Recruitment of TIF1?? to Chromatin via Its PHD Finger-Bromodomain Activates Its Ubiquitin Ligase and Transcriptional Repressor Activities, Molecular Cell, vol.43, issue.1, pp.85-96, 2011. ,
DOI : 10.1016/j.molcel.2011.05.020
Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-?? Pathways, Cell, vol.139, issue.4, pp.757-769, 2009. ,
DOI : 10.1016/j.cell.2009.09.035
Gene analysis techniques and susceptibility gene discovery in??non-BRCA1/BRCA2 familial breast cancer, Surgical Oncology, vol.24, issue.2, pp.100-109, 2015. ,
DOI : 10.1016/j.suronc.2015.04.003
[Effect of weekly paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide as neoadjuvant treatment for patients with triple-negative and luminal-type breast cancer -a multicenter study], Gan To Kagaku Ryoho, vol.42, pp.45-50, 2015. ,
A Smad action turnover switch operated by WW domain readers of a phosphoserine code, Genes & Development, vol.25, issue.12, pp.1275-1288, 2011. ,
DOI : 10.1101/gad.2060811
Premalignant and In Situ Breast Disease: Biology and Clinical Implications, Annals of Internal Medicine, vol.143, issue.6, pp.446-457, 2005. ,
DOI : 10.7326/0003-4819-143-6-200509200-00009
A Review on the Biology of Cancer Stem Cells, Stem Cell Discovery, vol.04, issue.04, pp.83-89, 2014. ,
DOI : 10.4236/scd.2014.44009
High Motility of Triple-negative Breast Cancer Cells Is Due to Repression of Plakoglobin Gene by Metastasis Modulator Protein SLUG, Journal of Biological Chemistry, vol.1, issue.23, pp.19472-19486, 2012. ,
DOI : 10.1124/mol.107.034561
Cancer Cell Stiffness: Integrated Roles of Three-Dimensional Matrix Stiffness and Transforming Potential, Biophysical Journal, vol.99, issue.7, pp.2048-2057, 2010. ,
DOI : 10.1016/j.bpj.2010.07.051
Doxorubicin in combination with a small TGFbeta inhibitor: a potential novel therapy for metastatic breast cancer in mouse models, PloS One, vol.5, 2010. ,
Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis, International Journal of Cancer, vol.4, 2010. ,
DOI : 10.1128/MCB.18.1.240
Transforming growth factor-beta in breast cancer: too much, too late, Breast Cancer Res. BCR, vol.11, issue.202, 2009. ,
DOI : 10.1186/bcr2224
URL : http://doi.org/10.1186/bcr2224
Targeting the Phosphoinositide-3 (PI3) Kinase Pathway in Breast Cancer, The Oncologist, vol.16, issue.Supplement 1, pp.12-19, 2011. ,
DOI : 10.1634/theoncologist.2011-S1-12
Activin-A signaling promotes epithelial???mesenchymal transition, invasion, and metastatic growth of breast cancer, npj Breast Cancer, vol.19, issue.1, p.15007, 2015. ,
DOI : 10.1038/mt.2011.114
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling, Dev. Camb. Engl, vol.135, pp.2927-2937, 2008. ,
TGF-?? inhibition enhances chemotherapy action against triple-negative breast cancer, Journal of Clinical Investigation, vol.123, issue.3, pp.1348-1358, 2013. ,
DOI : 10.1172/JCI65416DS1
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582135
Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells, Free Radical Biology and Medicine, vol.53, issue.7, pp.1489-1499, 2012. ,
DOI : 10.1016/j.freeradbiomed.2012.06.016
TGF??1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In Vivo, Clinical Cancer Research, vol.17, issue.21, pp.6754-6765, 2011. ,
DOI : 10.1158/1078-0432.CCR-11-0544
IKK?? controls canonical TGF??-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells, Journal of Cell Science, vol.123, issue.24, pp.4231-4239, 2010. ,
DOI : 10.1242/jcs.071100
Induction by transforming growth factor-??1 of epithelial to mesenchymal transition is a rare event in vitro, Breast Cancer Research, vol.273, issue.Pt 24, pp.215-231, 2004. ,
DOI : 10.1074/jbc.273.38.24293
Phosphatases in SMAD regulation, FEBS Letters, vol.11, issue.14, pp.1897-1905, 2012. ,
DOI : 10.1016/j.devcel.2006.10.001
URL : http://doi.org/10.1016/j.febslet.2012.02.001
Cytoskeletal re-arrangement in TGF-??1-induced alveolar epithelial-mesenchymal transition studied by atomic force microscopy and high-content analysis, Nanomedicine: Nanotechnology, Biology and Medicine, vol.8, issue.3, pp.355-364, 2012. ,
DOI : 10.1016/j.nano.2011.06.021
Activin A Mediates Growth Inhibition and Cell Cycle Arrest through Smads in Human Breast Cancer Cells, Cancer Research, vol.65, issue.17, pp.7968-7975, 2005. ,
DOI : 10.1158/0008-5472.CAN-04-3553
Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway, Cancer Chemotherapy and Pharmacology, vol.81, issue.Suppl 3, pp.829-842, 2013. ,
DOI : 10.1111/cas.12004
The transforming growth factor-?? superfamily of receptors, Cytokine & Growth Factor Reviews, vol.15, issue.1, pp.1-11, 2004. ,
DOI : 10.1016/j.cytogfr.2003.10.004
-Methylation of Damaged DNA-binding Protein 2 (DDB2) and Its Function in Nucleotide Excision Repair, Journal of Biological Chemistry, vol.18, issue.23, pp.16046-16056, 2014. ,
DOI : 10.1126/science.1063127
URL : https://hal.archives-ouvertes.fr/jpa-00250938
Stromal EGF and IGF-I Together Modulate Plasticity of Disseminated Triple-Negative Breast Tumors, Cancer Discovery, vol.3, issue.8, pp.922-935, 2013. ,
DOI : 10.1158/2159-8290.CD-13-0041
Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity, Cell, vol.154, issue.1, pp.61-74, 2013. ,
DOI : 10.1016/j.cell.2013.06.005
URL : http://doi.org/10.1016/j.cell.2013.06.005
DDB2 is a novel AR interacting protein and mediates AR ubiquitination/degradation, The International Journal of Biochemistry & Cell Biology, vol.44, issue.11, pp.1952-1961, 2012. ,
DOI : 10.1016/j.biocel.2012.07.023
Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor ?? growth arrest program, Proceedings of the National Academy of Sciences, vol.2, issue.1, pp.992-999, 2001. ,
DOI : 10.1016/S1097-2765(00)80119-7
