A. T. Abdelhafeez, H. Harssema, G. Veri, and K. Vekerk, Effects of soil and air temperature on growth, development and water use of tomatoes, Neth. J. Agric. Sci, vol.19, issue.6, pp.67-75, 1971.

F. Afreen, S. M. Zobayed, and T. Kozai, Spectral quality and??UV-B stress stimulate glycyrrhizin concentration of??Glycyrrhiza??uralensis in??hydroponic and??pot system, Plant Physiology and Biochemistry, vol.43, issue.12, pp.1074-1081, 2005.
DOI : 10.1016/j.plaphy.2005.11.005

G. K. Agrawal, N. S. Jwa, H. Iwahashi, and R. Rakwal, Importance of ascorbate peroxidases OsAPX1 and OsAPX2 in the rice pathogen response pathways and growth and reproduction revealed by their transcriptional profiling, Gene, vol.322, pp.93-103, 2003.
DOI : 10.1016/j.gene.2003.08.017

A. Balkhi and M. H. , Etude du métabolisme des alcaloïdes tropaniques dans les racines trangéniques de Datura innoxia: Identification par LC-MS et isolement par HPLC prépaative de composés intermédiaires et dérivés, p.24, 2004.

A. Angersbach, V. Heinz, and D. Et-knorr, Effects of pulsed electric fields on cell membranes in real food systems, Innovative Food Science & Emerging Technologies, vol.1, issue.2, pp.135-149, 2000.
DOI : 10.1016/S1466-8564(00)00010-2

T. Aoki, H. Matsumoto, Y. Asako, Y. Matsumaga, and K. Shimomura, Variation of alkaloid productivity among several clones of hairy roots and regenerated plants of Atropa belladonna transformed with Agrobacterium rhizogenes 15834, Plant Cell Reports, vol.16, issue.5, pp.282-286, 1997.
DOI : 10.1007/s002990050223

H. P. Bais, S. W. Park, T. L. Weir, R. M. Callaway, and J. M. Vivanco, How plants communicate using the underground information superhighway, Trends in Plant Science, vol.9, issue.1, pp.26-32, 2004.
DOI : 10.1016/j.tplants.2003.11.008

H. P. Bais, V. M. Loyola-vargas, H. E. Flores, and J. M. Vivanco, Root-specific metabolism: The biology and biochemistry of underground organs, In Vitro Cellular & Developmental Biology - Plant, vol.121, issue.6, pp.730-741, 2001.
DOI : 10.1007/978-3-642-78130-8

Y. P. Bajaj, Biotechnology in agriculture and forestry 45, transgenic medicinal plants, p.372, 1999.

R. Baranski, E. Klocke, and G. Schumann, Green fluorescent protein as an efficient selection marker for Agrobacterium rhizogenes mediated carrot transformation, Plant Cell Reports, vol.78, issue.3, pp.190-197, 2006.
DOI : 10.1099/00221287-98-2-477

J. M. Baskin, C. J. Ludlow, T. M. Harris, and F. T. Wolf, Psoralen, an inhibitor in the seeds of Psoralea subacaulis (Leguminosae), Phytochemistry, vol.6, issue.9, pp.1209-1213, 1967.
DOI : 10.1016/S0031-9422(00)86083-5

R. G. Birch, PLANT TRANSFORMATION: Problems and Strategies for Practical Application, Annual Review of Plant Physiology and Plant Molecular Biology, vol.48, issue.1, pp.297-326, 1997.
DOI : 10.1146/annurev.arplant.48.1.297

M. Boitel-conti, J. C. Laberche, E. Gontier, and B. S. Sangwan-norrel, Inducer effect of Tween 20 permeabilization treatment used for release of stored tropane alkaloids in Datura innoxia Mill. hairy root cultures, Plant Cell Reports, vol.16, issue.3-4, pp.241-244, 1996.
DOI : 10.1007/s002990050215

M. Boitel, E. Gontier, C. Assaf, J. C. Laberche, and B. S. Et-sangwan, Procédé de production de métabolites primaires et secondaires à partir d'organes végétaux cultivés in vitro, 1997.

V. L. Bonhomme, Transformation génétique de plantes médicinales : Atropa belladonna et Papaver somniferum Var. Album par les gènes rol impact sur le métabolisme alcaloïdique, Thèse de doctorat, 2002.

V. Bonhomme, D. Laurain-mattar, J. Lacoux, M. A. Fliniaux, and A. Jacquin-dubreuil, Tropane alkaloid production by hairy roots of Atropa belladonna obtained after transformation with Agrobacterium rhizogenes 15834 and Agrobacterium tumefaciens containing rol A , B , C genes only, Journal of Biotechnology, vol.81, issue.2-3, pp.151-158, 2000.
DOI : 10.1016/S0168-1656(00)00287-X

R. Bouami-guennouni-assimi, L. Cosson, and A. Et-jacquin-dubreuil, Selection and improvement of Datura innoxia Mill. ; Morphological variability in vitro propagated plants, Bull. Sco. Bot. Fr Let. Bot, vol.1375, issue.4, pp.261-269, 1990.

T. J. Bouma, K. L. Nielsen, and B. Koutstaal, Sample preparation and scanning protocol for computerised analysis of root length and diameter, Plant and soil, vol.218, pp.185-196, 2000.

F. Bourgaud, A. Gravot, and E. Gontier, Production of plant secondary metabolites: a historical perspective, Plant Science, vol.161, issue.5, pp.839-851, 2001.
DOI : 10.1016/S0168-9452(01)00490-3

F. Bourgaud, Etude de la biologie de plantes du genre Psoralea (Légumineuses), production de furocoumarines à intérêt pharmaceutique. Essais de cuture in-vitro, Thèse de doctorat, Institut National Polytechnique de Lorraine en Sciences Agronomiques, 1990.

S. A. Brown and C. Tabot, Green Fluorescent Protein (GFP) Seeking to be precise. LA biologie végétale face aux enjeux de la génomique fonctionnelle, 2003.

J. Bruneton, Pharmacognosie : Phytochimie ? Plantes médicinales, Lavoisier Eds, 1999.

J. Bruneton, Plantes toxiques, Végétaux dangeraux pour l'homme et les animaux, 1996.

J. P. Bryant, P. B. Reichardt, T. P. Clausem, and R. A. Werner, Effects of Mineral Nutrition on Delayed Inducible Resistance in Alaska Paper Birch, Ecology, vol.74, issue.7, pp.2072-2084, 1993.
DOI : 10.2307/1940853

L. Buchon, Etude de l'influence des phytohormones sur la différenciation cellulaire en relation avec la production d'alcaloïdes morphiniques par des cellules de Pavot (Papaver somniferum album) Effet des apports exogène en phytohormone ainsi que la transformation génétique par diverses souches d'Agrobacterium, 1996.

V. P. Bulgakov, M. V. Khodakovskaya, N. V. Labetskaya, G. K. Chernoded, and Y. N. Zhuravlev, The impact of plant rol C oncogene on ginsenoside production by giseng hairy root cultures, Phytochemistry, issue.7, pp.49-1929, 1998.

M. Cardarelli, L. Spano, D. Mariotti, M. L. Mauro, M. A. Van-sluys et al., Agrobacterium rhizogenes T-DNA genes capable of inducing hairy root phenotype, MGG Molecular & General Genetics, vol.186, issue.3, pp.457-480, 1987.
DOI : 10.1007/BF00331152

M. Cardarelli, L. Spano, D. Mariotti, M. L. Mauro, M. A. Van-sluys et al., The role of auxin in hairy root induction, Molecular and General Genetics MGG, vol.79, issue.3, pp.457-463, 1987.
DOI : 10.1007/BF00328139

M. Carolin and Y. O. , Analysis of the time course of change in nitrogen content in Dactylis glomerata L. using a model of plant growth, Ann Bot, vol.54, pp.69-76, 1994.

