A. Et-un, Mécanisme de la réaction de Staudinger entre une phosphine tertiaire, Schéma, vol.29

.. De-staudinger, Voie de synthèse des dérivés phosphorés pour la ligation, Schéma, vol.31

. Synthèse-du-dérivé-de-fluorescéine-selon-chen, Metabolism and Function, Schéma Ann. Rev. Biochem, vol.38, issue.52, pp.1-15, 1976.

Y. Li, G. Wei, and . Chen, Glutathione: a review on biotechnological production, Applied Microbiology and Biotechnology, vol.134, issue.3, pp.233-242, 2004.
DOI : 10.1271/bbb1961.50.1361

C. Hwang, A. J. Sinskey, and . H. Lodish, Oxidized redox state of glutathione in the endoplasmic reticulum, Science, vol.257, issue.5076, pp.1496-1502, 1992.
DOI : 10.1126/science.1523409

. Dans-ce-manuscrit, nous employons le terme général de "benzophénone" à la place de "diphényl méthanone

. Pour-notre-Étude, nous avons choisi d'utiliser la méthode standard d'acylation 58 (en présence d'un acide de Lewis) car les réactifs nécessaires sont accessibles dans le commerce

K. Ogura, D. Tetrahedron-lett-wang, Z. Zhang, C. Zhou, R. C. Larock et al., A. Friedel-Crafts Chemistry Ed, Org. Lett. J. Am. Chem. Soc. Tetrahedron Lett. J. Org. Chem, vol.44, issue.56, pp.271-273, 1973.
URL : https://hal.archives-ouvertes.fr/hal-00002585

B. W. Hotten, Metal Terephthalamates, Industrial & Engineering Chemistry, vol.49, issue.10, pp.1691-1694, 1957.
DOI : 10.1021/ie50574a026

C. S. 62-rondestvedt and . Jr, Aminations with ammonia and formamide. Synthesis of terephthalamic acid and of p-nitroaniline, The Journal of Organic Chemistry, vol.42, issue.19, pp.3118-3123, 1977.
DOI : 10.1021/jo00439a003

S. Tam, L. Jimenez, F. Diederich, V. Dufaud, J. Thivolle-cazat et al., One pot synthesis of aromatic methyl esters by electrochemical oxidation of aldehydes mediated by biscoenzyme catalysis, Journal of the American Chemical Society, vol.114, issue.4, pp.1503-1505, 1990.
DOI : 10.1021/ja00030a069

M. Giurg, S. B. Said, L. Syper, and . Mlochowski, ONE-POT OXIDATION OF AZOMETHINE COMPOUNDS INTO ARENECARBOXYLIC ACIDS, Synthetic Communications, vol.71, issue.20, pp.3151-3159, 2001.
DOI : 10.1007/978-1-4684-4313-4

.. Formation-du-motif-benzophénone, Méthylphényl)(phényl)méthanone ou 4-méthylbenzophénone (1), p.67

C. Grandjean, A. Boutonnier, C. Guerreiro, J. Fournier, and L. A. Mulard, On the Preparation of Carbohydrate???Protein Conjugates Using the Traceless Staudinger Ligation, The Journal of Organic Chemistry, vol.70, issue.18, pp.7123-7132, 2005.
DOI : 10.1021/jo0505472

M. B. Soellner, B. L. Nillson, R. T. Raines, E. Saxon, S. J. Luchansky et al., Reaction Mechanism and Kinetics of the Traceless Staudinger Ligation, Journal of the American Chemical Society, vol.128, issue.27, pp.8820-8828, 2002.
DOI : 10.1021/ja060484k

B. L. Nilsson, R. J. Hondal, M. B. Soellner, and R. T. Raines, Protein Assembly by Orthogonal Chemical Ligation Methods, Journal of the American Chemical Society, vol.125, issue.18, pp.5268-5269, 2003.
DOI : 10.1021/ja029752e

C. Manolov, I. Danchev, N. D. Manohar, D. Kulkarni, V. Shobha et al., (b) Manolov, I.; Maichle-Moessmer, C.; Danchev, N. Eur, Eur. J. Med. Chem. J. Me J. Med. Chem. Eur. J. Med. Chem. Eur. J. Med. Chem, vol.40, issue.40, pp.1168-1172, 1970.

