Skip to Main content Skip to Navigation
New interface
Journal articles

L -Alanylglycylhistamine dihydrochloride

Abstract : In the title compound {systematic name: 4-[2-({N-[(2S)-2-ammonio­propano­yl]glyc­yl}amino)­eth­yl]-1H-imidazol-3-ium dichloride}, C10H19N5O22+·2Cl-, the pseudo-tripeptide L-alanyl­glycyl­histamine is protonated at both the terminal amino group and the histidine N2 atom. The resulting positive charges are neutralized by two chloride anions. In the crystal, the organic cation adopts a twisted conformation about the CH2-CH2 bond of histamine and about the C-N bond in the main chain, stabilized by a short intra­molecular C-H...O contact. In the crystal, N+-H...O and N+-H...Cl- hydrogen bonds link the mol­ecules into infinite sheets parallel to the (100) plane. The stacking of these sheets along the a axis is supported by Namide-H...Cl- hydrogen bonds.
Document type :
Journal articles
Complete list of metadata
Contributor : CRM2 UL Connect in order to contact the contributor
Submitted on : Friday, May 12, 2017 - 3:22:16 PM
Last modification on : Monday, January 31, 2022 - 5:22:09 PM

Intranet access




Katalin Selmeczi, Patrick Gizzi, Emmanuel Wenger, Benoît Henry. L -Alanylglycylhistamine dihydrochloride. Acta Crystallographica Section E : Structure Reports Online [2001-2014], 2012, 68 (6), pp.o1917 - o1918. ⟨10.1107/S1600536812023562⟩. ⟨hal-01521951⟩



Record views