S. K. Chadhary, O. Ceska, P. J. Warrington, and M. J. Et-ashwood-smith, Increased furocoumarin content of celery during storage, Journal of Agricultural and Food Chemistry, vol.33, issue.6, pp.1153-1157, 1985.
DOI : 10.1021/jf00066a032

M. Chalfie, Y. Tu, G. Euskirchen, W. W. Ward, and D. C. Prasher, Green fluorescent protein as a marker for gene expression, Science, vol.263, issue.5148, pp.802-805, 1994.
DOI : 10.1126/science.8303295

M. D. Chilton, M. H. Drummond, D. J. Merlo, D. Sciaki, A. L. Montoya et al., Stable incorporation of plasmid DNA into higher plant cells: the molecular basis of crown gall tumorigenesis, Cell, vol.11, issue.2, pp.236-271, 1977.
DOI : 10.1016/0092-8674(77)90043-5

J. Chory, P. Nagpal, and C. A. Peto, Phenotypic and Genetic Analysis of det2, a New Mutant That Affects Light-Regulated Seedling Development in Arabidopsis, THE PLANT CELL ONLINE, vol.3, issue.5, pp.445-459, 1991.
DOI : 10.1105/tpc.3.5.445

P. Christen, M. F. Roberts, J. D. Phillipson, and W. C. Evans, Alkaloids of hairy root cultures of a Datura candida hybrid, Plant Cell Reports, vol.9, issue.2, pp.101-104, 1990.
DOI : 10.1007/BF00231559

C. Chun and T. Kozai, ARTIFICIAL LIGHTING FOR PRODUCING QUALITY TRANSPLANTS IN CLOSED SYSTEMS, Proc. 4 th IS on Artif, pp.43-47, 2002.
DOI : 10.17660/ActaHortic.2002.580.4

M. L. Cipollini, E. Paulk, and D. F. Cipollini, Effect of nitrogen and water treatment on leaf chemistry in horsenettle (Solanum carolinense), and relationship to herbivory by flea beetles (Epitrix spp.) and tobacco hornworm (i), Journal of Chemical Ecology, vol.28, issue.12, pp.2377-2398, 2002.
DOI : 10.1023/A:1021494315786

A. Cooper, The ABC of NFT, pp.181-224, 1979.

B. P. Cormack, R. Valdivia, and S. Falkow, FACS-optimized mutants of the green fluorescent protein (GFP), Gene, vol.173, issue.1, pp.33-38, 1996.
DOI : 10.1016/0378-1119(95)00685-0

P. Cornillon, Influence de la température des racines sur la croissance et la nutrition des plantes. Les a.t.p. de l'INRA d'Avignon : les cultures hors sol, pp.221-234, 1985.

L. Cosson, E. Morales, A. Et-cougoul, and N. , La régulation écophysiologiques du métabolisme des alcaloïdes tropaniques (hyoscyamine et scopolamine), Ph. Méd. Et Phyt., XII, vol.4, pp.219-326, 1978.

L. Cosson, Importance des facteurs climatiques et des étapes du développement dans la productivité des alcaloïdes tropaniques, Etudes de Biologie Végéale, R. Jaques Edit, pp.483-494, 1976.

L. Cosson, Influence de l'éclairement sur la teneur en alcaloïdes tropaniques des Datura : analyse des processus pouvant en expliquer les effets, 1972.

N. Cougoul, E. Miginiac, and L. Et-cosson, Un gradient metabolique: Rapport scopolamine/hyoscyamine dans les feuilles du Duboisia myoporoides en fonction de leur niveau d'insertion et du stade de croissance, Phytochemistry, vol.18, issue.6, pp.949-951, 1979.
DOI : 10.1016/S0031-9422(00)91455-9

G. M. Cragg, D. J. Newman, and K. M. Snader, Natural Products in Drug Discovery and Development, Journal of Natural Products, vol.60, issue.1, pp.52-60, 1997.
DOI : 10.1021/np9604893

R. Croteau, T. M. Kutchan, and N. G. Lewis, Natural Products (Secondary metabolites), 2000.

R. M. Cusido, J. Palazón, M. T. Piñol, M. Bonfill, and C. Et-morales, Datura metel: In Vitro Production of Tropane Alkaloids, Planta Medica, vol.65, issue.2, pp.144-148, 1998.
DOI : 10.1055/s-1999-13976

H. Daniel, S. J. Streatfield, and . Wycoff, Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants, Trends in Plant Science, vol.6, issue.5, pp.219-226, 2001.
DOI : 10.1016/S1360-1385(01)01922-7

C. Dechaux-duval, Modulation de la voie de biosynthèse de la scopolamine chez Datura innoxia Mil. : Expression du gène h6h d'Hyoscyamus niger dans des racines transgénique obtenues par transformation via Agrobacterium rhizogenes, Thèse de doctorat, p.142, 2005.

K. Demeyer and R. Et-dejaegere, The Influence of the Ca2+/K+ Balance and Light Energy on Alkaloid Content and Parttioning in Datura stramonium, Australian Journal of Botany, vol.45, issue.1, pp.81-101, 1997.
DOI : 10.1071/BT94049

K. Dermeyer and R. Et-dejaegere, Influence of the ion-balance in the growth medium on the yield and alkaloid content ofDatura stramonium L., Plant and Soil, vol.37, issue.2, pp.289-294, 1989.
DOI : 10.17660/ActaHortic.1978.73.22

K. Dermeyer, H. Van-de-velde, and R. Et-dejaegere, Influence of IAA and DMAA on hyoscyamine and scopolamine production in Datura stramonium L, Med. Fac. Landbouww. Rijksuniv. Gent, vol.54, issue.4, pp.1313-1318, 1989.

I. Desailly, M. A. Fliniaux, and A. Et-jacquin-dubreuil, Etude de la distribution des alcaloïdes dérivés de l'acide tropique chez Datura stramonium L. par dosage immunoenzymatique : localisation tissulaire et subcellulaire, C.R. Acad Sci. Paris Série III, vol.306, pp.591-596, 1988.

Y. Dessaux, A. Petit, and J. Tempé, Chemistry and biochemistry of opines, chemical mediators of parasitism, Phytochemistry, vol.34, issue.1, pp.31-38, 1993.
DOI : 10.1016/S0031-9422(00)90778-7

M. F. Diop, Etude de l'impact de la différenciation cellulaire sur la biosynthèse et l'accumulation de la galanthamine chez Leucojum aestivum L. (Amaryllidaceae), Thèse de doctorat, p.130, 2007.

M. F. Diop, A. Hehn, A. Ptak, F. Chrétien, S. Doerper et al., Hairy root and tissue cultures of Leucojum aestivum L.???relationships to galanthamine content, Phytochemistry Reviews, vol.6, issue.(12, pp.137-141, 2007.
DOI : 10.1111/j.1438-8677.1996.tb00553.x

URL : https://hal.archives-ouvertes.fr/hal-01738283

S. H. Doares, T. Syrovets, E. W. Weiller, and C. A. Ryan, Oligalacturonides and chitosan activate plant defensive genes through the octadecanoid pathway, Proc. Natl. Acad. Sci. USA, pp.4095-4098, 1995.