L. Couplage-À, Diphénylphosphino)phényl5-(2-oxohexahydro-1H-thiéno[3,4-d]imidazol-4-yl) pentanoate (33), pp.2-234

.. Synthèse-de-la-biotine-modifiée, 235 1-{[5-(2-Oxohexahydro-1H-thiéno[3,4-d]imidazol-4-yl)pentanoyl]oxy}-2,5- pyrrolidinedione (34)d]imidazol-4-yl)-N-(2-propynyl)pentanamide (35), p.236

.. Essais-avec-une-molécule-test, -(4-Benzoylbenzyl)-1H-1,2,3-triazol-4-yl]méthyl}-5-(2-oxohexahydro-1H- thiéno[3,4-d]imidazol-4-yl)pentanamide (36), p.237

R. De, C. Chemistry-sur-les-molécules-bifonctionnelles, and .. , 241 7-{[1-(4-Benzoylbenzyl)-1H-1,2,3-triazol-4-yl]méthoxy}-4-méthyl-2H-chromen-2-one (45a)triazol-4-yl}méthoxy)-4-méthyl-2H- chromen-2-one (45b), p.242

.. Essais-avec-une-structure-trifonctionnelle, )oxy]méthyl}-1H-1,2,3-triazol-1- yl)méthyl]benzoyl}benzoyl)oxy]-2,5-pyrrolidinedione (49), ., vol.253, pp.1-4

F. G. Hopkins, On an Autoxidisable Constituent of the Cell, Biochemical Journal, vol.15, issue.2, pp.286-305, 1921.
DOI : 10.1042/bj0150286

E. M. Kosower, M. A. Arias, and W. B. Jakoby, Metabolism and Function, pp.1-15, 1976.

C. Hwang, A. J. Sinskey, and . H. Lodish, Oxidized redox state of glutathione in the endoplasmic reticulum, Science, vol.257, issue.5076, pp.1496-1502, 1992.
DOI : 10.1126/science.1523409

G. E. Arteel and H. Sies, The biochemistry of selenium and the glutathione system, Environmental Toxicology and Pharmacology, vol.10, issue.4, pp.153-158, 2001.
DOI : 10.1016/S1382-6689(01)00078-3

R. Dringer, J. M. Gutterer, J. Hirrlingen, and R. Dringer, Glutathione metabolism in brain, European Journal of Biochemistry, vol.73, issue.16, pp.4912-4916, 2000.
DOI : 10.1046/j.1471-4159.1999.731683.x

J. Koolman and K. Röhm, Atlas de poche de Biochimie, 3 ème Ed, p.284, 2004.

F. Q. Schafer and G. R. Buttner, Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple, Free Radical Biology and Medicine, vol.30, issue.11, pp.1191-1212, 2001.
DOI : 10.1016/S0891-5849(01)00480-4

I. Rahman and W. Macnee, Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease, American Journal of Physiology-Lung Cellular and Molecular Physiology, vol.55, issue.18, pp.1067-1088, 1999.
DOI : 10.1016/0891-5849(94)00236-D

G. K. Balendiran, R. Dabur, and D. Fraser, The role of glutathione in cancer, Cell Biochemistry and Function, vol.89, issue.112, pp.343-352, 2004.
DOI : 10.1007/978-3-642-67132-6_20

L. F. Chasseaud, M. A. Glutathione-arias, W. B. Jakoby, and O. W. Griffith, Metabolism and Function, Free Radical Biol. Med, vol.27, pp.77-114, 1976.

D. A. Butterfield, C. B. Pocernich, and J. Drake, Elevated glutathione as a therapeutic strategy in Alzheimer's disease, Drug Development Research, vol.62, issue.3, pp.428-437, 2002.
DOI : 10.1271/bbb.62.710

A. G. Hall and . Eur, The role of glutathione in the regulation of apoptosis, European Journal of Clinical Investigation, vol.47, issue.1, pp.238-245, 1999.
DOI : 10.1016/0959-8049(96)00051-2

A. Celli, F. G. Que, G. J. Gores, and N. F. Larusso, Glutathione depletion is associated with decreased Bcl-2 expression and increased apoptosis in cholangiocytes, American Journal of Physiology-Gastrointestinal and Liver Physiology, vol.81, issue.41, pp.749-757, 1998.
DOI : 10.1016/S0039-6060(96)80282-0

E. L. Vodovozova, Photoaffinity labeling and its application in structural biology, Biochemistry (Moscow), vol.6, issue.1, pp.1-20, 2007.
DOI : 10.1042/bj3280489

