary, Variability and molecular typing of Streptococcus thermophilus strains displaying different proteolytic and acidifying properties, International Dairy Journal, vol.19, issue.2, pp.89-95, 2009.
DOI : 10.1016/j.idairyj.2008.08.004

K. Makarova, A. Slesarev, Y. Wolf, A. Sorokin, B. Mirkin et al., Comparative genomics of the lactic acid bacteria, Proceedings of the National Academy of Sciences, vol.29, issue.1, pp.15611-15616, 2006.
DOI : 10.1093/nar/29.1.22

B. Terzaghi and W. Sandine, Improved medium for lactic Streptococci and their bacteriophages, Appl Microbiol, vol.29, pp.807-813, 1975.

C. Letort and V. Juillard, Development of a minimal chemically-defined medium for the exponential growth of Streptococcus thermophilus, Journal of Applied Microbiology, vol.29, issue.6, pp.1023-1029, 2001.
DOI : 10.1007/s002530051569

M. Green and J. Sambrook, Molecular Cloning: A Laboratory Manual, 2012.

A. Untergasser, H. Nijveen, X. Rao, T. Bisseling, R. Geurts et al., Primer3Plus, an enhanced web interface to Primer3, Nucleic Acids Research, vol.35, issue.Web Server, pp.71-74, 2007.
DOI : 10.1093/nar/gkm306

E. Maguin, H. Prevost, S. Ehrlich, and A. Gruss, Efficient insertional mutagenesis in lactococci and other gram-positive bacteria., Journal of Bacteriology, vol.178, issue.3, pp.931-935, 1996.
DOI : 10.1128/jb.178.3.931-935.1996

M. Chopard, M. Schmitt, E. Perrerad, and J. Chamba, Aspect qualitatif de l'activit?? prot??olytique des lactobacilles thermophiles utilis??s en fabrication de fromages ?? p??te press??e cuite, Le Lait, vol.81, issue.1-2, pp.183-194, 2001.
DOI : 10.1051/lait:2001122

Y. Ardö and H. Pettersson, Accelerated cheese ripening with heat treated cells of Lactobacillus helveticus and a commercial proteolytic enzyme, Journal of Dairy Research, vol.49, issue.02, pp.239-245, 1988.
DOI : 10.1038/215351a0

H. J. Bartels, M. E. Johnson, and N. F. Olson, Accelerated ripening of Gouda cheese. 1. Effect of heat-shocked thermophilic lactobacilli and streptococci on proteolysis and flavor development, Milchwissenschaft, vol.42, pp.83-88, 1987.

H. J. Bartels, M. E. Johnson, and N. F. Olson, Accelerated ripening of Gouda cheese. 2. Effect of freeze-shocked Lactobacillus helveticus on proteolysis and flavor development, Milchwissenschaft, vol.42, pp.139-144, 1987.

P. Boyaval, C. Deborde, C. Corre, C. Blanco, and É. Bégué, Stress and osmoprotection in propionibacteria, Le Lait, vol.79, issue.1, pp.59-69, 1999.
DOI : 10.1051/lait:199914

URL : https://hal.archives-ouvertes.fr/hal-00929637

J. R. Broadbent, J. E. Hughes, D. L. Welker, T. A. Tompkins, and J. L. Steele, Complete Genome Sequence for Lactobacillus helveticus CNRZ 32, an Industrial Cheese Starter and Cheese Flavor Adjunct, Genome Announcements, vol.94, issue.9, pp.590-1300590, 2013.
DOI : 10.3168/jds.2010-4068

E. Cachat and F. G. Priest, Lactobacillus suntoryeus sp. nov., isolated from malt whisky distilleries, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol.55, issue.1, pp.31-34, 2005.
DOI : 10.1099/ijs.0.63266-0

URL : http://ijs.microbiologyresearch.org/deliver/fulltext/ijsem/55/1/31.pdf?itemId=/content/journal/ijsem/10.1099/ijs.0.63266-0&mimeType=pdf&isFastTrackArticle=

. Madden, BLAST plus : architecture and applications, BMC Bioinformatics, vol.10, p.421, 2009.

J. E. Christensen, J. R. Broadbent, and J. L. Steele, Hydrolysis of Casein-Derived Peptides ??S1-Casein(f1-9) and ??-Casein(f193-209) by Lactobacillus helveticus Peptidase Deletion Mutants Indicates the Presence of a Previously Undetected Endopeptidase, Applied and Environmental Microbiology, vol.69, issue.2, 2003.
DOI : 10.1128/AEM.69.2.1283-1286.2003

. Rolet-repecaud, Affinage et qualité du Gruyère de Comté. IV. Etude de la protéolyse, Lait -Dairy Sci. Technol, vol.67, pp.299-317, 1987.

M. A. Drake, T. D. Boylston, K. D. Spence, and B. G. Swanson, Chemical and sensory effects of a Lactobacillus adjunct in Cheddar cheese, Food Research International, vol.29, issue.3-4, pp.381-387, 1996.
DOI : 10.1016/0963-9969(96)00006-3

F. A. Exterkate, Location of Peptidases Outside and Inside the Membrane of Streptococcus cremoris, Appl. Environ. Microbiol, vol.47, pp.177-183, 1984.

F. A. Exterkate and A. C. Alting, The Conversion of the ??-s1-Casein-(1-23)-Fragment by the Free and Bound Form of the Cell-Envelope Proteinase of Lactococcus lactis subsp. cremoris Under Conditions Prevailing in Cheese, Systematic and Applied Microbiology, vol.16, issue.1, pp.1-8, 1993.
DOI : 10.1016/S0723-2020(11)80242-0

F. A. Exterkate, A. C. Alting, and C. J. Slangen, Conversion of ??s1-Casein-(24-199)-Fragment and ??-Casein under Cheese Conditions by Chymosin and Starter Peptidases, Systematic and Applied Microbiology, vol.18, issue.1, 1995.
DOI : 10.1016/S0723-2020(11)80442-X

F. A. Exterkate, C. Slangen, and R. J. Siezen, Effect of genetically modified Lactococcus lactis cell-envelope proteinases with altered specificity on the course of casein degradation under cheese conditions, International Dairy Journal, vol.11, issue.4-7, pp.363-371, 2001.
DOI : 10.1016/S0958-6946(01)00065-6

S. Thierry, F. Lortal, and . Postollec, Reverse transcription quantitative PCR revealed persistency of thermophilic lactic acid bacteria metabolic activity until the end of the ripening of Emmental cheese, Food Microbiol, vol.29, pp.132-140, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01209298