M. Dorais and A. Gosselin, PHYSIOLOGICAL RESPONSE OF GREENHOUSE VEGETABLE CROPS TO SUPPLEMENTAL LIGHTING, Proc. 4 th IS on Artif, pp.59-67, 2002.
DOI : 10.17660/ActaHortic.2002.580.6

P. Duez, S. Chamart, M. Hanocq, L. Molle, M. Vanhaelen et al., Comparison between thin-layer chromatography???densitometry and high-performance liquid chromatography for the determination of hyoscyamine and hyoscyne in leaves, fruit and seeds of Datura (Datura spp.), Journal of Chromatography A, vol.329, pp.415-421, 1985.
DOI : 10.1016/S0021-9673(01)81949-X

E. D. Fajer, M. D. Bower, and F. A. Bazzaz, Environments on Production of Carbon-Based Allelochemicals in Plantago: A Test of the Carbon/Nutrient Balance Hypothesis, The American Naturalist, vol.140, issue.4, pp.707-723, 1992.
DOI : 10.1086/285436

N. R. Farnsworth and D. D. Et-soejarto, Conservation of medicinal plants, pp.25-52, 1991.

L. Faye, N. Landry, P. Lerouge, V. Gomord, and L. P. Vézina, La production de prot??ines ?? usage biopharmaceutique dans les plantes., m??decine/sciences, vol.17, issue.8-9, pp.867-877, 2001.
DOI : 10.4267/10608/2021

F. Filippini, F. Lo-schiavo, M. Terzi, P. Costantino, and M. Trovato, The Plant Oncogene rolB Alters Binding of Auxin to Plant Cell Membranes, Plant and Cell Physiology, vol.35, issue.5, pp.767-771, 1994.
DOI : 10.1093/oxfordjournals.pcp.a078655

M. Fincan, F. Devito, and P. Dejmek, Pulsed electric field treatment for solid???liquid extraction of red beetroot pigment, Journal of Food Engineering, vol.64, issue.3, pp.381-388, 2004.
DOI : 10.1016/j.jfoodeng.2003.11.006

G. Freyssinet, M. Lebrun, B. Pelissier, and T. Hardy, Biotechnologies végétales, Biotechnologies d'aujourd'hui. Julien R. et Cenatiempo Y. Eds, Limoges, pp.163-198, 1993.

C. Fritz, N. Palacios-rojas, R. Feil, and M. Stitt, Regulation of secondary metabolism by the carbon-nitrogen status in tobacco: nitrate inhibits large sectors of phenylpropanoid metabolism, The Plant Journal, vol.7, issue.4, pp.533-548, 2006.
DOI : 10.1016/0304-4165(78)90223-4

C. X. Fu, D. X. Zhao, X. F. Xue, Z. P. Jin, and F. S. Ma, Transformation of Saussurea involucrata by Agrobacterium rhizogenes: Hairy root induction and syringin production, Process Biochemistry, vol.40, issue.12, pp.3789-3794, 2005.
DOI : 10.1016/j.procbio.2005.03.063

O. L. Gamborg, R. A. Miller, and K. Ojima, Nutrient requirements of suspension cultures of soybean root cells, Experimental Cell Research, vol.50, issue.1, pp.151-158, 1968.
DOI : 10.1016/0014-4827(68)90403-5

V. Gaudin, T. Vrain, and L. Jouanin, Bacterial genes modifying hormonal balances in plants, Plant Physiol. Biochem, vol.32, pp.11-29, 1994.

A. Giri, S. T. Ravindra, V. Dhingra, and M. L. Narusu, Influence of different strains of Agrobacterium rhizogenes on induction of hairy root and artermisinin production in Artemisia annua, Current Science, vol.81, issue.4, pp.378-382, 2001.

A. Giri and M. N. Narasu, Transgenic hairy roots, Biotechnology Advances, vol.18, issue.1, pp.1-22, 2000.
DOI : 10.1016/S0734-9750(99)00016-6

O. J. Goddijn, D. Kam, R. J. Zanetti, A. Schilperoort, A. Hoge et al., Auxin rapidly down-regulates transcription of the tryptophan decarboxylase gene from Catharanthus roseus, Plant Molecular Biology, vol.2, issue.6, pp.1113-1120, 1992.
DOI : 10.1007/BF00047714

E. Gontier, S. Piutti, A. Gravot, S. Milesi, A. Grabner et al., Development and validation of an efficient low cost bioreactor for furanocoumarin production with Ruta graveolens shoot cultures, pp.509-524, 2004.
DOI : 10.1007/1-4020-3200-5_38

E. Gontier, A. Clément, T. L. Tran, A. Gravot, K. Lièvre et al., Hydroponic combined with natural or forced root permeabilization: a promising technique for plant secondary metabolite production, Plant Science, vol.163, issue.4, pp.723-732, 1963.
DOI : 10.1016/S0168-9452(02)00171-1

E. Gontier, A. Clément, F. Bourgaud, and A. Et-guckert, Procédé de production de métabolites à partir de plantes, pp.99-14204, 1999.

E. Gontier, Biotechnologies et valorisation des productions végétales : une démarche de type « génie métabolique » appliquée aux alcaloïdes, aux furanocoumarines et aux triglycérides, Mémoire de l'Habilitation à Diriger des Recherches, spécialité en Sciences Agronomiques à l'INPL, 2001.

E. Gontier, B. S. Sangwan, and J. N. Et-barbotin, Simultaneous determination of some tropane alkaloids by reverse phase HPLC of Datura innoxia Mill, pp.26-28, 1994.

E. Gontier, Etude de la production d'alcaloïdes tropaniques chez le Datura innoxia Mill. cultivé in vitro : impact physiologique de l'immobilisation des cellules au sein d'une matrice d'alginate de calcium, Thèse de doctorat, 1993.

E. Gontier, Etude de la production d'alcaloïdes tropaniques chez le Datura innoxia Mill. cultivé in vitro. Essais d'immobilisation au sein d'une matriced'alginate de calcium, p.35, 1988.

D. J. Greenwood, J. J. Neeteson, and A. Draycott, Quantitative relationships for the dependence of growth rate of arable crops on their nitrogen content, dry weight and aerial environment, Plant and Soil, vol.64, issue.6, pp.281-301, 1986.
DOI : 10.1111/j.1365-3040.1981.tb01048.x

A. Guckert, J. L. Morel, . Arissian, S. Herbin, and A. Blouet, Etude en phytotron d'une association a base d'imazaquin. Deuxième colloque sur les substances de croissance et leurs utilisations en agriculture, pp.11-22, 1987.

R. Habib, Quelques réflexions concernant les problèmes de fertilisation en culture irriguées. Fruits, pp.381-389, 1988.

J. Hakulinen, Nitrogen-induced reduction in leaf phenolic level is not accompanied by increased rust frequency in a compatible willow (Salix myrsinifolia)-Melampsora rust interaction, Physiologia Plantarum, vol.102, issue.1, pp.101-110, 1998.
DOI : 10.1034/j.1399-3054.1998.1020114.x

F. Hamel, C. Breton, and M. Et-houde, Isolation and characterization of wheat aluminum-regulated genes: possible involvement of aluminum as a pathogenesis response elicitor, Planta, vol.205, issue.4, pp.531-538, 1998.
DOI : 10.1007/s004250050352

J. D. Hamill, A. J. Parr, M. J. Rhodes, R. J. Robins, and N. J. Walton, New Routes to Plant Secondary Products, Nature Biotechnology, vol.72, issue.8, pp.800-804, 1987.
DOI : 10.1016/S0031-9422(00)81107-3

G. Hansen and M. S. Wright, Recent advances in the transformation of plants, Trends in Plant Science, vol.4, issue.6, pp.226-231, 1999.
DOI : 10.1016/S1360-1385(99)01412-0

Y. Hara, T. Yoshioka, T. Morimoto, Y. Fujita, and Y. Yamada, Enhancement of Berberine Production in Suspension Cultures of Coptis japonica by Gibberellic Acid Treatment, Journal of Plant Physiology, vol.133, issue.1, pp.12-15, 1988.
DOI : 10.1016/S0176-1617(88)80077-4

H. Harssema, Root temperature and growth o young tomato plants, p.85, 1977.

J. Haseloff and K. R. Siemering, The uses of GFP in plants, Green Fluorescent Protein. Strategies, Applications and Protocols, pp.191-220, 1998.

