M. C. Chiti, M. M. Dolmans, J. Donnez, and C. A. Amorim, Fibrin in Reproductive Tissue Engineering: A Review on Its Application as a Biomaterial for Fertility Preservation, vol.45, pp.1650-1663, 2017.

M. Mousa, N. D. Evans, R. O. Oreffo, and J. I. Dawson, « Clay nanoparticles for regenerative medicine and biomaterial design: A review of clay bioactivity, Biomaterials, vol.159, pp.204-214, 2018.

M. T. Calejo, T. Ilmarinen, H. Skottman, and M. Kellomäki, « Breath figures in tissue engineering and drug delivery: State-of-the-art and future perspectives, Acta Biomater, vol.66, pp.44-66, 2018.

H. W. Ooi, S. Hafeez, C. A. Van-blitterswijk, L. Moroni, and M. B. Baker, Hydrogels that listen to cells: a review of cell-responsive strategies in biomaterial design for tissue regeneration, vol.4, pp.1020-1040, 2017.

C. Merceron, C. Vinatier, J. Clouet, S. Colliec-jouault, P. Weiss et al., Cellules souches mésenchymateuses du tissu adipeux et biomatériaux pour l'ingénierie tissulaire du cartilage, vol.75, pp.942-944, 2008.

J. Dubernard, Outcomes 18 Months after the First Human Partial Face Transplantation, vol.357, pp.2451-2460, 2007.
URL : https://hal.archives-ouvertes.fr/hal-01980953

L. Lantieri, « Repair of the lower and middle parts of the face by composite tissue allotransplantation in a patient with massive plexiform neurofibroma: a 1-year followup study, The Lancet, vol.372, pp.639-645, 2008.

S. Gaujoux, J. Larghero, and P. Cattan, « L'ingénierie tissulaire, bientôt une solution au remplacement d'organe ?, J. Chir, vol.146, issue.2, pp.109-111, 2009.

T. Poghosyan, S. Gaujoux, R. Sfeir, J. Larghero, and P. Cattan, « Bioartificial Oesophagus in the Era of Tissue Engineering, vol.52, pp.16-17, 2011.

R. Langer and J. Vacanti, « Tissue engineering, vol.260, pp.920-926, 1993.

T. Poghosyan, « L'ingénierie tissulaire de l'oesophage : états des lieux et perspectives, J. Chir. Viscérale, vol.153, issue.1, pp.21-30, 2016.

, Développement de procédés additifs pour des applications en ingénierie tissulaire osseuse, pp.30-2016

A. Erices, P. Conget, and J. J. Minguell, « Mesenchymal progenitor cells in human umbilical cord blood, Br. J. Haematol, vol.109, issue.1, pp.235-242, 2000.

L. Galois, A. Freyria, D. Herbage, and D. Mainard, Ingénierie tissulaire du cartilage : état des lieux et perspectives », vol.53, pp.590-598, 2005.

P. Hardouin, K. Anselme, B. Flautre, F. Bianchi, G. Bascoulergue et al.,

. «-ingénierie-tissulaire, Rev. Rhum, vol.67, issue.7, pp.498-504, 2000.

A. Atala, S. B. Bauer, S. Soker, J. J. Yoo, and A. B. Retik, « Tissue-engineered autologous bladders for patients needing cystoplasty, The Lancet, vol.367, pp.1241-1246, 2006.

P. Macchiarini, « Clinical transplantation of a tissue-engineered airway, The Lancet, vol.372, pp.2023-2030, 2008.

J. P. Vacanti and R. Langer, « Tissue engineering: the design and fabrication of living replacement devices for surgical reconstruction and transplantation, The Lancet, vol.354, pp.32-34, 1999.

E. Lavik and R. Langer, « Tissue engineering: current state and perspectives

, Microbiol. Biotechnol, vol.65, issue.1, 2004.

R. N. Bhandari, « Liver Tissue Engineering: A Role for Co-culture Systems in Modifying Hepatocyte Function and Viability, Tissue Eng, vol.7, issue.3, pp.345-357, 2001.

S. Macneil, Progress and opportunities for tissue-engineered skin, Nature, vol.445, pp.874-880, 2007.

A. C. Macintosh, V. R. Kearns, A. Crawford, and P. V. Hatton, « Skeletal tissue engineering using silk biomaterials, J. Tissue Eng. Regen. Med, vol.2, pp.71-80, 2008.

X. Hu, W. Lui, L. Cui, M. Wang, and Y. Cao, Tissue Engineering of Nearly Transparent Corneal Stroma, vol.11, pp.1710-1717, 2005.

S. Rimmer, « Epithelialization of hydrogels achieved by amine functionalization and co-culture with stromal cells, Biomaterials, vol.28, pp.5319-5331, 2007.

T. Matikainen and J. Laine, « Placenta-an alternative source of stem cells

, Appl. Pharmacol, vol.207, issue.2, pp.544-549, 2005.

Y. Miyahara, « Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction, Nat. Med, vol.12, issue.4, pp.459-465, 2006.

D. Dallari, Enhanced Tibial Osteotomy Healing with Use of Bone Grafts Supplemented with Platelet Gel or Platelet Gel and Bone Marrow Stromal Cells, J. Bone Jt

, Surg. Am, vol.89, issue.11, p.2413, 2007.

A. Nieponice, Patch Esophagoplasty: Esophageal Reconstruction Using Biologic Scaffolds, vol.97, pp.283-288, 2014.

J. Huxley-jones, S. M. Foord, and M. R. Barnes, « Drug discovery in the extracellular matrix, Drug Discov. Today, vol.13, pp.685-694, 2008.

J. Labat-robert and L. Robert, « Introduction: matrix biology in the 21st century. From a static-rheological role to a dynamic-signaling function, Pathol. Biol, vol.53, issue.7, pp.369-371, 2005.

C. Jaeger, P. Cherin, ». Matrice, and M. Longévité, , vol.4, pp.41-53, 2012.

B. C. Isenberg and J. Y. Wong, Building structure into engineered tissues », Mater. Today, vol.9, pp.54-60, 2006.

F. Ramirez, L. Y. Sakai, H. C. Dietz, and D. B. Rifkin, « Fibrillin microfibrils: multipurpose extracellular networks in organismal physiology, Physiol. Genomics, vol.19, issue.2, pp.151-154, 2004.

A. Bailey, « Molecular mechanisms of ageing in connective tissues, Mech. Ageing Dev, vol.122, issue.7, pp.735-755, 2001.

S. P. Sugrue, Response of basal epithelial cell surface and Cytoskeleton to solubilized extracellular matrix molecules, J. Cell Biol, vol.91, issue.1, pp.45-54, 1981.

J. Labat-robert, M. Bihari-varga, and E. L. Robert, « Extracellular matrix, vol.268, issue.2, pp.386-393, 1990.

A. Naba, S. Hoersch, and R. O. Hynes, « Towards definition of an ECM parts list: An advance on GO categories, Matrix Biol, vol.31, pp.371-372, 2012.

S. Ricard-blum, The Collagen Family, vol.3, pp.4978-004978, 2011.

H. Lodish, A. Berk, and S. L. Zipursky, Molecular Cell Biology, 2000.

R. S. Jope and G. V. ,

J. , The glamour and gloom of glycogen synthase kinase

, Trends Biochem. Sci, vol.29, issue.2, pp.95-102, 2004.

G. V. Rayasam, V. K. Tulasi, R. Sodhi, J. A. Davis, and E. A. Ray, Glycogen synthase kinase 3: more than a namesake: GSK3: a therapeutic target for diabetes, vol.156, pp.885-898, 2009.

K. R. , « Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling, Cell, vol.139, issue.5, pp.891-906, 2009.

L. Goldman and . Ausiello, Cecil medicine, vol.702, 2008.

P. A. Philadelphia^-epa,

V. Stambolic and J. R. Woodgett, Mitogen inactivation of glycogen synthase, p.3
DOI : 10.1042/bj3030701

, Biochem. J, vol.303, issue.3, pp.701-704, 1994.

L. M. Shaw and B. R. Olsen, « FACIT collagens: diverse molecular bridges in extracellular matrices, Trends Biochem. Sci, vol.16, pp.191-194, 1991.
DOI : 10.1016/0968-0004(91)90074-6

A. K. Baldwin, A. Simpson, R. Steer, S. A. Cain, and C. M. Kielty, « Elastic fibres in health and disease, Expert Rev. Mol. Med, vol.15, 2013.

D. Y. Li, « Elastin is an essential determinant of arterial morphogenesis, Nature, vol.393, pp.276-280, 1998.
DOI : 10.1038/30522

R. Bascetin, Etude de l'auto-assemblage de la fibronectine plasmatique humaine: mécanismes et réponses cellulaires (Doctoral dissertation, 2014.

R. V. Iozzo and «. Matrix-proteoglycans, From Molecular Design to Cellular Function, Annu. Rev. Biochem, vol.67, issue.1, pp.609-652, 1998.
DOI : 10.1146/annurev.biochem.67.1.609

N. S. Gandhi and R. L. Mancera, The Structure of Glycosaminoglycans and their Interactions with Proteins, vol.72, pp.455-482, 2008.

S. Kim, J. Turnbull, and E. S. Guimond, « Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor, J. Endocrinol, vol.209, issue.2, pp.139-151, 2011.

