L. L. Hench, R. J. Splinter, W. C. Allen, and T. K. Greenlee, « Bonding mechanisms at the interface of ceramic prosthetic materials, Journal of Biomedical Materials Research, vol.5, issue.6, pp.117-141, 1971.

Y. Ebisawa, T. Kokubo, K. Ohura, T. Yamamuro, . Bioactivity et al., SiO2-based glasses:in vitro evaluation, Journal of Materials Science: Materials in Medicine, vol.1, pp.239-244, 1990.

S. Fujibayashi, A comparative study between in vivo bone ingrowth and in vitro apatite formation on Na2O-CaO-SiO2 glasses, vol.24, pp.1349-1356, 2003.

L. L. Hench and . Bioceramics, From Concept to Clinic », Journal of the American Ceramic Society, vol.74, issue.7, pp.1487-1510

A. Tilocca, « Structural models of bioactive glasses from molecular dynamics simulations, Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol.465, pp.1003-1027, 2009.

A. J. Salinas, A. I. Martin, and M. Vallet-regí, Bioactivity of three CaO-P 2 O 5 -SiO 2 sol-gel glasses: CaO-P 2 O 5 -SiO 2 Sol-Gel Glasses, Journal of Biomedical Materials Research, vol.61, issue.4, pp.524-532, 2002.

A. Tilocca, A. N. Cormack, and N. H. De-leeuw, The Structure of Bioactive Silicate Glasses: New Insight from Molecular Dynamics Simulations, vol.19, pp.95-103, 2007.

G. Lusvardi, Elucidation of the Structural Role of Fluorine in Potentially Bioactive Glasses by Experimental and Computational Investigation, vol.112, pp.12730-12739, 2008.

K. Ohura, « Bone-bonding ability of P 2 O 5 -Free CaO · SiO 2 glasses: BONE-BONDING OF P 2 O 5 -Free CaO, Journal of Biomedical Materials Research, vol.25, issue.3, pp.357-365, 1991.

T. Kokubo, H. Kim, and M. Kawashita, « Novel bioactive materials with different mechanical properties, Biomaterials, vol.24, issue.13, pp.2161-2175, 2003.

A. K. Soper, « Radical re-appraisal of water structure in hydrophilic confinement, Chemical Physics Letters, vol.590, pp.1-15

A. K. Soper, « Density profile of water confined in cylindrical pores in MCM-41 silica », Journal of Physics: Condensed Matter, vol.24, issue.6, p.64107

A. Schreiber, I. Ketelsen, and G. H. Findenegg, « Melting and freezing of water in ordered mesoporous silica materials, Physical Chemistry Chemical Physics, vol.3, issue.7, pp.1185-1195, 2001.

J. Walia, « Temperature and hydration dependence of proton MAS NMR spectra in MCM-41: Model based on motion induced chemical shift averaging, Solid State Nuclear Magnetic Resonance, pp.26-32, 2013.

S. Kittaka, S. Takahara, H. Matsumoto, Y. Wada, T. J. Satoh et al., Low temperature phase properties of water confined in mesoporous silica MCM-41: Thermodynamic and neutron scattering study, vol.138, p.204714, 2013.

S. Jähnert, F. Vaca-chávez, G. E. Schaumann, A. Schreiber, M. Schönhoff et al., Melting and freezing of water in cylindrical silica nanopores, Physical Chemistry Chemical Physics, vol.10, p.6039, 2008.

N. Bchellaoui, Z. Hayat, M. Mami, R. Dorbez-sridi, and E. A. , El Abed, « Microfluidicassisted Formation of Highly Monodisperse and Mesoporous Silica Soft Microcapsules, Scientific Reports, vol.7, issue.1, 2017.

A. K. Soper, « Empirical potential Monte Carlo simulation of fluid structure, Chemical Physics, vol.202, issue.2-3, pp.357-363, 1996.

F. G. Barker, Repairing Holes in the Head: A History of Cranioplasty, vol.41, pp.999-999, 1997.

W. S. Pietrzak, « Musculoskeletal and Wound Treatment Through the Ages: A Brief Historical Tour, pp.3-17, 2008.

A. Bobbio, « The first endosseous alloplastic implant in the history of man, Bull Hist Dent, vol.20, issue.1, pp.1-6

E. Crubzy, P. Murail, L. Girard, and J. Bernadou, « False teeth of the Roman world, Nature, vol.391, pp.29-29, 1998.

«. Biomaterials, Biomaterials Science, pp.p. xli-liii, 2013.

L. L. Hench, « (ii) The challenge of orthopaedic materials, Current Orthopaedics, vol.14, issue.1, pp.7-15, 2000.

R. Schmidt, L. Künzi, and R. Schmidt, Comportement des matériaux dans les milieux biologiques: applications en médecine et biotechnologie, 1. éd. Lausanne: Presses Polytechniques et Universitaires Romandes, 1999.

W. Cao and L. L. Hench, Ceramics International, vol.22, issue.6, pp.493-507, 1996.

M. Arioua, «. De, and . Bioactif, , p.115

J. R. Jones and L. L. Hench, Biomedical materials for new millennium: perspective on the future, vol.17, pp.891-900, 2001.

F. Gaudière, « Développement de revêtements bioactifs pour les biomatériaux : Modulation des comportements cellulaires en fonction du microenvironnement physico-chimique et mécanique, 2013.

S. Beauvais, « Etude de l'influence de la porosité sur les propriétés électriques de dépôts réalisés par projection plasma, p.240

T. Albrektsson, C. Johansson, and . Osteoinduction, , p.6

L. G. Donaruma, D. F. Definitions-in-biomaterials, and . Williams, Journal of Polymer Science: Polymer Letters Edition, vol.72, issue.9, pp.414-414, 1987.

N. and L. Ounalli, « Investigation après immersion dans un liquide physiologique synthétique, de l'interface de verres bioactifs à porosité contrôlée : influence des paramètres de synthèse sur les propriétés physico-chimiques et biologiques, 2014.

M. Becke-goehring and ;. J. Van-wazer, Bd. 1: Chemistry, von, Phosphorus and its Compounds, vol.50, pp.552-552, 1958.

J. A. Antonio, W. N. Capello, and W. L. Jaffe, Multicenter three-year clinical and roentgenographic results, Hydroxylapatite-coated hip implants, pp.102-115

M. Jarcho, Biomaterial aspects of calcium phosphates. Properties and applications, vol.30, pp.25-47, 1986.

C. Rey, C. Combes, C. Drouet, H. Sfihi, and A. Barroug, « Physico-chemical properties of nanocrystalline apatites: Implications for biominerals and biomaterials, Materials Science and Engineering: C, vol.27, issue.2, pp.198-205, 2007.

H. M. Da-silva, « Surface transformation of silicon-doped hydroxyapatite immersed in culture medium under dynamic and static conditions, Colloids and Surfaces B: Biointerfaces, vol.75, issue.1, pp.349-355

E. M. Carlisle and . Silicon, A Possible Factor in Bone Calcification, Science, vol.167, pp.279-280

M. Germaini, « Elaboration de céramiques phosphocalciques pour l'ingénierie tissulaire osseuse: étude de l'influence des propriétés physico-chimiques des matériaux sur le comportement biologique in vitro, p.284

L. L. Hench and . Bioceramics, From Concept to Clinic », Journal of the American Ceramic Society, vol.74, issue.7, pp.1487-1510

L. L. Hench, R. J. Splinter, W. C. Allen, and T. K. Greenlee, « Bonding mechanisms at the interface of ceramic prosthetic materials, Journal of Biomedical Materials Research, vol.5, issue.6, pp.117-141, 1971.