E2F4/5 and p107 as Smad Cofactors Linking the TGF?? Receptor to c-myc Repression, Cell, vol.110, issue.1, pp.19-32, 2002. ,
DOI : 10.1016/S0092-8674(02)00801-2
URL : http://doi.org/10.1016/s0092-8674(02)00801-2
CTGF enhances the motility of breast cancer cells via an integrin-??vbeta3-ERK1/2-dependent S100A4-upregulated pathway, Journal of Cell Science, vol.120, issue.12, pp.2053-2065, 2007. ,
DOI : 10.1242/jcs.03460
Expression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesis, International Journal of Oncology, vol.38, pp.1741-1747, 2011. ,
DOI : 10.3892/ijo.2011.985
Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation, Nucleic Acids Research, vol.41, issue.18, pp.8403-8420, 2013. ,
DOI : 10.1093/nar/gkt635
URL : http://doi.org/10.1093/nar/gkt635
Breast cancer risk with postmenopausal hormonal treatment, Human Reproduction Update, vol.11, issue.6, pp.545-560, 2005. ,
DOI : 10.1093/humupd/dmi028
Apparent elastic modulus and hysteresis of skeletal muscle cells throughout differentiation, AJP: Cell Physiology, vol.283, issue.4, pp.1219-1227, 2002. ,
DOI : 10.1152/ajpcell.00502.2001
Complexities of TGF-?? Targeted Cancer Therapy, International Journal of Biological Sciences, vol.8, issue.7, pp.964-978, 2012. ,
DOI : 10.7150/ijbs.4564
URL : http://doi.org/10.7150/ijbs.4564
Biophysical properties of human breast cancer cells measured using silicon MEMS resonators and atomic force microscopy, Lab Chip, vol.74, issue.3, pp.839-847, 2015. ,
DOI : 10.1103/PhysRevE.74.021911
Nanomechanical analysis of cells from cancer patients, Nature Nanotechnology, vol.86, issue.12, pp.780-783, 2007. ,
DOI : 10.2214/ajr.178.6.1781411
AFM-based analysis of human metastatic cancer cells, Nanotechnology, vol.19, issue.38, p.384003, 2008. ,
DOI : 10.1088/0957-4484/19/38/384003
Green tea extract selectively targets nanomechanics of live metastatic cancer cells, Nanotechnology, vol.22, issue.21, 2011. ,
DOI : 10.1088/0957-4484/22/21/215101
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151463
The 5???-UTR of DDB2 harbors an IRES element and upregulates translation during stress conditions, Gene, vol.573, issue.1, 2015. ,
DOI : 10.1016/j.gene.2015.07.032
STRAP and Smad7 Synergize in the Inhibition of Transforming Growth Factor beta Signaling, Molecular and Cellular Biology, vol.20, issue.9, pp.3157-3167, 2000. ,
DOI : 10.1128/MCB.20.9.3157-3167.2000
Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention, Oncotarget, vol.5, issue.13, pp.4603-4650, 2014. ,
DOI : 10.18632/oncotarget.2209
Regulatory networks defining EMT during cancer initiation and progression, Nature Reviews Cancer, vol.1611, issue.2, pp.97-110, 2013. ,
DOI : 10.1016/S0005-2736(03)00048-8
Integrins and the actin cytoskeleton, Current Opinion in Cell Biology, vol.19, issue.1, pp.43-50, 2007. ,
DOI : 10.1016/j.ceb.2006.12.013
Integrin signaling to the actin cytoskeleton, Current Opinion in Cell Biology, vol.15, issue.5, pp.572-582, 2003. ,
DOI : 10.1016/S0955-0674(03)00109-1
Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene, The EMBO Journal, vol.17, issue.11, pp.3091-3100, 1998. ,
DOI : 10.1093/emboj/17.11.3091
Distinct endocytic pathways regulate TGF-?? receptor signalling and turnover, Nature Cell Biology, vol.20, issue.5, pp.410-421, 2003. ,
DOI : 10.1091/mbc.7.11.1825
Decreased expression of intercellular adhesion molecule-1 (ICAM-1) and urokinase-type plasminogen activator receptor (uPAR) is associated with tumor cell spreading in vivo, Clinical and Experimental Metastasis, vol.19, issue.5, pp.437-444, 2002. ,
DOI : 10.1023/A:1016329802327
Temporal and hormonal regulation of inhibin protein and subunit mRNA expression by post-natal and immature rat ovaries, Journal of Endocrinology, vol.166, issue.2, pp.339-354, 2000. ,
DOI : 10.1677/joe.0.1660339
uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies, Breast Cancer Research, vol.108, issue.Suppl, p.428, 2014. ,
DOI : 10.1038/bjc.2013.62
FAM/USP9x, a Deubiquitinating Enzyme Essential for TGF?? Signaling, Controls Smad4 Monoubiquitination, Cell, vol.136, issue.1, pp.123-135, 2009. ,
DOI : 10.1016/j.cell.2008.10.051
URL : http://doi.org/10.1016/j.cell.2008.10.051
Identification of a Novel Luminal Molecular Subtype of Breast Cancer, PLoS ONE, vol.12, issue.7, 2014. ,
DOI : 10.1371/journal.pone.0103514.s008
Smurf1 Interacts with Transforming Growth Factor-?? Type I Receptor through Smad7 and Induces Receptor Degradation, Journal of Biological Chemistry, vol.112, issue.16, pp.12477-12480, 2001. ,
DOI : 10.1016/S1097-2765(00)00134-9
Breast Cancer Risks and Risk Prediction Models, Breast Care, vol.10, issue.1, pp.7-12, 2015. ,
DOI : 10.1159/000376600
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395818
DDB2: A Novel Regulator of NF-??B and Breast Tumor Invasion, Cancer Research, vol.73, issue.16, pp.5040-5052, 2013. ,
DOI : 10.1158/0008-5472.CAN-12-3655
TIF1?? requires sumoylation to exert its repressive activity on TGF?? signaling, Journal of Cell Science, vol.126, issue.16, pp.3713-3723, 2013. ,
DOI : 10.1242/jcs.126748
A kinase subdomain of transforming growth factor-?? (TGF-??) type I receptor determines the TGF-?? intracellular signaling specificity, The EMBO Journal, vol.16, issue.13, pp.3912-3923, 1997. ,
DOI : 10.1093/emboj/16.13.3912
Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15Ink4B transcription in response to TGF-??, The EMBO Journal, vol.94, issue.19, pp.5178-5193, 2000. ,
DOI : 10.1128/MCB.19.9.5913
Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGFbeta complexes containing LTBP-1, FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol, vol.19, pp.1798-1808, 2005. ,
Profiling of Estrogen Up- and Down-Regulated Gene Expression in Human Breast Cancer Cells: Insights into Gene Networks and Pathways Underlying Estrogenic Control of Proliferation and Cell Phenotype, Endocrinology, vol.144, issue.10, pp.4562-4574, 2003. ,