S. A. Fleming, Chemical reagents in photoaffinity labeling, Tetrahedron, vol.51, issue.46, pp.12479-12520, 1995.
DOI : 10.1016/0040-4020(95)00598-3

H. Bayley and J. R. Knowles, [8] Photoaffinity labeling, Methods Enzymol, vol.46, pp.69-114, 1977.
DOI : 10.1016/S0076-6879(77)46012-9

R. A. Smith and J. R. Knowles, Aryldiazirines. Potential reagents for photolabeling of biological receptor sites, Journal of the American Chemical Society, vol.95, issue.15, pp.5072-5073, 1973.
DOI : 10.1021/ja00796a062

G. Dorman and G. Prestwich, Benzophenone Photophores in Biochemistry, Biochemistry, vol.33, issue.19, pp.5661-5673, 1994.
DOI : 10.1021/bi00185a001

G. Dorman, J. D. Olszewski, and G. D. Prestwich, Synthesis of Highly Tritiated 4-Benzoyl-L-phenylalanine, a Photoactivatable Amino Acid, The Journal of Organic Chemistry, vol.60, issue.7, pp.2292-2297, 1995.
DOI : 10.1021/jo00112a066

P. E. Dawson, T. W. Muir, I. Clark-lewis, and S. B. Kent, Synthesis of proteins by native chemical ligation, Science, vol.266, issue.5186, pp.776-779, 1994.
DOI : 10.1126/science.7973629

H. C. Kolb, M. G. Finn, and K. B. Sharples, Click Chemistry: Diverse Chemical Function from a Few Good Reactions, Angewandte Chemie International Edition, vol.36, issue.6, pp.2004-2021, 2001.
DOI : 10.1016/B978-008096518-5.00095-2

T. W. Green, P. G. Wuts, S. Bräse, C. Gil, K. Knepper et al., Protective groups in Organic Synthesis 2 nd Ed, Angew. Chem. Int. Ed. Chem. Rev, vol.69, issue.52, pp.5188-5240, 1969.

S. Paul, P. Nanda, R. Gupta, A. Loupy, M. H. Sarvari et al., Synthesis Te 54 Friedel-Crafts Chemistry Ed, P. DE Patent 2, pp.2877-2881, 1240.

E. Campaigne, (b) Katritzky, th, J. Org. Chem, vol.65, issue.5, pp.5834-5836, 1963.

. Commun, A.; Morera, I.M.; Pérez-Prieto, J.; Sarabia, Z. Photochem. Photobiol, vol.68, pp.2244-2245, 1998.
URL : https://hal.archives-ouvertes.fr/hal-01210602

M. Gopalkrishnan, P. Sureshkumar, V. Kanagarajan, J. Thanusu, P. A. Janssen et al., Catalysis Commun, P.; Boey, J.M. U Chem. Abst, vol.6, issue.87, pp.753-756, 1977.

C. S. Rondestvedt and . Jr, Aminations with ammonia and formamide. Synthesis of terephthalamic acid and of p-nitroaniline, The Journal of Organic Chemistry, vol.42, issue.19, pp.3118-3123, 1977.
DOI : 10.1021/jo00439a003

K. S. Webb, S. J. Ruszkay, B. R. Travis, M. Sivakumar, G. Hollist et al., Oxidation of aldehydes with Oxone?? in aqueous acetone, Tetrahedron, vol.54, issue.3-4, pp.401-410, 1979.
DOI : 10.1016/S0040-4020(97)10299-X

S. Tam, L. Jimenez, F. Diederich, G. W. Ebert, W. L. Juda et al., One pot synthesis of aromatic methyl esters by electrochemical oxidation of aldehydes mediated by biscoenzyme catalysis, Journal of the American Chemical Society, vol.114, issue.4, pp.1503-1505, 1992.
DOI : 10.1021/ja00030a069

M. T. Bogert and C. L. Harris, THE SYNTHESIS OF SOME HOMOLOGS OF THE TERPENES, DERIVATIVES OF 1,4-DIISOPROPYL CYCLOHEXANE., Journal of the American Chemical Society, vol.41, issue.10, pp.1676-1690, 1919.
DOI : 10.1021/ja02231a017

J. Zhu, X. Wang, Y. Chen, X. Jiang, X. Chen et al., Hydrogen-Bonding-Induced Planar, Rigid, and Zigzag Oligoanthranilamides. Synthesis, Characterization, and Self-Assembly of a Metallocyclophane, The Journal of Organic Chemistry, vol.69, issue.19, pp.6221-6227, 2004.
DOI : 10.1021/jo0490705