R. O. Hynes and A. Naba, « Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions, Cold Spring Harb. Perspect. Biol, vol.4, issue.1, pp.4903-004903

R. Qian and R. W. Glanville, Alignment of Fibrillin Molecules in Elastic Microfibrils Is Defined by Transglutaminase-Derived Cross-Links », vol.36, pp.15841-15847, 1997.

M. Bignon, « Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane, Blood, vol.118, pp.3979-3989, 2011.

M. «-1st, Matrix Biology Europe) conference », 2014.

R. Zent, A. Pozzi, and É. , Cell-Extracellular Matrix Interactions in Cancer, 2010.

I. D. Campbell and M. J. Humphries, « Integrin Structure

. Interactions, Cold Spring Harb. Perspect. Biol, vol.3, issue.3, pp.4994-004994, 2011.

M. Leiss, K. Beckmann, A. Girós, M. Costell, and R. Fässler, The role of integrin binding sites in fibronectin matrix assembly in vivo, vol.20, pp.502-507, 2008.

R. O. Hynes, « Integrins: Bidirectional, allosteric signaling machines, vol.110, pp.673-687, 2002.

N. M. Alves, I. Pashkuleva, R. L. Reis, and J. F. Mano, Controlling Cell Behavior Through the Design of Polymer Surfaces, vol.6, pp.2208-2220, 2010.

R. Zaidel-bar, S. Itzkovitz, A. Ma'ayan, R. Iyengar, and B. Geiger, « Functional atlas of the integrin adhesome, Nat. Cell Biol, vol.9, issue.8, pp.858-867, 2007.

B. Geiger, A. Bershadsky, R. Pankov, and K. M. Yamada, « Transmembrane crosstalk between the extracellular matrix and the cytoskeleton », Nat. Rev. Mol. Cell Biol, vol.2, issue.11, pp.793-805, 2001.

M. J. Biggs and M. J. Dalby, « Focal adhesions in osteoneogenesis, Proc. Inst. Mech. Eng, vol.224, pp.1441-1453

T. Geiger and R. Zaidel-bar, Opening the floodgates: proteomics and the integrin adhesome, vol.24, pp.562-568, 2012.

T. N. Wight, Versican: a versatile extracellular matrix proteoglycan in cell biology, Curr. Opin. Cell Biol, vol.14, issue.5, pp.617-623, 2002.

R. Pankov, « Fibronectin at a glance, J. Cell Sci, vol.115, pp.3861-3863, 2002.

E. A. Verderio, T. Johnson, and M. Griffin, « Tissue transglutaminase in normal and abnormal wound healing: Review article, Amino Acids, vol.26, 2004.

A. Rey, Les cellules souches sont-elles bien nommées ? », médecine/sciences, vol.19, pp.645-645, 2003.

T. «-margossian, Caractérisation des Cellules Souches Mésenchymateuses du sang placentaire et de la gelée de Wharton (Doctoral dissertation, 2013.

C. Martinaud, « Les cellules souches mésenchymateuses : des cellules pour la médecine régénérative du futur ?, Rev. Francoph. Lab, vol.2010, pp.47-59

M. Owen, « Marrow stromal stem cells, J. Cell Sci, vol.1988, pp.63-76, 1988.

A. I. Caplan, « Mesenchymal stem cells, J. Orthop. Res, vol.9, issue.5, pp.641-650, 1991.

M. Dominici, « Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement, Cytotherapy, vol.8, issue.4, pp.315-317, 2006.

C. «-roubeix, Intérêt des cellules souches mésenchymateuses dans la thérapie du glaucome (Doctoral dissertation, 2014.

M. Krampera, J. Galipeau, Y. Shi, K. Tarte, and L. Sensebe, « Immunological characterization of multipotent mesenchymal stromal cells-The International Society for Cellular Therapy (ISCT) working proposal, Cytotherapy, vol.15, issue.9, pp.1054-1061, 2013.

L. Da-silva-meirelles, « Mesenchymal stem cells reside in virtually all post-natal organs and tissues, J. Cell Sci, vol.119, issue.11, pp.2204-2213, 2006.

D. T. Covas, « Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and fibroblasts, Exp. Hematol, vol.36, issue.5, pp.642-654, 2008.

S. Kern, H. Eichler, J. Stoeve, H. Klüter, and K. Bieback, Comparative Analysis

, Umbilical Cord Blood, or Adipose Tissue, Stem Cells, vol.24, issue.5, pp.1294-1301, 2006.

H. Yu, Évaluation des caractéristiques des hydrogels d'alginate supplémentés en acide hyaluronique ou en hydroxyapatite lors de la différenciation des cellules souches mésenchymateuses issues de la gelée de Wharton (Doctoral dissertation, 2017.

M. F. Pittenger, « Multilineage Potential of Adult Human Mesenchymal Stem Cells », Science, vol.284, issue.5411, pp.143-147, 1999.

H. Yoshimura, T. Muneta, A. Nimura, A. Yokoyama, H. Koga et al., « Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle », Cell Tissue Res, vol.327, issue.3, pp.449-462, 2007.

B. A. Bunnell, B. T. Estes, F. Guilak, and J. M. Gimble, Adipose Tissue Protocols, vol.456, pp.155-171, 2008.

W. J. Jurgens, « Effect of tissue-harvesting site on yield of stem cells derived from adipose tissue: implications for cell-based therapies, Cell Tissue Res, vol.332, issue.3, pp.415-426, 2008.

C. Y. Tay, P. Sathiyanathan, S. W. Chu, L. W. Stanton, and T. T. Wong,

, Trabecular Meshwork of the Human Eye, vol.21, issue.9, pp.1381-1390

L. J. Bray, C. F. Heazlewood, D. J. Munster, D. W. Hutmacher, K. Atkinson et al.,

. Harkin, Immunosuppressive properties of mesenchymal stromal cell cultures derived from the limbus of human and rabbit corneas, vol.16, pp.64-73, 2014.

F. Rossignoli, « Isolation, Characterization, and Transduction of Endometrial Decidual Tissue Multipotent Mesenchymal Stromal/Stem Cells from Menstrual Blood, BioMed Res. Int, vol.2013, pp.1-14, 2013.

O. G. Davies, P. R. Cooper, R. M. Shelton, A. J. Smith, and B. A. Scheven, « A comparison of the in vitro mineralisation and dentinogenic potential of mesenchymal stem cells derived from adipose tissue, bone marrow and dental pulp, J. Bone Miner. Metab, vol.33, issue.4, pp.371-382, 2015.

M. Crisan, « A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs, Cell Stem Cell, vol.3, issue.3, pp.301-313, 2008.

R. Liao, O. Pfister, M. Jain, and F. Mouquet,

, Myocardial Regeneration », vol.50, issue.1, pp.18-30, 2007.

T. Asahara, C. Kalka, and J. , Isner, « Stem cell therapy and gene transfer for regeneration, Gene Ther, vol.7, pp.451-457, 2000.

E. L. Herzog, « Plasticity of marrow-derived stem cells, Blood, vol.102, issue.10, pp.3483-3493, 2003.

F. Ulloa-montoya, C. M. Verfaillie, and W. Hu, « Culture systems for pluripotent stem cells, J. Biosci. Bioeng, vol.100, issue.1, pp.12-27, 2005.

L. Li, T. Xie, «. Stem, and . Niche, Structure and Function, vol.21, pp.605-631, 2005.
URL : https://hal.archives-ouvertes.fr/in2p3-00013988

D. L. Jones and A. J. Wagers, « No place like home: anatomy and function of the stem cell niche, Nat. Rev. Mol. Cell Biol, vol.9, issue.1, pp.11-21, 2008.

Y. Katayama, « Signals from the Sympathetic Nervous System Regulate Hematopoietic Stem Cell Egress from Bone Marrow, Cell, vol.124, issue.2, pp.407-421, 2006.

U. Nekanti, V. B. Rao, A. G. Bahirvani, M. Jan, S. Totey et al., « Long-Term Expansion and Pluripotent Marker Array Analysis of Wharton's Jelly-Derived Mesenchymal Stem Cells, Stem Cells Dev, vol.19, issue.1, pp.117-130, 2010.

S. Méndez-ferrer, « Mesenchymal and haematopoietic stem cells form a unique bone marrow niche, Nature, vol.466, pp.829-834, 2010.

C. Shi and E. G. Pamer, « Monocyte recruitment during infection and inflammation, Nat. Rev. Immunol, vol.11, issue.11, pp.762-774, 2011.
DOI : 10.1038/nri3070

URL : http://europepmc.org/articles/pmc3947780?pdf=render

C. M. Schürch, C. Riether, and A. F. Ochsenbein, Cytotoxic CD8+ T Cells Stimulate Hematopoietic Progenitors by Promoting Cytokine Release from Bone Marrow

, Mesenchymal Stromal Cells, vol.14, pp.460-472, 2014.

C. Shi, Bone Marrow Mesenchymal Stem and Progenitor Cells Induce

. Monocyte, Response to Circulating Toll-like Receptor Ligands », Immunity, vol.34, pp.590-601, 2011.

A. Rodriguez, « Transplantation of a multipotent cell population from human adipose tissue induces dystrophin expression in the immunocompetent mdx mouse, J. Exp. Med, vol.201, issue.9, pp.1397-1405, 2005.

L. Song and R. S. Tuan, « Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow, FASEB J, vol.18, issue.9, pp.980-982, 2004.