DOI : 10.1210/en.2003-0567
Common structural traits for cystine knot domain of the TGF?? superfamily of proteins and three-fingered ectodomain of their cellular receptors, Cellular and Molecular Life Sciences, vol.9, issue.Pt 10, pp.3437-3451, 2011. ,
DOI : 10.1038/nrc2622
Polymerizing Actin Fibers Position Integrins Primed to Probe for Adhesion Sites, Science, vol.315, issue.5814, pp.992-995, 2007. ,
DOI : 10.1126/science.1137904
Ubiquitin Ligase Nedd4L Targets Activated Smad2/3 to Limit TGF-?? Signaling, Molecular Cell, vol.36, issue.3, pp.457-468, 2009. ,
DOI : 10.1016/j.molcel.2009.09.043
URL : http://doi.org/10.1016/j.molcel.2009.09.043
C/EBP?? at the core of the TGF?? cytostatic response and its evasion in metastatic breast cancer cells, Cancer Cell, vol.10, issue.3, pp.203-214, 2006. ,
DOI : 10.1016/j.ccr.2006.07.019
Activin Receptor-Like Kinases: Structure, Function and Clinical Implications, Endocrine, Metabolic & Immune Disorders - Drug Targets, vol.6, issue.1, pp.45-58, 2006. ,
DOI : 10.2174/187153006776056585
A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene, Cell Growth Differ. Mol. Biol. J. Am. Assoc. Cancer Res, vol.7, pp.469-480, 1996. ,
Viscoelastic Properties of the Cell Nucleus, Biochemical and Biophysical Research Communications, vol.269, issue.3, 2000. ,
DOI : 10.1006/bbrc.2000.2360
Hallmarks of Cancer: The Next Generation, Cell, vol.144, issue.5, pp.646-674, 2011. ,
DOI : 10.1016/j.cell.2011.02.013
DDB, a Putative DNA Repair Protein, Can Function as a Transcriptional Partner of E2F1, Molecular and Cellular Biology, vol.18, issue.1, pp.240-249, 1998. ,
DOI : 10.1128/MCB.18.1.240
Hypoxia-activated Smad3-specific Dephosphorylation by PP2A, Journal of Biological Chemistry, vol.77, issue.6, 2010. ,
DOI : 10.1074/jbc.M206535200
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823515
Role of Smads in TGF?? signaling, Cell and Tissue Research, vol.282, issue.1, pp.21-36, 2012. ,
DOI : 10.1074/jbc.M700636200
Mode of action of docetaxel ??? a basis for combination with novel anticancer agents, Cancer Treatment Reviews, vol.29, issue.5, pp.407-415, 2003. ,
DOI : 10.1016/S0305-7372(03)00097-5
Comprehensive analysis of ??-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/??-catenin signaling, BMC Genomics, vol.15, issue.1, p.74, 2014. ,
DOI : 10.1093/nar/30.1.207
Antagonistic regulation of EMT by TIF1?? and Smad4 in mammary epithelial cells, EMBO reports, vol.12, issue.7, pp.665-672, 2011. ,
DOI : 10.1371/journal.pgen.1000575
URL : https://hal.archives-ouvertes.fr/hal-00835151
Structural studies of the TGF-??s and their receptors - insights into evolution of the TGF-?? superfamily, FEBS Letters, vol.9, issue.14, pp.1860-1870, 2012. ,
DOI : 10.1016/j.devcel.2005.09.008
Anthrazykline in der Krebstherapie, Drugs, vol.54, issue.Supplement 4, pp.1-7, 2012. ,
DOI : 10.2165/00003495-199700544-00003
Translational regulation of inhibin ??A by TGF?? via the RNA-binding protein hnRNP E1 enhances the invasiveness of epithelial-to-mesenchymal transitioned cells, Oncogene, vol.112, issue.13, 2015. ,
DOI : 10.1089/scd.2009.0430
Regulation of TGF-?? receptor activity, Cell & Bioscience, vol.2, issue.1, p.9, 2012. ,
DOI : 10.1182/blood-2007-05-092718
URL : http://doi.org/10.1186/2045-3701-2-9
Crystal Structure of the Cytoplasmic Domain of the Type I TGF ?? Receptor in Complex with FKBP12, Cell, vol.96, issue.3, pp.425-436, 1999. ,
DOI : 10.1016/S0092-8674(00)80555-3
Integrins in Cell Migration, Cold Spring Harbor Perspectives in Biology, vol.3, issue.9, 2011. ,
DOI : 10.1101/cshperspect.a005074
Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair, Proceedings of the National Academy of Sciences, vol.385, issue.2, 1999. ,
DOI : 10.1016/S0921-8777(97)00029-3
The roles of TGF-?? signaling in carcinogenesis and breast cancer metastasis, Breast Cancer, vol.100, issue.2, pp.118-124, 2012. ,
DOI : 10.1093/jnci/djn123
Stoichiometry of Active Smad-Transcription Factor Complexes on DNA, Journal of Biological Chemistry, vol.14, issue.52, pp.51008-51016, 2002. ,
DOI : 10.1016/S1359-6101(00)00031-9
Human DDB2 splicing variants are dominant negative inhibitors of UV-damaged DNA repair, Biochemical and Biophysical Research Communications, vol.314, issue.4, pp.1036-1043, 2004. ,
DOI : 10.1016/j.bbrc.2004.01.003
Triple-Negative Breast Cancer, The Cancer Journal, vol.16, issue.1, pp.53-61, 2010. ,
DOI : 10.1097/PPO.0b013e3181d24ff7
DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen, Proceedings of the National Academy of Sciences, vol.100, issue.7, pp.2052-2057, 2004. ,
DOI : 10.1667/0033-7587(2000)154[0342:IOPMBI]2.0.CO;2
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC357050
Ddb2 is a haploinsufficient tumor suppressor and controls spontaneous germ cell apoptosis, Human Molecular Genetics, vol.16, issue.13, pp.1578-1586, 2007. ,
DOI : 10.1093/hmg/ddm107
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.582.6217
Blockade of Wnt/??-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype, Scientific Reports, vol.66, issue.1, 2015. ,
DOI : 10.1158/0008-5472.CAN-06-0825
Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer, Cancer Res, vol.63, pp.3783-3790, 2003. ,
TGF-?? is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion, Cell Death and Disease, vol.260, issue.10, 2014. ,
DOI : 10.1016/j.cell.2013.06.005
Resistance to transforming growth factor beta and activin due to reduced receptor expression in human breast tumor cell lines, Cell Growth Differ, vol.6, p.1151, 1995. ,
Smad7 Inhibits Transforming Growth Factor-?? Family Type I Receptors through Two Distinct Modes of Interaction, Journal of Biological Chemistry, vol.10, issue.40, pp.30804-30813, 2010. ,