L. L. Hench, Chronology of Bioactive Glass Development and Clinical Applications », NJGC, vol.03, pp.67-73, 2013.

G. N. Greaves and «. Exafs, Journal of Non-Crystalline Solids, vol.71, pp.90289-90292, 1985.

G. N. Greaves and S. Sen, « Inorganic glasses, glass-forming liquids and amorphizing solids, Advances in Physics, vol.56, issue.1, pp.1-166, 2007.

R. Li, A. E. Clark, and L. L. Hench, « An investigation of bioactive glass powders by sol-gel processing, Journal of Applied Biomaterials, vol.2, issue.4, pp.231-239, 1991.

M. M. Pereira, A. E. Clark, and L. L. Hench, « Calcium phosphate formation on solgel-derived bioactive glassesin vitro, Journal of Biomedical Materials Research, vol.28, issue.6, pp.693-698, 1994.

A. Martínez, I. Izquierdo-barba, and M. Vallet-regí, Bioactivity of a CaO?SiO 2 Binary Glasses System, vol.12, pp.3080-3088, 2000.

F. Balas, D. Arcos, J. Pérez-pariente, and M. Vallet-regí, « Textural properties of SiO 2 · CaO · P 2 O 5 glasses prepared by the sol-gel method », Journal of Materials Research, vol.16, issue.5, pp.1345-1348, 2001.

M. Ogino, F. Ohuchi, and L. L. Hench, « Compositional dependence of the formation of calcium phosphate films on bioglass, Journal of Biomedical Materials Research, vol.14, issue.1, pp.55-64

A. E. Clark, C. G. Pantano, and L. L. Hench, « Auger Spectroscopic Analysis of Bioglass Corrosion Films, Journal of the American Ceramic Society, vol.59, issue.2, pp.37-39

O. Peitl, E. D. Zanotto, and L. L. Hench, « Highly bioactive P2O5-Na2O-CaO-SiO2 glass-ceramics », Journal of Non-Crystalline Solids, vol.292, issue.1-3, pp.115-126, 2001.

M. Cerruti, D. Greenspan, and K. Powers, Effect of pH and ionic strength on the reactivity of Bioglass® 45S5, vol.26, pp.1665-1674, 2005.

P. Sepulveda, J. R. Jones, and L. L. Hench, « In vitro dissolution of melt-derived 45S5 and sol-gel derived 58S bioactive glasses, Journal of Biomedical Materials Research, vol.61, issue.2, pp.301-311, 2002.

D. Arcos, D. C. Greenspan, and M. Vallet-regí, « A new quantitative method to evaluate the in vitro bioactivity of melt and sol-gel-derived silicate glasses: Bioactivity of Silicate Glasses », Journal of Biomedical Materials Research Part A, vol.65, issue.3, pp.344-351, 2003.

T. Kokubo, Surface chemistry of bioactive glass-ceramics », vol.120, p.90199

S. Padilla, J. Román, A. Carenas, and M. Vallet-reg?, The influence of the phosphorus content on the bioactivity of sol-gel glass ceramics, vol.26, pp.475-483, 2005.

A. Tilocca, « Structural models of bioactive glasses from molecular dynamics simulations, Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol.465, pp.1003-1027, 2009.

K. Ohura, « Bone-bonding ability of P 2 O 5 -Free CaO · SiO 2 glasses: BONE-BONDING OF P 2 O 5 -Free CaO SiO 2 GLASSES », Journal of Biomedical Materials Research, vol.25, issue.3, pp.357-365, 1991.

T. Kokubo, H. Kim, and M. Kawashita, « Novel bioactive materials with different mechanical properties, Biomaterials, vol.24, issue.13, pp.2161-2175, 2003.

H. Ltd, Tissue-biomaterial interactions, p.25

P. Exbrayat, La biocompatibilité des matériaux dentaires, pp.177-202, 1998.

Y. Ebisawa and T. Kokubo, Bioactivity of CaO ? Si02-based glasses: in vitro evaluation, p.6

S. Fujibayashi, A comparative study between in vivo bone ingrowth and in vitro apatite formation on Na2O-CaO-SiO2 glasses, vol.24, pp.1349-1356, 2003.

E. Leonova, « Multinuclear Solid-State NMR Studies of Ordered Mesoporous Bioactive Glasses, The Journal of Physical Chemistry C, vol.112, issue.14, pp.5552-5562, 2008.

G. Malavasi, L. Menabue, M. C. Menziani, A. Pedone, and A. J. Salinas, Vallet-Regí, « New insights into the bioactivity of SiO2-CaO and SiO2-CaO-P2O5 sol-gel glasses by molecular dynamics simulations », Journal of Sol-Gel Science and Technology, vol.67, issue.1, pp.208-219

D. Arcos and M. Vallet-regí, « Sol-gel silica-based biomaterials and bone tissue regeneration, Acta Biomaterialia, vol.6, issue.8, pp.2874-2888, 2010.

T. Peltola, « Calcium phosphate formation on porous sol-gel-derived SiO2 and CaO-P2O5-SiO2 substratesin vitro, Journal of Biomedical Materials Research, vol.44, issue.1, pp.12-21

J. P. Nayak and J. Bera, Effect of sintering temperature on mechanical behaviour and bioactivity of sol-gel synthesized bioglass-ceramics using rice husk ash as a silica source, Applied Surface Science, vol.257, issue.2, pp.458-462, 2010.

J. E. Lemons-;-t.-yamamuro, L. Hench, and J. , bioactive glasses and glassceramics and, vol.1, pp.903-904, 1990.

L. L. Hench, Life and death: the ultimate phase transformation, Thermochimica Acta, pp.1-13, 1996.

P. Sepulveda, J. R. Jones, and L. L. Hench, « Bioactive sol-gel foams for tissue repair, Journal of Biomedical Materials Research, vol.59, issue.2, pp.340-348, 2002.

F. Mezahi, A. L. Girot, H. Oudadesse, and A. Harabi, Reactivity kinetics of 52S4 glass in the quaternary system SiO2-CaO-Na2O-P2O5: Influence of the synthesis process: Melting versus sol-gel », vol.361, pp.111-118
URL : https://hal.archives-ouvertes.fr/hal-00813677

J. Ma, C. Z. Chen, D. G. Wang, and J. Z. Shi, « Textural and structural studies of solgel derived SiO2-CaO-P2O5-MgO glasses by substitution of MgO for CaO, Materials Science and Engineering: C, vol.30, issue.6, pp.886-890

J. Trébosc, J. W. Wiench, S. Huh, V. S. Lin, and M. Pruski, Solid-State NMR Study of MCM-41-type Mesoporous Silica Nanoparticles », vol.127, pp.3057-3068, 2005.

J. Walia, « Temperature and hydration dependence of proton MAS NMR spectra in MCM-41: Model based on motion induced chemical shift averaging, Solid State Nuclear Magnetic Resonance, pp.26-32, 2013.

S. H. Lee and P. J. Rossky, « A comparison of the structure and dynamics of liquid water at hydrophobic and hydrophilic surfaces-a molecular dynamics simulation study, The Journal of Chemical Physics, vol.100, issue.4, pp.3334-3345, 1994.