M. Reimer and H. R. Downes, THE PREPARATION OF ESTERS BY DIRECT REPLACEMENT OF ALKOXYL GROUPS., Journal of the American Chemical Society, vol.43, issue.4, pp.945-951, 1921.
DOI : 10.1021/ja01437a032

J. L. Williams, T. M. Laakso, K. R. Dunham, D. G. Borden, J. A. Vanderberghe-vanallan et al., Bisesteramides of Terephthalic Acid, The Journal of Organic Chemistry, vol.25, issue.5, pp.817-820, 1960.
DOI : 10.1021/jo01075a039

E. Chenot, D. Bernardi, A. Comel, and G. Kirsch, Preparation of Monoalkyl Terephthalates: An Overview, Synthetic Communications, vol.37, issue.3, pp.483-490, 2004.
DOI : 10.1039/c39900000426

A. R. Katritzky, X. Lan, J. Z. Yang, and O. V. Denisko, -Substituted Benzotriazoles, Chemical Reviews, vol.98, issue.2, pp.409-548, 1998.
DOI : 10.1021/cr941170v

J. F. Mcomie, M. L. Watts, and D. E. West, Demethylation of aryl methyl ethers by boron tribromide, Tetrahedron, vol.24, issue.5, pp.2289-2292, 1968.
DOI : 10.1016/0040-4020(68)88130-X

J. R. Pollock and R. Stevens, Dictionary of Organic Compounds, p.2949, 1965.

D. Bernardi, Synthèse d'analogues photoactivables du glutathion pour l'étude du système cellulaire du glutathion, Thèse soutenue le 19 octobre 2005

F. Rouessac, A. Rouessac, D. Cruché, D. J. Harrison, and L. G. Hameetman, Analyse chimique : méthodes et techniques, Gut J.H, vol.32, issue.249, pp.1546-1549, 1974.

S. J. Earce, . Org, . Lett-tetrahedron, and . Lett, (c) Grieco, onterrey, I, Synlett, vol.207, issue.30, pp.329-332, 1982.

J. H. Birkinshaw and P. Chaplen, Murr, Biochemical Journal, vol.60, issue.2, pp.255-259, 1955.
DOI : 10.1042/bj0600255

J. M. Griffing and L. F. Salisbury, 2,5-bis-(Chloromethyl)-thiophene and Some of its Derivatives, Journal of the American Chemical Society, vol.70, issue.10, pp.3416-3419, 1948.
DOI : 10.1021/ja01190a056

R. C. Larock, Comprehensive Organic Transformation. A guid to functional Group Preparation, p.409, 1989.

H. Ryu, M. Jin, S. Y. Kim, H. Choi, S. Kang et al., -(2-Benzyl-3-pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide Analogues, Journal of Medicinal Chemistry, vol.51, issue.1, pp.57-67, 2008.
DOI : 10.1021/jm701049p

S. Díaz, A. González, . S. González-de-riancho, and A. Rodríguez, Boron complexes of S-trityl-l-cysteine and S-tritylglutathione, Journal of Organometallic Chemistry, vol.610, issue.1-2, pp.25-30, 2000.
DOI : 10.1016/S0022-328X(00)00363-6

R. J. Cook, R. Björnestedt, K. T. Douglas, J. H. Mckie, M. D. King et al., Photoaffinity labelling of the active site of the rat glutathione transferases 3-3 and 1-1 and human glutathione transferase A1-1, Biochemical Journal, vol.302, issue.2, pp.383-390, 1994.
DOI : 10.1042/bj3020383

H. Albert, Triphényl S-glutathion : Evaluation in vitro et effet sur la résistance de cellu Master soutenu le 26 juin, 2007.