K. Mareschi, « Neural differentiation of human mesenchymal stem cells: evidence for expression of neural markers and eag K+ channel types, Exp. Hematol, vol.34, issue.11, pp.1563-1572, 2006.

M. L. Khoo, B. Shen, H. Tao, and D. D. Ma, « Long-Term Serial Passage and Neuronal Differentiation Capability of Human Bone Marrow Mesenchymal Stem Cells, Stem Cells Dev, vol.17, issue.5, pp.883-896, 2008.

P. Antonitsis, E. Ioannidou-papagiannaki, A. Kaidoglou, and C. Papakonstantinou, « In vitro cardiomyogenic differentiation of adult human bone marrow mesenchymal stem cells

, The role of 5-azacytidine », vol.6, pp.593-597, 2007.

S. Shu, Hepatic differentiation capability of rat bone marrow-derived mesenchymal stem cells and hematopoietic stem cells », World J. Gastroenterol, vol.10, p.2818, 2004.

L. Chen, « Differentiation of rat marrow mesenchymal stem cells into pancreatic islet beta-cells », World J. Gastroenterol, vol.10, p.3016, 2004.
DOI : 10.3748/wjg.v10.i20.3016

URL : https://doi.org/10.3748/wjg.v10.i20.3016

H. Aslan, Osteogenic Differentiation of Noncultured Immunoisolated Bone Marrow-Derived CD105 + Cells, vol.24, pp.1728-1737, 2006.
DOI : 10.1634/stemcells.2005-0546

B. Johnstone, T. M. Hering, A. I. Caplan, V. M. Goldberg, and J. U. Yoo, VitroChondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells, vol.238, pp.265-272, 1998.
DOI : 10.1006/excr.1997.3858

R. G. Young, D. L. Butler, W. Weber, A. I. Caplan, S. L. Gordon et al., Use of mesenchymal stem cells in a collagen matrix for achilles tendon repair, J. Orthop. Res, vol.16, issue.4, pp.406-413, 1998.

P. E. Westerweel and M. C. Verhaar, « Directing Myogenic Mesenchymal Stem Cell Differentiation », Circ. Res, vol.103, issue.6, pp.560-561, 2008.
DOI : 10.1161/circresaha.108.184374

S. P. Bruder, N. Jaiswal, and S. E. Haynesworth, « Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation, J. Cell. Biochem, vol.64, issue.2, pp.278-294, 1997.

B. Sacchetti, « Self-Renewing Osteoprogenitors in Bone Marrow Sinusoids Can Organize a Hematopoietic Microenvironment, Cell, vol.131, issue.2, pp.324-336, 2007.

U. Lakshmipathy and C. Verfaillie, « Stem cell plasticity, Blood Rev, vol.19, issue.1, pp.29-38, 2005.

B. Chelluboina, D. H. Dinh, and K. K. Veeravalli, « Transdifferentiation of differentiated stem cells contributes to remyelination, Stem Cell Res. Ther, vol.6, issue.1, 2015.

M. Pokrywczynska, « Transdifferentiation of Bone Marrow Mesenchymal Stem Cells into the Islet-Like Cells: the Role of Extracellular Matrix Proteins

, Ther. Exp. (Warsz.), vol.63, issue.5, pp.377-384, 2015.

L. Song and R. S. Tuan, « Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow, FASEB J, vol.18, issue.9, pp.980-982, 2004.

V. Fitzpatrick, Micro-impression de BMP-2 et fibronectine sur des matériaux mous: un outil pour recréer la niche de cellules souches in vitro (Doctoral dissertation, 2017.

A. Mantovani, M. Mscs, and C. , Cell Stem Cell, vol.11, issue.6, pp.730-732

L. Chen, E. E. Tredget, P. Y. Wu, and Y. Wu, Paracrine Factors of Mesenchymal Stem Cells Recruit Macrophages and Endothelial Lineage Cells and Enhance Wound Healing, vol.3, 2008.

S. H. Mei, « Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis, Am. J. Respir. Crit. Care Med, vol.182, issue.8, pp.1047-1057, 2010.
DOI : 10.1164/rccm.201001-0010oc

K. Németh, « Bone marrow stromal cells attenuate sepsis via prostaglandin E2-dependent reprogramming of host macrophages to increase their interleukin-10 production, Nat. Med, vol.15, issue.1, pp.42-49, 2009.

M. Krampera, Mesenchymal stromal cell ?licensing': a multistep process, vol.25, pp.1408-1414, 2011.
DOI : 10.1038/leu.2011.108

URL : https://www.nature.com/articles/leu2011108.pdf

R. S. Waterman, S. L. Tomchuck, S. L. Henkle, and A. M. Betancourt, A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an
DOI : 10.1371/journal.pone.0010088

URL : https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0010088&type=printable

. Immunosuppressive-msc2-phenotype, PLoS ONE, vol.5, 2010.

J. L. Chan, Antigen-presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-?, Blood, vol.107, pp.4817-4824, 2006.

R. Ramasamy, C. K. Tong, H. F. Seow, S. Vidyadaran, and F. Dazzi, « The immunosuppressive effects of human bone marrow-derived mesenchymal stem cells target T cell proliferation but not its effector function, Cell. Immunol, vol.251, issue.2, pp.131-136, 2008.

R. Meisel, « Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation, Blood, vol.103, pp.4619-4621, 2004.
DOI : 10.1182/blood-2003-11-3909

URL : http://www.bloodjournal.org/content/103/12/4619.full.pdf

C. Menard, « Clinical-Grade Mesenchymal Stromal Cells Produced Under Various Good Manufacturing Practice Processes Differ in Their Immunomodulatory Properties: Standardization of Immune Quality Controls, Stem Cells Dev, vol.22, pp.1789-1801, 2013.

G. Ren, « Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide, Cell Stem Cell, vol.2, issue.2, pp.141-150, 2008.

R. H. Lee, « Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6 », Cell Stem Cell, vol.5, issue.1, pp.54-63, 2009.

S. , « Human mesenchymal stem cells modulate allogeneic immune cell responses, Blood, vol.105, issue.4, pp.1815-1822, 2005.

H. Choi, R. H. Lee, N. Bazhanov, J. Y. Oh, and D. J. Prockop, « Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-B signaling in resident macrophages, Blood, vol.118, issue.2, pp.330-338, 2011.

M. and D. Nicola, Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli, Blood, vol.99, issue.10, pp.3838-3843, 2002.

O. Delarosa and E. Lombardo, Modulation of Adult Mesenchymal Stem Cells Activity by Toll-Like Receptors: Implications on Therapeutic Potential, vol.2010, pp.1-9, 2010.

Y. Shi, J. Su, A. I. Roberts, P. Shou, A. B. Rabson et al., « How mesenchymal stem cells interact with tissue immune responses, Trends Immunol, vol.33, issue.3, pp.136-143, 2012.
DOI : 10.1016/j.it.2011.11.004

URL : http://europepmc.org/articles/pmc3412175?pdf=render

P. Kharaziha, « Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I-II clinical trial, Eur. J

, Gastroenterol. Hepatol, vol.21, issue.10, pp.1199-1205, 2009.

D. García-olmo, M. García-arranz, D. Herreros, I. Pascual, C. Peiro et al.,

. Rodríguez-montes, « A Phase I Clinical Trial of the Treatment of Crohn's Fistula by Adipose Mesenchymal Stem Cell Transplantation: », Dis. Colon Rectum, vol.48, issue.7, pp.1416-1423, 2005.

M. Duijvestein, « Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study, Gut, vol.59, pp.1662-1669, 2010.

M. Christopeit, M. Schendel, J. Föll, L. P. Müller, G. Keysser et al., « Marked improvement of severe progressive systemic sclerosis after transplantation of mesenchymal stem cells from an allogeneic haploidentical-related donor mediated by ligation of CD137L, Leukemia, vol.22, issue.5, pp.1062-1064, 2008.

S. Guiducci, « Autologous Mesenchymal Stem Cells Foster Revascularization of

, Ischemic Limbs in Systemic Sclerosis: A Case Report, vol.153, p.650, 2010.

J. Xu, « Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjogren syndrome, vol.120, pp.3142-3151, 2012.

E. Zappia, « Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy, Blood, vol.106, issue.5, pp.1755-1761, 2005.

Y. Nemoto, « Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4 memory T cells, Gut, vol.62, issue.8, pp.1142-1152, 2013.

J. Dalal, K. Gandy, and J. Domen, « Role of mesenchymal stem cell therapy in Crohn's disease », Pediatr. Res, vol.71, issue.2, pp.445-451, 2012.

K. and L. Blanc, « Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells, The Lancet, vol.363, pp.1439-1441, 2004.

K. and L. Blanc, « Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study, The Lancet, vol.371, pp.1579-1586, 2008.

R. Yañez, M. L. Lamana, J. García-castro, I. Colmenero, M. Ramírez et al., « Adipose Tissue-Derived Mesenchymal Stem Cells Have In Vivo Immunosuppressive Properties Applicable for the Control of the Graft-Versus-Host Disease, Stem Cells, vol.24, issue.11, pp.2582-2591, 2006.

L. M. Ball, « Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease, Br. J. Haematol, vol.163, issue.4, pp.501-509, 2013.

W. N. Brennen, S. R. Denmeade, and J. T. Isaacs, « Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment, Endocr. Relat. Cancer, vol.20, issue.5, pp.269-290, 2013.