P. F. Fox and B. F. Walley, Influence of sodium chloride on the proteolysis of casein by rennet and by pepsin, Journal of Dairy Research, vol.47, issue.02, pp.165-170, 1971.
DOI : 10.3891/acta.chem.scand.13-1839

M. T. Fröhlich-wyder and H. P. Bachmann, Cheeses with propionic acid fermentation, Cheese: Chemistry, p.141, 2004.

V. Gagnaire, D. Molle, M. Herrouin, and J. Leonil, Peptides Identified during Emmental Cheese Ripening:?? Origin and Proteolytic Systems Involved, Journal of Agricultural and Food Chemistry, vol.49, issue.9, pp.4402-4413, 2001.
DOI : 10.1021/jf000895z

W. Galia, C. Perrin, M. Genay, and A. Dary, Variability and molecular typing of Streptococcus thermophilus strains displaying different proteolytic and acidifying properties, International Dairy Journal, vol.19, issue.2, pp.89-95, 2009.
DOI : 10.1016/j.idairyj.2008.08.004

M. Genay, L. Sadat, V. Gagnaire, and S. Lortal, prtH2, Not prtH, Is the Ubiquitous Cell Wall Proteinase Gene in Lactobacillus helveticus, Applied and Environmental Microbiology, vol.75, issue.10, pp.3238-3249, 2009.
DOI : 10.1128/AEM.02395-08

URL : https://hal.archives-ouvertes.fr/hal-01190820

M. R. Green and J. Sambrook, Molecular cloning: a laboratory manual, 2012.

J. C. Gripon, M. J. Desmazeaud, D. L. Bars, and J. L. Bergere, Etude du r??le des micro-organismes et des enzymes au cours de la maturation des fromages. II. - Influence de la pr??sure commerciale, Le Lait, vol.55, issue.548, pp.502-516, 1975.
DOI : 10.1051/lait:197554828

Z. Hafeez, C. Cakir-kiefer, J. Girardet, J. Jardin, C. Perrin et al., Hydrolysis of milk-derived bioactive peptides by cell-associated extracellular peptidases of Streptococcus thermophilus, Applied Microbiology and Biotechnology, vol.10, issue.22, pp.9787-9799, 2013.
DOI : 10.1016/S0168-1656(97)00157-0

URL : https://hal.archives-ouvertes.fr/hal-01209516

E. Heiss, Studies of rapid methods for the determination of fat content of cheese, Dtsch. Molk.-Ztg, vol.82, pp.67-70, 1961.

Y. Ishihama, Y. Oda, T. Tabata, T. Sato, T. Nagasu et al., Exponentially Modified Protein Abundance Index (emPAI) for Estimation of Absolute Protein Amount in Proteomics by the Number of Sequenced Peptides per Protein, Molecular & Cellular Proteomics, vol.949, issue.9, pp.1265-1272, 2005.
DOI : 10.1016/0167-4781(88)90048-6

H. Korhonen, Milk-derived bioactive peptides: From science to applications, Journal of Functional Foods, vol.1, issue.2, pp.177-187, 2009.
DOI : 10.1016/j.jff.2009.01.007

U. K. Laemmli, Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4, Nature, vol.244, issue.5259, pp.680-685, 1970.
DOI : 10.1101/SQB.1963.028.01.053

C. N. Lane and P. F. Fox, The individual or combined action of chymosin and plasmin on sodium caseinate or ??-casein in solution: effect of NaCl and pH, Le Lait, vol.79, issue.4, pp.423-434, 1999.
DOI : 10.1051/lait:1999435

URL : https://hal.archives-ouvertes.fr/hal-00929662

X. Lecomte, V. Gagnaire, V. Briard-bion, J. Jardin, S. Lortal et al., The naturally competent strain Streptococcus thermophilus LMD-9 as a new tool to anchor heterologous proteins on the cell surface, Microbial Cell Factories, vol.13, issue.1, pp.82-92, 2014.
DOI : 10.1186/1475-2859-13-82

URL : https://hal.archives-ouvertes.fr/hal-01209649

L. Lemieux and R. Simard, Bitter flavour in dairy products. II. A review of bitter peptides from caseins: their formation, isolation and identification, structure masking and inhibition, Le Lait, vol.72, issue.4, pp.335-382, 1992.
DOI : 10.1051/lait:1992426

URL : https://hal.archives-ouvertes.fr/hal-00929271

A. Marcos, M. A. Esteban, F. León, and J. Fernández-salguero, Electrophoretic Patterns of European Cheeses: Comparison and Quantitation, Journal of Dairy Science, vol.62, issue.6, pp.892-900, 1979.
DOI : 10.3168/jds.S0022-0302(79)83345-7

D. M. Mulvihill and P. F. Fox, Proteolysis of Bovine ?-Casein by Chymosin: Influence of pH, Urea and Sodium Chloride, Ir. J. Food Sci. Technol, vol.2, pp.135-139, 1978.

. Surfomics, Shaving live organisms for a fast proteomic identification of surface proteins, J. Proteomics, vol.97, pp.164-176

K. N. Pearce, The complexometric determination of calcium in dairy products, N Z J Dairy Sci Technol, vol.12, p.113, 1977.

J. A. Pederson, G. J. Mileski, B. C. Weimer, and J. L. Steele, Genetic characterization of a cell envelope-associated proteinase from Lactobacillus helveticus CNRZ32, J. Bacteriol, vol.181, pp.4592-4597, 1999.

J. Rappsilber, U. Ryder, A. I. Lamond, and M. Mann, Large-Scale Proteomic Analysis of the Human Spliceosome, Genome Research, vol.12, issue.8, pp.1231-1245, 2002.
DOI : 10.1101/gr.473902

R. Team, R: A language and environment for statistical computing. R Foundation for Statistical Computing, 2014.

R. Richoux, G. Roset, M. H. Famelart, and J. R. Kerjean, Diversit?? de quelques propri??t??s fonctionnelles ?? chaud de l'Emmental fran??ais, Le Lait, vol.81, issue.4, pp.547-559, 2001.
DOI : 10.1051/lait:2001150

URL : http://lait.dairy-journal.org/articles/lait/pdf/2001/04/06-richoux.pdf

L. Sadat-mekmene, M. Genay, D. Atlan, S. Lortal, and V. Gagnaire, Original features of cell-envelope proteinases of Lactobacillus helveticus. A review, International Journal of Food Microbiology, vol.146, issue.1, pp.1-13, 2011.
DOI : 10.1016/j.ijfoodmicro.2011.01.039