M. Rovere, M. A. Ricci, D. Vellati, and F. Bruni, « A molecular dynamics simulation of water confined in a cylindrical SiO2 pore, The Journal of Chemical Physics, vol.108, issue.23, pp.9859-9867, 1998.

L. B. Mccusker, F. Liebau, and G. Engelhardt, Nomenclature of structural and compositional characteristics of ordered microporous and mesoporous materials with inorganic hosts(IUPAC Recommendations 2001), vol.73, pp.381-394, 2001.

J. Y. Ying, C. P. Mehnert, and M. S. Wong, Synthesis and Applications of Supramolecular-Templated Mesoporous Materials, vol.38, pp.56-77, 19990115.

C. J. Brinker, Porous inorganic materials, p.8

A. Sayari, « Catalysis by Crystalline Mesoporous Molecular Sieves, 1995.

H. Yang, A. Kuperman, N. Coombs, S. Mamiche-afara, and G. A. Ozin, « Synthesis of oriented films of mesoporous silica on mica, Nature, vol.379, pp.703-705, 1996.

M. E. Davis, « Ordered porous materials for emerging applications, Nature, vol.417, pp.813-821, 2002.

A. Stein, Advances in Microporous and Mesoporous Solids-Highlights of Recent Progress », vol.15, pp.763-775, 2003.

J. Salonen, « Mesoporous silicon microparticles for oral drug delivery: Loading and release of five model drugs, Journal of Controlled Release, vol.108, issue.2-3, pp.362-374, 2005.

I. Izquierdo-barba, Á. Martinez, A. L. Doadrio, J. Pérez-pariente, and M. Vallet-regí, « Release evaluation of drugs from ordered three-dimensional silica structures, European Journal of Pharmaceutical Sciences, vol.26, issue.5, pp.365-373, 2005.

Q. Yang, « pH-Responsive Carrier System Based on Carboxylic Acid Modified Mesoporous Silica and Polyelectrolyte for Drug Delivery, Chemistry of Materials, vol.17, pp.5999-6003, 2005.

M. Vallet-regí, I. Izquierdo-barba, A. Rámila, J. Pérez-pariente, F. Babonneau et al., González-Calbet, « Phosphorous-doped MCM-41 as bioactive material, Solid State Sciences, vol.7, issue.2, pp.233-237, 2005.

X. Yan, C. Yu, X. Zhou, J. Tang, and D. Zhao, Highly Ordered Mesoporous Bioactive Glasses with Superior In Vitro Bone-Forming Bioactivities, vol.43, pp.5980-5984, 2004.

X. X. Yan, « Mesoporous bioactive glasses. I. Synthesis and structural characterization », Journal of Non-Crystalline Solids, vol.351, pp.3209-3217, 2005.

J. Lu, « Mesoporous Silica Nanoparticles for Cancer Therapy: Energy-Dependent Cellular Uptake and Delivery of Paclitaxel to Cancer Cells, NanoBiotechnology, vol.3, issue.2, pp.89-95, 2007.

J. Lu, E. Choi, F. Tamanoi, J. I. Zink, and . Light, Activated Nanoimpeller-Controlled Drug Release in Cancer Cells, Small, vol.4, pp.421-426, 2008.

J. Lu, M. Liong, J. I. Zink, and F. Tamanoi, Mesoporous Silica Nanoparticles as a Delivery System for Hydrophobic Anticancer Drugs, vol.3, pp.1341-1346, 2007.

Q. He, « One-pot self-assembly of mesoporous silica nanoparticle-based pHresponsive anti-cancer nano drug delivery system, Journal of Materials Chemistry, vol.21, p.15190, 2011.

L. Pasqua, S. Cundari, C. Ceresa, and G. Cavaletti, Recent Development, Applications, and Perspectives of Mesoporous Silica Particles in Medicine and Biotechnology, vol.16, pp.3054-3063, 2009.

C. Tourné-péteilh, « Synthesis and characterisation of ibuprofen-anchored MCM-41 silica and silica gel », New J. Chem, vol.27, issue.10, pp.1415-1418, 2003.

Y. A. Shchipunov, Y. V. Burtseva, T. Yu, N. M. Karpenko, T. N. Shevchenko et al., « Highly efficient immobilization of endo-1,3-?-d-glucanases (laminarinases) from marine mollusks in novel hybrid polysaccharide-silica nanocomposites with regulated composition, Journal of Molecular Catalysis B: Enzymatic, vol.40, issue.2, pp.16-23, 2006.

H. Chen, Label-Free Luminescent Mesoporous Silica Nanoparticles for Imaging and Drug Delivery », Theranostics, vol.3, pp.650-657, 2013.

J. Xie, S. Lee, X. Chen, and . Nanoparticle, Advanced Drug Delivery Reviews, vol.62, issue.11, pp.1064-1079, 2010.

M. Vallet-regí, F. Balas, and D. Arcos, Mesoporous Materials for Drug Delivery, vol.46, pp.7548-7558, 2007.

Q. Gao, Y. Xu, D. Wu, Y. Sun, and X. Li, « pH-Responsive Drug Release from Polymer-Coated Mesoporous Silica Spheres, vol.113, pp.12753-12758, 2009.

Y. Gao, « Controlled Intracellular Release of Doxorubicin in Multidrug-Resistant Cancer Cells by Tuning the Shell-Pore Sizes of Mesoporous Silica Nanoparticles, ACS Nano, vol.5, pp.9788-9798

J. Andersson, J. Rosenholm, S. Areva, and M. Lindén, Influences of Material Characteristics on Ibuprofen Drug Loading and Release Profiles from Ordered Microand Mesoporous Silica Matrices, Chemistry of Materials, vol.16, pp.4160-4167, 2004.

B. G. Trewyn, I. I. Slowing, S. Giri, H. Chen, V. S. et al., Synthesis and Functionalization of a Mesoporous Silica Nanoparticle Based on the Sol-Gel Process and Applications in Controlled Release, Accounts of Chemical Research, vol.40, issue.9, pp.846-853

F. Qu, « Controlled release of Captopril by regulating the pore size and morphology of ordered mesoporous silica, Microporous and Mesoporous Materials, vol.92, issue.1-3, pp.1-9, 2006.

M. Manzano, M. Colilla, and M. Vallet-regí, Drug delivery from ordered mesoporous matrices, vol.6, pp.1383-1400

P. L. Abbaraju, « Floating tablets from mesoporous silica nanoparticles, J. Mater. Chem. B, vol.2, pp.8298-8302, 2014.

A. Popat, « Adsorption and release of biocides with mesoporous silica nanoparticles, Nanoscale, vol.4, pp.970-975, 2012.

I. Izquierdo-barba, Influence of mesoporous structure type on the controlled delivery of drugs: release of ibuprofen from MCM-48, SBA-15 and functionalized SBA-15 », vol.50, pp.421-429, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00411185

W. Zeng, X. Qian, Y. Zhang, J. Yin, and Z. Zhu, « Organic modified mesoporous MCM-41 through solvothermal process as drug delivery system, Materials Research Bulletin, vol.40, issue.5, pp.766-772, 2005.

T. P. Nguyen, J. Lee, W. G. Shim, and H. Moon, « Synthesis of functionalized SBA-15 with ordered large pore size and its adsorption properties of BSA, Microporous and Mesoporous Materials, vol.110, issue.2-3, pp.560-569, 2008.