T. Hashimoto, F. Sato, M. Mino, and Y. Yamada, Production of tropane alkaloids from cultured Solanaceae cells, Proc. 5 th, pp.305-306, 1982.

T. Hashimoto, J. Masuda, and Y. Yamada, Two-step epoxidation of hyoscyamine to scopolamine is catalyzed by bifunctional hyoscyamine 6??-hydroxylase, FEBS Letters, vol.62, issue.1-2, pp.35-39, 1993.
DOI : 10.1007/BF00592185

T. Hashimoto, A. Hayashi, Y. Amano, J. Kohno, H. Iwanari et al., Hyoscyamine 6?-Hydroxyase, an enzyme involved in tropane alkaloid biosynthesis, is localized in the pericycle f the root, J. Biol. Chem, vol.266, issue.5, pp.4648-4653, 1991.

T. Hashimoto and Y. Yamada, Hyoscyamine 6??-Hydroxylase, a 2-Oxoglutarate-Dependent Dioxygenase, in Alkaloid-Producing Root Cultures, PLANT PHYSIOLOGY, vol.81, issue.2, pp.619-625, 1986.
DOI : 10.1104/pp.81.2.619

R. Heim, D. C. Prasher, and R. Y. Tsien, Wavelength mutations and posttranslational autoxidation of green fluorescent protein., Proceedings of the National Academy of Sciences, vol.91, issue.26, pp.12501-12504, 1994.
DOI : 10.1073/pnas.91.26.12501

E. B. Herman, Recent advances in plant tissue culture II. Agritech consultants, INC, p.116, 1993.

D. Herouart, R. S. Sangwan, M. A. Fliniaux, and B. S. Et-sangwan-norreel, Variations in the leaf alkaloid content of androgenic diploid plants of Datura innoxia, Planta Med, vol.1, issue.94, pp.14-17, 1988.

J. Hille, A. Hoekema, P. Hooykaas, and R. A. Schilperoort, Gene Organization of the Ti-Plasmid, Genes involved in microbe-plant interactions. Verma D. P. S. and Hohn, pp.287-309, 1984.
DOI : 10.1007/978-3-7091-8739-5_11

P. J. Hooykaas and R. A. Schilperoort, Agrobacterium and plant genetic engineering, Plant Molecular Biology, vol.167, issue.1, pp.15-38, 1992.
DOI : 10.1126/science.242.4880.927

P. J. Hooykaas, P. M. Klapwijk, and M. P. Nuti, Transfer of the Agrobacterium tumefaciens TI Plasmid to Avirulent Agrobacteria and to Rhizobium ex planta, Journal of General Microbiology, vol.98, issue.2, pp.477-484, 1977.
DOI : 10.1099/00221287-98-2-477

W. G. Hopkins, Assimilation du carbone et productivité, Physiologie végétale. Traduction de la 2ème édition américaine par Serge Rambour. Editions De Boeck université, p.515, 2003.

Z. Hromádková and A. Ebringerová, Ultrasonic extraction of plant materials??????investigation of hemicellulose release from buckwheat hulls, Ultrasonics Sonochemistry, vol.10, issue.3, pp.127-133, 2003.
DOI : 10.1016/S1350-4177(03)00094-4

B. J. Jansen and R. C. Gardner, Localized transient expression of GUS in leaf discs following cocultivation with Agrobacterium, Plant Molecular Biology, vol.22, issue.1, pp.61-72, 1989.
DOI : 10.1007/BF00015655

M. Jaziri, K. Yoshimatsu, and K. Et-shimomura, Genetic Transformation of Atropa belladonna, Biotechnology in Agriculture and Forestry, vol.45, pp.73-87, 1999.
DOI : 10.1007/978-3-642-58439-8_5

B. Jeannequin, F. Dosba, and M. J. Amiot-carlin, Fruits et légumes, caractéristiques et principaux enjeux, Publié par l'Institut National de la Recherche Agronomique, p.114, 2005.

R. A. Jefferson, Assaying chimeric genes in plants: The GUS gene fusion system, Plant Molecular Biology Reporter, vol.313, issue.4, pp.387-405, 1987.
DOI : 10.1128/MCB.2.9.1044

E. Juste, B. Mary, J. M. Meynard, J. M. Machet, and L. Thelier-huches, Determination of a Critical Nitrogen Dilution Curve for Winter Wheat Crops, Annals of Botany, vol.74, issue.4, pp.397-407, 1994.
DOI : 10.1006/anbo.1994.1133

H. Keller, H. Hohlfeld, V. Wray, K. Hahlbrock, D. Scheel et al., Changes in the accumulation of soluble and cell wall-bound phenolics in elicitor-treated cell suspension cultures and fungus-infected leaves of Solanum tuberosum, Phytochemistry, vol.42, issue.2, pp.389-396, 1996.
DOI : 10.1016/0031-9422(95)00866-7

K. J. Kerters, D. Ley, and J. , Genus Agrobacterium. In Bergey's Manual of Systematic Bacteriology, pp.244-254, 1984.

A. D. Kinghorn and M. Balandrin, Human medicinal agents from plants. Washington: ACS Symposium Series 534 Change of atropine esterase activity in the regenerated plants of Duboisia myoporoides during development, and its relation to alkaloid accumulation, Kitamura Y., Miura H. and Sugii M. J. Plant Physiol, vol.119, issue.133, pp.316-319, 1988.

Y. Kitamura, S. Nishimi, H. Miura, and T. Kinoshita, Phenyllactic acid in Duboisia leichhardtii root cultures B feeding of phenyl[1-14C]alanine, Phytochemistry, vol.34, issue.2, pp.425-427, 1993.
DOI : 10.1016/0031-9422(93)80022-K

D. Knorr and A. Angersbach, Impact of high-intensity electric field pulses on plant membrane permeabilization, Trends in Food Science & Technology, vol.9, issue.5, pp.185-191, 1998.
DOI : 10.1016/S0924-2244(98)00040-5

K. Komolpis, P. B. Kaufman, and H. Y. Wang, Chemical permeabilization and in situ removal of daidzein from biologically viable soybean (Glycine max) seeds, Biotechnology Techniques, vol.12, issue.9, pp.697-700, 1998.
DOI : 10.1023/A:1008817104926

H. A. Kratsch, W. R. Graves, and R. J. Gladon, Aeroponic system for control of root-zone atmosphere, Environmental and Experimental Botany, vol.55, issue.1-2, pp.70-76, 2006.
DOI : 10.1016/j.envexpbot.2004.10.002

S. Kumar, S. K. Gupta, P. Singh, P. Bajpai, M. M. Gupta et al., High yields of artemisinin by multi-harvest of Artemisia annua crops, Industrial Crops and Products, vol.19, issue.1, pp.77-90, 2004.
DOI : 10.1016/j.indcrop.2003.07.003

M. E. Landgrebe and E. Et-leete, The metabolism of tropinone in intact Datura innoxia plants, Phytochemistry, vol.29, issue.8, pp.2521-2524, 1990.
DOI : 10.1016/0031-9422(90)85179-J

A. Lanoue, Etude de la biosynthèse et de la production d'alcaloïdes tropaniques par les racines transgéniques de Datura, Thèse de l Sciences Biologiques en Sciences Biologiques, p.151, 2003.