C. Thiele and F. Fahrenholz, Photoaffinity labeling of central cholecystokinin receptors with high efficiency, Biochemistry, vol.32, issue.11, pp.2741-2746, 1993.
DOI : 10.1021/bi00062a002

E. H. White, O. Zafiriou, H. H. Kägi, and J. H. Hill, Chemilunimescence of Luminol: The Chemcial Reaction, Journal of the American Chemical Society, vol.86, issue.5, pp.940-941, 1964.
DOI : 10.1021/ja01059a050

R. Mülhaupt, Hermann Staudinger and the Origin of Macromolecular Chemistry, Angewandte Chemie International Edition, vol.43, issue.9, pp.1054-1063, 2004.
DOI : 10.1002/anie.200330070

H. Ringsdorf, Hermann Staudinger and the Future of Polymer Research Jubilees???Beloved Occasions for Cultural Piety, Angewandte Chemie International Edition, vol.43, issue.9, pp.1064-1076, 2004.
DOI : 10.1002/anie.200330071

H. Staudinger and J. Meyer, ??ber neue organische Phosphorverbindungen III. Phosphinmethylenderivate und Phosphinimine, Helvetica Chimica Acta, vol.2, issue.1, pp.635-646, 1919.
DOI : 10.1002/hlca.19190020164

F. L. Lin, H. M. Hoyt, H. Van-halbeck, R. G. Bergman, and C. R. Bertozzi, Mechanistic Investigation of the Staudinger Ligation, Journal of the American Chemical Society, vol.127, issue.8, pp.2686-2695, 2005.
DOI : 10.1021/ja044461m

E. Saxon, J. I. Armstrong, and C. R. Bertozzi, A ???Traceless??? Staudinger Ligation for the Chemoselective Synthesis of Amide Bonds, Organic Letters, vol.2, issue.14, pp.2141-2143, 2000.
DOI : 10.1021/ol006054v

C. Grandjean, A. Boutonnier, C. Guerreiro, J. Fournier, . Mulard et al., Soel 133, Tetrahedron: Asymmetry J. Am. Chem. Soc, vol.70, issue.125, pp.7123-7132, 2002.

M. Azoulay, G. Tuffin, W. Sallem, and J. C. Florent, A new drug-release method using the Staudinger ligation, Bioorganic & Medicinal Chemistry Letters, vol.16, issue.12, pp.3147-3149, 2006.
DOI : 10.1016/j.bmcl.2006.03.073

R. Merkx, D. T. Rijkers, J. Kemmink, R. M. Liskamp, B. L. Nilsson et al., Chemoselective coupling of peptide fragments using the Staudinger ligation, Tetrahedron Letters, vol.44, issue.24, pp.4515-4518, 2003.
DOI : 10.1016/S0040-4039(03)01014-1

M. Tsao, F. Jian, P. G. Schultz, E. Block, V. Eswarakrishnan et al., Figul 141, J. Am. Chem. Soc. J. J. Am. Chem. Soc, vol.6, issue.111, pp.2147-2149, 1989.

T. B. Rauchfuss, o-Diphenylphosphinophenol and its coordination compounds, Inorganic Chemistry, vol.16, issue.11, pp.2966-2968, 1977.
DOI : 10.1021/ic50177a062

D. B. Grotjahn, C. Joubran, and D. Combs, Controlled oxidative addition of amino acid esters to Rh(I), Journal of Organometallic Chemistry, vol.589, issue.1, pp.115-121, 1999.
DOI : 10.1016/S0022-328X(99)00311-3

R. Huisgen, 1,3-Dipolar cycloaddition chemistry, pp.1-176, 1984.

J. Lutz, 1,3-Dipolar Cycloadditions of Azides and Alkynes: A Universal Ligation Tool in Polymer and Materials Science, Angewandte Chemie International Edition, vol.45, issue.7, pp.1018-1025, 2007.
DOI : 10.1002/anie.200604050

V. V. Rostovsev, L. G. Green, V. V. Fokin, and K. B. Sharpless, A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective ???Ligation??? of Azides and Terminal Alkynes, Angewandte Chemie International Edition, vol.20, issue.14, pp.2596-2599, 2002.
DOI : 10.1002/1099-0682(200011)2000:11<2311::AID-EJIC2311>3.0.CO;2-7

M. Whiting, J. Muldoon, Y. Lin, S. M. Silverman, W. Lindostrom et al., Inhibitors of HIV-1 Protease by Using In Situ Click Chemistry, Angewandte Chemie International Edition, vol.67, issue.9, pp.1435-1439, 2006.
DOI : 10.1002/1521-3773(20020315)41:6<1053::AID-ANIE1053>3.0.CO;2-4

F. Himo, T. Lovell, R. Hilgraf, V. V. Rostovtsev, and V. V. Noo-fokin, Copper(I)-Catalyzed Synthesis of Azoles. DFT Study Predicts Unprecedented Reactivity and Intermediates, Journal of the American Chemical Society, vol.127, issue.1, pp.210-216, 2005.
DOI : 10.1021/ja0471525