L. Sadat-mekmene, J. Jardin, C. Corre, D. Molle, R. Richoux et al., ABSTRACT, Applied and Environmental Microbiology, vol.77, issue.1, pp.179-186, 2011.
DOI : 10.1128/AEM.01466-10

S. Jardin, S. Le-feunteun, V. Lortal, and . Gagnaire, Lactobacillus helveticus as a tool to change proteolysis and functionality in Swiss-type cheeses, J. Dairy Sci, vol.96, pp.1455-1470, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01191386

H. Schägger and G. Jagow, Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa, Analytical Biochemistry, vol.166, issue.2, pp.368-379, 1987.
DOI : 10.1016/0003-2697(87)90587-2

O. Schneewind and D. M. Missiakas, Protein secretion and surface display in Gram-positive bacteria, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.454, issue.7205, pp.1123-1139, 2012.
DOI : 10.1038/nature07219

E. Soeryapranata, J. R. Powers, and G. Unlu, Cloning and characterization of debittering peptidases, PepE, PepO, PepO2, PepO3, and PepN, of Lactobacillus helveticus WSU19, International Dairy Journal, vol.17, issue.9, pp.1096-1106, 2007.
DOI : 10.1016/j.idairyj.2007.02.002

N. Solis, M. R. Larsen, and S. J. , Improved accuracy of cell surface shaving proteomics in Staphylococcus aureus using a false-positive control, PROTEOMICS, vol.284, issue.10, pp.2037-2049, 2010.
DOI : 10.1099/00221287-145-9-2497

M. J. Sousa, Y. Ardö, and P. L. Mcsweeney, Advances in the study of proteolysis during cheese ripening, International Dairy Journal, vol.11, issue.4-7, pp.327-345, 2001.
DOI : 10.1016/S0958-6946(01)00062-0

B. E. Terzaghi and W. E. Sandine, Improved medium for lactic Streptococci and their bacteriophages, Appl. Microbiol, vol.29, pp.807-813, 1975.

A. Thierry, D. Salvat-brunaud, M. N. Madec, F. Michel, and J. L. Maubois, Affinage de l'emmental : dynamique des populations bact??riennes et ??volution de la composition de la phase aqueuse, Le Lait, vol.78, issue.5, pp.521-542, 1998.
DOI : 10.1051/lait:1998549

T. A. Tompkins, G. Barreau, and J. R. Broadbent, Complete Genome Sequence of Lactobacillus helveticus R0052, a Commercial Probiotic Strain, Journal of Bacteriology, vol.194, issue.22, pp.6349-6349, 2012.
DOI : 10.1128/JB.01638-12

F. Valence, S. M. Deutsch, R. Richoux, V. Gagnaire, and S. Lortal, Autolysis and related proteolysis in Swiss cheese for two Lactobacillus helveticus strains, Journal of Dairy Research, vol.67, issue.2, pp.261-271, 2000.
DOI : 10.1017/S0022029900004118

K. Masuda and T. Et-kawata, Distribution and chemical characterization of regular arrays in the cell walls of strains of the genus Lactobacillus, FEMS Microbiology Letters, vol.147, issue.2, pp.145-150, 1983.
DOI : 10.1111/j.1348-0421.1982.tb00172.x

C. Matar, J. C. Valdez, M. Medina, M. Rachid, and G. Et-perdigon, Immunomodulating effects of milks fermented by Lactobacillus helveticus and its non-proteolytic variant, Journal of Dairy Research, vol.68, issue.04, pp.601-609, 2001.
DOI : 10.1017/S0022029901005143

L. Miclo, E. Roux, M. Genay, E. Brusseaux, C. Poirson et al., -Caseins by 10 Strains of Streptococcus thermophilus and Resulting Bioactive Peptides, Journal of Agricultural and Food Chemistry, vol.60, issue.2, pp.554-565, 2012.
DOI : 10.1021/jf202176d

H. Miyakawa, S. Kobayashi, S. Shimamura, and M. Et-tomita, Purification and Characterization of an Aminopeptidase from Lactobacillus helveticus LHE-511, Journal of Dairy Science, vol.75, issue.1, pp.27-35, 1992.
DOI : 10.3168/jds.S0022-0302(92)77734-0

J. P. Muller, J. Ozegowski, S. Vettermann, J. Swaving, K. H. Van-wely et al., Interaction of Bacillus subtilis CsaA with SecA and precursor proteins, Biochemical Journal, vol.348, issue.2, pp.367-373, 2000.
DOI : 10.1042/bj3480367

D. M. Mulvihill and P. F. Fox, Proteolysis of Bovine ?-Casein by Chymosin: Influence of pH, Urea and Sodium Chloride, Irish Journal of Food Science and Technology, vol.2, issue.2, pp.135-139, 1978.

W. W. Navarre and O. Et-schneewind, Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope, Microbiology and molecular biology reviews, pp.174-229, 1999.

F. C. Neuhaus and J. Et-baddiley, A Continuum of Anionic Charge: Structures and Functions of D-Alanyl-Teichoic Acids in Gram-Positive Bacteria, Microbiology and Molecular Biology Reviews, vol.67, issue.4, pp.686-723, 2003.
DOI : 10.1128/MMBR.67.4.686-723.2003

A. V. Nickitenko, S. Trakhanov, and F. A. Et-quiocho, 2 angstrom resolution structure of DppA, a periplasmic dipeptide transport chemosensory receptor, Biochemistry, pp.34-51, 1995.

C. J. Oberg, J. R. Broadbent, M. Strickland, and D. J. Et-mcmahon, Diversity in specificity of the extracellular proteinases in Lactobacillus helveticus and Lactobacillus delbrueckii subsp. bulgaricus, Letters in Applied Microbiology, vol.62, issue.6, pp.455-460, 2002.
DOI : 10.1006/plas.1996.0017

N. F. Olson, S. Gunasekaran, and D. D. Et-bogenrief, Chemical and physical properties of cheese and their interactions, Netherlands Milk and Dairy Journal, vol.50, issue.2, pp.279-294, 1996.

H. Ono, N. Yamamoto, M. Maeno, T. Takano, and H. Et-momose, Purification and characterization of a cell-wall associated proteinase of Lactobacillus helveticus CP53, Milchwissenschaft-Milk Science International, vol.52, issue.7, pp.373-377, 1997.

