Synthesis and Molecular modeling of some new chalcones derived from coumarine as CDC25 phosphatases inhibitors - Université de Lorraine Access content directly
Journal Articles Mediterranean Journal of Chemistry Year : 2016

Synthesis and Molecular modeling of some new chalcones derived from coumarine as CDC25 phosphatases inhibitors

Abstract

New chalcones derived from coumarines were synthesized and tested as CDC25 phosphatase inhibitors. Molecular modeling of these new compounds was also presented in aim to study the mode of compounds orientation within CDC25 A and B. The reversibility of compounds 3, 4 and 5 was confirmed by application of MALDI–TOFMS technique.

Dates and versions

hal-01519921 , version 1 (09-05-2017)

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Delel Dridi, Ahmed B. Abdelwahab, Emilie Bana, Patrick Chaimbault, Faouzi Meganem, et al.. Synthesis and Molecular modeling of some new chalcones derived from coumarine as CDC25 phosphatases inhibitors. Mediterranean Journal of Chemistry, 2016, 5 (1), pp.323 - 330. ⟨10.13171/mjc.5.1/0160112/kirsch⟩. ⟨hal-01519921⟩
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