DOI : 10.1074/jbc.C300028200
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945574
The type I TGF-?? receptor is covalently modified and regulated by sumoylation, Nature Cell Biology, vol.3, issue.6, pp.654-664, 2008. ,
DOI : 10.1083/jcb.149.3.667
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649123
A Self-Enabling TGF?? Response Coupled to Stress Signaling, Molecular Cell, vol.11, issue.4, pp.915-926, 2003. ,
DOI : 10.1016/S1097-2765(03)00109-6
URL : http://doi.org/10.1016/s1097-2765(03)00109-6
Damaged DNA Binding Protein 2 Plays a Role in Breast Cancer Cell Growth, PLoS ONE, vol.48, issue.4, 2002. ,
DOI : 10.1371/journal.pone.0002002.s003
URL : https://hal.archives-ouvertes.fr/hal-00276571
Role of manganese superoxide dismutase on growth and invasive properties of human estrogen-independent breast cancer cells, Breast Cancer Research and Treatment, vol.8, issue.2, pp.203-215, 2008. ,
DOI : 10.1128/MCB.17.7.3629
A phase I/II trial of intraoperative breast radiotherapy in an Asian population: 5-year results of local control and cosmetic outcome, Radiation Oncology, vol.104, issue.4, p.150, 2015. ,
DOI : 10.1097/00006534-199910000-00031
TGF-??: from latent to active, Microbes and Infection, vol.1, issue.15, pp.1255-1263, 1999. ,
DOI : 10.1016/S1286-4579(99)00259-2
Transforming Growth Factor Beta Receptor I Inhibitor Sensitizes Drug-resistant Pancreatic Cancer Cells to Gemcitabine, Anticancer Res, vol.32, pp.799-806, 2012. ,
Molecular Profiling for Breast Cancer: A Comprehensive Review, Biomark. Cancer, vol.5, pp.61-70, 2013. ,
Autophagy Is Activated by TGF-?? and Potentiates TGF-??-Mediated Growth Inhibition in Human Hepatocellular Carcinoma Cells, Cancer Research, vol.69, issue.23, pp.8844-8852, 2009. ,
DOI : 10.1158/0008-5472.CAN-08-4401
The actin binding protein destrin is associated with growth and perineural invasion of pancreatic cancer, Pancreatology, vol.12, issue.4, 2012. ,
DOI : 10.1016/j.pan.2012.05.012
Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts, Proc. Natl. Acad. Sci. U. S. A. 107, 2010. ,
Reversible Disruption of Cell-Matrix and Cell-Cell Interactions by Overexpression of Sialomucin Complex, Journal of Biological Chemistry, vol.151, issue.52, 1997. ,
DOI : 10.1002/jcp.1041510304
Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter, Journal of Biological Chemistry, vol.16, issue.7, pp.4883-4891, 2002. ,
DOI : 10.1038/40906
TGF-?? ??? an excellent servant but a bad master, Journal of Translational Medicine, vol.10, issue.1, p.183, 2012. ,
DOI : 10.1016/j.bone.2010.05.036
URL : http://doi.org/10.1186/1479-5876-10-183
NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-?? (transforming growth factor-??) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-?? type I receptor, Biochemical Journal, vol.386, issue.3, pp.461-470, 2005. ,
DOI : 10.1042/BJ20040738
Transforming Growth Factor-?? Induces Nuclear Import of Smad3 in an Importin-??1 and Ran-dependent Manner, Molecular Biology of the Cell, vol.12, issue.4, pp.1079-1091, 2001. ,
DOI : 10.1091/mbc.12.4.1079
Atomic force microscopy probing of cell elasticity, Micron, vol.38, issue.8, pp.824-833, 1993. ,
DOI : 10.1016/j.micron.2007.06.011
Molecular mechanisms of epithelial???mesenchymal transition, Nature Reviews Molecular Cell Biology, vol.22, issue.3, pp.178-196, 2014. ,
DOI : 10.1016/j.ccr.2012.10.012
The ID proteins: master regulators of cancer stem cells and tumour aggressiveness, Nature Reviews Cancer, vol.13, issue.2, pp.77-91, 2014. ,
DOI : 10.1016/j.devcel.2007.05.014
Cancer cell recognition ??? Mechanical phenotype, Micron, vol.43, issue.12, pp.1259-1266, 1993. ,
DOI : 10.1016/j.micron.2012.01.019
Cancer cell detection in tissue sections using AFM, Archives of Biochemistry and Biophysics, vol.518, issue.2, pp.151-156, 2012. ,
DOI : 10.1016/j.abb.2011.12.013
Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit? Breast Cancer Res, 2009. ,
Chemoresistance to doxorubicin induces epithelialmesenchymal transition via upregulation of transforming growth factor ? signaling in HCT116 colon cancer cells, Mol. Med. Rep, vol.12, pp.192-198, 2015. ,
Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model, PLoS ONE, vol.4, issue.11, p.7965, 2009. ,
DOI : 10.1371/journal.pone.0007965.g006
Robust Strategies for Automated AFM Force Curve Analysis???II: Adhesion-Influenced Indentation of Soft, Elastic Materials, Journal of Biomechanical Engineering, vol.129, issue.6, pp.904-912, 2007. ,
DOI : 10.1115/1.2800826
SUMO-1/Ubc9 Promotes Nuclear Accumulation and Metabolic Stability of Tumor Suppressor Smad4, Journal of Biological Chemistry, vol.114, issue.33, pp.31043-31048, 2003. ,
DOI : 10.1074/jbc.M301755200
PPM1A Functions as a Smad Phosphatase to Terminate TGF?? Signaling, Cell, vol.125, issue.5, pp.915-928, 2006. ,
DOI : 10.1016/j.cell.2006.03.044
Biophysical Characterization of Bladder Cancer Cells with Different Metastatic Potential, Cell Biochemistry and Biophysics, vol.5, issue.78, pp.241-246, 2014. ,
DOI : 10.1038/ncb1037
TAp63?? enhances nucleotide excision repair through transcriptional regulation of DNA repair genes, DNA Repair, vol.11, issue.2, pp.167-176, 2012. ,
DOI : 10.1016/j.dnarep.2011.10.016
Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT, Proceedings of the National Academy of Sciences, vol.11, issue.1, pp.9791-9796, 2003. ,
DOI : 10.1016/S1097-2765(03)00014-5
5-Fluorouracil: mechanisms of action and clinical strategies, Nature Reviews Cancer, vol.3, issue.5, pp.330-338, 2003. ,
DOI : 10.1038/nrc1074
PARP-1 Attenuates Smad-Mediated Transcription, Molecular Cell, vol.40, issue.4, pp.521-532, 2010. ,
DOI : 10.1016/j.molcel.2010.10.029