I. Pastar, I. Tonic, N. Golic, M. Kojic, R. Van-kranenburg et al., Identification and Genetic Characterization of a Novel Proteinase, PrtR, from the Human Isolate Lactobacillus rhamnosus BGT10, Applied and Environmental Microbiology, vol.69, issue.10, pp.10-5802, 2003.
DOI : 10.1128/AEM.69.10.5802-5811.2003

J. A. Pederson, G. J. Mileski, B. C. Weimer, and J. L. Et-steele, Genetic characterization of a cell envelope-associated proteinase from Lactobacillus helveticus CNRZ32, Journal of Bacteriology, vol.181, pp.15-4592, 1999.

T. N. Petersen, S. Brunak, V. Heijne, G. Et-nielsen, and H. , SignalP 4.0: discriminating signal peptides from transmembrane regions, Nature Methods, vol.6, issue.10, pp.10-785, 2011.
DOI : 10.1016/0005-2795(75)90109-9

C. M. Petit, J. R. Brown, K. Ingraham, A. P. Bryant, and D. J. Holmes, Lipid modification of prelipoproteins is dispensable for growth in vitro but essential for virulence in Streptococcus pneumoniae, FEMS Microbiology Letters, issue.2, pp.229-233, 0200.

A. Picon and K. H. Et-van-wely, Peptide Binding to the Bacillus subtilis Oligopeptide- Binding Proteins OppA and AppA, Molecular Biology Today, issue.2, pp.21-25, 2001.

A. Podbielski and B. A. Leonard, The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease, Molecular Microbiology, vol.175, issue.6, pp.6-1323, 1998.
DOI : 10.1128/jb.175.5.1452-1456.1993

G. Pritchard and T. Et-coolbear, The physiology and biochemistry of the proteolytic system in lactic acid bacteria, FEMS Microbiology Reviews, vol.73, issue.1-3, pp.1-3179, 1993.
DOI : 10.1016/S0723-2020(89)80046-3

T. B. Rasmussen, M. Danielsen, O. Valina, C. Garrigues, E. Johansen et al., Streptococcus thermophilus Core Genome: Comparative Genome Hybridization Study of 47 Strains, Applied and Environmental Microbiology, vol.74, issue.15, pp.154703-4710, 2008.
DOI : 10.1128/AEM.00132-08

J. R. Reid, K. H. Ng, C. H. Moore, T. Coolbear, and G. G. Et-pritchard, Comparison of bovine beta-casein hydrolysis by PI and PIII-type proteinases from Lactococcus lactis subsp. cremoris, Applied Microbiology and Biotechnology, vol.36, issue.3, pp.344-351, 1991.

L. Sadat-mekmene, R. Richoux, L. Aubert-frogerais, M. Madec, C. Corre et al., Lactobacillus helveticus as a tool to change proteolysis and functionality in Swiss-type cheeses, Journal of Dairy Science, vol.96, issue.3, pp.1455-1470, 2013.
DOI : 10.3168/jds.2012-6179

L. Sadat-mekmene, M. Genay, D. Atlan, S. Lortal, and V. Et-gagnaire, Original features of cell-envelope proteinases of Lactobacillus helveticus. A review, International Journal of Food Microbiology, vol.146, issue.1, pp.1-13, 2011.
DOI : 10.1016/j.ijfoodmicro.2011.01.039

L. Sadat-mekmene, J. Jardin, C. Corre, D. Molle, R. Richoux et al., ABSTRACT, Applied and Environmental Microbiology, vol.77, issue.1, pp.179-186, 2011.
DOI : 10.1128/AEM.01466-10

E. Soeryapranata, J. R. Powers, and G. Et-unlu, Cloning and characterization of debittering peptidases, PepE, PepO, PepO2, PepO3, and PepN, of Lactobacillus helveticus WSU19, International Dairy Journal, vol.17, issue.9, pp.1096-1106, 2007.
DOI : 10.1016/j.idairyj.2007.02.002

Z. Sun, X. Chen, J. Wang, W. Zhao, Y. Shao et al., Complete Genome Sequence of Streptococcus thermophilus Strain ND03, Journal of Bacteriology, vol.193, issue.3, pp.793-794, 2011.
DOI : 10.1128/JB.01374-10

D. L. Taylor, P. N. Ward, C. D. Rapier, J. A. Leigh, and L. D. Bowler, Identification of a Differentially Expressed Oligopeptide Binding Protein (OppA2) in Streptococcus uberis by Representational Difference Analysis of cDNA, Journal of Bacteriology, vol.185, issue.17, pp.17-5210, 2003.
DOI : 10.1128/JB.185.17.5210-5219.2003

P. Vandamme, B. Pot, M. Gillis, D. Vos, P. Kersters et al., Polyphasic taxonomy, a consensus approach to bacterial systematics, Microbiological reviews, et Swings J, vol.60, issue.2, pp.407-438, 1996.

A. Verheul, F. M. Rombouts, and T. Et-abee, Utilization of oligopeptides by Listeria monocytogenes Scott A, Applied and Environmental Microbiology, vol.64, issue.3, pp.1059-1065, 1998.

M. M. Vickerman, S. Iobst, A. A. Jesionowski, and S. R. Gill, Genome-Wide Transcriptional Changes in Streptococcus gordonii in Response to Competence Signaling Peptide, Journal of Bacteriology, vol.189, issue.21, pp.7799-7807, 2007.
DOI : 10.1128/JB.01023-07

S. Visser, Proteolytic Enzymes and Their Relation to Cheese Ripening and Flavor: An Overview, Journal of Dairy Science, vol.76, issue.1, pp.329-350, 1993.
DOI : 10.3168/jds.S0022-0302(93)77354-3

S. Visser, F. A. Exterkate, C. J. Slangen, . Et-de, and G. J. Veer, Comparative study of action of cell wall proteinases from various strains of Streptococcus cremoris on bovine alpha(s1)-, beta-, and kappa-casein, Applied and environmental microbiology, vol.52, issue.5, pp.1162-1166, 1986.

S. Visser, A. J. Robben, and C. J. Et-slangen, Specificity of a cell-envelope-located proteinase (PIII-type) from Lactococcus lactis subsp. cremoris AM1 in its action on bovine ?-casein, Applied Microbiology and Biotechnology, vol.35, issue.4, pp.477-483, 1991.
DOI : 10.1007/BF00169753

P. Vos, I. Boerrigter, G. Buist, A. Haandrikman, M. Nijhuis et al., serine proteinase by construction of hybrid enzymes, "Protein Engineering, Design and Selection", vol.4, issue.4, pp.479-484, 1991.
DOI : 10.1093/protein/4.4.479

P. Vos, G. Simons, R. J. Siezen, and W. M. Et-de-vos, Primary structure and organization of the gene for a procaryotic, cell envelope-located serine proteinase, The Journal of biological chemistry, vol.264, pp.23-13579, 1989.

