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H. Hv and C. .. , Comparaisons des groupes, p.215

C. .. Panss-et, Comparaisons des groupes PANSS+

, Nombre de FA, indice d' et indice log? selon l'amorçage émotionnel 218

, Nombre de FA, indice d' et indice log? sur l'ensemble de la tâche, p.223

, Discussion générale et limites des études Propension et Hallucination

. .. , Discussion générale et perspectives futures

.. .. Le-plan-recherche,

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, Electronic address: florent.bernardin@cpn-laxou.com 3-Université de Lorraine, Vandoeuvre-lés, 5-Maison des Addictions

, Journal: Schizophrenia Research Article type: full-length paper Running title: Retinal ganglion cells dysfunctions in schizophrenia patients with or without

, Retinal Ganglion Cells, Retina, flash Electroretinogram, Pattern Electroretinogram, Visual Hallucinations

A. Mann-whitney, There was no significant difference between the controls (median=24.0 [IC 95%, 23:27]) and the schizophrenia patients (24.0 [25:31]) (U=384.5, p=n.s) for age. Differences were noted between the groups in terms of years of education

, PERG parameters (P50 and N95 amplitudes and implicit times

, We found an increase in the mean P50 implicit time in the schizophrenia patients compared with the controls (t(55)=2.1, p<.05, d = 0.55)

, No significant differences between groups were found for the mean P50 (t(55)=0.6), p=n.s) and the mean N95 amplitudes (t(55)=0.4, p=n.s) between groups

, Spearman rank-order correlations performed in the schizophrenia patients group for b-wave amplitudes showed a significant correlation with the PANSS general score

, The a-wave amplitude was significantly decreased in the schizophrenia patients compared to the controls (t(48)=4.7, p<.001, d =1.33). The b-wave amplitude was also significantly decreased in the schizophrenia

, No significant differences between groups were found for a-wave implicit time (t(48)=-1.8, p=n.s) and b-wave implicit time (t(48between PANSS negative score and a-wave implicit time

, The a-wave implicit time was significantly decreased in the schizophrenia patients compared to the controls (t(52)=-2.5, p<.05, d =1.19). The a-wave amplitude was significantly decreased in the schizophrenia

, A post-hoc Tukey test revealed a tendency for increased P50 implicit time in the VH group compared to controls (p=.08), a tendency for increased N95 implicit time in the VH group compared to the controls (p=.06) and a significant increase of the N95 implicit time in the AHNH group compared to the controls (p<.001) (fig. 2), An ANOVA was conducted on the P50 and N95 amplitudes and implicit times and revealed a significant effect of group

, A post-hoc Tukey test showed a significant reduced a-wave amplitude in the VH group compared to the controls (p<.05) and in the AHNH group compared to the controls (p<.005). Kruskal-Wallis ANOVAs conducted for a-and b-wave implicit time did not reveal any significant differences, Spearman rank-order correlations performed in the VH group showed a significant correlation between lifetime VH repercussion score and b-wave implicit time (r=0.70, p<.05) indicating of group

, An ANOVA was conducted between the 3 groups on a-wave amplitude, a-wave implicit time and b-wave amplitude and revealed no significant effect. Kruskal-Wallis ANOVAs conducted for a-wave implicit time and b-wave implicit time revealed a tendency for a-wave implicit time

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