A. Lanoue, M. Boitel-conti, J. C. Portais, J. N. Barbotin, P. Christen et al., Kinetic study of littorine rearrangement in Datura innoxia hairy root by 13, 2002.

L. Bot, J. Adamowicz, S. Et-robin, and P. , Nutrition minérale chez les herbacées. Un point de vue sur les modèles, 1997.

N. I. Lebovka, M. I. Bazhal, and E. Vorobiev, Pulsed electric field breakage of cellular tissues: visualisation of percolative properties, Innovative Food Science & Emerging Technologies, vol.2, issue.2, pp.113-125, 2001.
DOI : 10.1016/S1466-8564(01)00024-8

K. T. Lee, T. Yamakawa, T. Kodama, Y. Igarashi, and K. Shimomura, Effects of aeration on tropane alkaloid production by transformed root of Atropa belladonna in flask cultures, Journal of Fermentation and Bioengineering, vol.86, issue.6, pp.614-616, 1998.
DOI : 10.1016/S0922-338X(99)80018-X

E. Leete, N. Kowenko, and R. A. Newark, Use of carbon-13 nuclear magnetic resonance to establish that the biosynthesis of tropic acid involves an intramolecular rearrangement of phenylalanine, Journal of the American Chemical Society, vol.97, issue.23, pp.6826-6830, 1975.
DOI : 10.1021/ja00856a038

E. Leete, Alkaloid biogenesis ? Tropane alkaloids Biogenesis of natural compounds, Ed. Bernfeld P, pp.745-746, 1963.

G. Lemaire and F. Gastal, N Uptake and Distribution in Plant Canopies, Diagnosis of the nitrogen status in, pp.3-43, 1997.
DOI : 10.1007/978-3-642-60684-7_1

G. Lemaire and J. M. Meynard, Use of the Nitrogen Nutrition Index for the Analysis of Agronomical Data, Diagnosis of the nitrogen status in, pp.45-56, 1997.
DOI : 10.1007/978-3-642-60684-7_2

S. Léonhart, K. Pedneault, and A. Gosselin, DIVERSIFICATION OF GREENHOUSE CROP PRODUCTION UNDER SUPPLEMENTAL LIGHTING BY THE USE OF NEW CULTURES WITH HIGH ECONOMIC POTENTIAL, Acta Horticulturae, vol.580, issue.580, pp.249-254, 2002.
DOI : 10.17660/ActaHortic.2002.580.33

C. Lesaint, M. Grandjean, and J. Gambier, Influence de l'aération du milieu nutritif sur l'absorption de l'eau et des ions, la nuite et le jour Comparaison du maïs et de la tomate, C. R. Acad. Agric, vol.6, pp.399-406, 1983.

M. Letard, P. Erard, and B. Jannequin, Maîtrise de l'irrigation fertilisation ? Tomate sous serre et abris, p.220, 1995.

X. Li, X. Zhao, Y. Fang, X. Jiang, T. Duong et al., Generation of Destabilized Green Fluorescent Protein as a Transcription Reporter, Journal of Biological Chemistry, vol.1, issue.52, pp.34970-34975, 1998.
DOI : 10.1038/365182a0

H. K. Lichtenthaler, [34] Chlorophylls and carotenoids: Pigments of photosynthetic biomembranes, Methods in Enzymology, vol.148, pp.350-382, 1987.
DOI : 10.1016/0076-6879(87)48036-1

K. Lièvre, Elaboration d'une méthode de transformation génétique de la Rue officinale (Ruta graveolens L.) par Agrobacterium tumefaciens. Conséquence de l'introduction du gène de la cinnamate-4-hydroxylase sur la voie de biosynthèse des furocoumarines chez Ruta graveolens L, Thèse de Doctorat de l'Institut National de Polytechnique de Lorraine en Sciences Agronomiques en Sciences Agronomiques, p.181, 2004.

G. M. Liu, W. S. Fang, J. F. Quian, and H. Lan, Distribution of paclitaxel and its congeners in Taxus mairei, Fitoterapia, vol.72, issue.7, pp.743-746, 2001.
DOI : 10.1016/S0367-326X(01)00302-1

Y. Lou and I. T. Baldwin, Nitrogen Supply Influences Herbivore-Induced Direct and Indirect Defenses and Transcriptional Responses in Nicotiana attenuata, PLANT PHYSIOLOGY, vol.135, issue.1, pp.496-506, 2004.
DOI : 10.1104/pp.104.040360

J. Luo and G. Y. He, Optimization of elicitors and precursors for paclitaxel production in cell suspension culture of Taxus chinensis in the presence of nutrient feeding, Process Biochemistry, vol.39, issue.9, pp.1073-1079, 2004.
DOI : 10.1016/S0032-9592(03)00219-X

G. Mackinney, Absorption of light by chlorophyll solutions, J. Biol. Chem, vol.140, pp.315-322, 1941.

C. Maurel, H. Barbier-brygoo, A. Spena, J. Tempé, and J. Guern, Single rol Genes from the Agrobacterium rhizogenes TL-DNA Alter Some of the Cellular Responses to Auxin in Nicotiana tabacum, PLANT PHYSIOLOGY, vol.97, issue.1, pp.212-216, 1991.
DOI : 10.1104/pp.97.1.212

C. Maurel, N. Leblanc, H. Barbier-brygoo, C. Perrot-rechenmann, M. Bouvier-durand et al., Alterations of Auxin Perception in rolB-Transformed Tobacco Protoplasts (Time Course of rolB mRNA Expression and Increase in Auxin Sensitivity Reveal Multiple Control by Auxin), Plant Physiology, vol.105, issue.4, pp.1209-1215, 1994.
DOI : 10.1104/pp.105.4.1209

E. Miraldi, A. Masti, S. Ferri, and I. B. Comparini, Distribution of hyoscyamine and scopolamine in Datura stramonium, Fitoterapia, vol.72, issue.6, pp.644-648, 2001.
DOI : 10.1016/S0367-326X(01)00291-X

P. Morard, Les cultures végétales hors sol, Publications Agricoles Agen, p.304, 1995.

E. Moyano, . Jouhikainen-k, P. Tammela, J. Palazón, R. M. Cusidó et al., Effect of pmt gene overexpression on tropane alkaloid production in transformed root cultures of Datura metel and Hyoscyamus muticus, Journal of Experimental Botany, vol.3, issue.3, pp.203-211, 2003.
DOI : 10.1007/BF00270196

T. Murashige and F. Skoog, A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures, Physiologia Plantarum, vol.7, issue.3, pp.473-497, 1962.
DOI : 10.1146/annurev.pp.02.060151.001311

N. Nadeem, M. Rikhari, H. C. Kumar-anil, L. M. Palni, and S. K. Nandi, Taxol content in the bark of Himalayan Yew in relation to tree age and sex, Phytochemistry, vol.60, issue.6, pp.627-631, 2002.
DOI : 10.1016/S0031-9422(02)00115-2

K. Nakajima and T. Hashimoto, Two Tropinone Reductases, That Catalyze Opposite Stereospecific Reductions in Tropane Alkaloid Biosynthesis, Are Localized in Plant Root with Different Cell-Specific Patterns, Plant and Cell Physiology, vol.40, issue.11, pp.1099-1107, 1999.
DOI : 10.1093/oxfordjournals.pcp.a029494

F. Nakanishi, K. Sasaki, and K. Shimomura, Kinetics of littorine content in various developing stages of regenerates of Atropa belladonna, Plant Cell Reports, vol.19, issue.10, pp.1021-1026, 2000.
DOI : 10.1007/s002990000231

C. Nguyen, Rhizodeposition of organic C by plants: mechanisms and controls, Agronomie, vol.23, issue.5-6, pp.375-396, 2003.
DOI : 10.1051/agro:2003011

URL : https://hal.archives-ouvertes.fr/hal-00886190

O. Oksman-caldentley, K. M. Vuorela, H. Straub, A. Hiltunen, and R. , Variation in the tropane alkaloid content of Hyoscyamus muticus plants and cell culture clones, Planta Med, vol.6, pp.394-354, 1987.