A. Wasko, M. Polak-berecka, A. Kuzdralinski, and T. Et-skrzypek, Variability of Slayer proteins in Lactobacillus helveticus strains, Anaerobe, pp.25-53, 2014.

S. Woodcock, J. P. Mornon, and B. Et-henrissat, Detection of secondary structure elements in proteins by hydrophobic cluster analysis, "Protein Engineering, Design and Selection", vol.5, issue.7, pp.629-635, 1992.
DOI : 10.1093/protein/5.7.629

N. Yamamoto, A. Akino, and T. Et-takano, Antihypertensive Effect of the Peptides Derived from Casein by an Extracellular Proteinase from Lactobacillus helveticus CP790, Journal of Dairy Science, vol.77, issue.4, pp.917-922, 1994.
DOI : 10.3168/jds.S0022-0302(94)77026-0

N. Yamamoto, A. Akino, and T. Et-takano, Purification and Specificity of a Cell-Wall-Associated Proteinase from Lactobacillus helveticus CP790, The Journal of Biochemistry, vol.114, issue.5, pp.740-745, 1993.
DOI : 10.1093/oxfordjournals.jbchem.a124247

W. Yu and F. Et-gotz, Cell Wall Antibiotics Provoke Accumulation of Anchored mCherry in the Cross Wall of Staphylococcus aureus, PLoS ONE, vol.50, issue.1, pp.384-392, 2012.
DOI : 10.1371/journal.pone.0030076.s003

M. M. Zhou, D. Theunissen, M. Wels, and R. J. Et-siezen, LAB-Secretome: a genome-scale comparative analysis of the predicted extracellular and surface-associated proteins of Lactic Acid Bacteria, BMC Genomics, vol.11, issue.1, p.000285385400002, 2010.
DOI : 10.1186/1471-2164-11-651

A. Annexe, R. Bellanger, X. Roberts, A. P. Morel, C. Choulet et al., Conjugative Transfer of the Integrative Conjugative Elements ICESt1 and ICESt3 from Streptococcus thermophilus, J. Bacteriol, vol.191, pp.2764-2775, 2009.

A. Berlec, M. Ravnikar, and B. Strukelj, Lactic acid bacteria as oral delivery systems for biomolecules, Pharmazie, vol.67, pp.891-898, 2012.

L. G. Bermúdez-humarán, P. Kharrat, J. M. Chatel, and P. Langella, Lactococci and lactobacilli as mucosal delivery vectors for therapeutic proteins and DNA vaccines. Microbial. Cell Fact, p.4, 2011.

L. G. Bermúdez-humarán, C. Aubry, J. P. Motta, C. Deraison, L. Steidler et al., Engineering lactococci and lactobacilli for human health, Current Opinion in Microbiology, vol.16, issue.3, pp.278-283, 2013.
DOI : 10.1016/j.mib.2013.06.002

T. Blomqvist, H. Steinmoen, and L. S. Havarstein, Natural Genetic Transformation: a Novel Tool for Efficient Genetic Engineering of the Dairy Bacterium Streptococcus thermophilus, Applied and Environmental Microbiology, vol.72, issue.10, pp.6751-6756, 2006.
DOI : 10.1128/AEM.01156-06

T. Blomqvist, H. Steinmoen, and L. S. Havarstein, Pheromone-induced expression of recombinant proteins in Streptococcus thermophilus, Archives of Microbiology, vol.33, issue.6, pp.465-473, 2006.
DOI : 10.1006/rwfm.1999.0731

F. Carlsson, M. Stalhammar-carlemalm, K. Flardh, C. Sandin, E. Carlemalm et al., Signal sequence directs localized secretion of bacterial surface proteins, Nature, vol.50, issue.7105, pp.943-946, 2006.
DOI : 10.1046/j.1365-2958.2003.03674.x

O. K. Chang, C. Perrin, W. Galia, F. Saulnier, L. Miclo et al., Release of the cell-envelope protease PrtS in the growth medium of Streptococcus thermophilus 4F44, International Dairy Journal, vol.23, issue.2, pp.91-98, 2012.
DOI : 10.1016/j.idairyj.2011.10.014

S. Chang and T. Yan, Genetic engineering techniques for lactic acid bacteria: construction of a stable shuttle vector and expression vector for ??-glucuronidase, Biotechnology Letters, vol.12, issue.2, 2014.
DOI : 10.1023/A:1008820013022

H. Chouayekh, P. Serror, S. Boudebbouze, and E. Maguin, gene, FEMS Microbiology Letters, vol.293, issue.2, pp.232-239, 2009.
DOI : 10.1111/j.1574-6968.2009.01522.x

URL : https://hal.archives-ouvertes.fr/hal-01443853

P. E. Coderre and G. A. Somkuti, Cloning and Expression of the Pediocin Operon in Streptococcus thermophilus and Other Lactic Fermentation Bacteria, Current Microbiology, vol.39, issue.5, pp.295-301, 1999.
DOI : 10.1007/s002849900462

N. G. Cortes-perez, S. Ah-leung, L. G. Bermúdez-humarán, G. Corthier, P. Langella et al., Allergy Therapy by Intranasal Administration with Recombinant <i>Lactococcus lactis</i> Producing Bovine &beta;-Lactoglobulin, International Archives of Allergy and Immunology, vol.150, issue.1, 2009.
DOI : 10.1159/000210377

D. Carmen, S. , D. Moreno-de-leblanc, A. Martin, R. Chain et al., ABSTRACT, Applied and Environmental Microbiology, vol.80, issue.3, pp.869-877, 2014.
DOI : 10.1128/AEM.03296-13

D. Dandoy, C. Fremaux, M. H. De-frahan, P. Horvath, P. Boyaval et al., The fast milk acidifying phenotype of Streptococcus thermophilus can be acquired by natural transformation of the genomic island encoding the cell-envelope proteinase PrtS, Microbial Cell Factories, vol.10, issue.Suppl 1, p.21, 2011.
DOI : 10.1128/JB.01374-10

E. Demerdash, H. A. Heller, K. J. Geis, and A. , Application of the shsp Gene, Encoding a Small Heat Shock Protein, as a Food-Grade Selection Marker for Lactic Acid Bacteria, Applied and Environmental Microbiology, vol.69, issue.8, 2003.
DOI : 10.1128/AEM.69.8.4408-4412.2003

M. Elli, M. L. Callegari, S. Ferrari, E. Bessi, D. Cattivelli et al., Survival of Yogurt Bacteria in the Human Gut, Applied and Environmental Microbiology, vol.72, issue.7, 2006.
DOI : 10.1128/AEM.02950-05