Intertwining of Activin A and TGF?? Signaling: Dual Roles in Cancer Progression and Cancer Cell Invasion, Cancers, vol.60, issue.1, pp.70-91, 2014. ,
DOI : 10.1677/joe.1.05978
DDB2 promotes chromatin decondensation at UV-induced DNA damage, The Journal of Cell Biology, vol.60, issue.2, pp.267-281, 2012. ,
DOI : 10.1128/MCB.00695-06
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328393
Predictive role of molecular subtypes in response to neoadjuvant chemotherapy in breast cancer patients in Northeast China. Asian Pac, J. Cancer Prev. APJCP, vol.12, pp.2411-2417, 2011. ,
Responsiveness to Transforming Growth Factor-?? (TGF-??)-Mediated Growth Inhibition Is a Function of Membrane-Bound TGF-?? Type II Receptor in Human Breast Cancer Cells, Gene Expression, vol.9, issue.4, pp.157-171, 2001. ,
DOI : 10.3727/000000001783992560
Structural determinants of Smad function in TGF-?? signaling, Trends in Biochemical Sciences, vol.40, issue.6, pp.296-308, 2015. ,
DOI : 10.1016/j.tibs.2015.03.012
During hematopoiesis, expression of FLRG, a novel activin A ligand, is regulated by TGF-??, Experimental Hematology, vol.29, issue.3, pp.301-308, 2001. ,
DOI : 10.1016/S0301-472X(00)00675-5
Histological, molecular and functional subtypes of breast cancers, Cancer Biology & Therapy, vol.55, issue.10, pp.955-960, 2010. ,
DOI : 10.1038/nm.2000
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047091
Understanding nucleotide excision repair and its roles in cancer and ageing, Nature Reviews Molecular Cell Biology, vol.286, issue.7, pp.465-481, 2014. ,
DOI : 10.1074/jbc.M111.232041
Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo, Molecular and Cellular Biology, vol.21, issue.20, pp.6782-6795, 2001. ,
DOI : 10.1128/MCB.21.20.6782-6795.2001
TGF?? signalling in context, Nature Reviews Molecular Cell Biology, vol.18, issue.10, pp.616-630, 2012. ,
DOI : 10.1016/j.ccr.2010.10.023
Smad transcription factors, Genes & Development, vol.19, issue.23, pp.2783-2810, 2005. ,
DOI : 10.1101/gad.1350705
Growth Differentiation Factor-9 Signaling Is Mediated by the Type I Receptor, Activin Receptor-Like Kinase 5, Molecular Endocrinology, vol.18, issue.3, pp.653-665, 2004. ,
DOI : 10.1210/me.2003-0393
A novel cis -acting element from the 3???UTR of DNA damage-binding protein 2 mRNA links transcriptional and post-transcriptional regulation of gene expression, Nucleic Acids Research, vol.41, issue.11, pp.5692-5703, 2013. ,
DOI : 10.1093/nar/gkt279
Inhibition of PAI-1 expression in breast cancer carcinoma cells by siRNA at nanomolar range, Biochimie, vol.89, issue.10, pp.1228-1233, 2007. ,
DOI : 10.1016/j.biochi.2007.03.017
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-?? signaling, Journal of Clinical Investigation, vol.119, issue.9, pp.2678-2690, 2009. ,
DOI : 10.1172/JCI37815DS1
Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression, Journal of Mammary Gland Biology and Neoplasia, vol.63, issue.10, pp.117-134, 2010. ,
DOI : 10.1172/JCI0215234
Gene Expression in Human Breast Cancer Cells, Journal of Biological Chemistry, vol.10, issue.21, pp.14165-14176, 2009. ,
DOI : 10.1002/(SICI)1098-2744(199911)26:3<180::AID-MC7>3.0.CO;2-4
Gene Expression in Human Breast Cancer Cells, Journal of Biological Chemistry, vol.10, issue.21, pp.14165-14176, 2009. ,
DOI : 10.1002/(SICI)1098-2744(199911)26:3<180::AID-MC7>3.0.CO;2-4
Transforming growth factor-??1 is the predominant isoform required for breast cancer cell outgrowth in bone, Oncogene, vol.16, issue.7, pp.1005-1015, 2009. ,
DOI : 10.2174/187152007781668689
The regulation of TGFbeta signal transduction, 2009. ,
Coordination of TGF-?? Signaling by Ubiquitylation, Molecular Cell, vol.51, issue.5, pp.555-556, 2013. ,
DOI : 10.1016/j.molcel.2013.08.034
The integrin ??v??8 mediates epithelial homeostasis through MT1-MMP???dependent activation of TGF-??1, The Journal of Cell Biology, vol.14, issue.3, pp.493-507, 2002. ,
DOI : 10.1074/jbc.275.6.4183
Non-Smad signaling pathways, Cell and Tissue Research, vol.274, issue.1, pp.11-20, 2012. ,
DOI : 10.1074/jbc.274.45.32258
Promiscuity and specificity in BMP receptor activation, FEBS Letters, vol.20, issue.14, pp.1846-1859, 2012. ,
DOI : 10.1016/j.cytogfr.2009.10.008
Critical Role of CD11a (LFA-1) in Therapeutic Efficacy of Systemically Transferred Antitumor Effector T Cells, Cellular Immunology, vol.192, issue.2, pp.122-132, 1999. ,
DOI : 10.1006/cimm.1998.1439
Atomic force microscopy: a nanoscopic window on the cell surface, Trends in Cell Biology, vol.21, issue.8, pp.461-469, 2011. ,
DOI : 10.1016/j.tcb.2011.04.008
activin subunits (inhibin-alpha, -betaA and -betaB) are differentially expressed in human breast cancer and their metastasis, Oncol. Rep, vol.13, pp.81-88 ,
The Xeroderma Pigmentosum Group E Gene Product DDB2 Is a Specific Target of Cullin 4A in Mammalian Cells, Molecular and Cellular Biology, vol.21, issue.20, pp.6738-6747, 2001. ,
DOI : 10.1128/MCB.21.20.6738-6747.2001
Targeting the TGF?? pathway for cancer therapy, Pharmacology & Therapeutics, vol.147, pp.22-31, 2015. ,
DOI : 10.1016/j.pharmthera.2014.11.001
Basal transcriptional regulation of human damage-specific DNA-binding protein genes DDB1 and DDB2 by Sp1, E2F, N-myc and NF1 elements, Nucleic Acids Research, vol.31, issue.2, pp.562-569, 2003. ,
DOI : 10.1093/nar/gkg152
The Fluid???Mosaic Model of Membrane Structure: Still relevant to understanding the structure, function and dynamics of biological membranes after more than 40years, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1838, issue.6, pp.1451-1466, 2014. ,
DOI : 10.1016/j.bbamem.2013.10.019
The Life History of 21 Breast Cancers, Cell, vol.149, issue.5, pp.994-1007, 2012. ,
DOI : 10.1016/j.cell.2012.04.023
