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Theses

Etude biomécanique de la distraction ostéogénique et de sa mise en oeuvre en chirurgie maxillofaciale

Abstract : Distraction osteogenesis is a process used to restore bone defects or to lengthen bone segments of the human body. It takes advantage of bone tissue ability to regenerate itself under an appropriate mechanical stimulation. The goal of this work is the optimisation of the ways this technique is implemented in maxillofacial surgery. A special focus has been done on the DEOS device from OBL company and on the associated protocols. In order to simulate mechanobiological changes happening in the distraction regenerate a micromechanical bone healing model was developed. After it was implemented in a computational routine, this approach was applied to a simplified bone distraction model. It allowed the numerical investigations of phenomena never simulated before. It also permitted to propose practical improvements of distraction protocols and devices. Moreover, the bone distraction force when using the DEOS was studied. An original method for the measurement of this force was set up taking into account restrictions of biomechanical tests. An experimental campaign was led with two patients benefiting from the DEOS. A database was then created and analysed. Finally, all the results obtained were used to optimise the DEOS up to clinicians and patients wishes. This has come to noticeable improvements of essential parameters as mass, size and practicality of this device
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Guillaume Dubois. Etude biomécanique de la distraction ostéogénique et de sa mise en oeuvre en chirurgie maxillofaciale. Médecine humaine et pathologie. Université Paul Verlaine - Metz, 2008. Français. ⟨NNT : 2008METZ023S⟩. ⟨tel-01752591⟩

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