URL : https://hal.archives-ouvertes.fr/hal-00294424

B. Foligné, C. Daniek, and B. Pot, Probiotics from research to market: the possibilities, risks and challenges, Current Opinion in Microbiology, vol.16, issue.3, pp.284-292, 2013.
DOI : 10.1016/j.mib.2013.06.008

L. Fontaine, C. Boutry, M. H. De-frahan, B. Delplace, C. Fremaux et al., A Novel Pheromone Quorum-Sensing System Controls the Development of Natural Competence in Streptococcus thermophilus and Streptococcus salivarius, Journal of Bacteriology, vol.192, issue.5, pp.1444-1454, 2010.
DOI : 10.1128/JB.01251-09

L. Fontaine, D. Dandoy, C. Boutry, B. Delplace, M. H. De-frahan et al., Development of a Versatile Procedure Based on Natural Transformation for Marker-Free Targeted Genetic Modification in Streptococcus thermophilus, Applied and Environmental Microbiology, vol.76, issue.23, pp.7870-7877, 2010.
DOI : 10.1128/AEM.01671-10

L. Fontaine, P. Goffin, H. Dubout, B. Delplace, A. Baulard et al., Mechanism of competence activation by the ComRS signalling system in streptococci, Molecular Microbiology, vol.5, issue.6, pp.1113-1132, 2013.
DOI : 10.1038/nrg1315

URL : https://hal.archives-ouvertes.fr/hal-01003320

R. Gardan, C. Besset, A. Guillot, C. Gitton, and V. Monnet, The Oligopeptide Transport System Is Essential for the Development of Natural Competence in Streptococcus thermophilus Strain LMD-9, Journal of Bacteriology, vol.191, issue.14, pp.4647-4655, 2009.
DOI : 10.1128/JB.00257-09

R. Gardan, C. Besset, C. Gitton, A. Guillot, L. Fontaine et al., Extracellular Life Cycle of ComS, the Competence-Stimulating Peptide of Streptococcus thermophilus, Journal of Bacteriology, vol.195, issue.8, pp.1845-1855, 2013.
DOI : 10.1128/JB.02196-12

URL : https://hal.archives-ouvertes.fr/hal-01001084

A. Geis, H. A. Demerdash, and K. J. Heller, Sequence analysis and characterization of plasmids from Streptococcus thermophilus, Plasmid, vol.50, issue.1, pp.53-69, 2003.
DOI : 10.1016/S0147-619X(03)00029-5

Y. J. Goh, C. Goin, S. O-'flaherty, E. Altermann, and R. Hutkins, Specialized adaptation of a lactic acid bacterium to the milk environment: the comparative genomics of Streptococcus thermophilus LMD-9, Microbial Cell Factories, vol.10, issue.Suppl 1, p.22, 2011.
DOI : 10.1128/AEM.01984-08

H. Gonzalez-marquez, C. Perrin, P. Bracquart, C. Guimont, and G. Linden, A 16 kDa protein family overexpressed by Streptococcus thermophilus PB18 in acid environments, Microbiology, vol.143, issue.5, pp.1587-1594, 1997.
DOI : 10.1099/00221287-143-5-1587

M. R. Green and J. Sambrook, Molecular cloning: a laboratory manual, 2012.

F. Guarner, G. Perdigon, G. Corthier, S. Salminen, B. Koletzko et al., Should yoghurt cultures be considered probiotic?, British Journal of Nutrition, vol.49, issue.06, pp.783-786, 2005.
DOI : 10.1016/S0168-1605(97)00136-0

E. Haque, R. Chand, and S. Kapila, Biofunctional Properties of Bioactive Peptides of Milk Origin, Food Reviews International, vol.345, issue.1, pp.28-43, 2009.
DOI : 10.1159/000016618

S. Hazebrouck, L. Pothelune, V. Azevedo, G. Corthier, J. M. Wal et al., Efficient production and secretion of bovine beta-lactoglobulin by Lactobacillus casei, 2007.

P. Hols, F. Hancy, L. Fontaine, B. Grossiord, D. Prozzi et al., New insights in the molecular biology and physiology of Streptococcus thermophilus revealed by comparative genomics, 2005.

M. Junjua, W. Galia, N. Gaci, O. Uriot, M. Genay et al., and validation using the lactose operon promoter, Journal of Applied Microbiology, vol.15, issue.3, pp.620-631, 2014.
DOI : 10.1016/j.copbio.2004.02.006

URL : https://hal.archives-ouvertes.fr/hal-01562062

P. Kanmani, R. S. Kumar, N. Yuvaraj, K. A. Paari, V. Pattukumar et al., Probiotics and Its Functionally Valuable Products???A Review, Critical Reviews in Food Science and Nutrition, vol.35, issue.2, pp.641-658, 2013.
DOI : 10.1016/0168-1605(94)90121-X

J. K. Kondo and L. L. Mckay, Plasmid transformation of Streptococcus lactis protoplasts: optimization and use in molecular cloning, Appl. Environ. Microbiol, vol.48, pp.252-259, 1984.

S. Labrie, C. Bart, C. Vadeboncoeur, and S. Moineau, Use of an ??-Galactosidase Gene as a Food-Grade Selection Marker for Streptococcus thermophilus, Journal of Dairy Science, vol.88, issue.7, pp.2341-2347, 2005.
DOI : 10.3168/jds.S0022-0302(05)72912-X

X. Lecomte, V. Gagnaire, V. Briard-brion, J. Jardin, S. Lortal et al., The naturally competent strain Streptococcus thermophilus LMD-9 as a new tool to anchor heterologous proteins on the cell surface, Microbial Cell Factories, vol.13, issue.1, p.82, 2014.
DOI : 10.1186/1475-2859-13-82

URL : https://hal.archives-ouvertes.fr/hal-01209649

F. Levander, M. Svensson, and P. Rådström, Enhanced Exopolysaccharide Production by Metabolic Engineering of Streptococcus thermophilus, Applied and Environmental Microbiology, vol.68, issue.2, pp.784-790, 2002.
DOI : 10.1128/AEM.68.2.784-790.2002

F. L. Macrina, K. R. Jones, and P. H. Wood, Chimeric streptococcal plasmids and their use as molecular cloning vehicles in Streptococcus sanguis (Challis), J. Bacteriol, vol.143, pp.1425-1435, 1980.