Mutational Processes Molding the Genomes of 21 Breast Cancers, Cell, vol.149, issue.5, pp.979-993, 2012. ,
DOI : 10.1016/j.cell.2012.04.024
A dual role of activin A in regulating immunoglobulin production of B cells, Journal of Leukocyte Biology, vol.83, issue.6, pp.1451-1458, 2008. ,
DOI : 10.1189/jlb.1007710
Expression of intercellular adhesion molecule-1 in invasive breast cancer reflects low growth potential, negative lymph node involvement, and good prognosis, Clin. Cancer Res. Off. J. Am. Assoc. Cancer Res, vol.4, pp.31-36, 1998. ,
Atomic force microscope-based single cell force spectroscopy of breast cancer cell lines: An approach for evaluating cellular invasion, Journal of Biomechanics, vol.47, issue.13, pp.3373-3379, 2014. ,
DOI : 10.1016/j.jbiomech.2014.08.002
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion, Cell, vol.121, issue.3, pp.335-348, 2005. ,
DOI : 10.1016/j.cell.2005.02.034
Roles of TGF?? in metastasis, Cell Research, vol.49, issue.1, pp.89-102, 2009. ,
DOI : 10.1038/nature03799
A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer, New England Journal of Medicine, vol.351, issue.27, pp.2817-2826, 2004. ,
DOI : 10.1056/NEJMoa041588
Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes, Journal of Clinical Oncology, vol.27, issue.8, pp.1160-1167, 2009. ,
DOI : 10.1200/JCO.2008.18.1370
Cell Cycle Arrest, Cancer Research, vol.64, issue.1, pp.423-428, 2004. ,
DOI : 10.1158/0008-5472.CAN-03-2446
Molecular Stratification of Triple-Negative Breast Cancers, The Oncologist, vol.15, issue.Supplement 5, pp.39-48, 2010. ,
DOI : 10.1634/theoncologist.2010-S5-39
Molecular Stratification of Triple-Negative Breast Cancers ,
Molecular portraits of human breast tumours, Nature, vol.406, issue.6797, pp.747-752, 2000. ,
DOI : 10.1038/35021093
Superoxide anion: Oncogenic reactive oxygen species?, The International Journal of Biochemistry & Cell Biology, vol.39, issue.7-8, pp.1297-1304, 2007. ,
DOI : 10.1016/j.biocel.2007.04.007
Detection of lipopolysaccharide induced inflammatory responses in RAW264.7 macrophages using atomic force microscope, Micron, vol.65, pp.1-9, 1993. ,
DOI : 10.1016/j.micron.2014.03.012
PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1, The Journal of Cell Biology, vol.1, issue.2, pp.235-249, 2012. ,
DOI : 10.1128/MCB.00695-06
The nanomechanical signature of breast cancer, Nature Nanotechnology, vol.12, issue.11, pp.757-765, 2012. ,
DOI : 10.1016/j.jsb.2011.03.011
Variable expression levels of keratin and vimentin reveal differential EMT status of circulating tumor cells and correlation with clinical characteristics and outcome of patients with metastatic breast cancer, BMC Cancer, vol.2011, issue.5, p.399, 2015. ,
DOI : 10.1155/2011/252361
Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity, Nature Communications, vol.252, p.3695, 2014. ,
DOI : 10.1073/pnas.0511160103
DDB2 is involved in ubiquitination and degradation of PAQR3 and regulates tumorigenesis of gastric cancer cells, Biochemical Journal, vol.469, issue.3, pp.469-480, 2015. ,
DOI : 10.1042/BJ20150253
Changes in cholesterol levels in the plasma membrane modulate cell signaling and regulate cell adhesion and migration on fibronectin, Cell Motility and the Cytoskeleton, vol.2, issue.3, pp.199-216, 2007. ,
DOI : 10.1002/cm.20176
Oncogenes induce a vimentin filament collapse mediated by HDAC6 that is linked to cell stiffness, Proceedings of the National Academy of Sciences, vol.22, issue.8, pp.1515-1520, 2014. ,
DOI : 10.1091/mbc.E10-08-0699
Elastic Membrane Heterogeneity of Living Cells Revealed by Stiff Nanoscale Membrane Domains, Biophysical Journal, vol.94, issue.4, pp.1521-1532, 2008. ,
DOI : 10.1529/biophysj.107.112862
Stiffness Tomography by Atomic Force Microscopy, Biophysical Journal, vol.97, issue.2, pp.674-677, 2009. ,
DOI : 10.1016/j.bpj.2009.05.010
DDB2, an Essential Mediator of Premature Senescence, Molecular and Cellular Biology, vol.30, issue.11, pp.2681-2692, 2010. ,
DOI : 10.1128/MCB.01480-09
Damaged DNA Binding Protein 2 in Reactive Oxygen Species (ROS) Regulation and Premature Senescence, International Journal of Molecular Sciences, vol.37, issue.12, pp.11012-11026, 2012. ,
DOI : 10.3892/ijo_00000702
DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer, Cancer Research, vol.73, issue.12, pp.3771-3782, 2013. ,
DOI : 10.1158/0008-5472.CAN-12-4069
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686976
TGF-??/TGF-?? receptor system and its role in physiological and pathological conditions, Clinical Science, vol.1, issue.6, pp.233-251, 1979. ,
DOI : 10.1023/A:1008336703450
Estrogen Regulation of Anti-Apoptotic Bcl-2 Family Member Mcl-1 Expression in Breast Cancer Cells, PLoS ONE, vol.287, issue.6, 2014. ,
DOI : 10.1371/journal.pone.0100364.s001
Structural Basis of UV DNA-Damage Recognition by the DDB1???DDB2 Complex, Cell, vol.135, issue.7, pp.1213-1223, 2008. ,
DOI : 10.1016/j.cell.2008.10.045
Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation, Cell, vol.117, issue.2, pp.211-223, 2004. ,
DOI : 10.1016/S0092-8674(04)00298-3
CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases, Open Biology, vol.81, issue.6, 2014. ,
DOI : 10.1146/annurev-biochem-060310-170328
GADD34???PP1c recruited by Smad7 dephosphorylates TGF?? type I receptor, The Journal of Cell Biology, vol.14, issue.2, pp.291-300, 2004. ,
DOI : 10.1016/S0962-8924(99)01579-2
Pathogenic Role of Connective Tissue Growth Factor (CTGF/CCN2) in Osteolytic Metastasis of Breast Cancer, Journal of Bone and Mineral Research, vol.9, issue.7, pp.1045-1059, 2006. ,
DOI : 10.1128/MCB.19.4.2958
The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents, Cancer Treatment Reviews, vol.37, issue.1, pp.63-74, 2011. ,
DOI : 10.1016/j.ctrv.2010.05.001