C. M. Olympios, Overview of soilless culture: Advantages, constraints and perspectives for its use in Mediterranean countries, Cahiers Options Méditerranéennes, vol.31, pp.307-324, 1975.

O. 'hagan, D. Et-robins, and R. J. , Tropic acid ester biosynthesis in Datura stramonium and related species, Chemic. Soc. Reviews, vol.27, pp.207-212, 1998.

J. Palazon, E. Moyano, R. M. Cusido, M. Bonfill, K. M. Oksman-caldentey et al., Alkaloid production in Duboisia hybrid hairy roots and plants overexpressing the h6h gene, Plant Science, vol.165, issue.6, pp.1289-1295, 2003.
DOI : 10.1016/S0168-9452(03)00340-6

J. Palazon, R. M. Cusido, C. Roig, and M. T. Pinol, Effect of rol genes from Agrobacterium rhizogenes TL-DNA on nicotine production in tobacco root cultures, Plant Physiol. Biochem, vol.35, issue.2, p.155162, 1997.

J. Palazon, R. M. Cusido, J. Gonzalo, M. Bonfill, C. Morales et al., Relation between the amount of rolC gene product and indole alkaloid accumulation in Catharanthus roseus transformed root cultures, Journal of Plant Physiology, vol.153, issue.5-6, pp.712-718, 1998.
DOI : 10.1016/S0176-1617(98)80225-3

G. Palomino, R. Viveros, and R. A. Bye, Cytology of Five Mexican Species of Datura L. (Solanaceae), The Southwestern Naturalist, vol.33, issue.1, pp.85-90, 1988.
DOI : 10.2307/3672092

A. J. Parr, J. Payne, J. Eagles, B. T. Chapman, R. J. Robins et al., Variation in tropane alkaloid accumulation within the solanaceae and strategies for its exploitation, Phytochemistry, vol.29, issue.8, pp.2545-2550, 1990.
DOI : 10.1016/0031-9422(90)85185-I

A. J. Parr, J. D. Hamill, M. J. Rhodes, R. J. Robin, V. W. Walton et al., Exploiting variation in tropane alkaloid production by Solanaceous plats In: Manipulating secondary metabolisme in culture, pp.101-107, 1988.

M. A. Pathak, D. J. Farrington, and T. B. Fitzpatrick, The Presently Known Distribution of Furocoumarins (Psoralens) in Plants, Journal of Investigative Dermatology, vol.39, issue.3, pp.225-299, 1962.
DOI : 10.1038/jid.1962.106

G. F. Payne, V. Bringi, C. Prince, and M. L. Et-shuler, Immobilized plant cells, Plant Cell and Tissue in liquid systems, pp.179-223, 1991.

K. Pedneault, S. Léonhart, and A. Gosselin, Variations in Concentration of Active Compounds in Four Hydroponically ? and Fiels-Grown Medicinal Plant Species, Proc. 4 th IS on Artif. Light. Ed. Dorias, Acta Hort, 2002.

S. W. Pelletier, The nature and definition of an alkaloid, Alkaloids: chemical and biological perspectives, pp.1-31, 1983.

A. Petit, C. David, G. A. Dahl, J. G. Ellis, and P. Guyon, Further extension of the opine concept: Plasmids in Agrobacterium rhizogenes cooperate for opine degradation, MGG Molecular & General Genetics, vol.86, issue.2, pp.204-214, 1983.
DOI : 10.1016/0304-4165(66)90256-X

A. Petit, S. Delahaye, J. Tempé, and G. Morel, Recherches sur les guanidines des tissus de crown gall. Mise en évidence d'une relation biochimique spécifique entre les souches d'Agrobacterium tumefaciens et les tumeurs qu'elles induisent, Physiol. Veg, vol.8, p.205, 1970.

M. T. Pinol, J. Palazon, R. Cusido, and M. Serrano, Root Cultures, Botanica Acta, vol.1, issue.2, pp.133-138, 1996.
DOI : 10.1007/BF00272363

S. I. Pitta-alvarez and A. M. Giulietti, Influence of chitosan, acetic acid on growth and tropane alkaloid production in transformed roots of Brugmansia candida effect of medium pH and growth phase, Plant Cell, Tissue and Organ Culture, vol.59, issue.1, pp.31-38, 1999.
DOI : 10.1023/A:1006359429830

K. H. Plant and K. G. Wagner, Determination of Hyoscyamine and Scopolamine in Datura innoxia plants by high performance liquid chromatography, Z. Naturforsch, vol.41, pp.391-395, 1986.

A. Portsteffen, B. Draeger, and A. Nahrstedt, The reduction of tropinone in Datura stramonium root cultures by two specific reductases, Phytochemistry, vol.37, issue.2, pp.391-400, 1994.
DOI : 10.1016/0031-9422(94)85066-6

A. Poulev, J. M. O-'neal, S. Logendra, R. B. Pouleva, V. Timeva et al., Elicitation, a New Window into Plant Chemodiversity and Phytochemical Drug Discovery, Journal of Medicinal Chemistry, vol.46, issue.12, pp.2542-2547, 2003.
DOI : 10.1021/jm020359t

K. Pundarikakshudu and G. C. Bhavsar, Effects of ascorbic acid on the tropane alkaloids of Datura innoxia Mill, Indian Drugs, vol.26, issue.11, pp.605-609, 1989.

R. Raven, H. Evert, R. F. Eichhorn, and S. E. , Biologie végétale. 6 e édition. Traduit par Jules Bouharmont avec la collaboration scientifique de Charles-Marie Evrard Studies on infectious hairy root of nursery apple trees, J. Agric. Rec, vol.41, pp.944-182387, 1930.

M. F. Roberts, D. Carthy, . Mc, M. M. Kutchan, and C. J. Coscia, Localization of enzymes and alkaloidal metabolites in Papaver latex, Archives of Biochemistry and Biophysics, vol.222, issue.2, pp.599-609, 1983.
DOI : 10.1016/0003-9861(83)90558-1

R. J. Robin, A. J. Parr, J. Payne, N. J. Walton, and M. J. Rhodes, Factor regulating tropane alkaloid production in a transformed root culture of D, pp.414-422, 1990.

R. J. Robin, A. J. Parr, E. G. Ben, N. J. Walton, and M. J. Rhodes, Studies on the biosynthesis of tropane alkaloids in Datura stramonium L. transformed root cultures, Planta, vol.182, issue.2, pp.185-195, 1991.
DOI : 10.1007/BF00239995

R. J. Robin, The Biosynthesis of Alkaloids in Root Cultures, pp.199-218, 1998.
DOI : 10.1007/978-1-4757-2905-4_8

A. Romeike, Sur la biogenèse de la scopolamine, Bull. Sco. Fr. Phys. Veg, vol.7, pp.33-35, 1961.

S. Sallas, L. Kainulainen, P. Utriainen, J. Holopainen, T. Et-holopainen et al., The influence of elevated O3 and CO2 concentrations on secondary metabolites of Scots pine (Pinus sylvestris L. ) seedlings, Global Change Biology, vol.98, issue.3, pp.303-311, 2001.
DOI : 10.1007/BF00326091

B. Samia, Influence de la température et de l'aération des racines sur l'absorption des éléments minéraux par la tomate Lycopersicon esculentum L, p.40, 1992.

