Facile Synthesis of Hydrazine Derivatives of 5H-Pyrrolo[3,4-b]pyrazine and 1H-Pyrrolo[3,4-b]quinoxaline

Abstract : A convenient and efficient route for the chemoselective synthesis of carbohydrazide, arenesulfonylhydrazide, and thiosemicarbazone derivatives of 5H-pyrrolo[3,4-b]pyrazine and 1H-pyrrolo[3,4-b]quinoxaline from the corresponding dinitriles and substituted hydrazines was elaborated. The synthesis of starting pyrazine-2,3-dicarbonitrile was sufficiently improved by using concentrated HCl as a catalyst.
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SYNTHESIS, Georg Thieme Verlag, 2013, 45 (24), pp.3375-3382. 〈10.1055/s-0033-1340042〉
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https://hal.univ-lorraine.fr/hal-01498208
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Soumis le : mercredi 29 mars 2017 - 16:52:34
Dernière modification le : mardi 24 juillet 2018 - 16:43:04

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Olga V. Hordiyenko, Igor V. Rudenko, Irina A. Zamkova, Oleksandr V. Denisenko, Angelina V. Biitseva, et al.. Facile Synthesis of Hydrazine Derivatives of 5H-Pyrrolo[3,4-b]pyrazine and 1H-Pyrrolo[3,4-b]quinoxaline. SYNTHESIS, Georg Thieme Verlag, 2013, 45 (24), pp.3375-3382. 〈10.1055/s-0033-1340042〉. 〈hal-01498208〉

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