TGF-? induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R- Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer, Genes Cancer, vol.5, pp.320-336, 2014. ,
Probing elasticity and adhesion of live cells by atomic force microscopy indentation, European Biophysics Journal, vol.27, issue.6, pp.935-945, 2008. ,
DOI : 10.1098/rspa.1971.0141
Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: Focus on the role and impact of proteoglycans, Matrix Biology, vol.35, pp.182-193, 2014. ,
DOI : 10.1016/j.matbio.2013.09.002
Snail Promotes Epithelial Mesenchymal Transition in Breast Cancer Cells in Part via Activation of Nuclear ERK2, PLoS ONE, vol.104, issue.2, 2014. ,
DOI : 10.1371/journal.pone.0104987.s005
Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells, The Journal of Steroid Biochemistry and Molecular Biology, vol.118, issue.4-5, pp.219-230, 2010. ,
DOI : 10.1016/j.jsbmb.2009.09.018
Repeated observation of breast tumor subtypes in independent gene expression data sets, Proceedings of the National Academy of Sciences, vol.360, issue.9338, pp.8418-8423, 2003. ,
DOI : 10.1016/S0140-6736(02)11087-7
The type I TGF-?? receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner, Nature Cell Biology, vol.75, issue.10, pp.1199-1207, 2008. ,
DOI : 10.4161/cc.5.23.3523
Inhibin resistance is associated with aggressive tumorigenicity of ovarian cancer cells, Mol. Cancer Res. MCR, vol.3, pp.50-61, 2005. ,
DDB2 decides cell fate following DNA damage, Proceedings of the National Academy of Sciences, vol.24, issue.7, pp.10690-10695, 2009. ,
DOI : 10.1128/MCB.24.7.2649-2661.2004
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705559
p21 Cooperates with DDB2 Protein in Suppression of Ultraviolet Ray-induced Skin Malignancies, Journal of Biological Chemistry, vol.55, issue.5, pp.3019-3028, 2012. ,
DOI : 10.1038/embor.2010.46
Cooperative Binding of Smad Proteins to Two Adjacent DNA Elements in the Plasminogen Activator Inhibitor-1 Promoter Mediates Transforming Growth Factor ??-induced Smad-dependent Transcriptional Activation, Journal of Biological Chemistry, vol.10, issue.14, pp.9431-9441, 1999. ,
DOI : 10.1073/pnas.95.16.9506
Negative Feedback Regulation of TGF- Signaling by the SnoN Oncoprotein, Science, vol.286, issue.5440, pp.771-774, 1999. ,
DOI : 10.1126/science.286.5440.771
Damaged DNA-binding protein 2 (DDB2) protects against UV irradiation in human cells and Drosophila, Journal of Biomedical Science, vol.17, issue.1, p.27, 2010. ,
DOI : 10.1186/1423-0127-17-27
Biomechanics and biophysics of cancer cells???, Acta Biomaterialia, vol.3, issue.4, pp.413-438, 2007. ,
DOI : 10.1016/j.actbio.2007.04.002
STRING v10: protein-protein interaction networks, integrated over the tree of life, Nucleic Acids Research, vol.43, issue.D1, pp.447-452, 2015. ,
DOI : 10.1093/nar/gku1003
DDB2 Complex-Mediated Ubiquitylation around DNA Damage Is Oppositely Regulated by XPC and Ku and Contributes to the Recruitment of XPA, Molecular and Cellular Biology, vol.30, issue.11, pp.2708-2723, 2010. ,
DOI : 10.1128/MCB.01460-09
DDB2 Complex-Mediated Ubiquitylation around DNA Damage Is Oppositely Regulated by XPC ,
DOI : 10.1128/mcb.01460-09
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876528
p53 Binds and Activates the Xeroderma Pigmentosum DDB2 Gene in Humans but Not Mice, Molecular and Cellular Biology, vol.22, issue.10, pp.3247-3254, 2002. ,
DOI : 10.1128/MCB.22.10.3247-3254.2002
Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein, DNA Repair, vol.1, issue.8, pp.601-616, 2002. ,
DOI : 10.1016/S1568-7864(02)00052-6
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894533/pdf
BRCA1/2 associated hereditary breast cancer, Journal of Zhejiang University SCIENCE B, vol.9, issue.2, pp.85-89, 2008. ,
DOI : 10.1631/jzus.B0710617
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225488
Effects of Type I Collagen and Fibronectin on Regulation of Breast Cancer Cell Biological and Biomechanical Characteristics, J. Med. Biol. Engeneering, pp.62-68, 2012. ,
p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer, Cell, vol.158, issue.3, pp.579-592, 2014. ,
DOI : 10.1016/j.cell.2014.05.051
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119474
Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer, Annals of Oncology, vol.18, issue.6, pp.977-984, 2007. ,
DOI : 10.1093/annonc/mdl475
Gene expression profiling predicts clinical outcome of breast cancer, Nature, vol.415, issue.6871, pp.530-536, 2002. ,
DOI : 10.1038/415530a
Loss of Myoferlin Redirects Breast Cancer Cell Motility towards Collective Migration, PLoS ONE, vol.182, issue.2, p.86110, 2014. ,
DOI : 10.1371/journal.pone.0086110.s003
Insulin- Like Growth Factor and Epidermal Growth Factor Signaling in Breast Cancer Cell Growth, Focus on Endocrine Resistant Disease. Anal. Cell. Pathol, p.975495, 2015. ,
IDENTIFICATION OF AN ACTIVIN-FOLLISTATIN GROWTH MODULATORY SYSTEM IN THE HUMAN PROSTATE, The Journal of Urology, vol.161, pp.1378-1384, 1999. ,
DOI : 10.1097/00005392-199904000-00099
Emerging patterns of somatic mutations in cancer, Nature Reviews Genetics, vol.486, issue.10, pp.703-718, 2013. ,
DOI : 10.1016/j.cell.2012.08.024
Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer, Journal of Clinical Investigation, vol.123, issue.8, pp.3190-3200, 2013. ,
DOI : 10.1172/JCI70212DS1
Roles for Growth Factors in Cancer Progression, Physiology, vol.25, issue.2, pp.85-101, 2010. ,
DOI : 10.1152/physiol.00045.2009
A Smad Transcriptional Corepressor, Cell, vol.97, issue.1, pp.29-39, 1999. ,
DOI : 10.1016/S0092-8674(00)80712-6
Multiple Modes of Repression by the Smad Transcriptional Corepressor TGIF, Journal of Biological Chemistry, vol.19, issue.52, pp.37105-37110, 1999. ,