E. Maguin, P. Duwat, T. Hege, S. D. Ehrlich, and A. Gruss, New thermosensitive plasmid for gram-positive bacteria., Journal of Bacteriology, vol.174, issue.17, pp.5633-5638, 1992.
DOI : 10.1128/jb.174.17.5633-5638.1992

E. Maguin, H. Prevost, S. D. Ehrlich, and A. Gruss, Efficient insertional mutagenesis in lactococci and other gram-positive bacteria., Journal of Bacteriology, vol.178, issue.3, pp.931-935, 1996.
DOI : 10.1128/jb.178.3.931-935.1996

G. Marcial, J. Messing, B. Menchicchi, F. M. Goycoolea, G. Faller et al., Effects of polysaccharide isolated from Streptococcus thermophilus CRL1190 on human gastric epithelial cells, International Journal of Biological Macromolecules, vol.62, pp.217-224, 2013.
DOI : 10.1016/j.ijbiomac.2013.08.011

L. A. Marraffini, A. C. Dedent, and O. Schneewind, Sortases and the Art of Anchoring Proteins to the Envelopes of Gram-Positive Bacteria, Microbiology and Molecular Biology Reviews, vol.70, issue.1, pp.192-221, 2006.
DOI : 10.1128/MMBR.70.1.192-221.2006

D. D. Mater, L. Bretigny, O. Firmesse, M. J. Flores, A. Mogenet et al., survive gastrointestinal transit of healthy volunteers consuming yogurt, FEMS Microbiology Letters, vol.68, issue.2, pp.185-187, 2005.
DOI : 10.1016/j.femsle.2005.07.006

L. Miclo, E. Roux, M. Genay, E. Brusseaux, C. Poirson et al., -Caseins by 10 Strains of Streptococcus thermophilus and Resulting Bioactive Peptides, Journal of Agricultural and Food Chemistry, vol.60, issue.2, pp.554-565, 2012.
DOI : 10.1021/jf202176d

N. P. Moller, K. E. Scholz-ahrens, N. Roos, and J. Schrezenmeir, Bioactive peptides and proteins from foods: indication for health effects, European Journal of Nutrition, vol.372, issue.suppl 1, pp.171-182, 2008.
DOI : 10.1002/biof.5520120122

D. Mora, C. Monnet, C. Parini, S. Guglielmetti, A. Mariani et al., Urease biogenesis in Streptococcus thermophilus, Research in Microbiology, vol.156, issue.9, pp.897-903, 2005.
DOI : 10.1016/j.resmic.2005.04.005

K. Ohsawa, H. Satsu, K. Ohki, M. Enjoh, T. Takano et al., Model of Mammalian Gastrointestinal Digestion, Journal of Agricultural and Food Chemistry, vol.56, issue.3, pp.854-858, 2008.
DOI : 10.1021/jf072671n

O. Sullivan, T. F. Fitzgerald, and G. F. , Electrotransformation of industrial strains of Streptococcus thermophilus, Journal of Applied Microbiology, vol.165, issue.2, pp.275-283, 1999.
DOI : 10.1128/jb.165.3.831-836.1986

P. M. Petrova and D. E. Gouliamova, Rapid Screening of Plasmid-Encoded Small hsp-Genes in Streptococcus thermophilus, Current Microbiology, vol.43, issue.5, pp.422-427, 2006.
DOI : 10.1007/s00284-006-0175-6

J. J. Qin, R. Q. Li, J. Raes, M. Arumugam, K. S. Burgdorf et al., A human gut microbial gene catalogue established by metagenomic sequencing, Nature, vol.13, issue.7285, pp.59-70, 2010.
DOI : 10.1101/gr.229202. Article published online before March 2002

URL : https://hal.archives-ouvertes.fr/cea-00908974

J. A. Renye and G. A. Somkuti, Cloning of milk-derived bioactive peptides in Streptococcus thermophilus, Biotechnology Letters, vol.98, issue.4, pp.723-730, 2008.
DOI : 10.1111/j.1574-6968.1999.tb08759.x

J. A. Renye and G. A. Somkuti, Insertion of a heterologous gene construct into a non-functional ORF of the Streptococcus thermophilus chromosome, Biotechnology Letters, vol.118, issue.5, pp.759-764, 2009.
DOI : 10.1111/j.1574-6968.1999.tb08759.x

J. A. Renye and G. A. Somkuti, Nisin-induced expression of pediocin in dairy lactic acid bacteria, Journal of Applied Microbiology, vol.72, pp.2142-2151, 2010.
DOI : 10.1016/j.bbapap.2007.12.002

J. A. Renye, G. A. Somkuti, J. I. Garabal, and L. Du, Heterologous production of pediocin for the control of Listeria monocytogenes in dairy foods, Food Control, vol.22, issue.12, pp.1887-1892, 2011.
DOI : 10.1016/j.foodcont.2011.04.031

M. Rhimi, H. Chouayekh, I. Gouillouard, E. Maguin, and S. Bejar, Production of d-tagatose, a low caloric sweetener during milk fermentation using l-arabinose isomerase, Bioresource Technology, vol.102, issue.3, pp.3309-3315, 2011.
DOI : 10.1016/j.biortech.2010.10.078

URL : https://hal.archives-ouvertes.fr/hal-01001451

G. Robitaille, S. Moineau, D. St-gelais, C. Vadeboncoeur, and M. Britten, Galactose Metabolism and Capsule Formation in a Recombinant Strain of Streptococcus thermophilus with a Galactose-Fermenting Phenotype, Journal of Dairy Science, vol.90, issue.9, pp.4051-4057, 2007.
DOI : 10.3168/jds.2007-0140

G. Robitaille, A. Tremblay, S. Moineau, D. St-gelais, C. Vadeboncoeur et al., Fat-free yogurt made using a galactose-positive exopolysaccharide-producing recombinant strain of Streptococcus thermophilus, Journal of Dairy Science, vol.92, issue.2, pp.477-482, 2009.
DOI : 10.3168/jds.2008-1312

N. Rodriguez, J. M. Salgado, S. Cortes, and J. M. Dominguez, Alternatives for biosurfactants and bacteriocins extraction from Lactococcus lactis cultures produced under different pH conditions, Letters in Applied Microbiology, vol.51, pp.226-233, 2010.
DOI : 10.1111/j.1472-765X.2010.02882.x

F. Rossi, M. Marzotto, S. Cremonese, M. Rizzotti, and S. Torriani, Diversity of Streptococcus thermophilus in bacteriocin production; inhibitory spectrum and occurrence of thermophilin genes, Food Microbiology, vol.35, issue.1, pp.27-33, 2013.
DOI : 10.1016/j.fm.2013.02.006

