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M. , F. 8. Godard, P. Aubas, P. Vic, and P. , Poumon, mirolr des mokrdies krtrogènes. L'exemple de l'omiodorone. tull. Acod. l'tqile Méd., -LZq I ), pp.57-69

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E. , MedsiPoris (t986) 2l-ANDREASEN, F. et co[., Eur, J. Clin. Phormoc.,-19, p.3

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, Blbllogrophle r99

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, Blbliogrophie ANNEXES ANNEXE, vol.1

S. Del-'amiodarone, , p.4

, Benzène Bromure de méthoxY, p.4

, Phényl Magnésium

, HCr n-Butyl-2 Benzofurane (3N) Benzène anhydre Chlorure Stannique KOH EAU t 1Kl+l 2 ) dans eau Acide MéthoxY-4

, Rendt : 59 %) to"rr j, Benzoîque

. Lg,

, Chlorure de méthoxy-4

, (méthoxY'4' Benzoyl)-3 Benzolurane lCnlorhVdrate { Pyridine co Hg n-Butyl-2(hyd roxY-4' Benzoyl)-3 Benzofurane n-Butyl-2(Diiodo-3',5' Hydroxy-4' Benzoyl)-3

, Benzotura ne 1")EIOCOOEI /Benzène 2') crcH2CH2N(Et)

, HCI (d'après document SANOFI

A. , C. Des, . Lamma, . Avec, and . References, La calibration des spectres se déroule de façon différente si le temps "zéro" (instant où I'impulsion laser est déclenchée)

, On assimile le temps que met I'ion à parcourir le tube à 'la longueur parcourue. \o1.; =L tror"t =c

L. and =. C. , Puisque le temps zéro est connu : C' = 0 d'où L = Cr (m;trz Pour calibrer, les éléments alcalins sont souvent utilisés comme masses références : par exemple, pour

, ou 39 et le pic de masse inconnue à la distance L, s'écrit C, (m*)1t2 aVeC L 1 : distance entre le point zéro et le signal de I'ion de masse Connue m1, p.39

, * : distance entre le point zéro et le signal de l'ion de masse inconnue my La constante C2 est égale à : LL C=l -26J\ D'où

, Si tous les paramètres instrumentaux et les potentiels d'extraction des ions restent fixés pendant la série d'analyses, le rapport m, est constant (C) et connu. On écrit alors : ffix= C.\t ffi, = _,[il