S. Yoo, « Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model, Exp. Mol. Med, vol.40, p.387, 2008.

F. Dong, J. Harvey, A. Finan, K. Weber, U. Agarwal et al., « Myocardial CXCR4 Expression Is Required for Mesenchymal Stem Cell Mediated Repair Following Acute Myocardial Infarction, Circulation, vol.126, issue.3, pp.314-324, 2012.

R. Manuguerra-gagné, « Transplantation of Mesenchymal Stem Cells Promotes Tissue Regeneration in a Glaucoma Model Through Laser-Induced Paracrine Factor Secretion and Progenitor Cell Recruitment, STEM CELLS, vol.31, issue.6, pp.1136-1148, 2013.

T. Kinnaird and . Marrow, Derived Stromal Cells Express Genes Encoding a Broad Spectrum of Arteriogenic Cytokines and Promote In Vitro and In Vivo Arteriogenesis Through Paracrine Mechanisms », Circ. Res, vol.94, issue.5, pp.678-685, 2004.

S. Hung, R. R. Pochampally, S. Chen, S. Hsu, and D. J. Prockop, « Angiogenic Effects of Human Multipotent Stromal Cell Conditioned Medium Activate the PI3K-Akt Pathway in Hypoxic Endothelial Cells to Inhibit Apoptosis, Increase Survival, and Stimulate Angiogenesis, STEM CELLS, vol.25, issue.9, pp.2363-2370, 2007.

Y. Wu, L. Chen, P. G. Scott, and E. E. Tredget, Mesenchymal Stem Cells Enhance Wound Healing Through Differentiation and Angiogenesis, vol.25, pp.2648-2659, 2007.

R. A. Boomsma and D. L. Geenen, Mesenchymal Stem Cells Secrete Multiple Cytokines That Promote Angiogenesis and Have Contrasting Effects on Chemotaxis and Apoptosis, vol.7, p.35685, 2012.

R. Estrada, N. Li, H. Sarojini, J. An, M. Lee et al., « Secretome from mesenchymal stem cells induces angiogenesis via Cyr61, J. Cell. Physiol, vol.219, issue.3, pp.563-571, 2009.

M. Takahashi, « Adipose tissue-derived stem cells inhibit neointimal formation in a paracrine fashion in rat femoral artery, Am. J. Physiol.-Heart Circ. Physiol, vol.298, issue.2, pp.415-423, 2010.

A. I. Caplan and D. Correa, The MSC: An Injury Drugstore, vol.9, pp.11-15, 2011.

A. Bura, « Phase I trial: the use of autologous cultured adipose-derived stroma/stem cells to treat patients with non-revascularizable critical limb ischemia, Cytotherapy, vol.16, issue.2, pp.245-257, 2014.

C. Mias, « Mesenchymal Stem Cells Promote Matrix Metalloproteinase Secretion by Cardiac Fibroblasts and Reduce Cardiac Ventricular Fibrosis After Myocardial Infarction, Stem Cells, vol.27, issue.11, pp.2734-2743, 2009.

C. Alfarano, « Intraparenchymal Injection of Bone Marrow Mesenchymal Stem Cells Reduces Kidney Fibrosis after Ischemia-Reperfusion in Cyclosporine

». Immunosuppressed-rats, Cell Transplant, vol.21, issue.9, 2009.

A. Uccelli, L. Moretta, and V. Pistoia, « Mesenchymal stem cells in health and disease, Nat. Rev. Immunol, vol.8, issue.9, pp.726-736, 2008.

D. Giunti, « Mesenchymal Stem Cells Shape Microglia Effector Functions Through the Release of CX3CL1, Stem cells, vol.30, issue.9, pp.2044-2053, 2012.

N. B. Isele, « Bone marrow stromal cells mediate protection through stimulation of PI3-K/Akt and MAPK signaling in neurons, Neurochem. Int, vol.50, issue.1, pp.243-250, 2007.

I. Rosová, M. Dao, B. Capoccia, D. Link, and J. A. Nolta, Hypoxic Preconditioning Results in Increased Motility and Improved Therapeutic Potential of Human Mesenchymal Stem Cells, vol.26, pp.2173-2182, 2008.

J. M. , Canals, « Brain-Derived Neurotrophic Factor Regulates the Onset and Severity of Motor Dysfunction Associated with Enkephalinergic Neuronal Degeneration in

. Huntington's-disease, J. Neurosci, vol.24, pp.7727-7739, 2004.

S. Stemberger, A. Jamnig, N. Stefanova, G. Lepperdinger, M. Reindl et al.,

. Wenning, Mesenchymal Stem Cells in a Transgenic Mouse Model of Multiple System Atrophy: Immunomodulation and Neuroprotection, vol.6, p.19808, 2011.

S. Mora-lee, « Therapeutic Effects of hMAPC and hMSC Transplantation after Stroke in Mice, PLoS ONE, vol.7, issue.8, p.43683, 2012.

H. «-rammal, Comparaison de la capacité de différenciation en cellules endothéliales, de deux types de cellules souches mésenchymateuses issues de la gelée de Wharton et de la moelle osseuse (Doctoral dissertation, 2014.

M. Allel and B. Ahmed, « «Structures et Propriétés des Biomatériaux», cours en ligne, Université d'Oran des Sciences et de la Technologie Mohamed Boudiaf USTO-MB, Faculté de Physique, 2014.

E. B. Hunziker, « Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects, Osteoarthritis Cartilage, vol.10, issue.6, pp.432-463, 2002.

D. Nesic, R. Whiteside, M. Brittberg, D. Wendt, I. Martin et al., « Cartilage tissue engineering for degenerative joint disease?, Adv. Drug Deliv. Rev, vol.58, issue.2, pp.300-322, 2006.

N. Henry, « Médecine régénératrice du disque intervertébral: De la physiopathologie à l'application clinique », médecine/sciences, vol.30, pp.1091-1100, 2014.

A. M. Lincoff, J. G. Furst, S. G. Ellis, R. J. Tuch, and E. J. Topol, « Sustained Local Delivery of Dexamethasone by a Novel Intravascular Eluting Stent to Prevent Restenosis in the Porcine Coronary Injury Model, J. Am. Coll. Cardiol, vol.29, issue.4, pp.808-816, 1997.

G. C. Reilly and A. J. Engler, « Intrinsic extracellular matrix properties regulate stem cell differentiation, J. Biomech, vol.43, issue.1, pp.55-62

J. Elisseeff, A. Ferran, S. Hwang, S. Varghese, and Z. Zhang, The Role of Biomaterials in Stem Cell Differentiation: Applications in the Musculoskeletal System, vol.15, pp.295-303, 2006.

Y. Feng, M. Borrelli, S. Reichl, S. Schrader, and G. Geerling, Review of Alternative Carrier Materials for Ocular Surface Reconstruction, vol.39, pp.541-552, 2014.

M. Tallawi, « Strategies for the chemical and biological functionalization of scaffolds for cardiac tissue engineering: a review », J. R. Soc. Interface, vol.12, p.20150254, 2015.

L. Krishna, « Nanostructured scaffold as a determinant of stem cell fate, Stem Cell Res. Ther, vol.7, issue.1, 2016.

P. Gunatillake, R. Mayadunne, and R. Adhikari, Recent developments in biodegradable synthetic polymers, vol.12, pp.301-347, 2006.

F. E. Laydi, Effet de la nature des biomatériaux sur la différenciation des cellules souches mésenchymateuses (Doctoral dissertation, 2013.

S. Even-ram, V. Artym, and K. M. Yamada, « Matrix Control of Stem Cell Fate », Cell, vol.126, issue.4, pp.645-647, 2006.

A. J. Engler, S. Sen, H. L. Sweeney, and D. E. Discher, « Matrix Elasticity Directs Stem Cell Lineage Specification », Cell, vol.126, issue.4, pp.677-689, 2006.

B. L. Beckstead, S. Pan, A. D. Bhrany, A. M. Bratt-leal, B. D. Ratner et al.,

«. Giachelli, Esophageal epithelial cell interaction with synthetic and natural scaffolds for tissue engineering, Biomaterials, vol.26, pp.6217-6228, 2005.

Y. Zhu and M. B. Chan-park, Sin Chian, « The growth improvement of porcine esophageal smooth muscle cells on collagen

». Membrane and J. , Biomed. Mater. Res. B Appl. Biomater, vol.75, issue.1, pp.193-199, 2005.

C. E. Schmidt and J. M. Baier, Acellular vascular tissues: natural biomaterials for tissue repair and tissue engineering, vol.21, pp.2215-2231, 2000.

S. Tottey, M. Corselli, E. M. Jeffries, R. Londono, B. Peault et al., Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the

, Regenerative Potential of Perivascular Stem Cells, Tissue Eng. Part A, vol.17, issue.2, pp.37-44, 2011.

M. Geiger, « Collagen sponges for bone regeneration with rhBMP-2 », Adv. Drug Deliv. Rev, vol.55, pp.1613-1629, 2003.

T. R. Kuklo, A. T. Groth, R. C. Anderson, H. M. Frisch, and R. B. Islinger, « Recombinant human bone morphogenetic protein-2 for grade III open segmental tibial fractures from combat injuries in Iraq, J. Bone Joint Surg. Br, vol.90, issue.8, pp.1068-1072, 2008.

