Fully automated production of sodium [(18)F]fluoride on AllInOne and miniAllInOne synthesizers.

A fully automated production of the imaging agent sodium [(18)F]fluoride ([(18)F]NaF) on two different modules commercialized by Trasis®, the AllInOne and the miniAllInOne, is reported. Both modules allow to prepare [(18)F]NaF in good radiochemical yield (around 97%) in less than 4min with the same specifications. Quality control of [(18)F]NaF produced by this way was performed according to the US and European Pharmacopeia monograph requirements.

Keywords

Positron emission tomography Radiopharmaceutical Sodium [18F]fluoride [18F]NaF

Domains

Chemical Sciences

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https://hal.univ-lorraine.fr/hal-01496025

Submitted on : Monday, March 27, 2017-10:52:34 AM

Last modification on : Tuesday, October 29, 2024-6:22:15 PM

Dates and versions

hal-01496025 , version 1 (27-03-2017)

Identifiers

HAL Id : hal-01496025 , version 1
DOI : 10.1016/j.apradiso.2015.04.016
PUBMED : 26002274

Cite

Charlotte Collet, Muhammad Otabashi, Fabrice Giacomelli, Nicolas Veran, Gilles Karcher, et al.. Fully automated production of sodium [(18)F]fluoride on AllInOne and miniAllInOne synthesizers.. Applied Radiation and Isotopes, 2015, 102, pp.87-92. ⟨10.1016/j.apradiso.2015.04.016⟩. ⟨hal-01496025⟩

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