L. Sadat-mekmene, M. Genay, D. Atlan, S. Lortal, and S. Gagnaire, Original features of cell-envelope proteinases of Lactobacillus helveticus. A review, International Journal of Food Microbiology, vol.146, issue.1, pp.1-13, 2011.
DOI : 10.1016/j.ijfoodmicro.2011.01.039

I. Sastalla, K. Chim, Y. C. Cheung, A. P. Pomerantsev, and S. H. Leppla, Codon-Optimized Fluorescent Proteins Designed for Expression in Low-GC Gram-Positive Bacteria, Applied and Environmental Microbiology, vol.75, issue.7, pp.2099-2110, 2009.
DOI : 10.1128/AEM.02066-08

J. Shareck, Y. Choi, B. Lee, and C. B. Miguez, Cloning Vectors Based on Cryptic Plasmids Isolated from Lactic Acid Bacteria:Their Characteristics and Potential Applications in Biotechnology, Critical Reviews in Biotechnology, vol.35, issue.4, pp.155-208, 2004.
DOI : 10.1006/plas.1996.0034

O. Schneewind and D. M. Missiakas, Protein secretion and surface display in Gram-positive bacteria, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.454, issue.7205, pp.1123-1139, 2012.
DOI : 10.1038/nature07219

P. Slos, J. C. Bourquin, Y. Lemoine, and A. Mercenier, Isolation and characterization of chormosomal promoters of Streptococcus salivarius subsp. thermophilus, 1991.

D. K. Solaiman and G. A. Somkuti, Shuttle Vectors Developed from Streptococcus thermophilus Native Plasmid, Plasmid, vol.30, issue.1, pp.67-78, 1993.
DOI : 10.1006/plas.1993.1034

D. K. Solaiman and G. A. Somkuti, Expression ofStreptomyces melC andchoA genes by a clonedStreptococcus thermophilus promoter STP2201, Journal of Industrial Microbiology, vol.53, issue.1, pp.39-44, 1995.
DOI : 10.1007/BF01570011

D. K. Solaiman and G. A. Somkuti, Construction of a green-fluorescent protein-based, insertion-inactivation shuttle vector for lactic acid bacteria and Escherichia coli, Biotechnology Letters, vol.19, issue.12, pp.1175-1179, 1997.
DOI : 10.1023/A:1018473501442

D. K. Solaiman and G. A. Somkuti, Characterization of pER371-based Streptococcus thermophilus-Escherichia coli shuttle vectors, Biotechnology Letters, vol.19, issue.7, pp.595-598, 1997.
DOI : 10.1023/A:1018362025665

G. A. Somkuti and D. H. Steinberg, Distribution and analysis of plasmids inStreptococcus thermophilus, Journal of Industrial Microbiology, vol.38, issue.3, pp.157-163, 1986.
DOI : 10.1016/0005-2787(75)90132-X

G. A. Somkuti and D. H. Steinberg, Genetic transformation of Streptococcus thermophilus by electroporation, Biochimie, vol.70, issue.4, pp.579-585, 1988.
DOI : 10.1016/0300-9084(88)90095-8

G. A. Somkuti, D. K. Solaiman, T. L. Johnson, and D. H. Steinberg, Transfer and expression of a Streptomyces cholesterol oxidase gene in Streptococcus thermophilus, Biotechnol. Appl. Biochem, vol.13, pp.238-245, 1991.

G. A. Somkuti, D. K. Solaiman, and D. H. Steinberg, Cloning of a tyrosinase gene in Streptococcus thermophilus, Biotechnology Letters, vol.15, issue.8, pp.773-778, 1993.
DOI : 10.1007/BF00180140

G. A. Somkuti and D. H. Steinberg, Pediocin production by recombinant lactic acid bacteria, Biotechnology Letters, vol.25, issue.6, pp.473-477, 2003.
DOI : 10.1023/A:1022652028835

M. Svensson, E. Waak, U. Svensson, and P. Rådström, Metabolically Improved Exopolysaccharide Production by Streptococcus thermophilus and Its Influence on the Rheological Properties of Fermented Milk, Applied and Environmental Microbiology, vol.71, issue.10, pp.6398-6400, 2005.
DOI : 10.1128/AEM.71.10.6398-6400.2005

N. Turgeon and S. Moineau, Isolation and Characterization of a Streptococcus thermophilus Plasmid Closely Related to the pMV158 Family, Plasmid, vol.45, issue.3, pp.171-183, 2001.
DOI : 10.1006/plas.2001.1517

K. Vaillancourt, J. Lemay, M. Lamoureux, M. Frenette, S. Moineau et al., Characterization of a Galactokinase-Positive Recombinant Strain of Streptococcus thermophilus, Applied and Environmental Microbiology, vol.70, issue.8, pp.4596-4603, 2004.
DOI : 10.1128/AEM.70.8.4596-4603.2004

K. Vaillancourt, N. Bedard, C. Bart, M. Tessier, G. Robitaille et al., Role of galK and galM in Galactose Metabolism by Streptococcus thermophilus, Applied and Environmental Microbiology, vol.74, issue.4, pp.1264-1267, 2008.
DOI : 10.1128/AEM.01585-07

W. Y. Wong, P. Su, G. E. Allison, C. Liu, and N. W. Dunn, A Potential Food-Grade Cloning Vector for Streptococcus thermophilus That Uses Cadmium Resistance as the Selectable Marker, Applied and Environmental Microbiology, vol.69, issue.10, pp.5767-5771, 2003.
DOI : 10.1128/AEM.69.10.5767-5771.2003

V. Valorisation-des-résultats-publications-xavier-lecomte, V. Gagnaire, J. Briard-bion, S. Jardin, A. Lortal et al., The naturally competent strain Streptococcus thermophilus LMD-9 as a new tool to anchor heterologous proteins on the cell surface Microbial Cell Factories, 2014.

L. Xavier, G. Valérie, L. Sylvie, D. Annie, and G. Magali, Streptococcus thermophilus, an emerging and promising tool for heterologous expression: advantages and future trends Food Microbiology, p.34, 2014.

G. Valérie, L. Xavier, R. Romain, K. Jean-rené, and A. Thierry, Proteinases of Lactobacillus helveticus and their distinct capability to hydrolyze ?s1 and -?-caseins at different NaCl concentrations 1st International PLEASURE conference, 2014.

G. Valérie, L. Xavier, P. Nicolas, R. Romain, A. Lydie et al., Proteinases of Lactobacillus helveticus and their distinct capability to hydrolyze alpha-s1 and beta-caseins at different NaCl concentrations: from in vitro experiments to Swiss-type cheeses, 17 Word Congress of Food Science & Technology, 2014.