A. Nieto, F. Balas, M. Colilla, and M. Manzano, Vallet-Regí, « Functionalization degree of SBA-15 as key factor to modulate sodium alendronate dosage, Microporous and Mesoporous Materials, vol.116, issue.1-3, pp.4-13, 2008.

Q. Tang, Y. Xu, D. Wu, and Y. Sun, « Hydrophobicity-controlled Drug Delivery System from Organic Modified Mesoporous Silica, Chemistry Letters, vol.35, issue.5, pp.474-475, 2006.

T. Xia, « Polyethyleneimine Coating Enhances the Cellular Uptake of Mesoporous Silica Nanoparticles and Allows Safe Delivery of siRNA and DNA Constructs, ACS Nano, vol.3, issue.10, pp.3273-3286, 2009.

H. Meng, « Engineered Design of Mesoporous Silica Nanoparticles to Deliver Doxorubicin and P-Glycoprotein siRNA to Overcome Drug Resistance in a Cancer Cell Line, ACS Nano, vol.4, issue.8, pp.4539-4550, 2010.

M. Liong, Multifunctional Inorganic Nanoparticles for Imaging, Targeting, and Drug Delivery, vol.2, pp.889-896, 2008.

H. Yamada, C. Urata, Y. Aoyama, S. Osada, Y. Yamauchi et al., « Preparation of Colloidal Mesoporous Silica Nanoparticles with Different Diameters and Their Unique Degradation Behavior in Static Aqueous Systems, Chemistry of Materials, vol.24, issue.8, pp.1462-1471

L. T. Zhuravlev, « The surface chemistry of amorphous silica, Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol.173, pp.1-38, 2000.

A. Giaya and R. W. Thompson, Water confined in cylindrical micropores, vol.117, pp.3464-3475, 2002.

I. Brovchenko, A. Geiger, and E. A. Oleinikova, « Water in nanopores. I. Coexistence curves from Gibbs ensemble Monte Carlo simulations, The Journal of Chemical Physics, vol.120, issue.4, 1958.

T. M. Truskett, P. G. Debenedetti, S. Torquato, and . Thermodynamic, The Journal of Chemical Physics, vol.114, issue.5, pp.2401-2418, 2001.

P. Gallo, M. A. Ricci, and M. Rovere, « Layer analysis of the structure of water confined in vycor glass, The Journal of Chemical Physics, vol.116, issue.1, p.342, 2002.

D. S. Eisenberg and W. Kauzmann, The structure and properties of water, 2005.

M. Chaplin, Water structure and science, 2010.

S. Kittaka, Y. Ueda, F. Fujisaki, T. Iiyama, and T. Yamaguchi, « Mechanism of freezing of water in contact with mesoporous silicas MCM-41, SBA-15 and SBA-16: role of boundary water of pore outlets in freezing, Physical Chemistry Chemical Physics, vol.13, p.17222, 2011.

C. T. Kresge, M. E. Leonowicz, W. J. Roth, J. C. Vartuli, and J. S. Beck, « Ordered mesoporous molecular sieves synthesized by a liquid-crystal template mechanism, Nature, vol.359, pp.710-712, 1992.

D. Zhao and . Triblock, Copolymer Syntheses of Mesoporous Silica with Periodic 50&nbsp, Science, vol.279, pp.548-552, 1998.

T. Takamuku, M. Yamagami, H. Wakita, Y. Masuda, and T. Yamaguchi, Thermal Property, Structure, and Dynamics of Supercooled Water in Porous Silica by Calorimetry, Neutron Scattering, and NMR Relaxation, vol.101, pp.5730-5739, 1997.

D. C. Steytler, « Neutron Diffraction Study of Cublc Ice Nucleation in a Porous Silica Network, p.2

M. Bellissent-funel, J. Lal, and L. Bosio, Structural study of water confined in porous glass by neutron scattering, vol.98, pp.4246-4252, 1993.

A. Bogdan, M. Kulmala, and N. Avramenko, Reduction of Enthalpy of Fusion and Anomalies during Phase Transitions in Finely Divided Water, vol.81, pp.1042-1045, 1998.

E. Tombari, G. Salvetti, C. Ferrari, and G. P. Johari, Thermodynamic functions of water and ice confined to 2nm radius pores, vol.122, p.104712, 2005.

A. Schreiber, I. Ketelsen, and G. H. Findenegg, « Melting and freezing of water in ordered mesoporous silica materials, Physical Chemistry Chemical Physics, vol.3, issue.7, pp.1185-1195, 2001.

S. Kittaka, S. Ishimaru, M. Kuranishi, T. Matsuda, and T. Yamaguchi, « Enthalpy and interfacial free energy changes of water capillary condensed in mesoporous silica, MCM-41 and SBA-15 », Physical Chemistry Chemical Physics, vol.8, issue.3223, 2006.

S. Kittaka, K. Sou, T. Yamaguchi, and K. Tozaki, Thermodynamic and FTIR studies of supercooled water confined to exterior and interior of mesoporous MCM-41 », Physical Chemistry Chemical Physics, vol.11, p.8538, 2009.

K. Morishige and K. Kawano, Freezing and melting of water in a single cylindrical pore: The pore-size dependence of freezing and melting behavior, The Journal of Chemical Physics, vol.110, issue.10, pp.4867-4872, 1999.

K. Morishige and H. Iwasaki, « X-ray Study of Freezing and Melting of Water Confined within SBA-15, Langmuir, vol.19, issue.7, pp.2808-2811, 2003.

K. Morishige, H. Yasunaga, R. Denoyel, V. Wernert, and . Pore, Blocking-Controlled Freezing of Water in Cagelike Pores of, The Journal of Physical Chemistry C, vol.111, pp.9488-9495, 2007.

J. B. Webber, J. C. Dore, J. H. Strange, R. Anderson, and B. Tohidi, « Plastic ice in confined geometry: the evidence from neutron diffraction and NMR relaxation », Journal of Physics: Condensed Matter, vol.19, p.415117, 2007.

D. Akporiaye, E. W. Hansen, R. Schmidt, and M. Stocker, Water-Saturated Mesoporous MCM-41 Systems Characterized by 1H NMR, vol.98, pp.1926-1928, 1994.

E. W. Hansen, R. Schmidt, M. Sticker, and D. Akporiaye, Water-Saturated Mesoporous MCM-41 Systems Characterized by lH NMR Spin-Lattice Relaxation Times, p.7

K. Yoshida, T. Yamaguchi, S. Kittaka, M. Bellissent-funel, and E. P. Fouquet, « Thermodynamic, structural, and dynamic properties of supercooled water confined in mesoporous MCM-41 studied with calorimetric, neutron diffraction, and neutron spin echo measurements, The Journal of Chemical Physics, vol.129, issue.5, p.54702, 2008.

S. Takahara, Neutron Scattering Study on Dynamics of Water Molecules in MCM-41, vol.103, pp.5814-5819, 1999.

A. Faraone, L. Liu, C. Mou, C. Yen, and S. Chen, « Fragile-to-strong liquid transition in deeply supercooled confined water, The Journal of Chemical Physics, vol.121, p.10843, 2004.