F. , Fibroblast biology in three-dimensional collagen matrices, vol.13, pp.264-269, 2003.

A. Mizuno, « Severe Osteoporosis in Mice Lacking Osteoclastogenesis Inhibitory Factor/Osteoprotegerin, Biochem. Biophys. Res. Commun, vol.247, issue.3, pp.610-615, 1998.

A. De-mel, G. Jell, M. M. Stevens, and A. M. Seifalian, Biofunctionalization of Biomaterials for Accelerated in Situ Endothelialization: A Review, vol.9, pp.2969-2979, 2008.

M. S. Kim, « Adhesion Behavior of Human Bone Marrow Stromal Cells on

, Differentially Wettable Polymer Surfaces, vol.13, issue.8, pp.2095-2103, 2007.

G. Decher, J. D. Hong, and J. Schmitt, Buildup of ultrathin multilayer films by a selfassembly process: III. Consecutively alternating adsorption of anionic and cationic polyelectrolytes on charged surfaces, Thin Solid Films, pp.831-835, 1992.

G. Decher, Fuzzy Nanoassemblies: Toward Layered Polymeric Multicomposites, vol.277, pp.1232-1237, 1997.

Y. Lvov, G. Decher, H. Haas, H. Möhwald, and A. Kalachev, « X-ray analysis of ultrathin polymer films self-assembled onto substrates, Phys. B Condens. Matter, vol.198, pp.89-91, 1994.

C. Picart and . Polyelectrolyte, Multilayer Films: From Physico-Chemical Properties to the Control of Cellular Processes, Curr. Med. Chem, vol.15, issue.7, pp.685-697, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00292253

S. S. Shiratori and M. F. Rubner, « pH-Dependent Thickness Behavior of Sequentially Adsorbed Layers of Weak Polyelectrolytes, Macromolecules, vol.33, issue.11, pp.4213-4219, 2000.

J. , Schlenoff, « Charge Balance and Transport in Ion-Paired Polyelectrolyte

;. G. Multilayers, J. B. Decher, . Schlenoff, . Éd, and . Weinheim, Multilayer Thin Films, pp.281-320, 2012.

J. C. Love, L. A. Estroff, J. K. Kriebel, R. G. Nuzzo, and G. M. Whitesides, SelfAssembled Monolayers of Thiolates on Metals as a Form of Nanotechnology, vol.105, pp.1103-1170, 2005.

S. M. Barlow and R. , Complex organic molecules at metal surfaces: bonding, organisation and chirality, vol.50, pp.201-341, 2003.

J. A. Elemans, S. Lei, S. De, and . Feyter, Molecular and Supramolecular Networks on Surfaces: From Two-Dimensional Crystal Engineering to Reactivity, vol.48, pp.7298-7332, 2009.

A. Pallandre, K. Glinel, A. M. Jonas, and B. Nysten, Binary Nanopatterned Surfaces Prepared from Silane Monolayers, vol.4, pp.365-371, 2004.

F. Schreiber, Structure and growth of self-assembling monolayers, Prog. Surf. Sci, vol.65, pp.151-257, 2000.

A. Ulman, « Formation and Structure of Self-Assembled Monolayers », Chem. Rev, vol.96, issue.4, pp.1533-1554, 1996.

S. R. Wasserman, Y. T. Tao, and G. M. Whitesides, Structure and reactivity of alkylsiloxane monolayers formed by reaction of alkyltrichlorosilanes on silicon substrates, vol.5, pp.1074-1087, 1989.

K. A. Kilian and M. Mrksich, « Directing Stem Cell Fate by Controlling the Affinity and Density of Ligand-Receptor Interactions at the Biomaterials Interface », Angew. Chem. Int. Ed, vol.51, pp.4891-4895, 2012.

G. A. Hudalla and W. L. Murphy, « Chemically well-defined self-assembled monolayers for cell culture: toward mimicking the natural ECM, Soft Matter, vol.7, p.9561, 2011.

M. Yamato, C. Konno, M. Utsumi, A. Kikuchi, and T. Okano, « Thermally responsive polymer-grafted surfaces facilitate patterned cell seeding and co-culture, Biomaterials, vol.23, issue.2, pp.561-567, 2002.

N. Aggarwal, N. Altgärde, S. Svedhem, G. Michanetzis, Y. Missirlis et al., Tuning Cell Adhesion and Growth on Biomimetic Polyelectrolyte Multilayers by Variation of pH During Layer-by-Layer Assembly: Tuning Cell Adhesion and Growth on Biomimetic

?. Polyelectrolyte, Macromol. Biosci, vol.13, issue.10, pp.1327-1338, 2013.

S. R. Pattabhi, A. M. Lehaf, J. B. Schlenoff, and T. C. Keller, Human mesenchymal stem cell osteoblast differentiation, ECM deposition, and biomineralization on PAH/PAA polyelectrolyte multilayers: PAH/PAA POLYELECTROLYTE

J. Multilayers-», Biomed. Mater. Res. A, vol.103, issue.5, pp.1818-1827, 2015.

A. M. Lehaf, H. H. Hariri, J. B. Schlenoff, and . Homogeneity, Modulus, and Viscoelasticity of Polyelectrolyte Multilayers by Nanoindentation: Refining the Buildup Mechanism, vol.28, pp.6348-6355, 2012.

A. T. Nguyen, S. R. Sathe, and E. K. Yim, « From nano to micro: topographical scale and its impact on cell adhesion, morphology and contact guidance, J. Phys. Condens

. Matter, , vol.28, p.183001, 2016.

R. G. Flemming, C. J. Murphy, G. A. Abrams, S. L. Goodman, and P. F. Nealey, Effects of synthetic micro-and nano-structured surfaces on cell behavior, Biomaterials, vol.20, issue.6, pp.573-588, 1999.

D. M. Le, K. Kulangara, A. F. Adler, K. W. Leong, and V. S. Ashby, « Dynamic Topographical Control of Mesenchymal Stem Cells by Culture on Responsive Poly(?-caprolactone) Surfaces », Adv. Mater, vol.23, pp.3278-3283, 2011.

F. Jiang and J. A. Doudna, « CRISPR-Cas9 Structures and Mechanisms », Annu. Rev. Biophys, vol.46, issue.1, pp.505-529, 2017.

A. Urciuolo, « Collagen VI regulates satellite cell self-renewal and muscle regeneration, Nat. Commun, vol.4, 2013.

X. Guo, Z. Cai, and Y. Gui, « Progress in the research of germ cell from human embryonic stem cells, Sheng Li Ke Xue Jin Zhan, vol.37, issue.1, pp.17-21, 2006.

E. Hadjipanayi, V. Mudera, and R. A. Brown, « Guiding cell migration in 3D: A collagen matrix with graded directional stiffness, Cell Motil. Cytoskeleton, vol.66, issue.3, pp.121-128, 2009.

J. P. Winer, P. A. Janmey, M. E. Mccormick, and M. Funaki, « Bone Marrow-Derived Human Mesenchymal Stem Cells Become Quiescent on Soft Substrates but Remain Responsive to Chemical or Mechanical Stimuli, Tissue Eng. Part A, vol.15, issue.1, pp.147-154, 2009.

G. Halder, S. Dupont, and E. S. Piccolo, « Transduction of mechanical and cytoskeletal cues by YAP and TAZ, Nat. Rev. Mol. Cell Biol, vol.13, issue.9, pp.591-600, 2012.

M. Arnold, Activation of Integrin Function by Nanopatterned Adhesive Interfaces, vol.5, pp.383-388, 2004.

S. Gerecht, C. J. Bettinger, Z. Zhang, J. T. Borenstein, and G. Vunjak-novakovic,

«. Langer, The effect of actin disrupting agents on contact guidance of human embryonic stem cells, Biomaterials, vol.28, pp.4068-4077, 2007.

H. Lin and A. C. Spradling, « Fusome asymmetry and oocyte determination inDrosophila, Dev. Genet, vol.16, issue.1, pp.6-12, 1995.

O. F. Harandi and V. R. Ambros, « Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans, Proc. Natl. Acad. Sci, vol.112, pp.287-296, 2015.

M. J. Dalby, « The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder, Nat. Mater, vol.6, pp.997-1003, 2007.

H. J. Anderson, J. K. Sahoo, R. V. Ulijn, and M. J. Dalby, « Mesenchymal Stem Cell Fate: Applying Biomaterials for Control of Stem Cell Behavior », Front. Bioeng. Biotechnol, vol.4, 2016.

E. Engel, E. Martínez, C. A. Mills, M. Funes, J. A. Planell et al., « Mesenchymal stem cell differentiation on microstructured poly (methyl methacrylate) substrates », Ann. Anat. -Anat. Anz, vol.191, issue.1, pp.136-144, 2009.

D. Ingber, « Extracellular matrix and cell shape: Potential control points for inhibition of angiogenesis, J. Cell. Biochem, vol.47, issue.3, pp.236-241, 1991.

D. E. Ingber, The mechanochemical basis of cell and tissue regulation », Mech. Chem. Biosyst. MCB, vol.1, issue.1, pp.53-68, 2004.

T. Lecuit and P. Lenne, « Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis, Nat. Rev. Mol. Cell Biol, vol.8, issue.8, pp.633-644, 2007.

S. H. Mcbride and M. L. Tate, « Modulation of Stem Cell Shape and Fate A: The Role of Density and Seeding Protocol on Nucleus Shape and Gene Expression, Tissue Eng. Part A, vol.14, issue.9, pp.1561-1572, 2008.

