Skip to Main content Skip to Navigation
Theses

Élaboration de copolymères biorésorbables pour endoprothèse

Abstract : This work describes the synthesis of biodegradable copolymer to design a bioabsorbable endoprosthesis. Lactide and glycolide-based copolymers were synthesized by ring opening polymerization. Experimental conditions were chosen to produce controlled structures. The study of mechanical properties was performed in dry and wet states. During the tensile experiments, the effect of strain rate was noticed and some characteristics parameters were determined. Hydrolytic degradation of materials was fast and revealed a heterogeneous mechanism. Addition of acidic molecules for plasticizing increased the degradation rate of the copolymers.Mechanical properties and degradation of the PDLGA copolymers are indeed in good agreement with the specifications of this biomedical application.
Document type :
Theses
Complete list of metadata

https://hal.univ-lorraine.fr/tel-01754519
Contributor : Thèses Ul Connect in order to contact the contributor
Submitted on : Friday, July 23, 2021 - 10:27:24 AM
Last modification on : Friday, July 23, 2021 - 10:29:16 AM
Long-term archiving on: : Sunday, October 24, 2021 - 6:15:34 PM

File

INPL_T_2011_DUVAL_C.pdf
Files produced by the author(s)

Identifiers

  • HAL Id : tel-01754519, version 1

Collections

Citation

Charlotte Duval. Élaboration de copolymères biorésorbables pour endoprothèse. Autre. Institut National Polytechnique de Lorraine, 2011. Français. ⟨NNT : 2011INPL018N⟩. ⟨tel-01754519⟩

Share

Metrics

Record views

83

Files downloads

34