P. I. Ravikovitch, S. C. Domhnaill, A. V. Neimark, F. Schueth, and K. K. Unger, Capillary Hysteresis in Nanopores: Theoretical and Experimental Studies of Nitrogen Adsorption on MCM-41 », Langmuir, vol.11, pp.4765-4772

G. W. Scherer, « Freezing gels », Journal of Non-Crystalline Solids, vol.155, issue.1, pp.1-25, 1993.

G. K. Rennie and J. Clifford, « Melting of ice in porous solids, Journal of the Chemical Society, Faraday Transactions, vol.1, p.680, 1977.

K. Ishikiriyama and M. Todoki, « Evaluation of water in silica pores using differential scanning calorimetry, Thermochimica Acta, vol.256, issue.2, pp.213-226, 1995.

R. Schmidt, E. W. Hansen, M. Stoecker, D. Akporiaye, and O. H. Ellestad, « Pore Size Determination of MCM-51 Mesoporous Materials by means of 1H NMR Spectroscopy, N2 adsorption, and HREM. A Preliminary Study », Journal of the American Chemical Society, vol.117, pp.4049-4056, 1995.

E. W. Hansen, H. C. Gran, and E. J. Sellevold, « Heat of Fusion and Surface Tension of Solids Confined in Porous Materials Derived from a Combined Use of NMR and Calorimetry, The Journal of Physical Chemistry B, vol.101, pp.7027-7032, 1997.

G. H. Findenegg, S. Jähnert, D. Akcakayiran, and A. Schreiber, « Freezing and Melting of Water Confined in Silica Nanopores, ChemPhysChem, vol.9, pp.2651-2659, 2008.

K. Modig, B. G. Pfrommer, and B. Halle, « Temperature-Dependent Hydrogen-Bond Geometry in Liquid Water, Physical Review Letters, vol.90, issue.7, 2003.

B. Grünberg, Hydrogen Bonding of Water Confined in Mesoporous Silica MCM-41 and SBA-15 Studied by 1 H Solid-State NMR, vol.10, pp.5689-5696, 2004.

P. Smirnov, T. Yamaguchi, S. Kittaka, S. Takahara, and Y. Kuroda, « X-ray Diffraction Study of Water Confined in Mesoporous MCM-41 Materials over a Temperature Range of 223-298 K », J. Phys.Chem. B, vol.104, pp.5498-5504, 2000.

K. Yamanaka, T. Yamaguchi, and H. Wakita, « Structure of water in the liquid and supercritical states by rapid x-ray diffractometry using an imaging plate detector, The Journal of Chemical Physics, vol.101, issue.11, pp.9830-9836

G. W. Höhne, W. Hemminger, and H. Flammersheim, Types of Differential Scanning Calorimeters », in Differential Scanning Calorimetry, pp.7-20, 1996.

P. Claudy, Analyse calorimétrique différentielle: Théorie et applications de la d.s.c. Paris; Londres: Editions TEC & DOC, 2005.

A. Guinier, X-ray diffraction in crystals, imperfect crystals, and amorphous bodies, 1994.

I. Jeong, R. H. Heffner, M. J. Graf, and S. J. Billinge, « Lattice dynamics and correlated atomic motion from the atomic pair distribution function, Physical Review B, vol.67, issue.10, 2003.

. Th, S. J. Proffen, T. Billinge, D. Egami, and . Louca, « Structural analysis of complex materials using the atomic pair distribution function -a practical guide, Zeitschrift für Kristallographie -Crystalline Materials, vol.218, 2003.

K. Page, « Direct observation of the structure of gold nanoparticles by total scattering powder neutron diffraction, Chemical Physics Letters, vol.393, pp.385-388, 2004.

T. Egami and S. J. Billinge, Underneath the Bragg peaks: structural analysis of complex materials, 2012.

E. Lorch, « Neutron diffraction by germania, silica and radiation-damaged silica glasses », Journal of Physics C: Solid State Physics, vol.2, issue.2, pp.229-237, 1969.

A. K. Soper and E. R. Barney, On the use of modification functions when Fourier transforming total scattering data, Journal of Applied Crystallography, vol.45, issue.6, pp.1314-1317

X. Qiu, J. W. Thompson, and S. J. Billinge, « PDFgetX2 : a GUI-driven program to obtain the pair distribution function from X-ray powder diffraction data, Journal of Applied Crystallography, vol.37, issue.4, pp.678-678, 2004.

R. B. Neder and T. Proffen, Diffuse scattering and defect structure simulations: a cook book using the program DISCUS, 2008.

I. Jeong, T. Proffen, F. Mohiuddin-jacobs, and S. J. Billinge, Measuring Correlated Atomic Motion Using X-ray Diffraction, vol.103, pp.921-924, 1999.

. Th, S. J. Proffen, «. Billinge, and . Pdffit, a program for full profile structural refinement of the atomic pair distribution function, Journal of Applied Crystallography, vol.32, issue.3, pp.572-575, 1999.

C. L. Farrow, « PDFfit2 and PDFgui: computer programs for studying nanostructure in crystals », Journal of Physics: Condensed Matter, vol.19, p.335219, 2007.

B. H. Toby and T. Egami, « Accuracy of pair distribution function analysis applied to crystalline and non-crystalline materials, Acta Crystallographica Section A Foundations of Crystallography, vol.48, issue.3, pp.336-346, 1992.

V. K. Pecharsky and P. Y. Zavalij, Fundamentals of powder diffraction and structural characterization of materials, 2, 2009.

R. E. Dinnebier, S. J. Billinge, and É. , Powder diffraction: theory and practice, 2008.

V. I. Korsunskiy, R. B. Neder, A. Hofmann, S. Dembski, C. Graf et al., « Aspects of the modelling of the radial distribution function for small nanoparticles, Journal of Applied Crystallography, vol.40, issue.6, pp.975-985

H. P. Klug and L. E. Alexander, X-ray diffraction procedures for polycrystalline and amorphous materials, 1974.

K. Hsieh, « Étude multi-échelle des changements structuraux et leur influence sur les propriétés optiques de complexes photoactifs encapsulés dans des matrices mésoporeuses, 2013.

H. C. Pollock, The discovery of synchrotron radiation, vol.51, pp.278-280, 1983.

A. Lodini and T. Baudin, Rayonnement synchrotron, rayons X et neutrons au service des matériaux: analyse des contraintes et des textures, 2013.

B. Buras and J. Leciejewicz, A New Method for Neutron Diffraction Crystal Structure Investigations », physica status solidi (b), vol.4, pp.349-355, 1964.

J. Kieffer, D. Karkoulis, and . Pyfai, a versatile library for azimuthal regrouping », Journal of Physics: Conference Series, vol.425, p.202012, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01572836

S. H. Lee and P. J. Rossky, « A comparison of the structure and dynamics of liquid water at hydrophobic and hydrophilic surfaces-a molecular dynamics simulation study, The Journal of Chemical Physics, vol.100, issue.4, pp.3334-3345, 1994.

M. Rovere, M. A. Ricci, D. Vellati, and F. Bruni, « A molecular dynamics simulation of water confined in a cylindrical SiO2 pore, The Journal of Chemical Physics, vol.108, issue.23, pp.9859-9867, 1998.

D. Presti, A. Pedone, G. Mancini, C. Duce, M. R. Tiné et al., « Insights into structural and dynamical features of water at halloysite interfaces probed by DFT and classical molecular dynamics simulations, Physical Chemistry Chemical Physics, vol.18, issue.3, pp.2164-2174, 2016.