F. Sato, T. Hashimoto, A. Hachiya, K. I. Tamura, K. B. Choi et al., Metabolic engineering of plant alkaloid biosynthesis, Proc. Natl. Acad, 2001.
DOI : 10.1016/0014-5793(93)80187-Y

M. Sauerwein and K. Shimomura, Alkaloid production in hairy roots of Hyoscyamus albus transformed with Agrobacterium rhizogenes, Phytochemistry, vol.30, issue.10, pp.3277-3280, 1991.
DOI : 10.1016/0031-9422(91)83192-N

T. Schmeller and M. Wink, Alkaloids in Modern Medecine in Alkaloids: Biochemistry, Ecology, and Medicinal Applications, p.477, 1998.

N. Sevon, B. Dragër, R. Hiltunen, and K. M. Oksman-caldentey, Characterization of transgenic plants derived from hairy roots ofHyoscyamus muticus, Plant Cell Reports, vol.58, issue.9, pp.605-611, 1997.
DOI : 10.1007/BF01275500

T. L. Shiao and P. M. Doran, Root hairiness: effect on fluid flow and oxygen transfer in hairy root cultures, Journal of Biotechnology, vol.83, issue.3, pp.199-210, 2000.
DOI : 10.1016/S0168-1656(00)00316-3

J. Sierra, Etude des mécanismes de croissance des racines Datura innoxia : application à la culture en bioréacteur avec divers modes de conduites, Thèse de doctorat, 2007.

S. J. Sim, H. N. Chang, J. R. Liu, and K. H. Jung, Production and secretion of indole alkaloids in hairy root cultures of Catharanthus roseus: Effects of in situ adsorption, fungal elicitation and permeabilization, J. of Ferment. and Bioeng, vol.78, pp.229-234, 1994.

E. F. Smith and C. O. Townsend, A PLANT-TUMOR OF BACTERIAL ORIGIN, Science, vol.25, issue.643, pp.671-673, 1907.
DOI : 10.1126/science.25.643.671

I. E. Somssich and K. Et-hahlbrock, Pathogen defence in plants ??? a paradigm of biological complexity, Trends in Plant Science, vol.3, issue.3, pp.86-90, 1998.
DOI : 10.1016/S1360-1385(98)01199-6

T. C. Spollansky, S. I. Pitta-alvarez, and A. M. Giulietti, Effect of jasmonic acid and aluminium on production of tropane alkaloids in hairy root cultures of Brugmansia candida, EJB Electronic J. of Biotechnol, vol.3, pp.72-75, 2000.

F. Sporer, M. Sauerwein, and M. Wink, DIURNAL AND DEVELOPMENTAL VARIATION OF ALKALOID ACCUMULATION IN ATROPA BELLADONNA, Acta Horticulturae, vol.331, issue.331, pp.381-386, 1993.
DOI : 10.17660/ActaHortic.1993.331.53

Y. Sreevalli, R. N. Kulkarni, K. Baskaran, and R. S. Chandrashekara, Increasing the content of leaf and root alkaloids of high alkaloid content mutants of periwinkle through nitrogen fertilization, Industrial Crops and Products, vol.19, issue.2, pp.191-195, 2004.
DOI : 10.1016/j.indcrop.2003.09.005

W. W. Su, Bioprocessing technology for plant cell suspension cultures, Applied Biochemistry and Biotechnology, vol.23, issue.2, pp.189-230, 1995.
DOI : 10.1007/978-94-009-2103-0_90

M. A. Subroto, K. H. Kwork, J. D. Hamill, and P. M. Doran, Coculture of genetically transformed roots and shoots for synthesis, translocation, and biotransformation of secondary metabolites, Biotechnology and Bioengineering, vol.89, issue.Suppl. 1, pp.481-494, 1996.
DOI : 10.1007/978-1-4684-0772-3

E. Szoke, N. N. Dung, G. Verzar-petri, and A. Potoczki, Change in the total alkaloid contents in the tissue cultures of Datura innoxia Mill, the function of the cultural circumstances, pp.3-4, 1982.

T. Takeda, M. Inomata, H. Matsuoka, M. Hikuma, and S. Furusaki, Release of anthocyanin from strawberry cultured cells with heating treatment, Biochemical Engineering Journal, vol.15, issue.3, pp.205-210, 2003.
DOI : 10.1016/S1369-703X(02)00213-9

R. Teglberg and R. Et-julkumen-tiitto, Quantitative changes in secondary metabolites of dark-leaved willow (Salix myrsinifolia) exposed to enhanced ultraviolet-B radiation, Physiologia Plantarum, vol.115, issue.4, pp.541-547, 2001.
DOI : 10.1104/pp.115.4.1405

J. Tempé and A. Goldmann, Occurrence and biosynthesis of opines Molecular biology of plant tumors, pp.428-449, 1982.

D. Tepfer and J. Tempé, Production d'agropine par des raciness formées sous l'action d'Agrobacterium rhizogenes, souches A4, C. R. Acad. Sci, vol.292, pp.153-156, 1991.

R. Thimmaraju, N. Bhagyalakshmi, M. S. Narayan, and G. A. Ravishankar, Kinetics of pigment release from hairy root cultures of Beta vulgaris under the influence of pH, sonication, temperature and oxygen stress, Process Biochemistry, vol.38, issue.7, pp.1069-1076, 2003.
DOI : 10.1016/S0032-9592(02)00234-0

J. A. Tindall, H. A. Mills, and D. E. Radcliffe, The effect of root zone temperature on nutrient uptake of tomato, Journal of Plant Nutrition, vol.9, issue.8, pp.939-956, 1990.
DOI : 10.2307/2528076

T. L. Tran, T. D. Vu, B. Mignard, F. Biteau, J. P. Fèvre et al., Hydroponics as a model technology for producing plant root secondary metabolites, Biotechnology in Agriculture, pp.20-21, 2006.

T. L. Tran, Synthèse et accumulation d'alcaloïdes tropaniques chez Datura innoxia Mill. cultivé en hydroponie : analyse des effets de l'environnement biotique et abiotique ; essais de mise en place d'une nouvelle technologie de production, Thèse de doctorat, Institut National Polytechnique de Lorraine en Sciences Agronomiques, 2005.

V. Van-de-velde and H. , Hyoscyamine and scopolamine production in Datura stramonium var. Tatuala, Acta Agronomica Hungarica, vol.37, pp.51-63, 1988.