H. A. Awad, M. Q. Wickham, H. A. Leddy, J. M. Gimble, and F. Guilak,

, Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds, Biomaterials, vol.25, pp.3211-3222, 2004.

J. B. Hernandez, Anisotropie magnétique induite par modulation de surface et étude de la propagation de parois de domaines dans des nanostructures magnétiques (Doctoral dissertation, 2008.

H. «-riahi, Propriétés du réseau kagomé artificiel: micromagnétisme, chiralités et cristaux de charges émergents (Doctoral dissertation, 2013.

S. Hsu, C. Chen, P. S. Lu, C. Lai, and C. Chen, Biotechnol. Bioeng, vol.92, issue.5, pp.579-588, 2005.

Z. A. Cheng, O. F. Zouani, K. Glinel, A. M. Jonas, and M. Durrieu, Bioactive Chemical Nanopatterns Impact Human Mesenchymal Stem Cell Fate, vol.13, pp.3923-3929, 2013.

D. Zhang and K. A. Kilian, « The effect of mesenchymal stem cell shape on the maintenance of multipotency, Biomaterials, vol.34, pp.3962-3969, 2013.

J. Lee, A. A. Abdeen, D. Zhang, and K. A. Kilian, « Directing stem cell fate on hydrogel substrates by controlling cell geometry, matrix mechanics and adhesion ligand composition, Biomaterials, vol.34, pp.8140-8148, 2013.

K. A. Kilian, B. Bugarija, B. T. Lahn, and M. Mrksich, « Geometric cues for directing the differentiation of mesenchymal stem cells, Proc. Natl. Acad. Sci, vol.107, pp.4872-4877, 2010.

R. Mcbeath, D. M. Pirone, C. M. Nelson, K. Bhadriraju, and C. S. Chen, « Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment, Dev. Cell, vol.6, issue.4, pp.483-495, 2004.

A. J. Engler, F. Rehfeldt, S. Sen, D. E. Discher, and M. Elasticity, Measurements by Atomic Force Microscopy and Its Influence on Cell Differentiation, vol.83, pp.521-545, 2007.

H. Shin, S. Jo, and A. G. Mikos, « Biomimetic materials for tissue engineering », Biomaterials, vol.24, pp.4353-4364, 2003.

J. D. Krutty, S. K. Schmitt, P. Gopalan, and W. L. Murphy, « Surface functionalization and dynamics of polymeric cell culture substrates, Curr. Opin. Biotechnol, vol.40, pp.164-169, 2016.

S. Dupont, Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction, Exp. Cell Res, vol.343, issue.1, pp.42-53, 2016.

G. Halder, S. Dupont, and E. S. Piccolo, « Transduction of mechanical and cytoskeletal cues by YAP and TAZ, Nat. Rev. Mol. Cell Biol, vol.13, issue.9, pp.591-600, 2012.

Y. Sun, C. S. Chen, and J. Fu, « Forcing Stem Cells to Behave: A Biophysical Perspective of the Cellular Microenvironment, Annu. Rev. Biophys, vol.41, issue.1, pp.519-542

T. D. Ross, « Integrins in mechanotransduction, Curr. Opin. Cell Biol, vol.25, issue.5, pp.613-618, 2013.

M. A. Schwartz and D. W. Desimone, « Cell adhesion receptors in mechanotransduction, Curr. Opin. Cell Biol, vol.20, issue.5, pp.551-556, 2008.

V. I. Chubinskiy-nadezhdin, Y. A. Negulyaev, and E. A. Morachevskaya, « Functional coupling of ion channels in cellular mechanotransduction, Biochem. Biophys. Res. Commun, vol.451, issue.3, pp.421-424, 2014.

C. Ciobanasu, B. Faivre, and C. Le-clainche, « Integrating actin dynamics, mechanotransduction and integrin activation: The multiple functions of actin binding proteins in focal adhesions, Eur. J. Cell Biol, vol.92, pp.339-348, 2013.

A. J. Steward, D. R. Wagner, and D. J. Kelly, « Exploring the roles of integrin binding and cytoskeletal reorganization during mesenchymal stem cell mechanotransduction in soft and stiff hydrogels subjected to dynamic compression, J. Mech. Behav. Biomed. Mater, vol.38, pp.174-182, 2014.

G. R. Fedorchak, A. Kaminski, and J. Lammerding, « Cellular mechanosensing: Getting to the nucleus of it all, Prog. Biophys. Mol. Biol, vol.115, issue.2-3, pp.76-92, 2014.

F. Chamaraux, O. Ali, S. Keller, F. Bruckert, and B. Fourcade, « Physical model for membrane protrusions during spreading, Phys. Biol, vol.5, issue.3, p.36009, 2008.

M. Socol, C. Lefrou, F. Bruckert, D. Delabouglise, and M. Weidenhaupt, « Synchronization of Dictyostelium discoideum adhesion and spreading using electrostatic forces, Bioelectrochemistry, vol.79, issue.2, pp.198-210, 2010.

G. Keller, « Embryonic stem cell differentiation: emergence of a new era in biology and medicine, Genes Dev, vol.19, issue.10, pp.1129-1155, 2005.

R. J. Petrie, A. D. Doyle, and K. M. Yamada, « Random versus directionally persistent cell migration, Nat. Rev. Mol. Cell Biol, vol.10, issue.8, pp.538-549, 2009.

P. R. Morrison, J. T. Edsall, and S. G. Miller, « Preparation and Properties of Serum and Plasma Proteins. XVIII. The Separation of Purified Fibrinogen from Fraction I of Human Plasma. », J. Am. Chem. Soc, vol.70, issue.9, pp.3103-3108, 1948.

R. O. Hynes and K. M. Yamada, « Fibronectins: multifunctional modular glycoproteins, J. Cell Biol, vol.95, issue.2, pp.369-377, 1982.

J. E. Schwarzbauer, « Identification of the fibronectin sequences required for assembly of a fibrillar matrix, J. Cell Biol, vol.113, issue.6, pp.1463-1473, 1991.

J. R. Potts and I. D. Campbell, Fibronectin structure and assembly, vol.6, pp.648-655, 1994.

G. Niu and X. Chen, « Why integrin as a primary target for imaging and therapy, Theranostics, vol.1, pp.30-47, 2011.

J. L. Sechler, « A novel fibronectin binding site required for fibronectin fibril growth during matrix assembly, J. Cell Biol, vol.154, issue.5, pp.1081-1088, 2001.

K. S. Midwood, Y. Mao, H. C. Hsia, L. V. Valenick, and J. E. Schwarzbauer, « Modulation of Cell-Fibronectin Matrix Interactions during Tissue Repair

, Dermatol. Symp. Proc, vol.11, issue.1, pp.73-78, 2006.

N. Yang, R. Mosher, S. Seo, D. Beebe, and E. A. Friedl, « Syndecan-1 in Breast Cancer Stroma Fibroblasts Regulates Extracellular Matrix Fiber Organization and Carcinoma Cell Motility », Am. J. Pathol, vol.178, issue.1, pp.325-335, 2011.

J. L. Sechler, S. A. Corbett, and J. E. Schwarzbauer, « Modulatory Roles for Integrin Activation and the Synergy Site of Fibronectin during Matrix Assembly, Mol. Biol. Cell, vol.8, pp.2563-2573, 1997.

C. M. Klass, J. R. Couchman, and A. Woods, « Control of extracellular matrix assembly by syndecan-2 proteoglycan, J. Cell Sci, vol.113, pp.493-506, 2000.

V. Kostourou and V. Papalazarou, Non-collagenous ECM proteins in blood vessel morphogenesis and cancer, vol.1840, pp.2403-2413, 2014.

M. R. Morgan, M. J. Humphries, M. D. Bass, and . Synergistic, Nat. Rev. Mol. Cell Biol, vol.8, pp.957-969, 2007.

S. S. Akimov and A. M. , Belkin, « Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGFbetadependent matrix deposition, J. Cell Sci, vol.114, pp.2989-3000, 2001.

P. Chatakun, « The effect of five proteins on stem cells used for osteoblast differentiation and proliferation: a current review of the literature, Cell. Mol. Life Sci, vol.71, issue.1, pp.113-142, 2014.

K. E. Kadler, A. Hill, and E. G. Canty-laird, Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators, vol.20, pp.495-501, 2008.

M. C. Porté-durrieu, « Development of RGD peptides grafted onto silica surfaces: XPS characterization and human endothelial cell interactions, J. Biomed. Mater. Res, vol.46, issue.3, pp.368-375, 1999.

J. A. Rowley and D. J. Mooney, « Alginate type and RGD density control myoblast phenotype, J. Biomed. Mater. Res, vol.60, issue.2, pp.217-223, 2002.

P. R. Patel, Synthesis and Cell Adhesive Properties of Linear and Cyclic RGD Functionalized Polynorbornene Thin Films, vol.13, pp.2546-2553

N. Huebsch, « Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate, Nat. Mater, vol.9, issue.6, pp.518-526, 2010.

C. Mas-moruno, F. Rechenmacher, and H. Kessler, « Cilengitide: the first antiangiogenic small molecule drug candidate design, synthesis and clinical evaluation, Anticancer Agents Med. Chem, vol.10, issue.10, pp.753-768, 2010.