M. J. Gillan, D. Alfè, A. Michaelides, and . Perspective, How good is DFT for water?, The Journal of Chemical Physics, vol.144, issue.13, p.130901, 2016.

W. L. Jorgensen, J. Chandrasekhar, J. D. Madura, R. W. Impey, and M. L. Klein, Comparison of simple potential functions for simulating liquid water, vol.79, pp.926-935, 1983.

P. Jedlovszky, I. Bakó, and G. Pálinkás, « Reverse Monte Carlo simulation of liquid water, Chemical Physics Letters, vol.221, issue.2, pp.87036-87041, 1994.

A. K. Soper, « Empirical potential Monte Carlo simulation of fluid structure, Chemical Physics, vol.202, issue.2-3, pp.357-363, 1996.

A. K. Soper, « Partial structure factors from disordered materials diffraction data: An approach using empirical potential structure refinement, Physical Review B, vol.72, issue.10, 2005.

A. K. Soper, Joint structure refinement of x-ray and neutron diffraction data on disordered materials: application to liquid water », Journal of Physics: Condensed Matter, vol.19, p.335206, 2007.

D. A. Keen and R. L. Mcgreevy, « Structural modelling of glasses using reverse Monte Carlo simulation, Nature, vol.344, pp.423-425, 1990.

J. L. Finney, D. T. Bowron, and A. K. Soper, The structure of aqueous solutions of tertiary butanol », vol.12, pp.123-128, 2000.

A. K. Soper, « Determination of the orientational pair correlation function of a molecular liquid from diffraction data, Journal of Molecular Liquids, vol.78, issue.3, pp.179-200, 1998.

A. K. Soper, The radial distribution functions of water and ice from 220 to 673 K and at pressures up to 400 MPa, Chemical Physics, vol.258, issue.2-3, pp.121-137, 2000.

P. L. Bonate, Brief Introduction to Monte Carlo Simulation, Clinical Pharmacokinetics, vol.40, issue.1, pp.15-22, 2001.

N. Metropolis, A. W. Rosenbluth, M. N. Rosenbluth, A. H. Teller, and E. E. Teller, Equation of State Calculations by Fast Computing Machines, vol.21, p.1953

K. C. Chan, C. T. Lenard, and T. M. Mills, An Introduction to Markov Chains, 2012.

I. Nezbeda and J. Kolafa, « Effect of short-and long-range forces on the structure of water: temperature and density dependence, Molecular Physics, vol.97, issue.10, pp.1105-1116, 1999.

Y. Chen and J. D. Weeks, « Local molecular field theory for effective attractions between like charged objects in systems with strong Coulomb interactions, Proceedings of the National Academy of Sciences, vol.103, pp.7560-7565, 2006.

M. P. Allen and D. J. Tildesley, Computer simulation of liquids, 1987.

A. K. Soper, Boroxol rings from diffraction data on vitreous boron trioxide », vol.23, p.365402, 2011.

M. Falkowska, D. T. Bowron, H. Manyar, T. G. Youngs, and C. Hardacre, Confinement Effects on the Benzene Orientational Structure », vol.57, pp.4565-4570, 2018.

A. K. Soper and D. T. Bowron, « Density profile of nitrogen in cylindrical pores of MCM-41, Chemical Physics Letters, vol.683, pp.529-535, 2017.

R. Mancinelli, « Multiscale Approach to the Structural Study of Water Confined in MCM41, The Journal of Physical Chemistry B, vol.113, pp.16169-16177

D. T. Bowron, Building Monte Carlo Models of Glasses Using Neutron and/or Xray Diffraction Data, Procedia Materials Science, vol.7, pp.38-52, 2014.

N. Bchellaoui, Z. Hayat, M. Mami, R. Dorbez-sridi, and E. A. , El Abed, « Microfluidicassisted Formation of Highly Monodisperse and Mesoporous Silica Soft Microcapsules, Scientific Reports, vol.7, issue.1, 2017.

S. Brunauer, P. H. Emmett, and E. E. Teller, « Adsorption of Gases in Multimolecular Layers, Journal of the American Chemical Society, vol.60, issue.2, pp.309-319

S. Kittaka, S. Ishimaru, M. Kuranishi, T. Matsuda, and T. Yamaguchi, « Enthalpy and interfacial free energy changes of water capillary condensed in mesoporous silica, MCM-41 and SBA-15 », Physical Chemistry Chemical Physics, vol.8, issue.3223, 2006.

G. W. Scherer, « Freezing gels », Journal of Non-Crystalline Solids, vol.155, issue.1, pp.1-25, 1993.

W. Thomson and «. Lx, On the equilibrium of vapour at a curved surface of liquid, The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, vol.42, pp.448-452

A. Schreiber, I. Ketelsen, and G. H. Findenegg, « Melting and freezing of water in ordered mesoporous silica materials, Physical Chemistry Chemical Physics, vol.3, issue.7, pp.1185-1195, 2001.

K. Ishikiriyama and M. Todoki, « Evaluation of water in silica pores using differential scanning calorimetry, Thermochimica Acta, vol.256, issue.2, pp.213-226, 1995.

G. H. Findenegg, S. Jähnert, D. Akcakayiran, and A. Schreiber, « Freezing and Melting of Water Confined in Silica Nanopores, ChemPhysChem, vol.9, pp.2651-2659, 2008.

G. K. Rennie and J. Clifford, « Melting of ice in porous solids, Journal of the Chemical Society, Faraday Transactions, vol.1, p.680, 1977.

W. Drost-hansen and F. M. Etzler, « Melting of ice in silica pores, Langmuir, vol.5, issue.6, pp.1439-1441, 1989.

Y. P. Handa, M. Zakrzewski, and C. Fairbridge, Effect of restricted geometries on the structure and thermodynamic properties of ice, vol.96, pp.8594-8599, 1992.

B. Grünberg, Hydrogen Bonding of Water Confined in Mesoporous Silica MCM-41 and SBA-15 Studied by 1 H Solid-State NMR, vol.10, pp.5689-5696, 2004.

P. A. Bonnaud, B. Coasne, R. J. , and -. Pellenq, « Molecular simulation of water confined in nanoporous silica, Journal of Physics: Condensed Matter, vol.22, p.284110

A. Schreiber, I. Ketelsen, and G. H. Findenegg, « Melting and freezing of water in ordered mesoporous silica materials, Physical Chemistry Chemical Physics, vol.3, issue.7, pp.1185-1195, 2001.

T. Takamuku, M. Yamagami, H. Wakita, Y. Masuda, and T. Yamaguchi, Thermal Property, Structure, and Dynamics of Supercooled Water in Porous Silica by Calorimetry, Neutron Scattering, and NMR Relaxation, vol.101, pp.5730-5739, 1997.

G. H. Findenegg, S. Jähnert, D. Akcakayiran, and A. Schreiber, « Freezing and Melting of Water Confined in Silica Nanopores, ChemPhysChem, vol.9, pp.2651-2659, 2008.

K. Ishikiriyama, M. Todoki, and K. Motomura, « Pore Size Distribution (PSD) Measurements of Silica Gels by Means of Differential Scanning Calorimetry, Journal of Colloid and Interface Science, vol.171, issue.1, pp.92-102, 1995.

J. Zanotti, M. Bellissent-funel, and E. Chen, « Experimental evidence of a liquid-liquid transition in interfacial water, Europhysics Letters (EPL), vol.71, issue.1, pp.91-97, 2005.