DOI : 10.1128/MCB.19.7.5134
The Smad transcriptional corepressor TGIF recruits mSin3, Cell Growth Differ. Mol. Biol. J. Am, 2001. ,
DOI : 10.1016/s0092-8674(00)80712-6
URL : http://doi.org/10.1016/s0092-8674(00)80712-6
Small C-terminal Domain Phosphatases Dephosphorylate the Regulatory Linker Regions of Smad2 and Smad3 to Enhance Transforming Growth Factor-?? Signaling, Journal of Biological Chemistry, vol.269, issue.50, pp.38365-38375, 2006. ,
DOI : 10.1006/dbio.2001.0420
Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski, Cell, vol.111, issue.3, pp.357-367, 2002. ,
DOI : 10.1016/S0092-8674(02)01006-1
The biology of activin: recent advances in structure, regulation and function, Journal of Endocrinology, vol.202, issue.1, pp.1-12, 2009. ,
DOI : 10.1677/JOE-08-0549
Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features, Cancer Res, vol.61, pp.8917-8923, 2001. ,
Alterations of Smad Signaling in Human Breast Carcinoma Are Associated with Poor Outcome A Tissue Microarray Study, Cancer Res, vol.62, pp.497-505, 2002. ,
14-3-3?? Turns TGF-?????s Function from Tumor Suppressor to Metastasis Promoter in Breast Cancer by Contextual Changes of Smad Partners from p53 to Gli2, Cancer Cell, vol.27, issue.2, pp.177-192, 2015. ,
DOI : 10.1016/j.ccell.2014.11.025
Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells, PLoS ONE, vol.7, issue.10, p.46609, 2012. ,
DOI : 10.1371/journal.pone.0046609.s005
Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-?????dependent cancer metastasis, Journal of Clinical Investigation, vol.124, issue.2, pp.564-579, 2014. ,
DOI : 10.1172/JCI71104DS1
Protein Domain-Level Landscape of Cancer-Type-Specific Somatic Mutations, PLOS Computational Biology, vol.4, issue.6, 2015. ,
DOI : 10.1371/journal.pcbi.1004147.s008
Biological subtypes of breast cancer: Prognostic and therapeutic implications, World Journal of Clinical Oncology, vol.5, issue.3, pp.412-424, 2014. ,
DOI : 10.5306/wjco.v5.i3.412
EMT, the cytoskeleton, and cancer cell invasion, Cancer and Metastasis Reviews, vol.20, issue.1, pp.15-33, 2009. ,
DOI : 10.1128/MCB.15.7.3805
N-Cadherin Is Regulated by Activin A and Associated with Tumor Aggressiveness in Esophageal Carcinoma, Clinical Cancer Research, vol.10, issue.17, pp.5702-5707, 2004. ,
DOI : 10.1158/1078-0432.CCR-03-0262
Activin A enhances MMP-7 activity via the transcription factor AP-1 in an esophageal squamous cell carcinoma cell line, International Journal of Oncology, vol.33, pp.453-459, 2008. ,
DOI : 10.3892/ijo_00000027
The Tryptophan-rich Motifs of the Thrombospondin Type 1 Repeats Bind VLAL Motifs in the Latent Transforming Growth Factor-?? Complex, Journal of Biological Chemistry, vol.264, issue.46, pp.47633-47642, 2004. ,
DOI : 10.2176/nmc.41.253
Cancer-associated fibroblasts induce epithelial???mesenchymal transition of breast cancer cells through paracrine TGF-?? signalling, British Journal of Cancer, vol.37, issue.3, pp.724-732, 2014. ,
DOI : 10.1016/j.canlet.2011.01.011
Two Faces of TGF-Beta1 in Breast Cancer, Mediators of Inflammation, vol.2, issue.2, 2014. ,
DOI : 10.1038/nchembio.500
The regulation of TGF-??/SMAD signaling by protein deubiquitination, Protein & Cell, vol.400, issue.5, pp.503-517, 2014. ,
DOI : 10.1038/23293
Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes, Breast Cancer Research, vol.19, issue.Suppl 1, p.52, 2011. ,
DOI : 10.1093/bioinformatics/btg345
URL : http://doi.org/10.1186/bcr2883
The p38 Mitogen-activated Protein Kinase Augments Nucleotide Excision Repair by Mediating DDB2 Degradation and Chromatin Relaxation, Journal of Biological Chemistry, vol.46, issue.47, pp.32553-32561, 2008. ,
DOI : 10.1073/pnas.96.2.424
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583317
DNA Damage-Binding Complex Recruits HDAC1 to Repress Bcl-2 Transcription in Human Ovarian Cancer Cells, Molecular Cancer Research, vol.12, issue.3, pp.370-380, 2014. ,
DOI : 10.1158/1541-7786.MCR-13-0281
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962721
DDB2 modulates TGF-?? signal transduction in human ovarian cancer cells by downregulating NEDD4L, Nucleic Acids Research, vol.43, issue.16, 2015. ,
DOI : 10.1093/nar/gkv667
Threonine 32 (Thr32) of FoxO3 is critical for TGF-??-induced apoptosis via Bim in hepatocarcinoma cells, Protein & Cell, vol.283, issue.2, pp.127-138, 2015. ,
DOI : 10.1074/jbc.M708083200
Transforming growth factor-?? signaling in tumor initiation, progression and therapy in breast cancer: an update, Cell and Tissue Research, vol.24, issue.Suppl 1, pp.73-84, 2012. ,
DOI : 10.1155/2008/747343
Role of Nuclear Factor-??B in Breast and Colorectal Cancer, Current Allergy and Asthma Reports, vol.42, issue.17, pp.44-49, 2013. ,
DOI : 10.1080/00365520600880856
Rôle de DDB2 dans l'adhérence des cellules tumorales mammaires: relation avec la voie du TGF?-1 ,
The transcriptional regulator DDB2 modulates TGF?1 signaling and membrane nanomechanics of breast cancer cells. CRCL Symposium, 21-23 Septembre 2015 ,
The Damaged DNA Binding 2 protein: a new modulator of TGF?1 signaling pathway and membrane nanomechanics in breast cancer cells.40 th FEBS Congress, p.36 ,
The Damaged DNA Binding 2 protein: a new modulator of TGF?-1 signaling pathway and membrane nanomechanics in breast cancer cells, 2015. ,
DDB2: un nouveau régulateur de la voie de signalisation du TGF?1? Conséquences sur les propriétés d'adhérence des cellules tumorales mammaires Journée de l'Ecole Doctorale BioSE, 25 Mars 2015 ,
The transcriptional regulator DDB2 modulates TGF?-1 signaling and cell adhesion in breast cancer cells. 8 ème Forum du Cancéropôle Grand-Est ,
URL : https://hal.archives-ouvertes.fr/hal-01100733
Role of DDB2 protein in breast cancer cells adhesion, 2014. ,