Q. Wang, T. R. Chan, R. Hilgraf, V. V. Fokin, K. B. Sharpless et al., Bioconjugation by Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition, Journal of the American Chemical Society, vol.125, issue.11, pp.3192-3193, 2003.
DOI : 10.1021/ja021381e

V. O. Rodionov, S. I. Presolski, S. Gardinier, Y. Lim, and M. G. Finn, Benzimidazole and Related Ligands for Cu-Catalyzed Azide???Alkyne Cycloaddition, Journal of the American Chemical Society, vol.129, issue.42, pp.12696-12704, 2007.
DOI : 10.1021/ja072678l

N. J. Agard, J. A. Prescher, C. R. Bertozzi, T. Hsu, S. R. Hanson et al., A Strain-Promoted [3 + 2] Azide???Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems, probes and labeling technologies, pp.15046-15047, 2004.
DOI : 10.1021/ja044996f

D. Arosio, M. Bertoli, L. Manzonib, and C. Scolasticoa, Click chemistry to functionalise peptidomimetics, Tetrahedron Letters, vol.47, issue.22, pp.3697-3700, 2006.
DOI : 10.1016/j.tetlet.2006.03.149

H. C. Kolb, J. C. Walsh, K. Chen, and J. Lutz, (b) Sir Tetrahedron Lett, XO2006116629, Chem. Abst, vol.145, issue.60, pp.455222-3953, 2006.

P. Lin, S. Ueng, S. Yu, M. Jan, A. K. Adak et al., Surface Modification of Magnetic Nanoparticle via Cu(I)-Catalyzed Alkyne-azide [2 + 3] Cycloaddition, Organic Letters, vol.9, issue.11, pp.2131-2134, 2007.
DOI : 10.1021/ol070588f

R. Hayland, The Handbook : A guide to fluorescent 10 th Ed. Molecular Probes Invitrogen, 2005.

I. Kosiova, S. Kovackova, P. Kois, . Nonaka, S. Tsukiji et al., Synthesis of coumarin???nucleoside conjugates via Huisgen 1,3-dipolar cycloaddition, Tetrahedron, vol.63, issue.2, pp.312-320, 2007.
DOI : 10.1016/j.tet.2006.10.075

I. Kosiova and P. Kois, Synthesis of novel coumarin based fluorescent probes 10 th International Electronic Conference on Synthetic Organic Chemistry

R. Berscheid, M. Nieger, and F. Vögtle, Konkave Farbstoffmolek??le vom Triphenylmethan-Typ, Chemische Berichte, vol.112, issue.11, pp.2539-2552, 1992.
DOI : 10.5059/yukigoseikyokaishi.46.96

X. Z. Zhao, E. A. Semenova, and C. Liao, Biotinylated biphenyl ketone-containing 2,4-dioxobutanoic acids designed as HIV-1 integrase photoaffinity ligands, Bioorganic & Medicinal Chemistry, vol.14, issue.23, pp.7816-7825, 2006.
DOI : 10.1016/j.bmc.2006.07.064

J. P. Badyal, A. M. Cameron, N. R. Cameron, D. M. Coe, R. Cox et al., A simple method for the quantitative analysis of resin bound thiol groups, Tetrahedron Letters, vol.42, issue.48, pp.8531-8533, 2001.
DOI : 10.1016/S0040-4039(01)01820-2

4. Terephthalic, C. Ar, and . Nmr, CDCl 3 ): 1.41 (t, J ¼ 7.1 Hz, 6H, -O-CH 2 -CH 3 ), 4.41 (q, J ¼ 7.1 Hz, 4H, -O-CH 2 -CH 3, p.61

4. Terephthalic and . Ar, CDCl 3 ): 1.04 (t, J ¼ 7.3 Hz, 6H, -O-CH 2 -CH 2 -CH 3 ), 1.81 (m, 4H, -O-CH 2 -CH 2 -CH 3, C NMR (CDCl, vol.8, issue.1294

. Terephthalic, 1. Ester, and 4. Ar, CDCl 3 ): 1.39 [d, J ¼ 6, C NMR (CDCl 3 ): 21.9 (-O-CH-(CH 3 ) 2 )

. Terephthalic and . Ester, CDCl 3 ): 0.99 (t, J ¼ 7.3 Hz, 6H, -O-CH 2 -CH 2 -CH 2 -CH 3 ), 1.48 (m, 4H, -O-CH 2 -CH 2 -CH 2 -CH 3, 4H, -O-CH 2 -CH 2 -CH 2 -CH 3 Hz, 4H, -O-CH 2 -CH 2 - CH 2 -CH 3 ), pp.77-90