D. Wallacher and K. Knorr, Melting and freezing of Ar in nanopores, Physical Review B, vol.63, issue.10, 2001.

J. Zanotti, M. Bellissent-funel, and E. Chen, « Experimental evidence of a liquid-liquid transition in interfacial water, Europhysics Letters (EPL), vol.71, issue.1, pp.91-97, 2005.

R. T. Pearson, W. Derbyshire, and «. Nmr, Journal of Colloid and Interface Science, vol.46, issue.2, pp.90007-90008, 1974.

R. Schmidt, E. W. Hansen, M. Stoecker, D. Akporiaye, and O. H. Ellestad, « Pore Size Determination of MCM-51 Mesoporous Materials by means of 1H NMR Spectroscopy, N2 adsorption, and HREM. A Preliminary Study », Journal of the American Chemical Society, vol.117, pp.4049-4056, 1995.

, Comme montre cette figure, ces données présentent un bon accord entre elles. Le F(Q) simulé reproduit les différentes amplitudes des pics des données expérimentales avec de très légers écarts. La d-PDF simulée reproduit les différentes corrélations de paires de la d-PDF expérimentale, Nous observons tout de même des différences notables des intensités des pics

, Plusieurs facteurs peuvent être à l'origine de cette différence d'intensité : i. Les erreurs dus au choix des paramètres utilisés dans la simulation, ii. La modélisation d'un seul pore de l'échantillon étudié (limitation logiciel), iii. Erreurs dus au facteur d'échelle utilisé pour soustraire la contribution de l'échantillon sec

, afin d'étudier les différentes corrélations caractéristiques de ce système. La Figure V-27 montre la fonction de distribution partielle de paires Ow-Si de l'eau confinée dans 62%MCM-41. Nous observons clairement que ces interactions se font à une distance de ~3,75 Å. Ainsi nous pourrons expliquer pourquoi ces interactions sont peu sensibles à la variation de la température (voir d-PDF expérimentale : Figure V-23). Par conséquent, on peut affirmer la participation de cette corrélation dans la contribution du pic à 3,75 Å de la d-PDF. La position de ce pic est cohérente avec des travaux reportés dans la littérature sur l, 2 Fonction de distribution partielle de paires (g(r)) O w -Si Après la validation du modèle calculé par EPSR, nous avons déterminé les fonctions de distribution partielles de paires, g(r)

T. C. Hansen, M. M. Koza, P. Lindner, and W. F. Kuhs, « Formation and annealing of cubic ice: II. Kinetic study », Journal of Physics: Condensed Matter, vol.20, p.285105, 2008.

T. L. Malkin, B. J. Murray, C. G. Salzmann, V. Molinero, S. J. Pickering et al., Stacking disorder in ice I », Physical Chemistry Chemical Physics, vol.17, issue.1, pp.60-76, 2015.

D. , « X-ray studies of the transformation from high-to low-density amorphous water, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol.377, p.2146, 2019.

H. König, Eine kubische Eismodifikation », Zeitschrift für Kristallographie -Crystalline Materials, vol.105, pp.279-286

W. F. Kuhs, D. V. Bliss, J. L. Finney, «. High-resolution, . Neutron-powder et al., Le Journal de Physique Colloques, vol.48, pp.1-631, 1987.

N. D. Lisgarten and M. Blackman, « The Cubic Form of Ice, Nature, vol.178, issue.4523, pp.39-40, 1956.

J. E. Bertie and S. M. Jacobs, « Far-infrared absorption by ices Ih and Ic at 4.3 °K and the powder diffraction pattern of ice Ic, The Journal of Chemical Physics, vol.67, issue.6, p.2445, 1977.

P. Smirnov, T. Yamaguchi, S. Kittaka, S. Takahara, and Y. Kuroda, « X-ray Diffraction Study of Water Confined in Mesoporous MCM-41 Materials over a Temperature Range of 223-298 K », J. Phys.Chem. B, vol.104, issue.23, pp.5498-5504, 2000.

K. Yamanaka, T. Yamaguchi, and H. Wakita, « Structure of water in the liquid and supercritical states by rapid x-ray diffractometry using an imaging plate detector, The Journal of Chemical Physics, vol.101, issue.11, pp.9830-9836

A. K. Soper, Structural transformations in amorphous ice and supercooled water and their relevance to the phase diagram of water, Molecular Physics, vol.106, pp.2053-2076, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00513204

A. K. Soper, « Density profile of water confined in cylindrical pores in MCM-41 silica », Journal of Physics: Condensed Matter, vol.24, issue.6, p.64107

A. K. Soper, « Radical re-appraisal of water structure in hydrophilic confinement, Chemical Physics Letters, vol.590, pp.1-15

E. Stefanutti, L. E. Bove, G. Lelong, M. A. Ricci, A. K. Soper et al., « Ice crystallization observed in highly supercooled confined water, Physical Chemistry Chemical Physics, vol.21, issue.9, pp.4931-4938, 2019.

W. A. Kamitakahara, A. Faraone, K. Liu, and C. Mou, « Temperature dependence of structure and density for D 2 O confined in MCM-41-S », Journal of Physics: Condensed Matter, vol.24, issue.6, p.64106

G. H. Findenegg, S. Jähnert, D. Akcakayiran, and A. Schreiber, « Freezing and Melting of Water Confined in Silica Nanopores, ChemPhysChem, vol.9, pp.2651-2659, 2008.

X. Qiu, J. W. Thompson, and S. J. Billinge, « PDFgetX2 : a GUI-driven program to obtain the pair distribution function from X-ray powder diffraction data, Journal of Applied Crystallography, vol.37, issue.4, pp.678-678, 2004.

F. Bruni, M. A. Ricci, and A. K. Soper, « Water confined in Vycor glass. I. A neutron diffraction study, The Journal of Chemical Physics, vol.109, issue.4, pp.1478-1485, 1998.

A. Fouzri, R. Dorbez-sridi, S. Nasr, and M. Oumezzine, « Water-silica gel interactions, X-ray diffraction study at room and low temperature, Biomolecular Engineering, vol.19, issue.2-6, pp.43-49, 2002.

A. Fouzri, R. Dorbez-sridi, M. Oumezzine, and A. Missaoui, « Water confined in silica gel at room temperature, X-ray diffraction study, International Journal of Inorganic Materials, vol.3, issue.8, pp.1315-1317, 2001.

B. Grünberg, Hydrogen Bonding of Water Confined in Mesoporous Silica MCM-41 and SBA-15 Studied by 1 H Solid-State NMR, vol.10, pp.5689-5696, 2004.

S. Takahara, N. Sumiyama, S. Kittaka, T. Yamaguchi, and M. , Bellissent-Funel, « Neutron Scattering Study on Dynamics of Water Molecules in MCM-41. 2. Determination of Translational Diffusion Coefficient, The Journal of Physical Chemistry B, vol.109, pp.11231-11239, 2005.

A. Figoli, J. Hoinkis, S. A. Altinkaya, and J. Bundschuh, Application of nanotechnology in membranes for water treatment, 2017.

A. Schreiber, I. Ketelsen, and G. H. Findenegg, « Melting and freezing of water in ordered mesoporous silica materials, Physical Chemistry Chemical Physics, vol.3, issue.7, pp.1185-1195, 2001.