P. W. Kämmerer, M. Heller, J. Brieger, M. O. Klein, B. Al-nawas et al., « Immobilisation of linear and cyclic RGD-peptides on titanium surfaces and their impact on endothelial cell adhesion and proliferation, Eur. Cell. Mater, vol.21, pp.364-372, 2011.

J. M. Schober, L. F. Lau, T. P. Ugarova, S. C. , and -. Lam, « Identification of a Novel Integrin ?M?2 Binding Site in CCN1 (CYR61), a Matricellular Protein Expressed in Healing Wounds and Atherosclerotic Lesions, J. Biol. Chem, vol.278, pp.25808-25815, 2003.

P. D. Ellis, J. C. Metcalfe, M. Hyvönen, and P. R. Kemp, Adhesion of Endothelial Cells to NOV Is Mediated by the Integrins ?v?3 and ?5?1, J. Vasc. Res, vol.40, issue.3, pp.234-243, 2003.

R. Gao and D. R. Brigstock, « Connective Tissue Growth Factor (CCN2) Induces Adhesion of Rat Activated Hepatic Stellate Cells by Binding of Its C-terminal Domain to Integrin ? v ? 3 and Heparan Sulfate Proteoglycan, J. Biol. Chem, vol.279, issue.10, pp.8848-8855, 2004.

P. Kanchanawong, « Nanoscale architecture of integrin-based cell adhesions, Nature, vol.468, issue.7323, pp.580-584, 2010.

B. Geiger, J. P. Spatz, and A. D. Bershadsky, « Environmental sensing through focal adhesions, Nat. Rev. Mol. Cell Biol, vol.10, issue.1, pp.21-33, 2009.

J. E. Frith, R. J. Mills, J. E. Hudson, and J. J. Cooper-white, Tailored IntegrinExtracellular Matrix Interactions to Direct Human Mesenchymal Stem Cell Differentiation, vol.21, pp.2442-2456, 2012.

A. S. Rowlands, P. A. George, and J. J. , Cooper-White, « Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation », Am. J. Physiol.-Cell Physiol, vol.295, issue.4, pp.1037-1044, 2008.

F. Guilak, D. M. Cohen, B. T. Estes, J. M. Gimble, W. Liedtke et al., « Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix, Cell Stem Cell, vol.5, issue.1, pp.17-26, 2009.

A. Higuchi, Q. Ling, Y. Chang, S. Hsu, and E. A. Umezawa, « Physical Cues of Biomaterials Guide Stem Cell Differentiation Fate, Chem. Rev, vol.113, issue.5, pp.3297-3328, 2013.

B. Trappmann, « Extracellular-matrix tethering regulates stem-cell fate, Nat. Mater, vol.11, issue.7, pp.642-649, 2012.

J. R. Klim, L. Li, P. J. Wrighton, M. S. Piekarczyk, and L. L. Kiessling, « A defined glycosaminoglycan-binding substratum for human pluripotent stem cells, Nat. Methods, vol.7, pp.989-994, 2010.

S. T. Cowan, Abbreviation of Bacterial Generic Names, vol.120, pp.1103-1104

L. A. King, « Foodborne transmission of sorbitol-fermenting Escherichia coli O157:[H7] via ground beef: an outbreak in northern France, Clin. Microbiol. Infect, vol.20, pp.1136-1144, 2011.

J. D. Schilling, M. A. Mulvey, C. D. Vincent, R. G. Lorenz, and S. J. Hultgren, « Bacterial Invasion Augments Epithelial Cytokine Responses to Escherichia coli Through a Lipopolysaccharide-Dependent Mechanism, J. Immunol, vol.166, issue.2, pp.1148-1155, 2001.

O. Tenaillon, D. Skurnik, B. Picard, and E. E. Denamur, The population genetics of commensal Escherichia coli, vol.8, pp.207-217, 2010.

K. Ejrnaes, « Bacterial characteristics of importance for recurrent urinary tract infections caused by Escherichia coli, Dan. Med. Bull, vol.58, 2011.

K. Ejrnaes, « Characteristics of Escherichia coli causing persistence or relapse of urinary tract infections: phylogenetic groups, virulence factors and biofilm formation, Virulence, vol.2, issue.6, pp.528-537, 2011.

J. Yang, R. Bos, G. F. Belder, J. Engel, and H. J. Busscher, « Deposition of Oral Bacteria and Polystyrene Particles to Quartz and Dental Enamel in a Parallel Plate and Stagnation Point Flow Chamber, J. Colloid Interface Sci, vol.220, issue.2, pp.410-418, 1999.

L. A. Pratt and R. Kolter, « Genetic analysis of Escherichia coli biofilm formation: roles of flagella, motility, chemotaxis and type I pili, Mol. Microbiol, vol.30, issue.2, pp.285-293, 1998.

C. Prigent-combaret, G. Prensier, T. T. Le-thi, O. Vidal, P. Lejeune et al., « Developmental pathway for biofilm formation in curli-producing Escherichia coli strains: role of flagella, curli and colanic acid, Environ. Microbiol, vol.2, issue.4, pp.450-464, 2000.

A. J. De-kerchove and M. Elimelech, « Bacterial swimming motility enhances cell deposition and surface coverage, Environ. Sci. Technol, vol.42, pp.4371-4377, 2008.

R. M. Harshey, Bacterial Motility on a Surface: Many Ways to a Common Goal, Annu. Rev. Microbiol, vol.57, issue.1, pp.249-273, 2003.

M. Veuillet, Contrôle des propriétés mécaniques par polymérisation plasma pour des surfaces innovantes antibactériennes (Doctoral dissertation, 2017.

T. Proft and E. N. Baker, « Pili in Gram-negative and Gram-positive bacteriastructure, assembly and their role in disease, Cell. Mol. Life Sci, vol.66, issue.4, pp.613-635, 2009.

G. Zhou, « Uroplakin Ia is the urothelial receptor for uropathogenic Escherichia coli: evidence from in vitro FimH binding, J. Cell Sci, vol.114, pp.4095-4103, 2001.

Y. D. Tremblay, S. Hathroubi, and M. Jacques, « Bacterial biofilms: their importance in animal health and public health », Can. J. Vet. Res. Rev. Can. Rech

. Veterinaire, , vol.78, pp.110-116, 2014.

G. Stevenson, K. Andrianopoulos, M. Hobbs, and P. R. Reeves, « Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid. », J. Bacteriol, vol.178, pp.4885-4893, 1996.

R. Daniels, J. Vanderleyden, and J. Michiels, « Quorum sensing and swarming migration in bacteria, FEMS Microbiol. Rev, vol.28, issue.3, pp.261-289, 2004.
DOI : 10.1016/j.femsre.2003.09.004

URL : https://academic.oup.com/femsre/article-pdf/28/3/261/18126416/28-3-261.pdf

A. Reisner, J. A. Haagensen, M. A. Schembri, E. L. Zechner, and E. S. Molin, « Development and maturation of Escherichia coli K-12 biofilms: IncF plasmid promoted E. coli biofilm maturation, Mol. Microbiol, vol.48, issue.4, pp.933-946, 2003.
DOI : 10.1046/j.1365-2958.2003.03490.x

URL : https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2958.2003.03490.x

V. J. Savage, I. Chopra, and A. J. O'neill, Staphylococcus aureus Biofilms Promote Horizontal Transfer of Antibiotic Resistance, vol.57, 1968.

H. Flemming and J. Wingender, The biofilm matrix, vol.8, pp.623-633, 2010.

K. Driffield, K. Miller, J. M. Bostock, A. J. O'neill, and E. I. Chopra, « Increased mutability of Pseudomonas aeruginosa in biofilms, J. Antimicrob. Chemother, vol.61, issue.5, pp.1053-1056, 2008.

M. R. Parsek and T. Tolker-nielsen, Pattern formation in Pseudomonas aeruginosa biofilms, vol.11, pp.560-566, 2008.

S. Wuertz, S. Okabe, and M. Hausner, Microbial communities and their interactions in biofilm systems: an overview, vol.49, pp.327-336, 2004.

L. Ploux, A. Ponche, K. Anselme, and . Bacteria, Material Interfaces: Role of the Material and Cell Wall Properties, J. Adhes. Sci. Technol, vol.24, pp.2165-2201

N. Cottenye, K. Anselme, and L. Ploux, Vebert-Nardin, « Vesicular Structures SelfAssembled from Oligonucleotide-Polymer Hybrids: Mechanical Prevention of Bacterial Colonization Upon their Surface Tethering Through Hybridization, Adv. Funct. Mater, vol.22, issue.23, pp.4891-4898

N. «-cottenye, Antimicrobial surfaces based on self-assembled nanoreactors: from block copolymer synthesis to bacterial adhesion studies (Doctoral dissertation, 2010.

C. Guégan, « Alteration of bacterial adhesion induced by the substrate stiffness, Colloids Surf. B Biointerfaces, vol.114, pp.193-200, 2014.

K. W. Kolewe, S. R. Peyton, and J. D. Schiffman, Fewer Bacteria Adhere to Softer Hydrogels, vol.7, pp.19562-19569, 2015.
DOI : 10.1021/acsami.5b04269

URL : http://europepmc.org/articles/pmc4631609?pdf=render

Y. Wang, Interactions of Staphylococcus aureus with ultrasoft hydrogel biomaterials, vol.95, pp.74-85, 2016.

N. Saha, C. Monge, V. Dulong, C. Picart, and K. Glinel, Influence of Polyelectrolyte Film Stiffness on Bacterial Growth, vol.14, pp.520-528, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01067528

J. Tsibouklis, « Preventing bacterial adhesion onto surfaces: the low-surfaceenergy approach, Biomaterials, vol.20, issue.13, pp.1229-1235, 1999.