5. Ei, 1 (-O-CH 2 -CH 2 -CH 2 -CH 3, CH 2 -CH 2 -CH 2 -CH 3 ), pp.278-223

D. Monomethyl-esterm and 4. Ar, CDCl 3 ): 3.76 (s, 3H, C Ar ), vol.7, issue.1661, pp.165-165

,. Monoisopropyl-ester and H. Ar, CDCl 3 ): 1.00 [d, J ¼ 6.1 Hz, 6H, -O- CH-(CH 3 ) 2 ], 4.85 [sep

C. Nmr, 21.7 [-O-CH-(CH 3 ) 2 ], 68, C Ar ), vol.2, issue.1671, pp.5-5

2. Monobutyl-esterm, Highly selective monomethyl esterification of terephthalic acid by use of monocarboxylate chemisorption on alumina Selective monomethyl esterification of dicarboxylic acids by use of monocarboxylate chemisorption on alumina, -CH 2 -CH 2 -CH 2 -CH 3 ), 1.38 (m, 2H, -O- CH 2 -CH 2 -CH 2 -CH 3 Tertani, S.; Taya, K. Methylation of alcohols, phenols and carboxylic acids and selective monomethylation of diols and dicarboxylic acids with dimethyl sulphate by use of alumina, pp.0-59, 1980.

M. Saitoh, S. Fujisaki, Y. Ishii, and T. Nishiguchi, Convenient selective monoesterification of ??, ??-dicarboxylic acids catalyzed by ion-exchange resins, Tetrahedron Letters, vol.37, issue.37, pp.6733-6736, 1996.
DOI : 10.1016/S0040-4039(96)01454-2

N. W. Boaz, M. E. Martin, D. Planchenault, and F. Huet, Enzymatic desymmetrization of cis-1,3-cyclohexanedicarboxylic acid diesters, Tetrahedron: Asymmetry, vol.10, issue.5, pp.813-816, 1995.
DOI : 10.1016/S0957-4166(99)00060-9

T. Hasegawa and H. Yamamoto, A Selective Partial Hydrolysis of Dimenthyl Ester Using Dry Tetrabutylammonium Hydroxide, Synlett, vol.1999, issue.1, pp.84-86, 1999.
DOI : 10.1055/s-1999-2529

B. W. Hotten, C. S. Rondestvedt, . Jr, and D. G. Borden, Metal Terephthalamates, Industrial & Engineering Chemistry, vol.49, issue.10, pp.1691-1694, 1957.
DOI : 10.1021/ie50574a026

J. Vanderberghe, J. A. Vanallan, and D. D. Reynolds, Bisesteramides of terephthalic acid, J. Org. Chem, vol.25, pp.817-820, 1960.

S. Niwayama, R. Ballini, and G. Bosica, Highly Efficient Selective Monohydrolysis of Symmetric Diesters, The Journal of Organic Chemistry, vol.65, issue.18, pp.5834-5836, 2000.
DOI : 10.1021/jo0001986

M. Petrini and C. Pierantozzi, Conjugate addition of nitroalkanes to dimethyl maleate: Regioselective formation of both monoesters of 2-alkylsuccinic acids, Tetrahedron, vol.59, pp.7283-7289, 2003.

S. W. Tam, L. Jimenez, F. Diederich, and K. S. Webb, One pot synthesis of aromatic methyl esters by electrochemical oxidation of aldehydes mediated by biscoenzyme catalysis, Journal of the American Chemical Society, vol.114, issue.4, pp.1503-1505, 1992.
DOI : 10.1021/ja00030a069

S. J. Ruszkay, S. K. Sharma, M. Tandon, J. W. Lown, and K. Yasuda, Oxidation of aldehydes with oxone in aqueous acetone Synthesis of geometrically constrained unsymmetrical bis(polyamides) related to the antiviral distamycin, Tetrahedron Eur. J. Org. Chem, pp.401-410, 1998.

S. V. Ley and B. Travis, Solid-supported reagents for the oxidation of aldehydes to carboxylic acids, Synlett, pp.1555-1556, 2001.

G. O. Hollist and B. Borhan, Facile oxidation of aldehydes to acids and esters with oxone, Org. Lett, vol.5, pp.1031-1034, 2003.