K. Ishikiriyama and M. Todoki, « Evaluation of water in silica pores using differential scanning calorimetry, Thermochimica Acta, vol.256, issue.2, pp.213-226, 1995.

M. Bellissent-funel, R. Sridi-dorbez, and E. L. Bosio, « X-ray and neutron scattering studies of the structure of water at a hydrophobic surface, The Journal of Chemical Physics, vol.104, pp.10023-10029, 1996.

M. Bellissent-funel, J. Lal, and L. Bosio, Structural study of water confined in porous glass by neutron scattering, vol.98, pp.4246-4252, 1993.

A. K. Soper, F. Bruni, and M. A. Ricci, « Water confined in Vycor glass. II. Excluded volume effects on the radial distribution functions, The Journal of Chemical Physics, vol.109, issue.4, pp.1486-1494, 1998.

G. K. Rennie and J. Clifford, « Melting of ice in porous solids, Journal of the Chemical Society, Faraday Transactions, vol.1, p.680, 1977.

T. Takamuku, M. Yamagami, H. Wakita, Y. Masuda, and T. Yamaguchi, Thermal Property, Structure, and Dynamics of Supercooled Water in Porous Silica by Calorimetry, Neutron Scattering, and NMR Relaxation, vol.101, pp.5730-5739, 1997.

S. H. Lee and P. J. Rossky, « A comparison of the structure and dynamics of liquid water at hydrophobic and hydrophilic surfaces-a molecular dynamics simulation study, The Journal of Chemical Physics, vol.100, issue.4, pp.3334-3345, 1994.

R. Mancinelli, « Multiscale Approach to the Structural Study of Water Confined in MCM41, The Journal of Physical Chemistry B, vol.113, pp.16169-16177

N. Bchellaoui, Z. Hayat, M. Mami, R. Dorbez-sridi, and E. A. , El Abed, « Microfluidicassisted Formation of Highly Monodisperse and Mesoporous Silica Soft Microcapsules, Scientific Reports, vol.7, issue.1, 2017.

H. Thompson, A. K. Soper, M. A. Ricci, F. Bruni, and N. T. Skipper, The Three-Dimensional Structure of Water Confined in Nanoporous Vycor Glass, vol.111, p.5610, 2007.

D. T. Bowron, Building Monte Carlo Models of Glasses Using Neutron and/or Xray Diffraction Data, Procedia Materials Science, vol.7, pp.38-52, 2014.

M. A. Karakassides, A. Saranti, and E. I. Koutselas, « Preparation and structural study of binary phosphate glasses with high calcium and/or magnesium content », Journal of Non-Crystalline Solids, vol.347, issue.1-3, pp.69-79, 2004.

N. Metropolis, A. W. Rosenbluth, M. N. Rosenbluth, A. H. Teller, and E. E. Teller, Equation of State Calculations by Fast Computing Machines, vol.21, p.1953

M. Rovere, M. A. Ricci, D. Vellati, and F. Bruni, « A molecular dynamics simulation of water confined in a cylindrical SiO2 pore, The Journal of Chemical Physics, vol.108, issue.23, pp.9859-9867, 1998.

K. Yoshida, T. Yamaguchi, S. Kittaka, M. Bellissent-funel, and E. P. Fouquet, « Thermodynamic, structural, and dynamic properties of supercooled water confined in mesoporous MCM-41 studied with calorimetric, neutron diffraction, and neutron spin echo measurements, The Journal of Chemical Physics, vol.129, issue.5, p.54702, 2008.

R. Mancinelli, F. Bruni, and M. A. Ricci, « Controversial Evidence on the Point of Minimum Density in Deeply Supercooled Confined Water, The Journal of Physical Chemistry Letters, vol.1, issue.8, pp.1277-1282

P. Gallo, M. Rovere, and S. Chen, « Anomalous dynamics of water confined in MCM-41 at different hydrations », Journal of Physics: Condensed Matter, vol.22, p.284102

J. Jelassi, « Structural studies of water in hydrophilic and hydrophobic mesoporous silicas: An x-ray and neutron diffraction study at 297 K », The Journal of Chemical Physics, vol.134, issue.6, p.64509, 2011.

P. Gallo, M. A. Ricci, and M. Rovere, « Layer analysis of the structure of water confined in vycor glass, The Journal of Chemical Physics, vol.116, issue.1, p.342, 2002.

, ANNEXE B Fonction de modification

, Afin de réduire les ondulations de terminaison qui se produisent en raison de la plage finie et des statistiques de comptage des données de diffusion, on utilise une fonction de modification

, Cette fonction a été proposée à l'origine par Lorch en 1969 [1], et elle permet de mettre la densité d'un point appartenant à l'espace réel (g(ri)) dans une géométrie sphérique mince de rayon ?0 centré dans ri. L'intensité sera ensuite moyennée sur la direction de ri

, Ensuite une nouvelle version pour cette fonction a été proposée en 2011 par Soper et Barney

, Au lieu de définir g(ri) par une géométrie sphérique, elle a été étalée uniformément dans les trois dimensions de l'espace sur une sphère solide de rayon ?1

, Avec ?1=4,4934/Qmax

E. Lorch, « Neutron diffraction by germania, silica and radiation-damaged silica glasses, Journal of Physics C: Solid State Physics, vol.2, issue.2, pp.229-237, 1969.

A. K. Soper and E. R. Barney, Extracting the pair distribution function from whitebeam X-ray total scattering data, Journal of Applied Crystallography, vol.44, pp.714-726, 2011.

A. K. Soper and E. R. Barney, On the use of modification functions when Fourier transforming total scattering data, Journal of Applied Crystallography, vol.45, issue.6, pp.1314-1317

, Le bioverre solgel a été synthétisé en utilisant la technique sol-gel standard, il a été élaboré en utilisant un tensioactif appelé Pluronic ® P123, par un processus en deux étapes d'auto-assemblage catalysé par un acide combiné avec un traitement la méthode d'évaporation de solvant et l'utilisation de gouttelettes hautement monodispersées comme modèles souples. Cette approche de microfluidique permet la fabrication des bioverres mésoporeux formés par des microsphères bien définies et hautement monodispersées

;. L'orthosilicate-de-tétraéthyle and . Teos)-(99%;-sigma-aldrich, ) a été utilisé comme modèle de mésostructuration. Le précurseur de sol de silice a été préparé en dissolvant, sous agitation, Pluronic P123 (PEG-PPG-PEG, Masse molaire: 5800 g/mol

, jusqu'à ce que la solution devient limpide. Ensuite, 3,6 g de TEOS, 0,16 g de TEP et 0,53 g de CaCO3 ont été ajoutés respectivement, un par un, à la solution sous agitation constante. Après agitation pendant 3 heures, la synthèse sera achevée par la méthode microfluidique, M HNO3 et 5 ml d'eau distillée

. Bibliographie,

N. Letaïef, A. Lucas-girot, H. Oudadesse, R. Dorbez-sridi, and E. P. Boullay, « Investigation of the surfactant type effect on characteristics and bioactivity of new mesoporous bioactive glass in the ternary system SiO2-CaO-P2O5: Structural, textural and reactivity studies, vol.195, pp.102-111, 2014.

N. Bchellaoui, Z. Hayat, M. Mami, R. Dorbez-sridi, and E. A. , El Abed, « Microfluidicassisted Formation of Highly Monodisperse and Mesoporous Silica Soft Microcapsules, Scientific Reports, vol.7, issue.1, 2017.