A. Van-der-werf, M. Van-nuenen, A. J. Visser, and H. Lambers, Effects of N-supply on the rates of photosynthesis and shoot and root respiration of inherently fast- and slow-growing monocotyledonous species, Physiologia Plantarum, vol.7, issue.3, pp.563-569, 1993.
DOI : 10.1007/BF00384257

G. Vancannyet, R. Schmidt, A. O-'connor-sanchez, L. Willmitzer, and . Rocha-sosa, Construction of an intron-containing marker gene: Splicing of the intron in transgenic plants and its use in monitoring early events in Agrobacterium-mediated plant transformation, MGG Molecular & General Genetics, vol.220, issue.2, 1990.
DOI : 10.1007/BF00260489

A. Vasconsuelo, A. M. Giulietti, and R. Boland, Signal transduction events mediating chitosan stimulation of anthraquinone synthesis in Rubia tinctorum, Plant Science, vol.166, issue.2, pp.405-413, 2004.
DOI : 10.1016/j.plantsci.2003.10.007

V. Veena and C. G. Taylor, Agrobacterium rhizogenes: recent developments and promising applications, In Vitro Cellular & Developmental Biology - Plant, vol.93, issue.Suppl, pp.383-403, 2007.
DOI : 10.17660/ActaHortic.2000.521.15

K. Veluthambi, M. Krishnan, J. H. Gould, R. H. Smith, and S. B. Gelvin, Opines stimulate induction of the vir genes of the Agrobacterium tumefaciens Ti plasmid., Journal of Bacteriology, vol.171, issue.7, pp.3696-3703, 1989.
DOI : 10.1128/jb.171.7.3696-3703.1989

R. Verpoorte, Pharmacognosy in the New Millennium: Leadfinding and Biotechnology, Journal of Pharmacy and Pharmacology, vol.30, issue.3, pp.253-262, 2000.
DOI : 10.1016/0031-9422(91)83424-J

R. Verpoorte, R. Van-der-heijden, H. J. Ten-hoopen, and J. Memelink, Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals, Biotechnology Letters, vol.21, issue.6, pp.467-479, 1999.
DOI : 10.1023/A:1005502632053

R. Verpoorte, R. Van-der-heijden, W. M. Van-gulik, and H. J. , Plant biotechnology for the production of alkaloids: present status and prospects, pp.1-187, 1991.

V. Petri and G. , Histochemical and historadigraphic examination of alkaloid localization in the vegetative organs of Datura innoxia Mill, Acta Botanica Academiae Scientiarum Hungaricae, vol.18, pp.257-271, 1973.

V. Petri, G. Huynh, and D. , Formation of the alkaloid content and composition of Datura innoxia Mill. during sprouting, Acta Pharmaceutica Hungarica, vol.47, pp.37-44, 1977.

S. Z. Viña, D. F. Olivera, C. M. Marani, R. M. Ferreyra, A. Mugridge et al., Quality of Brussels sprouts (Brassica oleracea L. gemmifera DC) as affected by blanching method, Journal of Food Engineering, vol.80, issue.1, pp.218-225, 2007.
DOI : 10.1016/j.jfoodeng.2006.02.049

T. D. Vu, T. L. Tran, B. Mignard, F. Biteau, H. S. Hassani et al., Modélisation de la croissance et de la production d'alcaloïdes tropaniques de Datura innoxia Mill. cultivé en hydroponie ; évaluation de l'effet de l'intensité d'éclairement sur le développement de la plante et la biosynthèse d'hyoscyamine et de scopolamine, pp.2-9518564, 2006.

T. D. Vu, T. L. Tran, F. Biteau, B. Mignard, J. P. Fèvre et al., Improvement of secondary metabolites production in hydroponic cultures by Mechanical and biological processes, Biotechnology in Agriculture, pp.20-21, 2006.

T. D. Vu, Effet de la disponibilité en nitrate de la solution nutritive sur la croissance et le statut azoté du Choysum (Brassica rapa var Choysum) Mémoire de DEA en Sciences Agronomique, p.25, 2003.

G. P. Waller and E. R. Nowacki, Alkaloid biology and metabolisme in plants, 1978.

Y. C. Wang, H. X. Zhang, B. Zhao, and X. F. Yuan, Improved growth of Artemisia annua L. hairy root and artemisinin production under red light conditions, Biotechnology Letters, vol.23, issue.23, pp.1971-1973, 2001.
DOI : 10.1023/A:1013786332363

R. O. Wijrsekera, The Medicinal plant industry Inc. ISBN 0-8493- 6669-0, 269p. 233 Modes of action of alkaloids In: Alkaloids : Biochemistry, ecology and medicinal applications, Wink M, pp.301-326, 1991.

M. Wink and L. Witte, Turnover and transport of quinolizidine alkaloids. Diurnal fluctuations of lupanine in the phloem sap, leaves and fruits of Lupinus albus L., Planta, vol.23, issue.6, pp.519-521, 1994.
DOI : 10.1016/S0044-328X(81)80205-X

J. Wu, L. Lin, and F. T. Chau, Ultrasound-assisted extraction of ginseng saponins from ginseng roots and cultured ginseng cells, Ultrasonics Sonochemistry, vol.8, issue.4, pp.347-352, 2001.
DOI : 10.1016/S1350-4177(01)00066-9

Y. Yamada and Y. Fujita, Production of useful compounds from culture In: Handbook of Plant Cell Culture, pp.717-728, 1986.

Y. Yankoulov, Morphogenetic alkaloid concentration variability in tetraploid thornapple, Genetics and Plant Breeding, vol.12, issue.6, pp.416-422, 1979.

Z. Zabetakis, I. Edwards, R. Et-o-'hagan, and D. , Elicitation of tropane alkaloid biosynthesis in transformed root cultures of Datura stramonium, Phytochemistry, vol.50, issue.1, pp.53-56, 1999.
DOI : 10.1016/S0031-9422(98)00490-7

P. Zambryski, Chronicles from the Agrobacterium-Plant Cell DNA Transfer Story, Annual Review of Plant Physiology and Plant Molecular Biology, vol.43, issue.1, 1992.
DOI : 10.1146/annurev.pp.43.060192.002341

P. C. Zambryski, J. Tempe, and J. Schell, Transfer and function of T-DNA genes from Agrobacterium Ti and Ri plasmids in plants, Cell, vol.56, issue.2, pp.193-201, 1989.
DOI : 10.1016/0092-8674(89)90892-1

M. Zehra, S. Banerjee, A. A. Naqvi, and S. Kumar, Variation in the growth and alkaloid production capability of the hairy roots of Hyoscyamus albus, H. muticus and their somatic hybrid, Plant Science, vol.136, issue.1, pp.93-99, 1998.
DOI : 10.1016/S0168-9452(98)00091-0

J. Zhao, W. H. Zhu, Q. Hu, and Y. Q. Et-guo, Improvement of indole alkaloid production in Catharanthus roseus cell cultures by osmotic shock, Biotechnology Letters, vol.22, issue.15, pp.1227-1231, 2000.
DOI : 10.1023/A:1005653113794

A. M. Zobel and S. A. Brown, Dermatitis-inducing furanocoumarins on leaf surfaces of eight species of Rutaceous and Umbelliferous plants, Journal of Chemical Ecology, vol.67, issue.3, pp.693-700, 1990.
DOI : 10.1007/BF01016480

A. M. Zobel and S. A. Brown, Determination of Furanocoumarins on the Leaf Surface of Ruta graveolens with an Improved Extraction Technique, Journal of Natural Products, vol.51, issue.5, pp.941-946, 1988.
DOI : 10.1021/np50059a021

A. M. Zobel and S. A. Brown, shoots, Canadian Journal of Botany, vol.67, issue.3, pp.915-921, 1988.
DOI : 10.1139/b89-120

P. Planche and 7. , Germination de graines de Datura innoxia sur milieu gélosé depuis un mois

P. Planche, Germination de graines de Datura innoxia sur les cubes de laine de roche (a)Planche et sur du mélange sable/terreau (b) depuis 3 semaines

P. Planche, Dispositif développé dans cette thèse pour la réalisation de culture hydroponique stérile (à gauche) et une culture individuelle de datura bien fermée depuis 4 semaines

P. Planche, Racines de Datura innoxia en culture hydroponique dans le système pilote. (source d'équipe)