J. R. Pollock and R. Stevens, Dictionary of Organic Compounds, p.2949, 1965.

. Da and . Gc, Packard 5971A electron impact (70eV) mass spectrometer, equipped with a Hewlett Packard 5890 series II gas chromatograph. 1 H and 13 C nmr spectra were recorded on a Bruker-AC 250-M Hz spectrometer with CDCl 3 or DMSO-d 6 as both solvent and internal reference. The chemical shifts () are expressed in ppm and coupling constants (J) in Hz. Compounds 1-3 were prepared as described in the literature, -Oxo-2H-benzo[h]chromen-4-yl)-acetic acid

. Hz, (2-Oxo-2H-benzo[h]chromen-4-yl)-N-(2-propyn-yl)- acetamide (8) To a solution of (2-oxo-2H-benzo[h]- chromen-4-yl)acetic acid (1 g, 3.93 mmol) in dry dimethylformamide (5 mL) were added N-hydroxysuccinimide (0.476 g, 4.13 mmol) and N,N'-dicyclohexylcarbodiimide (1.7 g, 8.28 mmol) in dimethylformamide (5 mL) The mixture was stirred at room temperature for 24 h, then propargylamine (0.276 mL, 4.02 mmol) was added and left to stir overnight at the same temperature. The formed precipitate was filtered. The obtained filtrate was poured into water, filtrated, washed with water and dried at room temperature until constant weight. Pure product was obtained by cristallisation from diethyl ether. (0.65 g), 57 %, dark beige solid General procedure for the preparation of compounds 9 (ad ) The mixture was refluxed for 4 h, 1H, NH, J=5.3 Hz), 8.38-8.34 (m, 1H), 8.05-8.00 (m, 1H), 7.84 (d, 1H, J=8.7 Hz) Thionyl chloride excess was evaporated in vacuo. To the obtained acid chloride was added toluene (2.13 mL mL), and aluminium chloride, pp.20-22

. Hz, 21 (s, 4H42 (s, 3H, CH 3 ) 13 C nmr (CDCl 3 ): 187, J=7.8, 2.3 Hz), 5.91 (d, 1H, J=1.2 Hz), 5.66 (s, 2H, NCH 2 ), 5.65 (s, 2H, NCH 2 ), pp.62-69

1. Hzd and J. , 31 (s, 2H16 (s, 2H33 (s, 3H, CH 3 ) 13 C nmr (DMSO-d 6 ): 177 General procedure for the preparation of compounds 15 (a-d) Compounds 15a-d were obtained from 2-(2-Oxo-2H- benzo[h]chromen-4-yl)-N-(2-propyn-yl)acetamide 8, using the same procedure as for 12a-d. N-{[1-(4-Benzoylbenzyl)-1H-1, 2H, J=3.9, 1.1 Hz) (t, 1H, NH, J=5.3 Hz), pp.93-100

. Hz, 86 (s, 2H, COCH 2 ) 13 C nmr (DMSO-d 6 ): 195.2, 167, thienyl)methyl]-1H-1, pp.5568-5572

1. , N. , J. Huisgen, and R. , -thienyl- carbonyl)benzyl]-1H-1,2,3-triazol-4-yl}methyl)acetamide (15c) (0.52 g), 97 %, pale yellow solid, mp 196-199 °C. 1 H nmr55 (s, 1H), 5.68 (s, 2H86 (s, 2H, COCH 2 ) 13 C nmr (DMSO-d 6 ): 186(2-thienyl- carbonyl)-2-thienyl]methyl}-1H-1,2,3-triazol-4-yl)methyl]- acetamide (15d), 3 Hz), 8.37-8.33 (m, 1H), 8.12 (dd, 1H, J=4.9, 0.8 Hz) 8.02-7.98 (m, 2H), 7.81-7.67 (m, 7H), 7.41 (d, 2H, J=8.1 Hz), 7.27 (dd, 1H, J=4.8, 3.9 Hz) 1H, J=3.8 Hz), 6.55 (s, 1H), 5.859 (s, 2H, NCH 2 )a) Huisgen, R. 1,3-Dipolar Cycloaddition Chemistry Pawda, pp.8-81, 1963.

V. Kanagarajan, J. Thanusu, O. Kang, J. Luo, Y. Bai et al., Catalysis Commun, J. Organomet. Chem. Tetrahedron Lett, vol.690, issue.46, pp.6309-7627, 2005.