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Article Dans Une Revue Archives de Pédiatrie Année : 2016

Sandifer's syndrome in a 5-month-old child with suspicion of infantile spasms

Syndrome de Sandifer chez une enfant de 5 mois admise pour des spasmes épileptiques

Résumé

Sandifer's syndrome is a dystonic movement disorder in infants with gastroesophageal reflux (GER). It is probably misdiagnosed as epileptic seizures. We report the case of a 5-month-old infant with no past medical history admitted to a pediatric unit for suspicion of infantile spasms. She presented with dystonic movements of the upper left limb with left blepharospasm and an occasional dystonic head posture. Physical examination, EEG, brain MRI, and blood analysis were normal. Since the baby experienced regurgitations, Sandifer's syndrome was suspected and confirmed by 24-h esophageal pH monitoring that documented pathological GER. The dystonic symptoms quickly disappeared under treatment with thickened infant formula and sodium alginate. Infantile spasms remain the first diagnosis to explore with axial or para-axial dystonic postural events. Sandifer's syndrome should be retained when neurological investigations are normal and abnormal movements disappear under treatment of proven GER. Prognosis is excellent.
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Dates et versions

hal-01714463 , version 1 (21-02-2018)

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Citer

Maëlle Wirth, C. Bonnemains, J. Auger, Emmanuel Raffo, Bruno Leheup. Syndrome de Sandifer chez une enfant de 5 mois admise pour des spasmes épileptiques. Archives de Pédiatrie, 2016, 23 (2), pp.159-162. ⟨10.1016/j.arcped.2015.11.006⟩. ⟨hal-01714463⟩
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