G. Speranza, « Role of chemical interactions in bacterial adhesion to polymer surfaces, Biomaterials, vol.25, issue.11, pp.2029-2037, 2004.

A. Terada, A. Yuasa, S. Tsuneda, A. Hirata, A. Katakai et al., « Elucidation of dominant effect on initial bacterial adhesion onto polymer surfaces prepared by radiationinduced graft polymerization, Colloids Surf. B Biointerfaces, vol.43, issue.2, pp.99-107, 2005.

B. Gottenbos, D. W. Grijpma, H. C. Van-der-mei, J. Feijen, and H. J. Busscher, « Antimicrobial effects of positively charged surfaces on adhering Gram-positive and Gramnegative bacteria, J. Antimicrob. Chemother, vol.48, issue.1, pp.7-13, 2001.

O. Rzhepishevska, S. Hakobyan, R. Ruhal, J. Gautrot, D. Barbero et al., « The surface charge of anti-bacterial coatings alters motility and biofilm architecture, Biomater. Sci, vol.1, issue.6, p.589, 2013.

J. F. Jones, J. D. Feick, D. Imoudu, N. Chukwumah, M. Vigeant et al., « Oriented Adhesion of Escherichia coli to Polystyrene Particles, Appl. Environ. Microbiol, vol.69, issue.11, pp.6515-6519, 2003.
DOI : 10.1128/aem.69.11.6515-6519.2003

URL : https://aem.asm.org/content/69/11/6515.full.pdf

Y. H. An and R. J. Friedman, « Concise review of mechanisms of bacterial adhesion to biomaterial surfaces, J. Biomed. Mater. Res, vol.43, issue.3, pp.338-348, 1998.

L. Ploux, S. Beckendorff, M. Nardin, and E. S. Neunlist, « Quantitative and morphological analysis of biofilm formation on self-assembled monolayers, Colloids Surf. B Biointerfaces, vol.57, issue.2, pp.174-181, 2007.

N. P. Boks, H. J. Kaper, W. Norde, H. C. Van-der-mei, and H. , Busscher, « Mobile and immobile adhesion of staphylococcal strains to hydrophilic and hydrophobic surfaces, J. Colloid Interface Sci, vol.331, issue.1, pp.60-64, 2009.

S. H. Flint, J. D. Brooks, and P. J. Bremer, « Properties of the stainless steel substrate, influencing the adhesion of thermo-resistant streptococci, J. Food Eng, vol.43, issue.4, pp.235-242, 2000.

L. Ploux, K. Anselme, A. Dirani, A. Ponche, O. Soppera et al., « Opposite Responses of Cells and Bacteria to Micro/Nanopatterned Surfaces Prepared by Pulsed Plasma Polymerization and UV-Irradiation, Langmuir, vol.25, issue.14, pp.8161-8169, 2009.

L. R. Hilbert, D. Bagge-ravn, J. Kold, and L. Gram, « Influence of surface roughness of stainless steel on microbial adhesion and corrosion resistance, Int. Biodeterior. Biodegrad, vol.52, issue.3, pp.175-185, 2003.

E. Medilanski, K. Kaufmann, L. Y. Wick, O. Wanner, and H. Harms, Influence of the Surface Topography of Stainless Steel on Bacterial Adhesion, vol.18, pp.193-203, 2002.

T. R. Scheuerman, A. K. Camper, and M. A. Hamilton, « Effects of Substratum Topography on Bacterial Adhesion, J. Colloid Interface Sci, vol.208, issue.1, pp.23-33, 1998.

C. Díaz, P. L. Schilardi, R. C. Salvarezza, and M. Fernández-lorenzo-de-mele, Nano/Microscale Order Affects the Early Stages of Biofilm Formation on Metal Surfaces, vol.23, pp.11206-11210, 2007.

K. Anselme, P. Davidson, A. M. Popa, M. Giazzon, M. Liley et al., « Response to comment on -The interaction of cells and bacteria with surfaces structures at the nanoscale? », Acta Biomater, vol.7, issue.4, pp.1936-1937, 2011.

D. Siegismund, A. Undisz, S. Germerodt, S. Schuster, and M. Rettenmayr, « Quantification of the interaction between biomaterial surfaces and bacteria by 3-D modeling, Acta Biomater, vol.10, issue.1, pp.267-275, 2014.

D. Zhang and K. A. Kilian, « Peptide microarrays for the discovery of bioactive surfaces that guide cellular processes: a single step azide-alkyne -click? chemistry approach, J Mater Chem B, vol.2, pp.4280-4288, 2014.

A. «-pallandre, Macromolecular Assemblies onto Chemically Nanopatterned Surfaces (Doctoral dissertation, 2004.

C. N. Hughes-chinkhota, « Oligonucleotide immobilization using 10-(carbomethoxy)decyl-dimethylchlorosilane for mRNA isolation and cDNA synthesis on a microfluidic chip, Sens. Actuators B Chem, vol.155, issue.2, pp.437-445, 2011.

S. Fiorilli, « Vapor-phase self-assembled monolayers of aminosilane on plasmaactivated silicon substrates, J. Colloid Interface Sci, vol.321, issue.1, pp.235-241, 2008.

M. Lösche, J. Schmitt, G. Decher, W. G. Bouwman, and K. Kjaer, « Detailed Structure of Molecularly Thin Polyelectrolyte Multilayer Films on Solid Substrates as Revealed by Neutron Reflectometry », Macromolecules, vol.31, pp.8893-8906, 1998.

R. Chen, J. A. Hunt, S. Fawcett, R. , R. Akhtar et al., « The optimization and production of stable homogeneous amine enriched surfaces with characterized nanotopographical properties for enhanced osteoinduction of mesenchymal stem cells: Opimization and Production of Stable Homogeneous Amine Enriched Surfaces, J. Biomed. Mater. Res. A, vol.106, issue.7, pp.1862-1877, 2018.

K. A. Whitehead, J. Colligon, and J. Verran, « Retention of microbial cells in substratum surface features of micrometer and sub-micrometer dimensions

B. Biointerfaces, , vol.41, pp.129-138, 2005.

D. Campoccia, Study of Staphylococcus Aureus Adhesion on a Novel Nanostructured Surface by Chemiluminometry, vol.29, pp.622-630, 2006.

V. A. Tegoulia and S. L. Cooper, « Staphylococcus aureus adhesion to self-assembled monolayers: effect of surface chemistry and fibrinogen presence, Colloids Surf. B Biointerfaces, vol.24, pp.217-228, 2002.

B. Li and B. E. Logan, « Bacterial adhesion to glass and metal-oxide surfaces, Colloids Surf. B Biointerfaces, vol.36, issue.2, pp.81-90, 2004.

P. Krsko, J. B. Kaplan, and M. Libera, « Spatially controlled bacterial adhesion using surface-patterned poly(ethylene glycol) hydrogels », Acta Biomater, vol.5, issue.2, pp.589-596, 2009.

G. Patras, M. Katsikogianni, and Y. Missirlis, « Concise review of mechanisms of bacterial adhesion to biomaterials and of techniques used in estimating bacteria-material interactions, Eur. Cell. Mater, vol.8, pp.37-57, 2004.

L. G. Harris, S. Tosatti, M. Wieland, M. Textor, and R. G. Richards, « Staphylococcus aureus adhesion to titanium oxide surfaces coated with non-functionalized and peptidefunctionalized poly(l-lysine)-grafted-poly(ethylene glycol) copolymers, Biomaterials, vol.25, pp.4135-4148, 2004.

L. F. Thompson, C. G. Willson, M. J. Bowden, and É. , Introduction to microlithography, 1994.

S. A. Campbell, The science and engineering of microelectronic fabrication, 2001.

E. A. Dobisz, S. L. Brandow, R. Bass, and J. Mitterender, « Effects of molecular properties on nanolithography in polymethyl methacrylate, J. Vac. Sci. Technol. B Microelectron. Nanometer Struct, vol.18, issue.1, p.107, 2000.

M. A. Auty, Situ Viability Assessment of Bacteria in Probiotic Dairy Products Using Viability Staining in Conjunction with Confocal Scanning Laser Microscopy, janv. 2001. ou traitées de façon homogène ou patternée avec des molécules naturelles (la FN et le peptide RGD cyclique). Ensuite, nous avons étudié le taux de recouvrement et la taille des bactéries, vol.67, pp.420-425

, Leur taux de recouvrement varie significativement pour une surface donnée. En effet, le taux de recouvrement et la taille maximaux sont observés sur des surfaces patternées greffées avec la FN, ce qui prouve leur efficacité et l'impact qu'elles ont sur le comportement de E.coli, Nous avons donc démontré dans ce travail de thèse l'influence des propriétés de surfaces sur la croissance de cellules vivantes telles que les cellules souches ou les bactéries

. Mots-clés, Cellules souches Mésenchymateuses -Mécanotransduction -Différenciation -Chimie contrôlée -Géométrie contrôlée -souche E.coli -Adhésion